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Items: 1 to 50 of 119

1.

Long non-coding RNA MANCR is a target of BET bromodomain protein BRD4 and plays a critical role in cellular migration and invasion abilities of prostate cancer.

Nagasawa M, Tomimatsu K, Terada K, Kondo K, Miyazaki K, Miyazaki M, Motooka D, Okuzaki D, Yoshida T, Kageyama S, Kawamoto H, Kawauchi A, Agata Y.

Biochem Biophys Res Commun. 2020 Mar 18. pii: S0006-291X(20)30522-2. doi: 10.1016/j.bbrc.2020.03.043. [Epub ahead of print]

PMID:
32199616
2.

In vivo dynamic analysis of BMP-2-induced ectopic bone formation.

Hashimoto K, Kaito T, Furuya M, Seno S, Okuzaki D, Kikuta J, Tsukazaki H, Matsuda H, Yoshikawa H, Ishii M.

Sci Rep. 2020 Mar 16;10(1):4751. doi: 10.1038/s41598-020-61825-2.

3.

DCLK1 integrates induction of TRIB3, EMT, drug resistance and poor prognosis in colorectal cancer.

Makino S, Takahashi H, Okuzaki D, Miyoshi N, Haraguchi N, Hata T, Matsuda C, Yamamoto H, Mizushima T, Mori M, Doki Y.

Carcinogenesis. 2020 Mar 10. pii: bgaa016. doi: 10.1093/carcin/bgaa016. [Epub ahead of print] No abstract available.

PMID:
32155234
4.

Error-free and error-prone DNA repair gene expression data through reprogramming and passage in human iPS cells.

Yoshimura Y, Okuzaki D.

Data Brief. 2020 Feb 6;29:105228. doi: 10.1016/j.dib.2020.105228. eCollection 2020 Apr.

5.

miR-4711-5p regulates cancer stemness and cell cycle progression via KLF5, MDM2 and TFDP1 in colon cancer cells.

Morimoto Y, Mizushima T, Wu X, Okuzaki D, Yokoyama Y, Inoue A, Hata T, Hirose H, Qian Y, Wang J, Miyoshi N, Takahashi H, Haraguchi N, Matsuda C, Doki Y, Mori M, Yamamoto H.

Br J Cancer. 2020 Feb 18. doi: 10.1038/s41416-020-0758-1. [Epub ahead of print]

PMID:
32066912
6.

Pathological and therapeutic implications of eosinophil-derived semaphorin 4D in eosinophilic chronic rhinosinusitis.

Tsuda T, Nishide M, Maeda Y, Hayama Y, Koyama S, Nojima S, Takamatsu H, Okuzaki D, Morita T, Nakatani T, Kato Y, Nakanishi Y, Futami Y, Suga Y, Naito Y, Konaka H, Satoh S, Naito M, Izumi M, Obata S, Nakatani A, Shikina T, Takeda K, Hayama M, Inohara H, Kumanogoh A.

J Allergy Clin Immunol. 2020 Mar;145(3):843-854.e4. doi: 10.1016/j.jaci.2019.12.893. Epub 2020 Feb 5.

7.

Rimonabant suppresses RNA transcription of hepatitis B virus by inhibiting hepatocyte nuclear factor 4α.

Sato A, Ono C, Tamura T, Mori H, Izumi T, Torii S, Fauzyah Y, Yamamoto T, Morioka Y, Okuzaki D, Fukuhara T, Matsuura Y.

Microbiol Immunol. 2020 Jan 25. doi: 10.1111/1348-0421.12777. [Epub ahead of print]

PMID:
31981244
8.

Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress.

Ichii M, Oritani K, Toda J, Saito H, Shi H, Shibayama H, Motooka D, Kitai Y, Muromoto R, Kashiwakura JI, Saitoh K, Okuzaki D, Matsuda T, Kanakura Y.

Haematologica. 2020 Jan 23. pii: haematol.2019.225573. doi: 10.3324/haematol.2019.225573. [Epub ahead of print]

9.

UNAGI: an automated pipeline for nanopore full-length cDNA sequencing uncovers novel transcripts and isoforms in yeast.

Al Kadi M, Jung N, Ito S, Kameoka S, Hishida T, Motooka D, Nakamura S, Iida T, Okuzaki D.

Funct Integr Genomics. 2020 Jan 18. doi: 10.1007/s10142-020-00732-1. [Epub ahead of print]

PMID:
31955296
10.

Analysis of genes linked to depressive-like behaviors in interleukin-18-deficient mice: Gene expression profiles in the brain.

Yamanishi K, Hashimoto T, Miyauchi M, Mukai K, Ikubo K, Uwa N, Watanabe Y, Ikawa T, Okuzaki D, Okamura H, Yamanishi H, Matsunaga H.

Biomed Rep. 2020 Jan;12(1):3-10. doi: 10.3892/br.2019.1259. Epub 2019 Nov 25.

11.

Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver.

Ueda T, Yokota T, Okuzaki D, Uno Y, Mashimo T, Kubota Y, Sudo T, Ishibashi T, Shingai Y, Doi Y, Ozawa T, Nakai R, Tanimura A, Ichii M, Ezoe S, Shibayama H, Oritani K, Kanakura Y.

Stem Cell Reports. 2019 Dec 10;13(6):992-1005. doi: 10.1016/j.stemcr.2019.11.002.

12.

c-Src promotes tumor progression through downregulation of microRNA-129-1-3p.

Okuzaki D, Yamauchi T, Mitani F, Miyata M, Ninomiya Y, Watanabe R, Akamatsu H, Oneyama C.

Cancer Sci. 2020 Feb;111(2):418-428. doi: 10.1111/cas.14269. Epub 2020 Jan 17.

13.

Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1.

Hasegawa T, Kikuta J, Sudo T, Matsuura Y, Matsui T, Simmons S, Ebina K, Hirao M, Okuzaki D, Yoshida Y, Hirao A, Kalinichenko VV, Yamaoka K, Takeuchi T, Ishii M.

Nat Immunol. 2019 Dec;20(12):1631-1643. doi: 10.1038/s41590-019-0526-7. Epub 2019 Nov 18.

PMID:
31740799
14.

Expression of polydom in dermal neurofibroma and surrounding dermis in von Recklinghausen's disease.

Kamitani T, Murota H, Arase N, Wataya-Kaneda M, Sato-Nishiuchi R, Sekiguchi K, Okuzaki D, Motooka D, Katayama I.

J Dermatol Sci. 2019 Nov;96(2):73-80. doi: 10.1016/j.jdermsci.2019.09.005. Epub 2019 Sep 16.

PMID:
31570272
15.

DCLK1 INTEGRATES INDUCTION OF TRIB3, EMT, DRUG RESISTANCE, and POOR PROGNOSIS IN COLORECTAL CANCER.

Makino S, Takahashi H, Okuzaki D, Miyoshi N, Haraguchi N, Hata T, Matsuda C, Yamamoto H, Mizushima T, Mori M, Doki Y.

Carcinogenesis. 2019 Sep 28. pii: bgz157. doi: 10.1093/carcin/bgz157. [Epub ahead of print]

PMID:
31562741
16.

Surface Pre-Reacted Glass Filler Contributes to Tertiary Dentin Formation through a Mechanism Different Than That of Hydraulic Calcium-Silicate Cement.

Okamoto M, Ali M, Komichi S, Watanabe M, Huang H, Ito Y, Miura J, Hirose Y, Mizuhira M, Takahashi Y, Okuzaki D, Kawabata S, Imazato S, Hayashi M.

J Clin Med. 2019 Sep 11;8(9). pii: E1440. doi: 10.3390/jcm8091440.

17.

E-cadherin-Fc chimera protein matrix enhances cancer stem-like properties and induces mesenchymal features in colon cancer cells.

Qian Y, Wu X, Yokoyama Y, Okuzaki D, Taguchi M, Hirose H, Wang J, Hata T, Inoue A, Hiraki M, Ohtsuka M, Takahashi H, Haraguchi N, Mizushima T, Tanaka S, Mori M, Yamamoto H.

Cancer Sci. 2019 Nov;110(11):3520-3532. doi: 10.1111/cas.14193. Epub 2019 Sep 30.

18.

DMPK is a New Candidate Mediator of Tumor Suppressor p53-Dependent Cell Death.

Itoh K, Ebata T, Hirata H, Torii T, Sugimoto W, Onodera K, Nakajima W, Uehara I, Okuzaki D, Yamauchi S, Budirahardja Y, Nishikata T, Tanaka N, Kawauchi K.

Molecules. 2019 Sep 1;24(17). pii: E3175. doi: 10.3390/molecules24173175.

19.

Streptococcus pyogenes Transcriptome Changes in the Inflammatory Environment of Necrotizing Fasciitis.

Hirose Y, Yamaguchi M, Okuzaki D, Motooka D, Hamamoto H, Hanada T, Sumitomo T, Nakata M, Kawabata S.

Appl Environ Microbiol. 2019 Oct 16;85(21). pii: e01428-19. doi: 10.1128/AEM.01428-19. Print 2019 Nov 1.

20.

Distinct methylation levels of mature microRNAs in gastrointestinal cancers.

Konno M, Koseki J, Asai A, Yamagata A, Shimamura T, Motooka D, Okuzaki D, Kawamoto K, Mizushima T, Eguchi H, Takiguchi S, Satoh T, Mimori K, Ochiya T, Doki Y, Ofusa K, Mori M, Ishii H.

Nat Commun. 2019 Aug 29;10(1):3888. doi: 10.1038/s41467-019-11826-1.

21.

Elimination of protein aggregates prevents premature senescence in human trisomy 21 fibroblasts.

Nawa N, Hirata K, Kawatani K, Nambara T, Omori S, Banno K, Kokubu C, Takeda J, Nishimura K, Ohtaka M, Nakanishi M, Okuzaki D, Taniguchi H, Arahori H, Wada K, Kitabatake Y, Ozono K.

PLoS One. 2019 Jul 29;14(7):e0219592. doi: 10.1371/journal.pone.0219592. eCollection 2019.

22.

Characterization of human pegivirus infection in liver transplantation recipients.

Izumi T, Sakata K, Okuzaki D, Inokuchi S, Tamura T, Motooka D, Nakamura S, Ono C, Shimokawa M, Matsuura Y, Mori M, Fukuhara T, Yoshizumi T.

J Med Virol. 2019 Dec;91(12):2093-2100. doi: 10.1002/jmv.25555. Epub 2019 Aug 4.

PMID:
31350911
23.

Osteoclasts Modulate Bone Erosion in Cholesteatoma via RANKL Signaling.

Imai R, Sato T, Iwamoto Y, Hanada Y, Terao M, Ohta Y, Osaki Y, Imai T, Morihana T, Okazaki S, Oshima K, Okuzaki D, Katayama I, Inohara H.

J Assoc Res Otolaryngol. 2019 Oct;20(5):449-459. doi: 10.1007/s10162-019-00727-1. Epub 2019 Jun 28.

PMID:
31254133
24.

Metabolic adaptation to glycolysis is a basic defense mechanism of macrophages for Mycobacterium tuberculosis infection.

Osada-Oka M, Goda N, Saiga H, Yamamoto M, Takeda K, Ozeki Y, Yamaguchi T, Soga T, Tateishi Y, Miura K, Okuzaki D, Kobayashi K, Matsumoto S.

Int Immunol. 2019 Nov 8;31(12):781-793. doi: 10.1093/intimm/dxz048.

25.

CXCR4 regulates Plasmodium development in mouse and human hepatocytes.

Bando H, Pradipta A, Iwanaga S, Okamoto T, Okuzaki D, Tanaka S, Vega-Rodríguez J, Lee Y, Ma JS, Sakaguchi N, Soga A, Fukumoto S, Sasai M, Matsuura Y, Yuda M, Jacobs-Lorena M, Yamamoto M.

J Exp Med. 2019 Aug 5;216(8):1733-1748. doi: 10.1084/jem.20182227. Epub 2019 Jun 12.

26.

Serum deprivation-response protein regulates aldehyde dehydrogenase 1 through integrin-linked kinase signaling in endometrioid carcinoma cells.

Tahara S, Nojima S, Ohshima K, Hori Y, Kurashige M, Wada N, Motoyama Y, Okuzaki D, Ikeda JI, Morii E.

Cancer Sci. 2019 May;110(5):1804-1813. doi: 10.1111/cas.14007. Epub 2019 Apr 11.

27.

A new approach to identifying hypertension-associated genes in the mesenteric artery of spontaneously hypertensive rats and stroke-prone spontaneously hypertensive rats.

Ikawa T, Watanabe Y, Okuzaki D, Goto N, Okamura N, Yamanishi K, Higashino T, Yamanishi H, Okamura H, Higashino H.

J Hypertens. 2019 Aug;37(8):1644-1656. doi: 10.1097/HJH.0000000000002083.

28.

Extremely strong infiltration of WT1-specific CTLs into mouse tumor by the combination vaccine with WT1-specific CTL and helper peptides.

Nakata J, Nakajima H, Hayashibara H, Imafuku K, Morimoto S, Fujiki F, Motooka D, Okuzaki D, Hasegawa K, Hosen N, Tsuboi A, Oka Y, Kumanogoh A, Oji Y, Sugiyama H.

Oncotarget. 2018 Nov 13;9(89):36029-36038. doi: 10.18632/oncotarget.26338. eCollection 2018 Nov 13.

29.

Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia.

Yamanishi K, Maeda S, Kuwahara-Otani S, Hashimoto T, Ikubo K, Mukai K, Nakasho K, Gamachi N, El-Darawish Y, Li W, Okuzaki D, Watanabe Y, Yamanishi H, Okamura H, Matsunaga H.

J Transl Med. 2018 Nov 19;16(1):314. doi: 10.1186/s12967-018-1684-3.

30.

Clinical implications of monitoring nivolumab immunokinetics in non-small cell lung cancer patients.

Osa A, Uenami T, Koyama S, Fujimoto K, Okuzaki D, Takimoto T, Hirata H, Yano Y, Yokota S, Kinehara Y, Naito Y, Otsuka T, Kanazu M, Kuroyama M, Hamaguchi M, Koba T, Futami Y, Ishijima M, Suga Y, Akazawa Y, Machiyama H, Iwahori K, Takamatsu H, Nagatomo I, Takeda Y, Kida H, Akbay EA, Hammerman PS, Wong KK, Dranoff G, Mori M, Kijima T, Kumanogoh A.

JCI Insight. 2018 Oct 4;3(19). pii: 59125. doi: 10.1172/jci.insight.59125.

31.

A Convolutional Neural Network Uses Microscopic Images to Differentiate between Mouse and Human Cell Lines and Their Radioresistant Clones.

Toratani M, Konno M, Asai A, Koseki J, Kawamoto K, Tamari K, Li Z, Sakai D, Kudo T, Satoh T, Sato K, Motooka D, Okuzaki D, Doki Y, Mori M, Ogawa K, Ishii H.

Cancer Res. 2018 Dec 1;78(23):6703-6707. doi: 10.1158/0008-5472.CAN-18-0653. Epub 2018 Sep 25.

32.

Eosinophil-derived neurotoxin enhances airway remodeling in eosinophilic chronic rhinosinusitis and correlates with disease severity.

Tsuda T, Maeda Y, Nishide M, Koyama S, Hayama Y, Nojima S, Takamatsu H, Okuzaki D, Kinehara Y, Kato Y, Nakatani T, Obata S, Akazawa H, Shikina T, Takeda K, Hayama M, Inohara H, Kumanogoh A.

Int Immunol. 2019 Feb 6;31(1):33-40. doi: 10.1093/intimm/dxy061.

33.

Bystander inhibition of humoral immune responses by Epstein-Barr virus LMP1.

Tsai CY, Sakakibara S, Yasui T, Minamitani T, Okuzaki D, Kikutani H.

Int Immunol. 2018 Nov 14;30(12):579-590. doi: 10.1093/intimm/dxy053.

PMID:
30137504
34.

The Supercarbonate Apatite-MicroRNA Complex Inhibits Dextran Sodium Sulfate-Induced Colitis.

Fukata T, Mizushima T, Nishimura J, Okuzaki D, Wu X, Hirose H, Yokoyama Y, Kubota Y, Nagata K, Tsujimura N, Inoue A, Miyoshi N, Haraguchi N, Takahashi H, Hata T, Matsuda C, Kayama H, Takeda K, Doki Y, Mori M, Yamamoto H.

Mol Ther Nucleic Acids. 2018 Sep 7;12:658-671. doi: 10.1016/j.omtn.2018.07.007. Epub 2018 Aug 6.

35.

Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles.

Kayama H, Kohyama M, Okuzaki D, Motooka D, Barman S, Okumura R, Muneta M, Hoshino K, Sasaki I, Ise W, Matsuno H, Nishimura J, Kurosaki T, Nakamura S, Arase H, Kaisho T, Takeda K.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8418-8423. doi: 10.1073/pnas.1808426115. Epub 2018 Jul 30.

36.

MicroRNA-137-mediated Src oncogenic signaling promotes cancer progression.

Kokuda R, Watanabe R, Okuzaki D, Akamatsu H, Oneyama C.

Genes Cells. 2018 Jul 2. doi: 10.1111/gtc.12610. [Epub ahead of print]

37.

Variable SATB1 Levels Regulate Hematopoietic Stem Cell Heterogeneity with Distinct Lineage Fate.

Doi Y, Yokota T, Satoh Y, Okuzaki D, Tokunaga M, Ishibashi T, Sudo T, Ueda T, Shingai Y, Ichii M, Tanimura A, Ezoe S, Shibayama H, Kohwi-Shigematsu T, Takeda J, Oritani K, Kanakura Y.

Cell Rep. 2018 Jun 12;23(11):3223-3235. doi: 10.1016/j.celrep.2018.05.042.

38.

Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization.

Kang S, Nakanishi Y, Kioi Y, Okuzaki D, Kimura T, Takamatsu H, Koyama S, Nojima S, Nishide M, Hayama Y, Kinehara Y, Kato Y, Nakatani T, Shimogori T, Takagi J, Toyofuku T, Kumanogoh A.

Nat Immunol. 2018 Jun;19(6):561-570. doi: 10.1038/s41590-018-0108-0. Epub 2018 May 18.

PMID:
29777213
39.

In vivo visualisation of different modes of action of biological DMARDs inhibiting osteoclastic bone resorption.

Matsuura Y, Kikuta J, Kishi Y, Hasegawa T, Okuzaki D, Hirano T, Minoshima M, Kikuchi K, Kumanogoh A, Ishii M.

Ann Rheum Dis. 2018 Aug;77(8):1219-1225. doi: 10.1136/annrheumdis-2017-212880. Epub 2018 Apr 28.

PMID:
29705743
40.

Late cornified envelope 1C (LCE1C), a transcriptional target of TAp63 phosphorylated at T46/T281, interacts with PRMT5.

Yabuta N, Ota C, Sasakura T, Naito Y, Okuzaki D, Fukushima K, Nojima H.

Sci Rep. 2018 Mar 20;8(1):4892. doi: 10.1038/s41598-018-23045-7.

41.

A miR-29b Byproduct Sequence Exhibits Potent Tumor-Suppressive Activities via Inhibition of NF-κB Signaling in KRAS-Mutant Colon Cancer Cells.

Inoue A, Mizushima T, Wu X, Okuzaki D, Kambara N, Ishikawa S, Wang J, Qian Y, Hirose H, Yokoyama Y, Ikeshima R, Hiraki M, Miyoshi N, Takahashi H, Haraguchi N, Hata T, Matsuda C, Doki Y, Mori M, Yamamoto H.

Mol Cancer Ther. 2018 May;17(5):977-987. doi: 10.1158/1535-7163.MCT-17-0850. Epub 2018 Mar 15.

42.

Physiological and molecular effects of interleukin-18 administration on the mouse kidney.

Yamanishi K, Mukai K, Hashimoto T, Ikubo K, Nakasho K, El-Darawish Y, Li W, Okuzaki D, Watanabe Y, Hayakawa T, Nojima H, Yamanishi H, Okamura H, Matsunaga H.

J Transl Med. 2018 Mar 7;16(1):51. doi: 10.1186/s12967-018-1426-6.

43.

Adenylosuccinate lyase enhances aggressiveness of endometrial cancer by increasing killer cell lectin-like receptor C3 expression by fumarate.

Park H, Ohshima K, Nojima S, Tahara S, Kurashige M, Hori Y, Okuzaki D, Wada N, Ikeda JI, Morii E.

Lab Invest. 2018 Apr;98(4):449-461. doi: 10.1038/s41374-017-0017-0. Epub 2018 Feb 21.

44.

Modest Static Pressure Suppresses Columnar Epithelial Cell Growth in Association with Cell Shape and Cytoskeletal Modifications.

Hagiyama M, Yabuta N, Okuzaki D, Inoue T, Takashima Y, Kimura R, Ri A, Ito A.

Front Physiol. 2017 Dec 5;8:997. doi: 10.3389/fphys.2017.00997. eCollection 2017.

45.

FCN1 (M-ficolin), which directly associates with immunoglobulin G1, is a molecular target of intravenous immunoglobulin therapy for Kawasaki disease.

Okuzaki D, Ota K, Takatsuki SI, Akiyoshi Y, Naoi K, Yabuta N, Saji T, Nojima H.

Sci Rep. 2017 Sep 12;7(1):11334. doi: 10.1038/s41598-017-11108-0.

46.

Lamtor1 Is Critically Required for CD4+ T Cell Proliferation and Regulatory T Cell Suppressive Function.

Hosokawa T, Kimura T, Nada S, Okuno T, Ito D, Kang S, Nojima S, Yamashita K, Nakatani T, Hayama Y, Kato Y, Kinehara Y, Nishide M, Mikami N, Koyama S, Takamatsu H, Okuzaki D, Ohkura N, Sakaguchi S, Okada M, Kumanogoh A.

J Immunol. 2017 Sep 15;199(6):2008-2019. doi: 10.4049/jimmunol.1700157. Epub 2017 Aug 2.

47.

Characterization of miR-122-independent propagation of HCV.

Ono C, Fukuhara T, Motooka D, Nakamura S, Okuzaki D, Yamamoto S, Tamura T, Mori H, Sato A, Uemura K, Fauzyah Y, Kurihara T, Suda T, Nishio A, Hmwe SS, Okamoto T, Tatsumi T, Takehara T, Chayama K, Wakita T, Koike K, Matsuura Y.

PLoS Pathog. 2017 May 11;13(5):e1006374. doi: 10.1371/journal.ppat.1006374. eCollection 2017 May.

48.

Argininosuccinate Synthase 1-Deficiency Enhances the Cell Sensitivity to Arginine through Decreased DEPTOR Expression in Endometrial Cancer.

Ohshima K, Nojima S, Tahara S, Kurashige M, Hori Y, Hagiwara K, Okuzaki D, Oki S, Wada N, Ikeda JI, Kanai Y, Morii E.

Sci Rep. 2017 Mar 30;7:45504. doi: 10.1038/srep45504.

49.

BATF2 inhibits immunopathological Th17 responses by suppressing Il23a expression during Trypanosoma cruzi infection.

Kitada S, Kayama H, Okuzaki D, Koga R, Kobayashi M, Arima Y, Kumanogoh A, Murakami M, Ikawa M, Takeda K.

J Exp Med. 2017 May 1;214(5):1313-1331. doi: 10.1084/jem.20161076. Epub 2017 Mar 29.

50.

Mouse model of Epstein-Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease.

Minamitani T, Ma Y, Zhou H, Kida H, Tsai CY, Obana M, Okuzaki D, Fujio Y, Kumanogoh A, Zhao B, Kikutani H, Kieff E, Gewurz BE, Yasui T.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):4751-4756. doi: 10.1073/pnas.1701836114. Epub 2017 Mar 28.

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