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Items: 34


Proteomics profiling of autologous blood and semen exosomes from HIV-infected and uninfected individuals reveals compositional and functional variabilities.

Kaddour H, Lyu Y, Welch JL, Paromov V, Mandape SN, Sakhare SS, Pandhare J, Stapleton JT, Pratap S, Dash C, Okeoma CM.

Mol Cell Proteomics. 2019 Nov 1. pii: mcp.RA119.001594. doi: 10.1074/mcp.RA119.001594. [Epub ahead of print]


Semen exosomes inhibit HIV infection and HIV-induced proinflammatory cytokine production independently of the activation state of primary lymphocytes.

Welch JL, Kaufman TM, Stapleton JT, Okeoma CM.

FEBS Lett. 2019 Oct 30. doi: 10.1002/1873-3468.13653. [Epub ahead of print]


Human Immunodeficiency Virus (HIV) Infection and Use of Illicit Substances Promote Secretion of Semen Exosomes that Enhance Monocyte Adhesion and Induce Actin Reorganization and Chemotactic Migration.

Lyu Y, Kaddour H, Kopcho S, Panzner TD, Shouman N, Kim EY, Martinson J, McKay H, Martinez-Maza O, Margolick JB, Stapleton JT, Okeoma CM.

Cells. 2019 Sep 3;8(9). pii: E1027. doi: 10.3390/cells8091027.


Vehicles of intercellular communication: exosomes and HIV-1.

Welch JL, Stapleton JT, Okeoma CM.

J Gen Virol. 2019 Mar;100(3):350-366. doi: 10.1099/jgv.0.001193. Epub 2019 Jan 31.


BST-2 promotes survival in circulation and pulmonary metastatic seeding of breast cancer cells.

Mahauad-Fernandez WD, Naushad W, Panzner TD, Bashir A, Lal G, Okeoma CM.

Sci Rep. 2018 Dec 4;8(1):17608. doi: 10.1038/s41598-018-35710-y.


Semen Exosomes Promote Transcriptional Silencing of HIV-1 by Disrupting NF-κB/Sp1/Tat Circuitry.

Welch JL, Kaddour H, Schlievert PM, Stapleton JT, Okeoma CM.

J Virol. 2018 Oct 12;92(21). pii: e00731-18. doi: 10.1128/JVI.00731-18. Print 2018 Nov 1.


B49, a BST-2-based peptide, inhibits adhesion and growth of breast cancer cells.

Mahauad-Fernandez WD, Okeoma CM.

Sci Rep. 2018 Mar 9;8(1):4305. doi: 10.1038/s41598-018-22364-z.


Structural determinant of BST-2-mediated regulation of breast cancer cell motility: a role for cytoplasmic tail tyrosine residues.

Naushad W, Mahauad-Fernandez WD, Okeoma CM.

Oncotarget. 2017 Nov 29;8(66):110221-110233. doi: 10.18632/oncotarget.22753. eCollection 2017 Dec 15.


Isolation of Exosomes from Semen for in vitro Uptake and HIV-1 Infection Assays.

Madison MN, Welch JL, Okeoma CM.

Bio Protoc. 2017 Apr 5;7(7). pii: e2216. doi: 10.21769/BioProtoc.2216.


Effect of prolonged freezing of semen on exosome recovery and biologic activity.

Welch JL, Madison MN, Margolick JB, Galvin S, Gupta P, Martínez-Maza O, Dash C, Okeoma CM.

Sci Rep. 2017 Mar 24;7:45034. doi: 10.1038/srep45034.


The role of BST-2/Tetherin in host protection and disease manifestation.

Mahauad-Fernandez WD, Okeoma CM.

Immun Inflamm Dis. 2015 Dec 7;4(1):4-23. doi: 10.1002/iid3.92. eCollection 2016 Mar. Review.


Exosomes: Implications in HIV-1 Pathogenesis.

Madison MN, Okeoma CM.

Viruses. 2015 Jul 20;7(7):4093-118. doi: 10.3390/v7072810. Review.


Exosomes in human semen restrict HIV-1 transmission by vaginal cells and block intravaginal replication of LP-BM5 murine AIDS virus complex.

Madison MN, Jones PH, Okeoma CM.

Virology. 2015 Aug;482:189-201. doi: 10.1016/j.virol.2015.03.040. Epub 2015 Apr 13.


Bone marrow stromal antigen 2 (BST-2) DNA is demethylated in breast tumors and breast cancer cells.

Mahauad-Fernandez WD, Borcherding NC, Zhang W, Okeoma CM.

PLoS One. 2015 Apr 10;10(4):e0123931. doi: 10.1371/journal.pone.0123931. eCollection 2015.


Bone marrow stromal antigen 2 expressed in cancer cells promotes mammary tumor growth and metastasis.

Mahauad-Fernandez WD, DeMali KA, Olivier AK, Okeoma CM.

Breast Cancer Res. 2014 Dec 13;16(6):493. doi: 10.1186/s13058-014-0493-8.


Human semen contains exosomes with potent anti-HIV-1 activity.

Madison MN, Roller RJ, Okeoma CM.

Retrovirology. 2014 Nov 19;11:102. doi: 10.1186/s12977-014-0102-z.


Critical role for bone marrow stromal antigen 2 in acute Chikungunya virus infection.

Mahauad-Fernandez WD, Jones PH, Okeoma CM.

J Gen Virol. 2014 Nov;95(Pt 11):2450-61. doi: 10.1099/vir.0.068643-0. Epub 2014 Jul 22.


Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated BST-2/tetherin regulation.

Jones PH, Okeoma CM.

Cell Signal. 2013 Dec;25(12):2752-61. doi: 10.1016/j.cellsig.2013.08.042. Epub 2013 Sep 13.


BST-2/tetherin is overexpressed in mammary gland and tumor tissues in MMTV-induced mammary cancer.

Jones PH, Mahauad-Fernandez WD, Madison MN, Okeoma CM.

Virology. 2013 Sep;444(1-2):124-39. doi: 10.1016/j.virol.2013.05.042. Epub 2013 Jun 25.


BST-2/tetherin-mediated restriction of chikungunya (CHIKV) VLP budding is counteracted by CHIKV non-structural protein 1 (nsP1).

Jones PH, Maric M, Madison MN, Maury W, Roller RJ, Okeoma CM.

Virology. 2013 Mar 30;438(1):37-49. doi: 10.1016/j.virol.2013.01.010. Epub 2013 Feb 12.


IFN-α and lipopolysaccharide upregulate APOBEC3 mRNA through different signaling pathways.

Mehta HV, Jones PH, Weiss JP, Okeoma CM.

J Immunol. 2012 Oct 15;189(8):4088-103. doi: 10.4049/jimmunol.1200777. Epub 2012 Sep 12.


Bone marrow stromal cell antigen 2 (BST-2) restricts mouse mammary tumor virus (MMTV) replication in vivo.

Jones PH, Mehta HV, Maric M, Roller RJ, Okeoma CM.

Retrovirology. 2012 Jan 27;9:10. doi: 10.1186/1742-4690-9-10.


APOBEC3 proteins expressed in mammary epithelial cells are packaged into retroviruses and can restrict transmission of milk-borne virions.

Okeoma CM, Huegel AL, Lingappa J, Feldman MD, Ross SR.

Cell Host Microbe. 2010 Dec 16;8(6):534-43. doi: 10.1016/j.chom.2010.11.003.


Induction of APOBEC3 in vivo causes increased restriction of retrovirus infection.

Okeoma CM, Low A, Bailis W, Fan HY, Peterlin BM, Ross SR.

J Virol. 2009 Apr;83(8):3486-95. doi: 10.1128/JVI.02347-08. Epub 2009 Jan 19.


Expression of murine APOBEC3 alleles in different mouse strains and their effect on mouse mammary tumor virus infection.

Okeoma CM, Petersen J, Ross SR.

J Virol. 2009 Apr;83(7):3029-38. doi: 10.1128/JVI.02536-08. Epub 2009 Jan 19.


Enhanced replication and pathogenesis of Moloney murine leukemia virus in mice defective in the murine APOBEC3 gene.

Low A, Okeoma CM, Lovsin N, de las Heras M, Taylor TH, Peterlin BM, Ross SR, Fan H.

Virology. 2009 Mar 15;385(2):455-63. doi: 10.1016/j.virol.2008.11.051. Epub 2009 Jan 15.


A novel block to mouse mammary tumor virus infection of lymphocytes in B10.BR mice.

Okeoma CM, Shen M, Ross SR.

J Virol. 2008 Feb;82(3):1314-22. Epub 2007 Nov 14.


APOBEC3 inhibits mouse mammary tumour virus replication in vivo.

Okeoma CM, Lovsin N, Peterlin BM, Ross SR.

Nature. 2007 Feb 22;445(7130):927-30. Epub 2007 Jan 28.


Neospora caninum: quantification of DNA in the blood of naturally infected aborted and pregnant cows using real-time PCR.

Okeoma CM, Stowell KM, Williamson NB, Pomroy WE.

Exp Parasitol. 2005 May;110(1):48-55.


Isolation and molecular characterisation of Neospora caninum in cattle in New Zealand.

Okeoma CM, Williamson NB, Pomroy WE, Stowell KM, Gillespie LM.

N Z Vet J. 2004 Dec;52(6):364-70.


Recognition patterns of Neospora caninum tachyzoite antigens by bovine IgG at different IFAT titres.

Okeoma CM, Williamson NB, Pomroy WE, Stowell KM.

Parasite Immunol. 2004 Apr;26(4):177-85.


The use of PCR to detect Neospora caninum DNA in the blood of naturally infected cows.

Okeoma CM, Williamson NB, Pomroy WE, Stowell KM, Gillespie L.

Vet Parasitol. 2004 Aug 6;122(4):307-15.


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