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Apolipoprotein E Interferes with IAPP Aggregation and Protects Pericytes from IAPP-Induced Toxicity.

Gharibyan AL, Islam T, Pettersson N, Golchin SA, Lundgren J, Johansson G, Genot M, Schultz N, Wennström M, Olofsson A.

Biomolecules. 2020 Jan 14;10(1). pii: E134. doi: 10.3390/biom10010134.


Apolipoprotein E impairs amyloid-β fibril elongation and maturation.

Islam T, Gharibyan AL, Golchin SA, Pettersson N, Brännström K, Hedberg I, Virta MM, Olofsson L, Olofsson A.

FEBS J. 2020 Mar;287(6):1208-1219. doi: 10.1111/febs.15075. Epub 2019 Oct 9.


Patterns of participation: Facilitating and hindering aspects related to places for activities outside the home after stroke.

Malinowsky C, Olofsson A, Nyman A, Lund ML.

Scand J Occup Ther. 2019 Sep 28:1-9. doi: 10.1080/11038128.2019.1668958. [Epub ahead of print]


Patient safety culture among European cancer nurses-An exploratory, cross-sectional survey comparing data from Estonia, Germany, Netherlands, and United Kingdom.

Sharp L, Rannus K, Olofsson A, Kelly D, Oldenmenger WH; EONS RECaN group.

J Adv Nurs. 2019 Dec;75(12):3535-3543. doi: 10.1111/jan.14177. Epub 2019 Sep 4.


Patient-reported perceptions of care after the introduction of a new advanced cancer nursing role in Sweden.

Westman B, Ullgren H, Olofsson A, Sharp L.

Eur J Oncol Nurs. 2019 Aug;41:41-48. doi: 10.1016/j.ejon.2019.05.009. Epub 2019 Jun 1.


De novo dNTP production is essential for normal postnatal murine heart development.

Tran P, Wanrooij PH, Lorenzon P, Sharma S, Thelander L, Nilsson AK, Olofsson AK, Medini P, von Hofsten J, Stål P, Chabes A.

J Biol Chem. 2019 Nov 1;294(44):15889-15897. doi: 10.1074/jbc.RA119.009492. Epub 2019 Jul 12.


Assembly mechanisms of the bacterial cytoskeletal protein FilP.

Javadi A, Söderholm N, Olofsson A, Flärdh K, Sandblad L.

Life Sci Alliance. 2019 Jun 26;2(3). pii: e201800290. doi: 10.26508/lsa.201800290. Print 2019 Jun.


The pre- and postoperative illness trajectory in patients with pituitary tumours.

Jakobsson Ung E, Olofsson AC, Björkman I, Hallén T, Olsson DS, Ragnarsson O, Skoglund T, Jakobsson S, Johannsson G.

Endocr Connect. 2019 Jul;8(7):878-886. doi: 10.1530/EC-19-0202.


Pyridine-Fused 2-Pyridones via Povarov and A3 Reactions: Rapid Generation of Highly Functionalized Tricyclic Heterocycles Capable of Amyloid Fibril Binding.

Singh P, Adolfsson DE, Ådén J, Cairns AG, Bartens C, Brännström K, Olofsson A, Almqvist F.

J Org Chem. 2019 Apr 5;84(7):3887-3903. doi: 10.1021/acs.joc.8b03015. Epub 2019 Mar 20.


Everyday activities outside the home are a struggle: Narratives from two persons with acquired brain injury.

Olofsson A, Larsson Lund M, Nyman A.

Scand J Occup Ther. 2018 Oct 10:1-10. doi: 10.1080/11038128.2018.1495762. [Epub ahead of print]


Scanning electron microscopy as a tool for evaluating morphology of amyloid structures formed on surface plasmon resonance chips.

Bra Nnstro M K, Gharibyan AL, Islam T, Iakovleva I, Nilsson L, Lee CC, Sandblad L, Pamren A, Olofsson A.

Data Brief. 2018 May 26;19:1166-1170. doi: 10.1016/j.dib.2018.05.129. eCollection 2018 Aug.


Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.

Zhang J, Grundström C, Brännström K, Iakovleva I, Lindberg M, Olofsson A, Andersson PL, Sauer-Eriksson AE.

Environ Sci Technol. 2018 Oct 16;52(20):11865-11874. doi: 10.1021/acs.est.8b03581. Epub 2018 Oct 2.


Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells.

Rajan A, Persson BD, Frängsmyr L, Olofsson A, Sandblad L, Heino J, Takada Y, Mould AP, Schnapp LM, Gall J, Arnberg N.

Sci Rep. 2018 Jul 3;8(1):10019. doi: 10.1038/s41598-018-28255-7.


Access to supportive care during and after cancer treatment and the impact of socioeconomic factors.

Sharp L, Westman B, Olofsson A, Leppänen A, Henriksson R.

Acta Oncol. 2018 Oct;57(10):1303-1310. doi: 10.1080/0284186X.2018.1484157. Epub 2018 Jun 27.


Transthyretin Interferes with Aβ Amyloid Formation by Redirecting Oligomeric Nuclei into Non-Amyloid Aggregates.

Nilsson L, Pamrén A, Islam T, Brännström K, Golchin SA, Pettersson N, Iakovleva I, Sandblad L, Gharibyan AL, Olofsson A.

J Mol Biol. 2018 Aug 17;430(17):2722-2733. doi: 10.1016/j.jmb.2018.06.005. Epub 2018 Jun 8.


The Properties of Amyloid-β Fibrils Are Determined by their Path of Formation.

Brännström K, Islam T, Gharibyan AL, Iakovleva I, Nilsson L, Lee CC, Sandblad L, Pamrén A, Olofsson A.

J Mol Biol. 2018 Jun 22;430(13):1940-1949. doi: 10.1016/j.jmb.2018.05.001. Epub 2018 May 9.


Amyloid-beta 1-40 is associated with alterations in NG2+ pericyte population ex vivo and in vitro.

Schultz N, Brännström K, Byman E, Moussaud S, Nielsen HM; Netherlands Brain Bank, Olofsson A, Wennström M.

Aging Cell. 2018 Jun;17(3):e12728. doi: 10.1111/acel.12728. Epub 2018 Feb 17.


PreHospital Ambulance Stroke Test - pilot study of a novel stroke test.

Andsberg G, Esbjörnsson M, Olofsson A, Lindgren A, Norrving B, von Euler M.

Scand J Trauma Resusc Emerg Med. 2017 Apr 11;25(1):37. doi: 10.1186/s13049-017-0377-x.


Helicobacter pylori Adapts to Chronic Infection and Gastric Disease via pH-Responsive BabA-Mediated Adherence.

Bugaytsova JA, Björnham O, Chernov YA, Gideonsson P, Henriksson S, Mendez M, Sjöström R, Mahdavi J, Shevtsova A, Ilver D, Moonens K, Quintana-Hayashi MP, Moskalenko R, Aisenbrey C, Bylund G, Schmidt A, Åberg A, Brännström K, Königer V, Vikström S, Rakhimova L, Hofer A, Ögren J, Liu H, Goldman MD, Whitmire JM, Ådén J, Younson J, Kelly CG, Gilman RH, Chowdhury A, Mukhopadhyay AK, Nair GB, Papadakos KS, Martinez-Gonzalez B, Sgouras DN, Engstrand L, Unemo M, Danielsson D, Suerbaum S, Oscarson S, Morozova-Roche LA, Olofsson A, Gröbner G, Holgersson J, Esberg A, Strömberg N, Landström M, Eldridge AM, Chromy BA, Hansen LM, Solnick JV, Lindén SK, Haas R, Dubois A, Merrell DS, Schedin S, Remaut H, Arnqvist A, Berg DE, Borén T.

Cell Host Microbe. 2017 Mar 8;21(3):376-389. doi: 10.1016/j.chom.2017.02.013.


The role of histidines in amyloid β fibril assembly.

Brännström K, Islam T, Sandblad L, Olofsson A.

FEBS Lett. 2017 Apr;591(8):1167-1175. doi: 10.1002/1873-3468.12616. Epub 2017 Apr 3.


Structure-Based Virtual Screening Protocol for in Silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin.

Zhang J, Begum A, Brännström K, Grundström C, Iakovleva I, Olofsson A, Sauer-Eriksson AE, Andersson PL.

Environ Sci Technol. 2016 Nov 1;50(21):11984-11993. Epub 2016 Oct 10.


Parenthood and Worrying About Climate Change: The Limitations of Previous Approaches.

Ekholm S, Olofsson A.

Risk Anal. 2017 Feb;37(2):305-314. doi: 10.1111/risa.12626. Epub 2016 May 10.


Tetrabromobisphenol A Is an Efficient Stabilizer of the Transthyretin Tetramer.

Iakovleva I, Begum A, Brännström K, Wijsekera A, Nilsson L, Zhang J, Andersson PL, Sauer-Eriksson AE, Olofsson A.

PLoS One. 2016 Apr 19;11(4):e0153529. doi: 10.1371/journal.pone.0153529. eCollection 2016.


Modifications of the 7-Hydroxyl Group of the Transthyretin Ligand Luteolin Provide Mechanistic Insights into Its Binding Properties and High Plasma Specificity.

Nilsson L, Larsson A, Begum A, Iakovleva I, Carlsson M, Brännström K, Sauer-Eriksson AE, Olofsson A.

PLoS One. 2016 Apr 6;11(4):e0153112. doi: 10.1371/journal.pone.0153112. eCollection 2016.


Changes in cochlear function related to acoustic stimulation of cervical vestibular evoked myogenic potential stimulation.

Strömberg AK, Olofsson Å, Westin M, Duan M, Stenfelt S.

Hear Res. 2016 Oct;340:43-49. doi: 10.1016/j.heares.2015.12.022. Epub 2015 Dec 25.


Corneal-Reflection Eye-Tracking Technique for the Assessment of Horizontal Sound Localization Accuracy from 6 Months of Age.

Asp F, Olofsson Å, Berninger E.

Ear Hear. 2016 Mar-Apr;37(2):e104-18. doi: 10.1097/AUD.0000000000000235.


Academic Achievement of University Students with Dyslexia.

Olofsson Å, Taube K, Ahl A.

Dyslexia. 2015 Nov;21(4):338-49. doi: 10.1002/dys.1517. Epub 2015 Oct 13.


Everyday places, heterosexist spaces and risk in contemporary Sweden.

Nygren KG, Öhman S, Olofsson A.

Cult Health Sex. 2016;18(1):45-57. doi: 10.1080/13691058.2015.1063814. Epub 2015 Aug 5.


Enthalpic Forces Correlate with the Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma.

Iakovleva I, Brännström K, Nilsson L, Gharibyan AL, Begum A, Anan I, Walfridsson M, Sauer-Eriksson AE, Olofsson A.

J Med Chem. 2015 Aug 27;58(16):6507-15. doi: 10.1021/acs.jmedchem.5b00544. Epub 2015 Aug 11.


The flavonoid luteolin, but not luteolin-7-O-glucoside, prevents a transthyretin mediated toxic response.

Iakovleva I, Begum A, Pokrzywa M, Walfridsson M, Sauer-Eriksson AE, Olofsson A.

PLoS One. 2015 May 28;10(5):e0128222. doi: 10.1371/journal.pone.0128222. eCollection 2015.


Helicobacter pylori vesicles carrying CagA localize in the vicinity of cell-cell contacts and induce histone H1 binding to ATP in epithelial cells.

Turkina MV, Olofsson A, Magnusson KE, Arnqvist A, Vikström E.

FEMS Microbiol Lett. 2015 Jun;362(11). pii: fnv076. doi: 10.1093/femsle/fnv076. Epub 2015 May 7.


The N-terminal region of amyloid β controls the aggregation rate and fibril stability at low pH through a gain of function mechanism.

Brännström K, Öhman A, Nilsson L, Pihl M, Sandblad L, Olofsson A.

J Am Chem Soc. 2014 Aug 6;136(31):10956-64. doi: 10.1021/ja503535m. Epub 2014 Jul 28.


A repetitive DNA element regulates expression of the Helicobacter pylori sialic acid binding adhesin by a rheostat-like mechanism.

Åberg A, Gideonsson P, Vallström A, Olofsson A, Öhman C, Rakhimova L, Borén T, Engstrand L, Brännström K, Arnqvist A.

PLoS Pathog. 2014 Jul 3;10(7):e1004234. doi: 10.1371/journal.ppat.1004234. eCollection 2014 Jul.


Interaction studies of the human and Arabidopsis thaliana Med25-ACID proteins with the herpes simplex virus VP16- and plant-specific Dreb2a transcription factors.

Aguilar X, Blomberg J, Brännström K, Olofsson A, Schleucher J, Björklund S.

PLoS One. 2014 May 29;9(5):e98575. doi: 10.1371/journal.pone.0098575. eCollection 2014.


Can physicians be replaced with gynecological teaching women to train medical students in their first pelvic examination? A pilot study from Northern Sweden.

Grankvist O, Olofsson AD, Isaksson RM.

Patient Educ Couns. 2014 Jul;96(1):50-4. doi: 10.1016/j.pec.2014.04.013. Epub 2014 May 5.


Uptake of Helicobacter pylori vesicles is facilitated by clathrin-dependent and clathrin-independent endocytic pathways.

Olofsson A, Nygård Skalman L, Obi I, Lundmark R, Arnqvist A.

mBio. 2014 May 20;5(3):e00979-14. doi: 10.1128/mBio.00979-14.


Tinnitus and other auditory problems - occupational noise exposure below risk limits may cause inner ear dysfunction.

Lindblad AC, Rosenhall U, Olofsson Å, Hagerman B.

PLoS One. 2014 May 14;9(5):e97377. doi: 10.1371/journal.pone.0097377. eCollection 2014.


A generic method for design of oligomer-specific antibodies.

Brännström K, Lindhagen-Persson M, Gharibyan AL, Iakovleva I, Vestling M, Sellin ME, Brännström T, Morozova-Roche L, Forsgren L, Olofsson A.

PLoS One. 2014 Mar 11;9(3):e90857. doi: 10.1371/journal.pone.0090857. eCollection 2014.


Analysis of click-evoked auditory brainstem responses using time domain cross-correlations between interleaved responses.

Berninger E, Olofsson A, Leijon A.

Ear Hear. 2014 May-Jun;35(3):318-29. doi: 10.1097/01.aud.0000441035.40169.f2.


The role of pro-inflammatory S100A9 in Alzheimer's disease amyloid-neuroinflammatory cascade.

Wang C, Klechikov AG, Gharibyan AL, Wärmländer SK, Jarvet J, Zhao L, Jia X, Narayana VK, Shankar SK, Olofsson A, Brännström T, Mu Y, Gräslund A, Morozova-Roche LA.

Acta Neuropathol. 2014 Apr;127(4):507-22. doi: 10.1007/s00401-013-1208-4. Epub 2013 Nov 16. Erratum in: Acta Neuropathol. 2014 Sep;128(3):461.


Transthyretin is dysregulated in preeclampsia, and its native form prevents the onset of disease in a preclinical mouse model.

Kalkunte SS, Neubeck S, Norris WE, Cheng SB, Kostadinov S, Vu Hoang D, Ahmed A, von Eggeling F, Shaikh Z, Padbury J, Berg G, Olofsson A, Markert UR, Sharma S.

Am J Pathol. 2013 Nov;183(5):1425-1436. doi: 10.1016/j.ajpath.2013.07.022. Epub 2013 Sep 10.


Modulation of α-synuclein fibrillization by ring-fused 2-pyridones: templation and inhibition involve oligomers with different structure.

Horvath I, Sellstedt M, Weise C, Nordvall LM, Krishna Prasad G, Olofsson A, Larsson G, Almqvist F, Wittung-Stafshede P.

Arch Biochem Biophys. 2013 Apr 15;532(2):84-90. doi: 10.1016/ Epub 2013 Feb 9.


Structural topology and activation of an initial adenylate kinase-substrate complex.

Ådén J, Weise CF, Brännström K, Olofsson A, Wolf-Watz M.

Biochemistry. 2013 Feb 12;52(6):1055-61. doi: 10.1021/bi301460k. Epub 2013 Feb 1.


Ca(2+) enhances Aβ polymerization rate and fibrillar stability in a dynamic manner.

Brännström K, Ohman A, Lindhagen-Persson M, Olofsson A.

Biochem J. 2013 Feb 15;450(1):189-97. doi: 10.1042/BJ20121583.


The C-terminal repeating units of CsgB direct bacterial functional amyloid nucleation.

Hammer ND, McGuffie BA, Zhou Y, Badtke MP, Reinke AA, Brännström K, Gestwicki JE, Olofsson A, Almqvist F, Chapman MR.

J Mol Biol. 2012 Sep 21;422(3):376-89. doi: 10.1016/j.jmb.2012.05.043. Epub 2012 Jun 7.


Characterization of SPINK9, a KLK5-specific inhibitor expressed in palmo-plantar epidermis.

Brännström K, Ohman A, von Pawel Rammingen U, Olofsson A, Brattsand M.

Biol Chem. 2012 Apr;393(5):369-77. doi: 10.1515/hsz-2011-0238.


Interactions between DNA, transcriptional regulator Dreb2a and the Med25 mediator subunit from Arabidopsis thaliana involve conformational changes.

Blomberg J, Aguilar X, Brännström K, Rautio L, Olofsson A, Wittung-Stafshede P, Björklund S.

Nucleic Acids Res. 2012 Jul;40(13):5938-50. doi: 10.1093/nar/gks265. Epub 2012 Mar 24.


Mechanisms of protein oligomerization: inhibitor of functional amyloids templates α-synuclein fibrillation.

Horvath I, Weise CF, Andersson EK, Chorell E, Sellstedt M, Bengtsson C, Olofsson A, Hultgren SJ, Chapman M, Wolf-Watz M, Almqvist F, Wittung-Stafshede P.

J Am Chem Soc. 2012 Feb 22;134(7):3439-44. doi: 10.1021/ja209829m. Epub 2012 Feb 9.


The efficacy of N-acetylcysteine to protect the human cochlea from subclinical hearing loss caused by impulse noise: a controlled trial.

Lindblad AC, Rosenhall U, Olofsson A, Hagerman B.

Noise Health. 2011 Nov-Dec;13(55):392-401. doi: 10.4103/1463-1741.90293.

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