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Rapid Aldosterone-Mediated Signaling in the DCT Increases Activity of the Thiazide-Sensitive NaCl Cotransporter.

Cheng L, Poulsen SB, Wu Q, Esteva-Font C, Olesen ETB, Peng L, Olde B, Leeb-Lundberg LMF, Pisitkun T, Rieg T, Dimke H, Fenton RA.

J Am Soc Nephrol. 2019 Aug;30(8):1454-1470. doi: 10.1681/ASN.2018101025. Epub 2019 Jun 28.


Detection of Needle Dislodgement Using Extracorporeal Pressure Signals: A Feasibility Study.

Holmer M, Olde B, Sandberg F, Sörnmo L.

ASAIO J. 2019 Jun 19. doi: 10.1097/MAT.0000000000001020. [Epub ahead of print]


Human G protein-coupled receptor 30 is N-glycosylated and N-terminal domain asparagine 44 is required for receptor structure and activity.

Gonzalez de Valdivia E, Sandén C, Kahn R, Olde B, Leeb-Lundberg LMF.

Biosci Rep. 2019 Feb 26;39(2). pii: BSR20182436. doi: 10.1042/BSR20182436. Print 2019 Feb 28.


Monitoring respiration using the pressure sensors in a dialysis machine.

Sandberg F, Holmer M, Olde B.

Physiol Meas. 2019 Feb 8;40(2):025001. doi: 10.1088/1361-6579/aaf978.


Effect of exercise on the plasma vesicular proteome: a methodological study comparing acoustic trapping and centrifugation.

Bryl-Górecka P, Sathanoori R, Al-Mashat M, Olde B, Jögi J, Evander M, Laurell T, Erlinge D.

Lab Chip. 2018 Oct 9;18(20):3101-3111. doi: 10.1039/c8lc00686e.


Detection of ventricular premature beats based on the pressure signals of a hemodialysis machine.

Holmer M, Martínez JP, Gil E, Sandberg F, Olde B, Sörnmo L.

Med Eng Phys. 2018 Jan;51:49-55. doi: 10.1016/j.medengphy.2017.11.004. Epub 2017 Dec 8.


G protein-coupled estrogen receptor 1 (GPER1)/GPR30 increases ERK1/2 activity through PDZ motif-dependent and -independent mechanisms.

Gonzalez de Valdivia E, Broselid S, Kahn R, Olde B, Leeb-Lundberg LMF.

J Biol Chem. 2017 Jun 16;292(24):9932-9943. doi: 10.1074/jbc.M116.765875. Epub 2017 Apr 27.


P2Y2 receptor modulates shear stress-induced cell alignment and actin stress fibers in human umbilical vein endothelial cells.

Sathanoori R, Bryl-Gorecka P, Müller CE, Erb L, Weisman GA, Olde B, Erlinge D.

Cell Mol Life Sci. 2017 Feb;74(4):731-746. doi: 10.1007/s00018-016-2365-0. Epub 2016 Sep 20.


Cardiac signal estimation based on the arterial and venous pressure signals of a hemodialysis machine.

Holmer M, Sandberg F, Solem K, Olde B, Sörnmo L.

Physiol Meas. 2016 Sep;37(9):1499-515. doi: 10.1088/0967-3334/37/9/1499. Epub 2016 Aug 11.


Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure.

Smith JG, Felix JF, Morrison AC, Kalogeropoulos A, Trompet S, Wilk JB, Gidlöf O, Wang X, Morley M, Mendelson M, Joehanes R, Ligthart S, Shan X, Bis JC, Wang YA, Sjögren M, Ngwa J, Brandimarto J, Stott DJ, Aguilar D, Rice KM, Sesso HD, Demissie S, Buckley BM, Taylor KD, Ford I, Yao C, Liu C; CHARGE-SCD consortium; EchoGen consortium; QT-IGC consortium; CHARGE-QRS consortium, Sotoodehnia N, van der Harst P, Stricker BH, Kritchevsky SB, Liu Y, Gaziano JM, Hofman A, Moravec CS, Uitterlinden AG, Kellis M, van Meurs JB, Margulies KB, Dehghan A, Levy D, Olde B, Psaty BM, Cupples LA, Jukema JW, Djousse L, Franco OH, Boerwinkle E, Boyer LA, Newton-Cheh C, Butler J, Vasan RS, Cappola TP, Smith NL.

PLoS Genet. 2016 May 5;12(5):e1006034. doi: 10.1371/journal.pgen.1006034. eCollection 2016 May.


G Protein-Coupled Estrogen Receptor 1 Mediates Acute Estrogen-Induced Cardioprotection via MEK/ERK/GSK-3β Pathway after Ischemia/Reperfusion.

Kabir ME, Singh H, Lu R, Olde B, Leeb-Lundberg LM, Bopassa JC.

PLoS One. 2015 Sep 10;10(9):e0135988. doi: 10.1371/journal.pone.0135988. eCollection 2015.


Myocardin Family Members Drive Formation of Caveolae.

Krawczyk KK, Yao Mattisson I, Ekman M, Oskolkov N, Grantinge R, Kotowska D, Olde B, Hansson O, Albinsson S, Miano JM, Rippe C, Swärd K.

PLoS One. 2015 Aug 5;10(8):e0133931. doi: 10.1371/journal.pone.0133931. eCollection 2015.


Correction: The ATP Receptors P2X7 and P2X4 Modulate High Glucose and Palmitate-Induced Inflammatory Responses in Endothelial Cells.

Sathanoori R, Swärd K, Olde B, Erlinge D.

PLoS One. 2015 Jul 17;10(7):e0133346. doi: 10.1371/journal.pone.0133346. eCollection 2015. No abstract available.


Extracellular Uridine Triphosphate and Adenosine Triphosphate Attenuate Endothelial Inflammation through miR-22-Mediated ICAM-1 Inhibition.

Gidlöf O, Sathanoori R, Magistri M, Faghihi MA, Wahlestedt C, Olde B, Erlinge D.

J Vasc Res. 2015;52(2):71-80. doi: 10.1159/000431367. Epub 2015 Jun 13.


Non-contact acoustic capture of microparticles from small plasma volumes.

Evander M, Gidlöf O, Olde B, Erlinge D, Laurell T.

Lab Chip. 2015 Jun 21;15(12):2588-96. doi: 10.1039/c5lc00290g.


The ATP Receptors P2X7 and P2X4 Modulate High Glucose and Palmitate-Induced Inflammatory Responses in Endothelial Cells.

Sathanoori R, Swärd K, Olde B, Erlinge D.

PLoS One. 2015 May 4;10(5):e0125111. doi: 10.1371/journal.pone.0125111. eCollection 2015. Erratum in: PLoS One. 2015;10(7):e0133346.


Shear stress modulates endothelial KLF2 through activation of P2X4.

Sathanoori R, Rosi F, Gu BJ, Wiley JS, Müller CE, Olde B, Erlinge D.

Purinergic Signal. 2015 Mar;11(1):139-53. doi: 10.1007/s11302-014-9442-3. Epub 2015 Jan 8.


Extracting a cardiac signal from the extracorporeal pressure sensors of a hemodialysis machine.

Holmer M, Sandberg F, Solem K, Grigonyte E, Olde B, Sörnmo L.

IEEE Trans Biomed Eng. 2015 May;62(5):1305-15. doi: 10.1109/TBME.2014.2385964. Epub 2014 Dec 24.


G protein-coupled receptor 30 (GPR30) forms a plasma membrane complex with membrane-associated guanylate kinases (MAGUKs) and protein kinase A-anchoring protein 5 (AKAP5) that constitutively inhibits cAMP production.

Broselid S, Berg KA, Chavera TA, Kahn R, Clarke WP, Olde B, Leeb-Lundberg LM.

J Biol Chem. 2014 Aug 8;289(32):22117-27. doi: 10.1074/jbc.M114.566893. Epub 2014 Jun 24.


The brain-enriched microRNA miR-124 in plasma predicts neurological outcome after cardiac arrest.

Gilje P, Gidlöf O, Rundgren M, Cronberg T, Al-Mashat M, Olde B, Friberg H, Erlinge D.

Crit Care. 2014 Mar 3;18(2):R40. doi: 10.1186/cc13753.


The enteric nervous system of P2Y13 receptor null mice is resistant against high-fat-diet- and palmitic-acid-induced neuronal loss.

Voss U, Turesson MF, Robaye B, Boeynaems JM, Olde B, Erlinge D, Ekblad E.

Purinergic Signal. 2014 Sep;10(3):455-64. doi: 10.1007/s11302-014-9408-5. Epub 2014 Feb 9.


Enteric neuropathy can be induced by high fat diet in vivo and palmitic acid exposure in vitro.

Voss U, Sand E, Olde B, Ekblad E.

PLoS One. 2013 Dec 3;8(12):e81413. doi: 10.1371/journal.pone.0081413. eCollection 2013.


The G protein-coupled estrogen receptor 1 (GPER1/GPR30) agonist G-1 regulates vascular smooth muscle cell Ca²⁺ handling.

Holm A, Hellstrand P, Olde B, Svensson D, Leeb-Lundberg LM, Nilsson BO.

J Vasc Res. 2013;50(5):421-9. doi: 10.1159/000354252. Epub 2013 Sep 25.


G protein-coupled estrogen receptor is apoptotic and correlates with increased distant disease-free survival of estrogen receptor-positive breast cancer patients.

Broselid S, Cheng B, Sjöström M, Lövgren K, Klug-De Santiago HL, Belting M, Jirström K, Malmström P, Olde B, Bendahl PO, Hartman L, Fernö M, Leeb-Lundberg LM.

Clin Cancer Res. 2013 Apr 1;19(7):1681-92. doi: 10.1158/1078-0432.CCR-12-2376.


Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression.

Gidlöf O, van der Brug M, Ohman J, Gilje P, Olde B, Wahlestedt C, Erlinge D.

Blood. 2013 May 9;121(19):3908-17, S1-26. doi: 10.1182/blood-2012-10-461798. Epub 2013 Mar 14.


Cocaine- and amphetamine-regulated transcript (CART) protects beta cells against glucotoxicity and increases cell proliferation.

Sathanoori R, Olde B, Erlinge D, Göransson O, Wierup N.

J Biol Chem. 2013 Feb 1;288(5):3208-18. doi: 10.1074/jbc.M112.437145. Epub 2012 Dec 16.


High glucose and free fatty acids induce beta cell apoptosis via autocrine effects of ADP acting on the P2Y(13) receptor.

Tan C, Voss U, Svensson S, Erlinge D, Olde B.

Purinergic Signal. 2013 Mar;9(1):67-79. doi: 10.1007/s11302-012-9331-6. Epub 2012 Sep 1.


Farnesyl pyrophosphate is an endogenous antagonist to ADP-stimulated P2Y₁₂ receptor-mediated platelet aggregation.

Högberg C, Gidlöf O, Deflorian F, Jacobson KA, Abdelrahman A, Müller CE, Olde B, Erlinge D.

Thromb Haemost. 2012 Jul;108(1):119-32. doi: 10.1160/TH11-10-0749. Epub 2012 May 25.


The G protein-coupled oestrogen receptor 1 agonist G-1 disrupts endothelial cell microtubule structure in a receptor-independent manner.

Holm A, Grände PO, Ludueña RF, Olde B, Prasad V, Leeb-Lundberg LM, Nilsson BO.

Mol Cell Biochem. 2012 Jul;366(1-2):239-49. doi: 10.1007/s11010-012-1301-3. Epub 2012 Mar 27.


Ticagrelor induces adenosine triphosphate release from human red blood cells.

Ohman J, Kudira R, Albinsson S, Olde B, Erlinge D.

Biochem Biophys Res Commun. 2012 Feb 24;418(4):754-8. doi: 10.1016/j.bbrc.2012.01.093. Epub 2012 Jan 27.


Plasma levels of liver-specific miR-122 is massively increased in a porcine cardiogenic shock model and attenuated by hypothermia.

Andersson P, Gidlöf O, Braun OO, Götberg M, van der Pals J, Olde B, Erlinge D.

Shock. 2012 Feb;37(2):234-8. doi: 10.1097/SHK.0b013e31823f1811.


17β-Estradiol induces nongenomic effects in renal intercalated cells through G protein-coupled estrogen receptor 1.

Hofmeister MV, Damkier HH, Christensen BM, Olde B, Fredrik Leeb-Lundberg LM, Fenton RA, Praetorius HA, Praetorius J.

Am J Physiol Renal Physiol. 2012 Feb 1;302(3):F358-68. doi: 10.1152/ajprenal.00343.2011. Epub 2011 Oct 12.


The GPER1 agonist G-1 attenuates endothelial cell proliferation by inhibiting DNA synthesis and accumulating cells in the S and G2 phases of the cell cycle.

Holm A, Baldetorp B, Olde B, Leeb-Lundberg LM, Nilsson BO.

J Vasc Res. 2011;48(4):327-35. doi: 10.1159/000322578. Epub 2011 Jan 27.


G protein-coupled oestrogen receptor 1 (GPER1)/GPR30: a new player in cardiovascular and metabolic oestrogenic signalling.

Nilsson BO, Olde B, Leeb-Lundberg LM.

Br J Pharmacol. 2011 Jul;163(6):1131-9. doi: 10.1111/j.1476-5381.2011.01235.x. Review.


G protein-coupled estrogen receptor 1/G protein-coupled receptor 30 localizes in the plasma membrane and traffics intracellularly on cytokeratin intermediate filaments.

Sandén C, Broselid S, Cornmark L, Andersson K, Daszkiewicz-Nilsson J, Mårtensson UE, Olde B, Leeb-Lundberg LM.

Mol Pharmacol. 2011 Mar;79(3):400-10. doi: 10.1124/mol.110.069500. Epub 2010 Dec 13.


Succinate independently stimulates full platelet activation via cAMP and phosphoinositide 3-kinase-β signaling.

Högberg C, Gidlöf O, Tan C, Svensson S, Nilsson-Öhman J, Erlinge D, Olde B.

J Thromb Haemost. 2011 Feb;9(2):361-72. doi: 10.1111/j.1538-7836.2010.04158.x.


Smokeless tobacco use among military flight personnel: a survey of 543 aviators.

McClellan SF, Olde BA, Freeman DH, Mann WF, Rotruck JR.

Aviat Space Environ Med. 2010 Jun;81(6):575-80.


ADP mediates inhibition of insulin secretion by activation of P2Y13 receptors in mice.

Amisten S, Meidute-Abaraviciene S, Tan C, Olde B, Lundquist I, Salehi A, Erlinge D.

Diabetologia. 2010 Sep;53(9):1927-34. doi: 10.1007/s00125-010-1807-8. Epub 2010 Jun 6.


Prediction of intradialytic hypotension using photoplethysmography.

Solem K, Olde B, Sörnmo L.

IEEE Trans Biomed Eng. 2010 Jul;57(7):1611-9. doi: 10.1109/TBME.2010.2042170. Epub 2010 Feb 18.


ADP receptor P2Y(13) induce apoptosis in pancreatic beta-cells.

Tan C, Salehi A, Svensson S, Olde B, Erlinge D.

Cell Mol Life Sci. 2010 Feb;67(3):445-53. doi: 10.1007/s00018-009-0191-3. Epub 2009 Nov 14.


GPR30/GPER1: searching for a role in estrogen physiology.

Olde B, Leeb-Lundberg LM.

Trends Endocrinol Metab. 2009 Oct;20(8):409-16. doi: 10.1016/j.tem.2009.04.006. Epub 2009 Sep 4. Review.


The role of the G protein-coupled receptor GPR30 in the effects of estrogen in ovariectomized mice.

Windahl SH, Andersson N, Chagin AS, Mårtensson UE, Carlsten H, Olde B, Swanson C, Movérare-Skrtic S, Sävendahl L, Lagerquist MK, Leeb-Lundberg LM, Ohlsson C.

Am J Physiol Endocrinol Metab. 2009 Mar;296(3):E490-6. doi: 10.1152/ajpendo.90691.2008. Epub 2008 Dec 16.


Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice.

Mårtensson UE, Salehi SA, Windahl S, Gomez MF, Swärd K, Daszkiewicz-Nilsson J, Wendt A, Andersson N, Hellstrand P, Grände PO, Owman C, Rosen CJ, Adamo ML, Lundquist I, Rorsman P, Nilsson BO, Ohlsson C, Olde B, Leeb-Lundberg LM.

Endocrinology. 2009 Feb;150(2):687-98. doi: 10.1210/en.2008-0623. Epub 2008 Oct 9.


Central venous oxygen saturation and thoracic admittance during dialysis: new approaches to hemodynamic monitoring.

Cordtz J, Olde B, Solem K, Ladefoged SD.

Hemodial Int. 2008 Jul;12(3):369-77. doi: 10.1111/j.1542-4758.2008.00283.x.


Palmitate-induced beta-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms.

Meidute Abaraviciene S, Lundquist I, Galvanovskis J, Flodgren E, Olde B, Salehi A.

PLoS One. 2008 May 14;3(5):e2182. doi: 10.1371/journal.pone.0002182. Erratum in: PLoS ONE. 2008;3(5). doi: 10.1371/annotation/21d1a1f6-35e9-4935-a8d0-387c057f1469. PLoS ONE. 2008;3(5). doi: 10.1371/annotation/682082fc-c500-414b-9f57-f9420c00c57e.


Hemodialysis blood access flow rates can be estimated accurately from on-line dialysate urea measurements and the knowledge of effective dialyzer urea clearance.

Lindsay RM, Sternby J, Olde B, Persson R, Thatcher ME, Sargent K.

Clin J Am Soc Nephrol. 2006 Sep;1(5):960-4. Epub 2006 Jul 6.


GPR40 is expressed in glucagon producing cells and affects glucagon secretion.

Flodgren E, Olde B, Meidute-Abaraviciene S, Winzell MS, Ahrén B, Salehi A.

Biochem Biophys Res Commun. 2007 Mar 2;354(1):240-5. Epub 2007 Jan 3.


Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastrointestinal lymphocytes.

Kotarsky K, Boketoft A, Bristulf J, Nilsson NE, Norberg A, Hansson S, Owman C, Sillard R, Leeb-Lundberg LM, Olde B.

J Pharmacol Exp Ther. 2006 Aug;318(2):619-28. Epub 2006 May 1.


Question asking and eye tracking during cognitive disequilibrium: comprehending illustrated texts on devices when the devices break down.

Graesser AC, Lu S, Olde BA, Cooper-Pye E, Whitten S.

Mem Cognit. 2005 Oct;33(7):1235-47.


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