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Items: 7

1.

TET2 catalyzes active DNA demethylation of the Sry promoter and enhances its expression.

Okashita N, Kuroki S, Maeda R, Tachibana M.

Sci Rep. 2019 Sep 17;9(1):13462. doi: 10.1038/s41598-019-50058-7.

2.

Combined Loss of JMJD1A and JMJD1B Reveals Critical Roles for H3K9 Demethylation in the Maintenance of Embryonic Stem Cells and Early Embryogenesis.

Kuroki S, Nakai Y, Maeda R, Okashita N, Akiyoshi M, Yamaguchi Y, Kitano S, Miyachi H, Nakato R, Ichiyanagi K, Shirahige K, Kimura H, Shinkai Y, Tachibana M.

Stem Cell Reports. 2018 Apr 10;10(4):1340-1354. doi: 10.1016/j.stemcr.2018.02.002. Epub 2018 Mar 8.

3.

Rescuing the aberrant sex development of H3K9 demethylase Jmjd1a-deficient mice by modulating H3K9 methylation balance.

Kuroki S, Okashita N, Baba S, Maeda R, Miyawaki S, Yano M, Yamaguchi M, Kitano S, Miyachi H, Itoh A, Yoshida M, Tachibana M.

PLoS Genet. 2017 Sep 26;13(9):e1007034. doi: 10.1371/journal.pgen.1007034. eCollection 2017 Sep.

4.

PRDM14 Drives OCT3/4 Recruitment via Active Demethylation in the Transition from Primed to Naive Pluripotency.

Okashita N, Suwa Y, Nishimura O, Sakashita N, Kadota M, Nagamatsu G, Kawaguchi M, Kashida H, Nakajima A, Tachibana M, Seki Y.

Stem Cell Reports. 2016 Dec 13;7(6):1072-1086. doi: 10.1016/j.stemcr.2016.10.007. Epub 2016 Nov 17.

5.

PRDM14 maintains pluripotency of embryonic stem cells through TET-mediated active DNA demethylation.

Okashita N, Sakashita N, Ito K, Mitsuya A, Suwa Y, Seki Y.

Biochem Biophys Res Commun. 2015 Oct 9;466(1):138-45. doi: 10.1016/j.bbrc.2015.08.122. Epub 2015 Aug 29.

PMID:
26325469
6.

PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells.

Okashita N, Kumaki Y, Ebi K, Nishi M, Okamoto Y, Nakayama M, Hashimoto S, Nakamura T, Sugasawa K, Kojima N, Takada T, Okano M, Seki Y.

Development. 2014 Jan;141(2):269-80. doi: 10.1242/dev.099622. Epub 2013 Dec 11.

7.

A replication-dependent passive mechanism modulates DNA demethylation in mouse primordial germ cells.

Ohno R, Nakayama M, Naruse C, Okashita N, Takano O, Tachibana M, Asano M, Saitou M, Seki Y.

Development. 2013 Jul;140(14):2892-903. doi: 10.1242/dev.093229. Epub 2013 Jun 12.

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