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Items: 36


The emerging roles of macrophages in cancer metastasis and response to chemotherapy.

Sanchez LR, Borriello L, Entenberg D, Condeelis JS, Oktay MH, Karagiannis GS.

J Leukoc Biol. 2019 Feb 5. doi: 10.1002/JLB.MR0218-056RR. [Epub ahead of print] Review.


Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth.

Mao SPH, Park M, Cabrera RM, Christin JR, Karagiannis GS, Oktay MH, Zaiss DMW, Abrams SI, Guo W, Condeelis JS, Kenny PA, Segall JE.

Breast Cancer Res. 2018 Oct 26;20(1):131. doi: 10.1186/s13058-018-1057-0.


Black race and distant recurrence after neoadjuvant or adjuvant chemotherapy in breast cancer.

Pastoriza JM, Karagiannis GS, Lin J, Lanjewar S, Entenberg D, Condeelis JS, Sparano JA, Xue X, Rohan TE, Oktay MH.

Clin Exp Metastasis. 2018 Oct;35(7):613-623. doi: 10.1007/s10585-018-9932-8. Epub 2018 Aug 22.


Chemotherapy-induced metastasis in breast cancer.

Karagiannis GS, Condeelis JS, Oktay MH.

Oncotarget. 2017 Nov 27;8(67):110733-110734. doi: 10.18632/oncotarget.22717. eCollection 2017 Dec 19. No abstract available.


Chemotherapy-induced metastasis: mechanisms and translational opportunities.

Karagiannis GS, Condeelis JS, Oktay MH.

Clin Exp Metastasis. 2018 Apr;35(4):269-284. doi: 10.1007/s10585-017-9870-x. Epub 2018 Jan 6. Review.


A metastasis biomarker (MetaSite Breast™ Score) is associated with distant recurrence in hormone receptor-positive, HER2-negative early-stage breast cancer.

Sparano JA, Gray R, Oktay MH, Entenberg D, Rohan T, Xue X, Donovan M, Peterson M, Shuber A, Hamilton DA, D'Alfonso T, Goldstein LJ, Gertler F, Davidson NE, Condeelis J, Jones J.

NPJ Breast Cancer. 2017 Nov 8;3:42. doi: 10.1038/s41523-017-0043-5. eCollection 2017.


Time-lapsed, large-volume, high-resolution intravital imaging for tissue-wide analysis of single cell dynamics.

Entenberg D, Pastoriza JM, Oktay MH, Voiculescu S, Wang Y, Sosa MS, Aguirre-Ghiso J, Condeelis J.

Methods. 2017 Sep 1;128:65-77. doi: 10.1016/j.ymeth.2017.07.019.


The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors.

Harney AS, Karagiannis GS, Pignatelli J, Smith BD, Kadioglu E, Wise SC, Hood MM, Kaufman MD, Leary CB, Lu WP, Al-Ani G, Chen X, Entenberg D, Oktay MH, Wang Y, Chun L, De Palma M, Jones JG, Flynn DL, Condeelis JS.

Mol Cancer Ther. 2017 Nov;16(11):2486-2501. doi: 10.1158/1535-7163.MCT-17-0241. Epub 2017 Aug 24.


Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism.

Karagiannis GS, Pastoriza JM, Wang Y, Harney AS, Entenberg D, Pignatelli J, Sharma VP, Xue EA, Cheng E, D'Alfonso TM, Jones JG, Anampa J, Rohan TE, Sparano JA, Condeelis JS, Oktay MH.

Sci Transl Med. 2017 Jul 5;9(397). pii: eaan0026. doi: 10.1126/scitranslmed.aan0026. Erratum in: Sci Transl Med. 2017 Jul 19;9(399):.


Lineage-Biased Stem Cells Maintain Estrogen-Receptor-Positive and -Negative Mouse Mammary Luminal Lineages.

Wang C, Christin JR, Oktay MH, Guo W.

Cell Rep. 2017 Mar 21;18(12):2825-2835. doi: 10.1016/j.celrep.2017.02.071.


Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/MenaINV-initiated invadopodium formation.

Pignatelli J, Bravo-Cordero JJ, Roh-Johnson M, Gandhi SJ, Wang Y, Chen X, Eddy RJ, Xue A, Singer RH, Hodgson L, Oktay MH, Condeelis JS.

Sci Rep. 2016 Nov 30;6:37874. doi: 10.1038/srep37874.


Mammary-Stem-Cell-Based Somatic Mouse Models Reveal Breast Cancer Drivers Causing Cell Fate Dysregulation.

Zhang Z, Christin JR, Wang C, Ge K, Oktay MH, Guo W.

Cell Rep. 2016 Sep 20;16(12):3146-3156. doi: 10.1016/j.celrep.2016.08.048.


Signatures of breast cancer metastasis at a glance.

Karagiannis GS, Goswami S, Jones JG, Oktay MH, Condeelis JS.

J Cell Sci. 2016 May 1;129(9):1751-8. doi: 10.1242/jcs.183129. Epub 2016 Apr 15. Review.


The Application of Molecular Diagnostics to Stained Cytology Smears.

Oktay MH, Adler E, Hakima L, Grunblatt E, Pieri E, Seymour A, Khader S, Cajigas A, Suhrland M, Goswami S.

J Mol Diagn. 2016 May;18(3):407-415. doi: 10.1016/j.jmoldx.2016.01.007. Epub 2016 Feb 24.


Cell-to-cell communication in cancer: workshop report.

Oktay MH, Lee YF, Harney A, Farrell D, Kuhn NZ, Morris SA, Greenspan E, Mohla S, Grodzinski P, Norton L.

NPJ Breast Cancer. 2015 Nov 25;1:15022. doi: 10.1038/npjbcancer.2015.22. eCollection 2015.


Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA.

Harney AS, Arwert EN, Entenberg D, Wang Y, Guo P, Qian BZ, Oktay MH, Pollard JW, Jones JG, Condeelis JS.

Cancer Discov. 2015 Sep;5(9):932-43. doi: 10.1158/2159-8290.CD-15-0012. Epub 2015 Aug 12.


TMEM: a novel breast cancer dissemination marker for the assessment of metastatic risk.

Oktay MH, Jones JG.

Biomark Med. 2015;9(2):81-4. doi: 10.2217/bmm.14.104. No abstract available.


Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration.

Pignatelli J, Goswami S, Jones JG, Rohan TE, Pieri E, Chen X, Adler E, Cox D, Maleki S, Bresnick A, Gertler FB, Condeelis JS, Oktay MH.

Sci Signal. 2014 Nov 25;7(353):ra112. doi: 10.1126/scisignal.2005329.


Tumor microenvironment of metastasis and risk of distant metastasis of breast cancer.

Rohan TE, Xue X, Lin HM, D'Alfonso TM, Ginter PS, Oktay MH, Robinson BD, Ginsberg M, Gertler FB, Glass AG, Sparano JA, Condeelis JS, Jones JG.

J Natl Cancer Inst. 2014 Jun 3;106(8). pii: dju136. doi: 10.1093/jnci/dju136. Print 2014 Aug.


Septin 9 amplification and isoform-specific expression in peritumoral and tumor breast tissue.

Connolly D, Hoang HG, Adler E, Tazearslan C, Simmons N, Bernard VV, Castaldi M, Oktay MH, Montagna C.

Biol Chem. 2014 Feb;395(2):157-67. doi: 10.1515/hsz-2013-0247.


Estrogen, progesterone, and HER-2 receptor immunostaining in cytology: the effect of varied fixation on human breast cancer cells.

Maleki S, Dorokhova O, Sunkara J, Schlesinger K, Suhrland M, Oktay MH.

Diagn Cytopathol. 2013 Oct;41(10):864-70. doi: 10.1002/dc.22973. Epub 2013 Feb 28.


Molecular pathology as the driving force for personalized oncology.

Oktay MH, Hui P.

Expert Rev Mol Diagn. 2012 Nov;12(8):811-3. doi: 10.1586/erm.12.121.


Correlated immunohistochemical and cytological assays for the prediction of hematogenous dissemination of breast cancer.

Oktay MH, Gertler FB, Liu YF, Rohan TE, Condeelis JS, Jones JG.

J Histochem Cytochem. 2012 Mar;60(3):168-73. doi: 10.1369/0022155411435153. Epub 2012 Jan 3. Review.


Predictors of disease progression in ductal carcinoma in situ of the breast and vascular patterns.

Adler EH, Sunkara JL, Patchefsky AS, Koss LG, Oktay MH.

Hum Pathol. 2012 Apr;43(4):550-6. doi: 10.1016/j.humpath.2011.06.004. Epub 2011 Sep 16.


An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype.

Shapiro IM, Cheng AW, Flytzanis NC, Balsamo M, Condeelis JS, Oktay MH, Burge CB, Gertler FB.

PLoS Genet. 2011 Aug;7(8):e1002218. doi: 10.1371/journal.pgen.1002218. Epub 2011 Aug 18.


Septin 9 isoform expression, localization and epigenetic changes during human and mouse breast cancer progression.

Connolly D, Yang Z, Castaldi M, Simmons N, Oktay MH, Coniglio S, Fazzari MJ, Verdier-Pinard P, Montagna C.

Breast Cancer Res. 2011 Aug 10;13(4):R76. doi: 10.1186/bcr2924.


Mena invasive (Mena(INV)) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM.

Roussos ET, Goswami S, Balsamo M, Wang Y, Stobezki R, Adler E, Robinson BD, Jones JG, Gertler FB, Condeelis JS, Oktay MH.

Clin Exp Metastasis. 2011 Aug;28(6):515-27. doi: 10.1007/s10585-011-9388-6. Epub 2011 Apr 12.


Fine needle aspiration of follicular dendritic cell sarcoma in an HIV-positive man: a case report.

Kure K, Khader SN, Suhrland MJ, Ratech H, Grossberg R, Oktay MH.

Acta Cytol. 2010 Sep-Oct;54(5):707-11.


Prognostic and predictive value of 16p12.1 and 16q22.1 copy number changes in human breast cancer.

Downing TE, Oktay MH, Fazzari MJ, Montagna C.

Cancer Genet Cytogenet. 2010 Apr 1;198(1):52-61. doi: 10.1016/j.cancergencyto.2009.12.007.


Discrepant cytologic and radiographic findings in adjacent galactocele and fibroadenoma: a case report.

Vuolo M, Suhrland MJ, Madan R, Oktay MH.

Acta Cytol. 2009 Mar-Apr;53(2):211-4.


Mechanisms of progression of ductal carcinoma in situ of the breast to invasive cancer. A hypothesis.

Cocker R, Oktay MH, Sunkara JL, Koss LG.

Med Hypotheses. 2007;69(1):57-63. Epub 2007 Jan 25.


Focal adhesion proteins as markers of malignant transformation and prognostic indicators in breast carcinoma.

Madan R, Smolkin MB, Cocker R, Fayyad R, Oktay MH.

Hum Pathol. 2006 Jan;37(1):9-15.


Focal adhesion kinase as a marker of malignant phenotype in breast and cervical carcinomas.

Oktay MH, Oktay K, Hamele-Bena D, Buyuk A, Koss LG.

Hum Pathol. 2003 Mar;34(3):240-5.


Assays for kinase activity.

Oktay MH, Mariotti A, Giancotti FG.

Methods Mol Biol. 1999;129:51-61. No abstract available.


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