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Items: 1 to 50 of 252

1.

Clinical practice guideline on atraumatic (pencil-point) vs conventional needles for lumbar puncture: Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine.

Rehn M, Chew MS, Olkkola KT, Sverrison KÖ, Yli-Hankala A, Møller MH.

Acta Anaesthesiol Scand. 2019 Apr;63(4):438-439. doi: 10.1111/aas.13312. Epub 2019 Jan 17. Review.

PMID:
30656651
2.

Prehospital National Early Warning Score predicts early mortality.

Pirneskoski J, Kuisma M, Olkkola KT, Nurmi J.

Acta Anaesthesiol Scand. 2019 May;63(5):676-683. doi: 10.1111/aas.13310. Epub 2019 Jan 8.

PMID:
30623422
3.

Randomised controlled study comparing general and spinal anaesthesia with and without a tourniquet on the outcomes of total knee arthroplasty: study protocol.

Rantasalo MT, Palanne R, Juutilainen K, Kairaluoma P, Linko R, Reponen E, Helkamaa T, Vakkuri A, Olkkola KT, Madanat R, Skants NKA.

BMJ Open. 2018 Dec 22;8(12):e025546. doi: 10.1136/bmjopen-2018-025546.

4.

Endorsement of clinical practice guidelines by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine.

Rehn M, Chew MS, Olkkola KT, Örn Sverrison K, Yli-Hankala A, Møller MH.

Acta Anaesthesiol Scand. 2019 Feb;63(2):161-163. doi: 10.1111/aas.13306. Epub 2018 Dec 3. Review.

PMID:
30511469
5.

Population pharmacokinetic modelling of intravenous paracetamol in fit older people displays extensive unexplained variability.

Mian P, van Esdonk MJ, Olkkola KT, de Winter BCM, Liukas A, Spriet I, Tibboel D, Petrovic M, Koch BCP, Allegaert K.

Br J Clin Pharmacol. 2019 Jan;85(1):126-135. doi: 10.1111/bcp.13770. Epub 2018 Oct 25.

PMID:
30321459
6.

Voriconazole greatly increases the exposure to oral buprenorphine.

Fihlman M, Hemmilä T, Hagelberg NM, Backman JT, Laitila J, Laine K, Neuvonen PJ, Olkkola KT, Saari TI.

Eur J Clin Pharmacol. 2018 Dec;74(12):1615-1622. doi: 10.1007/s00228-018-2548-8. Epub 2018 Aug 30.

PMID:
30167757
7.

Semimechanistic Population Pharmacokinetic Model to Predict the Drug-Drug Interaction Between S-ketamine and Ticlopidine in Healthy Human Volunteers.

Ashraf MW, Peltoniemi MA, Olkkola KT, Neuvonen PJ, Saari TI.

CPT Pharmacometrics Syst Pharmacol. 2018 Oct;7(10):687-697. doi: 10.1002/psp4.12346. Epub 2018 Sep 10.

8.

Investigation of drug-drug interactions and pain-From volunteer studies to randomized controlled trials in patients with chronic pain.

Olkkola KT, Hagelberg NM.

Scand J Pain. 2010 Jan 1;1(1):5. doi: 10.1016/j.sjpain.2009.09.002. No abstract available.

PMID:
29913931
9.

Opioids in emergency medicine - Are we treating pain adequately?

Kuusniemi KS, Olkkola KT.

Scand J Pain. 2011 Oct 1;2(4):185-186. doi: 10.1016/j.sjpain.2011.08.004. No abstract available.

PMID:
29913748
10.

Good quality of life before cardiac arrest predicts good quality of life after resuscitation.

Hellevuo H, Sainio M, Huhtala H, Olkkola KT, Tenhunen J, Hoppu S.

Acta Anaesthesiol Scand. 2018 Apr;62(4):515-521. doi: 10.1111/aas.13065. Epub 2018 Jan 7.

PMID:
29315466
11.

Body weight, gender and pregnancy affect enantiomer-specific ketorolac pharmacokinetics.

Välitalo PA, Kemppainen H, Kulo A, Smits A, van Calsteren K, Olkkola KT, de Hoon J, Knibbe CAJ, Allegaert K.

Br J Clin Pharmacol. 2017 Sep;83(9):1966-1975. doi: 10.1111/bcp.13311. Epub 2017 May 14.

12.

Maturation of Oxycodone Pharmacokinetics in Neonates and Infants: a Population Pharmacokinetic Model of Three Clinical Trials.

Välitalo P, Kokki M, Ranta VP, Olkkola KT, Hooker AC, Kokki H.

Pharm Res. 2017 May;34(5):1125-1133. doi: 10.1007/s11095-017-2122-6. Epub 2017 Feb 15.

PMID:
28205004
13.

Rifampicin decreases exposure to sublingual buprenorphine in healthy subjects.

Hagelberg NM, Fihlman M, Hemmilä T, Backman JT, Laitila J, Neuvonen PJ, Laine K, Olkkola KT, Saari TI.

Pharmacol Res Perspect. 2016 Nov 3;4(6):e00271. doi: 10.1002/prp2.271. eCollection 2016 Dec.

14.

Acute hormonal findings after aneurysmal subarachnoid hemorrhage - report from a single center.

Takala RS, Kiviranta R, Olkkola KT, Vahlberg T, Laukka D, Kotkansalo A, Rahi M, Sankinen M, Posti J, Katila A, Rinne J.

Endocr Res. 2017 May;42(2):125-131. doi: 10.1080/07435800.2016.1242603. Epub 2016 Oct 18.

PMID:
27754735
15.

Voriconazole more likely than posaconazole increases plasma exposure to sublingual buprenorphine causing a risk of a clinically important interaction.

Fihlman M, Hemmilä T, Hagelberg NM, Kuusniemi K, Backman JT, Laitila J, Laine K, Neuvonen PJ, Olkkola KT, Saari TI.

Eur J Clin Pharmacol. 2016 Nov;72(11):1363-1371. Epub 2016 Aug 10.

PMID:
27510521
16.

Aetiology of in-hospital cardiac arrest on general wards.

Tirkkonen J, Hellevuo H, Olkkola KT, Hoppu S.

Resuscitation. 2016 Oct;107:19-24. doi: 10.1016/j.resuscitation.2016.07.007. Epub 2016 Aug 1.

PMID:
27492850
17.

High-Dose Methylprednisolone Has No Benefit Over Moderate Dose for the Correction of Tetralogy of Fallot.

Keski-Nisula J, Pesonen E, Olkkola KT, Ahlroth T, Puntila J, Andersson S, Neuvonen PJ, Suominen PK.

Ann Thorac Surg. 2016 Sep;102(3):870-876. doi: 10.1016/j.athoracsur.2016.02.089. Epub 2016 May 4.

PMID:
27154159
18.

Ketamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy.

Peltoniemi MA, Hagelberg NM, Olkkola KT, Saari TI.

Clin Pharmacokinet. 2016 Sep;55(9):1059-77. doi: 10.1007/s40262-016-0383-6. Review.

PMID:
27028535
19.

Effect of Inhaled Xenon on Cerebral White Matter Damage in Comatose Survivors of Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial.

Laitio R, Hynninen M, Arola O, Virtanen S, Parkkola R, Saunavaara J, Roine RO, Grönlund J, Ylikoski E, Wennervirta J, Bäcklund M, Silvasti P, Nukarinen E, Tiainen M, Saraste A, Pietilä M, Airaksinen J, Valanne L, Martola J, Silvennoinen H, Scheinin H, Harjola VP, Niiranen J, Korpi K, Varpula M, Inkinen O, Olkkola KT, Maze M, Vahlberg T, Laitio T.

JAMA. 2016 Mar 15;315(11):1120-8. doi: 10.1001/jama.2016.1933.

20.

Aetiology of in-hospital cardiac arrest on general wards.

Tirkkonen J, Hellevuo H, Olkkola KT, Hoppu S.

Duodecim. 2016;132(18):1667. No abstract available.

PMID:
29188959
21.

Epidemiology and aetiology of impaired level of consciousness in prehospital nontrauma patients in an urban setting.

Björkman J, Hallikainen J, Olkkola KT, Silfvast T.

Eur J Emerg Med. 2016 Oct;23(5):375-80. doi: 10.1097/MEJ.0000000000000332.

PMID:
26426739
22.

Simultaneous beat-to-beat assessment of arterial blood pressure and quality of cardiopulmonary resuscitation in out-of-hospital and in-hospital settings.

Sainio M, Hoppu S, Huhtala H, Eilevstjønn J, Olkkola KT, Tenhunen J.

Resuscitation. 2015 Nov;96:163-9. doi: 10.1016/j.resuscitation.2015.08.004. Epub 2015 Aug 24.

PMID:
26310837
23.

[Amyotrophic lateral sclerosis and respiratory insufficiency].

Siirala W, Korpela J, Vuori A, Saaresranta T, Olkkola KT, Aantaa R.

Duodecim. 2015;131(2):127-35. Review. Finnish.

PMID:
26237914
24.

Mechanism-based population pharmacokinetic and pharmacodynamic modeling of intravenous and intranasal dexmedetomidine in healthy subjects.

Yoo H, Iirola T, Vilo S, Manner T, Aantaa R, Lahtinen M, Scheinin M, Olkkola KT, Jusko WJ.

Eur J Clin Pharmacol. 2015 Oct;71(10):1197-207. doi: 10.1007/s00228-015-1913-0. Epub 2015 Aug 2.

PMID:
26233335
25.

Ethically justified treatment limitations in emergency situations.

Tirkkonen J, Olkkola KT, Tenhunen J, Hoppu S.

Eur J Emerg Med. 2016 Jun;23(3):214-8. doi: 10.1097/MEJ.0000000000000240.

PMID:
25622183
26.

Effects of terbinafine and itraconazole on the pharmacokinetics of orally administered tramadol.

Saarikoski T, Saari TI, Hagelberg NM, Backman JT, Neuvonen PJ, Scheinin M, Olkkola KT, Laine K.

Eur J Clin Pharmacol. 2015 Mar;71(3):321-7. doi: 10.1007/s00228-014-1799-2. Epub 2015 Jan 6.

PMID:
25560051
27.

Effect of timing and route of methylprednisolone administration during pediatric cardiac surgical procedures.

Keski-Nisula J, Suominen PK, Olkkola KT, Peltola K, Neuvonen PJ, Tynkkynen P, Salminen JT, Andersson S, Pesonen E.

Ann Thorac Surg. 2015 Jan;99(1):180-5. doi: 10.1016/j.athoracsur.2014.08.042. Epub 2014 Nov 18.

PMID:
25440273
28.

Covariates of intravenous paracetamol pharmacokinetics in adults.

Allegaert K, Olkkola KT, Owens KH, Van de Velde M, de Maat MM, Anderson BJ; PACIA study group.

BMC Anesthesiol. 2014 Sep 13;14:77. doi: 10.1186/1471-2253-14-77. eCollection 2014.

29.

Neurocognitive long term follow-up study on drowned children.

Suominen PK, Sutinen N, Valle S, Olkkola KT, Lönnqvist T.

Resuscitation. 2014 Aug;85(8):1059-64. doi: 10.1016/j.resuscitation.2014.03.307. Epub 2014 Apr 4.

PMID:
24709615
30.

Effect of mattress and bed frame deflection on real chest compression depth measured with two CPR sensors.

Sainio M, Hellevuo H, Huhtala H, Hoppu S, Eilevstjønn J, Tenhunen J, Olkkola KT.

Resuscitation. 2014 Jun;85(6):840-3. doi: 10.1016/j.resuscitation.2014.03.009. Epub 2014 Mar 19.

PMID:
24657249
31.

Drowning in children: Utstein style reporting and outcome.

Vähätalo R, Lunetta P, Olkkola KT, Suominen PK.

Acta Anaesthesiol Scand. 2014 May;58(5):604-10. doi: 10.1111/aas.12298. Epub 2014 Mar 3.

PMID:
24580104
32.

Cardiac arrest teams and medical emergency teams in Finland: a nationwide cross-sectional postal survey.

Tirkkonen J, Nurmi J, Olkkola KT, Tenhunen J, Hoppu S.

Acta Anaesthesiol Scand. 2014 Apr;58(4):420-7. doi: 10.1111/aas.12280. Epub 2014 Feb 19.

PMID:
24571412
33.

Medical emergency team activation: performance of conventional dichotomised criteria versus national early warning score.

Tirkkonen J, Olkkola KT, Huhtala H, Tenhunen J, Hoppu S.

Acta Anaesthesiol Scand. 2014 Apr;58(4):411-9. doi: 10.1111/aas.12277. Epub 2014 Feb 12.

PMID:
24571384
34.

The quality of manual chest compressions during transport--effect of the mattress assessed by dual accelerometers.

Hellevuo H, Sainio M, Huhtala H, Olkkola KT, Tenhunen J, Hoppu S.

Acta Anaesthesiol Scand. 2014 Mar;58(3):323-8. doi: 10.1111/aas.12245. Epub 2013 Dec 26.

PMID:
24372080
35.

Feasibility and cardiac safety of inhaled xenon in combination with therapeutic hypothermia following out-of-hospital cardiac arrest.

Arola OJ, Laitio RM, Roine RO, Grönlund J, Saraste A, Pietilä M, Airaksinen J, Perttilä J, Scheinin H, Olkkola KT, Maze M, Laitio TT.

Crit Care Med. 2013 Sep;41(9):2116-24. doi: 10.1097/CCM.0b013e31828a4337.

PMID:
23896830
36.

Association of arterial blood pressure and CPR quality in a child using three different compression techniques, a case report.

Sainio M, Sutton RM, Huhtala H, Eilevstjønn J, Tenhunen J, Olkkola KT, Nadkarni VM, Hoppu S.

Scand J Trauma Resusc Emerg Med. 2013 Jul 2;21:51. doi: 10.1186/1757-7241-21-51.

37.

Real-time audiovisual feedback system in a physician-staffed helicopter emergency medical service in Finland: the quality results and barriers to implementation.

Sainio M, Kämäräinen A, Huhtala H, Aaltonen P, Tenhunen J, Olkkola KT, Hoppu S.

Scand J Trauma Resusc Emerg Med. 2013 Jul 1;21:50. doi: 10.1186/1757-7241-21-50.

38.

Is the effect of non-invasive ventilation on survival in amyotrophic lateral sclerosis age-dependent?

Siirala W, Aantaa R, Olkkola KT, Saaresranta T, Vuori A.

BMC Palliat Care. 2013 May 24;12:23. doi: 10.1186/1472-684X-12-23. eCollection 2013.

39.

A semiphysiological population pharmacokinetic model for dynamic inhibition of liver and gut wall cytochrome P450 3A by voriconazole.

Frechen S, Junge L, Saari TI, Suleiman AA, Rokitta D, Neuvonen PJ, Olkkola KT, Fuhr U.

Clin Pharmacokinet. 2013 Sep;52(9):763-81. doi: 10.1007/s40262-013-0070-9.

PMID:
23653047
40.

Methylprednisolone in neonatal cardiac surgery: reduced inflammation without improved clinical outcome.

Keski-Nisula J, Pesonen E, Olkkola KT, Peltola K, Neuvonen PJ, Tuominen N, Sairanen H, Andersson S, Suominen PK.

Ann Thorac Surg. 2013 Jun;95(6):2126-32. doi: 10.1016/j.athoracsur.2013.02.013. Epub 2013 Apr 18.

PMID:
23602068
41.

Deeper chest compression - more complications for cardiac arrest patients?

Hellevuo H, Sainio M, Nevalainen R, Huhtala H, Olkkola KT, Tenhunen J, Hoppu S.

Resuscitation. 2013 Jun;84(6):760-5. doi: 10.1016/j.resuscitation.2013.02.015. Epub 2013 Mar 5.

PMID:
23474390
42.

Does the pharmacology of oxycodone justify its increasing use as an analgesic?

Olkkola KT, Kontinen VK, Saari TI, Kalso EA.

Trends Pharmacol Sci. 2013 Apr;34(4):206-14. doi: 10.1016/j.tips.2013.02.001. Epub 2013 Mar 4. Review.

PMID:
23465410
43.

Using respiratory rate and thoracic movement to assess respiratory insufficiency in amyotrophic lateral sclerosis: a preliminary study.

Siirala W, Saaresranta T, Vuori A, Salanterä S, Olkkola KT, Aantaa R.

BMC Palliat Care. 2012 Dec 27;11:26. doi: 10.1186/1472-684X-11-26.

44.

Rifampicin markedly decreases the exposure to oral and intravenous tramadol.

Saarikoski T, Saari TI, Hagelberg NM, Neuvonen M, Neuvonen PJ, Scheinin M, Olkkola KT, Laine K.

Eur J Clin Pharmacol. 2013 Jun;69(6):1293-301. doi: 10.1007/s00228-012-1460-x. Epub 2012 Dec 15.

PMID:
23242004
45.

Response to Value of indirect calorimetry in non-invasive ventilation.

Siirala W, Noponen T, Olkkola KT, Vuori A, Koivisto M, Hurme S, Aantaa R.

J Clin Monit Comput. 2013 Feb;27(1):101-2. doi: 10.1007/s10877-012-9406-5. No abstract available.

PMID:
23192298
46.

Vital dysfunctions after intensive care discharge: prevalence and impact on patient outcome.

Tirkkonen J, Olkkola KT, Huhtala H, Tenhunen J, Hoppu S.

Acta Anaesthesiol Scand. 2013 Jan;57(1):56-62. doi: 10.1111/aas.12013. Epub 2012 Nov 21.

PMID:
23167302
47.

Ticlopidine inhibits both O-demethylation and renal clearance of tramadol, increasing the exposure to it, but itraconazole has no marked effect on the ticlopidine-tramadol interaction.

Hagelberg NM, Saarikoski T, Saari TI, Neuvonen M, Neuvonen PJ, Turpeinen M, Scheinin M, Laine K, Olkkola KT.

Eur J Clin Pharmacol. 2013 Apr;69(4):867-75. doi: 10.1007/s00228-012-1433-0. Epub 2012 Oct 26.

PMID:
23099620
48.

Factors associated with delayed activation of medical emergency team and excess mortality: an Utstein-style analysis.

Tirkkonen J, Ylä-Mattila J, Olkkola KT, Huhtala H, Tenhunen J, Hoppu S.

Resuscitation. 2013 Feb;84(2):173-8. doi: 10.1016/j.resuscitation.2012.09.021. Epub 2012 Sep 23.

PMID:
23009981
49.

Rifampicin has a profound effect on the pharmacokinetics of oral S-ketamine and less on intravenous S-ketamine.

Peltoniemi MA, Saari TI, Hagelberg NM, Laine K, Kurkinen KJ, Neuvonen PJ, Olkkola KT.

Basic Clin Pharmacol Toxicol. 2012 Nov;111(5):325-32. doi: 10.1111/j.1742-7843.2012.00908.x. Epub 2012 Jun 27.

50.

The effect of tepid amino acid-enriched induction cardioplegia on the outcome of infants undergoing cardiac surgery.

Suominen PK, Keski-Nisula J, Tynkkynen P, Kantoluoto S, Olkkola KT, Mildh L.

Perfusion. 2012 Jul;27(4):338-44. doi: 10.1177/0267659112442237. Epub 2012 Mar 21.

PMID:
22438222

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