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Items: 1 to 50 of 163

1.

UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites.

Akimov V, Barrio-Hernandez I, Hansen SVF, Hallenborg P, Pedersen AK, Bekker-Jensen DB, Puglia M, Christensen SDK, Vanselow JT, Nielsen MM, Kratchmarova I, Kelstrup CD, Olsen JV, Blagoev B.

Nat Struct Mol Biol. 2018 Jul;25(7):631-640. doi: 10.1038/s41594-018-0084-y. Epub 2018 Jul 2.

PMID:
29967540
2.

Molecular basis of Tousled-Like Kinase 2 activation.

Mortuza GB, Hermida D, Pedersen AK, Segura-Bayona S, López-Méndez B, Redondo P, Rüther P, Pozdnyakova I, Garrote AM, Muñoz IG, Villamor-Payà M, Jauset C, Olsen JV, Stracker TH, Montoya G.

Nat Commun. 2018 Jun 28;9(1):2535. doi: 10.1038/s41467-018-04941-y.

3.

PKD Phosphorylation as Novel Pathway of KV11.1 Regulation.

Steffensen AB, Bomholtz SH, Andersen MN, Olsen JV, Mutsaers N, Lundegaard PR, Lundby A, Schmitt N.

Cell Physiol Biochem. 2018 Jun 27;47(4):1742-1750. doi: 10.1159/000491007. [Epub ahead of print]

4.

Generic Workflow for Mapping of Complex Disulfide Bonds Using In-Source Reduction and Extracted Ion Chromatograms from Data-Dependent Mass Spectrometry.

Cramer CN, Kelstrup CD, Olsen JV, Haselmann KF, Nielsen PK.

Anal Chem. 2018 Jul 3;90(13):8202-8210. doi: 10.1021/acs.analchem.8b01603. Epub 2018 Jun 22.

PMID:
29878755
5.

Palaeoproteomic Profiling of Conservation Layers on a 14th Century Italian Wall Painting.

Mackie M, Rüther P, Samodova D, Di Gianvincenzo F, Granzotto C, Lyon D, Peggie DA, Howard H, Harrison L, Jensen LJ, Olsen JV, Cappellini E.

Angew Chem Int Ed Engl. 2018 Jun 18;57(25):7369-7374. doi: 10.1002/anie.201713020. Epub 2018 Apr 26.

6.

Benchmarking common quantification strategies for large-scale phosphoproteomics.

Hogrebe A, von Stechow L, Bekker-Jensen DB, Weinert BT, Kelstrup CD, Olsen JV.

Nat Commun. 2018 Mar 13;9(1):1045. doi: 10.1038/s41467-018-03309-6.

7.

Large-Scale Phosphoproteomics Reveals Shp-2 Phosphatase-Dependent Regulators of Pdgf Receptor Signaling.

Batth TS, Papetti M, Pfeiffer A, Tollenaere MAX, Francavilla C, Olsen JV.

Cell Rep. 2018 Mar 6;22(10):2784-2796. doi: 10.1016/j.celrep.2018.02.038.

8.

Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.

Bozal-Basterra L, Martín-Ruíz I, Pirone L, Liang Y, Sigurðsson JO, Gonzalez-Santamarta M, Giordano I, Gabicagogeascoa E, de Luca A, Rodríguez JA, Wilkie AOM, Kohlhase J, Eastwood D, Yale C, Olsen JV, Rauchman M, Anderson KV, Sutherland JD, Barrio R.

Am J Hum Genet. 2018 Feb 1;102(2):249-265. doi: 10.1016/j.ajhg.2017.12.017.

9.

Control of endothelial cell tube formation by Notch ligand intracellular domain interactions with activator protein 1 (AP-1).

Forghany Z, Robertson F, Lundby A, Olsen JV, Baker DA.

J Biol Chem. 2018 Jan 26;293(4):1229-1242. doi: 10.1074/jbc.M117.819045. Epub 2017 Dec 1.

PMID:
29196606
10.

Performance Evaluation of the Q Exactive HF-X for Shotgun Proteomics.

Kelstrup CD, Bekker-Jensen DB, Arrey TN, Hogrebe A, Harder A, Olsen JV.

J Proteome Res. 2018 Jan 5;17(1):727-738. doi: 10.1021/acs.jproteome.7b00602. Epub 2017 Dec 20.

PMID:
29183128
11.

Proteomics Reveals Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress.

Munk S, Sigurðsson JO, Xiao Z, Batth TS, Franciosa G, von Stechow L, Lopez-Contreras AJ, Vertegaal ACO, Olsen JV.

Cell Rep. 2017 Oct 10;21(2):546-558. doi: 10.1016/j.celrep.2017.09.059.

12.

Proteomic profiling of archaeological human bone.

Sawafuji R, Cappellini E, Nagaoka T, Fotakis AK, Jersie-Christensen RR, Olsen JV, Hirata K, Ueda S.

R Soc Open Sci. 2017 Jun 7;4(6):161004. doi: 10.1098/rsos.161004. eCollection 2017 Jun.

13.

An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes.

Bekker-Jensen DB, Kelstrup CD, Batth TS, Larsen SC, Haldrup C, Bramsen JB, Sørensen KD, Høyer S, Ørntoft TF, Andersen CL, Nielsen ML, Olsen JV.

Cell Syst. 2017 Jun 28;4(6):587-599.e4. doi: 10.1016/j.cels.2017.05.009. Epub 2017 Jun 7.

14.

KITD816V Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma.

Phung B, Kazi JU, Lundby A, Bergsteinsdottir K, Sun J, Goding CR, Jönsson G, Olsen JV, Steingrímsson E, Rönnstrand L.

Mol Cancer Res. 2017 Sep;15(9):1265-1274. doi: 10.1158/1541-7786.MCR-17-0149. Epub 2017 Jun 5.

PMID:
28584020
15.

Cylindromatosis Tumor Suppressor Protein (CYLD) Deubiquitinase is Necessary for Proper Ubiquitination and Degradation of the Epidermal Growth Factor Receptor.

Sanchez-Quiles V, Akimov V, Osinalde N, Francavilla C, Puglia M, Barrio-Hernandez I, Kratchmarova I, Olsen JV, Blagoev B.

Mol Cell Proteomics. 2017 Aug;16(8):1433-1446. doi: 10.1074/mcp.M116.066423. Epub 2017 Jun 1.

PMID:
28572092
16.

Complete Mapping of Complex Disulfide Patterns with Closely-Spaced Cysteines by In-Source Reduction and Data-Dependent Mass Spectrometry.

Cramer CN, Kelstrup CD, Olsen JV, Haselmann KF, Nielsen PK.

Anal Chem. 2017 Jun 6;89(11):5949-5957. doi: 10.1021/acs.analchem.7b00424. Epub 2017 May 9.

PMID:
28453249
17.

Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer.

Francavilla C, Lupia M, Tsafou K, Villa A, Kowalczyk K, Rakownikow Jersie-Christensen R, Bertalot G, Confalonieri S, Brunak S, Jensen LJ, Cavallaro U, Olsen JV.

Cell Rep. 2017 Mar 28;18(13):3242-3256. doi: 10.1016/j.celrep.2017.03.015.

18.

Percutaneous Tricuspid Valve Regurgitation Repair With the MitraClip Device Using an Edge-to-Edge Bicuspidization Technique.

Gafoor S, Petrescu OM, Lehr EJ, Puls C, Zhang M, Petersen JL 2nd, Olsen JV, Penev I, Agrawal M, Sharma R, Barnhart G.

J Invasive Cardiol. 2017 Mar;29(3):E30-E36.

19.

The ubiquitin ligase Cullin5SOCS2 regulates NDR1/STK38 stability and NF-κB transactivation.

Paul I, Batth TS, Iglesias-Gato D, Al-Araimi A, Al-Haddabi I, Alkharusi A, Norstedt G, Olsen JV, Zadjali F, Flores-Morales A.

Sci Rep. 2017 Feb 20;7:42800. doi: 10.1038/srep42800.

20.

A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation.

Pirone L, Xolalpa W, Sigurðsson JO, Ramirez J, Pérez C, González M, de Sabando AR, Elortza F, Rodriguez MS, Mayor U, Olsen JV, Barrio R, Sutherland JD.

Sci Rep. 2017 Jan 18;7:40756. doi: 10.1038/srep40756.

21.

Combinatorial Drug Screening Identifies Ewing Sarcoma-specific Sensitivities.

Radic-Sarikas B, Tsafou KP, Emdal KB, Papamarkou T, Huber KV, Mutz C, Toretsky JA, Bennett KL, Olsen JV, Brunak S, Kovar H, Superti-Furga G.

Mol Cancer Ther. 2017 Jan;16(1):88-101. doi: 10.1158/1535-7163.MCT-16-0235. Epub 2016 Nov 15.

22.

Proteomics insights into DNA damage response and translating this knowledge to clinical strategies.

von Stechow L, Olsen JV.

Proteomics. 2017 Feb;17(3-4). doi: 10.1002/pmic.201600018. Epub 2016 Dec 12. Review.

23.

Metaproteomics of saliva identifies human protein markers specific for individuals with periodontitis and dental caries compared to orally healthy controls.

Belstrøm D, Jersie-Christensen RR, Lyon D, Damgaard C, Jensen LJ, Holmstrup P, Olsen JV.

PeerJ. 2016 Sep 14;4:e2433. doi: 10.7717/peerj.2433. eCollection 2016.

24.

Protein sequences bound to mineral surfaces persist into deep time.

Demarchi B, Hall S, Roncal-Herrero T, Freeman CL, Woolley J, Crisp MK, Wilson J, Fotakis A, Fischer R, Kessler BM, Rakownikow Jersie-Christensen R, Olsen JV, Haile J, Thomas J, Marean CW, Parkington J, Presslee S, Lee-Thorp J, Ditchfield P, Hamilton JF, Ward MW, Wang CM, Shaw MD, Harrison T, Domínguez-Rodrigo M, MacPhee R, Kwekason A, Ecker M, Kolska Horwitz L, Chazan M, Kröger R, Thomas-Oates J, Harding JH, Cappellini E, Penkman K, Collins MJ.

Elife. 2016 Sep 27;5. pii: e17092. doi: 10.7554/eLife.17092.

25.

52 Genetic Loci Influencing Myocardial Mass.

van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano MT, Wang X, Mateo Leach I, Eijgelsheim M, Sotoodehnia N, Hayward C, Sorice R, Meirelles O, Lyytikäinen LP, Polašek O, Tanaka T, Arking DE, Ulivi S, Trompet S, Müller-Nurasyid M, Smith AV, Dörr M, Kerr KF, Magnani JW, Del Greco M F, Zhang W, Nolte IM, Silva CT, Padmanabhan S, Tragante V, Esko T, Abecasis GR, Adriaens ME, Andersen K, Barnett P, Bis JC, Bodmer R, Buckley BM, Campbell H, Cannon MV, Chakravarti A, Chen LY, Delitala A, Devereux RB, Doevendans PA, Dominiczak AF, Ferrucci L, Ford I, Gieger C, Harris TB, Haugen E, Heinig M, Hernandez DG, Hillege HL, Hirschhorn JN, Hofman A, Hubner N, Hwang SJ, Iorio A, Kähönen M, Kellis M, Kolcic I, Kooner IK, Kooner JS, Kors JA, Lakatta EG, Lage K, Launer LJ, Levy D, Lundby A, Macfarlane PW, May D, Meitinger T, Metspalu A, Nappo S, Naitza S, Neph S, Nord AS, Nutile T, Okin PM, Olsen JV, Oostra BA, Penninger JM, Pennacchio LA, Pers TH, Perz S, Peters A, Pinto YM, Pfeufer A, Pilia MG, Pramstaller PP, Prins BP, Raitakari OT, Raychaudhuri S, Rice KM, Rossin EJ, Rotter JI, Schafer S, Schlessinger D, Schmidt CO, Sehmi J, Silljé HHW, Sinagra G, Sinner MF, Slowikowski K, Soliman EZ, Spector TD, Spiering W, Stamatoyannopoulos JA, Stolk RP, Strauch K, Tan ST, Tarasov KV, Trinh B, Uitterlinden AG, van den Boogaard M, van Duijn CM, van Gilst WH, Viikari JS, Visscher PM, Vitart V, Völker U, Waldenberger M, Weichenberger CX, Westra HJ, Wijmenga C, Wolffenbuttel BH, Yang J, Bezzina CR, Munroe PB, Snieder H, Wright AF, Rudan I, Boyer LA, Asselbergs FW, van Veldhuisen DJ, Stricker BH, Psaty BM, Ciullo M, Sanna S, Lehtimäki T, Wilson JF, Bandinelli S, Alonso A, Gasparini P, Jukema JW, Kääb S, Gudnason V, Felix SB, Heckbert SR, de Boer RA, Newton-Cheh C, Hicks AA, Chambers JC, Jamshidi Y, Visel A, Christoffels VM, Isaacs A, Samani NJ, de Bakker PIW.

J Am Coll Cardiol. 2016 Sep 27;68(13):1435-1448. doi: 10.1016/j.jacc.2016.07.729.

26.

miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells.

Rasmussen MH, Lyskjær I, Jersie-Christensen RR, Tarpgaard LS, Primdal-Bengtson B, Nielsen MM, Pedersen JS, Hansen TP, Hansen F, Olsen JV, Pfeiffer P, Ørntoft TF, Andersen CL.

Nat Commun. 2016 Aug 16;7:12436. doi: 10.1038/ncomms12436.

27.

A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase.

Hertz EPT, Kruse T, Davey NE, López-Méndez B, Sigurðsson JO, Montoya G, Olsen JV, Nilsson J.

Mol Cell. 2016 Aug 18;63(4):686-695. doi: 10.1016/j.molcel.2016.06.024. Epub 2016 Jul 21.

28.

An Innate Immunity Pathway in the Moss Physcomitrella patens.

Bressendorff S, Azevedo R, Kenchappa CS, Ponce de León I, Olsen JV, Rasmussen MW, Erbs G, Newman MA, Petersen M, Mundy J.

Plant Cell. 2016 Jun;28(6):1328-42. doi: 10.1105/tpc.15.00774. Epub 2016 Jun 7.

29.

Cetuximab Resistance in Squamous Carcinomas of the Upper Aerodigestive Tract Is Driven by Receptor Tyrosine Kinase Plasticity: Potential for mAb Mixtures.

Kjær I, Lindsted T, Fröhlich C, Olsen JV, Horak ID, Kragh M, Pedersen MW.

Mol Cancer Ther. 2016 Jul;15(7):1614-26. doi: 10.1158/1535-7163.MCT-15-0565. Epub 2016 May 11.

30.

Analytic framework for peptidomics applied to large-scale neuropeptide identification.

Secher A, Kelstrup CD, Conde-Frieboes KW, Pyke C, Raun K, Wulff BS, Olsen JV.

Nat Commun. 2016 May 4;7:11436. doi: 10.1038/ncomms11436.

31.

Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking.

Francavilla C, Papetti M, Rigbolt KT, Pedersen AK, Sigurdsson JO, Cazzamali G, Karemore G, Blagoev B, Olsen JV.

Nat Struct Mol Biol. 2016 Jun;23(6):608-18. doi: 10.1038/nsmb.3218. Epub 2016 May 2.

PMID:
27136326
32.

Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling.

Sedgwick GG, Larsen MS, Lischetti T, Streicher W, Jersie-Christensen RR, Olsen JV, Nilsson J.

MAbs. 2016 May-Jun;8(4):689-97. doi: 10.1080/19420862.2016.1160988. Epub 2016 Mar 17.

33.

Disulfide Linkage Characterization of Disulfide Bond-Containing Proteins and Peptides by Reducing Electrochemistry and Mass Spectrometry.

Cramer CN, Haselmann KF, Olsen JV, Nielsen PK.

Anal Chem. 2016 Feb 2;88(3):1585-92. doi: 10.1021/acs.analchem.5b03148. Epub 2016 Jan 8.

PMID:
26695097
34.

Systems Analysis for Interpretation of Phosphoproteomics Data.

Munk S, Refsgaard JC, Olsen JV.

Methods Mol Biol. 2016;1355:341-60. doi: 10.1007/978-1-4939-3049-4_23. Review.

PMID:
26584937
35.

From Phosphosites to Kinases.

Munk S, Refsgaard JC, Olsen JV, Jensen LJ.

Methods Mol Biol. 2016;1355:307-21. doi: 10.1007/978-1-4939-3049-4_21. Review.

PMID:
26584935
36.

Simple and Reproducible Sample Preparation for Single-Shot Phosphoproteomics with High Sensitivity.

Jersie-Christensen RR, Sultan A, Olsen JV.

Methods Mol Biol. 2016;1355:251-60. doi: 10.1007/978-1-4939-3049-4_17.

PMID:
26584931
37.

Offline High pH Reversed-Phase Peptide Fractionation for Deep Phosphoproteome Coverage.

Batth TS, Olsen JV.

Methods Mol Biol. 2016;1355:179-92. doi: 10.1007/978-1-4939-3049-4_12.

PMID:
26584926
38.

Protein kinase A stimulates Kv7.1 surface expression by regulating Nedd4-2-dependent endocytic trafficking.

Andersen MN, Hefting LL, Steffensen AB, Schmitt N, Olesen SP, Olsen JV, Lundby A, Rasmussen HB.

Am J Physiol Cell Physiol. 2015 Nov 15;309(10):C693-706. doi: 10.1152/ajpcell.00383.2014. Epub 2015 Sep 24.

39.

Recent findings and technological advances in phosphoproteomics for cells and tissues.

von Stechow L, Francavilla C, Olsen JV.

Expert Rev Proteomics. 2015;12(5):469-87. doi: 10.1586/14789450.2015.1078730. Review.

40.

Ubiquitin-specific Protease 11 (USP11) Deubiquitinates Hybrid Small Ubiquitin-like Modifier (SUMO)-Ubiquitin Chains to Counteract RING Finger Protein 4 (RNF4).

Hendriks IA, Schimmel J, Eifler K, Olsen JV, Vertegaal AC.

J Biol Chem. 2015 Jun 19;290(25):15526-37. doi: 10.1074/jbc.M114.618132. Epub 2015 May 12.

41.

Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation.

Emdal KB, Pedersen AK, Bekker-Jensen DB, Tsafou KP, Horn H, Lindner S, Schulte JH, Eggert A, Jensen LJ, Francavilla C, Olsen JV.

Sci Signal. 2015 Apr 28;8(374):ra40. doi: 10.1126/scisignal.2005769.

PMID:
25921289
42.

Ancient proteins resolve the evolutionary history of Darwin's South American ungulates.

Welker F, Collins MJ, Thomas JA, Wadsley M, Brace S, Cappellini E, Turvey ST, Reguero M, Gelfo JN, Kramarz A, Burger J, Thomas-Oates J, Ashford DA, Ashton PD, Rowsell K, Porter DM, Kessler B, Fischer R, Baessmann C, Kaspar S, Olsen JV, Kiley P, Elliott JA, Kelstrup CD, Mullin V, Hofreiter M, Willerslev E, Hublin JJ, Orlando L, Barnes I, MacPhee RD.

Nature. 2015 Jun 4;522(7554):81-4. doi: 10.1038/nature14249. Epub 2015 Mar 18.

PMID:
25799987
43.

SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage.

Hendriks IA, Treffers LW, Verlaan-de Vries M, Olsen JV, Vertegaal AC.

Cell Rep. 2015 Mar 10. pii: S2211-1247(15)00179-5. doi: 10.1016/j.celrep.2015.02.033. [Epub ahead of print]

44.

System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability.

Xiao Z, Chang JG, Hendriks IA, Sigurðsson JO, Olsen JV, Vertegaal AC.

Mol Cell Proteomics. 2015 May;14(5):1419-34. doi: 10.1074/mcp.O114.044792. Epub 2015 Mar 9.

45.

Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage.

Gibbs-Seymour I, Oka Y, Rajendra E, Weinert BT, Passmore LA, Patel KJ, Olsen JV, Choudhary C, Bekker-Jensen S, Mailand N.

Mol Cell. 2015 Jan 8;57(1):150-64. doi: 10.1016/j.molcel.2014.12.001. Epub 2014 Dec 31.

46.

Direct evidence of milk consumption from ancient human dental calculus.

Warinner C, Hendy J, Speller C, Cappellini E, Fischer R, Trachsel C, Arneborg J, Lynnerup N, Craig OE, Swallow DM, Fotakis A, Christensen RJ, Olsen JV, Liebert A, Montalva N, Fiddyment S, Charlton S, Mackie M, Canci A, Bouwman A, Rühli F, Gilbert MT, Collins MJ.

Sci Rep. 2014 Nov 27;4:7104. doi: 10.1038/srep07104.

47.

Ctk1 function is necessary for full translation initiation activity in Saccharomyces cerevisiae.

Coordes B, Brünger KM, Burger K, Soufi B, Horenk J, Eick D, Olsen JV, Sträßer K.

Eukaryot Cell. 2015 Jan;14(1):86-95. doi: 10.1128/EC.00106-14. Epub 2014 Nov 21.

48.

Rapid and deep proteomes by faster sequencing on a benchtop quadrupole ultra-high-field Orbitrap mass spectrometer.

Kelstrup CD, Jersie-Christensen RR, Batth TS, Arrey TN, Kuehn A, Kellmann M, Olsen JV.

J Proteome Res. 2014 Dec 5;13(12):6187-95. doi: 10.1021/pr500985w. Epub 2014 Nov 10.

PMID:
25349961
49.

Off-line high-pH reversed-phase fractionation for in-depth phosphoproteomics.

Batth TS, Francavilla C, Olsen JV.

J Proteome Res. 2014 Dec 5;13(12):6176-86. doi: 10.1021/pr500893m. Epub 2014 Nov 4.

PMID:
25338131
50.

Species identification of archaeological skin objects from Danish bogs: comparison between mass spectrometry-based peptide sequencing and microscopy-based methods.

Brandt LØ, Schmidt AL, Mannering U, Sarret M, Kelstrup CD, Olsen JV, Cappellini E.

PLoS One. 2014 Sep 26;9(9):e106875. doi: 10.1371/journal.pone.0106875. eCollection 2014.

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