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Items: 1 to 50 of 88

1.

Gastrointestinal pain.

Drewes AM, Olesen AE, Farmer AD, Szigethy E, Rebours V, Olesen SS.

Nat Rev Dis Primers. 2020 Jan 6;6(1):1. doi: 10.1038/s41572-019-0135-7. Review.

PMID:
31907359
2.

Chronic abdominal pain and persistent opioid use after bariatric surgery.

Simoni AH, Ladebo L, Christrup LL, Drewes AM, Johnsen SP, Olesen AE.

Scand J Pain. 2019 Nov 22. pii: /j/sjpain.ahead-of-print/sjpain-2019-0092/sjpain-2019-0092.xml. doi: 10.1515/sjpain-2019-0092. [Epub ahead of print]

PMID:
31756166
3.

Analyzing and Benchmarking Global Consumption Statistics for Opioid Analgesics 2015: Inequality Continues to Increase.

Scholten W, Christensen AE, Olesen AE, Drewes AM.

J Pain Palliat Care Pharmacother. 2020 Mar;34(1):1-12. doi: 10.1080/15360288.2019.1686098. Epub 2019 Nov 22.

PMID:
31755794
4.

Correction: Predictors of opioid efficacy in patients with chronic pain: A prospective multicenter observational cohort study.

Grosen K, Olesen AE, Gram M, Jonsson T, Kamp-Jensen M, Andresen T, Nielsen C, Pozlep G, Pfeiffer-Jensen M, Morlion B, Drewes AM.

PLoS One. 2019 Oct 30;14(10):e0224779. doi: 10.1371/journal.pone.0224779. eCollection 2019.

5.

Population pharmacokinetic-pharmacodynamic modelling of liquid and controlled-release formulations of oxycodone in healthy volunteers.

Ladebo L, Foster DJR, Abuhelwa AY, Upton RN, Kongstad KT, Drewes AM, Christrup LL, Olesen AE.

Basic Clin Pharmacol Toxicol. 2020 Mar;126(3):263-276. doi: 10.1111/bcpt.13330. Epub 2019 Oct 28.

PMID:
31597014
6.

Effects of Naloxegol on Gastrointestinal Transit and Colonic Fecal Volume in Healthy Participants Receiving Oxycodone.

Olesen AE, Grønlund D, Mark EB, Krogh K, Frøkjær JB, Drewes AM.

J Neurogastroenterol Motil. 2019 Oct 30;25(4):602-610. doi: 10.5056/jnm18079.

7.

Pain inhibitory mechanisms and response to weak analgesics in patients with knee osteoarthritis.

Petersen KK, Simonsen O, Olesen AE, Mørch CD, Arendt-Nielsen L.

Eur J Pain. 2019 Nov;23(10):1904-1912. doi: 10.1002/ejp.1465. Epub 2019 Aug 19.

PMID:
31376308
8.

Patient and Disease Characteristics Associate With Sensory Testing Results in Chronic Pancreatitis.

Kuhlmann L, Olesen SS, Grønlund D, Olesen AE, Phillips AE, Faghih M, Drewes AM.

Clin J Pain. 2019 Sep;35(9):786-793. doi: 10.1097/AJP.0000000000000740.

9.

Pathophysiology and management of diabetic gastroenteropathy.

Meldgaard T, Keller J, Olesen AE, Olesen SS, Krogh K, Borre M, Farmer A, Brock B, Brock C, Drewes AM.

Therap Adv Gastroenterol. 2019 Jun 17;12:1756284819852047. doi: 10.1177/1756284819852047. eCollection 2019. Review.

10.

Opioid use after hip fracture surgery: A Danish nationwide cohort study from 2005 to 2015.

Simoni AH, Nikolajsen L, Olesen AE, Christiansen CF, Pedersen AB.

Eur J Pain. 2019 Aug;23(7):1309-1317. doi: 10.1002/ejp.1392. Epub 2019 Mar 25.

PMID:
30848038
11.

Mechanism-based pain management in chronic pancreatitis - is it time for a paradigm shift?

Kuhlmann L, Olesen SS, Olesen AE, Arendt-Nielsen L, Drewes AM.

Expert Rev Clin Pharmacol. 2019 Mar;12(3):249-258. doi: 10.1080/17512433.2019.1571409. Epub 2019 Feb 5. Review.

PMID:
30664364
12.

Quantifying the Adequacy of Opioid Analgesic Consumption Globally: An Updated Method and Early Findings.

Scholten WK, Christensen AE, Olesen AE, Drewes AM.

Am J Public Health. 2019 Jan;109(1):52-57. doi: 10.2105/AJPH.2018.304753. Epub 2018 Nov 29.

13.

A Pragmatic Utility Function to Describe the Risk-Benefit Composite of Opioid and Nonopioid Analgesic Medication.

Olesen AE, Broens S, Olesen SS, Niesters M, van Velzen M, Drewes AM, Dahan A, Olofsen E.

J Pharmacol Exp Ther. 2019 Nov;371(2):416-421. doi: 10.1124/jpet.118.253716. Epub 2018 Nov 15.

PMID:
30442653
14.

Mechanistic pain profiling as a tool to predict the efficacy of 3-week nonsteroidal anti-inflammatory drugs plus paracetamol in patients with painful knee osteoarthritis.

Petersen KK, Olesen AE, Simonsen O, Arendt-Nielsen L.

Pain. 2019 Feb;160(2):486-492. doi: 10.1097/j.pain.0000000000001427.

PMID:
30371559
15.

Offset analgesia is not affected by cold pressor induced analgesia.

Nissen TD, Mørch CD, Arendt-Nielsen L, Drewes AM, Olesen AE.

Scand J Pain. 2018 Oct 25;18(4):695-701. doi: 10.1515/sjpain-2018-0082.

PMID:
30307901
16.

Comparison of subjective and objective measures of constipation - Employing a new method for categorizing gastrointestinal symptoms.

Grønlund D, Vase L, Knudsen SA, Christensen M, Drewes AM, Olesen AE.

J Pharmacol Toxicol Methods. 2018 Nov - Dec;94(Pt 2):23-28. doi: 10.1016/j.vascn.2018.08.002. Epub 2018 Aug 24.

PMID:
30149126
17.

[Opioid dependency as complication after surgery].

Uhrbrand P, Simoni AH, Olesen AE, Pedersen AB, Christiansen CF, Nikolajsen L.

Ugeskr Laeger. 2018 Jul 30;180(31). pii: V01180083. Review. Danish.

PMID:
30064619
18.

Offset Analgesia and The Impact of Treatment with Oxycodone and Venlafaxine: A Placebo-Controlled, Randomized Trial in Healthy Volunteers.

Olesen AE, Nissen TD, Nilsson M, Lelic D, Brock C, Christrup LL, Drewes AM.

Basic Clin Pharmacol Toxicol. 2018 Dec;123(6):727-731. doi: 10.1111/bcpt.13078. Epub 2018 Jul 31.

19.

Somatosensory and trophic findings in the referred pain area in patients with kidney stone disease.

Pedersen KV, Drewes AM, Graumann O, Osther SS, Olesen AE, Arendt-Nielsen L, Sloth Osther PJ.

Scand J Pain. 2013 Jul 1;4(3):165-170. doi: 10.1016/j.sjpain.2013.03.001.

PMID:
29913913
20.

The Effect of a Combination of Diclofenac and Methadone Applied as Gel in a Human Experimental Pain Model - A Randomized, Placebo-controlled Trial.

Larsen IM, Drewes AM, Olesen AE.

Basic Clin Pharmacol Toxicol. 2018 Aug;123(2):188-194. doi: 10.1111/bcpt.12993. Epub 2018 Apr 15.

21.

Differential effects of oxycodone and venlafaxine on resting state functional connectivity-A randomized placebo-controlled magnetic resonance imaging study.

Hansen TM, Lelic D, Olesen AE, Drewes AM, Frøkjaer JB.

CNS Neurosci Ther. 2018 Sep;24(9):820-827. doi: 10.1111/cns.12827. Epub 2018 Feb 21.

22.

The impact of naloxegol on anal sphincter function - Using a human experimental model of opioid-induced bowel dysfunction.

Grønlund D, Poulsen JL, Krogh K, Brock C, Liao D, Gregersen H, Drewes AM, Olesen AE.

Eur J Pharm Sci. 2018 May 30;117:187-192. doi: 10.1016/j.ejps.2018.02.008. Epub 2018 Feb 9.

PMID:
29432808
23.

Prediction of opioid dose in cancer pain patients using genetic profiling: not yet an option with support vector machine learning.

Olesen AE, Grønlund D, Gram M, Skorpen F, Drewes AM, Klepstad P.

BMC Res Notes. 2018 Jan 27;11(1):78. doi: 10.1186/s13104-018-3194-z.

24.

Do genes affect morphine response?

Ladebo L, Olesen AE.

Pharmacogenomics. 2017 Nov;18(17):1553-1555. doi: 10.2217/pgs-2017-0138. Epub 2017 Oct 24. No abstract available.

25.

Association Between Genetic Polymorphisms and Pain Sensitivity in Patients with Hip Osteoarthritis.

Olesen AE, Nielsen LM, Feddersen S, Erlenwein J, Petzke F, Przemeck M, Christrup LL, Drewes AM.

Pain Pract. 2018 Jun;18(5):587-596. doi: 10.1111/papr.12648. Epub 2017 Nov 30.

PMID:
29055075
26.

Objective methods for the assessment of the spinal and supraspinal effects of opioids.

Fischer IW, Hansen TM, Lelic D, Brokjaer A, Frøkjær J, Christrup LL, Olesen AE.

Scand J Pain. 2017 Jan;14:15-24. doi: 10.1016/j.sjpain.2016.10.001. Epub 2016 Nov 1. Review.

27.

The effects of analgesics on central processing of tonic pain: A cross-over placebo controlled study.

Lelic D, Hansen TM, Mark EB, Olesen AE, Drewes AM.

Neuropharmacology. 2017 Sep 1;123:455-464. doi: 10.1016/j.neuropharm.2017.06.022. Epub 2017 Jun 22.

PMID:
28648913
28.

Predictors of opioid efficacy in patients with chronic pain: A prospective multicenter observational cohort study.

Grosen K, Olesen AE, Gram M, Jonsson T, Kamp-Jensen M, Andresen T, Nielsen C, Pozlep G, Pfeiffer-Jensen M, Morlion B, Drewes AM.

PLoS One. 2017 Feb 3;12(2):e0171723. doi: 10.1371/journal.pone.0171723. eCollection 2017. Erratum in: PLoS One. 2019 Oct 30;14(10):e0224779.

29.

Established and emerging methods for assessment of small and large intestinal motility.

Grønlund D, Poulsen JL, Sandberg TH, Olesen AE, Madzak A, Krogh K, Frøkjaer JB, Drewes AM.

Neurogastroenterol Motil. 2017 Jul;29(7). doi: 10.1111/nmo.13008. Epub 2017 Jan 13. Review.

PMID:
28086261
30.

Genetic Influences of OPRM1, OPRD1 and COMT on Morphine Analgesia in a Multi-Modal, Multi-Tissue Human Experimental Pain Model.

Nielsen LM, Christrup LL, Sato H, Drewes AM, Olesen AE.

Basic Clin Pharmacol Toxicol. 2017 Jul;121(1):6-12. doi: 10.1111/bcpt.12757. Epub 2017 Mar 14.

31.

Lack of genetic association between OCT1, ABCB1, and UGT2B7 variants and morphine pharmacokinetics.

Nielsen LM, Sverrisdóttir E, Stage TB, Feddersen S, Brøsen K, Christrup LL, Drewes AM, Olesen AE.

Eur J Pharm Sci. 2017 Mar 1;99:337-342. doi: 10.1016/j.ejps.2016.12.039. Epub 2017 Jan 4.

PMID:
28063968
32.

Cortical and spinal assessment - a comparative study using encephalography and the nociceptive withdrawal reflex.

Fischer IW, Gram M, Hansen TM, Brokjaer A, Graversen C, Malver LP, Mørch CD, Christrup LL, Drewes AM, Olesen AE.

J Pharmacol Toxicol Methods. 2017 Mar - Apr;84:37-43. doi: 10.1016/j.vascn.2016.10.008. Epub 2016 Oct 29.

PMID:
27989852
33.

Venlafaxine and oxycodone effects on human spinal and supraspinal pain processing: a randomized cross-over trial.

Lelic D, Fischer IW, Olesen AE, Mørch CD, Arguissain FG, Manresa JA, Dahan A, Drewes AM.

Eur J Neurosci. 2016 Dec;44(11):2966-2974. doi: 10.1111/ejn.13443. Epub 2016 Nov 25.

PMID:
27748551
34.

Management of chronic visceral pain.

Olesen AE, Farmer AD, Olesen SS, Aziz Q, Drewes AM.

Pain Manag. 2016 Oct;6(5):469-86. doi: 10.2217/pmt-2015-0011. Epub 2016 Jun 3. Review.

PMID:
27256577
35.

A Model-Based Approach for Joint Analysis of Pain Intensity and Opioid Consumption in Postoperative Pain.

Juul RV, Knøsgaard KR, Olesen AE, Pedersen KV, Kreilgaard M, Christrup LL, Osther PJ, Drewes AM, Lund TM.

AAPS J. 2016 Jul;18(4):1013-22. doi: 10.1208/s12248-016-9921-2. Epub 2016 Apr 26.

PMID:
27116023
36.

Association between Gene Polymorphisms and Pain Sensitivity Assessed in a Multi-Modal Multi-Tissue Human Experimental Model - An Explorative Study.

Nielsen LM, Olesen AE, Sato H, Christrup LL, Drewes AM.

Basic Clin Pharmacol Toxicol. 2016 Oct;119(4):360-6. doi: 10.1111/bcpt.12601. Epub 2016 May 2.

37.

Acute Metabolic Changes Associated With Analgesic Drugs: An MR Spectroscopy Study.

Hansen TM, Olesen AE, Simonsen CW, Fischer IW, Lelic D, Drewes AM, Frøkjaer JB.

J Neuroimaging. 2016 Sep;26(5):545-51. doi: 10.1111/jon.12345. Epub 2016 Mar 30.

PMID:
27028269
38.

Modelling the PKPD of oxycodone in experimental pain - Impact of opioid receptor polymorphisms.

Olsen R, Foster DJ, Upton RN, Olesen AE, Ross JR, Droney J, Sato H, Drewes AM, Kreilgaard M.

Eur J Pharm Sci. 2016 Apr 30;86:41-9. doi: 10.1016/j.ejps.2016.02.021. Epub 2016 Mar 2.

PMID:
26946441
39.

Does catastrophic thinking enhance oesophageal pain sensitivity? An experimental investigation.

Martel MO, Olesen AE, Jørgensen D, Nielsen LM, Brock C, Edwards RR, Drewes AM.

Eur J Pain. 2016 Sep;20(8):1214-22. doi: 10.1002/ejp.845. Epub 2016 Feb 26.

PMID:
26919233
40.

Evolving paradigms in the treatment of opioid-induced bowel dysfunction.

Poulsen JL, Brock C, Olesen AE, Nilsson M, Drewes AM.

Therap Adv Gastroenterol. 2015 Nov;8(6):360-72. doi: 10.1177/1756283X15589526. Review.

41.

Stochastic Pharmacokinetic-Pharmacodynamic Analysis of the Effect of Transdermal Buprenorphine on Electroencephalogram and Analgesia.

Olesen AE, Olofsen E, Andresen T, Graversen C, Drewes AM, Dahan A.

Anesth Analg. 2015 Nov;121(5):1165-75. doi: 10.1213/ANE.0000000000000939.

PMID:
26372412
42.

Multivariate analysis of single-sweep evoked brain potentials for pharmaco-electroencephalography.

Graversen C, Olesen AE, Staahl C, Drewes AM, Farina D.

Neuropsychobiology. 2015;71(4):241-52. doi: 10.1159/000375310. Epub 2015 Aug 13.

PMID:
26278118
43.

Machine learning on encephalographic activity may predict opioid analgesia.

Gram M, Graversen C, Olesen AE, Drewes AM.

Eur J Pain. 2015 Nov;19(10):1552-61. doi: 10.1002/ejp.734. Epub 2015 Jun 11.

PMID:
26095578
44.

The genetic influences on oxycodone response characteristics in human experimental pain.

Olesen AE, Sato H, Nielsen LM, Staahl C, Droney J, Gretton S, Branford R, Drewes AM, Arendt-Nielsen L, Riley J, Ross J.

Fundam Clin Pharmacol. 2015 Aug;29(4):417-25. doi: 10.1111/fcp.12128. Epub 2015 Jun 22.

PMID:
26042474
45.

The Effect of Oral Morphine on Pain-Related Brain Activation - An Experimental Functional Magnetic Resonance Imaging Study.

Hansen TM, Olesen AE, Graversen C, Drewes AM, Frøkjaer JB.

Basic Clin Pharmacol Toxicol. 2015 Nov;117(5):316-22. doi: 10.1111/bcpt.12415. Epub 2015 May 29.

46.

A review of morphine and morphine-6-glucuronide's pharmacokinetic-pharmacodynamic relationships in experimental and clinical pain.

Sverrisdóttir E, Lund TM, Olesen AE, Drewes AM, Christrup LL, Kreilgaard M.

Eur J Pharm Sci. 2015 Jul 10;74:45-62. doi: 10.1016/j.ejps.2015.03.020. Epub 2015 Apr 7. Review.

PMID:
25861720
47.

The effects of morphine and methylnaltrexone on gastrointestinal pain in healthy male participants.

Brokjaer A, Olesen AE, Christrup LL, Dahan A, Drewes AM.

Neurogastroenterol Motil. 2015 May;27(5):693-704. doi: 10.1111/nmo.12545. Epub 2015 Mar 22.

PMID:
25810023
48.

Study protocol for a randomised, double-blinded, placebo-controlled, clinical trial of S-ketamine for pain treatment in patients with chronic pancreatitis (RESET trial).

Juel J, Olesen SS, Olesen AE, Poulsen JL, Dahan A, Wilder-Smith O, Madzak A, Frøkjær JB, Drewes AM.

BMJ Open. 2015 Mar 10;5(3):e007087. doi: 10.1136/bmjopen-2014-007087.

49.

Objective markers of the analgesic response to morphine in experimental pain research.

Brokjær A, Olesen AE, Kreilgaard M, Graversen C, Gram M, Christrup LL, Dahan A, Drewes AM.

J Pharmacol Toxicol Methods. 2015 May-Jun;73:7-14. doi: 10.1016/j.vascn.2015.01.005. Epub 2015 Feb 7.

PMID:
25659520
50.

Single-sweep spectral analysis of contact heat evoked potentials: a novel approach to identify altered cortical processing after morphine treatment.

Hansen TM, Graversen C, Frøkjaer JB, Olesen AE, Valeriani M, Drewes AM.

Br J Clin Pharmacol. 2015 Jun;79(6):926-36. doi: 10.1111/bcp.12579.

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