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Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease.

Fajgenbaum DC, Langan RA, Sada Japp A, Partridge HL, Pierson SK, Singh A, Arenas DJ, Ruth JR, Nabel CS, Stone K, Okumura M, Schwarer A, Jose FF, Hamerschlak N, Wertheim GB, Jordan MB, Cohen AD, Krymskaya V, Rubenstein A, Betts MR, Kambayashi T, van Rhee F, Uldrick TS.

J Clin Invest. 2019 Aug 13;130. pii: 126091. doi: 10.1172/JCI126091.


Sensitivity of Deinococcus grandis rodZ deletion mutant to calcium ions results in enhanced spheroplast size.

Morita Y, Okumura M, Narumi I, Nishida H.

AIMS Microbiol. 2019 Jun 26;5(2):176-185. doi: 10.3934/microbiol.2019.2.176. eCollection 2019.


Venous thromboembolism prophylaxis in thoracic surgery patients: an international survey.

Shargall Y, Brunelli A, Murthy S, Schneider L, Minervini F, Bertolaccini L, Agzarian J, Linkins LA, Kestenholz P, Li H, Rocco G, Girard P, Venuta F, Samama M, Scarci M, Anraku M, Falcoz PE, Kirk A, Solli P, Hofstetter W, Okumura M, Douketis J, Litle V.

Eur J Cardiothorac Surg. 2019 Jul 30. pii: ezz191. doi: 10.1093/ejcts/ezz191. [Epub ahead of print]


A Multi-Hemagglutinin-Based Enzyme-Linked Immunosorbent Assay to Serologically Detect Influenza A Virus Infection in Animals.

Okumura M, Takenaka-Uema A, Murakami S, Horimoto T.

Vet Sci. 2019 Jul 22;6(3). pii: E64. doi: 10.3390/vetsci6030064.


Lower physical activity is associated with daytime sleepiness in children aged 9-12 years.

Isa T, Sugimoto T, Murata S, Tsuboi Y, Ebina A, Kondo Y, Torizawa K, Okumura M, Shigemoto C, Matsuda N, Misu S, Ono R.

J Child Health Care. 2019 Jul 21:1367493519864756. doi: 10.1177/1367493519864756. [Epub ahead of print]


Mortality from extrathymic malignancy after thymic tumour resections: incidences and risk factors.

Hamaji M, Sozu T, Machida R, Watanabe SI, Yoshida K, Toyooka S, Tanahashi M, Kondo K, Horio H, Okumura M, Date H.

Interact Cardiovasc Thorac Surg. 2019 Jul 21. pii: ivz177. doi: 10.1093/icvts/ivz177. [Epub ahead of print]


Association Between Public Transportation Use and Loneliness Among Urban Elderly People Who Stop Driving.

Matsuda N, Murata S, Torizawa K, Isa T, Ebina A, Kondo Y, Tsuboi Y, Fukuta A, Okumura M, Shigemoto C, Ono R.

Gerontol Geriatr Med. 2019 Jul 13;5:2333721419851293. doi: 10.1177/2333721419851293. eCollection 2019 Jan-Dec.


Validation of Eurolung risk models in a Japanese population: a retrospective single-centre analysis of 612 cases.

Nagoya A, Kanzaki R, Kanou T, Ose N, Funaki S, Minami M, Shintani Y, Tsutsui A, Suga S, Tajima T, Ohno Y, Okumura M.

Interact Cardiovasc Thorac Surg. 2019 Jul 16. pii: ivz171. doi: 10.1093/icvts/ivz171. [Epub ahead of print]


Diverse Structural Conversion and Aggregation Pathways of Alzheimer's Amyloid-β (1-40).

Lin Y, Sahoo BR, Ozawa D, Kinoshita M, Kang J, Lim MH, Okumura M, Huh YH, Moon E, Jang JH, Lee HJ, Ryu KY, Ham S, Won HS, Ryu KS, Sugiki T, Bang JK, Hoe HS, Fujiwara T, Ramamoorthy A, Lee YH.

ACS Nano. 2019 Jul 24. doi: 10.1021/acsnano.9b01578. [Epub ahead of print]


Outcomes following balloon dilation for management of urethral obstruction secondary to urothelial carcinoma in dogs: 12 cases (2010-2015).

Kim S, Hosoya K, Takagi S, Okumura M.

J Am Vet Med Assoc. 2019 Aug 1;255(3):330-335. doi: 10.2460/javma.255.3.330.


Adipose Tissue-Derived Stem Cells Have the Ability to Differentiate into Alveolar Epithelial Cells and Ameliorate Lung Injury Caused by Elastase-Induced Emphysema in Mice.

Fukui E, Funaki S, Kimura K, Momozane T, Kimura A, Chijimatsu R, Kanzaki R, Kanou T, Ose N, Minami M, Miyagawa S, Sawa Y, Okumura M, Shintani Y.

Stem Cells Int. 2019 Jun 10;2019:5179172. doi: 10.1155/2019/5179172. eCollection 2019.


Analysis of A4gnt Knockout Mice Reveals an Essential Role for Gastric Sulfomucins in Preventing Gastritis Cystica Profunda.

Kawakubo M, Komura H, Goso Y, Okumura M, Sato Y, Fujii C, Miyashita M, Arisaka N, Harumiya S, Yamanoi K, Yamada S, Kakuta S, Kawashima H, Fukuda MN, Fukuda M, Nakayama J.

J Histochem Cytochem. 2019 Jun 27:22155419860134. doi: 10.1369/0022155419860134. [Epub ahead of print]


Synthesis of (±)-Idarubicinone via Global Functionalization of Tetracene.

Dennis DG, Okumura M, Sarlah D.

J Am Chem Soc. 2019 Jul 3;141(26):10193-10198. doi: 10.1021/jacs.9b05370. Epub 2019 Jun 19.


The impact of the offset distance between the planning target volume and isocenter on irradiation time in TomoTherapy: A phantom study.

Hirata M, Hanaoka K, Matsumoto K, Tamura M, Okumura M, Monzen H.

Phys Med. 2019 Jul;63:19-24. doi: 10.1016/j.ejmp.2019.05.009. Epub 2019 May 25.


Hypofractionated proton beam therapy for centrally located lung cancer.

Nakamura N, Hotta K, Zenda S, Baba H, Kito S, Akita T, Motegi A, Hojo H, Nakamura M, Parshuram RV, Okumura M, Akimoto T.

J Med Imaging Radiat Oncol. 2019 Aug;63(4):552-556. doi: 10.1111/1754-9485.12901. Epub 2019 May 30.


Interrelational changes in the epidemiology and clinical features of nontuberculous mycobacterial pulmonary disease and tuberculosis in a referral hospital in Japan.

Furuuchi K, Morimoto K, Yoshiyama T, Tanaka Y, Fujiwara K, Okumura M, Izumi K, Shiraishi Y, Mitarai S, Ogata H, Kurashima A, Yoshimori K, Ohta K, Goto H, Sasaki Y.

Respir Med. 2019 Jun;152:74-80. doi: 10.1016/j.rmed.2019.05.001. Epub 2019 May 8.


Limited benefit of CT scans in tuberculosis contact tracing.

Yoshiyama T, Kurosaki A, Ogata H, Sasaki Y, Okumura M.

J Infect Chemother. 2019 May 14. pii: S1341-321X(18)30326-X. doi: 10.1016/j.jiac.2019.03.023. [Epub ahead of print]


Palladium-Catalyzed Dearomative syn-1,4-Carboamination with Grignard Reagents.

Tang C, Okumura M, Zhu Y, Hooper AR, Zhou Y, Lee YH, Sarlah D.

Angew Chem Int Ed Engl. 2019 Jul 22;58(30):10245-10249. doi: 10.1002/anie.201905021. Epub 2019 Jun 24.


Temperature Dependence of the Reaction of Chlorine Atoms with CH3OH and CH3CHO.

Hui AO, Okumura M, Sander SP.

J Phys Chem A. 2019 Jun 13;123(23):4964-4972. doi: 10.1021/acs.jpca.9b00038. Epub 2019 May 30.


Serotonergic modulation of feeding behavior in Caenorhabditis elegans and other related nematodes.

Ishita Y, Chihara T, Okumura M.

Neurosci Res. 2019 Apr 24. pii: S0168-0102(19)30076-8. doi: 10.1016/j.neures.2019.04.006. [Epub ahead of print] Review.


Associations of coronary plaque characteristics by integrated backscatter intravascular ultrasound with detectability of vessel external elastic lamina using optical frequency domain imaging in human coronary arteries: A sub-analysis of the MISTIC-1 trial.

Ishikawa M, Muramatsu T, Nanasato M, Nagasaka R, Takatsu H, Yoshiki Y, Hashimoto Y, Ohota M, Okumura M, Naruse H, Ishii J, Ito K, Takahashi H, Kamiya H, Yoshida Y, Ozaki Y.

Catheter Cardiovasc Interv. 2019 Apr 25. doi: 10.1002/ccd.28218. [Epub ahead of print]


Reply to Tian et al.

Okumura M.

Eur J Cardiothorac Surg. 2019 Apr 21. pii: ezz121. doi: 10.1093/ejcts/ezz121. [Epub ahead of print] No abstract available.


Dynamic assembly of protein disulfide isomerase in catalysis of oxidative folding.

Okumura M, Noi K, Kanemura S, Kinoshita M, Saio T, Inoue Y, Hikima T, Akiyama S, Ogura T, Inaba K.

Nat Chem Biol. 2019 May;15(5):499-509. doi: 10.1038/s41589-019-0268-8. Epub 2019 Apr 15.


The Protein Disulfide Isomerase Family: from proteostasis to pathogenesis.

Matsusaki M, Kanemura S, Kinoshita M, Lee YH, Inaba K, Okumura M.

Biochim Biophys Acta Gen Subj. 2019 Apr 12. pii: S0304-4165(19)30080-7. doi: 10.1016/j.bbagen.2019.04.003. [Epub ahead of print]


Temperature Dependence Study of the Kinetics and Product Yields of the HO2 + CH3C(O)O2 Reaction by Direct Detection of OH and HO2 Radicals Using 2f-IR Wavelength Modulation Spectroscopy.

Hui AO, Fradet M, Okumura M, Sander SP.

J Phys Chem A. 2019 May 2;123(17):3655-3671. doi: 10.1021/acs.jpca.9b00442. Epub 2019 Apr 17.


Impact of EGFR Mutation and ALK Translocation on Recurrence Pattern After Definitive Chemoradiotherapy for Inoperable Stage III Non-squamous Non-small-cell Lung Cancer.

Nakamura M, Kageyama SI, Niho S, Okumura M, Hojo H, Motegi A, Nakamura N, Zenda S, Yoh K, Goto K, Akimoto T.

Clin Lung Cancer. 2019 May;20(3):e256-e264. doi: 10.1016/j.cllc.2019.02.021. Epub 2019 Mar 4.


Long-Term Outcomes After Surgical Resection for Pleural Dissemination of Thymoma.

Kimura K, Kanzaki R, Kimura T, Kanou T, Ose N, Funaki S, Minami M, Shintani Y, Okumura M.

Ann Surg Oncol. 2019 Jul;26(7):2073-2080. doi: 10.1245/s10434-019-07330-x. Epub 2019 Mar 28.


Seeking equilibrium: The experiences of parents of infants and toddlers who are deaf/hard-of-hearing.

Vukkadala N, Giridhar SBP, Okumura MJ, Chan DK.

J Pediatr Rehabil Med. 2019;12(1):11-20. doi: 10.3233/PRM-170528.


Theoretical and computational investigations of geometrical, electronic and spin structures of the CaMn4 OX (X = 5, 6) cluster in the Kok cycle Si (i = 0-3) of oxygen evolving complex of photosystem II.

Yamaguchi K, Yamanaka S, Isobe H, Shoji M, Miyagawa K, Nakajima T, Kawakami T, Okumura M.

Physiol Plant. 2019 May;166(1):44-59. doi: 10.1111/ppl.12960. Epub 2019 Apr 4.


Linear Response Functions of Densities and Spin Densities for Systematic Modeling of the QM/MM Approach for Mono- and Poly-Nuclear Transition Metal Systems.

Kitakawa CK, Maruyama T, Oonari J, Mitsuta Y, Kawakami T, Okumura M, Yamaguchi K, Yamanaka S.

Molecules. 2019 Feb 25;24(4). pii: E821. doi: 10.3390/molecules24040821.


Long-term outcomes and prognostic factors of pulmonary metastasectomy for osteosarcoma and soft tissue sarcoma.

Yamamoto Y, Kanzaki R, Kanou T, Ose N, Funaki S, Shintani Y, Minami M, Outani H, Takenaka S, Hamada K, Yoshikawa H, Okumura M.

Int J Clin Oncol. 2019 Jul;24(7):863-870. doi: 10.1007/s10147-019-01422-0. Epub 2019 Feb 26.


Peripheral T cell cytotoxicity predicts T cell function in the tumor microenvironment.

Iwahori K, Shintani Y, Funaki S, Yamamoto Y, Matsumoto M, Yoshida T, Morimoto-Okazawa A, Kawashima A, Sato E, Gottschalk S, Okumura M, Kumanogoh A, Wada H.

Sci Rep. 2019 Feb 22;9(1):2636. doi: 10.1038/s41598-019-39345-5.


[Development of Novel Immobilization Adapter for Head and Neck Radiotherapy with Low-attenuation Material].

Matsumoto K, Saika T, Shimomura K, Hanaoka K, Tamura M, Monzen H, Hayakawa M, Okumura M.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2019;75(2):167-173. doi: 10.6009/jjrt.2019_JSRT_75.2.167. Japanese.


Tumour size determines both recurrence-free survival and disease-specific survival after surgical treatment for thymoma.

Okumura M, Yoshino I, Yano M, Watanabe SI, Tsuboi M, Yoshida K, Date H, Yokoi K, Nakajima J, Toyooka SI, Asamura H, Miyaoka E.

Eur J Cardiothorac Surg. 2019 Jul 1;56(1):174-181. doi: 10.1093/ejcts/ezz001.


Development of the ReaxFF Methodology for Electrolyte-Water Systems.

Fedkin MV, Shin YK, Dasgupta N, Yeon J, Zhang W, van Duin D, van Duin ACT, Mori K, Fujiwara A, Machida M, Nakamura H, Okumura M.

J Phys Chem A. 2019 Mar 14;123(10):2125-2141. doi: 10.1021/acs.jpca.8b10453. Epub 2019 Mar 1.


Upfront surgery in patients with clinical skip N2 lung cancer based on results of modern radiological examinations.

Maniwa T, Shintani Y, Okami J, Kadota Y, Takeuchi Y, Takami K, Yokouchi H, Kurokawa E, Kanzaki R, Sakamaki Y, Shiono H, Iwasaki T, Nishioka K, Kodama K, Okumura M; Thoracic Surgery Study Group of Osaka University (TSSGO).

J Thorac Dis. 2018 Dec;10(12):6828-6837. doi: 10.21037/jtd.2018.10.115.


Chest tube management in patients undergoing lobectomy.

Shintani Y, Funaki S, Ose N, Kanou T, Kanzaki R, Minami M, Okumura M.

J Thorac Dis. 2018 Dec;10(12):6432-6435. doi: 10.21037/jtd.2018.11.47. No abstract available.


Extent of Spin Contamination Errors in DFT/Plane-wave Calculation of Surfaces: A Case of Au Atom Aggregation on a MgO Surface.

Tada K, Maruyama T, Koga H, Okumura M, Tanaka S.

Molecules. 2019 Jan 30;24(3). pii: E505. doi: 10.3390/molecules24030505.


Two cases of air leak syndrome after bone marrow transplantation successfully treated by the pleural covering technique.

Kunou H, Kanzaki R, Kawamura T, Kanou T, Ose N, Funaki S, Shintani Y, Minami M, Okumura M.

Gen Thorac Cardiovasc Surg. 2019 Jan 2. doi: 10.1007/s11748-018-01057-4. [Epub ahead of print]


The prognostic impact of programmed cell death 1 and its ligand and the correlation with epithelial-mesenchymal transition in thymic carcinoma.

Funaki S, Shintani Y, Fukui E, Yamamoto Y, Kanzaki R, Ose N, Kanou T, Minami M, Mori E, Okumura M.

Cancer Med. 2019 Jan;8(1):216-226. doi: 10.1002/cam4.1943. Epub 2019 Jan 1.


Transdermal delivery of 40-nm silk fibroin nanoparticles.

Takeuchi I, Shimamura Y, Kakami Y, Kameda T, Hattori K, Miura S, Shirai H, Okumura M, Inagi T, Terada H, Makino K.

Colloids Surf B Biointerfaces. 2019 Mar 1;175:564-568. doi: 10.1016/j.colsurfb.2018.12.012. Epub 2018 Dec 7.


Correction to: Laparoscopic repair of an incarcerated diaphragmatic hernia after right hepatectomy for hepatic injury: a case report.

Takaichi S, Takahashi T, Funaki S, Tanaka K, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Nakajima K, Okumura M, Mori M, Doki Y.

Surg Case Rep. 2018 Dec 21;4(1):147. doi: 10.1186/s40792-018-0551-z.


Semaphorin 7A promotes EGFR-TKI resistance in EGFR mutant lung adenocarcinoma cells.

Kinehara Y, Nagatomo I, Koyama S, Ito D, Nojima S, Kurebayashi R, Nakanishi Y, Suga Y, Nishijima-Futami Y, Osa A, Nakatani T, Kato Y, Nishide M, Hayama Y, Higashiguchi M, Morimura O, Miyake K, Kang S, Minami T, Hirata H, Iwahori K, Takimoto T, Takamatsu H, Takeda Y, Hosen N, Hoshino S, Shintani Y, Okumura M, Kumagai T, Nishino K, Imamura F, Nakatsuka SI, Kijima T, Kida H, Kumanogoh A.

JCI Insight. 2018 Dec 20;3(24). pii: 123093. doi: 10.1172/jci.insight.123093.


Palladium-Catalyzed Dearomative syn-1,4-Diamination.

Wertjes WC, Okumura M, Sarlah D.

J Am Chem Soc. 2019 Jan 9;141(1):163-167. doi: 10.1021/jacs.8b13030. Epub 2018 Dec 21.


Analysis of radiosensitivity of cancer stem-like cells derived from canine cancer cell lines.

Deguchi T, Hosoya K, Murase Y, Koangyong S, Kim S, Okumura M.

Vet Comp Oncol. 2019 Jun;17(2):119-129. doi: 10.1111/vco.12452. Epub 2019 Jan 20.


Anti-arthritic effect of pentosan polysulfate in rats with collagen-induced arthritis.

Suranji Wijekoon HM, Kim S, Bwalya EC, Fang J, Aoshima K, Hosoya K, Okumura M.

Res Vet Sci. 2019 Feb;122:179-185. doi: 10.1016/j.rvsc.2018.11.028. Epub 2018 Dec 1.


Coupling effects of thiol and urea-type groups for promotion of oxidative protein folding.

Okada S, Matsusaki M, Arai K, Hidaka Y, Inaba K, Okumura M, Muraoka T.

Chem Commun (Camb). 2019 Jan 15;55(6):759-762. doi: 10.1039/c8cc08657e.


Two cases of lobectomy for lung cancer after transcatheter aortic valve implantation.

Nagata H, Kanzaki R, Kanou T, Ose N, Funaki S, Shintani Y, Minami M, Mizote I, Sakata Y, Maeda K, Kuratani T, Sawa Y, Okumura M.

Surg Case Rep. 2018 Dec 3;4(1):139. doi: 10.1186/s40792-018-0548-7.


Laparoscopic repair of an incarcerated diaphragmatic hernia after right hepatectomy for hepatic injury: a case report.

Takaichi S, Takahashi T, Funaki S, Tanaka K, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Nakajima K, Okumura M, Mori M, Doki Y.

Surg Case Rep. 2018 Nov 19;4(1):135. doi: 10.1186/s40792-018-0542-0. Erratum in: Surg Case Rep. 2018 Dec 21;4(1):147.


Theoretical study of correlations between the coordination structures and catalytic activities in polymer-stabilized au nanocluster catalysts.

Ato Y, Hayashi A, Koga H, Tada K, Kawakami T, Yamanaka S, Okumura M.

J Comput Chem. 2019 Jan 5;40(1):222-228. doi: 10.1002/jcc.25375. Epub 2018 Nov 19.


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