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Items: 1 to 50 of 66

1.

Age dependent differences in the kinetics of γδ T cells after influenza vaccination.

Stervbo U, Pohlmann D, Baron U, Bozzetti C, Jürchott K, Mälzer JN, Nienen M, Olek S, Roch T, Schulz AR, Warth S, Neumann A, Thiel A, Grützkau A, Babel N.

PLoS One. 2017 Jul 11;12(7):e0181161. doi: 10.1371/journal.pone.0181161. eCollection 2017.

2.

Genetic Versus Epigenetic BRCA1 Silencing Pathways: Clinical Effects in Primary Ovarian Cancer Patients: A Study of the Tumor Bank Ovarian Cancer Consortium.

Sun T, Ruscito I, Dimitrova D, Chekerov R, Kulbe H, Baron U, Blanchard V, Panici PB, Darb-Esfahani S, Sehouli J, Olek S, Braicu EI.

Int J Gynecol Cancer. 2017 Oct;27(8):1658-1665. doi: 10.1097/IGC.0000000000001071.

PMID:
28691938
3.

The benzene metabolite 1,4-benzoquinone reduces regulatory T-cell function: A potential mechanism for tobacco smoke-associated atopic dermatitis.

Winter M, Thürmann L, Gu Z, Schüürmann G, Herberth G, Hinz D, von Bergen M, Harms H, Olek S, Röder S, Borte M, Eils R, Lehmann I, Trump S.

J Allergy Clin Immunol. 2017 Aug;140(2):603-605. doi: 10.1016/j.jaci.2017.01.034. Epub 2017 Mar 6. No abstract available.

4.

Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney-Bone Marrow Transplantation to Induce Transplantation Tolerance.

Sprangers B, DeWolf S, Savage TM, Morokata T, Obradovic A, LoCascio SA, Shonts B, Zuber J, Lau SP, Shah R, Morris H, Steshenko V, Zorn E, Preffer FI, Olek S, Dombkowski DM, Turka LA, Colvin R, Winchester R, Kawai T, Sykes M.

Am J Transplant. 2017 Aug;17(8):2020-2032. doi: 10.1111/ajt.14251. Epub 2017 Apr 10.

PMID:
28251801
5.

Prenatal phthalate exposure associates with low regulatory T-cell numbers and atopic dermatitis in early childhood: Results from the LINA mother-child study.

Herberth G, Pierzchalski A, Feltens R, Bauer M, Röder S, Olek S, Hinz D, Borte M, von Bergen M, Lehmann I; LINA Study Group.

J Allergy Clin Immunol. 2017 Apr;139(4):1376-1379.e8. doi: 10.1016/j.jaci.2016.09.034. Epub 2016 Nov 5. No abstract available.

6.

Clinical-grade regulatory T cells: Comparative analysis of large-scale expansion conditions.

Velaga S, Alter C, Dringenberg U, Thiesler CT, Kuhs S, Olek S, Ukena SN, Franzke A.

Exp Hematol. 2017 Jan;45:27-35.e1. doi: 10.1016/j.exphem.2016.09.008. Epub 2016 Sep 28.

PMID:
27693388
7.
8.

Erratum to: Effects of aging on human leukocytes (part II): immunophenotyping of adaptive immune B and T cell subsets.

Stervbo U, Bozzetti C, Baron U, Jürchott K, Meier S, Mälzer JN, Nienen M, Olek S, Rachwalik D, Schulz AR, Neumann A, Babel N, Grützkau A, Thiel A.

Age (Dordr). 2016 Dec;38(5-6):535-536. doi: 10.1007/s11357-016-9928-8. No abstract available.

9.

Imprinting of Skin/Inflammation Homing in CD4+ T Cells Is Controlled by DNA Methylation within the Fucosyltransferase 7 Gene.

Pink M, Ratsch BA, Mardahl M, Durek P, Polansky JK, Karl M, Baumgrass R, Wallner S, Cadenas C, Gianmoena K, Floess S, Chen W, Nordstroem K, Tierling S, Olek S, Walter J, Hamann A, Syrbe U.

J Immunol. 2016 Oct 15;197(8):3406-3414. Epub 2016 Sep 2.

10.

The Ratio of Regulatory (FOXP3+) to Total (CD3+) T Cells Determined by Epigenetic Cell Counting and Cardiovascular Disease Risk: A Prospective Case-cohort Study in Non-diabetics.

Barth SD, Kaaks R, Johnson T, Katzke V, Gellhaus K, Schulze JJ, Olek S, Kühn T.

EBioMedicine. 2016 Sep;11:151-156. doi: 10.1016/j.ebiom.2016.07.035. Epub 2016 Jul 30.

11.

Highly Predictive Model for a Protective Immune Response to the A(H1N1)pdm2009 Influenza Strain after Seasonal Vaccination.

Jürchott K, Schulz AR, Bozzetti C, Pohlmann D, Stervbo U, Warth S, Mälzer JN, Waldner J, Schweiger B, Olek S, Grützkau A, Babel N, Thiel A, Neumann AU.

PLoS One. 2016 Mar 8;11(3):e0150812. doi: 10.1371/journal.pone.0150812. eCollection 2016.

12.

The Zinc Concentration in the Diet and the Length of the Feeding Period Affect the Methylation Status of the ZIP4 Zinc Transporter Gene in Piglets.

Karweina D, Kreuzer-Redmer S, Müller U, Franken T, Pieper R, Baron U, Olek S, Zentek J, Brockmann GA.

PLoS One. 2015 Nov 23;10(11):e0143098. doi: 10.1371/journal.pone.0143098. eCollection 2015.

13.

Human in vitro induced T regulatory cells and memory T cells share common demethylation of specific FOXP3 promoter region.

Bégin P, Schulze J, Baron U, Olek S, Bauer RN, Passerini L, Baccheta R, Nadeau KC.

Clin Transl Allergy. 2015 Oct 20;5:35. doi: 10.1186/s13601-015-0079-2. eCollection 2015.

14.

Autologous stem cell transplantation aids autoimmune patients by functional renewal and TCR diversification of regulatory T cells.

Delemarre EM, van den Broek T, Mijnheer G, Meerding J, Wehrens EJ, Olek S, Boes M, van Herwijnen MJ, Broere F, van Royen A, Wulffraat NM, Prakken BJ, Spierings E, van Wijk F.

Blood. 2016 Jan 7;127(1):91-101. doi: 10.1182/blood-2015-06-649145. Epub 2015 Oct 19.

15.

Effects of aging on human leukocytes (part II): immunophenotyping of adaptive immune B and T cell subsets.

Stervbo U, Bozzetti C, Baron U, Jürchott K, Meier S, Mälzer JN, Nienen M, Olek S, Rachwalik D, Schulz AR, Neumann A, Babel N, Grützkau A, Thiel A.

Age (Dordr). 2015 Oct;37(5):93. doi: 10.1007/s11357-015-9829-2. Epub 2015 Sep 2. Erratum in: Age (Dordr). 2016 Oct 17;:.

16.

Effects of aging on human leukocytes (part I): immunophenotyping of innate immune cells.

Stervbo U, Meier S, Mälzer JN, Baron U, Bozzetti C, Jürchott K, Nienen M, Olek S, Rachwalik D, Schulz AR, Waldner JM, Neumann A, Babel N, Grützkau A, Thiel A.

Age (Dordr). 2015 Oct;37(5):92. doi: 10.1007/s11357-015-9828-3. Epub 2015 Sep 1.

17.

Treg-Mediated Immune Tolerance and the Risk of Solid Cancers: Findings From EPIC-Heidelberg.

Barth SD, Schulze JJ, Kühn T, Raschke E, Hüsing A, Johnson T, Kaaks R, Olek S.

J Natl Cancer Inst. 2015 Aug 22;107(11). pii: djv224. doi: 10.1093/jnci/djv224. Print 2015 Nov.

PMID:
26298011
18.

Foxp3(+) regulatory T cells are expanded in severe atopic dermatitis patients.

Roesner LM, Floess S, Witte T, Olek S, Huehn J, Werfel T.

Allergy. 2015 Dec;70(12):1656-60. doi: 10.1111/all.12712. Epub 2015 Aug 26.

PMID:
26228301
19.

Simultaneous statistical inference for epigenetic data.

Schildknecht K, Olek S, Dickhaus T.

PLoS One. 2015 May 12;10(5):e0125587. doi: 10.1371/journal.pone.0125587. eCollection 2015.

20.

Statins increase the frequency of circulating CD4+ FOXP3+ regulatory T cells in healthy individuals.

Rodríguez-Perea AL, Montoya CJ, Olek S, Chougnet CA, Velilla PA.

J Immunol Res. 2015;2015:762506. doi: 10.1155/2015/762506. Epub 2015 Feb 22.

21.

Regulatory T cells are not a strong predictor of survival for patients with glioblastoma.

Thomas AA, Fisher JL, Rahme GJ, Hampton TH, Baron U, Olek S, Schwachula T, Rhodes CH, Gui J, Tafe LJ, Tsongalis GJ, Lefferts JA, Wishart H, Kleen J, Miller M, Whipple CA, de Abreu FB, Ernstoff MS, Fadul CE.

Neuro Oncol. 2015 Jun;17(6):801-9. doi: 10.1093/neuonc/nou363. Epub 2015 Jan 24.

22.

Polymorphism of the IL-8 gene and the risk of ovarian cancer.

Koensgen D, Bruennert D, Ungureanu S, Sofroni D, Braicu EI, Sehouli J, Sümnig A, Delogu S, Zygmunt M, Goyal P, Evert M, Olek S, Biebler KE, Mustea A.

Cytokine. 2015 Feb;71(2):334-8. doi: 10.1016/j.cyto.2014.07.254. Epub 2014 Aug 21.

PMID:
25151495
23.

Th17/Treg ratio derived using DNA methylation analysis is associated with the late phase asthmatic response.

Singh A, Yamamoto M, Ruan J, Choi JY, Gauvreau GM, Olek S, Hoffmueller U, Carlsten C, FitzGerald JM, Boulet LP, O'Byrne PM, Tebbutt SJ.

Allergy Asthma Clin Immunol. 2014 Jun 24;10(1):32. doi: 10.1186/1710-1492-10-32. eCollection 2014.

24.

Isolation of human antigen-specific regulatory T cells with high suppressive function.

Noyan F, Lee YS, Zimmermann K, Hardtke-Wolenski M, Taubert R, Warnecke G, Knoefel AK, Schulde E, Olek S, Manns MP, Jaeckel E.

Eur J Immunol. 2014 Sep;44(9):2592-602. doi: 10.1002/eji.201344381. Epub 2014 Aug 8.

25.

Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors.

Peccatori J, Forcina A, Clerici D, Crocchiolo R, Vago L, Stanghellini MT, Noviello M, Messina C, Crotta A, Assanelli A, Marktel S, Olek S, Mastaglio S, Giglio F, Crucitti L, Lorusso A, Guggiari E, Lunghi F, Carrabba M, Tassara M, Battaglia M, Ferraro A, Carbone MR, Oliveira G, Roncarolo MG, Rossini S, Bernardi M, Corti C, Marcatti M, Patriarca F, Zecca M, Locatelli F, Bordignon C, Fleischhauer K, Bondanza A, Bonini C, Ciceri F.

Leukemia. 2015 Feb;29(2):396-405. doi: 10.1038/leu.2014.180. Epub 2014 Jun 4.

PMID:
24897508
26.

BRCA1 gene promoter methylation status in high-grade serous ovarian cancer patients--a study of the tumour Bank ovarian cancer (TOC) and ovarian cancer diagnosis consortium (OVCAD).

Ruscito I, Dimitrova D, Vasconcelos I, Gellhaus K, Schwachula T, Bellati F, Zeillinger R, Benedetti-Panici P, Vergote I, Mahner S, Cacsire-Tong D, Concin N, Darb-Esfahani S, Lambrechts S, Sehouli J, Olek S, Braicu EI.

Eur J Cancer. 2014 Aug;50(12):2090-8. doi: 10.1016/j.ejca.2014.05.001. Epub 2014 Jun 2.

PMID:
24889916
27.

Intrahepatic regulatory T cells in autoimmune hepatitis are associated with treatment response and depleted with current therapies.

Taubert R, Hardtke-Wolenski M, Noyan F, Wilms A, Baumann AK, Schlue J, Olek S, Falk CS, Manns MP, Jaeckel E.

J Hepatol. 2014 Nov;61(5):1106-14. doi: 10.1016/j.jhep.2014.05.034. Epub 2014 Jun 2.

PMID:
24882050
28.

Reduced FOXP3(+) regulatory T cells in patients with primary sclerosing cholangitis are associated with IL2RA gene polymorphisms.

Sebode M, Peiseler M, Franke B, Schwinge D, Schoknecht T, Wortmann F, Quaas A, Petersen BS, Ellinghaus E, Baron U, Olek S, Wiegard C, Weiler-Normann C, Lohse AW, Herkel J, Schramm C.

J Hepatol. 2014 May;60(5):1010-6. doi: 10.1016/j.jhep.2013.12.027. Epub 2014 Jan 8.

PMID:
24412607
29.

The cellular ratio of immune tolerance (immunoCRIT) is a definite marker for aggressiveness of solid tumors and may explain tumor dissemination patterns.

Türbachova I, Schwachula T, Vasconcelos I, Mustea A, Baldinger T, Jones KA, Bujard H, Olek A, Olek K, Gellhaus K, Braicu I, Könsgen D, Fryer C, Ravot E, Hellwag A, Westerfeld N, Gruss OJ, Meissner M, Hasan MT, Weber M, Hoffmüller U, Zimmermann S, Loddenkemper C, Mahner S, Babel N, Berns E, Adams R, Zeilinger R, Baron U, Vergote I, Maughan T, Marme F, Dickhaus T, Sehouli J, Olek S.

Epigenetics. 2013 Nov;8(11):1226-35. doi: 10.4161/epi.26334. Epub 2013 Sep 26.

PMID:
24071829
30.

Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and low regulatory T-cell numbers.

Herberth G, Bauer M, Gasch M, Hinz D, Röder S, Olek S, Kohajda T, Rolle-Kampczyk U, von Bergen M, Sack U, Borte M, Lehmann I; Lifestyle and Environmental Factors and Their Influence on Newborns Allergy Risk study group.

J Allergy Clin Immunol. 2014 Feb;133(2):543-50. doi: 10.1016/j.jaci.2013.06.036. Epub 2013 Aug 24.

PMID:
23978443
31.

Generation of highly effective and stable murine alloreactive Treg cells by combined anti-CD4 mAb, TGF-β, and RA treatment.

Schliesser U, Chopra M, Beilhack A, Appelt C, Vogel S, Schumann J, Panov I, Vogt K, Schlickeiser S, Olek S, Wood K, Brandt C, Volk HD, Sawitzki B.

Eur J Immunol. 2013 Dec;43(12):3291-305. doi: 10.1002/eji.201243292. Epub 2013 Sep 9.

32.

Low levels of naturally occurring regulatory T lymphocytes in blood of mares with early pregnancy loss.

Aurich C, Weber J, Nagel C, Merkl M, Jude R, Wostmann S, Ollech D, Baron U, Olek S, Jansen T.

Reprod Fertil Dev. 2014;26(6):827-33. doi: 10.1071/RD13012.

PMID:
23787006
33.

Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus.

Toker A, Engelbert D, Garg G, Polansky JK, Floess S, Miyao T, Baron U, Düber S, Geffers R, Giehr P, Schallenberg S, Kretschmer K, Olek S, Walter J, Weiss S, Hori S, Hamann A, Huehn J.

J Immunol. 2013 Apr 1;190(7):3180-8. doi: 10.4049/jimmunol.1203473. Epub 2013 Feb 18.

34.

Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity.

Goudy K, Aydin D, Barzaghi F, Gambineri E, Vignoli M, Ciullini Mannurita S, Doglioni C, Ponzoni M, Cicalese MP, Assanelli A, Tommasini A, Brigida I, Dellepiane RM, Martino S, Olek S, Aiuti A, Ciceri F, Roncarolo MG, Bacchetta R.

Clin Immunol. 2013 Mar;146(3):248-61. doi: 10.1016/j.clim.2013.01.004. Epub 2013 Jan 24.

35.

High immune response rates and decreased frequencies of regulatory T cells in metastatic renal cell carcinoma patients after tumor cell vaccination.

Pohla H, Buchner A, Stadlbauer B, Frankenberger B, Stevanovic S, Walter S, Frank R, Schwachula T, Olek S, Kopp J, Willimsky G, Stief CG, Hofstetter A, Pezzutto A, Blankenstein T, Oberneder R, Schendel DJ.

Mol Med. 2013 Feb 8;18:1499-508. doi: 10.2119/molmed.2012.00221.

36.

Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study.

Weisse K, Winkler S, Hirche F, Herberth G, Hinz D, Bauer M, Röder S, Rolle-Kampczyk U, von Bergen M, Olek S, Sack U, Richter T, Diez U, Borte M, Stangl GI, Lehmann I.

Allergy. 2013 Feb;68(2):220-8. doi: 10.1111/all.12081. Epub 2012 Dec 18.

PMID:
23253182
37.

Human regulatory T cells of G-CSF mobilized allogeneic stem cell donors qualify for clinical application.

Ukena SN, Velaga S, Goudeva L, Ivanyi P, Olek S, Falk CS, Ganser A, Franzke A.

PLoS One. 2012;7(12):e51644. doi: 10.1371/journal.pone.0051644. Epub 2012 Dec 12.

38.

Regulatory T-cells and associated pathways in metastatic renal cell carcinoma (mRCC) patients undergoing DC-vaccination and cytokine-therapy.

Schwarzer A, Wolf B, Fisher JL, Schwaab T, Olek S, Baron U, Tomlinson CR, Seigne JD, Crosby NA, Gui J, Hampton TH, Fadul CE, Heaney JA, Ernstoff MS.

PLoS One. 2012;7(10):e46600. doi: 10.1371/journal.pone.0046600. Epub 2012 Oct 31.

39.

An optimized multi-parameter flow cytometry protocol for human T regulatory cell analysis on fresh and viably frozen cells, correlation with epigenetic analysis, and comparison of cord and adult blood.

Nettenstrom L, Alderson K, Raschke EE, Evans MD, Sondel PM, Olek S, Seroogy CM.

J Immunol Methods. 2013 Jan 31;387(1-2):81-8. doi: 10.1016/j.jim.2012.09.014. Epub 2012 Oct 9.

40.

Enrichment of regulatory T cells in acutely rejected human liver allografts.

Taubert R, Pischke S, Schlue J, Wedemeyer H, Noyan F, Heim A, Lehner F, Barg-Hock H, Klempnauer J, Olek S, Manns MP, Hardtke-Wolenski M, Jaeckel E.

Am J Transplant. 2012 Dec;12(12):3425-36. doi: 10.1111/j.1600-6143.2012.04264.x. Epub 2012 Sep 20.

41.

FOXP3+ regulatory T cells in autoimmune hepatitis are fully functional and not reduced in frequency.

Peiseler M, Sebode M, Franke B, Wortmann F, Schwinge D, Quaas A, Baron U, Olek S, Wiegard C, Lohse AW, Weiler-Normann C, Schramm C, Herkel J.

J Hepatol. 2012 Jul;57(1):125-32. doi: 10.1016/j.jhep.2012.02.029. Epub 2012 Mar 14.

PMID:
22425700
42.

Demethylation analysis of the FOXP3 locus shows quantitative defects of regulatory T cells in IPEX-like syndrome.

Barzaghi F, Passerini L, Gambineri E, Ciullini Mannurita S, Cornu T, Kang ES, Choe YH, Cancrini C, Corrente S, Ciccocioppo R, Cecconi M, Zuin G, Discepolo V, Sartirana C, Schmidtko J, Ikinciogullari A, Ambrosi A, Roncarolo MG, Olek S, Bacchetta R.

J Autoimmun. 2012 Feb;38(1):49-58. doi: 10.1016/j.jaut.2011.12.009. Epub 2012 Jan 20.

43.

Induction of bona fide regulatory T cells after liver transplantation - the potential influence of polyclonal antithymocyte globulin.

Stauch D, Yahyazadeh A, Bova R, Melloh GC, Füldner A, Baron U, Olek S, Göldner K, Weiss S, Pratschke J, Kotsch K.

Transpl Int. 2012 Mar;25(3):302-13. doi: 10.1111/j.1432-2277.2011.01405.x. Epub 2011 Dec 21.

44.

Cord blood Tregs with stable FOXP3 expression are influenced by prenatal environment and associated with atopic dermatitis at the age of one year.

Hinz D, Bauer M, Röder S, Olek S, Huehn J, Sack U, Borte M, Simon JC, Lehmann I, Herberth G; LINA study group.

Allergy. 2012 Mar;67(3):380-9. doi: 10.1111/j.1398-9995.2011.02767.x. Epub 2011 Dec 22.

PMID:
22187950
45.

Forkhead box protein 3 (FOXP3) mutations lead to increased TH17 cell numbers and regulatory T-cell instability.

Passerini L, Olek S, Di Nunzio S, Barzaghi F, Hambleton S, Abinun M, Tommasini A, Vignola S, Cipolli M, Amendola M, Naldini L, Guidi L, Cecconi M, Roncarolo MG, Bacchetta R.

J Allergy Clin Immunol. 2011 Dec;128(6):1376-1379.e1. doi: 10.1016/j.jaci.2011.09.010. Epub 2011 Oct 13. No abstract available.

PMID:
22000569
46.

Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes.

Ferraro A, Socci C, Stabilini A, Valle A, Monti P, Piemonti L, Nano R, Olek S, Maffi P, Scavini M, Secchi A, Staudacher C, Bonifacio E, Battaglia M.

Diabetes. 2011 Nov;60(11):2903-13. doi: 10.2337/db11-0090. Epub 2011 Sep 6.

47.

Intragraft regulatory T cells in protocol biopsies retain foxp3 demethylation and are protective biomarkers for kidney graft outcome.

Bestard O, Cuñetti L, Cruzado JM, Lucia M, Valdez R, Olek S, Melilli E, Torras J, Mast R, Gomà M, Franquesa M, Grinyó JM.

Am J Transplant. 2011 Oct;11(10):2162-72. doi: 10.1111/j.1600-6143.2011.03633.x. Epub 2011 Jul 12.

48.

Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes.

McClymont SA, Putnam AL, Lee MR, Esensten JH, Liu W, Hulme MA, Hoffmüller U, Baron U, Olek S, Bluestone JA, Brusko TM.

J Immunol. 2011 Apr 1;186(7):3918-26. doi: 10.4049/jimmunol.1003099. Epub 2011 Mar 2.

49.

Epigenetic modification of the human CCR6 gene is associated with stable CCR6 expression in T cells.

Steinfelder S, Floess S, Engelbert D, Haeringer B, Baron U, Rivino L, Steckel B, Gruetzkau A, Olek S, Geginat J, Huehn J, Hamann A.

Blood. 2011 Mar 10;117(10):2839-46. doi: 10.1182/blood-2010-06-293027. Epub 2011 Jan 12.

50.

T regulatory cells in cord blood--FOXP3 demethylation as reliable quantitative marker.

Liu J, Lluis A, Illi S, Layland L, Olek S, von Mutius E, Schaub B.

PLoS One. 2010 Oct 12;5(10):e13267. doi: 10.1371/journal.pone.0013267.

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