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Items: 11


High chromosome number in hematological cancer cell lines is a negative predictor of response to the inhibition of Aurora B and C by GSK1070916.

Moy C, Oleykowski CA, Plant R, Greshock J, Jing J, Bachman K, Hardwicke MA, Wooster R, Degenhardt Y.

J Transl Med. 2011 Jul 15;9:110. doi: 10.1186/1479-5876-9-110.


Discovery of GSK1070916, a potent and selective inhibitor of Aurora B/C kinase.

Adams ND, Adams JL, Burgess JL, Chaudhari AM, Copeland RA, Donatelli CA, Drewry DH, Fisher KE, Hamajima T, Hardwicke MA, Huffman WF, Koretke-Brown KK, Lai ZV, McDonald OB, Nakamura H, Newlander KA, Oleykowski CA, Parrish CA, Patrick DR, Plant R, Sarpong MA, Sasaki K, Schmidt SJ, Silva DJ, Sutton D, Tang J, Thompson CS, Tummino PJ, Wang JC, Xiang H, Yang J, Dhanak D.

J Med Chem. 2010 May 27;53(10):3973-4001. doi: 10.1021/jm901870q.


Discovery of a new series of Aurora inhibitors through truncation of GSK1070916.

Medina JR, Grant SW, Axten JM, Miller WH, Donatelli CA, Hardwicke MA, Oleykowski CA, Liao Q, Plant R, Xiang H.

Bioorg Med Chem Lett. 2010 Apr 15;20(8):2552-5. doi: 10.1016/j.bmcl.2010.02.091. Epub 2010 Mar 1.


GSK1070916, a potent Aurora B/C kinase inhibitor with broad antitumor activity in tissue culture cells and human tumor xenograft models.

Hardwicke MA, Oleykowski CA, Plant R, Wang J, Liao Q, Moss K, Newlander K, Adams JL, Dhanak D, Yang J, Lai Z, Sutton D, Patrick D.

Mol Cancer Ther. 2009 Jul;8(7):1808-17. doi: 10.1158/1535-7163.MCT-09-0041. Epub 2009 Jun 30.


Characterization of a periplasmic S1-like nuclease coded by the Mesorhizobium loti symbiosis island.

Pimkin M, Miller CG, Blakesley L, Oleykowski CA, Kodali NS, Yeung AT.

Biochem Biophys Res Commun. 2006 Apr 28;343(1):77-84. Epub 2006 Feb 28.


Detection of simple mutations and polymorphisms in large genomic regions.

Sokurenko EV, Tchesnokova V, Yeung AT, Oleykowski CA, Trintchina E, Hughes KT, Rashid RA, Brint JM, Moseley SL, Lory S.

Nucleic Acids Res. 2001 Nov 15;29(22):E111.


CEL I enzymatic mutation detection assay.

Kulinski J, Besack D, Oleykowski CA, Godwin AK, Yeung AT.

Biotechniques. 2000 Jul;29(1):44-6, 48. No abstract available.


Purification, cloning, and characterization of the CEL I nuclease.

Yang B, Wen X, Kodali NS, Oleykowski CA, Miller CG, Kulinski J, Besack D, Yeung JA, Kowalski D, Yeung AT.

Biochemistry. 2000 Apr 4;39(13):3533-41.


Incision at nucleotide insertions/deletions and base pair mismatches by the SP nuclease of spinach.

Oleykowski CA, Bronson Mullins CR, Chang DW, Yeung AT.

Biochemistry. 1999 Feb 16;38(7):2200-5.


Mutation detection using a novel plant endonuclease.

Oleykowski CA, Bronson Mullins CR, Godwin AK, Yeung AT.

Nucleic Acids Res. 1998 Oct 15;26(20):4597-602.


Repair of aflatoxin B1 DNA adducts by the UvrABC endonuclease of Escherichia coli.

Oleykowski CA, Mayernik JA, Lim SE, Groopman JD, Grossman L, Wogan GN, Yeung AT.

J Biol Chem. 1993 Apr 15;268(11):7990-8002.

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