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Items: 1 to 50 of 60

1.

Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology.

Reichenstein I, Eitan C, Diaz-Garcia S, Haim G, Magen I, Siany A, Hoye ML, Rivkin N, Olender T, Toth B, Ravid R, Mandelbaum AD, Yanowski E, Liang J, Rymer JK, Levy R, Beck G, Ainbinder E, Farhan SMK, Lennox KA, Bode NM, Behlke MA, Möller T, Saxena S, Moreno CAM, Costaguta G, van Eijk KR, Phatnani H, Al-Chalabi A, Başak AN, van den Berg LH, Hardiman O, Landers JE, Mora JS, Morrison KE, Shaw PJ, Veldink JH, Pfaff SL, Yizhar O, Gross C, Brown RH Jr, Ravits JM, Harms MB, Miller TM, Hornstein E.

Sci Transl Med. 2019 Dec 18;11(523). pii: eaav5264. doi: 10.1126/scitranslmed.aav5264.

2.

Interplay of LIS1 and MeCP2: Interactions and Implications With the Neurodevelopmental Disorders Lissencephaly and Rett Syndrome.

Keidar L, Gerlitz G, Kshirsagar A, Tsoory M, Olender T, Wang X, Yang Y, Chen YS, Yang YG, Voineagu I, Reiner O.

Front Cell Neurosci. 2019 Aug 14;13:370. doi: 10.3389/fncel.2019.00370. eCollection 2019.

3.

A secretion-enhancing cis regulatory targeting element (SECReTE) involved in mRNA localization and protein synthesis.

Cohen-Zontag O, Baez C, Lim LQJ, Olender T, Schirman D, Dahary D, Pilpel Y, Gerst JE.

PLoS Genet. 2019 Jul 1;15(7):e1008248. doi: 10.1371/journal.pgen.1008248. eCollection 2019 Jul.

4.

Noncoding deletions reveal a gene that is critical for intestinal function.

Oz-Levi D, Olender T, Bar-Joseph I, Zhu Y, Marek-Yagel D, Barozzi I, Osterwalder M, Alkelai A, Ruzzo EK, Han Y, Vos ESM, Reznik-Wolf H, Hartman C, Shamir R, Weiss B, Shapiro R, Pode-Shakked B, Tatarskyy P, Milgrom R, Schvimer M, Barshack I, Imai DM, Coleman-Derr D, Dickel DE, Nord AS, Afzal V, van Bueren KL, Barnes RM, Black BL, Mayhew CN, Kuhar MF, Pitstick A, Tekman M, Stanescu HC, Wells JM, Kleta R, de Laat W, Goldstein DB, Pras E, Visel A, Lancet D, Anikster Y, Pennacchio LA.

Nature. 2019 Jul;571(7763):107-111. doi: 10.1038/s41586-019-1312-2. Epub 2019 Jun 19.

5.

An active β-lactamase is a part of an orchestrated cell wall stress resistance network of Bacillus subtilis and related rhizosphere species.

Bucher T, Keren-Paz A, Hausser J, Olender T, Cytryn E, Kolodkin-Gal I.

Environ Microbiol. 2019 Mar;21(3):1068-1085. doi: 10.1111/1462-2920.14526. Epub 2019 Feb 21.

PMID:
30637927
6.

A non-canonical role for the proneural gene Neurog1 as a negative regulator of neocortical neurogenesis.

Han S, Dennis DJ, Balakrishnan A, Dixit R, Britz O, Zinyk D, Touahri Y, Olender T, Brand M, Guillemot F, Kurrasch D, Schuurmans C.

Development. 2018 Oct 1;145(19). pii: dev157719. doi: 10.1242/dev.157719.

7.

The Disordered Landscape of the 20S Proteasome Substrates Reveals Tight Association with Phase Separated Granules.

Myers N, Olender T, Savidor A, Levin Y, Reuven N, Shaul Y.

Proteomics. 2018 Nov;18(21-22):e1800076. doi: 10.1002/pmic.201800076. Epub 2018 Aug 8.

PMID:
30039638
8.

Next-generation sequencing of patients with congenital anosmia.

Alkelai A, Olender T, Dode C, Shushan S, Tatarskyy P, Furman-Haran E, Boyko V, Gross-Isseroff R, Halvorsen M, Greenbaum L, Milgrom R, Yamada K, Haneishi A, Blau I, Lancet D.

Eur J Hum Genet. 2017 Dec;25(12):1377-1387. doi: 10.1038/s41431-017-0014-1. Epub 2017 Nov 13.

9.

Developmental activities of the complement pathway in migrating neurons.

Gorelik A, Sapir T, Haffner-Krausz R, Olender T, Woodruff TM, Reiner O.

Nat Commun. 2017 May 2;8:15096. doi: 10.1038/ncomms15096.

10.

Regulation of receptor-type protein tyrosine phosphatases by their C-terminal tail domains.

Barnea M, Olender T, Bedford MT, Elson A.

Biochem Soc Trans. 2016 Oct 15;44(5):1295-1303. Review.

PMID:
27911712
11.

Characterization of proteome dynamics during growth in oleate reveals a new peroxisome-targeting receptor.

Yifrach E, Chuartzman SG, Dahan N, Maskit S, Zada L, Weill U, Yofe I, Olender T, Schuldiner M, Zalckvar E.

J Cell Sci. 2016 Nov 1;129(21):4067-4075. Epub 2016 Sep 23.

12.

ORDB, HORDE, ODORactor and other on-line knowledge resources of olfactory receptor-odorant interactions.

Marenco L, Wang R, McDougal R, Olender T, Twik M, Bruford E, Liu X, Zhang J, Lancet D, Shepherd G, Crasto C.

Database (Oxford). 2016 Oct 2;2016. pii: baw132. Print 2016.

13.

The human olfactory transcriptome.

Olender T, Keydar I, Pinto JM, Tatarskyy P, Alkelai A, Chien MS, Fishilevich S, Restrepo D, Matsunami H, Gilad Y, Lancet D.

BMC Genomics. 2016 Aug 11;17(1):619. doi: 10.1186/s12864-016-2960-3.

14.

VarElect: the phenotype-based variation prioritizer of the GeneCards Suite.

Stelzer G, Plaschkes I, Oz-Levi D, Alkelai A, Olender T, Zimmerman S, Twik M, Belinky F, Fishilevich S, Nudel R, Guan-Golan Y, Warshawsky D, Dahary D, Kohn A, Mazor Y, Kaplan S, Iny Stein T, Baris HN, Rappaport N, Safran M, Lancet D.

BMC Genomics. 2016 Jun 23;17 Suppl 2:444. doi: 10.1186/s12864-016-2722-2.

15.

Identification of a Functional Risk Variant for Pemphigus Vulgaris in the ST18 Gene.

Vodo D, Sarig O, Geller S, Ben-Asher E, Olender T, Bochner R, Goldberg I, Nosgorodsky J, Alkelai A, Tatarskyy P, Peled A, Baum S, Barzilai A, Ibrahim SM, Zillikens D, Lancet D, Sprecher E.

PLoS Genet. 2016 May 5;12(5):e1006008. doi: 10.1371/journal.pgen.1006008. eCollection 2016 May.

16.

Genic insights from integrated human proteomics in GeneCards.

Fishilevich S, Zimmerman S, Kohn A, Iny Stein T, Olender T, Kolker E, Safran M, Lancet D.

Database (Oxford). 2016 Apr 5;2016. pii: baw030. doi: 10.1093/database/baw030. Print 2016.

17.

A role for TENM1 mutations in congenital general anosmia.

Alkelai A, Olender T, Haffner-Krausz R, Tsoory MM, Boyko V, Tatarskyy P, Gross-Isseroff R, Milgrom R, Shushan S, Blau I, Cohn E, Beeri R, Levy-Lahad E, Pras E, Lancet D.

Clin Genet. 2016 Sep;90(3):211-9. doi: 10.1111/cge.12782. Epub 2016 May 31.

PMID:
27040985
18.

Not so simple, not so subtle: the interspecies competition between Bacillus simplex and Bacillus subtilis and its impact on the evolution of biofilms.

Rosenberg G, Steinberg N, Oppenheimer-Shaanan Y, Olender T, Doron S, Ben-Ari J, Sirota-Madi A, Bloom-Ackermann Z, Kolodkin-Gal I.

NPJ Biofilms Microbiomes. 2016 Jan 27;2:15027. doi: 10.1038/npjbiofilms.2015.27. eCollection 2016.

19.

Exome sequencing as a differential diagnosis tool: resolving mild trichohepatoenteric syndrome.

Oz-Levi D, Weiss B, Lahad A, Greenberger S, Pode-Shakked B, Somech R, Olender T, Tatarsky P, Marek-Yagel D, Pras E, Anikster Y, Lancet D.

Clin Genet. 2015 Jun;87(6):602-3. doi: 10.1111/cge.12494. Epub 2014 Oct 21. No abstract available.

PMID:
25335910
20.

Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy.

Ruzzo EK, Capo-Chichi JM, Ben-Zeev B, Chitayat D, Mao H, Pappas AL, Hitomi Y, Lu YF, Yao X, Hamdan FF, Pelak K, Reznik-Wolf H, Bar-Joseph I, Oz-Levi D, Lev D, Lerman-Sagie T, Leshinsky-Silver E, Anikster Y, Ben-Asher E, Olender T, Colleaux L, Décarie JC, Blaser S, Banwell B, Joshi RB, He XP, Patry L, Silver RJ, Dobrzeniecka S, Islam MS, Hasnat A, Samuels ME, Aryal DK, Rodriguiz RM, Jiang YH, Wetsel WC, McNamara JO, Rouleau GA, Silver DL, Lancet D, Pras E, Mitchell GA, Michaud JL, Goldstein DB.

Neuron. 2013 Oct 16;80(2):429-41. doi: 10.1016/j.neuron.2013.08.013.

21.

HORDE: comprehensive resource for olfactory receptor genomics.

Olender T, Nativ N, Lancet D.

Methods Mol Biol. 2013;1003:23-38. doi: 10.1007/978-1-62703-377-0_2.

PMID:
23585031
22.

Mutation in TECPR2 reveals a role for autophagy in hereditary spastic paraparesis.

Oz-Levi D, Ben-Zeev B, Ruzzo EK, Hitomi Y, Gelman A, Pelak K, Anikster Y, Reznik-Wolf H, Bar-Joseph I, Olender T, Alkelai A, Weiss M, Ben-Asher E, Ge D, Shianna KV, Elazar Z, Goldstein DB, Pras E, Lancet D.

Am J Hum Genet. 2012 Dec 7;91(6):1065-72. doi: 10.1016/j.ajhg.2012.09.015. Epub 2012 Nov 21.

23.

General olfactory sensitivity database (GOSdb): candidate genes and their genomic variations.

Keydar I, Ben-Asher E, Feldmesser E, Nativ N, Oshimoto A, Restrepo D, Matsunami H, Chien MS, Pinto JM, Gilad Y, Olender T, Lancet D.

Hum Mutat. 2013 Jan;34(1):32-41. doi: 10.1002/humu.22212. Epub 2012 Oct 11.

24.

Personal receptor repertoires: olfaction as a model.

Olender T, Waszak SM, Viavant M, Khen M, Ben-Asher E, Reyes A, Nativ N, Wysocki CJ, Ge D, Lancet D.

BMC Genomics. 2012 Aug 21;13:414. doi: 10.1186/1471-2164-13-414.

25.

Evolutionary grass roots for odor recognition.

Olender T, Lancet D.

Chem Senses. 2012 Sep;37(7):581-4. doi: 10.1093/chemse/bjs054. Epub 2012 Jun 13.

PMID:
22695794
26.

Genome sequence of the pattern-forming social bacterium Paenibacillus dendritiformis C454 chiral morphotype.

Sirota-Madi A, Olender T, Helman Y, Brainis I, Finkelshtein A, Roth D, Hagai E, Leshkowitz D, Brodsky L, Galatenko V, Nikolaev V, Gutnick DL, Lancet D, Ben-Jacob E.

J Bacteriol. 2012 Apr;194(8):2127-8. doi: 10.1128/JB.00158-12.

27.

In-silico human genomics with GeneCards.

Stelzer G, Dalah I, Stein TI, Satanower Y, Rosen N, Nativ N, Oz-Levi D, Olender T, Belinky F, Bahir I, Krug H, Perco P, Mayer B, Kolker E, Safran M, Lancet D.

Hum Genomics. 2011 Oct;5(6):709-17.

28.

Genome sequence of the pattern forming Paenibacillus vortex bacterium reveals potential for thriving in complex environments.

Sirota-Madi A, Olender T, Helman Y, Ingham C, Brainis I, Roth D, Hagi E, Brodsky L, Leshkowitz D, Galatenko V, Nikolaev V, Mugasimangalam RC, Bransburg-Zabary S, Gutnick DL, Lancet D, Ben-Jacob E.

BMC Genomics. 2010 Dec 17;11:710. doi: 10.1186/1471-2164-11-710.

29.

Systematic inference of copy-number genotypes from personal genome sequencing data reveals extensive olfactory receptor gene content diversity.

Waszak SM, Hasin Y, Zichner T, Olender T, Keydar I, Khen M, Stütz AM, Schlattl A, Lancet D, Korbel JO.

PLoS Comput Biol. 2010 Nov 11;6(11):e1000988. doi: 10.1371/journal.pcbi.1000988.

30.

Synthetic lethal hubs associated with vincristine resistant neuroblastoma.

Fechete R, Barth S, Olender T, Munteanu A, Bernthaler A, Inger A, Perco P, Lukas A, Lancet D, Cinatl J Jr, Michaelis M, Mayer B.

Mol Biosyst. 2011 Jan;7(1):200-14. doi: 10.1039/c0mb00082e. Epub 2010 Oct 28.

PMID:
21031175
31.

GeneCards Version 3: the human gene integrator.

Safran M, Dalah I, Alexander J, Rosen N, Iny Stein T, Shmoish M, Nativ N, Bahir I, Doniger T, Krug H, Sirota-Madi A, Olender T, Golan Y, Stelzer G, Harel A, Lancet D.

Database (Oxford). 2010 Aug 5;2010:baq020. doi: 10.1093/database/baq020.

32.

The genome of a songbird.

Warren WC, Clayton DF, Ellegren H, Arnold AP, Hillier LW, Künstner A, Searle S, White S, Vilella AJ, Fairley S, Heger A, Kong L, Ponting CP, Jarvis ED, Mello CV, Minx P, Lovell P, Velho TA, Ferris M, Balakrishnan CN, Sinha S, Blatti C, London SE, Li Y, Lin YC, George J, Sweedler J, Southey B, Gunaratne P, Watson M, Nam K, Backström N, Smeds L, Nabholz B, Itoh Y, Whitney O, Pfenning AR, Howard J, Völker M, Skinner BM, Griffin DK, Ye L, McLaren WM, Flicek P, Quesada V, Velasco G, Lopez-Otin C, Puente XS, Olender T, Lancet D, Smit AF, Hubley R, Konkel MK, Walker JA, Batzer MA, Gu W, Pollock DD, Chen L, Cheng Z, Eichler EE, Stapley J, Slate J, Ekblom R, Birkhead T, Burke T, Burt D, Scharff C, Adam I, Richard H, Sultan M, Soldatov A, Lehrach H, Edwards SV, Yang SP, Li X, Graves T, Fulton L, Nelson J, Chinwalla A, Hou S, Mardis ER, Wilson RK.

Nature. 2010 Apr 1;464(7289):757-62. doi: 10.1038/nature08819.

33.

Single-nucleotide polymorphisms in the p53 pathway genes modify cancer risk in BRCA1 and BRCA2 carriers of Jewish-Ashkenazi descent.

Yarden RI, Friedman E, Metsuyanim S, Olender T, Ben-Asher E, Papa MZ.

Mol Carcinog. 2010 Jun;49(6):545-55. doi: 10.1002/mc.20618.

PMID:
20306497
34.

GeneDecks: paralog hunting and gene-set distillation with GeneCards annotation.

Stelzer G, Inger A, Olender T, Iny-Stein T, Dalah I, Harel A, Safran M, Lancet D.

OMICS. 2009 Dec;13(6):477-87. doi: 10.1089/omi.2009.0069.

PMID:
20001862
35.

Mutations and lethality in simulated prebiotic networks.

Inger A, Solomon A, Shenhav B, Olender T, Lancet D.

J Mol Evol. 2009 Nov;69(5):568-78. doi: 10.1007/s00239-009-9281-y. Epub 2009 Sep 29.

PMID:
19787385
36.

Common peptides shed light on evolution of Olfactory Receptors.

Gottlieb A, Olender T, Lancet D, Horn D.

BMC Evol Biol. 2009 May 5;9:91. doi: 10.1186/1471-2148-9-91.

37.

Human olfaction: from genomic variation to phenotypic diversity.

Hasin-Brumshtein Y, Lancet D, Olender T.

Trends Genet. 2009 Apr;25(4):178-84. doi: 10.1016/j.tig.2009.02.002. Epub 2009 Mar 18. Review.

PMID:
19303166
38.

Evidence for an interaction of schizophrenia susceptibility loci on chromosome 6q23.3 and 10q24.33-q26.13 in Arab Israeli families.

Alkelai A, Kohn Y, Olender T, Sarner-Kanyas K, Rigbi A, Hamdan A, Ben-Asher E, Lancet D, Lerer B.

Am J Med Genet B Neuropsychiatr Genet. 2009 Oct 5;150B(7):914-25. doi: 10.1002/ajmg.b.30918.

PMID:
19152384
39.

Update on the olfactory receptor (OR) gene superfamily.

Olender T, Lancet D, Nebert DW.

Hum Genomics. 2008 Sep;3(1):87-97. Review.

40.

High-resolution copy-number variation map reflects human olfactory receptor diversity and evolution.

Hasin Y, Olender T, Khen M, Gonzaga-Jauregui C, Kim PM, Urban AE, Snyder M, Gerstein MB, Lancet D, Korbel JO.

PLoS Genet. 2008 Nov;4(11):e1000249. doi: 10.1371/journal.pgen.1000249. Epub 2008 Nov 7.

41.

Genome analysis of the platypus reveals unique signatures of evolution.

Warren WC, Hillier LW, Marshall Graves JA, Birney E, Ponting CP, Grützner F, Belov K, Miller W, Clarke L, Chinwalla AT, Yang SP, Heger A, Locke DP, Miethke P, Waters PD, Veyrunes F, Fulton L, Fulton B, Graves T, Wallis J, Puente XS, López-Otín C, Ordóñez GR, Eichler EE, Chen L, Cheng Z, Deakin JE, Alsop A, Thompson K, Kirby P, Papenfuss AT, Wakefield MJ, Olender T, Lancet D, Huttley GA, Smit AF, Pask A, Temple-Smith P, Batzer MA, Walker JA, Konkel MK, Harris RS, Whittington CM, Wong ES, Gemmell NJ, Buschiazzo E, Vargas Jentzsch IM, Merkel A, Schmitz J, Zemann A, Churakov G, Kriegs JO, Brosius J, Murchison EP, Sachidanandam R, Smith C, Hannon GJ, Tsend-Ayush E, McMillan D, Attenborough R, Rens W, Ferguson-Smith M, Lefèvre CM, Sharp JA, Nicholas KR, Ray DA, Kube M, Reinhardt R, Pringle TH, Taylor J, Jones RC, Nixon B, Dacheux JL, Niwa H, Sekita Y, Huang X, Stark A, Kheradpour P, Kellis M, Flicek P, Chen Y, Webber C, Hardison R, Nelson J, Hallsworth-Pepin K, Delehaunty K, Markovic C, Minx P, Feng Y, Kremitzki C, Mitreva M, Glasscock J, Wylie T, Wohldmann P, Thiru P, Nhan MN, Pohl CS, Smith SM, Hou S, Nefedov M, de Jong PJ, Renfree MB, Mardis ER, Wilson RK.

Nature. 2008 May 8;453(7192):175-83. doi: 10.1038/nature06936. Erratum in: Nature. 2008 Sep 11;455(7210):256. Nefedov, Mikhail [added]; de Jong, Pieter J [added].

42.

MDM2 SNP309 accelerates breast and ovarian carcinogenesis in BRCA1 and BRCA2 carriers of Jewish-Ashkenazi descent.

Yarden RI, Friedman E, Metsuyanim S, Olender T, Ben-Asher E, Papa MZ.

Breast Cancer Res Treat. 2008 Oct;111(3):497-504. Epub 2007 Nov 18.

PMID:
18026875
43.

Association of the RGS2 gene with extrapyramidal symptoms induced by treatment with antipsychotic medication.

Greenbaum L, Strous RD, Kanyas K, Merbl Y, Horowitz A, Karni O, Katz E, Kotler M, Olender T, Deshpande SN, Lancet D, Ben-Asher E, Lerer B.

Pharmacogenet Genomics. 2007 Jul;17(7):519-28.

PMID:
17558307
44.

Ancient genomic architecture for mammalian olfactory receptor clusters.

Aloni R, Olender T, Lancet D.

Genome Biol. 2006;7(10):R88. Epub 2006 Oct 1.

45.

Association of the dopamine receptor interacting protein gene, NEF3, with early response to antipsychotic medication.

Strous RD, Greenbaum L, Kanyas K, Merbl Y, Horowitz A, Karni O, Viglin D, Olender T, Deshpande SN, Lancet D, Ben-Asher E, Lerer B.

Int J Neuropsychopharmacol. 2007 Jun;10(3):321-33. Epub 2006 May 31.

46.

Widespread ectopic expression of olfactory receptor genes.

Feldmesser E, Olender T, Khen M, Yanai I, Ophir R, Lancet D.

BMC Genomics. 2006 May 22;7:121.

47.

Why do young women smoke? I. Direct and interactive effects of environment, psychological characteristics and nicotinic cholinergic receptor genes.

Greenbaum L, Kanyas K, Karni O, Merbl Y, Olender T, Horowitz A, Yakir A, Lancet D, Ben-Asher E, Lerer B.

Mol Psychiatry. 2006 Mar;11(3):312-22, 223.

PMID:
16314871
48.

The CC2D1A, a member of a new gene family with C2 domains, is involved in autosomal recessive non-syndromic mental retardation.

Basel-Vanagaite L, Attia R, Yahav M, Ferland RJ, Anteki L, Walsh CA, Olender T, Straussberg R, Magal N, Taub E, Drasinover V, Alkelai A, Bercovich D, Rechavi G, Simon AJ, Shohat M.

J Med Genet. 2006 Mar;43(3):203-10. Epub 2005 Jul 20.

49.

The olfactory receptor universe--from whole genome analysis to structure and evolution.

Olender T, Feldmesser E, Atarot T, Eisenstein M, Lancet D.

Genet Mol Res. 2004 Dec 30;3(4):545-53.

50.

Genomic organisation of the UDP-N-acetylglucosamine-1-phosphotransferase gamma subunit (GNPTAG) and its mutations in mucolipidosis III.

Raas-Rothschild A, Bargal R, Goldman O, Ben-Asher E, Groener JE, Toutain A, Stemmer E, Ben-Neriah Z, Flusser H, Beemer FA, Penttinen M, Olender T, Rein AJ, Bach G, Zeigler M.

J Med Genet. 2004 Apr;41(4):e52. No abstract available.

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