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Items: 1 to 50 of 987

1.

Corrigendum to "Frequent intragenic microdeletions of elastin in familial supravalvular aortic stenosis." [Int. J. Cardiol., 274 (2019) 290-295].

Hayano S, Okuno Y, Tsutsumi M, Inagaki H, Fukasawa Y, Kurahashi H, Kojima S, Takahashi Y, Kato T.

Int J Cardiol. 2019 Jun 27. pii: S0167-5273(19)33016-5. doi: 10.1016/j.ijcard.2019.06.020. [Epub ahead of print] No abstract available.

PMID:
31256992
2.

DOCK8 mutation diagnosed using whole-exome sequencing of the dried blood spot-derived DNA: a case report of an Iraqi girl diagnosed in Japan.

Al-Kzayer LFY, Al-Aradi HMH, Shigemura T, Sano K, Tanaka M, Hamada M, Ali KH, Aldaghir OM, Nakazawa Y, Okuno Y.

BMC Med Genet. 2019 Jun 26;20(1):114. doi: 10.1186/s12881-019-0837-4.

3.

Essential role of PTPN11 mutation in enhanced haematopoietic differentiation potential of induced pluripotent stem cells of juvenile myelomonocytic leukaemia.

Shigemura T, Matsuda K, Kurata T, Sakashita K, Okuno Y, Muramatsu H, Yue F, Ebihara Y, Tsuji K, Sasaki K, Nakahata T, Nakazawa Y, Koike K.

Br J Haematol. 2019 Jun 20. doi: 10.1111/bjh.16060. [Epub ahead of print]

PMID:
31222725
4.

Alteration in ventricular pressure stimulates cardiac repair and remodeling.

Unno K, Oikonomopoulos A, Fujikawa Y, Okuno Y, Narita S, Kato T, Hayashida R, Kondo K, Shibata R, Murohara T, Yang Y, Dangwal S, Sereti KI, Yiling Q, Johnson K, Jha A, Sosnovik DE, Fann Y, Liao R.

J Mol Cell Cardiol. 2019 Aug;133:174-187. doi: 10.1016/j.yjmcc.2019.06.006. Epub 2019 Jun 17.

PMID:
31220468
5.

The rapid improvement in visual field defect observed with weekly perimetry during intensity-modulated radiotherapy for optic nerve sheath meningioma.

Inoue T, Mimura O, Ikenaga K, Okuno Y, Nishiguchi I.

Int Cancer Conf J. 2019 Apr 6;8(3):136-140. doi: 10.1007/s13691-019-00371-9. eCollection 2019 Jul.

6.

Targetable driver mutations in multicentric reticulohistiocytosis.

Murakami N, Sakai T, Arai E, Muramatsu H, Ichikawa D, Asai S, Shimoyama Y, Ishiguro N, Takahashi Y, Okuno Y, Nishida Y.

Haematologica. 2019 Jun 6. pii: haematol.2019.218735. doi: 10.3324/haematol.2019.218735. [Epub ahead of print]

7.

Laser- and cryogenic probe-assisted NMR enables hypersensitive analysis of biomolecules at submicromolar concentration.

Okuno Y, Mecha MF, Yang H, Zhu L, Fry CG, Cavagnero S.

Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11602-11611. doi: 10.1073/pnas.1820573116. Epub 2019 May 29.

PMID:
31142651
8.

Polypharmacy in >75-year-Old Patients on Admission to Tokyo-Area Hospitals.

Momo K, Yasu T, Hayashi D, Saitoh M, Ito Y, Yashiro Y, Nagumo J, Seki R, Furuya J, Okuno Y, Horii T, Abe K, Shirota M.

Am J Ther. 2019 May 20. doi: 10.1097/MJT.0000000000000889. [Epub ahead of print] No abstract available.

PMID:
31135386
9.

Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations.

Ikemura S, Yasuda H, Matsumoto S, Kamada M, Hamamoto J, Masuzawa K, Kobayashi K, Manabe T, Arai D, Nakachi I, Kawada I, Ishioka K, Nakamura M, Namkoong H, Naoki K, Ono F, Araki M, Kanada R, Ma B, Hayashi Y, Mimaki S, Yoh K, Kobayashi SS, Kohno T, Okuno Y, Goto K, Tsuchihara K, Soejima K.

Proc Natl Acad Sci U S A. 2019 May 14;116(20):10025-10030. doi: 10.1073/pnas.1819430116. Epub 2019 May 1.

10.

Elucidation of the pathogenic mechanism and potential treatment strategy for a female patient with spastic paraplegia derived from a single-nucleotide deletion in PLP1.

Yamamoto-Shimojima K, Imaizumi T, Aoki Y, Inoue K, Kaname T, Okuno Y, Muramatsu H, Kato K, Yamamoto T.

J Hum Genet. 2019 Jul;64(7):665-671. doi: 10.1038/s10038-019-0600-x. Epub 2019 Apr 19.

PMID:
31004103
11.

Repertoires of G protein-coupled receptors for Ciona-specific neuropeptides.

Shiraishi A, Okuda T, Miyasaka N, Osugi T, Okuno Y, Inoue J, Satake H.

Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7847-7856. doi: 10.1073/pnas.1816640116. Epub 2019 Apr 1.

12.

Inflammation and Hypervascularization in a Large Animal Model of Knee Osteoarthritis: Imaging with Pathohistologic Correlation.

Korchi AM, Cengarle-Samak A, Okuno Y, Martel-Pelletier J, Pelletier JP, Boesen M, Doyon J, Bodson-Clermont P, Lussier B, Héon H, Sapoval M, Bureau NJ, Soulez G.

J Vasc Interv Radiol. 2019 Jul;30(7):1116-1127. doi: 10.1016/j.jvir.2018.09.031. Epub 2019 Mar 29.

PMID:
30935868
13.

Structural modification of indomethacin toward selective inhibition of COX-2 with a significant increase in van der Waals contributions.

Ikeda A, Funakoshi E, Araki M, Ma B, Karuo Y, Tarui A, Sato K, Okuno Y, Kawai K, Omote M.

Bioorg Med Chem. 2019 May 1;27(9):1789-1794. doi: 10.1016/j.bmc.2019.03.021. Epub 2019 Mar 14.

PMID:
30898436
14.

KLF1 mutation E325K induces cell cycle arrest in erythroid cells differentiated from congenital dyserythropoietic anemia patient-specific induced pluripotent stem cells.

Kohara H, Utsugisawa T, Sakamoto C, Hirose L, Ogawa Y, Ogura H, Sugawara A, Liao J, Aoki T, Iwasaki T, Asai T, Doisaki S, Okuno Y, Muramatsu H, Abe T, Kurita R, Miyamoto S, Sakuma T, Shiba M, Yamamoto T, Ohga S, Yoshida K, Ogawa S, Ito E, Kojima S, Kanno H, Tani K.

Exp Hematol. 2019 May;73:25-37.e8. doi: 10.1016/j.exphem.2019.03.001. Epub 2019 Mar 12.

PMID:
30876823
15.

Aberrant Active cis-Regulatory Elements Associated with Downregulation of RET Finger Protein Overcome Chemoresistance in Glioblastoma.

Ranjit M, Hirano M, Aoki K, Okuno Y, Ohka F, Yamamichi A, Kato A, Maeda S, Motomura K, Matsuo K, Enomoto A, Ino Y, Todo T, Takahashi M, Wakabayashi T, Kato T, Natsume A.

Cell Rep. 2019 Feb 26;26(9):2274-2281.e5. doi: 10.1016/j.celrep.2019.01.109.

16.

Dynamic Docking of a Medium-Sized Molecule to Its Receptor by Multicanonical MD Simulations.

Bekker GJ, Araki M, Oshima K, Okuno Y, Kamiya N.

J Phys Chem B. 2019 Mar 21;123(11):2479-2490. doi: 10.1021/acs.jpcb.8b12419. Epub 2019 Mar 12.

PMID:
30808168
17.

Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients.

Mori M, Hira A, Yoshida K, Muramatsu H, Okuno Y, Shiraishi Y, Anmae M, Yasuda J, Tadaka S, Kinoshita K, Osumi T, Noguchi Y, Adachi S, Kobayashi R, Kawabata H, Imai K, Morio T, Tamura K, Takaori-Kondo A, Yamamoto M, Miyano S, Kojima S, Ito E, Ogawa S, Matsuo K, Yabe H, Yabe M, Takata M.

Haematologica. 2019 Feb 21. pii: haematol.2018.207241. doi: 10.3324/haematol.2018.207241. [Epub ahead of print]

18.

A Syrian Refugee in Iraq Diagnosed as a Case of IL12RB1 Deficiency in Japan Using Dried Blood Spots.

Al-Kzayer LFY, Yassin AK, Salih KH, Shigemura T, Sano K, Al-Simaani RBY, Tanaka M, Nakazawa Y, Okuno Y.

Front Immunol. 2019 Jan 25;10:58. doi: 10.3389/fimmu.2019.00058. eCollection 2019.

19.

Combination treatment with highly bioavailable curcumin and NQO1 inhibitor exhibits potent antitumor effects on esophageal squamous cell carcinoma.

Mizumoto A, Ohashi S, Kamada M, Saito T, Nakai Y, Baba K, Hirohashi K, Mitani Y, Kikuchi O, Matsubara J, Yamada A, Takahashi T, Lee H, Okuno Y, Kanai M, Muto M.

J Gastroenterol. 2019 Feb 8. doi: 10.1007/s00535-019-01549-x. [Epub ahead of print]

PMID:
30737573
20.

Suppression of IgE-Independent Degranulation of Murine Connective Tissue-Type Mast Cells by Dexamethasone.

Yamada K, Sato H, Sakamaki K, Kamada M, Okuno Y, Fukuishi N, Furuta K, Tanaka S.

Cells. 2019 Feb 1;8(2). pii: E112. doi: 10.3390/cells8020112.

21.

Publisher Correction: Defective Epstein-Barr virus in chronic active infection and haematological malignancy.

Okuno Y, Murata T, Sato Y, Muramatsu H, Ito Y, Watanabe T, Okuno T, Murakami N, Yoshida K, Sawada A, Inoue M, Kawa K, Seto M, Ohshima K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Narita Y, Yoshida M, Goshima F, Kawada JI, Nishida T, Kiyoi H, Kato S, Nakamura S, Morishima S, Yoshikawa T, Fujiwara S, Shimizu N, Isobe Y, Noguchi M, Kikuta A, Iwatsuki K, Takahashi Y, Kojima S, Ogawa S, Kimura H.

Nat Microbiol. 2019 Mar;4(3):544. doi: 10.1038/s41564-019-0387-8.

PMID:
30705423
22.

Defective Epstein-Barr virus in chronic active infection and haematological malignancy.

Okuno Y, Murata T, Sato Y, Muramatsu H, Ito Y, Watanabe T, Okuno T, Murakami N, Yoshida K, Sawada A, Inoue M, Kawa K, Seto M, Ohshima K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Narita Y, Yoshida M, Goshima F, Kawada JI, Nishida T, Kiyoi H, Kato S, Nakamura S, Morishima S, Yoshikawa T, Fujiwara S, Shimizu N, Isobe Y, Noguchi M, Kikuta A, Iwatsuki K, Takahashi Y, Kojima S, Ogawa S, Kimura H.

Nat Microbiol. 2019 Mar;4(3):404-413. doi: 10.1038/s41564-018-0334-0. Epub 2019 Jan 21. Erratum in: Nat Microbiol. 2019 Jan 30;:.

PMID:
30664667
23.

Prediction of ALK mutations mediating ALK-TKIs resistance and drug re-purposing to overcome the resistance.

Okada K, Araki M, Sakashita T, Ma B, Kanada R, Yanagitani N, Horiike A, Koike S, Oh-Hara T, Watanabe K, Tamai K, Maemondo M, Nishio M, Ishikawa T, Okuno Y, Fujita N, Katayama R.

EBioMedicine. 2019 Mar;41:105-119. doi: 10.1016/j.ebiom.2019.01.019. Epub 2019 Jan 17.

24.

Sleep Shortage Is Associated With Postherpetic Neuralgia Development Through Hyperesthesia and Acute Pain Intensity: A Community-Based Prospective Cohort Study.

Yamada K, Kubota Y, Shimizu Y, Cui R, Mori Y, Okuno Y, Asada H, Yamanishi K, Iso H; SHEZ Study Group.

Pain Pract. 2019 Jun;19(5):476-483. doi: 10.1111/papr.12766. Epub 2019 Feb 28.

PMID:
30659740
25.

Therapy-related acute myeloid leukemia after chemotherapy in extensive disease-small cell lung cancer.

Ueda N, Fujita K, Okuno Y, Nakatani K, Mio T.

Clin Case Rep. 2018 Nov 19;7(1):100-103. doi: 10.1002/ccr3.1931. eCollection 2019 Jan.

26.

Adipocyte GR Inhibits Healthy Adipose Expansion Through Multiple Mechanisms in Cushing Syndrome.

Hayashi R, Okuno Y, Mukai K, Kitamura T, Hayakawa T, Onodera T, Murata M, Fukuhara A, Imamura R, Miyagawa Y, Nonomura N, Otsuki M, Shimomura I.

Endocrinology. 2019 Mar 1;160(3):504-521. doi: 10.1210/en.2018-01029.

PMID:
30649271
27.

Potential anti-lymphoma effect of M-CSFR inhibitor in adult T-cell leukemia/lymphoma.

Komohara Y, Noyori O, Saito Y, Takeya H, Baghdadi M, Kitagawa F, Hama N, Ishikawa K, Okuno Y, Nosaka K, Seino KI, Matsuoka M, Suzu S.

J Clin Exp Hematop. 2018;58(4):152-160. doi: 10.3960/jslrt.18034.

28.

Improving the Accuracy of Protein-Ligand Binding Mode Prediction Using a Molecular Dynamics-Based Pocket Generation Approach.

Araki M, Iwata H, Ma B, Fujita A, Terayama K, Sagae Y, Ono F, Tsuda K, Kamiya N, Okuno Y.

J Comput Chem. 2018 Dec 15;39(32):2679-2689. doi: 10.1002/jcc.25715.

PMID:
30515903
29.

Regulation of Epstein-Barr Virus Life Cycle and Cell Proliferation by Histone H3K27 Methyltransferase EZH2 in Akata Cells.

Ichikawa T, Okuno Y, Sato Y, Goshima F, Yoshiyama H, Kanda T, Kimura H, Murata T.

mSphere. 2018 Nov 28;3(6). pii: e00478-18. doi: 10.1128/mSphere.00478-18.

30.

Effect of Transcatheter Arterial Microembolization on Phantom Limb Pain Persisting for 17 Years.

Shibuya M, Yamamoto M, Okuno Y.

Cardiovasc Intervent Radiol. 2019 Mar;42(3):471-474. doi: 10.1007/s00270-018-2109-7. Epub 2018 Nov 13.

PMID:
30426150
31.

MUC1/KL-6 expression confers an aggressive phenotype upon myeloma cells.

Endo S, Nishimura N, Kawano Y, Ueno N, Ueno S, Tatetsu H, Komohara Y, Takeya M, Hata H, Mitsuya H, Masao M, Okuno Y.

Biochem Biophys Res Commun. 2018 Dec 9;507(1-4):246-252. doi: 10.1016/j.bbrc.2018.11.016. Epub 2018 Nov 10.

PMID:
30420285
32.

A simple quantitative chiral analysis of amino acid esters by fluorine-19 nuclear magnetic resonance using the modified James-Bull method.

Hamaguchi N, Okuno Y, Oe Y, Ohta T.

Chirality. 2019 Jan;31(1):34-40. doi: 10.1002/chir.23028. Epub 2018 Nov 5.

PMID:
30395695
33.

Dopamine and Serotonin Receptors Cooperatively Modulate Pacemaker Activity of Intestinal Cells of Cajal.

Liu HN, Hirata H, Okuno Y, Okabe M, Furukawa K.

Chin J Physiol. 2018 Oct 31;61(5):302-312. doi: 10.4077/CJP.2018.BAH607.

PMID:
30384551
34.

Associations of complementation group, ALDH2 genotype, and clonal abnormalities with hematological outcome in Japanese patients with Fanconi anemia.

Yabe M, Koike T, Ohtsubo K, Imai E, Morimoto T, Takakura H, Koh K, Yoshida K, Ogawa S, Ito E, Okuno Y, Muramatsu H, Kojima S, Matsuo K, Mori M, Hira A, Takata M, Yabe H.

Ann Hematol. 2019 Feb;98(2):271-280. doi: 10.1007/s00277-018-3517-0. Epub 2018 Oct 27.

PMID:
30368588
35.

Base-to-apex gradient pattern of cardiac impairment identified on myocardial T1 mapping in cardiac amyloidosis.

Oda S, Kawano Y, Okuno Y, Utsunomiya D, Nakaura T, Tsujita K, Yamashita Y.

Radiol Case Rep. 2018 Oct 18;14(1):72-74. doi: 10.1016/j.radcr.2018.09.025. eCollection 2019 Jan.

36.

Fibronectin type III domain-containing protein 5 interacts with APP and decreases amyloid β production in Alzheimer's disease.

Noda Y, Kuzuya A, Tanigawa K, Araki M, Kawai R, Ma B, Sasakura Y, Maesako M, Tashiro Y, Miyamoto M, Uemura K, Okuno Y, Kinoshita A.

Mol Brain. 2018 Oct 24;11(1):61. doi: 10.1186/s13041-018-0401-8.

37.

Reduction of stratum corneum ceramides in Neu-Laxova syndrome caused by phosphoglycerate dehydrogenase deficiency.

Takeichi T, Okuno Y, Kawamoto A, Inoue T, Nagamoto E, Murase C, Shimizu E, Tanaka K, Kageshita Y, Fukushima S, Kono M, Ishikawa J, Ihn H, Takahashi Y, Akiyama M.

J Lipid Res. 2018 Dec;59(12):2413-2420. doi: 10.1194/jlr.P087536. Epub 2018 Oct 22.

PMID:
30348640
38.

Modification of cellular and humoral immunity by somatically reverted T cells in X-linked lymphoproliferative syndrome type 1.

Hoshino A, Yang X, Tanita K, Yoshida K, Ono T, Nishida N, Okuno Y, Kanzaki T, Goi K, Fujino H, Ohshima K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Kojima S, Morio T, Kanegane H.

J Allergy Clin Immunol. 2019 Jan;143(1):421-424.e11. doi: 10.1016/j.jaci.2018.07.044. Epub 2018 Oct 17. No abstract available.

PMID:
30342818
39.

Gain-of-function IKBKB mutation causes human combined immune deficiency.

Cardinez C, Miraghazadeh B, Tanita K, da Silva E, Hoshino A, Okada S, Chand R, Asano T, Tsumura M, Yoshida K, Ohnishi H, Kato Z, Yamazaki M, Okuno Y, Miyano S, Kojima S, Ogawa S, Andrews TD, Field MA, Burgio G, Morio T, Vinuesa CG, Kanegane H, Cook MC.

J Exp Med. 2018 Nov 5;215(11):2715-2724. doi: 10.1084/jem.20180639. Epub 2018 Oct 18.

40.

A Platform for Comprehensive Genomic Profiling in Human Cancers and Pharmacogenomics Therapy Selection.

Kou T, Kanai M, Kamada M, Nakatsui M, Matsumoto S, Okuno Y, Muto M.

Methods Mol Biol. 2018;1825:413-424. doi: 10.1007/978-1-4939-8639-2_14.

PMID:
30334215
41.

Prediction of prostate cancer by deep learning with multilayer artificial neural network.

Takeuchi T, Hattori-Kato M, Okuno Y, Iwai S, Mikami K.

Can Urol Assoc J. 2019 May;13(5):E145-E150. doi: 10.5489/cuaj.5526. Epub 2018 Oct 15.

42.

Impact of MR on mature adipocytes in high-fat/high-sucrose diet-induced obesity

Hayakawa T, Minemura T, Onodera T, Shin J, Okuno Y, Fukuhara A, Otsuki M, Shimomura I.

J Endocrinol. 2018 Oct 1;239(1):63–71. doi: 10.1530/JOE-18-0026.

PMID:
30307154
43.

Convulsive seizure and pulmonary edema during hyperbaric oxygen therapy:A case report.

Cho K, Minami T, Okuno Y, Kakuda Y, Tsutsumi T, Kogame T, Ohtsuru S, Sato N, Koike K.

J Med Invest. 2018;65(3.4):286-288. doi: 10.2152/jmi.65.286.

44.

Frequent intragenic microdeletions of elastin in familial supravalvular aortic stenosis.

Hayano S, Okuno Y, Tsutsumi M, Inagaki H, Fukasawa Y, Kurahashi H, Kojima S, Takahashi Y, Kato T.

Int J Cardiol. 2019 Jan 1;274:290-295. doi: 10.1016/j.ijcard.2018.09.032. Epub 2018 Sep 13. Erratum in: Int J Cardiol. 2019 Jun 27;:.

PMID:
30228022
45.

Biotransformation of (+)-Carvone and (-)-Carvone by the Common Cutworm Spodoptera litura Larvae.

Marumoto S, Okuno Y, Hagiwara Y, Miyazawa M.

J Oleo Sci. 2018 Oct 11;67(10):1253-1257. doi: 10.5650/jos.ess18105. Epub 2018 Sep 13.

46.

Impaired glucagon secretion in patients with fulminant type 1 diabetes mellitus.

Komada H, Hirota Y, Sakaguchi K, Okuno Y, Ogawa W, Seino S.

Endocrine. 2019 Mar;63(3):476-479. doi: 10.1007/s12020-018-1750-x. Epub 2018 Sep 10.

PMID:
30203124
47.

De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome.

Toki T, Yoshida K, Wang R, Nakamura S, Maekawa T, Goi K, Katoh MC, Mizuno S, Sugiyama F, Kanezaki R, Uechi T, Nakajima Y, Sato Y, Okuno Y, Sato-Otsubo A, Shiozawa Y, Kataoka K, Shiraishi Y, Sanada M, Chiba K, Tanaka H, Terui K, Sato T, Kamio T, Sakaguchi H, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Kanno H, Miyano S, Kojima S, Ishiguro A, Sugita K, Kenmochi N, Takahashi S, Eto K, Ogawa S, Ito E.

Am J Hum Genet. 2018 Sep 6;103(3):440-447. doi: 10.1016/j.ajhg.2018.07.020. Epub 2018 Aug 23.

48.

Reliable patient-reported outcome measure and survivorship of UKA for primary spontaneous osteonecrosis.

Kaneko T, Kono N, Sunakawa T, Okuno Y, Ikegami H, Musha Y.

Eur J Orthop Surg Traumatol. 2019 Jan;29(1):119-124. doi: 10.1007/s00590-018-2296-6. Epub 2018 Aug 23.

PMID:
30141028
49.

Integration Mapping of piggyBac-Mediated CD19 Chimeric Antigen Receptor T Cells Analyzed by Novel Tagmentation-Assisted PCR.

Hamada M, Nishio N, Okuno Y, Suzuki S, Kawashima N, Muramatsu H, Tsubota S, Wilson MH, Morita D, Kataoka S, Ichikawa D, Murakami N, Taniguchi R, Suzuki K, Kojima D, Sekiya Y, Nishikawa E, Narita A, Hama A, Kojima S, Nakazawa Y, Takahashi Y.

EBioMedicine. 2018 Aug;34:18-26. doi: 10.1016/j.ebiom.2018.07.008. Epub 2018 Aug 3.

50.

Biological and epidemiological evidence of anti-allergic effects of traditional Japanese food ume (Prunus mume).

Kono R, Nakamura M, Nomura S, Kitano N, Kagiya T, Okuno Y, Inada KI, Tokuda A, Utsunomiya H, Ueno M.

Sci Rep. 2018 Aug 3;8(1):11638. doi: 10.1038/s41598-018-30086-5.

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