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Items: 31


The moonlighting peroxiredoxin-glutaredoxin in Neisseria meningitidis binds plasminogen via a C-terminal lysine residue and contributes to survival in a whole blood model.

Aljannat MAK, Oldfield NJ, Albasri HM, Dorrington LKG, Ohri RL, Wooldridge KG, Turner DPJ.

Microb Pathog. 2019 Nov 23;139:103890. doi: 10.1016/j.micpath.2019.103890. [Epub ahead of print]


Potentiation of Phase Variation in Multiple Outer-Membrane Proteins During Spread of the Hyperinvasive Neisseria meningitidis Serogroup W ST-11 Lineage.

Green LR, Dave N, Adewoye AB, Lucidarme J, Clark SA, Oldfield NJ, Turner DPJ, Borrow R, Bayliss CD.

J Infect Dis. 2019 Aug 30;220(7):1109-1117. doi: 10.1093/infdis/jiz275.


Uptake of Neisserial autotransporter lipoprotein (NalP) promotes an increase in human brain microvascular endothelial cell metabolic activity.

Dufailu OA, Mahdavi J, Ala'Aldeen DAA, Wooldridge KG, Oldfield NJ.

Microb Pathog. 2018 Nov;124:70-75. doi: 10.1016/j.micpath.2018.08.001. Epub 2018 Aug 4.


Limited Impact of Adolescent Meningococcal ACWY Vaccination on Neisseria meningitidis Serogroup W Carriage in University Students.

Oldfield NJ, Green LR, Parkhill J, Bayliss CD, Turner DPJ.

J Infect Dis. 2018 Jan 30;217(4):608-616. doi: 10.1093/infdis/jix596.


Rise in Group W Meningococcal Carriage in University Students, United Kingdom.

Oldfield NJ, Cayrou C, AlJannat MAK, Al-Rubaiawi AAA, Green LR, Dada S, Steels OD, Stirrup C, Wanford J, Atwah BAY, Bayliss CD, Turner DPJ.

Emerg Infect Dis. 2017 Jun;23(6):1009-1011. doi: 10.3201/eid2306.161768.


University vaccine campaign increases meningococcal ACWY vaccine coverage.

Turner DP, Oldfield NJ, Bayliss CD.

Public Health. 2017 Apr;145:1-3. doi: 10.1016/j.puhe.2016.12.010. Epub 2017 Jan 12. No abstract available.


Genomic Analysis of Serogroup Y Neisseria meningitidis Isolates Reveals Extensive Similarities Between Carriage-Associated and Disease-Associated Organisms.

Oldfield NJ, Harrison OB, Bayliss CD, Maiden MC, Ala'Aldeen DA, Turner DP.

J Infect Dis. 2016 Jun 1;213(11):1777-85. doi: 10.1093/infdis/jiw008. Epub 2016 Jan 7.


Fructose-1,6-bisphosphate aldolase of Neisseria meningitidis binds human plasminogen via its C-terminal lysine residue.

Shams F, Oldfield NJ, Lai SK, Tunio SA, Wooldridge KG, Turner DP.

Microbiologyopen. 2016 Apr;5(2):340-50. doi: 10.1002/mbo3.331. Epub 2016 Jan 5.


Optimization of Molecular Approaches to Genogroup Neisseria meningitidis Carriage Isolates and Implications for Monitoring the Impact of New Serogroup B Vaccines.

Rojas E, Hoyos J, Oldfield NJ, Lee P, Flint M, Jones CH, Ala'Aldeen DA, Jansen KU, Anderson AS.

PLoS One. 2015 Jul 6;10(7):e0132140. doi: 10.1371/journal.pone.0132140. eCollection 2015.


Nuclear trafficking, histone cleavage and induction of apoptosis by the meningococcal App and MspA autotransporters.

Khairalla AS, Omer SA, Mahdavi J, Aslam A, Dufailu OA, Self T, Jonsson AB, Geörg M, Sjölinder H, Royer PJ, Martinez-Pomares L, Ghaemmaghami AM, Wooldridge KG, Oldfield NJ, Ala'Aldeen DA.

Cell Microbiol. 2015 Jul;17(7):1008-20. doi: 10.1111/cmi.12417. Epub 2015 Feb 8.


Fructose-1,6-bisphosphate aldolase (FBA)-a conserved glycolytic enzyme with virulence functions in bacteria: 'ill met by moonlight'.

Shams F, Oldfield NJ, Wooldridge KG, Turner DP.

Biochem Soc Trans. 2014 Dec;42(6):1792-5. doi: 10.1042/BST20140203. Review.


Deciphering the complex three-way interaction between the non-integrin laminin receptor, galectin-3 and Neisseria meningitidis.

Alqahtani F, Mahdavi J, Wheldon LM, Vassey M, Pirinccioglu N, Royer PJ, Qarani SM, Morroll S, Stoof J, Holliday ND, Teo SY, Oldfield NJ, Wooldridge KG, Ala'Aldeen DA.

Open Biol. 2014 Oct;4(10). pii: 140053. doi: 10.1098/rsob.140053.


Phase variation mediates reductions in expression of surface proteins during persistent meningococcal carriage.

Alamro M, Bidmos FA, Chan H, Oldfield NJ, Newton E, Bai X, Aidley J, Care R, Mattick C, Turner DP, Neal KR, Ala'aldeen DA, Feavers I, Borrow R, Bayliss CD.

Infect Immun. 2014 Jun;82(6):2472-84. doi: 10.1128/IAI.01521-14. Epub 2014 Mar 31.


A novel O-linked glycan modulates Campylobacter jejuni major outer membrane protein-mediated adhesion to human histo-blood group antigens and chicken colonization.

Mahdavi J, Pirinccioglu N, Oldfield NJ, Carlsohn E, Stoof J, Aslam A, Self T, Cawthraw SA, Petrovska L, Colborne N, Sihlbom C, Borén T, Wooldridge KG, Ala'Aldeen DA.

Open Biol. 2014 Jan 22;4:130202. doi: 10.1098/rsob.130202.


Prevalence and phase variable expression status of two autotransporters, NalP and MspA, in carriage and disease isolates of Neisseria meningitidis.

Oldfield NJ, Matar S, Bidmos FA, Alamro M, Neal KR, Turner DP, Bayliss CD, Ala'aldeen DA.

PLoS One. 2013 Jul 25;8(7):e69746. doi: 10.1371/journal.pone.0069746. Print 2013.


Mapping the laminin receptor binding domains of Neisseria meningitidis PorA and Haemophilus influenzae OmpP2.

Abouseada NM, Assafi MS, Mahdavi J, Oldfield NJ, Wheldon LM, Wooldridge KG, Ala'Aldeen DA.

PLoS One. 2012;7(9):e46233. doi: 10.1371/journal.pone.0046233. Epub 2012 Sep 25.


Cj1136 is required for lipooligosaccharide biosynthesis, hyperinvasion, and chick colonization by Campylobacter jejuni.

Javed MA, Cawthraw SA, Baig A, Li J, McNally A, Oldfield NJ, Newell DG, Manning G.

Infect Immun. 2012 Jul;80(7):2361-70. doi: 10.1128/IAI.00151-12. Epub 2012 Apr 16.


Carriage of meningococci by university students, United Kingdom.

Ala'aldeen DA, Oldfield NJ, Bidmos FA, Abouseada NM, Ahmed NW, Turner DP, Neal KR, Bayliss CD.

Emerg Infect Dis. 2011 Sep;17(9):1762-3. doi: 10.3201/eid1709.101762. No abstract available.


Persistence, replacement, and rapid clonal expansion of meningococcal carriage isolates in a 2008 university student cohort.

Bidmos FA, Neal KR, Oldfield NJ, Turner DP, Ala'Aldeen DA, Bayliss CD.

J Clin Microbiol. 2011 Feb;49(2):506-12. doi: 10.1128/JCM.01322-10. Epub 2010 Dec 1.


The role of glyceraldehyde 3-phosphate dehydrogenase (GapA-1) in Neisseria meningitidis adherence to human cells.

Tunio SA, Oldfield NJ, Ala'Aldeen DA, Wooldridge KG, Turner DP.

BMC Microbiol. 2010 Nov 9;10:280. doi: 10.1186/1471-2180-10-280.


Human antibody responses to the meningococcal factor H binding protein (LP2086) during invasive disease, colonization and carriage.

Ala'aldeen DA, Flint M, Oldfield NJ, Omer SA, McNeil LK, Jiang Q, Murphy E, Giardina PC, Novikova EG, Dodge-Scully IL, Bayliss CD, Turner DP, Neal KR, Hoiseth SK, Jansen KU, Anderson AS.

Vaccine. 2010 Nov 10;28(48):7667-75. doi: 10.1016/j.vaccine.2010.09.038. Epub 2010 Sep 25.


The moonlighting protein fructose-1, 6-bisphosphate aldolase of Neisseria meningitidis: surface localization and role in host cell adhesion.

Tunio SA, Oldfield NJ, Berry A, Ala'Aldeen DA, Wooldridge KG, Turner DP.

Mol Microbiol. 2010 May;76(3):605-15. doi: 10.1111/j.1365-2958.2010.07098.x. Epub 2010 Feb 28.


AasP autotransporter protein of Actinobacillus pleuropneumoniae does not protect pigs against homologous challenge.

Oldfield NJ, Worrall KE, Rycroft AN, Ali T, Wooldridge KG, Ala'Aldeen DA.

Vaccine. 2009 Aug 20;27(38):5278-83. doi: 10.1016/j.vaccine.2009.06.047. Epub 2009 Jun 27.


Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models.

Orihuela CJ, Mahdavi J, Thornton J, Mann B, Wooldridge KG, Abouseada N, Oldfield NJ, Self T, Ala'Aldeen DA, Tuomanen EI.

J Clin Invest. 2009 Jun;119(6):1638-46. doi: 10.1172/JCI36759. Epub 2009 May 11.


Functional characterization of AasP, a maturation protease autotransporter protein of Actinobacillus pleuropneumoniae.

Ali T, Oldfield NJ, Wooldridge KG, Turner DP, Ala'Aldeen DA.

Infect Immun. 2008 Dec;76(12):5608-14. doi: 10.1128/IAI.00085-08. Epub 2008 Oct 13.


Identification and characterization of novel antigenic vaccine candidates of Actinobacillus pleuropneumoniae.

Oldfield NJ, Donovan EA, Worrall KE, Wooldridge KG, Langford PR, Rycroft AN, Ala'Aldeen DA.

Vaccine. 2008 Apr 7;26(16):1942-54. doi: 10.1016/j.vaccine.2008.02.022. Epub 2008 Feb 27.


CapA, an autotransporter protein of Campylobacter jejuni, mediates association with human epithelial cells and colonization of the chicken gut.

Ashgar SS, Oldfield NJ, Wooldridge KG, Jones MA, Irving GJ, Turner DP, Ala'Aldeen DA.

J Bacteriol. 2007 Mar;189(5):1856-65. Epub 2006 Dec 15.


T-cell stimulating protein A (TspA) of Neisseria meningitidis is required for optimal adhesion to human cells.

Oldfield NJ, Bland SJ, Taraktsoglou M, Dos Ramos FJ, Robinson K, Wooldridge KG, Ala'Aldeen DA.

Cell Microbiol. 2007 Feb;9(2):463-78. Epub 2006 Sep 11.


Detection of F508del mutation in cystic fibrosis transmembrane conductance regulator gene mutation among Malays.

Zilfalil BA, Sarina S, Liza-Sharmini AT, Oldfield NJ, Stenhouse SA.

Singapore Med J. 2006 Feb;47(2):129-33.


Cloning, mutation and distribution of a putative lipopolysaccharide biosynthesis locus in Campylobacter jejuni.

Wood AC, Oldfield NJ, O'Dwyer CA, Ketley JM.

Microbiology. 1999 Feb;145 ( Pt 2):379-88.


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