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Items: 26


A gain-of-function RAC2 mutation is associated with bone-marrow hypoplasia and an autosomal dominant form of severe combined immunodeficiency.

Lagresle-Peyrou C, Olichon A, Sadek H, Roche P, Tardy C, Da Silva C, Garrigue A, Fischer A, Moshous D, Collette Y, Picard C, Casanova JL, André I, Cavazzana M.

Haematologica. 2020 Jan 9. pii: haematol.2019.230250. doi: 10.3324/haematol.2019.230250. [Epub ahead of print]


Selection and Characterization of a Nanobody Biosensor of GTP-Bound RHO Activities.

Keller L, Bery N, Tardy C, Ligat L, Favre G, Rabbitts TH, Olichon A.

Antibodies (Basel). 2019 Jan 9;8(1). pii: E8. doi: 10.3390/antib8010008.


A Targeted Protein Degradation Cell-Based Screening for Nanobodies Selective toward the Cellular RHOB GTP-Bound Conformation.

Bery N, Keller L, Soulié M, Gence R, Iscache AL, Cherier J, Cabantous S, Sordet O, Lajoie-Mazenc I, Pedelacq JD, Favre G, Olichon A.

Cell Chem Biol. 2019 Nov 21;26(11):1544-1558.e6. doi: 10.1016/j.chembiol.2019.08.009. Epub 2019 Sep 12.


Nanobodies reveal an extra-synaptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons.

Maidorn M, Olichon A, Rizzoli SO, Opazo F.

MAbs. 2019 Feb/Mar;11(2):305-321. doi: 10.1080/19420862.2018.1551675. Epub 2018 Dec 28.


NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies.

Moutel S, Bery N, Bernard V, Keller L, Lemesre E, de Marco A, Ligat L, Rain JC, Favre G, Olichon A, Perez F.

Elife. 2016 Jul 19;5. pii: e16228. doi: 10.7554/eLife.16228.


Chromatibody, a novel non-invasive molecular tool to explore and manipulate chromatin in living cells.

Jullien D, Vignard J, Fedor Y, Béry N, Olichon A, Crozatier M, Erard M, Cassard H, Ducommun B, Salles B, Mirey G.

J Cell Sci. 2016 Jul 1;129(13):2673-83. doi: 10.1242/jcs.183103. Epub 2016 May 20.


Generation of a single chain antibody variable fragment (scFv) to sense selectively RhoB activation.

Chinestra P, Olichon A, Medale-Giamarchi C, Lajoie-Mazenc I, Gence R, Inard C, Ligat L, Faye JC, Favre G.

PLoS One. 2014 Nov 3;9(11):e111034. doi: 10.1371/journal.pone.0111034. eCollection 2014.


Preparation of a naïve library of camelid single domain antibodies.

Olichon A, de Marco A.

Methods Mol Biol. 2012;911:65-78. doi: 10.1007/978-1-61779-968-6_5.


Single domain antibodies with VH hallmarks are positively selected during panning of llama (Lama glama) naïve libraries.

Monegal A, Olichon A, Bery N, Filleron T, Favre G, de Marco A.

Dev Comp Immunol. 2012 Jan;36(1):150-6. doi: 10.1016/j.dci.2011.06.016. Epub 2011 Jul 13.


OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution.

Elachouri G, Vidoni S, Zanna C, Pattyn A, Boukhaddaoui H, Gaget K, Yu-Wai-Man P, Gasparre G, Sarzi E, Delettre C, Olichon A, Loiseau D, Reynier P, Chinnery PF, Rotig A, Carelli V, Hamel CP, Rugolo M, Lenaers G.

Genome Res. 2011 Jan;21(1):12-20. doi: 10.1101/gr.108696.110. Epub 2010 Oct 25.


OPA1 (dys)functions.

Landes T, Leroy I, Bertholet A, Diot A, Khosrobakhsh F, Daloyau M, Davezac N, Miquel MC, Courilleau D, Guillou E, Olichon A, Lenaers G, Arnauné-Pelloquin L, Emorine LJ, Belenguer P.

Semin Cell Dev Biol. 2010 Aug;21(6):593-8. doi: 10.1016/j.semcdb.2009.12.012. Epub 2010 Jan 4. Review.


OPA1 functions in mitochondria and dysfunctions in optic nerve.

Lenaers G, Reynier P, Elachouri G, Soukkarieh C, Olichon A, Belenguer P, Baricault L, Ducommun B, Hamel C, Delettre C.

Int J Biochem Cell Biol. 2009 Oct;41(10):1866-74. doi: 10.1016/j.biocel.2009.04.013. Epub 2009 Apr 21. Review.


Phosphorylation by Cdk1 increases the binding of Eg5 to microtubules in vitro and in Xenopus egg extract spindles.

Cahu J, Olichon A, Hentrich C, Schek H, Drinjakovic J, Zhang C, Doherty-Kirby A, Lajoie G, Surrey T.

PLoS One. 2008;3(12):e3936. doi: 10.1371/journal.pone.0003936. Epub 2008 Dec 15.


Llama-derived single-chain antibody fragments directed to rotavirus VP6 protein possess broad neutralizing activity in vitro and confer protection against diarrhea in mice.

Garaicoechea L, Olichon A, Marcoppido G, Wigdorovitz A, Mozgovoj M, Saif L, Surrey T, Parreño V.

J Virol. 2008 Oct;82(19):9753-64. doi: 10.1128/JVI.00436-08. Epub 2008 Jul 16.


OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals.

Baricault L, Ségui B, Guégand L, Olichon A, Valette A, Larminat F, Lenaers G.

Exp Cell Res. 2007 Oct 15;313(17):3800-8. Epub 2007 Aug 19.


Heating as a rapid purification method for recovering correctly-folded thermotolerant VH and VHH domains.

Olichon A, Schweizer D, Muyldermans S, de Marco A.

BMC Biotechnol. 2007 Jan 26;7:7.


Effects of OPA1 mutations on mitochondrial morphology and apoptosis: relevance to ADOA pathogenesis.

Olichon A, Landes T, Arnauné-Pelloquin L, Emorine LJ, Mils V, Guichet A, Delettre C, Hamel C, Amati-Bonneau P, Bonneau D, Reynier P, Lenaers G, Belenguer P.

J Cell Physiol. 2007 May;211(2):423-30.


OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis.

Olichon A, Elachouri G, Baricault L, Delettre C, Belenguer P, Lenaers G.

Cell Death Differ. 2007 Apr;14(4):682-92. Epub 2006 Oct 6.


Mitochondrial dynamics and disease, OPA1.

Olichon A, Guillou E, Delettre C, Landes T, Arnauné-Pelloquin L, Emorine LJ, Mils V, Daloyau M, Hamel C, Amati-Bonneau P, Bonneau D, Reynier P, Lenaers G, Belenguer P.

Biochim Biophys Acta. 2006 May-Jun;1763(5-6):500-9. Epub 2006 Apr 20. Review.


Expression of the Opa1 mitochondrial protein in retinal ganglion cells: its downregulation causes aggregation of the mitochondrial network.

Kamei S, Chen-Kuo-Chang M, Cazevieille C, Lenaers G, Olichon A, Bélenguer P, Roussignol G, Renard N, Eybalin M, Michelin A, Delettre C, Brabet P, Hamel CP.

Invest Ophthalmol Vis Sci. 2005 Nov;46(11):4288-94.


OPA1 R445H mutation in optic atrophy associated with sensorineural deafness.

Amati-Bonneau P, Guichet A, Olichon A, Chevrollier A, Viala F, Miot S, Ayuso C, Odent S, Arrouet C, Verny C, Calmels MN, Simard G, Belenguer P, Wang J, Puel JL, Hamel C, Malthièry Y, Bonneau D, Lenaers G, Reynier P.

Ann Neurol. 2005 Dec;58(6):958-63.


OPA3 gene mutations responsible for autosomal dominant optic atrophy and cataract.

Reynier P, Amati-Bonneau P, Verny C, Olichon A, Simard G, Guichet A, Bonnemains C, Malecaze F, Malinge MC, Pelletier JB, Calvas P, Dollfus H, Belenguer P, Malthièry Y, Lenaers G, Bonneau D.

J Med Genet. 2004 Sep;41(9):e110. No abstract available.


Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis.

Olichon A, Baricault L, Gas N, Guillou E, Valette A, Belenguer P, Lenaers G.

J Biol Chem. 2003 Mar 7;278(10):7743-6. Epub 2002 Dec 31.


What similarity between human and fission yeast proteins is required for orthology?

Lenaers G, Pelloquin L, Olichon A, Emorine LJ, Guillou E, Delettre C, Hamel CP, Ducommun B, Belenguer P.

Yeast. 2002 Sep 30;19(13):1125-6. No abstract available.


The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space.

Olichon A, Emorine LJ, Descoins E, Pelloquin L, Brichese L, Gas N, Guillou E, Delettre C, Valette A, Hamel CP, Ducommun B, Lenaers G, Belenguer P.

FEBS Lett. 2002 Jul 17;523(1-3):171-6.

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