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Items: 44

1.

Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity.

Habib AM, Okorokov AL, Hill MN, Bras JT, Lee MC, Li S, Gossage SJ, van Drimmelen M, Morena M, Houlden H, Ramirez JD, Bennett DLH, Srivastava D, Cox JJ.

Br J Anaesth. 2019 Aug;123(2):e249-e253. doi: 10.1016/j.bja.2019.02.019. Epub 2019 Mar 28.

2.

A novel human pain insensitivity disorder caused by a point mutation in ZFHX2.

Habib AM, Matsuyama A, Okorokov AL, Santana-Varela S, Bras JT, Aloisi AM, Emery EC, Bogdanov YD, Follenfant M, Gossage SJ, Gras M, Humphrey J, Kolesnikov A, Le Cann K, Li S, Minett MS, Pereira V, Ponsolles C, Sikandar S, Torres JM, Yamaoka K, Zhao J, Komine Y, Yamamori T, Maniatis N, Panov KI, Houlden H, Ramirez JD, Bennett DLH, Marsili L, Bachiocco V, Wood JN, Cox JJ.

Brain. 2018 Feb 1;141(2):365-376. doi: 10.1093/brain/awx326.

3.

p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress.

Tudzarova S, Mulholland P, Dey A, Stoeber K, Okorokov AL, Williams GH.

Cell Cycle. 2016 Nov;15(21):2958-2972. Epub 2016 Sep 9.

4.

Two p53 tetramers bind one consensus DNA response element.

Kearns S, Lurz R, Orlova EV, Okorokov AL.

Nucleic Acids Res. 2016 Jul 27;44(13):6185-99. doi: 10.1093/nar/gkw215. Epub 2016 Mar 31.

5.

Discovery of Novel Isatin-Based p53 Inducers.

Davidovich P, Aksenova V, Petrova V, Tentler D, Orlova D, Smirnov S, Gurzhiy V, Okorokov AL, Garabadzhiu A, Melino G, Barlev N, Tribulovich V.

ACS Med Chem Lett. 2015 Jul 6;6(8):856-60. doi: 10.1021/acsmedchemlett.5b00011. eCollection 2015 Aug 13.

6.

Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia.

Koenig J, Werdehausen R, Linley JE, Habib AM, Vernon J, Lolignier S, Eijkelkamp N, Zhao J, Okorokov AL, Woods CG, Wood JN, Cox JJ.

PLoS One. 2015 Jun 2;10(6):e0128830. doi: 10.1371/journal.pone.0128830. eCollection 2015.

7.

The physical interaction of Mcm10 with Cdc45 modulates their DNA-binding properties.

Di Perna R, Aria V, De Falco M, Sannino V, Okorokov AL, Pisani FM, De Felice M.

Biochem J. 2013 Sep 1;454(2):333-43. doi: 10.1042/BJ20130059.

PMID:
23750504
8.

Human SIRT1 regulates DNA binding and stability of the Mcm10 DNA replication factor via deacetylation.

Fatoba ST, Tognetti S, Berto M, Leo E, Mulvey CM, Godovac-Zimmermann J, Pommier Y, Okorokov AL.

Nucleic Acids Res. 2013 Apr;41(7):4065-79. doi: 10.1093/nar/gkt131. Epub 2013 Feb 28.

9.

Quaternary structure of the specific p53-DNA complex reveals the mechanism of p53 mutant dominance.

Aramayo R, Sherman MB, Brownless K, Lurz R, Okorokov AL, Orlova EV.

Nucleic Acids Res. 2011 Nov 1;39(20):8960-71. doi: 10.1093/nar/gkr386. Epub 2011 Jul 14.

10.

Human SIRT1 associates with mitotic chromatin and contributes to chromosomal condensation.

Fatoba ST, Okorokov AL.

Cell Cycle. 2011 Jul 15;10(14):2317-22. Epub 2011 Jul 15.

PMID:
21636977
11.

Structure of the hDmc1-ssDNA filament reveals the principles of its architecture.

Okorokov AL, Chaban YL, Bugreev DV, Hodgkinson J, Mazin AV, Orlova EV.

PLoS One. 2010 Jan 6;5(1):e8586. doi: 10.1371/journal.pone.0008586.

12.

The microRNA and p53 families join forces against cancer.

Barlev NA, Sayan BS, Candi E, Okorokov AL.

Cell Death Differ. 2010 Feb;17(2):373-5. doi: 10.1038/cdd.2009.73. No abstract available.

13.

Structural biology of the p53 tumour suppressor.

Okorokov AL, Orlova EV.

Curr Opin Struct Biol. 2009 Apr;19(2):197-202. doi: 10.1016/j.sbi.2009.02.003. Epub 2009 Mar 13. Review.

PMID:
19286366
14.

Hexameric ring structure of human MCM10 DNA replication factor.

Okorokov AL, Waugh A, Hodgkinson J, Murthy A, Hong HK, Leo E, Sherman MB, Stoeber K, Orlova EV, Williams GH.

EMBO Rep. 2007 Oct;8(10):925-30. Epub 2007 Sep 7.

15.

The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity.

Okorokov AL, Sherman MB, Plisson C, Grinkevich V, Sigmundsson K, Selivanova G, Milner J, Orlova EV.

EMBO J. 2006 Nov 1;25(21):5191-200. Epub 2006 Oct 19.

16.

Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A.

Bochkareva E, Kaustov L, Ayed A, Yi GS, Lu Y, Pineda-Lucena A, Liao JC, Okorokov AL, Milner J, Arrowsmith CH, Bochkarev A.

Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15412-7. Epub 2005 Oct 17.

17.

Molecular structure of human geminin.

Okorokov AL, Orlova EV, Kingsbury SR, Bagneris C, Gohlke U, Williams GH, Stoeber K.

Nat Struct Mol Biol. 2004 Oct;11(10):1021-2. Epub 2004 Sep 19.

PMID:
15378034
18.

p53 in a crosstalk between DNA repair and cell cycle checkpoints.

Okorokov AL.

Cell Cycle. 2003 May-Jun;2(3):233-5. Review. No abstract available.

PMID:
12734432
19.

The structure of substrate-free microbial ribonuclease binase and of its complexes with 3'GMP and sulfate ions.

Polyakov KM, Lebedev AA, Okorokov AL, Panov KI, Schulga AA, Pavlovsky AG, Karpeisky MY, Dodson GG.

Acta Crystallogr D Biol Crystallogr. 2002 May;58(Pt 5):744-50. Epub 2002 Apr 26.

PMID:
11976484
20.
21.

DNA damage is able to induce senescence in tumor cells in vitro and in vivo.

te Poele RH, Okorokov AL, Jardine L, Cummings J, Joel SP.

Cancer Res. 2002 Mar 15;62(6):1876-83.

22.

The interaction of p53 with the nuclear matrix is mediated by F-actin and modulated by DNA damage.

Okorokov AL, Rubbi CP, Metcalfe S, Milner J.

Oncogene. 2002 Jan 17;21(3):356-67.

23.

p53 binds the nuclear matrix in normal cells: binding involves the proline-rich domain of p53 and increases following genotoxic stress.

Jiang M, Axe T, Holgate R, Rubbi CP, Okorokov AL, Mee T, Milner J.

Oncogene. 2001 Sep 6;20(39):5449-58.

24.

Human topoisomerase IIalpha and IIbeta interact with the C-terminal region of p53.

Cowell IG, Okorokov AL, Cutts SA, Padget K, Bell M, Milner J, Austin CA.

Exp Cell Res. 2000 Feb 25;255(1):86-94.

PMID:
10666337
26.

An ATP/ADP-dependent molecular switch regulates the stability of p53-DNA complexes.

Okorokov AL, Milner J.

Mol Cell Biol. 1999 Nov;19(11):7501-10.

27.

Proteolytic cleavage of p53 mutants in response to mismatched DNA.

Mee T, Okorokov AL, Metcalfe S, Milner J.

Br J Cancer. 1999 Sep;81(2):212-8.

28.

Wild-type p53 protein shows calcium-dependent binding to F-actin.

Metcalfe S, Weeds A, Okorokov AL, Milner J, Cockman M, Pope B.

Oncogene. 1999 Apr 8;18(14):2351-5.

30.

RNA cleavage without hydrolysis. Splitting the catalytic activities of binase with Asn101 and Thr101 mutations.

Okorokov AL, Panov KI, Offen WA, Mukhortov VG, Antson AA, Karpeisky MYa, Wilkinson AJ, Dodson GG.

Protein Eng. 1997 Mar;10(3):273-8.

PMID:
9153077
31.

Proteolytic cleavage of p53: a model for the activation of p53 in response to DNA damage.

Okorokov AL, Milner J.

Oncol Res. 1997;9(6-7):267-73. Review.

PMID:
9406231
32.

Ribonuclease A mutant His119 Asn: the role of histidine in catalysis.

Panov KI, Kolbanovskaya EY, Okorokov AL, Panova TB, Terwisscha van Scheltinga AC, Karpeisky MYa, Beintema JJ.

FEBS Lett. 1996 Nov 25;398(1):57-60.

34.

Site-directed mutagenesis of the base recognition loop of ribonuclease from Bacillus intermedius (binase).

Okorokov AL, Panov KI, Kolbanovskaya EYu, Karpeisky MYa, Polyakov KM, Wilkinson AJ, Dodson GG.

FEBS Lett. 1996 Apr 15;384(2):143-6.

35.

An efficient system for active bovine pancreatic ribonuclease expression in Escherichia coli.

Okorokov AL, Panov KI, te Poele RH, Breukelman HJ, Furia A, Karpeisky MYa, Beintema JJ.

Protein Expr Purif. 1995 Aug;6(4):472-80.

PMID:
8527933
36.

An improved system for ribonuclease Ba expression.

Okorokov AL, Hartley RW, Panov KI.

Protein Expr Purif. 1994 Dec;5(6):547-52.

PMID:
7858423
37.

An approach to construction of hybrid polypeptide molecules--homologue recombination method.

Schulga AA, Levichkin IV, Kurkbanov FT, Okorokov AL, Pozmogova GE, Kirpichnikov MP.

Nucleic Acids Res. 1994 Sep 11;22(18):3808-10. No abstract available.

38.

[Barnase mutant Ser57Ala: preparation and properties].

Kolbanovskaia EIu, Okorokov AL, Panov KI, Poliakov KM, Hartley RW, Karpeĭskiĭ MIa.

Mol Biol (Mosk). 1994 May-Jun;28(3):602-9. Russian.

PMID:
8052251
39.

[Superproduction of Bacillus intermedius 7P ribonuclease (binase) in Escherichia coli].

Shul'ga AA, Okorokov AL, Panov KI, Kurbanov FT, Chernov BK, Skriabin KG, Kirpichnikov MP.

Mol Biol (Mosk). 1994 Mar-Apr;28(2):453-63. Russian.

PMID:
8183278
40.

[Cloning the asd and lysC genes from Cornyebacterium glutamicum].

Peredel'chuk MIu, Bukanov NO, Smirnov IuV, Rostova IuV, Fedorova ND, Okorokov AL, Gusiatiner MM, Iankovskiĭ NK.

Mol Gen Mikrobiol Virusol. 1992 May-Jun;(5-6):25-7. Russian.

PMID:
1454080
41.

[Use of a phage-plasmid vector for studying the expression of genes coding for the biosynthesis of threonine by Corynebacterium glutamicum in the mini-cell Escherichia coli system].

Okorokov AL, Bukanov NO, Beskrovnaia OIu, Iankovskiĭ NK.

Mol Gen Mikrobiol Virusol. 1991 Jan;(1):19-21. Russian. No abstract available.

PMID:
1902549
42.

[Development of the vector-host system in Corynebacterium. Cloning and expression of homoserine dehydrogenase and homoserine kinase genes in Corynebacterium cells].

Okorokov AL, Bukanov NO, Beskrovnaia OIu, Voroshilova EB, Gusiatiner MM, Gritsenko VG, Iankovskiĭ NK, Debabov VG.

Genetika. 1990 Apr;26(4):648-56. Russian.

PMID:
2165016
43.

[Cloning and structural-functional analysis in Escherichia coli of genes of glutamate-producing corynebacteria controlling biosynthesis of amino acids of aspartic acid series].

Beskrovnaia OIu, Bukanov NO, Fonshteĭn MIu, Gusiatiner MM, Okorokov AL, Nashchokina OO, Iankovskiĭ NK.

Genetika. 1990 Mar;26(3):412-7. Russian.

PMID:
2191895
44.

[Cloning and study of Corynebacterium glutamicum genes complementing ilvA and thrA2 mutations in Escherichia coli].

Beskrovnaia OIu, Bukanov NO, Okorokov AL, Fonshteĭn MIu, Iankovskiĭ NK.

Genetika. 1989 Jan;25(1):49-56. Russian.

PMID:
2659439

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