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Items: 1 to 50 of 265

1.

Mildly increased pulmonary arterial pressure: a new disease entity or just a marker of poor prognosis?

Kovacs G, Douschan P, Maron BA, Condliffe R, Olschewski H.

Eur J Heart Fail. 2019 Aug 13. doi: 10.1002/ejhf.1570. [Epub ahead of print] No abstract available.

PMID:
31407852
2.

IL-1 receptor blockade skews inflammation towards Th2 in a mouse model of systemic sclerosis.

Gungl A, Crnkovic S, Biasin V, Marsh LM, Odler B, Sahu-Osen A, Stacher-Priehse E, Brcic L, Schneider F, Cikes N, Ghanim B, Klepetko W, Graninger W, Allanore Y, Eferl R, Olschewski A, Olschewski H, Kwapiszewska G.

Eur Respir J. 2019 Jul 18. pii: 1900154. doi: 10.1183/13993003.00154-2019. [Epub ahead of print]

PMID:
31320452
3.

Pulmonary and cardiac drugs: clinically relevant interactions.

Olschewski H, Canepa M, Kovacs G.

Herz. 2019 Jul 11. doi: 10.1007/s00059-019-4834-3. [Epub ahead of print]

PMID:
31297545
4.

[Hemodynamic Definition of Pulmonary Hypertension: Commentary on the Proposed Change by the 6th World Symposium on Pulmonary Hypertension].

Rosenkranz S, Diller GP, Dumitrescu D, Ewert R, Ghofrani HA, Grünig E, Halank M, Held M, Kaemmerer H, Klose H, Kovacs G, Konstantinides S, Lang IM, Lange TJ, Leuchte H, Mayer E, Olschewski A, Olschewski H, Olsson KM, Opitz C, Schermuly RT, Seeger W, Wilkens H, Hoeper MM.

Dtsch Med Wochenschr. 2019 Jul 5. doi: 10.1055/a-0918-3772. [Epub ahead of print] German.

5.

Gluconeogenesis in cancer cells - Repurposing of a starvation-induced metabolic pathway?

Grasmann G, Smolle E, Olschewski H, Leithner K.

Biochim Biophys Acta Rev Cancer. 2019 Aug;1872(1):24-36. doi: 10.1016/j.bbcan.2019.05.006. Epub 2019 May 30. Review.

6.

Targeting TMEM16A to reverse vasoconstriction and remodelling in idiopathic pulmonary arterial hypertension.

Papp R, Nagaraj C, Zabini D, Nagy BM, Lengyel M, Skofic Maurer D, Sharma N, Egemnazarov B, Kovacs G, Kwapiszewska G, Marsh LM, Hrzenjak A, Höfler G, Didiasova M, Wygrecka M, Sievers LK, Szucs P, Enyedi P, Ghanim B, Klepetko W, Olschewski H, Olschewski A.

Eur Respir J. 2019 Jun 5;53(6). pii: 1800965. doi: 10.1183/13993003.00965-2018. Print 2019 Jun.

PMID:
31023847
7.

The pulmonary haemodynamics during exercise - research network (PEX-NET) ERS Clinical Research Collaboration: investigating the prognostic relevance of exercise haemodynamics.

Kovacs G, Herve P, Olschewski H; PEX-NET Clinical Research Collaboration.

Eur Respir J. 2019 Apr 11;53(4). pii: 1900458. doi: 10.1183/13993003.00458-2019. Print 2019 Apr. No abstract available.

PMID:
30975765
8.

Take your drug and climb Machu Picchu!

Kovacs G, Olschewski H.

Int J Cardiol. 2019 Aug 1;288:135-136. doi: 10.1016/j.ijcard.2019.02.053. Epub 2019 Feb 28. No abstract available.

PMID:
30890273
9.

EXPRESS: Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI).

Kiely DG, Levin D, Hassoun P, Ivy DD, Jone PN, Bwika J, Kawut SM, Lordan J, Lungu A, Mazurek J, Moledina S, Olschewski H, Peacock A, Puri GD, Rahaghi F, Schafer M, Schiebler M, Screaton N, Tawhai M, Van Beek EJ, Vonk-Noordegraaf A, Vanderpool RR, Wort J, Zhao L, Wild J, Vogel-Claussen J, Swift AJ.

Pulm Circ. 2019 Mar 18:2045894019841990. doi: 10.1177/2045894019841990. [Epub ahead of print] No abstract available.

10.

Quantitative CT-derived vessel metrics in idiopathic pulmonary fibrosis: A structure-function study.

Jacob J, Pienn M, Payer C, Urschler M, Kokosi M, Devaraj A, Wells AU, Olschewski H.

Respirology. 2019 May;24(5):445-452. doi: 10.1111/resp.13485. Epub 2019 Feb 20.

11.

Advanced interstitial lung fibrosis with emphysema and pulmonary hypertension with no evidence for interstitial lung disease on high resolution CT.

Foris V, Brcic L, Douschan P, Kovacs G, Stacher-Priehse E, Olschewski H.

Pulm Circ. 2019 Jul-Sep;9(3):2045894019832214. doi: 10.1177/2045894019832214.

12.

ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension.

Grünig E, Eichstaedt C, Barberà JA, Benjamin N, Blanco I, Bossone E, Cittadini A, Coghlan G, Corris P, D'Alto M, D'Andrea A, Delcroix M, de Man F, Gaine S, Ghio S, Gibbs S, Gumbiene L, Howard LS, Johnson M, Jurevičienė E, Kiely DG, Kovacs G, MacKenzie A, Marra AM, McCaffrey N, McCaughey P, Naeije R, Olschewski H, Pepke-Zaba J, Reis A, Santos M, Saxer S, Tulloh RM, Ulrich S, Vonk Noordegraaf A, Peacock AJ.

Eur Respir J. 2019 Feb 28;53(2). pii: 1800332. doi: 10.1183/13993003.00332-2018. Print 2019 Feb.

PMID:
30578391
13.

Disconnect between Fibrotic Response and Right Ventricular Dysfunction.

Crnkovic S, Egemnazarov B, Damico R, Marsh LM, Nagy BM, Douschan P, Atsina K, Kolb TM, Mathai SC, Hooper JE, Ghanim B, Klepetko W, Fruhwald F, Lassner D, Olschewski A, Olschewski H, Hassoun PM, Kwapiszewska G.

Am J Respir Crit Care Med. 2019 Jun 15;199(12):1550-1560. doi: 10.1164/rccm.201809-1737OC.

PMID:
30557518
14.

Pulmonary hypertension in chronic lung disease and hypoxia.

Nathan SD, Barbera JA, Gaine SP, Harari S, Martinez FJ, Olschewski H, Olsson KM, Peacock AJ, Pepke-Zaba J, Provencher S, Weissmann N, Seeger W.

Eur Respir J. 2019 Jan 24;53(1). pii: 1801914. doi: 10.1183/13993003.01914-2018. Print 2019 Jan.

15.

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Rhodes CJ, Batai K, Bleda M, Haimel M, Southgate L, Germain M, Pauciulo MW, Hadinnapola C, Aman J, Girerd B, Arora A, Knight J, Hanscombe KB, Karnes JH, Kaakinen M, Gall H, Ulrich A, Harbaum L, Cebola I, Ferrer J, Lutz K, Swietlik EM, Ahmad F, Amouyel P, Archer SL, Argula R, Austin ED, Badesch D, Bakshi S, Barnett C, Benza R, Bhatt N, Bogaard HJ, Burger CD, Chakinala M, Church C, Coghlan JG, Condliffe R, Corris PA, Danesino C, Debette S, Elliott CG, Elwing J, Eyries M, Fortin T, Franke A, Frantz RP, Frost A, Garcia JGN, Ghio S, Ghofrani HA, Gibbs JSR, Harley J, He H, Hill NS, Hirsch R, Houweling AC, Howard LS, Ivy D, Kiely DG, Klinger J, Kovacs G, Lahm T, Laudes M, Machado RD, MacKenzie Ross RV, Marsolo K, Martin LJ, Moledina S, Montani D, Nathan SD, Newnham M, Olschewski A, Olschewski H, Oudiz RJ, Ouwehand WH, Peacock AJ, Pepke-Zaba J, Rehman Z, Robbins I, Roden DM, Rosenzweig EB, Saydain G, Scelsi L, Schilz R, Seeger W, Shaffer CM, Simms RW, Simon M, Sitbon O, Suntharalingam J, Tang H, Tchourbanov AY, Thenappan T, Torres F, Toshner MR, Treacy CM, Vonk Noordegraaf A, Waisfisz Q, Walsworth AK, Walter RE, Wharton J, White RJ, Wilt J, Wort SJ, Yung D, Lawrie A, Humbert M, Soubrier F, Trégouët DA, Prokopenko I, Kittles R, Gräf S, Nichols WC, Trembath RC, Desai AA, Morrell NW, Wilkins MR; UK NIHR BioResource Rare Diseases Consortium; UK PAH Cohort Study Consortium; US PAH Biobank Consortium.

Lancet Respir Med. 2019 Mar;7(3):227-238. doi: 10.1016/S2213-2600(18)30409-0. Epub 2018 Dec 5.

16.

Long non-coding RNAs influence the transcriptome in pulmonary arterial hypertension: the role of PAXIP1-AS1.

Jandl K, Thekkekara Puthenparampil H, Marsh LM, Hoffmann J, Wilhelm J, Veith C, Sinn K, Klepetko W, Olschewski H, Olschewski A, Brock M, Kwapiszewska G.

J Pathol. 2019 Mar;247(3):357-370. doi: 10.1002/path.5195. Epub 2019 Jan 16.

PMID:
30450722
17.

Crackle and Breathing Phase Detection in Lung Sounds with Deep Bidirectional Gated Recurrent Neural Networks.

Messner E, Fediuk M, Swatek P, Scheidl S, Smolle-Juttner FM, Olschewski H, Pernkopf F.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:356-359. doi: 10.1109/EMBC.2018.8512237.

PMID:
30440410
18.

Imatinib for right heart failure in COPD.

Douschan P, Kovacs G, Foris V, Kuehnelt-Leddihn M, Olschewski H.

Pulm Circ. 2019 Jan-Mar;9(1):2045894018816974. doi: 10.1177/2045894018816974. Epub 2018 Nov 15.

19.

Cologne consensus conference on pulmonary hypertension - Update 2018.

Rosenkranz S, Ghofrani HA, Grünig E, Klose H, Olschewski H, Hoeper MM.

Int J Cardiol. 2018 Dec 1;272S:1-3. doi: 10.1016/j.ijcard.2018.09.064. Epub 2018 Sep 22. No abstract available.

PMID:
30344062
20.

Clinical-Pathological Conference Series from the Medical University of Graz : Case No 168: A 28-year-old Syrian refugee with severe abdominal pain and eosinophilia.

Fabian E, Auer H, Kump P, Krause R, Wagner M, Fuchsjäger M, Janek E, Olschewski H, Krejs GJ.

Wien Klin Wochenschr. 2018 Oct;130(19-20):581-588. doi: 10.1007/s00508-018-1395-z. Epub 2018 Oct 15. No abstract available.

21.

Are anticoagulants still indicated in pulmonary arterial hypertension?

Olschewski H, Rich S.

Pulm Circ. 2018 Oct-Dec;8(4):2045894018807681. doi: 10.1177/2045894018807681. Epub 2018 Oct 4.

22.

Advancing into the details of pulmonary haemodynamics during exercise.

Kovacs G, Olschewski H.

Eur Respir J. 2018 Sep 17;52(3). pii: 1801578. doi: 10.1183/13993003.01578-2018. Print 2018 Sep. No abstract available.

PMID:
30224546
23.

Transcriptome profiling reveals the complexity of pirfenidone effects in idiopathic pulmonary fibrosis.

Kwapiszewska G, Gungl A, Wilhelm J, Marsh LM, Thekkekara Puthenparampil H, Sinn K, Didiasova M, Klepetko W, Kosanovic D, Schermuly RT, Wujak L, Weiss B, Schaefer L, Schneider M, Kreuter M, Olschewski A, Seeger W, Olschewski H, Wygrecka M.

Eur Respir J. 2018 Nov 22;52(5). pii: 1800564. doi: 10.1183/13993003.00564-2018. Print 2018 Nov.

24.

Pulmonary hypertension due to lung diseases: Updated recommendations from the Cologne Consensus Conference 2018.

Olschewski H, Behr J, Bremer H, Claussen M, Douschan P, Halank M, Held M, Hoeper MM, Holt S, Klose H, Krüger S, Lange TJ, Reichenberger F, Skowasch D, Ulrich S, Wilkens H, Seeger W.

Int J Cardiol. 2018 Dec 1;272S:63-68. doi: 10.1016/j.ijcard.2018.08.043. Epub 2018 Aug 11. Review.

PMID:
30131231
25.

Whole-Body Lung Function Test-Derived Outcome Predictors in Allogenic Stem Cell Transplantation.

Scheidl S, Zinke-Cerwenka W, Flick H, Gaal S, Avian A, Greinix H, Olschewski H.

Biol Blood Marrow Transplant. 2019 Jan;25(1):129-136. doi: 10.1016/j.bbmt.2018.07.036. Epub 2018 Jul 29.

PMID:
30064013
26.

Should patients with pulmonary hypertension fly and climb?

Kovacs G, Olschewski H.

Int J Cardiol. 2018 Nov 1;270:276-277. doi: 10.1016/j.ijcard.2018.07.054. Epub 2018 Jul 12. No abstract available.

PMID:
30031623
27.

Biomarkers for Pulmonary Vascular Remodeling in Systemic Sclerosis: A Pathophysiological Approach.

Odler B, Foris V, Gungl A, Müller V, Hassoun PM, Kwapiszewska G, Olschewski H, Kovacs G.

Front Physiol. 2018 Jun 19;9:587. doi: 10.3389/fphys.2018.00587. eCollection 2018. Review.

28.

Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.

Fazakas C, Nagaraj C, Zabini D, Végh AG, Marsh LM, Wilhelm I, Krizbai IA, Olschewski H, Olschewski A, Bálint Z.

Front Physiol. 2018 May 15;9:537. doi: 10.3389/fphys.2018.00537. eCollection 2018.

29.

The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells.

Leithner K, Triebl A, Trötzmüller M, Hinteregger B, Leko P, Wieser BI, Grasmann G, Bertsch AL, Züllig T, Stacher E, Valli A, Prassl R, Olschewski A, Harris AL, Köfeler HC, Olschewski H, Hrzenjak A.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6225-6230. doi: 10.1073/pnas.1719871115. Epub 2018 May 29.

30.

Healthy Lung Vessel Morphology Derived From Thoracic Computed Tomography.

Pienn M, Burgard C, Payer C, Avian A, Urschler M, Stollberger R, Olschewski A, Olschewski H, Johnson T, Meinel FG, Bálint Z.

Front Physiol. 2018 Apr 10;9:346. doi: 10.3389/fphys.2018.00346. eCollection 2018.

31.

Pulmonary Vascular Involvement in Chronic Obstructive Pulmonary Disease. Is There a Pulmonary Vascular Phenotype?

Kovacs G, Agusti A, Barberà JA, Celli B, Criner G, Humbert M, Sin DD, Voelkel N, Olschewski H.

Am J Respir Crit Care Med. 2018 Oct 15;198(8):1000-1011. doi: 10.1164/rccm.201801-0095PP. No abstract available.

PMID:
29746142
32.

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension.

Gräf S, Haimel M, Bleda M, Hadinnapola C, Southgate L, Li W, Hodgson J, Liu B, Salmon RM, Southwood M, Machado RD, Martin JM, Treacy CM, Yates K, Daugherty LC, Shamardina O, Whitehorn D, Holden S, Aldred M, Bogaard HJ, Church C, Coghlan G, Condliffe R, Corris PA, Danesino C, Eyries M, Gall H, Ghio S, Ghofrani HA, Gibbs JSR, Girerd B, Houweling AC, Howard L, Humbert M, Kiely DG, Kovacs G, MacKenzie Ross RV, Moledina S, Montani D, Newnham M, Olschewski A, Olschewski H, Peacock AJ, Pepke-Zaba J, Prokopenko I, Rhodes CJ, Scelsi L, Seeger W, Soubrier F, Stein DF, Suntharalingam J, Swietlik EM, Toshner MR, van Heel DA, Vonk Noordegraaf A, Waisfisz Q, Wharton J, Wort SJ, Ouwehand WH, Soranzo N, Lawrie A, Upton PD, Wilkins MR, Trembath RC, Morrell NW.

Nat Commun. 2018 Apr 12;9(1):1416. doi: 10.1038/s41467-018-03672-4.

33.

Pulmonary capillary recruitment in exercise and pulmonary hypertension.

Olschewski H, Kovacs G, Herve P.

Eur Respir J. 2018 Mar 15;51(3). pii: 1800260. doi: 10.1183/13993003.00260-2018. Print 2018 Mar. No abstract available.

PMID:
29545320
34.

Network Analysis to Risk Stratify Patients With Exercise Intolerance.

Oldham WM, Oliveira RKF, Wang RS, Opotowsky AR, Rubins DM, Hainer J, Wertheim BM, Alba GA, Choudhary G, Tornyos A, MacRae CA, Loscalzo J, Leopold JA, Waxman AB, Olschewski H, Kovacs G, Systrom DM, Maron BA.

Circ Res. 2018 Mar 16;122(6):864-876. doi: 10.1161/CIRCRESAHA.117.312482. Epub 2018 Feb 5.

35.

MicroRNAs as regulators of cisplatin-resistance in non-small cell lung carcinomas.

Fadejeva I, Olschewski H, Hrzenjak A.

Oncotarget. 2017 Dec 5;8(70):115754-115773. doi: 10.18632/oncotarget.22975. eCollection 2017 Dec 29. Review.

36.

The inflammatory cell landscape in the lungs of patients with idiopathic pulmonary arterial hypertension.

Marsh LM, Jandl K, Grünig G, Foris V, Bashir M, Ghanim B, Klepetko W, Olschewski H, Olschewski A, Kwapiszewska G.

Eur Respir J. 2018 Jan 25;51(1). pii: 1701214. doi: 10.1183/13993003.01214-2017. Print 2018 Jan.

37.

Resident cell lineages are preserved in pulmonary vascular remodeling.

Crnkovic S, Marsh LM, El Agha E, Voswinckel R, Ghanim B, Klepetko W, Stacher-Priehse E, Olschewski H, Bloch W, Bellusci S, Olschewski A, Kwapiszewska G.

J Pathol. 2018 Apr;244(4):485-498. doi: 10.1002/path.5044. Epub 2018 Mar 9.

38.

No erythropoietin-induced growth is observed in non-small cell lung cancer cells.

Frille A, Leithner K, Olschewski A, Olschewski H, Wohlkönig C, Hrzenjak A.

Int J Oncol. 2018 Feb;52(2):518-526. doi: 10.3892/ijo.2017.4225. Epub 2017 Dec 12.

PMID:
29345289
39.

Right ventricular fibrosis and dysfunction: Actual concepts and common misconceptions.

Egemnazarov B, Crnkovic S, Nagy BM, Olschewski H, Kwapiszewska G.

Matrix Biol. 2018 Aug;68-69:507-521. doi: 10.1016/j.matbio.2018.01.010. Epub 2018 Jan 16. Review.

PMID:
29343458
40.

An official European Respiratory Society statement: pulmonary haemodynamics during exercise.

Kovacs G, Herve P, Barbera JA, Chaouat A, Chemla D, Condliffe R, Garcia G, Grünig E, Howard L, Humbert M, Lau E, Laveneziana P, Lewis GD, Naeije R, Peacock A, Rosenkranz S, Saggar R, Ulrich S, Vizza D, Vonk Noordegraaf A, Olschewski H.

Eur Respir J. 2017 Nov 22;50(5). pii: 1700578. doi: 10.1183/13993003.00578-2017. Print 2017 Nov. Erratum in: Eur Respir J. 2018 Jan 18;51(1):.

41.

Mild Elevation of Pulmonary Arterial Pressure as a Predictor of Mortality.

Douschan P, Kovacs G, Avian A, Foris V, Gruber F, Olschewski A, Olschewski H.

Am J Respir Crit Care Med. 2018 Feb 15;197(4):509-516. doi: 10.1164/rccm.201706-1215OC.

PMID:
29099619
42.

Understanding exercise hemodynamics.

Olschewski H.

Pulm Circ. 2017 Jul-Sep;7(3):565-566. doi: 10.1177/2045893217728694. No abstract available.

43.

TR3 is involved in hypoxia-induced apoptosis resistance in lung cancer cells downstream of HIF-1α.

Wohlkoenig C, Leithner K, Olschewski A, Olschewski H, Hrzenjak A.

Lung Cancer. 2017 Sep;111:15-22. doi: 10.1016/j.lungcan.2017.06.013. Epub 2017 Jun 21.

PMID:
28838387
44.

Hypoxic vascular response and ventilation/perfusion matching in end-stage COPD may depend on p22phox.

Nagaraj C, Tabeling C, Nagy BM, Jain PP, Marsh LM, Papp R, Pienn M, Witzenrath M, Ghanim B, Klepetko W, Weir EK, Heschl S, Kwapiszewska G, Olschewski A, Olschewski H.

Eur Respir J. 2017 Jul 20;50(1). pii: 1601651. doi: 10.1183/13993003.01651-2016. Print 2017 Jul.

45.

Changes in pulmonary exercise haemodynamics in scleroderma: a 4-year prospective study.

Kovacs G, Avian A, Wutte N, Hafner F, Moazedi-Fürst F, Kielhauser S, Aberer E, Brodmann M, Graninger W, Foris V, Olschewski A, Olschewski H.

Eur Respir J. 2017 Jul 13;50(1). pii: 1601708. doi: 10.1183/13993003.01708-2016. Print 2017 Jul.

46.

Importance of kynurenine in pulmonary hypertension.

Nagy BM, Nagaraj C, Meinitzer A, Sharma N, Papp R, Foris V, Ghanim B, Kwapiszewska G, Kovacs G, Klepetko W, Pieber TR, Mangge H, Olschewski H, Olschewski A.

Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L741-L751. doi: 10.1152/ajplung.00517.2016. Epub 2017 Jul 13.

47.

The safety and pharmacokinetics of rapid iloprost aerosol delivery via the BREELIB nebulizer in pulmonary arterial hypertension.

Gessler T, Ghofrani HA, Held M, Klose H, Leuchte H, Olschewski H, Rosenkranz S, Fels L, Li N, Ren D, Kaiser A, Schultze-Mosgau MH, Müllinger B, Rohde B, Seeger W.

Pulm Circ. 2017 Apr-Jun;7(2):505-513. doi: 10.1177/2045893217706691. Epub 2017 May 12.

48.

Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia.

Nagy BM, Nagaraj C, Egemnazarov B, Kwapiszewska G, Stauber RE, Avian A, Olschewski H, Olschewski A.

Front Physiol. 2017 Feb 21;8:98. doi: 10.3389/fphys.2017.00098. eCollection 2017.

49.

Pulmonary Hypertension.

Hoeper MM, Ghofrani HA, Grünig E, Klose H, Olschewski H, Rosenkranz S.

Dtsch Arztebl Int. 2017 Feb 3;114(5):73-84. doi: 10.3238/arztebl.2017.0073. Review.

50.

Cardiopulmonary exercise testing for detecting pulmonary arterial hypertension in systemic sclerosis.

Dumitrescu D, Nagel C, Kovacs G, Bollmann T, Halank M, Winkler J, Hellmich M, Grünig E, Olschewski H, Ewert R, Rosenkranz S.

Heart. 2017 May;103(10):774-782. doi: 10.1136/heartjnl-2016-309981. Epub 2017 Jan 6.

PMID:
28062514

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