Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 1188

1.

Ambient fine and coarse particles in Japan affect nasal and bronchial epithelial cells differently and elicit varying immune response.

Onishi T, Honda A, Tanaka M, Chowdhury PH, Okano H, Okuda T, Shishido D, Terui Y, Hasegawa S, Kameda T, Tohno S, Hayashi M, Nishita-Hara C, Hara K, Inoue K, Yasuda M, Hirano S, Takano H.

Environ Pollut. 2018 Jul 27. pii: S0269-7491(18)31005-4. doi: 10.1016/j.envpol.2018.07.103. [Epub ahead of print]

PMID:
30086990
2.

Early stage clear cell adenocarcinoma of the colon examined in detail with image-enhanced endoscopy: a case report.

Tochio T, Mukai K, Baba Y, Asakawa H, Nose K, Tsuruga S, Kumazawa H, Isono Y, Tanaka H, Matsusaki S, Sase T, Saito T, Okano H, Usui M, Watanabe G.

Clin J Gastroenterol. 2018 Jul 30. doi: 10.1007/s12328-018-0889-6. [Epub ahead of print]

PMID:
30062544
3.

HER2 Heterogeneity Is Associated with Poor Survival in HER2-Positive Breast Cancer.

Hosonaga M, Arima Y, Sampetrean O, Komura D, Koya I, Sasaki T, Sato E, Okano H, Kudoh J, Ishikawa S, Saya H, Ishikawa T.

Int J Mol Sci. 2018 Jul 24;19(8). pii: E2158. doi: 10.3390/ijms19082158.

4.

Loss of DDHD2, whose mutation causes spastic paraplegia, promotes reactive oxygen species generation and apoptosis.

Maruyama T, Baba T, Maemoto Y, Hara-Miyauchi C, Hasegawa-Ogawa M, Okano HJ, Enda Y, Matsumoto K, Arimitsu N, Nakao K, Hamamoto H, Sekimizu K, Ohto-Nakanishi T, Nakanishi H, Tokuyama T, Yanagi S, Tagaya M, Tani K.

Cell Death Dis. 2018 Jul 23;9(8):797. doi: 10.1038/s41419-018-0815-3.

5.

Gastric adenocarcinoma coexisting with a reddish semipedunculated polyp arising from Helicobacter pylori-negative normal gastric mucosa: a report of two cases.

Isono Y, Baba Y, Mukai K, Asakawa H, Nose K, Tsuruga S, Tochio T, Kumazawa H, Tanaka H, Matsusaki S, Sase T, Saito T, Okano H, Toyoda H.

Clin J Gastroenterol. 2018 Jul 18. doi: 10.1007/s12328-018-0887-8. [Epub ahead of print]

PMID:
30022297
6.

Single-cell trajectory analysis of human homogenous neurons carrying a rare RELN variant.

Arioka Y, Shishido E, Kubo H, Kushima I, Yoshimi A, Kimura H, Ishizuka K, Aleksic B, Maeda T, Ishikawa M, Kuzumaki N, Okano H, Mori D, Ozaki N.

Transl Psychiatry. 2018 Jul 19;8(1):129. doi: 10.1038/s41398-018-0177-8.

7.

PAT - Probabilistic Axon Tracking for Densely Labeled Neurons in Large 3D Micrographs.

Skibbe H, Reisert M, Nakae K, Watakabe A, Hata J, Mizukami H, Okano H, Yamamori T, Ishii S.

IEEE Trans Med Imaging. 2018 Jul 13. doi: 10.1109/TMI.2018.2855736. [Epub ahead of print]

PMID:
30010551
8.

Establishment of a human induced stem cell line (FUi002-A) from Dravet syndrome patient carrying heterozygous R1525X mutation in SCN1A gene.

Tanaka Y, Higurashi N, Shirasu N, Yasunaga S, Moreira KM, Okano H, Hirose S.

Stem Cell Res. 2018 Jun 19;31:11-15. doi: 10.1016/j.scr.2018.06.008. [Epub ahead of print]

9.

Stem cells purified from human induced pluripotent stem cell-derived neural crest-like cells promote peripheral nerve regeneration.

Kimura H, Ouchi T, Shibata S, Amemiya T, Nagoshi N, Nakagawa T, Matsumoto M, Okano H, Nakamura M, Sato K.

Sci Rep. 2018 Jul 3;8(1):10071. doi: 10.1038/s41598-018-27952-7.

10.

Japan Society of Obstetrics and Gynecology and Japan Society for Menopause and Women's Health 2017 guidelines for hormone replacement therapy.

Okano H, Higuchi T, Kurabayashi T, Makita K, Mizunuma H, Mochizuki Y, Obayashi S, Yasui T, Takamatsu K; Subcommittee for Revising the Japanese Guidelines for Hormone Replacement Therapy in the Women's Health Care Committee, Japan Society of Obstetrics and Gynecology.

J Obstet Gynaecol Res. 2018 Jun 29. doi: 10.1111/jog.13684. [Epub ahead of print]

PMID:
29957860
11.

Visualization of nerve fibers around the carotid bifurcation with use of a 9.4 Tesla microscopic magnetic resonance diffusion tensor imaging with tractography.

Saito S, Ozawa H, Fujioka M, Hikishima K, Hata J, Kurihara S, Okano HJ, Ogawa K.

Head Neck. 2018 Jun 26. doi: 10.1002/hed.25318. [Epub ahead of print]

PMID:
29947092
12.

Uterine leiomyomata: a retrospective study of correlations with hypertension and diabetes mellitus from the Japan Nurses' Health Study.

Yasui T, Hayashi K, Okano H, Kamio M, Mizunuma H, Kubota T, Lee JS, Suzuki S.

J Obstet Gynaecol. 2018 Jun 8:1-7. doi: 10.1080/01443615.2018.1451987. [Epub ahead of print]

PMID:
29884084
13.

Accurate fidelity analysis of the reverse transcriptase by a modified next-generation sequencing.

Okano H, Baba M, Hidese R, Iida K, Li T, Kojima K, Takita T, Yanagihara I, Fujiwara S, Yasukawa K.

Enzyme Microb Technol. 2018 Aug;115:81-85. doi: 10.1016/j.enzmictec.2018.05.001. Epub 2018 May 3.

PMID:
29859606
14.

Optogenetic astrocyte activation evokes BOLD fMRI response with oxygen consumption without neuronal activity modulation.

Takata N, Sugiura Y, Yoshida K, Koizumi M, Hiroshi N, Honda K, Yano R, Komaki Y, Matsui K, Suematsu M, Mimura M, Okano H, Tanaka KF.

Glia. 2018 May 30. doi: 10.1002/glia.23454. [Epub ahead of print]

PMID:
29845643
15.

Are We There Yet? How and When Specific Biotechnologies Will Improve Human Health.

O'Day E, Hosta-Rigau L, Oyarzún DA, Okano H, de Lorenzo V, von Kameke C, Alsafar H, Cao C, Chen GQ, Ji W, Roberts RJ, Ronaghi M, Yeung K, Zhang F, Lee SY.

Biotechnol J. 2018 May 24:e1800195. doi: 10.1002/biot.201800195. [Epub ahead of print] Review.

PMID:
29799175
16.

The Amelioration of Pain-Related Behavior in Mice with Chronic Spinal Cord Injury Treated with Neural Stem/Progenitor Cell Transplantation Combined with Treadmill Training.

Tashiro S, Nishimura S, Shinozaki M, Takano M, Konomi T, Tsuji O, Nagoshi N, Toyama Y, Liu M, Okano H, Nakamura M.

J Neurotrauma. 2018 Jul 23. doi: 10.1089/neu.2017.5537. [Epub ahead of print]

PMID:
29790403
17.

Rostrocaudal Areal Patterning of Human PSC-Derived Cortical Neurons by FGF8 Signaling.

Imaizumi K, Fujimori K, Ishii S, Otomo A, Hosoi Y, Miyajima H, Warita H, Aoki M, Hadano S, Akamatsu W, Okano H.

eNeuro. 2018 Apr 26;5(2). pii: ENEURO.0368-17.2018. doi: 10.1523/ENEURO.0368-17.2018. eCollection 2018 Mar-Apr.

18.

Elavl3 regulates neuronal polarity through the alternative splicing of an embryo-specific exon in AnkyrinG.

Ogawa Y, Yamaguchi J, Yano M, Uchiyama Y, Okano HJ.

Neurosci Res. 2018 Mar 31. pii: S0168-0102(18)30038-5. doi: 10.1016/j.neures.2018.03.008. [Epub ahead of print]

PMID:
29614249
19.

The power of synthetic biology for bioproduction, remediation and pollution control: The UN's Sustainable Development Goals will inevitably require the application of molecular biology and biotechnology on a global scale.

de Lorenzo V, Prather KL, Chen GQ, O'Day E, von Kameke C, Oyarzún DA, Hosta-Rigau L, Alsafar H, Cao C, Ji W, Okano H, Roberts RJ, Ronaghi M, Yeung K, Zhang F, Lee SY.

EMBO Rep. 2018 Apr;19(4). pii: e45658. doi: 10.15252/embr.201745658. Epub 2018 Mar 26. No abstract available.

20.

A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset (Callithrix jacchus).

Kurihara S, Fujioka M, Yoshida T, Koizumi M, Ogawa K, Kojima H, Okano HJ.

J Vis Exp. 2018 Feb 27;(132). doi: 10.3791/56574.

PMID:
29553522
21.

Recurrent Spindle Cell Carcinoma Shows Features of Mesenchymal Stem Cells.

Ouchi T, Morikawa S, Shibata S, Takahashi M, Yoshikawa M, Soma T, Miyashita H, Muraoka W, Kameyama K, Kawana H, Arima Y, Saya H, Okano H, Nakagawa T, Asoda S.

J Dent Res. 2018 Jul;97(7):779-786. doi: 10.1177/0022034518759278. Epub 2018 Mar 1.

PMID:
29494307
22.

Single-cell bioluminescence imaging of deep tissue in freely moving animals.

Iwano S, Sugiyama M, Hama H, Watakabe A, Hasegawa N, Kuchimaru T, Tanaka KZ, Takahashi M, Ishida Y, Hata J, Shimozono S, Namiki K, Fukano T, Kiyama M, Okano H, Kizaka-Kondoh S, McHugh TJ, Yamamori T, Hioki H, Maki S, Miyawaki A.

Science. 2018 Feb 23;359(6378):935-939. doi: 10.1126/science.aaq1067.

PMID:
29472486
23.

Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson's disease-like motor dysfunction.

Suda Y, Kuzumaki N, Sone T, Narita M, Tanaka K, Hamada Y, Iwasawa C, Shibasaki M, Maekawa A, Matsuo M, Akamatsu W, Hattori N, Okano H, Narita M.

Mol Brain. 2018 Feb 20;11(1):6. doi: 10.1186/s13041-018-0349-8.

24.

Generation of D1-1 TALEN isogenic control cell line from Dravet syndrome patient iPSCs using TALEN-mediated editing of the SCN1A gene.

Tanaka Y, Sone T, Higurashi N, Sakuma T, Suzuki S, Ishikawa M, Yamamoto T, Mitsui J, Tsuji H, Okano H, Hirose S.

Stem Cell Res. 2018 Apr;28:100-104. doi: 10.1016/j.scr.2018.01.036. Epub 2018 Feb 2.

25.

Nestin expression is differently regulated between odontoblasts and the subodontoblastic layer in mice.

Nakatomi M, Quispe-Salcedo A, Sakaguchi M, Ida-Yonemochi H, Okano H, Ohshima H.

Histochem Cell Biol. 2018 Apr;149(4):383-391. doi: 10.1007/s00418-018-1651-3. Epub 2018 Feb 14.

PMID:
29445893
26.

Slowdown of Translational Elongation in Escherichia coli under Hyperosmotic Stress.

Dai X, Zhu M, Warren M, Balakrishnan R, Okano H, Williamson JR, Fredrick K, Hwa T.

MBio. 2018 Feb 13;9(1). pii: e02375-17. doi: 10.1128/mBio.02375-17.

27.

Chromatin remodeler CHD7 regulates the stem cell identity of human neural progenitors.

Chai M, Sanosaka T, Okuno H, Zhou Z, Koya I, Banno S, Andoh-Noda T, Tabata Y, Shimamura R, Hayashi T, Ebisawa M, Sasagawa Y, Nikaido I, Okano H, Kohyama J.

Genes Dev. 2018 Jan 15;32(2):165-180. doi: 10.1101/gad.301887.117. Epub 2018 Feb 9.

28.

The Brain/MINDS 3D digital marmoset brain atlas.

Woodward A, Hashikawa T, Maeda M, Kaneko T, Hikishima K, Iriki A, Okano H, Yamaguchi Y.

Sci Data. 2018 Feb 13;5:180009. doi: 10.1038/sdata.2018.9.

29.

Elavl3 is essential for the maintenance of Purkinje neuron axons.

Ogawa Y, Kakumoto K, Yoshida T, Kuwako KI, Miyazaki T, Yamaguchi J, Konno A, Hata J, Uchiyama Y, Hirai H, Watanabe M, Darnell RB, Okano H, Okano HJ.

Sci Rep. 2018 Feb 9;8(1):2722. doi: 10.1038/s41598-018-21130-5.

30.

Ultrasound-guided identification of the cricothyroid membrane in a patient with a difficult airway: a case report.

Okano H, Uzawa K, Watanabe K, Motoyasu A, Tokumine J, Lefor AK, Yorozu T.

BMC Emerg Med. 2018 Feb 8;18(1):5. doi: 10.1186/s12873-018-0156-7.

31.

Nitrative Stress and Tau Accumulation in Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) in the Kii Peninsula, Japan.

Hata Y, Ma N, Yoneda M, Morimoto S, Okano H, Murayama S, Kawanishi S, Kuzuhara S, Kokubo Y.

Front Neurosci. 2018 Jan 22;11:751. doi: 10.3389/fnins.2017.00751. eCollection 2017.

32.

Japan Strengthens Regenerative Medicine Oversight.

Sipp D, Okano H.

Cell Stem Cell. 2018 Feb 1;22(2):153-156. doi: 10.1016/j.stem.2018.01.001.

PMID:
29395052
33.

Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice.

Takeda H, Hosoya M, Fujioka M, Saegusa C, Saeki T, Miwa T, Okano H, Minoda R.

Sci Rep. 2018 Jan 31;8(1):1941. doi: 10.1038/s41598-018-20277-5.

34.

Activation of ventral tegmental area dopaminergic neurons reverses pathological allodynia resulting from nerve injury or bone cancer.

Watanabe M, Narita M, Hamada Y, Yamashita A, Tamura H, Ikegami D, Kondo T, Shinzato T, Shimizu T, Fukuchi Y, Muto A, Okano H, Yamanaka A, Tawfik VL, Kuzumaki N, Navratilova E, Porreca F, Narita M.

Mol Pain. 2018 Jan-Dec;14:1744806918756406. doi: 10.1177/1744806918756406. Epub 2018 Jan 22.

35.

Chemical decontamination of iPS cell-derived neural cell mixtures.

Mao D, Chung XKW, Andoh-Noda T, Qin Y, Sato SI, Takemoto Y, Akamatsu W, Okano H, Uesugi M.

Chem Commun (Camb). 2018 Feb 1;54(11):1355-1358. doi: 10.1039/c7cc08686e.

PMID:
29350722
36.

Aqueous and organic extract of PM2.5 collected in different seasons and cities of Japan differently affect respiratory and immune systems.

Chowdhury PH, Okano H, Honda A, Kudou H, Kitamura G, Ito S, Ueda K, Takano H.

Environ Pollut. 2018 Apr;235:223-234. doi: 10.1016/j.envpol.2017.12.040. Epub 2018 Jan 4.

PMID:
29291522
37.

Generation of Induced Pluripotent Stem Cells and Neural Stem/Progenitor Cells from Newborns with Spina Bifida Aperta.

Bamba Y, Nonaka M, Sasaki N, Shofuda T, Kanematsu D, Suemizu H, Higuchi Y, Pooh RK, Kanemura Y, Okano H, Yamasaki M.

Asian Spine J. 2017 Dec;11(6):870-879. doi: 10.4184/asj.2017.11.6.870. Epub 2017 Dec 7.

38.

Isolation of dental pulp stem cells with high osteogenic potential.

Yasui T, Mabuchi Y, Morikawa S, Onizawa K, Akazawa C, Nakagawa T, Okano H, Matsuzaki Y.

Inflamm Regen. 2017 Apr 10;37:8. doi: 10.1186/s41232-017-0039-4. eCollection 2017. Review.

39.

CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations.

Okuno H, Renault Mihara F, Ohta S, Fukuda K, Kurosawa K, Akamatsu W, Sanosaka T, Kohyama J, Hayashi K, Nakajima K, Takahashi T, Wysocka J, Kosaki K, Okano H.

Elife. 2017 Nov 28;6. pii: e21114. doi: 10.7554/eLife.21114.

40.

Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system.

Yamanaka S, Tajiri S, Fujimoto T, Matsumoto K, Fukunaga S, Kim BS, Okano HJ, Yokoo T.

Nat Commun. 2017 Nov 23;8(1):1719. doi: 10.1038/s41467-017-01922-5.

41.

The Semaphorin 3A inhibitor SM-345431 preserves corneal nerve and epithelial integrity in a murine dry eye model.

Yamazaki R, Yamazoe K, Yoshida S, Hatou S, Inagaki E, Okano H, Tsubota K, Shimmura S.

Sci Rep. 2017 Nov 14;7(1):15584. doi: 10.1038/s41598-017-15682-1.

42.

Author Correction: Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway.

Morizawa YM, Hirayama Y, Ohno N, Shibata S, Shigetomi E, Sui Y, Nabekura J, Sato K, Okajima F, Takebayashi H, Okano H, Koizumi S.

Nat Commun. 2017 Nov 14;8(1):1598. doi: 10.1038/s41467-017-01594-1.

43.

Naive-like ESRRB+ iPSCs with the Capacity for Rapid Neural Differentiation.

Kisa F, Shiozawa S, Oda K, Yoshimatsu S, Nakamura M, Koya I, Kawai K, Suzuki S, Okano H.

Stem Cell Reports. 2017 Dec 12;9(6):1825-1838. doi: 10.1016/j.stemcr.2017.10.008. Epub 2017 Nov 9.

44.

Investigation of brain science and neurological/psychiatric disorders using genetically modified non-human primates.

Okano H, Kishi N.

Curr Opin Neurobiol. 2018 Jun;50:1-6. doi: 10.1016/j.conb.2017.10.016. Epub 2017 Nov 7. Review.

PMID:
29125958
45.

Digital gene atlas of neonate common marmoset brain.

Shimogori T, Abe A, Go Y, Hashikawa T, Kishi N, Kikuchi SS, Kita Y, Niimi K, Nishibe H, Okuno M, Saga K, Sakurai M, Sato M, Serizawa T, Suzuki S, Takahashi E, Tanaka M, Tatsumoto S, Toki M, U M, Wang Y, Windak KJ, Yamagishi H, Yamashita K, Yoda T, Yoshida AC, Yoshida C, Yoshimoto T, Okano H.

Neurosci Res. 2018 Mar;128:1-13. doi: 10.1016/j.neures.2017.10.009. Epub 2017 Oct 27.

PMID:
29111135
46.

Escape from Pluripotency via Inhibition of TGF-β/BMP and Activation of Wnt Signaling Accelerates Differentiation and Aging in hPSC Progeny Cells.

Fujimori K, Matsumoto T, Kisa F, Hattori N, Okano H, Akamatsu W.

Stem Cell Reports. 2017 Nov 14;9(5):1675-1691. doi: 10.1016/j.stemcr.2017.09.024. Epub 2017 Oct 26.

47.

High sensitive RNA detection by one-step RT-PCR using the genetically engineered variant of DNA polymerase with reverse transcriptase activity from hyperthermophilies.

Okano H, Baba M, Kawato K, Hidese R, Yanagihara I, Kojima K, Takita T, Fujiwara S, Yasukawa K.

J Biosci Bioeng. 2018 Mar;125(3):275-281. doi: 10.1016/j.jbiosc.2017.10.004.

PMID:
29100684
48.

Enteric Glial Dysfunction Evoked by Apolipoprotein E Deficiency Contributes to Delayed Gastric Emptying.

Fukuhara S, Masaoka T, Nishimura S, Nakamura M, Matsuzaki J, Tsugawa H, Miyoshi S, Mori H, Kawase S, Shibata S, Okano H, Kanai T, Suzuki H.

Dig Dis Sci. 2017 Dec;62(12):3359-3369. doi: 10.1007/s10620-017-4820-7. Epub 2017 Nov 2.

PMID:
29098550
49.

Structural Basis for the Serratia marcescens Lipase Secretion System: Crystal Structures of the Membrane Fusion Protein and Nucleotide-Binding Domain.

Murata D, Okano H, Angkawidjaja C, Akutsu M, Tanaka SI, Kitahara K, Yoshizawa T, Matsumura H, Kado Y, Mizohata E, Inoue T, Sano S, Koga Y, Kanaya S, Takano K.

Biochemistry. 2017 Nov 28;56(47):6281-6291. doi: 10.1021/acs.biochem.7b00985. Epub 2017 Nov 10.

PMID:
29094929
50.

Hepatitis E virus subtype 3f strains isolated from Japanese hepatitis patients with no history of travel to endemic areas - The origin analyzed by molecular evolution.

Nakano T, Takahashi M, Takahashi K, Nagashima S, Suzuki Y, Nishigaki Y, Tomita E, Okano H, Oya Y, Shiraki K, Takase K, Sugimoto K, Koyama J, Mizuo H, Ikezawa K, Aikawa T, Arai M, Okamoto H.

Virology. 2018 Jan 1;513:146-152. doi: 10.1016/j.virol.2017.08.008. Epub 2017 Oct 24.

PMID:
29078116

Supplemental Content

Support Center