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Items: 1 to 50 of 405

1.

Methods to Image Macroautophagy in the Brain In Vivo.

Chen X, Kondo K, Okazawa H.

Methods Mol Biol. 2019;1880:529-534. doi: 10.1007/978-1-4939-8873-0_33.

PMID:
30610719
2.

Drebrin-like (Dbnl) controls neuronal migration via regulating N-cadherin expression in the developing cerebral cortex.

Inoue S, Hayashi K, Fujita K, Tagawa K, Okazawa H, Kubo KI, Nakajima K.

J Neurosci. 2018 Nov 30. pii: 1634-18. doi: 10.1523/JNEUROSCI.1634-18.2018. [Epub ahead of print]

PMID:
30504273
3.

The intellectual disability gene PQBP1 rescues Alzheimer's disease pathology.

Tanaka H, Kondo K, Chen X, Homma H, Tagawa K, Kerever A, Aoki S, Saito T, Saido T, Muramatsu SI, Fujita K, Okazawa H.

Mol Psychiatry. 2018 Oct;23(10):2090-2110. doi: 10.1038/s41380-018-0253-8. Epub 2018 Oct 3.

4.

Count-based method for specific binding ratio calculation in [I-123]FP-CIT SPECT analysis.

Rahman MGM, Islam MM, Tsujikawa T, Kiyono Y, Okazawa H.

Ann Nucl Med. 2019 Jan;33(1):14-21. doi: 10.1007/s12149-018-1297-1. Epub 2018 Oct 1.

5.

Suppression of the synaptic localization of a subset of proteins including APP partially ameliorates phenotypes of the Drosophila Alzheimer's disease model.

Furotani K, Kamimura K, Yajima T, Nakayama M, Enomoto R, Tamura T, Okazawa H, Sone M.

PLoS One. 2018 Sep 18;13(9):e0204048. doi: 10.1371/journal.pone.0204048. eCollection 2018.

6.

Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology.

Fujita K, Homma H, Kondo K, Ikuno M, Yamakado H, Tagawa K, Murayama S, Takahashi R, Okazawa H.

eNeuro. 2018 Sep 4;5(4). pii: ENEURO.0217-18.2018. doi: 10.1523/ENEURO.0217-18.2018. eCollection 2018 Jul-Aug.

7.

Arterial spin labeling MR imaging for the clinical detection of cerebellar hypoperfusion in patients with spinocerebellar degeneration.

Ikawa M, Kimura H, Kitazaki Y, Sugimoto K, Matsunaga A, Hayashi K, Yamamura O, Tsujikawa T, Hamano T, Yoneda M, Okazawa H, Nakamoto Y.

J Neurol Sci. 2018 Nov 15;394:58-62. doi: 10.1016/j.jns.2018.09.007. Epub 2018 Sep 6.

PMID:
30216759
8.

Altered perspective-dependent brain activation while viewing hands and associated imitation difficulties in individuals with autism spectrum disorder.

Okamoto Y, Kitada R, Miyahara M, Kochiyama T, Naruse H, Sadato N, Okazawa H, Kosaka H.

Neuroimage Clin. 2018 Apr 27;19:384-395. doi: 10.1016/j.nicl.2018.04.030. eCollection 2018.

9.

Noninvasive method for measurement of cerebral blood flow using O-15 water PET/MRI with ASL correlation.

Okazawa H, Higashino Y, Tsujikawa T, Arishima H, Mori T, Kiyono Y, Kimura H, Kikuta KI.

Eur J Radiol. 2018 Aug;105:102-109. doi: 10.1016/j.ejrad.2018.05.033. Epub 2018 Jun 1.

PMID:
30017265
10.

Search for Boosted Dark Matter Interacting with Electrons in Super-Kamiokande.

Kachulis C, Abe K, Bronner C, Hayato Y, Ikeda M, Iyogi K, Kameda J, Kato Y, Kishimoto Y, Marti L, Miura M, Moriyama S, Nakahata M, Nakano Y, Nakayama S, Okajima Y, Orii A, Pronost G, Sekiya H, Shiozawa M, Sonoda Y, Takeda A, Takenaka A, Tanaka H, Tasaka S, Tomura T, Akutsu R, Kajita T, Kaneyuki K, Nishimura Y, Okumura K, Tsui KM, Labarga L, Fernandez P, Blaszczyk FDM, Gustafson J, Kearns E, Raaf JL, Stone JL, Sulak LR, Berkman S, Tobayama S, Goldhaber M, Elnimr M, Kropp WR, Mine S, Locke S, Weatherly P, Smy MB, Sobel HW, Takhistov V, Ganezer KS, Hill J, Kim JY, Lim IT, Park RG, Himmel A, Li Z, O'Sullivan E, Scholberg K, Walter CW, Ishizuka T, Nakamura T, Jang JS, Choi K, Learned JG, Matsuno S, Smith SN, Amey J, Litchfield RP, Ma WY, Uchida Y, Wascko MO, Cao S, Friend M, Hasegawa T, Ishida T, Ishii T, Kobayashi T, Nakadaira T, Nakamura K, Oyama Y, Sakashita K, Sekiguchi T, Tsukamoto T, Abe KE, Hasegawa M, Suzuki AT, Takeuchi Y, Yano T, Hayashino T, Hiraki T, Hirota S, Huang K, Jiang M, Nakamura KE, Nakaya T, Quilain B, Patel ND, Wendell RA, Anthony LHV, McCauley N, Pritchard A, Fukuda Y, Itow Y, Murase M, Muto F, Mijakowski P, Frankiewicz K, Jung CK, Li X, Palomino JL, Santucci G, Vilela C, Wilking MJ, Yanagisawa C, Ito S, Fukuda D, Ishino H, Kibayashi A, Koshio Y, Nagata H, Sakuda M, Xu C, Kuno Y, Wark D, Di Lodovico F, Richards B, Tacik R, Kim SB, Cole A, Thompson L, Okazawa H, Choi Y, Ito K, Nishijima K, Koshiba M, Totsuka Y, Suda Y, Yokoyama M, Calland RG, Hartz M, Martens K, Simpson C, Suzuki Y, Vagins MR, Hamabe D, Kuze M, Yoshida T, Ishitsuka M, Martin JF, Nantais CM, Tanaka HA, Konaka A, Chen S, Wan L, Zhang Y, Wilkes RJ, Minamino A; Super-Kamiokande Collaboration.

Phys Rev Lett. 2018 Jun 1;120(22):221301. doi: 10.1103/PhysRevLett.120.221301.

11.

[The 39th Report on Survey of the Adverse Reaction to Radiopharmaceuticals (The 42nd Survey in 2016)].

Subcommittee for Safety Issues of Radiopharmaceuticals, Medical Science and Pharmaceutical Committee, Japan Radioisotope Association, Matsuda H, Uehara T, Okazawa H, Mizumura S, Yokoyama K, Yoshimura M.

Kaku Igaku. 2018;55(1):51-60. doi: 10.18893/kakuigaku.rp.1873. Japanese.

12.

Selected PET radiomic features remain the same.

Tsujikawa T, Tsuyoshi H, Kanno M, Yamada S, Kobayashi M, Narita N, Kimura H, Fujieda S, Yoshida Y, Okazawa H.

Oncotarget. 2018 Apr 17;9(29):20734-20746. doi: 10.18632/oncotarget.25070. eCollection 2018 Apr 17.

13.

Bridging Multiple Dementias.

Okazawa H.

ACS Chem Neurosci. 2018 Apr 18;9(4):636-638. doi: 10.1021/acschemneuro.8b00119. Epub 2018 Mar 20.

PMID:
29557637
14.

CT-based attenuation correction and resolution compensation for I-123 IMP brain SPECT normal database: a multicenter phantom study.

Inui Y, Ichihara T, Uno M, Ishiguro M, Ito K, Kato K, Sakuma H, Okazawa H, Toyama H.

Ann Nucl Med. 2018 Jun;32(5):311-318. doi: 10.1007/s12149-018-1248-x. Epub 2018 Mar 19.

PMID:
29556945
15.

Role of PET/MRI in oral cavity and oropharyngeal cancers based on the 8th edition of the AJCC cancer staging system: a pictorial essay.

Tsujikawa T, Narita N, Kanno M, Takabayashi T, Fujieda S, Okazawa H.

Ann Nucl Med. 2018 May;32(4):239-249. doi: 10.1007/s12149-018-1244-1. Epub 2018 Feb 27. Review.

PMID:
29488161
16.

PET probe detecting non-small cell lung cancer susceptible to epidermal growth factor receptor tyrosine kinase inhibitor therapy.

Makino A, Miyazaki A, Tomoike A, Kimura H, Arimitsu K, Hirata M, Ohmomo Y, Nishii R, Okazawa H, Kiyono Y, Ono M, Saji H.

Bioorg Med Chem. 2018 May 1;26(8):1609-1613. doi: 10.1016/j.bmc.2018.02.007. Epub 2018 Feb 8.

PMID:
29478801
17.

Role of SIRPα in Homeostatic Regulation of T Cells and Fibroblastic Reticular Cells in the Spleen.

Respatika D, Saito Y, Washio K, Komori S, Kotani T, Okazawa H, Murata Y, Matozaki T.

Kobe J Med Sci. 2017 Aug 10;63(1):E22-E29.

18.

Self-Face Recognition Begins to Share Active Region in Right Inferior Parietal Lobule with Proprioceptive Illusion During Adolescence.

Morita T, Saito DN, Ban M, Shimada K, Okamoto Y, Kosaka H, Okazawa H, Asada M, Naito E.

Cereb Cortex. 2018 Apr 1;28(4):1532-1548. doi: 10.1093/cercor/bhy027.

19.

Mild Maternal Hypothyroxinemia During Pregnancy Induces Persistent DNA Hypermethylation in the Hippocampal Brain-Derived Neurotrophic Factor Gene in Mouse Offspring.

Kawahori K, Hashimoto K, Yuan X, Tsujimoto K, Hanzawa N, Hamaguchi M, Kase S, Fujita K, Tagawa K, Okazawa H, Nakajima Y, Shibusawa N, Yamada M, Ogawa Y.

Thyroid. 2018 Mar;28(3):395-406. doi: 10.1089/thy.2017.0331.

PMID:
29415629
20.

Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.

Fujita K, Chen X, Homma H, Tagawa K, Amano M, Saito A, Imoto S, Akatsu H, Hashizume Y, Kaibuchi K, Miyano S, Okazawa H.

Nat Commun. 2018 Jan 30;9(1):433. doi: 10.1038/s41467-018-02821-z.

21.

The Relationship between Neurite Density Measured with Confocal Microscopy in a Cleared Mouse Brain and Metrics Obtained from Diffusion Tensor and Diffusion Kurtosis Imaging.

Irie R, Kamagata K, Kerever A, Ueda R, Yokosawa S, Otake Y, Ochi H, Yoshizawa H, Hayashi A, Tagawa K, Okazawa H, Takahashi K, Sato K, Hori M, Arikawa-Hirasawa E, Aoki S.

Magn Reson Med Sci. 2018 Apr 10;17(2):138-144. doi: 10.2463/mrms.mp.2017-0031. Epub 2017 Dec 7.

22.

Developmental YAPdeltaC determines adult pathology in a model of spinocerebellar ataxia type 1.

Fujita K, Mao Y, Uchida S, Chen X, Shiwaku H, Tamura T, Ito H, Watase K, Homma H, Tagawa K, Sudol M, Okazawa H.

Nat Commun. 2017 Nov 30;8(1):1864. doi: 10.1038/s41467-017-01790-z.

23.

SIRPα+ dendritic cells regulate homeostasis of fibroblastic reticular cells via TNF receptor ligands in the adult spleen.

Saito Y, Respatika D, Komori S, Washio K, Nishimura T, Kotani T, Murata Y, Okazawa H, Ohnishi H, Kaneko Y, Yui K, Yasutomo K, Nishigori C, Nojima Y, Matozaki T.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):E10151-E10160. doi: 10.1073/pnas.1711345114. Epub 2017 Nov 6.

24.

Development of Right-hemispheric Dominance of Inferior Parietal Lobule in Proprioceptive Illusion Task.

Naito E, Morita T, Saito DN, Ban M, Shimada K, Okamoto Y, Kosaka H, Okazawa H, Asada M.

Cereb Cortex. 2017 Nov 1;27(11):5385-5397. doi: 10.1093/cercor/bhx223.

25.

Assessment of intratumor heterogeneity in mesenchymal uterine tumor by an 18F-FDG PET/CT texture analysis.

Tsujikawa T, Yamamoto M, Shono K, Yamada S, Tsuyoshi H, Kiyono Y, Kimura H, Okazawa H, Yoshida Y.

Ann Nucl Med. 2017 Dec;31(10):752-757. doi: 10.1007/s12149-017-1208-x. Epub 2017 Sep 13.

PMID:
28905201
26.

Precise Evaluation of Striatal Oxidative Stress Corrected for Severity of Dopaminergic Neuronal Degeneration in Patients with Parkinson's Disease: A Study with 62Cu-ATSM PET and 123I-FP-CIT SPECT.

Neishi H, Ikawa M, Okazawa H, Tsujikawa T, Arishima H, Kikuta KI, Yoneda M.

Eur Neurol. 2017;78(3-4):161-168. doi: 10.1159/000479627. Epub 2017 Aug 24.

PMID:
28848099
27.

[Molecularly-Targeted Therapy of Spinocerebellar Ataxia Type 1 by HMGB1].

Fujita K, Okazawa H.

Brain Nerve. 2017 Aug;69(8):925-932. doi: 10.11477/mf.1416200844. Japanese.

PMID:
28819076
28.

18F-FDG PET radiomics approaches: comparing and clustering features in cervical cancer.

Tsujikawa T, Rahman T, Yamamoto M, Yamada S, Tsuyoshi H, Kiyono Y, Kimura H, Yoshida Y, Okazawa H.

Ann Nucl Med. 2017 Nov;31(9):678-685. doi: 10.1007/s12149-017-1199-7. Epub 2017 Aug 16.

PMID:
28815452
29.

The 38th Report on Survey of the Adverse Reaction to Radiopharmaceuticals (The 41st Survey in 2015).

Subcommittee for Safety Issues of Radiopharmaceuticals, Medical Science and Pharmaceutical Committee, Japan Radioisotope Association, Matsuda H, Uehara T, Okazawa H, Mizumura S, Yokoyama K, Yoshimura M.

Kaku Igaku. 2017;54(1):509-519. doi: 10.18893/kakuigaku.rp.1772. Japanese.

30.

PQBP1, an intrinsically disordered/denatured protein at the crossroad of intellectual disability and neurodegenerative diseases.

Okazawa H.

Neurochem Int. 2018 Oct;119:17-25. doi: 10.1016/j.neuint.2017.06.005. Epub 2017 Jun 13. Review.

31.

Ultra-Early Phase pathologies of Alzheimer's disease and other neurodegenerative diseases.

Okazawa H.

Proc Jpn Acad Ser B Phys Biol Sci. 2017;93(6):361-377. doi: 10.2183/pjab.93.022. Review.

32.

Highly Sensitive Telomerase Assay Insusceptible to Telomerase and Polymerase Chain Reaction Inhibitors for Cervical Cancer Screening Using Scraped Cells.

Yaku H, Yoshida Y, Okazawa H, Kiyono Y, Fujita Y, Miyoshi D.

Anal Chem. 2017 Jul 5;89(13):6948-6953. doi: 10.1021/acs.analchem.6b04777. Epub 2017 Jun 12.

PMID:
28557436
33.

Understanding microstructure of the brain by comparison of neurite orientation dispersion and density imaging (NODDI) with transparent mouse brain.

Sato K, Kerever A, Kamagata K, Tsuruta K, Irie R, Tagawa K, Okazawa H, Arikawa-Hirasawa E, Nitta N, Aoki I, Aoki S.

Acta Radiol Open. 2017 Apr 17;6(4):2058460117703816. doi: 10.1177/2058460117703816. eCollection 2017 Apr.

34.

A Novel Diagnostic Strategy Using 16α-[18F]-Fluoro-17-β-Estradiol (18F-FES) PET/MRI to Achieve Complete Resection of Intravenous Leiomyomatosis in Reproductive-Age Women.

Chino Y, Tsuyoshi H, Tsujikawa T, Okazawa H, Yoshida Y.

Clin Nucl Med. 2017 Jul;42(7):e335-e336. doi: 10.1097/RLU.0000000000001678.

PMID:
28481790
35.

Estimation of arterial input by a noninvasive image derived method in brain H215O PET study: confirmation of arterial location using MR angiography.

Islam MM, Tsujikawa T, Mori T, Kiyono Y, Okazawa H.

Phys Med Biol. 2017 May 8;62(11):4514-4524. doi: 10.1088/1361-6560/aa6a95. [Epub ahead of print]

PMID:
28480872
36.

A novel form of necrosis, TRIAD, occurs in human Huntington's disease.

Yamanishi E, Hasegawa K, Fujita K, Ichinose S, Yagishita S, Murata M, Tagawa K, Akashi T, Eishi Y, Okazawa H.

Acta Neuropathol Commun. 2017 Mar 8;5(1):19. doi: 10.1186/s40478-017-0420-1.

37.

Pixel-by-pixel precise delay correction for measurement of cerebral hemodynamic parameters in H215O PET study.

Islam MM, Tsujikawa T, Mori T, Kiyono Y, Okazawa H.

Ann Nucl Med. 2017 May;31(4):283-294. doi: 10.1007/s12149-017-1156-5. Epub 2017 Feb 27.

38.

Self-face recognition shares brain regions active during proprioceptive illusion in the right inferior fronto-parietal superior longitudinal fasciculus III network.

Morita T, Saito DN, Ban M, Shimada K, Okamoto Y, Kosaka H, Okazawa H, Asada M, Naito E.

Neuroscience. 2017 Apr 21;348:288-301. doi: 10.1016/j.neuroscience.2017.02.031. Epub 2017 Feb 24.

39.

Age-dependent atypicalities in body- and face-sensitive activation of the EBA and FFA in individuals with ASD.

Okamoto Y, Kosaka H, Kitada R, Seki A, Tanabe HC, Hayashi MJ, Kochiyama T, Saito DN, Yanaka HT, Munesue T, Ishitobi M, Omori M, Wada Y, Okazawa H, Koeda T, Sadato N.

Neurosci Res. 2017 Jun;119:38-52. doi: 10.1016/j.neures.2017.02.001. Epub 2017 Feb 11.

PMID:
28193532
40.

18F-FDG/18F-FES standardized uptake value ratio determined using PET predicts prognosis in uterine sarcoma.

Yamamoto M, Tsujikawa T, Yamada S, Kurokawa T, Shinagawa A, Chino Y, Mori T, Kiyono Y, Okazawa H, Yoshida Y.

Oncotarget. 2017 Apr 4;8(14):22581-22589. doi: 10.18632/oncotarget.15127.

41.

RpA1 ameliorates symptoms of mutant ataxin-1 knock-in mice and enhances DNA damage repair.

Taniguchi JB, Kondo K, Fujita K, Chen X, Homma H, Sudo T, Mao Y, Watase K, Tanaka T, Tagawa K, Tamura T, Muramatsu SI, Okazawa H.

Hum Mol Genet. 2016 Oct 15;25(20):4432-4447. doi: 10.1093/hmg/ddw272.

PMID:
28173122
42.

Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington's disease pathology.

Mao Y, Chen X, Xu M, Fujita K, Motoki K, Sasabe T, Homma H, Murata M, Tagawa K, Tamura T, Kaye J, Finkbeiner S, Blandino G, Sudol M, Okazawa H.

Hum Mol Genet. 2016 Nov 1;25(21):4749-4770. doi: 10.1093/hmg/ddw303.

PMID:
28171658
43.

Cerebral hyperperfusion syndrome resulting in subarachnoid hemorrhage after carotid artery stenting.

Isozaki M, Arai Y, Higashino Y, Okazawa H, Kikuta KI.

Ann Nucl Med. 2016 Nov;30(9):669-674. Epub 2016 Aug 2.

PMID:
27485406
44.

Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries.

Imamura T, Fujita K, Tagawa K, Ikura T, Chen X, Homma H, Tamura T, Mao Y, Taniguchi JB, Motoki K, Nakabayashi M, Ito N, Yamada K, Tomii K, Okano H, Kaye J, Finkbeiner S, Okazawa H.

Sci Rep. 2016 Sep 22;6:33861. doi: 10.1038/srep33861.

45.

HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease.

Fujita K, Motoki K, Tagawa K, Chen X, Hama H, Nakajima K, Homma H, Tamura T, Watanabe H, Katsuno M, Matsumi C, Kajikawa M, Saito T, Saido T, Sobue G, Miyawaki A, Okazawa H.

Sci Rep. 2016 Aug 25;6:31895. doi: 10.1038/srep31895.

46.

Oxytocin efficacy is modulated by dosage and oxytocin receptor genotype in young adults with high-functioning autism: a 24-week randomized clinical trial.

Kosaka H, Okamoto Y, Munesue T, Yamasue H, Inohara K, Fujioka T, Anme T, Orisaka M, Ishitobi M, Jung M, Fujisawa TX, Tanaka S, Arai S, Asano M, Saito DN, Sadato N, Tomoda A, Omori M, Sato M, Okazawa H, Higashida H, Wada Y.

Transl Psychiatry. 2016 Aug 23;6(8):e872. doi: 10.1038/tp.2016.152.

47.

Allosteric modulation of the binding affinity between PQBP1 and the spliceosomal protein U5-15kD.

Mizuguchi M, Obita T, Kajiyama A, Kozakai Y, Nakai T, Nabeshima Y, Okazawa H.

FEBS Lett. 2016 Jul;590(14):2221-31. doi: 10.1002/1873-3468.12256. Epub 2016 Jun 28.

48.

Impaired myocardial microcirculation in the flow-glucose metabolism mismatch regions in revascularized acute myocardial infarction.

Fukuoka Y, Nakano A, Tama N, Hasegawa K, Ikeda H, Morishita T, Ishida K, Kaseno K, Amaya N, Uzui H, Okazawa H, Tada H.

J Nucl Cardiol. 2017 Oct;24(5):1641-1650. doi: 10.1007/s12350-016-0526-z. Epub 2016 Jun 14.

PMID:
27301963
49.

Arterial Transit Time Mapping Obtained by Pulsed Continuous 3D ASL Imaging with Multiple Post-Label Delay Acquisitions: Comparative Study with PET-CBF in Patients with Chronic Occlusive Cerebrovascular Disease.

Tsujikawa T, Kimura H, Matsuda T, Fujiwara Y, Isozaki M, Kikuta K, Okazawa H.

PLoS One. 2016 Jun 8;11(6):e0156005. doi: 10.1371/journal.pone.0156005. eCollection 2016. Erratum in: PLoS One. 2016;11(7):e0159894.

50.

Assessment of the Tumor Redox Status in Head and Neck Cancer by 62Cu-ATSM PET.

Tsujikawa T, Asahi S, Oh M, Sato Y, Narita N, Makino A, Mori T, Kiyono Y, Tsuchida T, Kimura H, Fujieda S, Okazawa H.

PLoS One. 2016 May 17;11(5):e0155635. doi: 10.1371/journal.pone.0155635. eCollection 2016.

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