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Items: 1 to 50 of 62

1.

Reduced arterial compliance along the cerebrovascular tree predicts cognitive slowing in multiple sclerosis: Evidence for a neurovascular uncoupling hypothesis.

Sivakolundu DK, West KL, Maruthy GB, Zuppichini M, Turner MP, Abdelkarim D, Zhao Y, Nguyen D, Spence JS, Lu H, Okuda DT, Rypma B.

Mult Scler. 2019 Aug 2:1352458519866605. doi: 10.1177/1352458519866605. [Epub ahead of print]

PMID:
31373536
2.

Three-Dimensional Lesion Phenotyping and Physiologic Characterization Inform Remyelination Ability in Multiple Sclerosis.

Sivakolundu DK, Hansen MR, West KL, Wang Y, Stanley T, Wilson A, McCreary M, Turner MP, Pinho MC, Newton BD, Guo X, Rypma B, Okuda DT.

J Neuroimaging. 2019 Sep;29(5):605-614. doi: 10.1111/jon.12633. Epub 2019 May 30.

PMID:
31148298
3.

α4-integrin deficiency in B cells does not affect disease in a T-cell-mediated EAE disease model.

Hussain RZ, Cravens PD, Miller-Little WA, Doelger R, Granados V, Herndon E, Okuda DT, Eagar TN, Stüve O.

Neurol Neuroimmunol Neuroinflamm. 2019 Apr 16;6(4):e563. doi: 10.1212/NXI.0000000000000563. eCollection 2019 Jul. Erratum in: Neurol Neuroimmunol Neuroinflamm. 2019 Jul 05;6(4):e585.

4.

Oligoclonal bands increase the specificity of MRI criteria to predict multiple sclerosis in children with radiologically isolated syndrome.

Makhani N, Lebrun C, Siva A, Narula S, Wassmer E, Brassat D, Brenton JN, Cabre P, Carra Dallière C, de Seze J, Durand Dubief F, Inglese M, Langille M, Mathey G, Neuteboom RF, Pelletier J, Pohl D, Reich DS, Ignacio Rojas J, Shabanova V, Shapiro ED, Stone RT, Tenembaum S, Tintoré M, Uygunoglu U, Vargas W, Venkateswaren S, Vermersch P, Kantarci O, Okuda DT, Pelletier D; Observatoire Francophone de la Sclérose en Plaques (OFSEP), Société Francophone de la Sclérose en Plaques (SFSEP), the Radiologically Isolated Syndrome Consortium (RISC) and the Pediatric Radiologically Isolated Syndrome Consortium (PARIS).

Mult Scler J Exp Transl Clin. 2019 Mar 20;5(1):2055217319836664. doi: 10.1177/2055217319836664. eCollection 2019 Jan-Mar.

5.

TLR3 agonism re-establishes CNS immune competence during α4-integrin deficiency.

Hussain RZ, Cravens PC, Doelger R, Dentel B, Herndon E, Loof N, Tsai P, Okuda DT, Racke MK, Stüve O.

Ann Clin Transl Neurol. 2018 Oct 30;5(12):1543-1561. doi: 10.1002/acn3.664. eCollection 2018 Dec.

6.

Body mass index, but not vitamin D status, is associated with brain volume change in MS.

Mowry EM, Azevedo CJ, McCulloch CE, Okuda DT, Lincoln RR, Waubant E, Hauser SL, Pelletier D.

Neurology. 2018 Dec 11;91(24):e2256-e2264. doi: 10.1212/WNL.0000000000006644. Epub 2018 Nov 14.

PMID:
30429274
7.

Leveraging technology to identify subclinical deficits in radiologically isolated syndrome.

Okuda DT.

Eur J Neurol. 2019 Jan;26(1):3-4. doi: 10.1111/ene.13810. Epub 2018 Oct 20. No abstract available.

PMID:
30221805
8.

Post-gadolinium 3-dimensional spatial, surface, and structural characteristics of glioblastomas differentiate pseudoprogression from true tumor progression.

Hansen MR, Pan E, Wilson A, McCreary M, Wang Y, Stanley T, Pinho MC, Guo X, Okuda DT.

J Neurooncol. 2018 Sep;139(3):731-738. doi: 10.1007/s11060-018-2920-7. Epub 2018 Jun 7.

PMID:
29882044
9.

Precision medicine for multiple sclerosis promotes preventative medicine.

Hansen MR, Okuda DT.

Ann N Y Acad Sci. 2018 May;1420(1):62-71. doi: 10.1111/nyas.13846.

PMID:
29878402
10.

Preserved canonicality of the BOLD hemodynamic response reflects healthy cognition: Insights into the healthy brain through the window of Multiple Sclerosis.

Turner MP, Hubbard NA, Sivakolundu DK, Himes LM, Hutchison JL, Hart J Jr, Spence JS, Frohman EM, Frohman TC, Okuda DT, Rypma B.

Neuroimage. 2019 Apr 15;190:46-55. doi: 10.1016/j.neuroimage.2017.12.081. Epub 2018 Feb 15. Review.

PMID:
29454932
11.

Cervical spinal cord atrophy: An early marker of progressive MS onset.

Zeydan B, Gu X, Atkinson EJ, Keegan BM, Weinshenker BG, Tillema JM, Pelletier D, Azevedo CJ, Lebrun-Frenay C, Siva A, Okuda DT, Kantarci K, Kantarci OH.

Neurol Neuroimmunol Neuroinflamm. 2018 Jan 22;5(2):e435. doi: 10.1212/NXI.0000000000000435. eCollection 2018 Mar.

12.

Contemporary Topics in Multiple Sclerosis.

Okuda DT.

Neurol Clin. 2018 Feb;36(1):xiii-xiv. doi: 10.1016/j.ncl.2017.10.001. No abstract available.

PMID:
29157406
13.

Anomalies Characteristic of Central Nervous System Demyelination: Radiologically Isolated Syndrome.

Lebrun C, Kantarci OH, Siva A, Pelletier D, Okuda DT; RISConsortium.

Neurol Clin. 2018 Feb;36(1):59-68. doi: 10.1016/j.ncl.2017.08.004. Review.

PMID:
29157404
14.

Multiple Sclerosis in the Contemporary Age: Understanding the Millennial Patient with Multiple Sclerosis to Create Next-Generation Care.

Hansen MR, Okuda DT.

Neurol Clin. 2018 Feb;36(1):219-230. doi: 10.1016/j.ncl.2017.08.012. Review.

PMID:
29157401
15.

Patient outcomes influenced by reduced lymphocyte counts after dimethyl fumarate initiation.

Wright K, Winkler MD, Newton BD, Sormani MP, Okuda DT.

Neurol Neuroimmunol Neuroinflamm. 2017 Sep 25;4(6):e397. doi: 10.1212/NXI.0000000000000397. eCollection 2017 Nov.

16.

Radiologically isolated syndrome in children: Clinical and radiologic outcomes.

Makhani N, Lebrun C, Siva A, Brassat D, Carra Dallière C, de Seze J, Du W, Durand Dubief F, Kantarci O, Langille M, Narula S, Pelletier J, Rojas JI, Shapiro ED, Stone RT, Tintoré M, Uygunoglu U, Vermersch P, Wassmer E, Okuda DT, Pelletier D.

Neurol Neuroimmunol Neuroinflamm. 2017 Sep 25;4(6):e395. doi: 10.1212/NXI.0000000000000395. eCollection 2017 Nov.

17.

Radiologically isolated syndrome should be treated with disease-modifying therapy - Yes.

Okuda DT.

Mult Scler. 2017 Dec;23(14):1818-1819. doi: 10.1177/1352458517729462. Epub 2017 Sep 14. No abstract available.

PMID:
28906165
18.

Calibrated imaging reveals altered grey matter metabolism related to white matter microstructure and symptom severity in multiple sclerosis.

Hubbard NA, Turner MP, Ouyang M, Himes L, Thomas BP, Hutchison JL, Faghihahmadabadi S, Davis SL, Strain JF, Spence J, Krawczyk DC, Huang H, Lu H, Hart J Jr, Frohman TC, Frohman EM, Okuda DT, Rypma B.

Hum Brain Mapp. 2017 Nov;38(11):5375-5390. doi: 10.1002/hbm.23727. Epub 2017 Aug 16.

19.

Evaluation of Visual-Evoked Cerebral Metabolic Rate of Oxygen as a Diagnostic Marker in Multiple Sclerosis.

Hubbard NA, Sanchez Araujo Y, Caballero C, Ouyang M, Turner MP, Himes L, Faghihahmadabadi S, Thomas BP, Hart J, Huang H, Okuda DT, Rypma B.

Brain Sci. 2017 Jun 11;7(6). pii: E64. doi: 10.3390/brainsci7060064.

20.

Three-Dimensional Shape and Surface Features Distinguish Multiple Sclerosis Lesions from Nonspecific White Matter Disease.

Newton BD, Wright K, Winkler MD, Bovis F, Takahashi M, Dimitrov IE, Sormani MP, Pinho MC, Okuda DT.

J Neuroimaging. 2017 Nov;27(6):613-619. doi: 10.1111/jon.12449. Epub 2017 May 10.

PMID:
28488804
21.

Radiologically Isolated Syndrome: MR Imaging Features Suggestive of Multiple Sclerosis Prior to First Symptom Onset.

Okuda DT.

Neuroimaging Clin N Am. 2017 May;27(2):267-275. doi: 10.1016/j.nic.2016.12.008. Epub 2017 Feb 1. Review.

PMID:
28391785
22.

Finger tapping impairments are highly sensitive for evaluating upper motor neuron lesions.

Shirani A, Newton BD, Okuda DT.

BMC Neurol. 2017 Mar 21;17(1):55. doi: 10.1186/s12883-017-0829-y.

23.

Are miRNAs Appropriate Biomarkers for Radiologic Measures of Tissue Injury in Multiple Sclerosis?

Okuda DT.

JAMA Neurol. 2017 Mar 1;74(3):260-261. doi: 10.1001/jamaneurol.2016.5384. No abstract available.

PMID:
28114651
24.

Long-term evolution of multiple sclerosis disability in the treatment era.

University of California, San Francisco MS-EPIC Team:, Cree BA, Gourraud PA, Oksenberg JR, Bevan C, Crabtree-Hartman E, Gelfand JM, Goodin DS, Graves J, Green AJ, Mowry E, Okuda DT, Pelletier D, von Büdingen HC, Zamvil SS, Agrawal A, Caillier S, Ciocca C, Gomez R, Kanner R, Lincoln R, Lizee A, Qualley P, Santaniello A, Suleiman L, Bucci M, Panara V, Papinutto N, Stern WA, Zhu AH, Cutter GR, Baranzini S, Henry RG, Hauser SL.

Ann Neurol. 2016 Oct;80(4):499-510. doi: 10.1002/ana.24747. Epub 2016 Aug 13.

25.

Incidental Lesions Suggesting Multiple Sclerosis.

Okuda DT.

Continuum (Minneap Minn). 2016 Jun;22(3):730-43. doi: 10.1212/CON.0000000000000339. Review.

PMID:
27261679
26.

Therapeutic Advances and Future Prospects in Progressive Forms of Multiple Sclerosis.

Shirani A, Okuda DT, Stüve O.

Neurotherapeutics. 2016 Jan;13(1):58-69. doi: 10.1007/s13311-015-0409-z. Review.

27.

Primary Progressive Multiple Sclerosis Evolving From Radiologically Isolated Syndrome.

Kantarci OH, Lebrun C, Siva A, Keegan MB, Azevedo CJ, Inglese M, Tintoré M, Newton BD, Durand-Dubief F, Amato MP, De Stefano N, Sormani MP, Pelletier D, Okuda DT.

Ann Neurol. 2016 Feb;79(2):288-94. doi: 10.1002/ana.24564. Epub 2015 Dec 29.

PMID:
26599831
28.

Aquatic training in MS: neurotherapeutic impact upon quality of life.

Frohman AN, Okuda DT, Beh S, Treadaway K, Mooi C, Davis SL, Shah A, Frohman TC, Frohman EM.

Ann Clin Transl Neurol. 2015 Aug;2(8):864-72. doi: 10.1002/acn3.220. Epub 2015 Jun 26.

29.

Early CNS neurodegeneration in radiologically isolated syndrome.

Azevedo CJ, Overton E, Khadka S, Buckley J, Liu S, Sampat M, Kantarci O, Lebrun Frenay C, Siva A, Okuda DT, Pelletier D.

Neurol Neuroimmunol Neuroinflamm. 2015 Apr 9;2(3):e102. doi: 10.1212/NXI.0000000000000102. eCollection 2015 Jun.

30.

Pontine myelinolysis following excessive consumption of commercial energy drinks.

Newton BD, Okuda DT.

Neurol Neuroimmunol Neuroinflamm. 2015 Mar 12;2(3):e91. doi: 10.1212/NXI.0000000000000091. eCollection 2015 Jun. No abstract available.

31.

Thoracic spinal cord lesions are influenced by the degree of cervical spine involvement in multiple sclerosis.

Hua LH, Donlon SL, Sobhanian MJ, Portner SM, Okuda DT.

Spinal Cord. 2015 Jul;53(7):520-5. doi: 10.1038/sc.2014.238. Epub 2015 Jan 13.

PMID:
25582716
32.

Central neuropathic pain in MS is due to distinct thoracic spinal cord lesions.

Okuda DT, Melmed K, Matsuwaki T, Blomqvist A, Craig AD.

Ann Clin Transl Neurol. 2014 Aug;1(8):554-61. doi: 10.1002/acn3.85. Epub 2014 Jul 28.

33.

In vivo evidence of glutamate toxicity in multiple sclerosis.

Azevedo CJ, Kornak J, Chu P, Sampat M, Okuda DT, Cree BA, Nelson SJ, Hauser SL, Pelletier D.

Ann Neurol. 2014 Aug;76(2):269-78. doi: 10.1002/ana.24202. Epub 2014 Jul 9.

34.

Radiologically isolated syndrome: 5-year risk for an initial clinical event.

Okuda DT, Siva A, Kantarci O, Inglese M, Katz I, Tutuncu M, Keegan BM, Donlon S, Hua le H, Vidal-Jordana A, Montalban X, Rovira A, Tintoré M, Amato MP, Brochet B, de Seze J, Brassat D, Vermersch P, De Stefano N, Sormani MP, Pelletier D, Lebrun C; Radiologically Isolated Syndrome Consortium (RISC); Club Francophone de la Sclérose en Plaques (CFSEP).

PLoS One. 2014 Mar 5;9(3):e90509. doi: 10.1371/journal.pone.0090509. eCollection 2014.

35.

Immunosuppressive treatments in multiple sclerosis.

Okuda DT.

Handb Clin Neurol. 2014;122:503-11. doi: 10.1016/B978-0-444-52001-2.00022-4. Review.

PMID:
24507533
36.

A case of Susac syndrome with cervical spinal cord involvement on MRI.

Hua le H, Donlon SL, Okuda DT.

J Neurol Sci. 2014 Feb 15;337(1-2):228-31. doi: 10.1016/j.jns.2013.11.040. Epub 2013 Dec 3.

PMID:
24365248
37.

Metabolite changes in radiologically isolated syndrome: more pathology than meets the eye?

Okuda DT, Vrenken H.

Neurology. 2013 Jun 4;80(23):2084-5. doi: 10.1212/WNL.0b013e318295d7b2. Epub 2013 May 1. No abstract available.

PMID:
23635959
38.

Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosis.

Mowry EM, Waubant E, McCulloch CE, Okuda DT, Evangelista AA, Lincoln RR, Gourraud PA, Brenneman D, Owen MC, Qualley P, Bucci M, Hauser SL, Pelletier D.

Ann Neurol. 2012 Aug;72(2):234-40. doi: 10.1002/ana.23591.

39.

From injection therapies to natalizumab: views on the treatment of multiple sclerosis.

Bomprezzi R, Okuda DT, Alderazi YJ, Stüve O, Frohman EM.

Ther Adv Neurol Disord. 2012 Mar;5(2):97-104. doi: 10.1177/1756285611431289.

40.

Impact of pregnancy on conversion to clinically isolated syndrome in a radiologically isolated syndrome cohort.

Lebrun C, Le Page E, Kantarci O, Siva A, Pelletier D, Okuda DT; Club Francophone de Sclerose en Plaques (CFSEP); Radiologically Isolated Syndrome Consortium (RISC) Group.

Mult Scler. 2012 Sep;18(9):1297-302. Epub 2012 Feb 2.

PMID:
22300971
41.

Switching multiple sclerosis patients with breakthrough disease to second-line therapy.

Castillo-Trivino T, Mowry EM, Gajofatto A, Chabas D, Crabtree-Hartman E, Cree BA, Goodin DS, Green AJ, Okuda DT, Pelletier D, Zamvil SS, Vittinghoff E, Waubant E.

PLoS One. 2011 Feb 3;6(2):e16664. doi: 10.1371/journal.pone.0016664.

42.

Asymptomatic spinal cord lesions predict disease progression in radiologically isolated syndrome.

Okuda DT, Mowry EM, Cree BA, Crabtree EC, Goodin DS, Waubant E, Pelletier D.

Neurology. 2011 Feb 22;76(8):686-92. doi: 10.1212/WNL.0b013e31820d8b1d. Epub 2011 Jan 26.

43.

Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis.

Baranzini SE, Srinivasan R, Khankhanian P, Okuda DT, Nelson SJ, Matthews PM, Hauser SL, Oksenberg JR, Pelletier D.

Brain. 2010 Sep;133(9):2603-11. doi: 10.1093/brain/awq192.

44.

Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome.

Moore F, Okuda DT.

Neurology. 2009 Nov 17;73(20):1714. doi: 10.1212/WNL.0b013e3181bd69a9. No abstract available.

PMID:
19918002
45.

Unanticipated demyelinating pathology of the CNS.

Okuda DT.

Nat Rev Neurol. 2009 Nov;5(11):591-7. doi: 10.1038/nrneurol.2009.157. Epub 2009 Oct 6. Review.

PMID:
19806149
46.

Difference in disease burden and activity in pediatric patients on brain magnetic resonance imaging at time of multiple sclerosis onset vs adults.

Waubant E, Chabas D, Okuda DT, Glenn O, Mowry E, Henry RG, Strober JB, Soares B, Wintermark M, Pelletier D.

Arch Neurol. 2009 Aug;66(8):967-71. doi: 10.1001/archneurol.2009.135.

PMID:
19667217
47.

Quality of life in multiple sclerosis is associated with lesion burden and brain volume measures.

Mowry EM, Beheshtian A, Waubant E, Goodin DS, Cree BA, Qualley P, Lincoln R, George MF, Gomez R, Hauser SL, Okuda DT, Pelletier D.

Neurology. 2009 May 19;72(20):1760-5. doi: 10.1212/WNL.0b013e3181a609f8.

48.

Connecting white matter injury and thalamic atrophy in clinically isolated syndromes.

Henry RG, Shieh M, Amirbekian B, Chung S, Okuda DT, Pelletier D.

J Neurol Sci. 2009 Jul 15;282(1-2):61-6. doi: 10.1016/j.jns.2009.02.379. Epub 2009 Apr 23.

PMID:
19394969
49.

High-resolution phased-array MRI of the human brain at 7 tesla: initial experience in multiple sclerosis patients.

Metcalf M, Xu D, Okuda DT, Carvajal L, Srinivasan R, Kelley DA, Mukherjee P, Nelson SJ, Vigneron DB, Pelletier D.

J Neuroimaging. 2010 Apr;20(2):141-7. doi: 10.1111/j.1552-6569.2008.00338.x. Epub 2009 Jan 29.

50.

Recurrent asymptomatic demyelinating disease following 13-cis-retinoic acid exposure.

Okuda DT, Prados MD.

BMJ Case Rep. 2009;2009. pii: bcr05.2009.1908. doi: 10.1136/bcr.05.2009.1908. Epub 2009 Sep 8.

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