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Items: 1 to 50 of 253

1.

Disconnect between Fibrotic Response and Right Ventricular Dysfunction.

Crnkovic S, Egemnazarov B, Damico R, Marsh LM, Nagy BM, Douschan P, Atsina K, Kolb TM, Mathai SC, Hooper JE, Ghanim B, Klepetko W, Fruhwald F, Lassner D, Olschewski A, Olschewski H, Hassoun PM, Kwapiszewska G.

Am J Respir Crit Care Med. 2018 Dec 17. doi: 10.1164/rccm.201809-1737OC. [Epub ahead of print]

PMID:
30557518
2.

Pulmonary hypertension in chronic lung disease and hypoxia.

Nathan SD, Barbera JA, Gaine SP, Harari S, Martinez FJ, Olschewski H, Olsson KM, Peacock AJ, Pepke-Zaba J, Provencher S, Weissmann N, Seeger W.

Eur Respir J. 2018 Dec 13. pii: 1801914. doi: 10.1183/13993003.01914-2018. [Epub ahead of print]

3.

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Rhodes CJ, Batai K, Bleda M, Haimel M, Southgate L, Germain M, Pauciulo MW, Hadinnapola C, Aman J, Girerd B, Arora A, Knight J, Hanscombe KB, Karnes JH, Kaakinen M, Gall H, Ulrich A, Harbaum L, Cebola I, Ferrer J, Lutz K, Swietlik EM, Ahmad F, Amouyel P, Archer SL, Argula R, Austin ED, Badesch D, Bakshi S, Barnett C, Benza R, Bhatt N, Bogaard HJ, Burger CD, Chakinala M, Church C, Coghlan JG, Condliffe R, Corris PA, Danesino C, Debette S, Elliott CG, Elwing J, Eyries M, Fortin T, Franke A, Frantz RP, Frost A, Garcia JGN, Ghio S, Ghofrani HA, Gibbs JSR, Harley J, He H, Hill NS, Hirsch R, Houweling AC, Howard LS, Ivy D, Kiely DG, Klinger J, Kovacs G, Lahm T, Laudes M, Machado RD, Ross RVM, Marsolo K, Martin LJ, Moledina S, Montani D, Nathan SD, Newnham M, Olschewski A, Olschewski H, Oudiz RJ, Ouwehand WH, Peacock AJ, Pepke-Zaba J, Rehman Z, Robbins I, Roden DM, Rosenzweig EB, Saydain G, Scelsi L, Schilz R, Seeger W, Shaffer CM, Simms RW, Simon M, Sitbon O, Suntharalingam J, Tang H, Tchourbanov AY, Thenappan T, Torres F, Toshner MR, Treacy CM, Noordegraaf AV, Waisfisz Q, Walsworth AK, Walter RE, Wharton J, White RJ, Wilt J, Wort SJ, Yung D, Lawrie A, Humbert M, Soubrier F, Trégouët DA, Prokopenko I, Kittles R, Gräf S, Nichols WC, Trembath RC, Desai AA, Morrell NW, Wilkins MR; UK NIHR BioResource Rare Diseases Consortium; UK PAH Cohort Study Consortium; US PAH Biobank Consortium.

Lancet Respir Med. 2018 Dec 5. pii: S2213-2600(18)30409-0. doi: 10.1016/S2213-2600(18)30409-0. [Epub ahead of print]

PMID:
30527956
4.

Long non-coding RNAs influence the transcriptome in pulmonary arterial hypertension: the role of PAXIP1-AS1.

Jandl K, Thekkekara Puthenparampil H, Marsh LM, Hoffmann J, Wilhelm J, Veith C, Sinn K, Klepetko W, Olschewski H, Olschewski A, Brock M, Kwapiszewska G.

J Pathol. 2018 Nov 18. doi: 10.1002/path.5195. [Epub ahead of print]

PMID:
30450722
5.

Crackle and Breathing Phase Detection in Lung Sounds with Deep Bidirectional Gated Recurrent Neural Networks.

Messner E, Fediuk M, Swatek P, Scheidl S, Smolle-Juttner FM, Olschewski H, Pernkopf F.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:356-359. doi: 10.1109/EMBC.2018.8512237.

PMID:
30440410
6.

Imatinib for right heart failure in COPD.

Douschan P, Kovacs G, Foris V, Kuehnelt-Leddihn M, Olschewski H.

Pulm Circ. 2019 Jan-Mar;9(1):2045894018816974. doi: 10.1177/2045894018816974. Epub 2018 Nov 15.

PMID:
30430893
7.

Cologne consensus conference on pulmonary hypertension - Update 2018.

Rosenkranz S, Ghofrani HA, Grünig E, Klose H, Olschewski H, Hoeper MM.

Int J Cardiol. 2018 Sep 22. pii: S0167-5273(18)35665-1. doi: 10.1016/j.ijcard.2018.09.064. [Epub ahead of print] No abstract available.

PMID:
30344062
8.

Clinical-Pathological Conference Series from the Medical University of Graz : Case No 168: A 28-year-old Syrian refugee with severe abdominal pain and eosinophilia.

Fabian E, Auer H, Kump P, Krause R, Wagner M, Fuchsjäger M, Janek E, Olschewski H, Krejs GJ.

Wien Klin Wochenschr. 2018 Oct;130(19-20):581-588. doi: 10.1007/s00508-018-1395-z. Epub 2018 Oct 15. No abstract available.

9.

Are anticoagulants still indicated in pulmonary arterial hypertension?

Olschewski H, Rich S.

Pulm Circ. 2018 Oct-Dec;8(4):2045894018807681. doi: 10.1177/2045894018807681. Epub 2018 Oct 4.

10.

Advancing into the details of pulmonary haemodynamics during exercise.

Kovacs G, Olschewski H.

Eur Respir J. 2018 Sep 17;52(3). pii: 1801578. doi: 10.1183/13993003.01578-2018. Print 2018 Sep. No abstract available.

PMID:
30224546
11.

Transcriptome profiling reveals the complexity of pirfenidone effects in idiopathic pulmonary fibrosis.

Kwapiszewska G, Gungl A, Wilhelm J, Marsh LM, Thekkekara Puthenparampil H, Sinn K, Didiasova M, Klepetko W, Kosanovic D, Schermuly RT, Wujak L, Weiss B, Schaefer L, Schneider M, Kreuter M, Olschewski A, Seeger W, Olschewski H, Wygrecka M.

Eur Respir J. 2018 Nov 22;52(5). pii: 1800564. doi: 10.1183/13993003.00564-2018. Print 2018 Nov.

PMID:
30166321
12.

Pulmonary hypertension due to lung diseases: Updated recommendations from the Cologne Consensus Conference 2018.

Olschewski H, Behr J, Bremer H, Claussen M, Douschan P, Halank M, Held M, Hoeper MM, Holt S, Klose H, Krüger S, Lange TJ, Reichenberger F, Skowasch D, Ulrich S, Wilkens H, Seeger W.

Int J Cardiol. 2018 Aug 11. pii: S0167-5273(18)34353-5. doi: 10.1016/j.ijcard.2018.08.043. [Epub ahead of print]

PMID:
30131231
13.

Whole-Body Lung Function Test-Derived Outcome Predictors in Allogenic Stem Cell Transplantation.

Scheidl S, Zinke-Cerwenka W, Flick H, Gaal S, Avian A, Greinix H, Olschewski H.

Biol Blood Marrow Transplant. 2018 Jul 29. pii: S1083-8791(18)30425-7. doi: 10.1016/j.bbmt.2018.07.036. [Epub ahead of print]

PMID:
30064013
14.

Should patients with pulmonary hypertension fly and climb?

Kovacs G, Olschewski H.

Int J Cardiol. 2018 Nov 1;270:276-277. doi: 10.1016/j.ijcard.2018.07.054. Epub 2018 Jul 12. No abstract available.

PMID:
30031623
15.

Biomarkers for Pulmonary Vascular Remodeling in Systemic Sclerosis: A Pathophysiological Approach.

Odler B, Foris V, Gungl A, Müller V, Hassoun PM, Kwapiszewska G, Olschewski H, Kovacs G.

Front Physiol. 2018 Jun 19;9:587. doi: 10.3389/fphys.2018.00587. eCollection 2018. Review.

16.

Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.

Fazakas C, Nagaraj C, Zabini D, Végh AG, Marsh LM, Wilhelm I, Krizbai IA, Olschewski H, Olschewski A, Bálint Z.

Front Physiol. 2018 May 15;9:537. doi: 10.3389/fphys.2018.00537. eCollection 2018.

17.

The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells.

Leithner K, Triebl A, Trötzmüller M, Hinteregger B, Leko P, Wieser BI, Grasmann G, Bertsch AL, Züllig T, Stacher E, Valli A, Prassl R, Olschewski A, Harris AL, Köfeler HC, Olschewski H, Hrzenjak A.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6225-6230. doi: 10.1073/pnas.1719871115. Epub 2018 May 29.

18.

Healthy Lung Vessel Morphology Derived From Thoracic Computed Tomography.

Pienn M, Burgard C, Payer C, Avian A, Urschler M, Stollberger R, Olschewski A, Olschewski H, Johnson T, Meinel FG, Bálint Z.

Front Physiol. 2018 Apr 10;9:346. doi: 10.3389/fphys.2018.00346. eCollection 2018.

19.

Pulmonary Vascular Involvement in Chronic Obstructive Pulmonary Disease. Is There a Pulmonary Vascular Phenotype?

Kovacs G, Agusti A, Barberà JA, Celli B, Criner G, Humbert M, Sin DD, Voelkel N, Olschewski H.

Am J Respir Crit Care Med. 2018 Oct 15;198(8):1000-1011. doi: 10.1164/rccm.201801-0095PP. No abstract available.

PMID:
29746142
20.

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension.

Gräf S, Haimel M, Bleda M, Hadinnapola C, Southgate L, Li W, Hodgson J, Liu B, Salmon RM, Southwood M, Machado RD, Martin JM, Treacy CM, Yates K, Daugherty LC, Shamardina O, Whitehorn D, Holden S, Aldred M, Bogaard HJ, Church C, Coghlan G, Condliffe R, Corris PA, Danesino C, Eyries M, Gall H, Ghio S, Ghofrani HA, Gibbs JSR, Girerd B, Houweling AC, Howard L, Humbert M, Kiely DG, Kovacs G, MacKenzie Ross RV, Moledina S, Montani D, Newnham M, Olschewski A, Olschewski H, Peacock AJ, Pepke-Zaba J, Prokopenko I, Rhodes CJ, Scelsi L, Seeger W, Soubrier F, Stein DF, Suntharalingam J, Swietlik EM, Toshner MR, van Heel DA, Vonk Noordegraaf A, Waisfisz Q, Wharton J, Wort SJ, Ouwehand WH, Soranzo N, Lawrie A, Upton PD, Wilkins MR, Trembath RC, Morrell NW.

Nat Commun. 2018 Apr 12;9(1):1416. doi: 10.1038/s41467-018-03672-4.

21.

Pulmonary capillary recruitment in exercise and pulmonary hypertension.

Olschewski H, Kovacs G, Herve P.

Eur Respir J. 2018 Mar 15;51(3). pii: 1800260. doi: 10.1183/13993003.00260-2018. Print 2018 Mar. No abstract available.

PMID:
29545320
22.

Network Analysis to Risk Stratify Patients With Exercise Intolerance.

Oldham WM, Oliveira RKF, Wang RS, Opotowsky AR, Rubins DM, Hainer J, Wertheim BM, Alba GA, Choudhary G, Tornyos A, MacRae CA, Loscalzo J, Leopold JA, Waxman AB, Olschewski H, Kovacs G, Systrom DM, Maron BA.

Circ Res. 2018 Mar 16;122(6):864-876. doi: 10.1161/CIRCRESAHA.117.312482. Epub 2018 Feb 5.

PMID:
29437835
23.

MicroRNAs as regulators of cisplatin-resistance in non-small cell lung carcinomas.

Fadejeva I, Olschewski H, Hrzenjak A.

Oncotarget. 2017 Dec 5;8(70):115754-115773. doi: 10.18632/oncotarget.22975. eCollection 2017 Dec 29. Review.

24.

The inflammatory cell landscape in the lungs of patients with idiopathic pulmonary arterial hypertension.

Marsh LM, Jandl K, Grünig G, Foris V, Bashir M, Ghanim B, Klepetko W, Olschewski H, Olschewski A, Kwapiszewska G.

Eur Respir J. 2018 Jan 25;51(1). pii: 1701214. doi: 10.1183/13993003.01214-2017. Print 2018 Jan.

25.

Resident cell lineages are preserved in pulmonary vascular remodeling.

Crnkovic S, Marsh LM, El Agha E, Voswinckel R, Ghanim B, Klepetko W, Stacher-Priehse E, Olschewski H, Bloch W, Bellusci S, Olschewski A, Kwapiszewska G.

J Pathol. 2018 Apr;244(4):485-498. doi: 10.1002/path.5044. Epub 2018 Mar 9.

26.

No erythropoietin-induced growth is observed in non-small cell lung cancer cells.

Frille A, Leithner K, Olschewski A, Olschewski H, Wohlkönig C, Hrzenjak A.

Int J Oncol. 2018 Feb;52(2):518-526. doi: 10.3892/ijo.2017.4225. Epub 2017 Dec 12.

PMID:
29345289
27.

Right ventricular fibrosis and dysfunction: Actual concepts and common misconceptions.

Egemnazarov B, Crnkovic S, Nagy BM, Olschewski H, Kwapiszewska G.

Matrix Biol. 2018 Aug;68-69:507-521. doi: 10.1016/j.matbio.2018.01.010. Epub 2018 Jan 16. Review.

PMID:
29343458
28.

An official European Respiratory Society statement: pulmonary haemodynamics during exercise.

Kovacs G, Herve P, Barbera JA, Chaouat A, Chemla D, Condliffe R, Garcia G, Grünig E, Howard L, Humbert M, Lau E, Laveneziana P, Lewis GD, Naeije R, Peacock A, Rosenkranz S, Saggar R, Ulrich S, Vizza D, Vonk Noordegraaf A, Olschewski H.

Eur Respir J. 2017 Nov 22;50(5). pii: 1700578. doi: 10.1183/13993003.00578-2017. Print 2017 Nov. Erratum in: Eur Respir J. 2018 Jan 18;51(1):.

PMID:
29167297
29.

Mild Elevation of Pulmonary Arterial Pressure as a Predictor of Mortality.

Douschan P, Kovacs G, Avian A, Foris V, Gruber F, Olschewski A, Olschewski H.

Am J Respir Crit Care Med. 2018 Feb 15;197(4):509-516. doi: 10.1164/rccm.201706-1215OC.

PMID:
29099619
30.

Understanding exercise hemodynamics.

Olschewski H.

Pulm Circ. 2017 Jul-Sep;7(3):565-566. doi: 10.1177/2045893217728694. No abstract available.

31.

TR3 is involved in hypoxia-induced apoptosis resistance in lung cancer cells downstream of HIF-1α.

Wohlkoenig C, Leithner K, Olschewski A, Olschewski H, Hrzenjak A.

Lung Cancer. 2017 Sep;111:15-22. doi: 10.1016/j.lungcan.2017.06.013. Epub 2017 Jun 21.

PMID:
28838387
32.

Hypoxic vascular response and ventilation/perfusion matching in end-stage COPD may depend on p22phox.

Nagaraj C, Tabeling C, Nagy BM, Jain PP, Marsh LM, Papp R, Pienn M, Witzenrath M, Ghanim B, Klepetko W, Weir EK, Heschl S, Kwapiszewska G, Olschewski A, Olschewski H.

Eur Respir J. 2017 Jul 20;50(1). pii: 1601651. doi: 10.1183/13993003.01651-2016. Print 2017 Jul.

PMID:
28729471
33.

Changes in pulmonary exercise haemodynamics in scleroderma: a 4-year prospective study.

Kovacs G, Avian A, Wutte N, Hafner F, Moazedi-Fürst F, Kielhauser S, Aberer E, Brodmann M, Graninger W, Foris V, Olschewski A, Olschewski H.

Eur Respir J. 2017 Jul 13;50(1). pii: 1601708. doi: 10.1183/13993003.01708-2016. Print 2017 Jul.

PMID:
28705939
34.

Importance of kynurenine in pulmonary hypertension.

Nagy BM, Nagaraj C, Meinitzer A, Sharma N, Papp R, Foris V, Ghanim B, Kwapiszewska G, Kovacs G, Klepetko W, Pieber TR, Mangge H, Olschewski H, Olschewski A.

Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L741-L751. doi: 10.1152/ajplung.00517.2016. Epub 2017 Jul 13.

35.

The safety and pharmacokinetics of rapid iloprost aerosol delivery via the BREELIB nebulizer in pulmonary arterial hypertension.

Gessler T, Ghofrani HA, Held M, Klose H, Leuchte H, Olschewski H, Rosenkranz S, Fels L, Li N, Ren D, Kaiser A, Schultze-Mosgau MH, Müllinger B, Rohde B, Seeger W.

Pulm Circ. 2017 Apr-Jun;7(2):505-513. doi: 10.1177/2045893217706691. Epub 2017 May 12.

36.

Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia.

Nagy BM, Nagaraj C, Egemnazarov B, Kwapiszewska G, Stauber RE, Avian A, Olschewski H, Olschewski A.

Front Physiol. 2017 Feb 21;8:98. doi: 10.3389/fphys.2017.00098. eCollection 2017.

37.

Pulmonary Hypertension.

Hoeper MM, Ghofrani HA, Grünig E, Klose H, Olschewski H, Rosenkranz S.

Dtsch Arztebl Int. 2017 Feb 3;114(5):73-84. doi: 10.3238/arztebl.2017.0073. Review.

38.

Cardiopulmonary exercise testing for detecting pulmonary arterial hypertension in systemic sclerosis.

Dumitrescu D, Nagel C, Kovacs G, Bollmann T, Halank M, Winkler J, Hellmich M, Grünig E, Olschewski H, Ewert R, Rosenkranz S.

Heart. 2017 May;103(10):774-782. doi: 10.1136/heartjnl-2016-309981. Epub 2017 Jan 6.

PMID:
28062514
39.

Use of ECG and Other Simple Non-Invasive Tools to Assess Pulmonary Hypertension.

Kovacs G, Avian A, Foris V, Tscherner M, Kqiku X, Douschan P, Bachmaier G, Olschewski A, Matucci-Cerinic M, Olschewski H.

PLoS One. 2016 Dec 28;11(12):e0168706. doi: 10.1371/journal.pone.0168706. eCollection 2016.

40.

[ESC guidelines 2015 pulmonary hypertension: diagnosis and treatment].

Opitz C, Rosenkranz S, Ghofrani HA, Grünig E, Klose H, Olschewski H, Hoeper M.

Dtsch Med Wochenschr. 2016 Nov;141(24):1764-1769. Epub 2016 Nov 30. German.

PMID:
27903027
41.

[Pulmonary Hypertension: Cologne Consensus Conference 2016].

Rosenkranz S, Ghofrani HA, Grünig E, Klose H, Olschewski H, Opitz C, Hoeper M.

Dtsch Med Wochenschr. 2016 Nov;141(24):1778-1782. Epub 2016 Nov 8. Review. German.

PMID:
27825176
42.

[Pulmonary hypertension due to chronic lung disease: Recommendations of the Cologne Consensus Conference 2016].

Olschewski H, Behr J, Bremer H, Claussen M, Douschan P, Halank M, Held M, Hoeper MM, Holt S, Klose H, Krüger S, Lange TJ, Reichenberger F, Skowasch D, Ulrich S, Wilkens H, Seeger W.

Dtsch Med Wochenschr. 2016 Oct;141(S 01):S57-S61. Epub 2016 Oct 19. German.

PMID:
27760451
43.

Why we should care about the mysteries of pulmonary hypertension.

Olschewski H.

Pulm Circ. 2016 Sep;6(3):249-50. doi: 10.1086/687367. No abstract available.

44.

Docosahexaenoic acid causes rapid pulmonary arterial relaxation via KCa channel-mediated hyperpolarisation in pulmonary hypertension.

Nagaraj C, Tang B, Nagy BM, Papp R, Jain PP, Marsh LM, Meredith AL, Ghanim B, Klepetko W, Kwapiszewska G, Weir EK, Olschewski H, Olschewski A.

Eur Respir J. 2016 Oct;48(4):1127-1136. doi: 10.1183/13993003.01814-2015. Epub 2016 Aug 18.

45.

Counter-clockwise vortical blood flow in the main pulmonary artery in a patient with patent ductus arteriosus with pulmonary arterial hypertension: a cardiac magnetic resonance imaging case report.

Reiter G, Reiter U, Kovacs G, Adelsmayr G, Greiser A, Stalder AF, Olschewski H, Fuchsjäger M.

BMC Med Imaging. 2016 Aug 8;16(1):45. doi: 10.1186/s12880-016-0150-z.

46.

TASK-1 Regulates Apoptosis and Proliferation in a Subset of Non-Small Cell Lung Cancers.

Leithner K, Hirschmugl B, Li Y, Tang B, Papp R, Nagaraj C, Stacher E, Stiegler P, Lindenmann J, Olschewski A, Olschewski H, Hrzenjak A.

PLoS One. 2016 Jun 13;11(6):e0157453. doi: 10.1371/journal.pone.0157453. eCollection 2016.

47.

Does exercise pulmonary hypertension exist?

Lau EM, Chemla D, Whyte K, Kovacs G, Olschewski H, Herve P.

Curr Opin Pulm Med. 2016 Sep;22(5):400-7. doi: 10.1097/MCP.0000000000000292. Review.

PMID:
27270182
48.

Automated integer programming based separation of arteries and veins from thoracic CT images.

Payer C, Pienn M, Bálint Z, Shekhovtsov A, Talakic E, Nagy E, Olschewski A, Olschewski H, Urschler M.

Med Image Anal. 2016 Dec;34:109-122. doi: 10.1016/j.media.2016.05.002. Epub 2016 May 6.

PMID:
27189777
49.

[Research in Austria - the Ludwig Boltzmann Institute for Lung Vascular Research].

Kovacs G, Kleinschek D, Kwapiszewska G, Bálint Z, Olschewski H, Olschewski A.

Pneumologie. 2016 May;70(5):331-5. doi: 10.1055/s-0042-104767. Epub 2016 May 11. Review. German.

PMID:
27168041
50.

Safety and tolerability of acetylcysteine and pirfenidone combination therapy in idiopathic pulmonary fibrosis: a randomised, double-blind, placebo-controlled, phase 2 trial.

Behr J, Bendstrup E, Crestani B, Günther A, Olschewski H, Sköld CM, Wells A, Wuyts W, Koschel D, Kreuter M, Wallaert B, Lin CY, Beck J, Albera C.

Lancet Respir Med. 2016 Jun;4(6):445-53. doi: 10.1016/S2213-2600(16)30044-3. Epub 2016 May 5.

PMID:
27161257

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