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Items: 44

1.

Randomized, double-blind, Phase 1 trial of an alphavirus replicon vaccine for cytomegalovirus in CMV seronegative adult volunteers.

Bernstein DI, Reap EA, Katen K, Watson A, Smith K, Norberg P, Olmsted RA, Hoeper A, Morris J, Negri S, Maughan MF, Chulay JD.

Vaccine. 2009 Dec 11;28(2):484-93. doi: 10.1016/j.vaccine.2009.09.135. Epub 2009 Oct 24.

PMID:
19857446
2.

Development and preclinical evaluation of an alphavirus replicon particle vaccine for cytomegalovirus.

Reap EA, Morris J, Dryga SA, Maughan M, Talarico T, Esch RE, Negri S, Burnett B, Graham A, Olmsted RA, Chulay JD.

Vaccine. 2007 Oct 16;25(42):7441-9. Epub 2007 Aug 30.

3.

A novel alphavirus vaccine encoding prostate-specific membrane antigen elicits potent cellular and humoral immune responses.

Durso RJ, Andjelic S, Gardner JP, Margitich DJ, Donovan GP, Arrigale RR, Wang X, Maughan MF, Talarico TL, Olmsted RA, Heston WD, Maddon PJ, Olson WC.

Clin Cancer Res. 2007 Jul 1;13(13):3999-4008.

4.

Cellular and humoral immune responses to alphavirus replicon vaccines expressing cytomegalovirus pp65, IE1, and gB proteins.

Reap EA, Dryga SA, Morris J, Rivers B, Norberg PK, Olmsted RA, Chulay JD.

Clin Vaccine Immunol. 2007 Jun;14(6):748-55. Epub 2007 Apr 18.

5.

Synthesis and structure-activity relationships of the (alkylamino)piperidine-containing BHAP class of non-nucleoside reverse transcriptase inhibitors: effect of 3-alkylpyridine ring substitution.

Genin MJ, Poel TJ, May PD, Kopta LA, Yagi Y, Olmsted RA, Friis JM, Voorman RL, Adams WJ, Thomas RC, Romero DL.

J Med Chem. 1999 Oct 7;42(20):4140-9.

PMID:
10514284
6.

Pyrimidine thioethers: a novel class of HIV-1 reverse transcriptase inhibitors with activity against BHAP-resistant HIV.

Nugent RA, Schlachter ST, Murphy MJ, Cleek GJ, Poel TJ, Wishka DG, Graber DR, Yagi Y, Keiser BJ, Olmsted RA, Kopta LA, Swaney SM, Poppe SM, Morris J, Tarpley WG, Thomas RC.

J Med Chem. 1998 Sep 24;41(20):3793-803.

PMID:
9748354
7.

(-)-6-Chloro-2-[(1-furo[2, 3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor.

Wishka DG, Graber DR, Kopta LA, Olmsted RA, Friis JM, Hosley JD, Adams WJ, Seest EP, Castle TM, Dolak LA, Keiser BJ, Yagi Y, Jeganathan A, Schlachter ST, Murphy MJ, Cleek GJ, Nugent RA, Poppe SM, Swaney SM, Han F, Watt W, White WL, Poel TJ, Thomas RC, Morris J, et al.

J Med Chem. 1998 Apr 23;41(9):1357-60. No abstract available.

PMID:
9554867
8.

Synthesis and bioactivity of novel bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships and increased metabolic stability of novel substituted pyridine analogs.

Genin MJ, Poel TJ, Yagi Y, Biles C, Althaus I, Keiser BJ, Kopta LA, Friis JM, Reusser F, Adams WJ, Olmsted RA, Voorman RL, Thomas RC, Romero DL.

J Med Chem. 1996 Dec 20;39(26):5267-75.

PMID:
8978855
9.

Targeting delavirdine/atevirdine resistant HIV-1: identification of (alkylamino)piperidine-containing bis(heteroaryl)piperazines as broad spectrum HIV-1 reverse transcriptase inhibitors.

Romero DL, Olmsted RA, Poel TJ, Morge RA, Biles C, Keiser BJ, Kopta LA, Friis JM, Hosley JD, Stefanski KJ, Wishka DG, Evans DB, Morris J, Stehle RG, Sharma SK, Yagi Y, Voorman RL, Adams WJ, Tarpley WG, Thomas RC.

J Med Chem. 1996 Sep 13;39(19):3769-89.

PMID:
8809165
10.

A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation.

Fan N, Rank KB, Slade DE, Poppe SM, Evans DB, Kopta LA, Olmsted RA, Thomas RC, Tarpley WG, Sharma SK.

Biochemistry. 1996 Jul 30;35(30):9737-45.

PMID:
8703945
11.
12.

Nucleotide sequence analysis of puma lentivirus (PLV-14): genomic organization and relationship to other lentiviruses.

Langley RJ, Hirsch VM, O'Brien SJ, Adger-Johnson D, Goeken RM, Olmsted RA.

Virology. 1994 Aug 1;202(2):853-64.

PMID:
8030248
13.

Neurological abnormalities associated with feline immunodeficiency virus infection.

Phillips TR, Prospero-Garcia O, Puaoi DL, Lerner DL, Fox HS, Olmsted RA, Bloom FE, Henriksen SJ, Elder JH.

J Gen Virol. 1994 May;75 ( Pt 5):979-87.

PMID:
8176384
14.

Development of a novel subunit vaccine that protects cotton rats against both human respiratory syncytial virus and human parainfluenza virus type 3.

Homa FL, Brideau RJ, Lehman DJ, Thomsen DR, Olmsted RA, Wathen MW.

J Gen Virol. 1993 Sep;74 ( Pt 9):1995-9.

PMID:
8397289
15.

Experimental vaccine protection against homologous and heterologous strains of feline immunodeficiency virus.

Yamamoto JK, Hohdatsu T, Olmsted RA, Pu R, Louie H, Zochlinski HA, Acevedo V, Johnson HM, Soulds GA, Gardner MB.

J Virol. 1993 Jan;67(1):601-5.

16.

Worldwide prevalence of lentivirus infection in wild feline species: epidemiologic and phylogenetic aspects.

Olmsted RA, Langley R, Roelke ME, Goeken RM, Adger-Johnson D, Goff JP, Albert JP, Packer C, Laurenson MK, Caro TM, et al.

J Virol. 1992 Oct;66(10):6008-18.

17.

The small hydrophobic protein of human respiratory syncytial virus: comparison between antigenic subgroups A and B.

Collins PL, Olmsted RA, Johnson PR.

J Gen Virol. 1990 Jul;71 ( Pt 7):1571-6.

PMID:
2374008
18.

Primary pulmonary murine cytotoxic T lymphocyte specificity in respiratory syncytial virus pneumonia.

Gupta R, Yewdell JW, Olmsted RA, Collins PL, Bennink JR.

Microb Pathog. 1990 Jul;9(1):13-8.

PMID:
2077342
19.

Simian immunodeficiency viruses from African green monkeys display unusual genetic diversity.

Johnson PR, Fomsgaard A, Allan J, Gravell M, London WT, Olmsted RA, Hirsch VM.

J Virol. 1990 Mar;64(3):1086-92.

20.

Detection of SIV antigens by HIV-1 antigen capture immunoassays.

Goldstein S, Engle R, Olmsted RA, Hirsch VM, Johnson PR.

J Acquir Immune Defic Syndr. 1990;3(2):98-102.

PMID:
1688621
21.

Nucleotide sequence analysis of feline immunodeficiency virus: genome organization and relationship to other lentiviruses.

Olmsted RA, Hirsch VM, Purcell RH, Johnson PR.

Proc Natl Acad Sci U S A. 1989 Oct;86(20):8088-92.

22.

An African primate lentivirus (SIVsm) closely related to HIV-2.

Hirsch VM, Olmsted RA, Murphey-Corb M, Purcell RH, Johnson PR.

Nature. 1989 Jun 1;339(6223):389-92.

PMID:
2786147
24.

Molecular cloning of feline immunodeficiency virus.

Olmsted RA, Barnes AK, Yamamoto JK, Hirsch VM, Purcell RH, Johnson PR.

Proc Natl Acad Sci U S A. 1989 Apr;86(7):2448-52.

25.

Selective infection of human CD4+ cells by simian immunodeficiency virus: productive infection associated with envelope glycoprotein-induced fusion.

Koenig S, Hirsch VM, Olmsted RA, Powell D, Maury W, Rabson A, Fauci AS, Purcell RH, Johnson PR.

Proc Natl Acad Sci U S A. 1989 Apr;86(7):2443-7.

26.

Molecular cloning of SIV from sooty mangabey monkeys.

Hirsch VM, Dapolito G, McGann C, Olmsted RA, Purcell RH, Johnson PR.

J Med Primatol. 1989;18(3-4):279-85.

PMID:
2547963
27.

Genetic diversity among simian immunodeficiency virus isolates from African green monkeys.

Johnson PR, Gravell M, Allan J, Goldstein S, Olmsted RA, Dapolito G, McGann C, London WT, Purcell RH, Hirsch VM.

J Med Primatol. 1989;18(3-4):271-7.

PMID:
2547962
28.
29.

Evaluation in non-human primates of the safety, immunogenicity and efficacy of recombinant vaccinia viruses expressing the F or G glycoprotein of respiratory syncytial virus.

Olmsted RA, Buller RM, Collins PL, London WT, Beeler JA, Prince GA, Chanock RM, Murphy BR.

Vaccine. 1988 Dec;6(6):519-24.

PMID:
3072795
31.

Antibody-mediated activation of Sindbis virus.

Flynn DC, Olmsted RA, Mackenzie JM Jr, Johnston RE.

Virology. 1988 Sep;166(1):82-90.

PMID:
3413988
32.

Current approaches to the development of vaccines effective against parainfluenza and respiratory syncytial viruses.

Murphy BR, Prince GA, Collins PL, Van Wyke Coelingh K, Olmsted RA, Spriggs MK, Parrott RH, Kim HW, Brandt CD, Chanock RM.

Virus Res. 1988 Aug;11(1):1-15. Review.

PMID:
2845680
33.

Live viral vaccines for respiratory and enteric tract diseases.

Chanock RM, Murphy BR, Collins PL, Coelingh KV, Olmsted RA, Snyder MH, Spriggs MK, Prince GA, Moss B, Flores J, et al.

Vaccine. 1988 Apr;6(2):129-33. Review.

PMID:
2838984
35.
36.
37.

Gene overlap and site-specific attenuation of transcription of the viral polymerase L gene of human respiratory syncytial virus.

Collins PL, Olmsted RA, Spriggs MK, Johnson PR, Buckler-White AJ.

Proc Natl Acad Sci U S A. 1987 Aug;84(15):5134-8.

38.

Expression of the F glycoprotein of respiratory syncytial virus by a recombinant vaccinia virus: comparison of the individual contributions of the F and G glycoproteins to host immunity.

Olmsted RA, Elango N, Prince GA, Murphy BR, Johnson PR, Moss B, Chanock RM, Collins PL.

Proc Natl Acad Sci U S A. 1986 Oct;83(19):7462-6.

40.

A single nucleotide change in the E2 glycoprotein gene of Sindbis virus affects penetration rate in cell culture and virulence in neonatal mice.

Davis NL, Fuller FJ, Dougherty WG, Olmsted RA, Johnston RE.

Proc Natl Acad Sci U S A. 1986 Sep;83(18):6771-5.

41.

Fusion glycoprotein of human parainfluenza virus type 3: nucleotide sequence of the gene, direct identification of the cleavage-activation site, and comparison with other paramyxoviruses.

Spriggs MK, Olmsted RA, Venkatesan S, Coligan JE, Collins PL.

Virology. 1986 Jul 15;152(1):241-51. Erratum in: Virology 1987 May;158(1):263.

PMID:
3012869
42.

Nucleotide sequences for the gene junctions of human respiratory syncytial virus reveal distinctive features of intergenic structure and gene order.

Collins PL, Dickens LE, Buckler-White A, Olmsted RA, Spriggs MK, Camargo E, Coelingh KV.

Proc Natl Acad Sci U S A. 1986 Jul;83(13):4594-8.

43.
44.

Sindbis virus mutants selected for rapid growth in cell culture display attenuated virulence in animals.

Olmsted RA, Baric RS, Sawyer BA, Johnston RE.

Science. 1984 Jul 27;225(4660):424-7.

PMID:
6204381

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