Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 247

1.

Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies.

Chavarria D, Fernandes C, Silva V, Silva C, Gil-Martins E, Soares P, Silva T, Silva R, Remião F, Oliveira PJ, Borges F.

Eur J Med Chem. 2019 Oct 16:111770. doi: 10.1016/j.ejmech.2019.111770. [Epub ahead of print]

PMID:
31711793
2.

Bioisosteric OH- to SH-replacement changes the antioxidant profile of ferulic acid.

Chavarria D, Fernandes C, Silva T, Garrido J, Remião F, Oliveira PJ, Borges F.

Org Biomol Chem. 2019 Nov 28;17(44):9646-9654. doi: 10.1039/c9ob01875a. Epub 2019 Nov 1.

PMID:
31674614
3.

Transfer of Glucose Hydrogens via Acetyl-CoA, Malonyl-CoA and NADPH to Fatty Acids during de novo Lipogenesis.

Belew GD, Silva J, Rito J, Tavares L, Viegas I, Teixeira J, Oliveira PJ, Macedo MP, Jones JG.

J Lipid Res. 2019 Oct 1. pii: jlr.RA119000354. doi: 10.1194/jlr.RA119000354. [Epub ahead of print]

4.

Correspondence reply referring to the correspondence of Schirmer et al. (2019) received by Environmental Pollution regarding the publication Rodrigues et al. (2019).

Pardal MA, Oliveira PJ, Rodrigues ET.

Environ Pollut. 2019 Nov;254(Pt B):113059. doi: 10.1016/j.envpol.2019.113059. No abstract available.

PMID:
31540602
5.

A Mitochondrial Approach to Cardiovascular Risk and Disease.

Veloso CD, Belew GD, Ferreira LL, Grilo LF, Jones JG, Portincasa P, Sardão VA, Oliveira PJ.

Curr Pharm Des. 2019;25(29):3175-3194. doi: 10.2174/1389203720666190830163735.

PMID:
31470786
6.

Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver Disease.

Fontes A, Alemany-Pagès M, Oliveira PJ, Ramalho-Santos J, Zischka H, Azul AM.

Int J Mol Sci. 2019 Aug 16;20(16). pii: E3987. doi: 10.3390/ijms20163987. Review.

7.

Excess fructose and fatty acids trigger a model of non‑alcoholic fatty liver disease progression in vitro: Protective effect of the flavonoid silybin.

Grasselli E, Baldini F, Vecchione G, Oliveira PJ, Sardão VA, Voci A, Portincasa P, Vergani L.

Int J Mol Med. 2019 Aug;44(2):705-712. doi: 10.3892/ijmm.2019.4234. Epub 2019 Jun 6.

PMID:
31173180
8.

Physical exercise positively modulates DOX-induced hepatic oxidative stress, mitochondrial dysfunction and quality control signaling.

Santos-Alves E, Rizo-Roca D, Marques-Aleixo I, Coxito P, Martins S, Guimarães JT, Oliveira PJ, Torrella JR, Magalhães J, Ascensão A.

Mitochondrion. 2019 Jul;47:103-113. doi: 10.1016/j.mito.2019.05.008. Epub 2019 Jun 3.

PMID:
31170523
9.

Cell-based assays seem not to accurately predict fish short-term toxicity of pesticides.

Rodrigues ET, Varela AT, Pardal MA, Oliveira PJ.

Environ Pollut. 2019 Sep;252(Pt A):476-482. doi: 10.1016/j.envpol.2019.05.033. Epub 2019 May 27.

PMID:
31158675
10.

Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents.

Oliveira C, Bagetta D, Cagide F, Teixeira J, Amorim R, Silva T, Garrido J, Remião F, Uriarte E, Oliveira PJ, Alcaro S, Ortuso F, Borges F.

Eur J Med Chem. 2019 Jul 15;174:116-129. doi: 10.1016/j.ejmech.2019.04.026. Epub 2019 Apr 17.

11.

Cell quality control mechanisms maintain stemness and differentiation potential of P19 embryonic carcinoma cells.

Magalhães-Novais S, Bermejo-Millo JC, Loureiro R, Mesquita KA, Domingues MR, Maciel E, Melo T, Baldeiras I, Erickson JR, Holy J, Potes Y, Coto-Montes A, Oliveira PJ, Vega-Naredo I.

Autophagy. 2019 Apr 16:1-21. doi: 10.1080/15548627.2019.1607694. [Epub ahead of print]

PMID:
30990357
12.

Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction.

Benfeito S, Oliveira C, Fernandes C, Cagide F, Teixeira J, Amorim R, Garrido J, Martins C, Sarmento B, Silva R, Remião F, Uriarte E, Oliveira PJ, Borges F.

Eur J Med Chem. 2019 Apr 1;167:525-545. doi: 10.1016/j.ejmech.2019.01.055. Epub 2019 Feb 6.

PMID:
30784884
13.

Early Cardiac Mitochondrial Molecular and Functional Responses to Acute Anthracycline Treatment in Wistar Rats.

Pereira GC, Pereira SP, Pereira FB, Lourenço N, Lumini JA, Pereira CV, Bjork JA, Magalhães J, Ascensão A, Wieckowski MR, Moreno AJ, Wallace KB, Oliveira PJ.

Toxicol Sci. 2019 May 1;169(1):137-150. doi: 10.1093/toxsci/kfz026.

PMID:
30698778
14.

Single nanomolar doxorubicin exposure triggers compensatory mitochondrial responses in H9c2 cardiomyoblasts.

Ferreira LL, Cunha-Oliveira T, Veloso CD, Costa CF, Wallace KB, Oliveira PJ.

Food Chem Toxicol. 2019 Feb;124:450-461. doi: 10.1016/j.fct.2018.12.017. Epub 2018 Dec 14.

PMID:
30557669
15.

Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease.

Grattagliano I, Montezinho LP, Oliveira PJ, Frühbeck G, Gómez-Ambrosi J, Montecucco F, Carbone F, Wieckowski MR, Wang DQ, Portincasa P.

Biochem Pharmacol. 2019 Feb;160:34-45. doi: 10.1016/j.bcp.2018.11.020. Epub 2018 Nov 30. Review.

PMID:
30508523
16.

Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.

Bajzikova M, Kovarova J, Coelho AR, Boukalova S, Oh S, Rohlenova K, Svec D, Hubackova S, Endaya B, Judasova K, Bezawork-Geleta A, Kluckova K, Chatre L, Zobalova R, Novakova A, Vanova K, Ezrova Z, Maghzal GJ, Magalhaes Novais S, Olsinova M, Krobova L, An YJ, Davidova E, Nahacka Z, Sobol M, Cunha-Oliveira T, Sandoval-Acuña C, Strnad H, Zhang T, Huynh T, Serafim TL, Hozak P, Sardao VA, Koopman WJH, Ricchetti M, Oliveira PJ, Kolar F, Kubista M, Truksa J, Dvorakova-Hortova K, Pacak K, Gurlich R, Stocker R, Zhou Y, Berridge MV, Park S, Dong L, Rohlena J, Neuzil J.

Cell Metab. 2019 Feb 5;29(2):399-416.e10. doi: 10.1016/j.cmet.2018.10.014. Epub 2018 Nov 15.

PMID:
30449682
17.

Toxicity of lupane derivatives on anionic membrane models, isolated rat mitochondria and selected human cell lines: Role of terminal alkyl chains.

Carvalho FS, Morais CM, Holy J, Krasutsky D, Yemets SV, Krasutsky PA, Jurado AS, Oliveira PJ, Serafim TL.

Chem Biol Interact. 2018 Dec 25;296:198-210. doi: 10.1016/j.cbi.2018.10.002. Epub 2018 Oct 4.

PMID:
30292691
18.

Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors.

Reis J, Cagide F, Valencia ME, Teixeira J, Bagetta D, Pérez C, Uriarte E, Oliveira PJ, Ortuso F, Alcaro S, Rodríguez-Franco MI, Borges F.

Eur J Med Chem. 2018 Oct 5;158:781-800. doi: 10.1016/j.ejmech.2018.07.056. Epub 2018 Sep 11.

PMID:
30245401
19.

Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases.

Giorgi C, Marchi S, Simoes ICM, Ren Z, Morciano G, Perrone M, Patalas-Krawczyk P, Borchard S, Jędrak P, Pierzynowska K, Szymański J, Wang DQ, Portincasa P, Węgrzyn G, Zischka H, Dobrzyn P, Bonora M, Duszynski J, Rimessi A, Karkucinska-Wieckowska A, Dobrzyn A, Szabadkai G, Zavan B, Oliveira PJ, Sardao VA, Pinton P, Wieckowski MR.

Int Rev Cell Mol Biol. 2018;340:209-344. doi: 10.1016/bs.ircmb.2018.05.006. Epub 2018 Jun 22. Review.

PMID:
30072092
20.

Sources of hepatic glycogen synthesis in mice fed with glucose or fructose as the sole dietary carbohydrate.

Jarak I, Barosa C, Martins FO, Silva JCP, Santos C, Belew GD, Rito J, Viegas I, Teixeira J, Oliveira PJ, Jones JG.

Magn Reson Med. 2019 Jan;81(1):639-644. doi: 10.1002/mrm.27378. Epub 2018 Jul 29.

PMID:
30058123
21.

Desrisking the Cytotoxicity of a Mitochondriotropic Antioxidant Based on Caffeic Acid by a PEGylated Strategy.

Fernandes C, Benfeito S, Amorim R, Teixeira J, Oliveira PJ, Remião F, Borges F.

Bioconjug Chem. 2018 Aug 15;29(8):2723-2733. doi: 10.1021/acs.bioconjchem.8b00383. Epub 2018 Jul 18.

PMID:
29965741
22.

Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative Capacity.

Pereira SP, Deus CM, Serafim TL, Cunha-Oliveira T, Oliveira PJ.

Toxicol Sci. 2018 Jul 1;164(1):191-204. doi: 10.1093/toxsci/kfy068.

PMID:
29945227
23.

Electrochemical Behavior of a Mitochondria-Targeted Antioxidant at an Interface between Two Immiscible Electrolyte Solutions: An Alternative Approach to Study Lipophilicity.

Ribeiro JA, Benfeito S, Cagide F, Teixeira J, Oliveira PJ, Borges F, Silva AF, Pereira CM.

Anal Chem. 2018 Jul 3;90(13):7989-7996. doi: 10.1021/acs.analchem.8b00787. Epub 2018 Jun 12.

PMID:
29863846
24.

Evaluation of Respiration with Clark-Type Electrode in Isolated Mitochondria and Permeabilized Animal Cells.

Silva AM, Oliveira PJ.

Methods Mol Biol. 2018;1782:7-29. doi: 10.1007/978-1-4939-7831-1_2.

PMID:
29850992
25.

Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors.

Oliveira C, Cagide F, Teixeira J, Amorim R, Sequeira L, Mesiti F, Silva T, Garrido J, Remião F, Vilar S, Uriarte E, Oliveira PJ, Borges F.

Front Chem. 2018 Apr 23;6:126. doi: 10.3389/fchem.2018.00126. eCollection 2018.

26.

Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes.

Cunha-Oliveira T, Ferreira LL, Coelho AR, Deus CM, Oliveira PJ.

Toxicol Appl Pharmacol. 2018 Jun 1;348:1-13. doi: 10.1016/j.taap.2018.04.009. Epub 2018 Apr 11.

PMID:
29653124
27.

Development of a PEGylated-Based Platform for Efficient Delivery of Dietary Antioxidants Across the Blood-Brain Barrier.

Fernandes C, Pinto M, Martins C, Gomes MJ, Sarmento B, Oliveira PJ, Remião F, Borges F.

Bioconjug Chem. 2018 May 16;29(5):1677-1689. doi: 10.1021/acs.bioconjchem.8b00151. Epub 2018 Apr 19.

PMID:
29635917
28.

SULFATION PATHWAYS: Potential benefits of a sulfated resveratrol derivative for topical application.

Correia-da-Silva M, Rocha V, Marques C, Deus CM, Marques-Carvalho A, Oliveira PJ, Palmeira A, Pinto M, Sousa E, Sousa Lobo JM, Almeida IF.

J Mol Endocrinol. 2018 Aug;61(2):M27-M39. doi: 10.1530/JME-18-0031. Epub 2018 Mar 27.

PMID:
29588426
29.

Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid.

Teixeira J, Oliveira C, Cagide F, Amorim R, Garrido J, Borges F, Oliveira PJ.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):567-576. doi: 10.1080/14756366.2018.1442831.

30.

Mitochondria: Targeting mitochondrial reactive oxygen species with mitochondriotropic polyphenolic-based antioxidants.

Teixeira J, Deus CM, Borges F, Oliveira PJ.

Int J Biochem Cell Biol. 2018 Apr;97:98-103. doi: 10.1016/j.biocel.2018.02.007. Epub 2018 Feb 14. Review.

PMID:
29454114
31.

The beneficial role of exercise in mitigating doxorubicin-induced Mitochondrionopathy.

Marques-Aleixo I, Santos-Alves E, Oliveira PJ, Moreira PI, Magalhães J, Ascensão A.

Biochim Biophys Acta Rev Cancer. 2018 Apr;1869(2):189-199. doi: 10.1016/j.bbcan.2018.01.002. Epub 2018 Feb 14. Review.

PMID:
29408395
32.

TRAP1 regulates autophagy in lung cancer cells.

Barbosa IA, Vega-Naredo I, Loureiro R, Branco AF, Garcia R, Scott PM, Oliveira PJ.

Eur J Clin Invest. 2018 Apr;48(4). doi: 10.1111/eci.12900. Epub 2018 Feb 23.

PMID:
29383696
33.

Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cells.

Teixeira J, Basit F, Swarts HG, Forkink M, Oliveira PJ, Willems PHGM, Koopman WJH.

Redox Biol. 2018 May;15:394-404. doi: 10.1016/j.redox.2017.12.018. Epub 2017 Dec 30.

34.

Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative.

Teixeira J, Amorim R, Santos K, Soares P, Datta S, Cortopassi GA, Serafim TL, Sardão VA, Garrido J, Borges F, Oliveira PJ.

Toxicology. 2018 Jan 15;393:123-139. doi: 10.1016/j.tox.2017.11.014. Epub 2017 Nov 12.

PMID:
29141199
35.

The Nutraceutic Silybin Counteracts Excess Lipid Accumulation and Ongoing Oxidative Stress in an In Vitro Model of Non-Alcoholic Fatty Liver Disease Progression.

Vecchione G, Grasselli E, Cioffi F, Baldini F, Oliveira PJ, Sardão VA, Cortese K, Lanni A, Voci A, Portincasa P, Vergani L.

Front Nutr. 2017 Sep 19;4:42. doi: 10.3389/fnut.2017.00042. eCollection 2017.

36.

Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicity.

Ferreira A, Cunha-Oliveira T, Simões RF, Carvalho FS, Burgeiro A, Nordgren K, Wallace KB, Oliveira PJ.

Toxicology. 2017 Sep 1;390:63-73. doi: 10.1016/j.tox.2017.08.011. Epub 2017 Sep 1.

PMID:
28865727
37.

Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts.

Coelho AR, Martins TR, Couto R, Deus C, Pereira CV, Simões RF, Rizvanov AA, Silva F, Cunha-Oliveira T, Oliveira PJ, Serafim TL.

Biochim Biophys Acta Mol Basis Dis. 2017 Nov;1863(11):2904-2923. doi: 10.1016/j.bbadis.2017.07.030. Epub 2017 Jul 29.

38.

Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria.

Teixeira J, Oliveira C, Amorim R, Cagide F, Garrido J, Ribeiro JA, Pereira CM, Silva AF, Andrade PB, Oliveira PJ, Borges F.

Sci Rep. 2017 Jul 28;7(1):6842. doi: 10.1038/s41598-017-07272-y.

39.

Development of a Mitochondriotropic Antioxidant Based on Caffeic Acid: Proof of Concept on Cellular and Mitochondrial Oxidative Stress Models.

Teixeira J, Cagide F, Benfeito S, Soares P, Garrido J, Baldeiras I, Ribeiro JA, Pereira CM, Silva AF, Andrade PB, Oliveira PJ, Borges F.

J Med Chem. 2017 Aug 24;60(16):7084-7098. doi: 10.1021/acs.jmedchem.7b00741. Epub 2017 Aug 10.

PMID:
28745898
40.

Mitochondrial biology in cancer stem cells.

Loureiro R, Mesquita KA, Magalhães-Novais S, Oliveira PJ, Vega-Naredo I.

Semin Cancer Biol. 2017 Dec;47:18-28. doi: 10.1016/j.semcancer.2017.06.012. Epub 2017 Jun 30. Review.

PMID:
28673608
41.

Flexible nanofilms coated with aligned piezoelectric microfibers preserve the contractility of cardiomyocytes.

Gouveia PJ, Rosa S, Ricotti L, Abecasis B, Almeida HV, Monteiro L, Nunes J, Carvalho FS, Serra M, Luchkin S, Kholkin AL, Alves PM, Oliveira PJ, Carvalho R, Menciassi A, das Neves RP, Ferreira LS.

Biomaterials. 2017 Sep;139:213-228. doi: 10.1016/j.biomaterials.2017.05.048. Epub 2017 May 31.

42.

Guide of attributes of the nurse's political competence: a methodological study.

Melo WS, Oliveira PJF, Monteiro FPM, Santos FCDA, Silva MJND, Calderon CJ, Fonseca LNAD, Simão AAC.

Rev Bras Enferm. 2017 May-Jun;70(3):526-534. doi: 10.1590/0034-7167-2016-0483. English, Portuguese.

43.

Dietary Polyphenols and Mitochondrial Function: Role in Health and Disease.

Teixeira J, Chavarria D, Borges F, Wojtczak L, Wieckowski MR, Karkucinska-Wieckowska A, Oliveira PJ.

Curr Med Chem. 2019;26(19):3376-3406. doi: 10.2174/0929867324666170529101810.

PMID:
28554320
44.

Exercise and Doxorubicin Treatment Modulate Cardiac Mitochondrial Quality Control Signaling.

Marques-Aleixo I, Santos-Alves E, Torrella JR, Oliveira PJ, Magalhães J, Ascensão A.

Cardiovasc Toxicol. 2018 Feb;18(1):43-55. doi: 10.1007/s12012-017-9412-4.

PMID:
28536949
45.

Can health care providers recognise a fibromyalgia personality?

Da Silva JAP, Jacobs JWG, Branco JC, Canaipa R, Gaspar MF, Griep EN, van Helmond T, Oliveira PJ, Zijlstra TJ, Geenen R.

Clin Exp Rheumatol. 2017 May-Jun;35 Suppl 105(3):43-49. Epub 2017 Feb 23.

46.

Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells.

Dong LF, Kovarova J, Bajzikova M, Bezawork-Geleta A, Svec D, Endaya B, Sachaphibulkij K, Coelho AR, Sebkova N, Ruzickova A, Tan AS, Kluckova K, Judasova K, Zamecnikova K, Rychtarcikova Z, Gopalan V, Andera L, Sobol M, Yan B, Pattnaik B, Bhatraju N, Truksa J, Stopka P, Hozak P, Lam AK, Sedlacek R, Oliveira PJ, Kubista M, Agrawal A, Dvorakova-Hortova K, Rohlena J, Berridge MV, Neuzil J.

Elife. 2017 Feb 15;6. pii: e22187. doi: 10.7554/eLife.22187.

47.

Protective Effect of Green Tea (Camellia sinensis (L.) Kuntze) against Prostate Cancer: From In Vitro Data to Algerian Patients.

Lassed S, Deus CM, Djebbari R, Zama D, Oliveira PJ, Rizvanov AA, Dahdouh A, Benayache F, Benayache S.

Evid Based Complement Alternat Med. 2017;2017:1691568. doi: 10.1155/2017/1691568. Epub 2017 Jan 4.

48.

Evaluation of biological properties of 3,3',4,4'-benzophenonetetracarboxylic dianhydride derivatives and their ability to inhibit hexokinase activity.

Kochel K, Tomczyk MD, Simões RF, Frączek T, Soboń A, Oliveira PJ, Walczak KZ, Koceva-Chyła A.

Bioorg Med Chem Lett. 2017 Feb 1;27(3):427-431. doi: 10.1016/j.bmcl.2016.12.055. Epub 2016 Dec 25.

PMID:
28063798
49.

Hematopoietic and Mesenchymal Stem Cells in Biomedical and Clinical Applications.

Rizvanov AA, Persson J, Şahin F, Bellusci S, Oliveira PJ.

Stem Cells Int. 2016;2016:3157365. doi: 10.1155/2016/3157365. Epub 2016 Nov 24. No abstract available.

50.

Diet, Lifestyles, Family History, and Prostate Cancer Incidence in an East Algerian Patient Group.

Lassed S, Deus CM, Lourenço N, Dahdouh A, Rizvanov AA, Oliveira PJ, Zama D.

Biomed Res Int. 2016;2016:5730569. Epub 2016 Oct 19.

Supplemental Content

Loading ...
Support Center