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Items: 20

1.

An L319F mutation in transmembrane region 3 (TM3) selectively reduces sensitivity to okaramine B of the Bombyx mori l-glutamate-gated chloride channel.

Furutani S, Okuhara D, Hashimoto A, Ihara M, Kai K, Hayashi H, Sattelle DB, Matsuda K.

Biosci Biotechnol Biochem. 2017 Oct;81(10):1861-1867. doi: 10.1080/09168451.2017.1359487. Epub 2017 Aug 21.

PMID:
28825521
2.

Splice Variants of pH-Sensitive Chloride Channel Identify a Key Determinant of Ivermectin Sensitivity in the Larvae of the Silkworm Bombyx mori.

Okuhara D, Furutani S, Ito K, Ihara M, Matsuda K.

Mol Pharmacol. 2017 Oct;92(4):491-499. doi: 10.1124/mol.117.109199. Epub 2017 Jul 24.

PMID:
28739571
3.

Loops D, E and G in the Drosophila Dα1 subunit contribute to high neonicotinoid sensitivity of Dα1-chicken β2 nicotinic acetylcholine receptor.

Ihara M, Hikida M, Matsushita H, Yamanaka K, Kishimoto Y, Kubo K, Watanabe S, Sakamoto M, Matsui K, Yamaguchi A, Okuhara D, Furutani S, Sattelle DB, Matsuda K.

Br J Pharmacol. 2018 Jun;175(11):1999-2012. doi: 10.1111/bph.13914. Epub 2017 Aug 24.

4.

Altered trafficking and stability of polycystins underlie polycystic kidney disease.

Cai Y, Fedeles SV, Dong K, Anyatonwu G, Onoe T, Mitobe M, Gao JD, Okuhara D, Tian X, Gallagher AR, Tang Z, Xie X, Lalioti MD, Lee AH, Ehrlich BE, Somlo S.

J Clin Invest. 2014 Dec;124(12):5129-44. doi: 10.1172/JCI67273. Epub 2014 Nov 3.

5.

Members of the thrombospondin gene family bind stromal interaction molecule 1 and regulate calcium channel activity.

Duquette M, Nadler M, Okuhara D, Thompson J, Shuttleworth T, Lawler J.

Matrix Biol. 2014 Jul;37:15-24. doi: 10.1016/j.matbio.2014.05.004. Epub 2014 May 16.

6.

Characterization of a novel CRAC inhibitor that potently blocks human T cell activation and effector functions.

Chen G, Panicker S, Lau KY, Apparsundaram S, Patel VA, Chen SL, Soto R, Jung JK, Ravindran P, Okuhara D, Bohnert G, Che Q, Rao PE, Allard JD, Badi L, Bitter HM, Nunn PA, Narula SK, DeMartino JA.

Mol Immunol. 2013 Jul;54(3-4):355-67. doi: 10.1016/j.molimm.2012.12.011. Epub 2013 Jan 26.

PMID:
23357789
7.

Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.

Geng L, Boehmerle W, Maeda Y, Okuhara DY, Tian X, Yu Z, Choe CU, Anyatonwu GI, Ehrlich BE, Somlo S.

Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15920-5. doi: 10.1073/pnas.0805062105. Epub 2008 Oct 3.

8.

Diluted isoflurane as a suitable alternative for diethyl ether for rat anaesthesia in regular toxicology studies.

Nagate T, Chino T, Nishiyama C, Okuhara D, Tahara T, Maruyama Y, Kasahara H, Takashima K, Kobayashi S, Motokawa Y, Muto S, Kuroda J.

J Vet Med Sci. 2007 Nov;69(11):1137-43.

9.

Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease.

Leuenroth SJ, Okuhara D, Shotwell JD, Markowitz GS, Yu Z, Somlo S, Crews CM.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4389-94. Epub 2007 Mar 6.

10.

Transient receptor potential channels as drug targets.

Okuhara DY, Hsia AY, Xie M.

Expert Opin Ther Targets. 2007 Mar;11(3):391-401. Review.

PMID:
17298296
11.

Polycystin-2 traffics to cilia independently of polycystin-1 by using an N-terminal RVxP motif.

Geng L, Okuhara D, Yu Z, Tian X, Cai Y, Shibazaki S, Somlo S.

J Cell Sci. 2006 Apr 1;119(Pt 7):1383-95. Epub 2006 Mar 14.

12.

Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812.

Cai Y, Anyatonwu G, Okuhara D, Lee KB, Yu Z, Onoe T, Mei CL, Qian Q, Geng L, Wiztgall R, Ehrlich BE, Somlo S.

J Biol Chem. 2004 May 7;279(19):19987-95. Epub 2004 Jan 22.

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Corticosterone alters G protein alpha-subunit levels in the rat hippocampus.

Okuhara DY, Beck SG, Muma NA.

Brain Res. 1997 Jan 16;745(1-2):144-51.

PMID:
9037403
17.

Differential immunohistochemical labeling of Gs, G(il) and 2, and G(o) alpha-subunits in rat forebrain.

Okuhara DY, Lee JM, Beck SG, Muma NA.

Synapse. 1996 Aug;23(4):246-57.

PMID:
8855509
18.

Corticosterone alters 5-HT1A receptor-mediated hyperpolarization in area CA1 hippocampal pyramidal neurons.

Beck SG, Choi KC, List TJ, Okuhara DY, Birnsteil S.

Neuropsychopharmacology. 1996 Jan;14(1):27-33.

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20.

An efficient method to dialyze small volumes.

Okuhara DY, Macara IG.

Biotechniques. 1991 May;10(5):611. No abstract available.

PMID:
1910777

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