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Items: 1 to 50 of 127

1.

Using prediction models to identify miRNA-based markers of low dose rate chronic stress.

Duale N, Eide DM, Amberger ML, Graupner A, Brede DA, Olsen AK.

Sci Total Environ. 2020 May 15;717:137068. doi: 10.1016/j.scitotenv.2020.137068. Epub 2020 Feb 4.

2.

Corrigendum to: Standardisation of the in vitro comet assay: influence of lysis time and lysis solution composition on the detection of DNA damage induced by X-rays.

Enciso JM, Gutzkow KB, Brunborg G, Olsen AK, de Cerain AL, Azqueta A.

Mutagenesis. 2019 Dec 19;34(5-6):431. doi: 10.1093/mutage/gez036. No abstract available.

PMID:
31858151
3.

Intestinal regulation of suppression of tumorigenicity 14 (ST14) and serine peptidase inhibitor, Kunitz type -1 (SPINT1) by transcription factor CDX2.

Danielsen ET, Olsen AK, Coskun M, Nonboe AW, Larsen S, Dahlgaard K, Bennett EP, Mitchelmore C, Vogel LK, Troelsen JT.

Sci Rep. 2018 Aug 7;8(1):11813. doi: 10.1038/s41598-018-30216-z.

4.

Ionizing radiation does not impair the mechanisms controlling genetic stability during T cell receptor gene rearrangement in mice.

Candéias SM, Kabacik S, Olsen AK, Eide DM, Brede DA, Bouffler S, Badie C.

Int J Radiat Biol. 2018 Apr;94(4):357-365. doi: 10.1080/09553002.2018.1439195. Epub 2018 Feb 27.

PMID:
29431562
5.

Standardisation of the in vitro comet assay: influence of lysis time and lysis solution composition on the detection of DNA damage induced by X-rays.

Enciso JM, Gutzkow KB, Brunborg G, Olsen AK, López de Cerain A, Azqueta A.

Mutagenesis. 2018 Feb 24;33(1):25-30. doi: 10.1093/mutage/gex039.

PMID:
29329446
6.

Using the comet assay and lysis conditions to characterize DNA lesions from the acrylamide metabolite glycidamide.

Hansen SH, Pawlowicz AJ, Kronberg L, Gützkow KB, Olsen AK, Brunborg G.

Mutagenesis. 2018 Feb 24;33(1):31-39. doi: 10.1093/mutage/gex036.

PMID:
29240951
7.

Paternal Exposure to Environmental Chemical Stress Affects Male Offspring's Hepatic Mitochondria.

Godschalk R, Remels A, Hoogendoorn C, van Benthem J, Luijten M, Duale N, Brunborg G, Olsen AK, Bouwman FG, Munnia A, Peluso M, Mariman E, van Schooten FJ.

Toxicol Sci. 2018 Mar 1;162(1):241-250. doi: 10.1093/toxsci/kfx246.

PMID:
29145655
8.

Restoration of Cognitive Performance in Mice Carrying a Deficient Allele of 8-Oxoguanine DNA Glycosylase by X-ray Irradiation.

Hofer T, Duale N, Muusse M, Eide DM, Dahl H, Boix F, Andersen JM, Olsen AK, Myhre O.

Neurotox Res. 2018 May;33(4):824-836. doi: 10.1007/s12640-017-9833-7. Epub 2017 Nov 3.

PMID:
29101721
9.

Parental gamma irradiation induces reprotoxic effects accompanied by genomic instability in zebrafish (Danio rerio) embryos.

Hurem S, Gomes T, Brede DA, Lindbo Hansen E, Mutoloki S, Fernandez C, Mothersill C, Salbu B, Kassaye YA, Olsen AK, Oughton D, Aleström P, Lyche JL.

Environ Res. 2017 Nov;159:564-578. doi: 10.1016/j.envres.2017.07.053. Epub 2017 Sep 9.

PMID:
28892785
10.

Genotoxic effects of high dose rate X-ray and low dose rate gamma radiation in ApcMin/+ mice.

Graupner A, Eide DM, Brede DA, Ellender M, Lindbo Hansen E, Oughton DH, Bouffler SD, Brunborg G, Olsen AK.

Environ Mol Mutagen. 2017 Oct;58(8):560-569. doi: 10.1002/em.22121. Epub 2017 Aug 30.

11.

No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice.

Rolseth V, Luna L, Olsen AK, Suganthan R, Scheffler K, Neurauter CG, Esbensen Y, Kuśnierczyk A, Hildrestrand GA, Graupner A, Andersen JM, Slupphaug G, Klungland A, Nilsen H, Bjørås M.

Sci Rep. 2017 Jun 29;7(1):4384. doi: 10.1038/s41598-017-04472-4.

12.

The Pig-a Gene Mutation Assay in Mice and Human Cells: A Review.

Olsen AK, Dertinger SD, Krüger CT, Eide DM, Instanes C, Brunborg G, Hartwig A, Graupner A.

Basic Clin Pharmacol Toxicol. 2017 Sep;121 Suppl 3:78-92. doi: 10.1111/bcpt.12806. Epub 2017 Jun 19. Review.

13.

Corrigendum: Reference cells and ploidy in the comet assay.

Brunborg G, Collins A, Graupner A, Gutzkow KB, Olsen AK.

Front Genet. 2017 Jan 24;8:4. doi: 10.3389/fgene.2017.00004. eCollection 2017.

14.

In Vitro Functional Analyses of Infrequent Nucleotide Variants in the Lactase Enhancer Reveal Different Molecular Routes to Increased Lactase Promoter Activity and Lactase Persistence.

Liebert A, Jones BL, Danielsen ET, Olsen AK, Swallow DM, Troelsen JT.

Ann Hum Genet. 2016 Nov;80(6):307-318. doi: 10.1111/ahg.12167. Epub 2016 Oct 7.

15.

Gamma radiation at a human relevant low dose rate is genotoxic in mice.

Graupner A, Eide DM, Instanes C, Andersen JM, Brede DA, Dertinger SD, Lind OC, Brandt-Kjelsen A, Bjerke H, Salbu B, Oughton D, Brunborg G, Olsen AK.

Sci Rep. 2016 Sep 6;6:32977. doi: 10.1038/srep32977.

16.

Enhanced susceptibility of obese mice to glycidamide-induced sperm chromatin damage without increased oxidative stress.

Gutzkow KB, Duale N, Danielsen T, von Stedingk H, Shahzadi S, Instanes C, Olsen AK, Steffensen IL, Hofer T, Törnqvist M, Brunborg G, Lindeman B.

Andrology. 2016 Nov;4(6):1102-1114. doi: 10.1111/andr.12233. Epub 2016 Aug 30.

17.

Genotoxicity and gene expression modulation of silver and titanium dioxide nanoparticles in mice.

Asare N, Duale N, Slagsvold HH, Lindeman B, Olsen AK, Gromadzka-Ostrowska J, Meczynska-Wielgosz S, Kruszewski M, Brunborg G, Instanes C.

Nanotoxicology. 2016;10(3):312-21. doi: 10.3109/17435390.2015.1071443. Epub 2015 Aug 17.

PMID:
26923343
18.

Liraglutide in Type 2 Diabetes Mellitus: Clinical Pharmacokinetics and Pharmacodynamics.

Jacobsen LV, Flint A, Olsen AK, Ingwersen SH.

Clin Pharmacokinet. 2016 Jun;55(6):657-72. doi: 10.1007/s40262-015-0343-6. Review.

19.

Causes of genome instability: the effect of low dose chemical exposures in modern society.

Langie SA, Koppen G, Desaulniers D, Al-Mulla F, Al-Temaimi R, Amedei A, Azqueta A, Bisson WH, Brown DG, Brunborg G, Charles AK, Chen T, Colacci A, Darroudi F, Forte S, Gonzalez L, Hamid RA, Knudsen LE, Leyns L, Lopez de Cerain Salsamendi A, Memeo L, Mondello C, Mothersill C, Olsen AK, Pavanello S, Raju J, Rojas E, Roy R, Ryan EP, Ostrosky-Wegman P, Salem HK, Scovassi AI, Singh N, Vaccari M, Van Schooten FJ, Valverde M, Woodrick J, Zhang L, van Larebeke N, Kirsch-Volders M, Collins AR.

Carcinogenesis. 2015 Jun;36 Suppl 1:S61-88. doi: 10.1093/carcin/bgv031. Review.

20.

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Goodson WH 3rd, Lowe L, Carpenter DO, Gilbertson M, Manaf Ali A, Lopez de Cerain Salsamendi A, Lasfar A, Carnero A, Azqueta A, Amedei A, Charles AK, Collins AR, Ward A, Salzberg AC, Colacci A, Olsen AK, Berg A, Barclay BJ, Zhou BP, Blanco-Aparicio C, Baglole CJ, Dong C, Mondello C, Hsu CW, Naus CC, Yedjou C, Curran CS, Laird DW, Koch DC, Carlin DJ, Felsher DW, Roy D, Brown DG, Ratovitski E, Ryan EP, Corsini E, Rojas E, Moon EY, Laconi E, Marongiu F, Al-Mulla F, Chiaradonna F, Darroudi F, Martin FL, Van Schooten FJ, Goldberg GS, Wagemaker G, Nangami GN, Calaf GM, Williams G, Wolf GT, Koppen G, Brunborg G, Lyerly HK, Krishnan H, Ab Hamid H, Yasaei H, Sone H, Kondoh H, Salem HK, Hsu HY, Park HH, Koturbash I, Miousse IR, Scovassi AI, Klaunig JE, Vondráček J, Raju J, Roman J, Wise JP Sr, Whitfield JR, Woodrick J, Christopher JA, Ochieng J, Martinez-Leal JF, Weisz J, Kravchenko J, Sun J, Prudhomme KR, Narayanan KB, Cohen-Solal KA, Moorwood K, Gonzalez L, Soucek L, Jian L, D'Abronzo LS, Lin LT, Li L, Gulliver L, McCawley LJ, Memeo L, Vermeulen L, Leyns L, Zhang L, Valverde M, Khatami M, Romano MF, Chapellier M, Williams MA, Wade M, Manjili MH, Lleonart ME, Xia M, Gonzalez MJ, Karamouzis MV, Kirsch-Volders M, Vaccari M, Kuemmerle NB, Singh N, Cruickshanks N, Kleinstreuer N, van Larebeke N, Ahmed N, Ogunkua O, Krishnakumar PK, Vadgama P, Marignani PA, Ghosh PM, Ostrosky-Wegman P, Thompson PA, Dent P, Heneberg P, Darbre P, Sing Leung P, Nangia-Makker P, Cheng QS, Robey RB, Al-Temaimi R, Roy R, Andrade-Vieira R, Sinha RK, Mehta R, Vento R, Di Fiore R, Ponce-Cusi R, Dornetshuber-Fleiss R, Nahta R, Castellino RC, Palorini R, Abd Hamid R, Langie SA, Eltom SE, Brooks SA, Ryeom S, Wise SS, Bay SN, Harris SA, Papagerakis S, Romano S, Pavanello S, Eriksson S, Forte S, Casey SC, Luanpitpong S, Lee TJ, Otsuki T, Chen T, Massfelder T, Sanderson T, Guarnieri T, Hultman T, Dormoy V, Odero-Marah V, Sabbisetti V, Maguer-Satta V, Rathmell WK, Engström W, Decker WK, Bisson WH, Rojanasakul Y, Luqmani Y, Chen Z, Hu Z.

Carcinogenesis. 2015 Jun;36 Suppl 1:S254-96. doi: 10.1093/carcin/bgv039. Review. Erratum in: Carcinogenesis. 2016 Mar;37(3):344.

21.

Nickel-catalyzed reductive arylation of activated alkynes with aryl iodides.

Dorn SC, Olsen AK, Kelemen RE, Shrestha R, Weix DJ.

Tetrahedron Lett. 2015 Jun 3;56(23):3365-3367.

22.

Transcending differences to study the transcendent: an exploratory study of researchers' and chaplains' reflections on interdisciplinary spiritual care research collaboration.

Powell RA, Emanuel L, Handzo G, Lantos J, Dunn LB, Idler EL, Wilkie DJ, Massey K, Summerfelt WT, Barnes MJ, Quest TE, Kestenbaum A, Steinhauser K, Fitchett G, Zollfrank A, Olsen AK, Balboni TA, Sommer D.

BMC Palliat Care. 2015 Apr 18;14:12. doi: 10.1186/s12904-015-0004-4.

23.

Reference cells and ploidy in the comet assay.

Brunborg G, Collins A, Graupner A, Gutzkow KB, Olsen AK.

Front Genet. 2015 Feb 27;6:61. doi: 10.3389/fgene.2015.00061. eCollection 2015. Erratum in: Front Genet. 2017 Jan 24;8:4.

24.

Genotoxic effects of two-generational selenium deficiency in mouse somatic and testicular cells.

Graupner A, Instanes C, Andersen JM, Brandt-Kjelsen A, Dertinger SD, Salbu B, Brunborg G, Olsen AK.

Mutagenesis. 2015 Mar;30(2):217-25. doi: 10.1093/mutage/geu059. Epub 2014 Oct 30.

25.

Single cell gel electrophoresis (SCGE) and Pig-a mutation assay in vivo-tools for genotoxicity testing from a regulatory perspective: a study of benzo[a]pyrene in Ogg1(-/-) mice.

Graupner A, Instanes C, Dertinger SD, Andersen JM, Lindeman B, Rongved TD, Brunborg G, Olsen AK.

Mutat Res Genet Toxicol Environ Mutagen. 2014 Sep 15;772:34-41. doi: 10.1016/j.mrgentox.2014.07.010. Epub 2014 Aug 7.

26.

Involvement of CDX2 in the cross talk between TNF-α and Wnt signaling pathway in the colon cancer cell line Caco-2.

Coskun M, Olsen AK, Bzorek M, Holck S, Engel UH, Nielsen OH, Troelsen JT.

Carcinogenesis. 2014 May;35(5):1185-92. doi: 10.1093/carcin/bgu037. Epub 2014 Feb 5.

PMID:
24501326
27.

Diversity of lactase persistence alleles in Ethiopia: signature of a soft selective sweep.

Jones BL, Raga TO, Liebert A, Zmarz P, Bekele E, Danielsen ET, Olsen AK, Bradman N, Troelsen JT, Swallow DM.

Am J Hum Genet. 2013 Sep 5;93(3):538-44. doi: 10.1016/j.ajhg.2013.07.008. Epub 2013 Aug 29.

28.

Paternal lifestyle as a potential source of germline mutations transmitted to offspring.

Linschooten JO, Verhofstad N, Gutzkow K, Olsen AK, Yauk C, Oligschläger Y, Brunborg G, van Schooten FJ, Godschalk RW.

FASEB J. 2013 Jul;27(7):2873-9. doi: 10.1096/fj.13-227694. Epub 2013 Mar 28.

29.

Regulation of APC and AXIN2 expression by intestinal tumor suppressor CDX2 in colon cancer cells.

Olsen AK, Coskun M, Bzorek M, Kristensen MH, Danielsen ET, Jørgensen S, Olsen J, Engel U, Holck S, Troelsen JT.

Carcinogenesis. 2013 Jun;34(6):1361-9. doi: 10.1093/carcin/bgt037. Epub 2013 Feb 7.

PMID:
23393221
30.

Paternal benzo[a]pyrene exposure affects gene expression in the early developing mouse embryo.

Brevik A, Lindeman B, Rusnakova V, Olsen AK, Brunborg G, Duale N.

Toxicol Sci. 2012 Sep;129(1):157-65. doi: 10.1093/toxsci/kfs187. Epub 2012 May 28.

31.

TNF-α-induced down-regulation of CDX2 suppresses MEP1A expression in colitis.

Coskun M, Olsen AK, Holm TL, Kvist PH, Nielsen OH, Riis LB, Olsen J, Troelsen JT.

Biochim Biophys Acta. 2012 Jun;1822(6):843-51. doi: 10.1016/j.bbadis.2012.01.012. Epub 2012 Feb 3.

32.

Current and emerging approaches to define intestinal epithelium-specific transcriptional networks.

Olsen AK, Boyd M, Danielsen ET, Troelsen JT.

Am J Physiol Gastrointest Liver Physiol. 2012 Feb 1;302(3):G277-86. doi: 10.1152/ajpgi.00362.2011. Epub 2011 Nov 17. Review.

33.

Preconceptional paternal glycidamide exposure affects embryonic gene expression: single embryo gene expression study following in vitro fertilization.

Brevik A, Rusnakova V, Duale N, Slagsvold HH, Olsen AK, Storeng R, Kubista M, Brunborg G, Lindeman B.

Reprod Toxicol. 2011 Dec;32(4):463-71. doi: 10.1016/j.reprotox.2011.09.005. Epub 2011 Sep 29.

PMID:
21978862
34.

Spermatogenesis is not impaired in a nucleotide excision repair-deficient min mouse model with or without neonatal mutagen treatment.

Andreassen A, Steffensen IL, Olsen AK, Tanaka K, Wiger R.

J Androl. 2011 Sep-Oct;32(5):541-9. doi: 10.2164/jandrol.110.011916. Epub 2011 Jan 13.

PMID:
21233395
35.

Metabolism and excretion of the once-daily human glucagon-like peptide-1 analog liraglutide in healthy male subjects and its in vitro degradation by dipeptidyl peptidase IV and neutral endopeptidase.

Malm-Erjefält M, Bjørnsdottir I, Vanggaard J, Helleberg H, Larsen U, Oosterhuis B, van Lier JJ, Zdravkovic M, Olsen AK.

Drug Metab Dispos. 2010 Nov;38(11):1944-53. doi: 10.1124/dmd.110.034066. Epub 2010 Aug 13.

PMID:
20709939
36.

Environmental exposure of the mouse germ line: DNA adducts in spermatozoa and formation of de novo mutations during spermatogenesis.

Olsen AK, Andreassen A, Singh R, Wiger R, Duale N, Farmer PB, Brunborg G.

PLoS One. 2010 Jun 28;5(6):e11349. doi: 10.1371/journal.pone.0011349.

37.

Genome-wide analysis of CDX2 binding in intestinal epithelial cells (Caco-2).

Boyd M, Hansen M, Jensen TG, Perearnau A, Olsen AK, Bram LL, Bak M, Tommerup N, Olsen J, Troelsen JT.

J Biol Chem. 2010 Aug 13;285(33):25115-25. doi: 10.1074/jbc.M109.089516. Epub 2010 Jun 15.

38.

Octyl methoxycinnamate modulates gene expression and prevents cyclobutane pyrimidine dimer formation but not oxidative DNA damage in UV-exposed human cell lines.

Duale N, Olsen AK, Christensen T, Butt ST, Brunborg G.

Toxicol Sci. 2010 Apr;114(2):272-84. doi: 10.1093/toxsci/kfq005. Epub 2010 Jan 13.

39.

In vitro investigations of glycidamide-induced DNA lesions in mouse male germ cells and in mouse and human lymphocytes.

Hansen SH, Olsen AK, Søderlund EJ, Brunborg G.

Mutat Res. 2010 Feb;696(1):55-61. doi: 10.1016/j.mrgentox.2009.12.012. Epub 2009 Dec 22.

PMID:
20026424
40.
41.

ISSLS prize winner: positron emission tomography and magnetic resonance imaging for monitoring interbody fusion with equine bone protein extract, recombinant human bone morphogenetic protein-2, and autograft.

Foldager C, Bendtsen M, Zou X, Zou L, Olsen AK, Munk OL, Stødkilde-Jørgensen H, Bünger C.

Spine (Phila Pa 1976). 2008 Dec 1;33(25):2683-90. doi: 10.1097/BRS.0b013e31817fce91.

PMID:
19002076
42.

Guiding principles of safety as a basis for developing a pharmaceutical safety culture.

Edwards B, Olsen AK, Whalen MD, Gold MJ.

Curr Drug Saf. 2007 May;2(2):135-9. Review.

PMID:
18690959
43.

Hepatic uptake and metabolism of galactose can be quantified in vivo by 2-[18F]fluoro-2-deoxygalactose positron emission tomography.

Sørensen M, Munk OL, Mortensen FV, Olsen AK, Bender D, Bass L, Keiding S.

Am J Physiol Gastrointest Liver Physiol. 2008 Jul;295(1):G27-G36. doi: 10.1152/ajpgi.00004.2008. Epub 2008 May 15.

44.

Synthesis and cerebral uptake of 1-(1-[(11)C]methyl-1H-pyrrol-2-yl)-2-phenyl-2-(1-pyrrolidinyl)ethanone, a novel tracer for positron emission tomography studies of monoamine oxidase type A.

Jensen SB, Di Santo R, Olsen AK, Pedersen K, Costi R, Cirilli R, Cumming P.

J Med Chem. 2008 Mar 27;51(6):1617-22. doi: 10.1021/jm701378e. Epub 2008 Feb 29.

PMID:
18307289
45.

Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profiles.

Duale N, Lindeman B, Komada M, Olsen AK, Andreassen A, Soderlund EJ, Brunborg G.

Mol Cancer. 2007 Aug 21;6:53.

46.

Effects of organohalogen pollutants on haematological and urine clinical-chemical parameters in Greenland sledge dogs (Canis familiaris).

Sonne C, Dietz R, Kirkegaard M, Letcher RJ, Shahmiri S, Andersen S, Møller P, Olsen AK, Jensen AL.

Ecotoxicol Environ Saf. 2008 Mar;69(3):381-90. Epub 2007 Apr 16.

PMID:
17434585
47.

A PET study of effects of chronic 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on serotonin markers in Göttingen minipig brain.

Cumming P, Møller M, Benda K, Minuzzi L, Jakobsen S, Jensen SB, Pakkenberg B, Stark AK, Gramsbergen JB, Andreasen MF, Olsen AK.

Synapse. 2007 Jul;61(7):478-87.

PMID:
17415793
48.

Mapping the amphetamine-evoked changes in [11C]raclopride binding in living rat using small animal PET: modulation by MAO-inhibition.

Pedersen K, Simonsen M, Østergaard SD, Munk OL, Rosa-Neto P, Olsen AK, Jensen SB, Møller A, Cumming P.

Neuroimage. 2007 Mar;35(1):38-46. Epub 2007 Jan 16.

PMID:
17223363
49.
50.

Anabolic and catabolic function of chondrocyte ex vivo is reflected by the metabolic processing of type II collagen.

Olsen AK, Sondergaard BC, Byrjalsen I, Tanko LB, Christiansen C, Müller A, Hein GE, Karsdal MA, Qvist P.

Osteoarthritis Cartilage. 2007 Mar;15(3):335-42. Epub 2006 Oct 11.

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