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Items: 26

1.

Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.

Chakraborty AA, Laukka T, Myllykoski M, Ringel AE, Booker MA, Tolstorukov MY, Meng YJ, Meier SR, Jennings RB, Creech AL, Herbert ZT, McBrayer SK, Olenchock BA, Jaffe JD, Haigis MC, Beroukhim R, Signoretti S, Koivunen P, Kaelin WG Jr.

Science. 2019 Mar 15;363(6432):1217-1222. doi: 10.1126/science.aaw1026. Epub 2019 Mar 14.

PMID:
30872525
2.

Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma.

McBrayer SK, Mayers JR, DiNatale GJ, Shi DD, Khanal J, Chakraborty AA, Sarosiek KA, Briggs KJ, Robbins AK, Sewastianik T, Shareef SJ, Olenchock BA, Parker SJ, Tateishi K, Spinelli JB, Islam M, Haigis MC, Looper RE, Ligon KL, Bernstein BE, Carrasco RD, Cahill DP, Asara JM, Metallo CM, Yennawar NH, Vander Heiden MG, Kaelin WG Jr.

Cell. 2018 Sep 20;175(1):101-116.e25. doi: 10.1016/j.cell.2018.08.038. Epub 2018 Sep 13.

PMID:
30220459
3.

The circulating metabolome of human starvation.

Steinhauser ML, Olenchock BA, O'Keefe J, Lun M, Pierce KA, Lee H, Pantano L, Klibanski A, Shulman GI, Clish CB, Fazeli PK.

JCI Insight. 2018 Aug 23;3(16). pii: 121434. doi: 10.1172/jci.insight.121434. eCollection 2018 Aug 23.

4.

Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase.

McBrayer SK, Olenchock BA, DiNatale GJ, Shi DD, Khanal J, Jennings RB, Novak JS, Oser MG, Robbins AK, Modiste R, Bonal D, Moslehi J, Bronson RT, Neuberg D, Nguyen QD, Signoretti S, Losman JA, Kaelin WG Jr.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3741-E3748. doi: 10.1073/pnas.1716029115. Epub 2018 Apr 2.

5.

Prolyl Hydroxylase Domain-2 Inhibition Improves Skeletal Muscle Regeneration in a Male Murine Model of Obesity.

Sinha I, Sakthivel D, Olenchock BA, Kruse CR, Williams J, Varon DE, Smith JD, Madenci AL, Nuutila K, Wagers AJ.

Front Endocrinol (Lausanne). 2017 Jul 5;8:153. doi: 10.3389/fendo.2017.00153. eCollection 2017.

6.

Biochemical Underpinnings of Immune Cell Metabolic Phenotypes.

Olenchock BA, Rathmell JC, Vander Heiden MG.

Immunity. 2017 May 16;46(5):703-713. doi: 10.1016/j.immuni.2017.04.013. Review.

7.

Exploring effects of remote ischemic preconditioning in a pig model of hypothermic circulatory arrest.

Herajärvi J, Anttila T, Dimova EY, Laukka T, Myllymäki M, Haapanen H, Olenchock BA, Tuominen H, Puistola U, Karihtala P, Kiviluoma K, Koivunen P, Anttila V, Juvonen T.

Scand Cardiovasc J. 2017 Aug;51(4):233-241. doi: 10.1080/14017431.2017.1319574. Epub 2017 Apr 24.

PMID:
28434264
8.

Fulminant Myocarditis with Combination Immune Checkpoint Blockade.

Johnson DB, Balko JM, Compton ML, Chalkias S, Gorham J, Xu Y, Hicks M, Puzanov I, Alexander MR, Bloomer TL, Becker JR, Slosky DA, Phillips EJ, Pilkinton MA, Craig-Owens L, Kola N, Plautz G, Reshef DS, Deutsch JS, Deering RP, Olenchock BA, Lichtman AH, Roden DM, Seidman CE, Koralnik IJ, Seidman JG, Hoffman RD, Taube JM, Diaz LA Jr, Anders RA, Sosman JA, Moslehi JJ.

N Engl J Med. 2016 Nov 3;375(18):1749-1755.

9.

Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine.

Briggs KJ, Koivunen P, Cao S, Backus KM, Olenchock BA, Patel H, Zhang Q, Signoretti S, Gerfen GJ, Richardson AL, Witkiewicz AK, Cravatt BF, Clardy J, Kaelin WG Jr.

Cell. 2016 Jun 30;166(1):126-39. doi: 10.1016/j.cell.2016.05.042.

10.

EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection.

Olenchock BA, Moslehi J, Baik AH, Davidson SM, Williams J, Gibson WJ, Chakraborty AA, Pierce KA, Miller CM, Hanse EA, Kelekar A, Sullivan LB, Wagers AJ, Clish CB, Vander Heiden MG, Kaelin WG Jr.

Cell. 2016 Apr 7;165(2):497. doi: 10.1016/j.cell.2016.03.037. No abstract available.

11.

EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection.

Olenchock BA, Moslehi J, Baik AH, Davidson SM, Williams J, Gibson WJ, Chakraborty AA, Pierce KA, Miller CM, Hanse EA, Kelekar A, Sullivan LB, Wagers AJ, Clish CB, Vander Heiden MG, Kaelin WG Jr.

Cell. 2016 Feb 25;164(5):884-95. doi: 10.1016/j.cell.2016.02.006. Erratum in: Cell. 2016 Apr 7;165(2):497.

12.

Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.

Davidson SM, Papagiannakopoulos T, Olenchock BA, Heyman JE, Keibler MA, Luengo A, Bauer MR, Jha AK, O'Brien JP, Pierce KA, Gui DY, Sullivan LB, Wasylenko TM, Subbaraj L, Chin CR, Stephanopolous G, Mott BT, Jacks T, Clish CB, Vander Heiden MG.

Cell Metab. 2016 Mar 8;23(3):517-28. doi: 10.1016/j.cmet.2016.01.007. Epub 2016 Feb 4.

13.

Outcomes in patients undergoing percutaneous ventricular assist device implantation for cardiogenic shock.

Berg DD, Sukul D, O'Brien M, Scirica BM, Sobieszczyk PS, Olenchock BA, Bohula EA, Morrow DA.

Eur Heart J Acute Cardiovasc Care. 2016 Apr;5(2):108-16. doi: 10.1177/2048872615584079. Epub 2015 Apr 30.

14.

Providing initial transthoracic echocardiography training for anesthesiologists: simulator training is not inferior to live training.

Edrich T, Seethala RR, Olenchock BA, Mizuguchi AK, Rivero JM, Beutler SS, Fox JA, Liu X, Frendl G.

J Cardiothorac Vasc Anesth. 2014 Feb;28(1):49-53. doi: 10.1053/j.jvca.2013.07.011. Epub 2013 Oct 31.

PMID:
24183827
15.

Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells.

Fendt SM, Bell EL, Keibler MA, Olenchock BA, Mayers JR, Wasylenko TM, Vokes NI, Guarente L, Vander Heiden MG, Stephanopoulos G.

Nat Commun. 2013;4:2236. doi: 10.1038/ncomms3236.

16.

Pyruvate as a pivot point for oncogene-induced senescence.

Olenchock BA, Vander Heiden MG.

Cell. 2013 Jun 20;153(7):1429-30. doi: 10.1016/j.cell.2013.06.001.

17.

Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus.

Russo LA, Peano BJ, Trivedi SP, Cavalcanto TD, Olenchock BA, Caruso JA, Smolock AR, Vishnevsky O, Gardner RM.

Reprod Biol Endocrinol. 2009 Nov 4;7:124. doi: 10.1186/1477-7827-7-124.

18.

Current use of beta blockers in patients with reactive airway disease who are hospitalized with acute coronary syndromes.

Olenchock BA, Fonarow GG, Pan W, Hernandez A, Cannon CP; Get With The Guidelines Steering Committee.

Am J Cardiol. 2009 Feb 1;103(3):295-300. doi: 10.1016/j.amjcard.2008.09.081. Epub 2008 Nov 19.

PMID:
19166678
19.

The role of diacylglycerol kinases in T cell anergy.

Zhong XP, Olenchock BA, Koretzky GA.

Ernst Schering Found Symp Proc. 2007;(3):139-49. Review.

PMID:
18510102
20.

Lack of association between soluble CD40L and risk in a large cohort of patients with acute coronary syndrome in OPUS TIMI-16.

Olenchock BA, Wiviott SD, Murphy SA, Cannon CP, Rifai N, Braunwald E, Morrow DA.

J Thromb Thrombolysis. 2008 Oct;26(2):79-84. Epub 2007 Oct 5.

PMID:
17917707
21.

Disruption of diacylglycerol metabolism impairs the induction of T cell anergy.

Olenchock BA, Guo R, Carpenter JH, Jordan M, Topham MK, Koretzky GA, Zhong XP.

Nat Immunol. 2006 Nov;7(11):1174-81. Epub 2006 Oct 8.

PMID:
17028587
22.

Impaired degranulation but enhanced cytokine production after Fc epsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells.

Olenchock BA, Guo R, Silverman MA, Wu JN, Carpenter JH, Koretzky GA, Zhong XP.

J Exp Med. 2006 Jun 12;203(6):1471-80. Epub 2006 May 22.

23.
24.

Enhanced T cell responses due to diacylglycerol kinase zeta deficiency.

Zhong XP, Hainey EA, Olenchock BA, Jordan MS, Maltzman JS, Nichols KE, Shen H, Koretzky GA.

Nat Immunol. 2003 Sep;4(9):882-90. Epub 2003 Jul 27.

PMID:
12883552
25.

Regulation of hematopoietic cell development and activation by adapter proteins.

Koretzky GA, Abtahian F, Derimanov GS, Dmowski SA, Guerriero A, Jordan MS, Maltzman JS, Olenchock BA, Singer AL, Wu JN, Zhong XP.

Immunol Res. 2003;27(2-3):357-66. Review.

PMID:
12857981
26.

Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta.

Zhong XP, Hainey EA, Olenchock BA, Zhao H, Topham MK, Koretzky GA.

J Biol Chem. 2002 Aug 23;277(34):31089-98. Epub 2002 Jun 17.

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