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On-Site Computed Tomography-Derived Fractional Flow Reserve Using a Machine-Learning Algorithm - Clinical Effectiveness in a Retrospective Multicenter Cohort.

Kurata A, Fukuyama N, Hirai K, Kawaguchi N, Tanabe Y, Okayama H, Shigemi S, Watanabe K, Uetani T, Ikeda S, Inaba S, Kido T, Itoh T, Mochizuki T.

Circ J. 2019 Jun 8. doi: 10.1253/circj.CJ-19-0163. [Epub ahead of print]


Phospho‑STAT1 expression as a potential biomarker for anti‑PD‑1/anti‑PD‑L1 immunotherapy for breast cancer.

Nakayama Y, Mimura K, Tamaki T, Shiraishi K, Kua LF, Koh V, Ohmori M, Kimura A, Inoue S, Okayama H, Suzuki Y, Nakazawa T, Ichikawa D, Kono K.

Int J Oncol. 2019 Jun;54(6):2030-2038. doi: 10.3892/ijo.2019.4779. Epub 2019 Apr 10.


Prognostic role of ARID1A negative expression in gastric cancer.

Ashizawa M, Saito M, Min AKT, Ujiie D, Saito K, Sato T, Kikuchi T, Okayama H, Fujita S, Endo H, Sakamoto W, Momma T, Ohki S, Goto A, Kono K.

Sci Rep. 2019 May 1;9(1):6769. doi: 10.1038/s41598-019-43293-5.


Assessment of pulmonary congestion is of prime importance.

Hiasa G, Okayama H, Kazatani Y.

Heart Vessels. 2019 Apr 9. doi: 10.1007/s00380-019-01407-z. [Epub ahead of print] No abstract available.


miRNA-148a-3p Regulates Immunosuppression in DNA Mismatch Repair-Deficient Colorectal Cancer by Targeting PD-L1.

Ashizawa M, Okayama H, Ishigame T, Thar Min AK, Saito K, Ujiie D, Murakami Y, Kikuchi T, Nakayama Y, Noda M, Tada T, Endo H, Fujita S, Sakamoto W, Saito M, Saze Z, Momma T, Ohki S, Mimura K, Kono K.

Mol Cancer Res. 2019 Jun;17(6):1403-1413. doi: 10.1158/1541-7786.MCR-18-0831. Epub 2019 Mar 14.


Rapid Formation of Arrayed Cells on an Electrode with Microwells by a Scanning Electrode Based on Positive Dielectrophoresis.

Okayama H, Tomita M, Suzuki M, Yasukawa T.

Anal Sci. 2019 Jun 10;35(6):701-704. doi: 10.2116/analsci.19N002. Epub 2019 Feb 15.


[A Case of Esophageal Cancer with Cervical Lymph Node Recurrence Six Years after Complete Response to Definitive Chemoradiotherapy].

Fujita S, Ohki S, Hayase S, Ujiie D, Kikuchi T, Tada T, Hanayama H, Okayama H, Sakamoto W, Endo H, Saito M, Gonda K, Saze Z, Momma T, Kono K.

Gan To Kagaku Ryoho. 2018 Dec;45(13):1821-1823. Japanese.


Effects of wearing supportive underwear versus pelvic floor muscle training or no treatment in women with symptoms of stress urinary incontinence: an assessor-blinded randomized control trial.

Okayama H, Ninomiya S, Naito K, Endo Y, Morikawa S.

Int Urogynecol J. 2019 Jan 9. doi: 10.1007/s00192-018-03855-z. [Epub ahead of print]


Aberrant glycosylation in colorectal cancer with genomic and epigenomic alterations.

Okayama H, Noda M, Kono K.

Oncotarget. 2018 Nov 2;9(86):35609-35610. doi: 10.18632/oncotarget.26292. eCollection 2018 Nov 2. No abstract available.


[A Case of Rectal Colon Cancer with Paraneoplastic Cerebellar Degeneration].

Gonda K, Kikuchi T, Shibata M, Hatakeyama Y, Tachiya Y, Rokkaku Y, Endo H, Fujita S, Sakamoto W, Hayase S, Okayama H, Hanayama H, Tada T, Nirei A, Ujiie D, Yamada R, Saze Z, Momma T, Ohki S, Kono K.

Gan To Kagaku Ryoho. 2018 Oct;45(10):1510-1512. Japanese.


A unique case of ST-elevation myocardial infarction related to very late stent thrombosis.

Takahashi T, Okayama H, Hiasa G, Kazatani Y.

J Cardiol Cases. 2017 Oct 13;17(2):63-67. doi: 10.1016/j.jccase.2017.09.008. eCollection 2018 Feb.


[Simultaneous Transapical Transcatheter Aortic Valve Implantation and Coronary Artery Bypass Grafting;Report of a Case].

Yano A, Ishitoya H, Harada T, Nakayama T, Isshiki S, Sasaki H, Hiasa G, Okayama H.

Kyobu Geka. 2018 Sep;71(9):685-688. Japanese.


Prognostic impact of preoperative lymphocyte-to-monocyte ratio in patients with colorectal cancer with special reference to myeloid-derived suppressor cells.

Shimura T, Shibata M, Gonda K, Hayase S, Sakamoto W, Okayama H, Fujita S, Saito M, Momma T, Ohki S, Kono K.

Fukushima J Med Sci. 2018 Aug 29;64(2):64-72. doi: 10.5387/fms.2018-10. Epub 2018 Jul 14.


Prognostic role of FUT8 expression in relation to p53 status in stage II and III colorectal cancer.

Noda M, Okayama H, Kofunato Y, Chida S, Saito K, Tada T, Ashizawa M, Nakajima T, Aoto K, Kikuchi T, Sakamoto W, Endo H, Fujita S, Saito M, Momma T, Ohki S, Kono K.

PLoS One. 2018 Jul 5;13(7):e0200315. doi: 10.1371/journal.pone.0200315. eCollection 2018.


Epithelial-mesenchymal transition-converted tumor cells can induce T-cell apoptosis through upregulation of programmed death ligand 1 expression in esophageal squamous cell carcinoma.

Thar Min AK, Okayama H, Saito M, Ashizawa M, Aoto K, Nakajima T, Saito K, Hayase S, Sakamoto W, Tada T, Hanayama H, Saze Z, Momma T, Ohki S, Sato Y, Motoyama S, Mimura K, Kono K.

Cancer Med. 2018 May 31. doi: 10.1002/cam4.1564. [Epub ahead of print]


Glycosyltransferase Gene Expression Identifies a Poor Prognostic Colorectal Cancer Subtype Associated with Mismatch Repair Deficiency and Incomplete Glycan Synthesis.

Noda M, Okayama H, Tachibana K, Sakamoto W, Saito K, Thar Min AK, Ashizawa M, Nakajima T, Aoto K, Momma T, Katakura K, Ohki S, Kono K.

Clin Cancer Res. 2018 Sep 15;24(18):4468-4481. doi: 10.1158/1078-0432.CCR-17-3533. Epub 2018 May 29.


Serum transthyretin level is associated with prognosis of patients with gastric cancer.

Shimura T, Shibata M, Gonda K, Okayama H, Saito M, Momma T, Ohki S, Kono K.

J Surg Res. 2018 Jul;227:145-150. doi: 10.1016/j.jss.2018.02.035. Epub 2018 Mar 15.


Augmentation of antibody-dependent cellular cytotoxicity with defucosylated monoclonal antibodies in patients with GI-tract cancer.

Nakajima T, Okayama H, Ashizawa M, Noda M, Aoto K, Saito M, Monma T, Ohki S, Shibata M, Takenoshita S, Kono K.

Oncol Lett. 2018 Feb;15(2):2604-2610. doi: 10.3892/ol.2017.7556. Epub 2017 Dec 8.


Silicon optical filter with transmission peaks in wide stopband obtained by anti-symmetric photonic crystal with defect in multimode waveguides.

Mendez-Astudillo M, Okayama H, Nakajima H.

Opt Express. 2018 Jan 22;26(2):1841-1850. doi: 10.1364/OE.26.001841.


Beneficial effects of adaptive servo-ventilation therapy on readmission and medical costs in patients with chronic heart failure.

Hiasa G, Okayama H, Hosokawa S, Kosaki T, Kawamura G, Shigematsu T, Takahashi T, Kawada Y, Yamada T, Matsuoka H, Saito M, Sumimoto T, Kazatani Y.

Heart Vessels. 2018 Aug;33(8):859-865. doi: 10.1007/s00380-018-1124-6. Epub 2018 Jan 22.


L-type amino acid transporter 1 expression is upregulated and associated with cellular proliferation in colorectal cancer.

Hayase S, Kumamoto K, Saito K, Kofunato Y, Sato Y, Okayama H, Miyamoto K, Ohki S, Takenoshita S.

Oncol Lett. 2017 Dec;14(6):7410-7416. doi: 10.3892/ol.2017.7148. Epub 2017 Oct 6.


Isolated Left Atrial Infective Mural Endocarditis.

Hosokawa S, Okayama H, Hiasa G, Kawamura G, Shigematsu T, Takahashi T, Kawada Y, Yamada T, Matsuoka H, Kazatani Y.

Intern Med. 2018 Apr 1;57(7):957-960. doi: 10.2169/internalmedicine.9559-17. Epub 2017 Dec 8. Review.


Immunogenic tumor cell death induced by chemotherapy in patients with breast cancer and esophageal squamous cell carcinoma.

Aoto K, Mimura K, Okayama H, Saito M, Chida S, Noda M, Nakajima T, Saito K, Abe N, Ohki S, Ohtake T, Takenoshita S, Kono K.

Oncol Rep. 2018 Jan;39(1):151-159. doi: 10.3892/or.2017.6097. Epub 2017 Nov 14.


CDX2 is involved in microRNA-associated inflammatory carcinogenesis in gastric cancer.

Saito M, Okayama H, Saito K, Ando J, Kumamoto K, Nakamura I, Ohki S, Ishi Y, Takenoshita S.

Oncol Lett. 2017 Nov;14(5):6184-6190. doi: 10.3892/ol.2017.6956. Epub 2017 Sep 15.


Expression of circadian clock genes in human colorectal adenoma and carcinoma.

Momma T, Okayama H, Saitou M, Sugeno H, Yoshimoto N, Takebayashi Y, Ohki S, Takenoshita S.

Oncol Lett. 2017 Nov;14(5):5319-5325. doi: 10.3892/ol.2017.6876. Epub 2017 Sep 4.


[Regulation of PD-L1 by MicroRNA in Mismatch Repair Deficient-Colorectal Cancer].

Ashizawa M, Okayama H, Aung Kyi Thar Min, Noda M, Aoto K, Nakajima T, Ishigame T, Mimura K, Kono K.

Gan To Kagaku Ryoho. 2017 Oct;44(10):889-891. Japanese.


PD-L1 expression is mainly regulated by interferon gamma associated with JAK-STAT pathway in gastric cancer.

Mimura K, Teh JL, Okayama H, Shiraishi K, Kua LF, Koh V, Smoot DT, Ashktorab H, Oike T, Suzuki Y, Fazreen Z, Asuncion BR, Shabbir A, Yong WP, So J, Soong R, Kono K.

Cancer Sci. 2018 Jan;109(1):43-53. doi: 10.1111/cas.13424. Epub 2017 Nov 18.


Clinical Usefulness of Coronary Flow Reserve Ratio for the Detection of Significant Coronary Artery Disease on 13N-Ammonia Positron Emission Tomography.

Kawaguchi N, Okayama H, Kawamura G, Shigematsu T, Takahashi T, Kawada Y, Hiasa G, Yamada T, Matsuoka H, Kazatani Y, Miyagawa M, Mochizuki T.

Circ J. 2018 Jan 25;82(2):486-493. doi: 10.1253/circj.CJ-17-0745. Epub 2017 Sep 26.


Coronary artery disease incidentally detected by routine oncology 18F-fluorodeoxyglucose positron emission tomography.

Hiasa G, Okayama H, Kawaguchi N, Kazatani Y.

J Nucl Cardiol. 2018 Apr;25(2):688-690. doi: 10.1007/s12350-017-1064-z. Epub 2017 Sep 12. No abstract available.


Favorable effects of early tolvaptan administration in very elderly patients after repeat hospitalizations for acute decompensated heart failure.

Kinoshita M, Okayama H, Kosaki T, Hosokawa S, Kawamura G, Shigematsu T, Takahashi T, Kawada Y, Hiasa G, Yamada T, Matsuoka H, Kazatani Y.

Heart Vessels. 2018 Feb;33(2):163-169. doi: 10.1007/s00380-017-1048-6. Epub 2017 Sep 9.


Radiation-Induced Cardiomyopathy Incidentally Detected on Oncology 18F-Fluorodeoxyglucose Positron Emission Tomography.

Kawamura G, Okayama H, Kawaguchi N, Hosokawa S, Kosaki T, Shigematsu T, Takahashi T, Kawada Y, Hiasa G, Yamada T, Matsuoka H, Kazatani Y.

Circ J. 2018 Mar 23;82(4):1210-1212. doi: 10.1253/circj.CJ-17-0466. Epub 2017 Aug 18. No abstract available.


Silicon wire waveguide TE0/TE1 mode conversion Bragg grating with resonant cavity section.

Okayama H, Onawa Y, Shimura D, Yaegashi H, Sasaki H.

Opt Express. 2017 Jul 10;25(14):16672-16680. doi: 10.1364/OE.25.016672.


Prevalence and Risk Factors of Urinary Incontinence and Overactive Bladder in Japanese Women.

Ninomiya S, Naito K, Nakanishi K, Okayama H.

Low Urin Tract Symptoms. 2018 Sep;10(3):308-314. doi: 10.1111/luts.12185. Epub 2017 Aug 1.


Silicon waveguide polarization rotator sampled Bragg grating.

Okayama H, Onawa Y, Shimura D, Yaegashi H, Sasaki H.

Opt Lett. 2017 Jun 1;42(11):2142-2144. doi: 10.1364/OL.42.002142.


Intraperitoneal chemotherapy for gastric cancer with peritoneal disease: experience from Singapore and Japan.

Kono K, Yong WP, Okayama H, Shabbir A, Momma T, Ohki S, Takenoshita S, So J.

Gastric Cancer. 2017 Mar;20(Suppl 1):122-127. doi: 10.1007/s10120-016-0660-y. Epub 2016 Oct 20. Review.


18F-Fluorodeoxyglucose Positron Emission Tomography for the Diagnosis of Myocarditis Associated With Polymyositis.

Shigematsu T, Okayama H, Hiasa G, Kazatani Y.

Circ J. 2016 Dec 22;81(1):121-122. doi: 10.1253/circj.CJ-16-0811. Epub 2016 Oct 12. No abstract available.


Author's reply.

Kinoshita M, Okayama H.

J Cardiol. 2017 May;69(5):798. doi: 10.1016/j.jjcc.2016.09.001. Epub 2016 Sep 19. No abstract available.


Optical coherence tomography-based diagnosis in a patient with ST-elevation myocardial infarction and no obstructive coronary arteries.

Takahashi T, Okayama H, Matsuda K, Yamamoto T, Hosokawa S, Kosaki T, Kawamura G, Shigematsu T, Kinoshita M, Kawada Y, Hiasa G, Yamada T, Kazatani Y.

Int J Cardiol. 2016 Nov 15;223:146-148. doi: 10.1016/j.ijcard.2016.08.026. Epub 2016 Aug 4. No abstract available.


Beneficial effects of rapid introduction of adaptive servo-ventilation in the emergency room in patients with acute cardiogenic pulmonary edema.

Kinoshita M, Okayama H, Kawamura G, Shigematsu T, Takahashi T, Kawata Y, Hiasa G, Yamada T, Kazatani Y.

J Cardiol. 2017 Jan;69(1):308-313. doi: 10.1016/j.jjcc.2016.05.015. Epub 2016 Jun 29.


Stromal VCAN expression as a potential prognostic biomarker for disease recurrence in stage II-III colon cancer.

Chida S, Okayama H, Noda M, Saito K, Nakajima T, Aoto K, Hayase S, Momma T, Ohki S, Kono K, Takenoshita S.

Carcinogenesis. 2016 Sep;37(9):878-887. doi: 10.1093/carcin/bgw069. Epub 2016 Jun 9.


[Curative Surgery for Advanced Gastric Cancer with Extensive Lymph Node Metastasis after Long-Term Chemotherapy].

Fujita S, Monma T, Ohki S, Murakami Y, Okayama H, Yazawa T, Takawa M, Kumamoto K, Ohtake T, Kono K, Takenoshita S.

Gan To Kagaku Ryoho. 2015 Nov;42(12):1668-70. Japanese.


Contrast-enhanced ultrasound for the evaluation of acute renal infarction.

Miyoshi T, Okayama H, Hiasa G, Kawata Y, Yamada T, Kazatani Y.

J Med Ultrason (2001). 2016 Jan;43(1):141-3. doi: 10.1007/s10396-015-0655-z. Epub 2015 Aug 27.


Giant left ventricular pseudoaneurysm: a rare complication of surgical patch repair for left ventricular free wall rupture.

Takahashi T, Okayama H, Hiasa G, Kazatani Y, Sasaki H.

Eur Heart J Cardiovasc Imaging. 2016 Feb;17(2):176. doi: 10.1093/ehjci/jev315. Epub 2015 Dec 20. No abstract available.


Aortic prosthetic graft infection detected by (18)F-fluorodeoxyglucose positron emission tomography/computed tomography.

Kono T, Ogimoto A, Iio C, Fujimoto K, Fujii A, Uetani T, Nagai T, Nishimura K, Inoue K, Suzuki J, Hiasa G, Okayama H, Okura T, Miyagawa M, Mochizuki T, Izutani H, Higaki J.

Int J Cardiol. 2016 Jan 15;203:972-4. doi: 10.1016/j.ijcard.2015.11.069. Epub 2015 Nov 10. No abstract available.


A calcified amorphous tumor that developed on both sides of the atrioventricular valve annulus.

Kinoshita M, Okayama H, Kawamura G, Shigematsu T, Takahashi T, Miyoshi T, Higaki A, Hara K, Kawata Y, Hiasa G, Yamada T, Kazatani Y, Hayashi Y.

J Echocardiogr. 2015 Dec;13(4):148-50. doi: 10.1007/s12574-015-0267-z. Epub 2015 Nov 19.


Two cases of cardiac sarcoidosis diagnosed based on biopsy results of the gluteus muscle with focal uptake of 18F-fluorodeoxyglucose.

Takahashi T, Okayama H, Hiasa G, Kazatani Y.

Eur Heart J. 2016 Apr 7;37(14):1168. doi: 10.1093/eurheartj/ehv608. Epub 2015 Nov 9. No abstract available.


Polarization rotation Bragg diffraction using Si wire waveguide grating and polarization rotator.

Okayama H, Onawa Y, Shimura D, Yaegashi H, Sasaki H.

Opt Express. 2015 Jul 27;23(15):19698-704. doi: 10.1364/OE.23.019698.


Two inhibitory systems and CKIs regulate cell cycle exit of mammalian cardiomyocytes after birth.

Tane S, Okayama H, Ikenishi A, Amemiya Y, Nakayama KI, Takeuchi T.

Biochem Biophys Res Commun. 2015 Oct 16;466(2):147-54. doi: 10.1016/j.bbrc.2015.08.102. Epub 2015 Sep 9.


An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers.

Robles AI, Arai E, Mathé EA, Okayama H, Schetter AJ, Brown D, Petersen D, Bowman ED, Noro R, Welsh JA, Edelman DC, Stevenson HS, Wang Y, Tsuchiya N, Kohno T, Skaug V, Mollerup S, Haugen A, Meltzer PS, Yokota J, Kanai Y, Harris CC.

J Thorac Oncol. 2015 Jul;10(7):1037-48. doi: 10.1097/JTO.0000000000000560.

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