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Items: 1 to 50 of 103

1.

Novel Segment- and Host-Specific Patterns of Enteroaggregative Escherichia coli Adherence to Human Intestinal Enteroids.

Rajan A, Vela L, Zeng XL, Yu X, Shroyer N, Blutt SE, Poole NM, Carlin LG, Nataro JP, Estes MK, Okhuysen PC, Maresso AW.

MBio. 2018 Feb 20;9(1). pii: e02419-17. doi: 10.1128/mBio.02419-17.

2.

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.

Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA.

Science. 2018 Jan 5;359(6371):97-103. doi: 10.1126/science.aan4236. Epub 2017 Nov 2.

3.

Clinical features and molecular epidemiology of diarrheagenic Escherichia coli pathotypes identified by fecal gastrointestinal multiplex nucleic acid amplification in patients with cancer and diarrhea.

Chao AW, Bhatti M, DuPont HL, Nataro JP, Carlin LG, Okhuysen PC.

Diagn Microbiol Infect Dis. 2017 Nov;89(3):235-240. doi: 10.1016/j.diagmicrobio.2017.08.004. Epub 2017 Aug 12.

PMID:
28931467
4.

Viral associated diarrhea in immunocompromised and cancer patients at a large comprehensive cancer center: a 10-year retrospective study.

Ghosh N, Malik FA, Daver RG, Vanichanan J, Okhuysen PC.

Infect Dis (Lond). 2017 Feb;49(2):113-119. Epub 2016 Sep 13.

PMID:
27620005
5.

Fecal Indole as a Biomarker of Susceptibility to Cryptosporidium Infection.

Chappell CL, Darkoh C, Shimmin L, Farhana N, Kim DK, Okhuysen PC, Hixson J.

Infect Immun. 2016 Jul 21;84(8):2299-306. doi: 10.1128/IAI.00336-16. Print 2016 Aug.

6.

Cryptosporidium muris: infectivity and illness in healthy adult volunteers.

Chappell CL, Okhuysen PC, Langer-Curry RC, Lupo PJ, Widmer G, Tzipori S.

Am J Trop Med Hyg. 2015 Jan;92(1):50-5. doi: 10.4269/ajtmh.14-0525. Epub 2014 Oct 13.

7.

Persistent abdominal symptoms in US adults after short-term stay in Mexico.

Nair P, Okhuysen PC, Jiang ZD, Carlin LG, Belkind-Gerson J, Flores J, Paredes M, DuPont HL.

J Travel Med. 2014 May-Jun;21(3):153-8. doi: 10.1111/jtm.12114. Epub 2014 Mar 13.

8.

Seroepidemiology of norovirus-associated travelers' diarrhea.

Ajami NJ, Kavanagh OV, Ramani S, Crawford SE, Atmar RL, Jiang ZD, Okhuysen PC, Estes MK, DuPont HL.

J Travel Med. 2014 Jan-Feb;21(1):6-11. doi: 10.1111/jtm.12092.

9.

Does chemotherapy cause viral relapse in cancer patients with hepatitis C infection successfully treated with antivirals?

Mahale P, Okhuysen PC, Torres HA.

Clin Gastroenterol Hepatol. 2014 Jun;12(6):1051-4.e1. doi: 10.1016/j.cgh.2013.10.034. Epub 2013 Nov 7.

PMID:
24211293
10.

Enteropathogens and chronic illness in returning travelers.

Cabada MM, Okhuysen PC, White AC Jr.

N Engl J Med. 2013 Aug 22;369(8):783. doi: 10.1056/NEJMc1308293. No abstract available.

PMID:
23964950
11.

Mechanism of action and initial evaluation of a membrane active all-D-enantiomer antimicrobial peptidomimetic.

McGrath DM, Barbu EM, Driessen WH, Lasco TM, Tarrand JJ, Okhuysen PC, Kontoyiannis DP, Sidman RL, Pasqualini R, Arap W.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3477-82. doi: 10.1073/pnas.1221924110. Epub 2013 Jan 23.

12.

A randomized, double-blind, pilot study of rifaximin 550 mg versus placebo in the prevention of travelers' diarrhea in Mexico during the dry season.

Flores J, Dupont HL, Jiang ZD, Okhuysen PC, Melendez-Romero JH, Gonzalez-Estrada A, Carrillo I, Paredes M.

J Travel Med. 2011 Sep-Oct;18(5):333-6. doi: 10.1111/j.1708-8305.2011.00549.x. Epub 2011 Aug 1.

13.

Patterns of illness in travelers visiting Mexico and Central America: the GeoSentinel experience.

Flores-Figueroa J, Okhuysen PC, von Sonnenburg F, DuPont HL, Libman MD, Keystone JS, Hale DC, Burchard G, Han PV, Wilder-Smith A, Freedman DO; GeoSentinel Surveillance Network.

Clin Infect Dis. 2011 Sep;53(6):523-31. doi: 10.1093/cid/cir468. Epub 2011 Aug 10.

14.

Cryptosporidium meleagridis: infectivity in healthy adult volunteers.

Chappell CL, Okhuysen PC, Langer-Curry RC, Akiyoshi DE, Widmer G, Tzipori S.

Am J Trop Med Hyg. 2011 Aug;85(2):238-42. doi: 10.4269/ajtmh.2011.10-0664.

15.

Single nucleotide polymorphisms in the promoter of the gene encoding the lipopolysaccharide receptor CD14 are associated with bacterial diarrhea in US and Canadian travelers to Mexico.

Mohamed JA, DuPont HL, Flores J, Palur H, Nair P, Jiang ZD, Guo D, Belkind-Gerson J, Okhuysen PC.

Clin Infect Dis. 2011 Jun;52(11):1332-41. doi: 10.1093/cid/cir228.

16.

Seasonality of diarrheagenic Escherichia coli pathotypes in the US students acquiring diarrhea in Mexico.

Paredes-Paredes M, Okhuysen PC, Flores J, Mohamed JA, Padda RS, Gonzalez-Estrada A, Haley CA, Carlin LG, Nair P, DuPont HL.

J Travel Med. 2011 Mar-Apr;18(2):121-5. doi: 10.1111/j.1708-8305.2010.00488.x. Epub 2011 Feb 7.

17.

Campylobacter jejuni is not an important pathogen as a cause of diarrhea in US travelers to Mexico.

Villa NA, Okhuysen PC, Flores-Figueroa J, Jiang ZD, Belkind-Gerson J, Paredes M, Mohamed JA, Nair P, Carlin L, DuPont HL.

J Travel Med. 2011 Jan-Feb;18(1):56-8. doi: 10.1111/j.1708-8305.2010.00469.x. Epub 2010 Nov 22.

18.

Enteroaggregative Escherichia coli (EAEC): a cause of acute and persistent diarrhea of worldwide importance.

Okhuysen PC, Dupont HL.

J Infect Dis. 2010 Aug 15;202(4):503-5. doi: 10.1086/654895. No abstract available.

PMID:
20594108
19.

Characterization of norovirus-associated traveler's diarrhea.

Ajami N, Koo H, Darkoh C, Atmar RL, Okhuysen PC, Jiang ZD, Flores J, Dupont HL.

Clin Infect Dis. 2010 Jul 15;51(2):123-30. doi: 10.1086/653530.

20.

Biochemical and genetic diversity of enterotoxigenic Escherichia coli associated with diarrhea in United States students in Cuernavaca and Guadalajara, Mexico, 2004-2007.

Ouyang-Latimer J, Ajami NJ, Jiang ZD, Okhuysen PC, Paredes M, Flores J, Dupont HL.

J Infect Dis. 2010 Jun 15;201(12):1831-8. doi: 10.1086/652797.

PMID:
20443738
21.

Prevention of travelers' diarrhea with rifaximin in US travelers to Mexico.

Martinez-Sandoval F, Ericsson CD, Jiang ZD, Okhuysen PC, Romero JH, Hernandez N, Forbes WP, Shaw A, Bortey E, DuPont HL.

J Travel Med. 2010 Mar-Apr;17(2):111-7. doi: 10.1111/j.1708-8305.2009.00385.x.

22.

Noroviruses as a cause of diarrhea in travelers to Guatemala, India, and Mexico.

Koo HL, Ajami NJ, Jiang ZD, Neill FH, Atmar RL, Ericsson CD, Okhuysen PC, Taylor DN, Bourgeois AL, Steffen R, DuPont HL.

J Clin Microbiol. 2010 May;48(5):1673-6. doi: 10.1128/JCM.02072-09. Epub 2010 Mar 19.

23.

Pilot study of whole-blood gamma interferon response to the Vibrio cholerae toxin B subunit and resistance to enterotoxigenic Escherichia coli-associated diarrhea.

Flores J, DuPont HL, Paredes-Paredes M, Aguirre-Garcia MM, Rojas A, Gonzalez A, Okhuysen PC.

Clin Vaccine Immunol. 2010 May;17(5):879-81. doi: 10.1128/CVI.00486-09. Epub 2010 Mar 10.

24.

Genetics of susceptibility to infection with enteric pathogens.

Flores J, Okhuysen PC.

Curr Opin Infect Dis. 2009 Oct;22(5):471-6. doi: 10.1097/QCO.0b013e3283304eb6. Review.

25.
26.

Enteroaggregative Escherichia coli infection.

Flores J, Okhuysen PC.

Curr Opin Gastroenterol. 2009 Jan;25(1):8-11. doi: 10.1097/MOG.0b013e32831dac5e. Review.

PMID:
19114769
27.

Epidemiology of cryptosporidiosis in North American travelers to Mexico.

Nair P, Mohamed JA, DuPont HL, Figueroa JF, Carlin LG, Jiang ZD, Belkind-Gerson J, Martinez-Sandoval FG, Okhuysen PC.

Am J Trop Med Hyg. 2008 Aug;79(2):210-4.

28.

A functional collagen adhesin gene, acm, in clinical isolates of Enterococcus faecium correlates with the recent success of this emerging nosocomial pathogen.

Nallapareddy SR, Singh KV, Okhuysen PC, Murray BE.

Infect Immun. 2008 Sep;76(9):4110-9. doi: 10.1128/IAI.00375-08. Epub 2008 Jun 30.

29.

Influence of host interleukin-10 polymorphisms on development of traveler's diarrhea due to heat-labile enterotoxin-producing Escherichia coli in travelers from the United States who are visiting Mexico.

Flores J, DuPont HL, Lee SA, Belkind-Gerson J, Paredes M, Mohamed JA, Armitige LY, Guo DC, Okhuysen PC.

Clin Vaccine Immunol. 2008 Aug;15(8):1194-8. doi: 10.1128/CVI.00070-08. Epub 2008 Jun 25.

30.

Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial.

Frech SA, Dupont HL, Bourgeois AL, McKenzie R, Belkind-Gerson J, Figueroa JF, Okhuysen PC, Guerrero NH, Martinez-Sandoval FG, Meléndez-Romero JH, Jiang ZD, Asturias EJ, Halpern J, Torres OR, Hoffman AS, Villar CP, Kassem RN, Flyer DC, Andersen BH, Kazempour K, Breisch SA, Glenn GM.

Lancet. 2008 Jun 14;371(9629):2019-25. doi: 10.1016/S0140-6736(08)60839-9.

PMID:
18554712
31.

Cryptosporidium muris in a Texas canine population.

Lupo PJ, Langer-Curry RC, Robinson M, Okhuysen PC, Chappell CL.

Am J Trop Med Hyg. 2008 Jun;78(6):917-21.

PMID:
18541769
32.

Enterotoxigenic Escherichia coli heat-labile toxin seroconversion in US travelers to Mexico.

Flores J, DuPont HL, Jiang ZD, Belkind-Gerson J, Mohamed JA, Carlin LG, Padda RS, Paredes M, Martinez-Sandoval JF, Villa NA, Okhuysen PC.

J Travel Med. 2008 May-Jun;15(3):156-61. doi: 10.1111/j.1708-8305.2008.00187.x.

33.

PCR-based assay using occult blood detection cards for detection of diarrheagenic Escherichia coli in specimens from U.S. travelers to Mexico with acute diarrhea.

Grimes KA, Mohamed JA, Dupont HL, Padda RS, Jiang ZD, Flores J, Belkind-Gerson J, Martinez-Sandoval FG, Okhuysen PC.

J Clin Microbiol. 2008 Jul;46(7):2227-30. doi: 10.1128/JCM.00073-08. Epub 2008 May 14.

34.

Seroprevalence of the enteroaggregative Escherichia coli virulence factor dispersin among USA travellers to Cuernavaca, Mexico: a pilot study.

Huang DB, Brown EL, DuPont HL, Cerf J, Carlin L, Flores J, Belkind-Gerson J, Nataro JP, Okhuysen PC.

J Med Microbiol. 2008 Apr;57(Pt 4):476-9. doi: 10.1099/jmm.0.47495-0.

PMID:
18349368
35.

Virulence characteristics and the molecular epidemiology of enteroaggregative Escherichia coli isolates from travellers to developing countries.

Huang DB, Mohamed JA, Nataro JP, DuPont HL, Jiang ZD, Okhuysen PC.

J Med Microbiol. 2007 Oct;56(Pt 10):1386-92.

PMID:
17893178
36.

Loperamide plus azithromycin more effectively treats travelers' diarrhea in Mexico than azithromycin alone.

Ericsson CD, DuPont HL, Okhuysen PC, Jiang ZD, DuPont MW.

J Travel Med. 2007 Sep-Oct;14(5):312-9.

37.

Treatment of travelers' diarrhea: randomized trial comparing rifaximin, rifaximin plus loperamide, and loperamide alone.

Dupont HL, Jiang ZD, Belkind-Gerson J, Okhuysen PC, Ericsson CD, Ke S, Huang DB, Dupont MW, Adachi JA, De La Cabada FJ, Taylor DN, Jaini S, Martinez Sandoval F.

Clin Gastroenterol Hepatol. 2007 Apr;5(4):451-6. Epub 2007 Mar 26.

PMID:
17382603
38.

A novel single-nucleotide polymorphism in the lactoferrin gene is associated with susceptibility to diarrhea in North American travelers to Mexico.

Mohamed JA, DuPont HL, Jiang ZD, Belkind-Gerson J, Figueroa JF, Armitige LY, Tsai A, Nair P, Martinez-Sandoval FJ, Guo DC, Hayes P, Okhuysen PC.

Clin Infect Dis. 2007 Apr 1;44(7):945-52. Epub 2007 Feb 20.

PMID:
17342646
39.

Cryptosporidium parvum: identification and characterization of an acid phosphatase.

Aguirre-García MM, Okhuysen PC.

Parasitol Res. 2007 Jun;101(1):85-9. Epub 2007 Jan 25.

PMID:
17252269
40.

Rifaximin treatment of pathogen-negative travelers' diarrhea.

DuPont HL, Haake R, Taylor DN, Ericsson CD, Jiang ZD, Okhuysen PC, Steffen R.

J Travel Med. 2007 Jan-Feb;14(1):16-9.

41.

Cryptosporidium hominis: experimental challenge of healthy adults.

Chappell CL, Okhuysen PC, Langer-Curry R, Widmer G, Akiyoshi DE, Tanriverdi S, Tzipori S.

Am J Trop Med Hyg. 2006 Nov;75(5):851-7.

PMID:
17123976
42.

Association of putative enteroaggregative Escherichia coli virulence genes and biofilm production in isolates from travelers to developing countries.

Mohamed JA, Huang DB, Jiang ZD, DuPont HL, Nataro JP, Belkind-Gerson J, Okhuysen PC.

J Clin Microbiol. 2007 Jan;45(1):121-6. Epub 2006 Nov 8.

43.

High levels of CXCL10 are produced by intestinal epithelial cells in AIDS patients with active cryptosporidiosis but not after reconstitution of immunity.

Wang HC, Dann SM, Okhuysen PC, Lewis DE, Chappell CL, Adler DG, White AC Jr.

Infect Immun. 2007 Jan;75(1):481-7. Epub 2006 Oct 16.

44.

Parasitic infections of the intestines.

Okhuysen PC, White AC Jr.

Curr Opin Infect Dis. 1999 Oct;12(5):467-72.

PMID:
17035813
45.

A review of an emerging enteric pathogen: enteroaggregative Escherichia coli.

Huang DB, Mohanty A, DuPont HL, Okhuysen PC, Chiang T.

J Med Microbiol. 2006 Oct;55(Pt 10):1303-11. Review. Erratum in: J Med Microbiol. 2007 Jan;56(Pt 1):142.

PMID:
17005776
46.

Enteroaggregative Escherichia coli is a cause of acute diarrheal illness: a meta-analysis.

Huang DB, Nataro JP, DuPont HL, Kamat PP, Mhatre AD, Okhuysen PC, Chiang T.

Clin Infect Dis. 2006 Sep 1;43(5):556-63. Epub 2006 Jul 28.

PMID:
16886146
47.

Fecal cytokines and markers of intestinal inflammation in international travelers with diarrhea due to Noroviruses.

Ko G, Jiang ZD, Okhuysen PC, DuPont HL.

J Med Virol. 2006 Jun;78(6):825-8.

PMID:
16628572
48.

Noroviruses as a cause of traveler's diarrhea among students from the United States visiting Mexico.

Ko G, Garcia C, Jiang ZD, Okhuysen PC, Belkind-Gerson J, Glass RI, DuPont HL.

J Clin Microbiol. 2005 Dec;43(12):6126-9.

49.

Antibacterial chemoprophylaxis in the prevention of traveler's diarrhea: evaluation of poorly absorbed oral rifaximin.

DuPont HL, Jiang ZD, Okhuysen PC, Ericsson CD, de la Cabada FJ, Ke S, DuPont MW, Martinez-Sandoval F.

Clin Infect Dis. 2005 Dec 1;41 Suppl 8:S571-6.

PMID:
16267721
50.

Current concepts in travelers' diarrhea: epidemiology, antimicrobial resistance and treatment.

Okhuysen PC.

Curr Opin Infect Dis. 2005 Dec;18(6):522-6. Review.

PMID:
16258326

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