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Items: 1 to 50 of 939

1.

Integration Mapping of piggyBac-Mediated CD19 Chimeric Antigen Receptor T Cells Analyzed by Novel Tagmentation-Assisted PCR.

Hamada M, Nishio N, Okuno Y, Suzuki S, Kawashima N, Muramatsu H, Tsubota S, Wilson MH, Morita D, Kataoka S, Ichikawa D, Murakami N, Taniguchi R, Suzuki K, Kojima D, Sekiya Y, Nishikawa E, Narita A, Hama A, Kojima S, Nakazawa Y, Takahashi Y.

EBioMedicine. 2018 Aug 3. pii: S2352-3964(18)30251-2. doi: 10.1016/j.ebiom.2018.07.008. [Epub ahead of print]

2.

Biological and epidemiological evidence of anti-allergic effects of traditional Japanese food ume (Prunus mume).

Kono R, Nakamura M, Nomura S, Kitano N, Kagiya T, Okuno Y, Inada KI, Tokuda A, Utsunomiya H, Ueno M.

Sci Rep. 2018 Aug 3;8(1):11638. doi: 10.1038/s41598-018-30086-5.

3.

Impact of MR on mature adipocytes in high-fat/high-sucrose diet-induced obesity.

Hayakawa T, Minemura T, Onodera T, Shin J, Okuno Y, Fukuhara A, Otsuki M, Shimomura I.

J Endocrinol. 2018 Jul 26. pii: JOE-18-0026. doi: 10.1530/JOE-18-0026. [Epub ahead of print]

PMID:
30049823
4.

Cytokine production in whole-blood cultures following immunization with an influenza vaccine.

Nakayama T, Kumagai T, Kashiwagi Y, Yoshii H, Honjo K, Kubota-Koketsu R, Okuno Y, Suga S.

Hum Vaccin Immunother. 2018 Jul 23. doi: 10.1080/21645515.2018.1498435. [Epub ahead of print]

PMID:
30036123
5.

Identification of potential pathogenic viruses in patients with acute myocarditis using next-generation sequencing.

Takeuchi S, Kawada JI, Okuno Y, Horiba K, Suzuki T, Torii Y, Yasuda K, Numaguchi A, Kato T, Takahashi Y, Ito Y.

J Med Virol. 2018 Jul 16. doi: 10.1002/jmv.25263. [Epub ahead of print]

PMID:
30011073
6.

Kinetic Trapping of Folded Proteins Relative to Aggregates under Physiologically Relevant Conditions.

Varela AE, Lang JF, Wu Y, Dalphin MD, Stangl AJ, Okuno Y, Cavagnero S.

J Phys Chem B. 2018 Aug 9;122(31):7682-7698. doi: 10.1021/acs.jpcb.8b05360. Epub 2018 Jul 26.

PMID:
30001623
7.

Probing the nanoscale light emission properties of a CVD-grown MoS2 monolayer by tip-enhanced photoluminescence.

Okuno Y, Lancry O, Tempez A, Cairone C, Bosi M, Fabbri F, Chaigneau M.

Nanoscale. 2018 Aug 7;10(29):14055-14059. doi: 10.1039/c8nr02421a. Epub 2018 Jul 12.

PMID:
29999092
8.

Whole-exome analysis to detect congenital hemolytic anemia mimicking congenital dyserythropoietic anemia.

Hamada M, Doisaki S, Okuno Y, Muramatsu H, Hama A, Kawashima N, Narita A, Nishio N, Yoshida K, Kanno H, Manabe A, Taga T, Takahashi Y, Miyano S, Ogawa S, Kojima S.

Int J Hematol. 2018 Jun 23. doi: 10.1007/s12185-018-2482-7. [Epub ahead of print]

PMID:
29936674
9.

A patient with a GNAO1 mutation with decreased spontaneous movements, hypotonia, and dystonic features.

Okumura A, Maruyama K, Shibata M, Kurahashi H, Ishii A, Numoto S, Hirose S, Kawai T, Iso M, Kataoka S, Okuno Y, Muramatsu H, Kojima S.

Brain Dev. 2018 Jun 20. pii: S0387-7604(18)30266-3. doi: 10.1016/j.braindev.2018.06.005. [Epub ahead of print]

PMID:
29935962
10.

Metabolomic and microarray analyses of adipose tissue of dapagliflozin-treated mice, and effects of 3-hydroxybutyrate on induction of adiponectin in adipocytes.

Nishitani S, Fukuhara A, Shin J, Okuno Y, Otsuki M, Shimomura I.

Sci Rep. 2018 Jun 11;8(1):8805. doi: 10.1038/s41598-018-27181-y.

11.

Differential Roles of Rad18 and Chk2 in Genome Maintenance and Skin Carcinogenesis Following UV Exposure.

Tanoue Y, Toyoda T, Sun J, Mustofa MK, Tateishi C, Endo S, Motoyama N, Araki K, Wu D, Okuno Y, Tsukamoto T, Takeya M, Ihn H, Vaziri C, Tateishi S.

J Invest Dermatol. 2018 May 31. pii: S0022-202X(18)32036-0. doi: 10.1016/j.jid.2018.05.015. [Epub ahead of print]

PMID:
29859927
12.

Three Types of Broadly Reacting Antibodies against Influenza B Viruses Induced by Vaccination with Seasonal Influenza Viruses.

Hirano D, Ohshima N, Kubota-Koketsu R, Yamasaki A, Kurosawa G, Okuno Y, Yoshida S, Kurosawa Y.

J Immunol Res. 2018 May 8;2018:7251793. doi: 10.1155/2018/7251793. eCollection 2018.

13.

Sterol profiles are valuable biomarkers for phenotype expression of Conradi-Hünermann-Happle syndrome with EBP mutations.

Takeichi T, Honda A, Okuno Y, Kojima D, Kono M, Nakamura Y, Tohyama M, Tanaka T, Aoyama Y, Akiyama M.

Br J Dermatol. 2018 May 31. doi: 10.1111/bjd.16823. [Epub ahead of print] No abstract available.

PMID:
29851033
14.

Association between homologous recombination repair gene mutations and response to oxaliplatin in pancreatic cancer.

Kondo T, Kanai M, Kou T, Sakuma T, Mochizuki H, Kamada M, Nakatsui M, Uza N, Kodama Y, Masui T, Takaori K, Matsumoto S, Miyake H, Okuno Y, Muto M.

Oncotarget. 2018 Apr 13;9(28):19817-19825. doi: 10.18632/oncotarget.24865. eCollection 2018 Apr 13.

15.

Early intervention using high-precision radiotherapy preserved visual function for five consecutive patients with optic nerve sheath meningioma.

Inoue T, Mimura O, Masai N, Ohashi A, Ikenaga K, Okuno Y, Nishiguchi I, Oh R.

Int J Clin Oncol. 2018 Apr 30. doi: 10.1007/s10147-018-1284-5. [Epub ahead of print]

PMID:
29713911
16.

Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells.

Morita D, Nishio N, Saito S, Tanaka M, Kawashima N, Okuno Y, Suzuki S, Matsuda K, Maeda Y, Wilson MH, Dotti G, Rooney CM, Takahashi Y, Nakazawa Y.

Mol Ther Methods Clin Dev. 2017 Dec 22;8:131-140. doi: 10.1016/j.omtm.2017.12.003. eCollection 2018 Mar 16.

17.

Dysregulation of Epstein-Barr Virus Infection in Hypomorphic ZAP70 Mutation.

Hoshino A, Takashima T, Yoshida K, Morimoto A, Kawahara Y, Yeh TW, Okano T, Yamashita M, Mitsuiki N, Imai K, Sakatani T, Nakazawa A, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Kojima S, Morio T, Kanegane H.

J Infect Dis. 2018 Jul 24;218(5):825-834. doi: 10.1093/infdis/jiy231.

PMID:
29684201
18.

[Artificial Intelligence in Drug Discovery].

Fujiwara T, Kamada M, Okuno Y.

Gan To Kagaku Ryoho. 2018 Apr;45(4):593-596. Japanese.

PMID:
29650810
19.

Oxidative Stress Inhibits Healthy Adipose Expansion Through Suppression of SREBF1-Mediated Lipogenic Pathway.

Okuno Y, Fukuhara A, Hashimoto E, Kobayashi H, Kobayashi S, Otsuki M, Shimomura I.

Diabetes. 2018 Jun;67(6):1113-1127. doi: 10.2337/db17-1032. Epub 2018 Apr 4.

PMID:
29618580
20.

Bufalin induces DNA damage response under hypoxic condition in myeloma cells.

Fujii E, Inada Y, Kakoki M, Nishimura N, Endo S, Fujiwara S, Wada N, Kawano Y, Okuno Y, Sugimoto T, Hata H.

Oncol Lett. 2018 May;15(5):6443-6449. doi: 10.3892/ol.2018.8091. Epub 2018 Feb 21.

21.

[A nationwide multi-center questionnaire survey on the management and treatment of post-stroke seizure and epilepsy in Japan].

Higashida K, Tanaka T, Yamagami H, Tomari S, Fukuma K, Okuno Y, Abe S, Nagatsuka K, Toyoda K, Ihara M.

Rinsho Shinkeigaku. 2018 Apr 25;58(4):217-222. doi: 10.5692/clinicalneurol.cn-001126. Epub 2018 Mar 31. Japanese.

PMID:
29607916
22.

Novel inhibitor candidates of TRPV2 prevent damage of dystrophic myocytes and ameliorate against dilated cardiomyopathy in a hamster model.

Iwata Y, Katayama Y, Okuno Y, Wakabayashi S.

Oncotarget. 2018 Feb 8;9(18):14042-14057. doi: 10.18632/oncotarget.24449. eCollection 2018 Mar 6.

23.

Oxygen cost of thoracic and diaphragmatic breathing during hyperventilation in healthy males.

Ishii N, Tomita K, Suetake S, Okuno Y, Kawamura K, Takeshima R, Ohse H, Imura S.

J Phys Ther Sci. 2018 Feb;30(2):238-241. doi: 10.1589/jpts.30.238. Epub 2018 Feb 20.

24.

Li deposition and desolvation with electron transfer at a silicon/propylene-carbonate interface: transition-state and free-energy profiles by large-scale first-principles molecular dynamics.

Ohwaki T, Ozaki T, Okuno Y, Ikeshoji T, Imai H, Otani M.

Phys Chem Chem Phys. 2018 May 3;20(17):11586-11591. doi: 10.1039/c7cp08569a.

PMID:
29537050
25.

Comprehensive detection of pathogens in immunocompromised children with bloodstream infections by next-generation sequencing.

Horiba K, Kawada JI, Okuno Y, Tetsuka N, Suzuki T, Ando S, Kamiya Y, Torii Y, Yagi T, Takahashi Y, Ito Y.

Sci Rep. 2018 Feb 28;8(1):3784. doi: 10.1038/s41598-018-22133-y.

26.

An infant with generalized pustular psoriasis and geographic tongue had a heterozygous IL36RN mutation and IgG2 deficiency.

Oi R, Takeichi T, Okuno Y, Kojima D, Sugawara K, Kono M, Muramatsu H, Akiyama M.

J Dermatol Sci. 2018 May;90(2):216-218. doi: 10.1016/j.jdermsci.2018.01.017. Epub 2018 Feb 6. No abstract available.

PMID:
29454537
27.

Integrated molecular profiling of juvenile myelomonocytic leukemia.

Murakami N, Okuno Y, Yoshida K, Shiraishi Y, Nagae G, Suzuki K, Narita A, Sakaguchi H, Kawashima N, Wang X, Xu Y, Chiba K, Tanaka H, Hama A, Sanada M, Ito M, Hirayama M, Watanabe A, Ueno T, Kojima S, Aburatani H, Mano H, Miyano S, Ogawa S, Takahashi Y, Muramatsu H.

Blood. 2018 Apr 5;131(14):1576-1586. doi: 10.1182/blood-2017-07-798157. Epub 2018 Feb 2.

PMID:
29437595
28.

A secondary RET mutation in the activation loop conferring resistance to vandetanib.

Nakaoku T, Kohno T, Araki M, Niho S, Chauhan R, Knowles PP, Tsuchihara K, Matsumoto S, Shimada Y, Mimaki S, Ishii G, Ichikawa H, Nagatoishi S, Tsumoto K, Okuno Y, Yoh K, McDonald NQ, Goto K.

Nat Commun. 2018 Feb 12;9(1):625. doi: 10.1038/s41467-018-02994-7.

29.

Rapid recovery of vision following early intervention with fractionated stereotactic radiotherapy for optic nerve sheath meningioma.

Inoue T, Okuno Y, Nishiguchi I, Ikenaga K, Mimura O.

Int Med Case Rep J. 2018 Jan 30;11:17-22. doi: 10.2147/IMCRJ.S149592. eCollection 2018.

30.

Signs of atopic dermatitis and contact dermatitis affected by distinct H2-haplotype in the NC/Nga genetic background.

Ohkusu-Tsukada K, Ito D, Okuno Y, Tsukada T, Takahashi K.

Sci Rep. 2018 Feb 7;8(1):2586. doi: 10.1038/s41598-018-21049-x.

31.

Mild case of Hailey-Hailey disease caused by a novel ATP2C1 mutation.

Hanamura T, Takeichi T, Okuno Y, Ichikawa D, Kono M, Akiyama M.

J Dermatol. 2018 Jul;45(7):e207-e208. doi: 10.1111/1346-8138.14241. Epub 2018 Jan 31. No abstract available.

PMID:
29383827
32.

Core Binding Site of a Thioflavin-T-Derived Imaging Probe on Amyloid β Fibrils Predicted by Computational Methods.

Kawai R, Araki M, Yoshimura M, Kamiya N, Ono M, Saji H, Okuno Y.

ACS Chem Neurosci. 2018 May 16;9(5):957-966. doi: 10.1021/acschemneuro.7b00389. Epub 2018 Jan 30.

PMID:
29381047
33.

Biotransformation of (+)-isofraxinellone by Aspergillus niger and insect antifeedant activity.

Okuno Y, Marumoto S, Tsurumi J, Miyazawa M.

Nat Prod Res. 2018 Jan 24:1-4. doi: 10.1080/14786419.2017.1422180. [Epub ahead of print]

PMID:
29363347
34.

Impact of dexamethasone concentration on cartilage tissue formation from human synovial derived stem cells in vitro.

Chijimatsu R, Kobayashi M, Ebina K, Iwahashi T, Okuno Y, Hirao M, Fukuhara A, Nakamura N, Yoshikawa H.

Cytotechnology. 2018 Apr;70(2):819-829. doi: 10.1007/s10616-018-0191-y. Epub 2018 Jan 19.

PMID:
29352392
35.

Effect of heavy atoms on photochemically induced dynamic nuclear polarization in liquids.

Okuno Y, Cavagnero S.

J Magn Reson. 2018 Jan;286:172-187. doi: 10.1016/j.jmr.2017.12.001. Epub 2017 Dec 5.

PMID:
29274568
36.

A novel IFIH1 mutation in the pincer domain underlies the clinical features of both Aicardi-Goutières and Singleton-Merten syndromes in a single patient.

Takeichi T, Katayama C, Tanaka T, Okuno Y, Murakami N, Kono M, Sugiura K, Aoyama Y, Akiyama M.

Br J Dermatol. 2018 Feb;178(2):e111-e113. doi: 10.1111/bjd.15869. Epub 2017 Dec 22. No abstract available.

PMID:
29270977
37.

Adjuvant chemotherapy improves survival of patients with high-risk upper urinary tract urothelial carcinoma: a propensity score-matched analysis.

Fujita K, Taneishi K, Inamoto T, Ishizuya Y, Takada S, Tsujihata M, Tanigawa G, Minato N, Nakazawa S, Takada T, Iwanishi T, Uemura M, Okuno Y, Azuma H, Norio N.

BMC Urol. 2017 Dec 1;17(1):110. doi: 10.1186/s12894-017-0305-4.

38.

Antimutagenic activity of flavonoids from Sozuku.

Okuno Y, Marumoto S, Miyazawa M.

Nat Prod Res. 2017 Nov 28:1-4. doi: 10.1080/14786419.2017.1408104. [Epub ahead of print]

PMID:
29183163
39.

Analysis of the evidence-practice gap to facilitate proper medical care for the elderly: investigation, using databases, of utilization measures for National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB).

Nakayama T, Imanaka Y, Okuno Y, Kato G, Kuroda T, Goto R, Tanaka S, Tamura H, Fukuhara S, Fukuma S, Muto M, Yanagita M, Yamamoto Y; BiDAME: Big Data Analysis of Medical Care for the Elderly in Kyoto.

Environ Health Prev Med. 2017 Jun 6;22(1):51. doi: 10.1186/s12199-017-0644-5.

40.

Isolated Pancreatic Myeloid Sarcoma Associated with t(8;21)/RUNX1-RUNX1T1 Rearrangement.

Tokunaga K, Yamamura A, Ueno S, Kikukawa Y, Yamaguchi S, Hidaka M, Matsuno N, Kawaguchi T, Matsuoka M, Okuno Y.

Intern Med. 2018 Feb 15;57(4):563-568. doi: 10.2169/internalmedicine.8912-17. Epub 2017 Nov 20.

41.

Analysis of the glycoproteins of Seoul orthohantavirus strain B1 associated with fusion activity.

Isegawa Y, Okuno Y.

Arch Virol. 2018 Feb;163(2):419-425. doi: 10.1007/s00705-017-3623-7. Epub 2017 Nov 3.

PMID:
29101537
42.

Machine learning accelerates MD-based binding pose prediction between ligands and proteins.

Terayama K, Iwata H, Araki M, Okuno Y, Tsuda K.

Bioinformatics. 2018 Mar 1;34(5):770-778. doi: 10.1093/bioinformatics/btx638.

43.

Associations of Perceived Mental Stress, Sense of Purpose in Life, and Negative Life Events With the Risk of Incident Herpes Zoster and Postherpetic Neuralgia: The SHEZ Study.

Takao Y, Okuno Y, Mori Y, Asada H, Yamanishi K, Iso H.

Am J Epidemiol. 2018 Feb 1;187(2):251-259. doi: 10.1093/aje/kwx249.

PMID:
29036443
44.

Comparison of Essential Oils from Three Kinds of Cryptotaenia japonica Hassk (Kirimitsuba, Nemitsuba, and Itomitsuba) used in Japanese Food.

Okuno Y, Marumoto S, Miyazawa M.

J Oleo Sci. 2017 Nov 1;66(11):1273-1276. doi: 10.5650/jos.ess17133. Epub 2017 Oct 11.

45.

Comprehensive detection of viruses in pediatric patients with acute liver failure using next-generation sequencing.

Suzuki T, Kawada JI, Okuno Y, Hayano S, Horiba K, Torii Y, Takahashi Y, Umetsu S, Sogo T, Inui A, Ito Y.

J Clin Virol. 2017 Nov;96:67-72. doi: 10.1016/j.jcv.2017.10.001. Epub 2017 Oct 3.

PMID:
28992518
46.

Genetic heterogeneity of uncharacterized childhood autoimmune diseases with lymphoproliferation.

Takagi M, Hoshino A, Yoshida K, Ueno H, Imai K, Piao J, Kanegane H, Yamashita M, Okano T, Muramatsu H, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Hayashi Y, Kojima S, Morio T.

Pediatr Blood Cancer. 2018 Feb;65(2). doi: 10.1002/pbc.26831. Epub 2017 Sep 29.

PMID:
28960754
47.

Comprehensive genetic analysis of donor cell derived leukemia with KMT2A rearrangement.

Taniguchi R, Muramatsu H, Okuno Y, Suzuki K, Obu S, Nakatochi M, Shimamura T, Takahashi Y, Horikoshi Y, Watanabe K, Kojima S.

Pediatr Blood Cancer. 2018 Feb;65(2). doi: 10.1002/pbc.26823. Epub 2017 Sep 17.

PMID:
28921816
48.

Inhibition of influenza virus replication by adlay tea.

Nagai E, Iwai M, Koketsu R, Sogabe R, Morimoto R, Suzuki Y, Ohta Y, Okuno Y, Ohshima A, Enomoto T, Isegawa Y.

J Sci Food Agric. 2018 Mar;98(5):1899-1905. doi: 10.1002/jsfa.8671. Epub 2017 Oct 12.

PMID:
28902408
49.

Biallelic mutations in SZT2 cause a discernible clinical entity with epilepsy, developmental delay, macrocephaly and a dysmorphic corpus callosum.

Nakamura Y, Togawa Y, Okuno Y, Muramatsu H, Nakabayashi K, Kuroki Y, Ieda D, Hori I, Negishi Y, Togawa T, Hattori A, Kojima S, Saitoh S.

Brain Dev. 2018 Feb;40(2):134-139. doi: 10.1016/j.braindev.2017.08.003. Epub 2017 Oct 12.

PMID:
28893434
50.

Exome Sequencing Landscape Analysis in Ovarian Clear Cell Carcinoma Shed Light on Key Chromosomal Regions and Mutation Gene Networks.

Murakami R, Matsumura N, Brown JB, Higasa K, Tsutsumi T, Kamada M, Abou-Taleb H, Hosoe Y, Kitamura S, Yamaguchi K, Abiko K, Hamanishi J, Baba T, Koshiyama M, Okuno Y, Yamada R, Matsuda F, Konishi I, Mandai M.

Am J Pathol. 2017 Oct;187(10):2246-2258. doi: 10.1016/j.ajpath.2017.06.012. Epub 2017 Sep 6.

PMID:
28888422

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