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Items: 1 to 50 of 1285

1.

[Ropinirole Hydrochloride for ALS].

Takahashi S, Morimoto S, Fukushima K, Nakahara J, Okano H.

Brain Nerve. 2019 Nov;71(11):1279-1288. doi: 10.11477/mf.1416201438. Japanese.

PMID:
31722314
2.

Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians.

Hashimoto K, Kouno T, Ikawa T, Hayatsu N, Miyajima Y, Yabukami H, Terooatea T, Sasaki T, Suzuki T, Valentine M, Pascarella G, Okazaki Y, Suzuki H, Shin JW, Minoda A, Taniuchi I, Okano H, Arai Y, Hirose N, Carninci P.

Proc Natl Acad Sci U S A. 2019 Nov 12. pii: 201907883. doi: 10.1073/pnas.1907883116. [Epub ahead of print]

PMID:
31719197
3.

Alteration of Musashi1 Intra-cellular Distribution During Regeneration Following Gentamicin-Induced Hair Cell Loss in the Guinea Pig Crista Ampullaris.

Kinoshita M, Fujimoto C, Iwasaki S, Kashio A, Kikkawa YS, Kondo K, Okano H, Yamasoba T.

Front Cell Neurosci. 2019 Oct 25;13:481. doi: 10.3389/fncel.2019.00481. eCollection 2019.

4.

Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men.

Irie J, Inagaki E, Fujita M, Nakaya H, Mitsuishi M, Yamaguchi S, Yamashita K, Shigaki S, Ono T, Yukioka H, Okano H, Nabeshima YI, Imai SI, Yasui M, Tsubota K, Itoh H.

Endocr J. 2019 Nov 2. doi: 10.1507/endocrj.EJ19-0313. [Epub ahead of print]

5.

Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology.

Ide M, Ohnishi T, Toyoshima M, Balan S, Maekawa M, Shimamoto-Mitsuyama C, Iwayama Y, Ohba H, Watanabe A, Ishii T, Shibuya N, Kimura Y, Hisano Y, Murata Y, Hara T, Morikawa M, Hashimoto K, Nozaki Y, Toyota T, Wada Y, Tanaka Y, Kato T, Nishi A, Fujisawa S, Okano H, Itokawa M, Hirokawa N, Kunii Y, Kakita A, Yabe H, Iwamoto K, Meno K, Katagiri T, Dean B, Uchida K, Kimura H, Yoshikawa T.

EMBO Mol Med. 2019 Oct 28:e10695. doi: 10.15252/emmm.201910695. [Epub ahead of print]

6.

Single cell study of neural stem cells derived from human iPSCs reveal distinct progenitor populations with neurogenic and gliogenic potential.

Lam M, Sanosaka T, Lundin A, Imaizumi K, Etal D, Karlsson FH, Clausen M, Cairns J, Hicks R, Kohyama J, Kele M, Okano H, Falk A.

Genes Cells. 2019 Oct 25. doi: 10.1111/gtc.12731. [Epub ahead of print]

PMID:
31651061
7.

High-flow nasal cannula therapy reduced the respiratory rate and respiratory distress in a standard model simulator and in patients with hypoxemic respiratory failure.

Motoyasu A, Moriyama K, Okano H, Yorozu T.

Chron Respir Dis. 2019 Jan-Dec;16:1479973119880892. doi: 10.1177/1479973119880892.

8.

Measurement of baseline locomotion and other behavioral traits in a common marmoset model of Parkinson's disease established by a single administration regimen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: providing reference data for efficacious preclinical evaluations.

Ando K, Inoue T, Hikishima K, Komaki Y, Kawai K, Inoue R, Nishime C, Nishinaka E, Urano K, Okano H.

Behav Pharmacol. 2019 Oct 15. doi: 10.1097/FBP.0000000000000509. [Epub ahead of print]

PMID:
31625972
9.

Evolutionary Gain of Dbx1 Expression Drives Subplate Identity in the Cerebral Cortex.

Arai Y, Cwetsch AW, Coppola E, Cipriani S, Nishihara H, Kanki H, Saillour Y, Freret-Hodara B, Dutriaux A, Okada N, Okano H, Dehay C, Nardelli J, Gressens P, Shimogori T, D'Onofrio G, Pierani A.

Cell Rep. 2019 Oct 15;29(3):645-658.e5. doi: 10.1016/j.celrep.2019.09.007.

10.

Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis.

Grandjean J, Canella C, Anckaerts C, Ayrancı G, Bougacha S, Bienert T, Buehlmann D, Coletta L, Gallino D, Gass N, Garin CM, Nadkarni NA, Hübner NS, Karatas M, Komaki Y, Kreitz S, Mandino F, Mechling AE, Sato C, Sauer K, Shah D, Strobelt S, Takata N, Wank I, Wu T, Yahata N, Yeow LY, Yee Y, Aoki I, Chakravarty MM, Chang WT, Dhenain M, von Elverfeldt D, Harsan LA, Hess A, Jiang T, Keliris GA, Lerch JP, Meyer-Lindenberg A, Okano H, Rudin M, Sartorius A, Van der Linden A, Verhoye M, Weber-Fahr W, Wenderoth N, Zerbi V, Gozzi A.

Neuroimage. 2019 Oct 12;205:116278. doi: 10.1016/j.neuroimage.2019.116278. [Epub ahead of print]

11.

A combinational treatment of carotenoids decreases Aβ secretion in human neurons via β-secretase inhibition.

Sho M, Ichiyanagi N, Imaizumi K, Ishikawa M, Morimoto S, Watanabe H, Okano H.

Neurosci Res. 2019 Oct 10. pii: S0168-0102(19)30493-6. doi: 10.1016/j.neures.2019.10.006. [Epub ahead of print]

PMID:
31606373
12.

Sex-specific effects of apolipoprotein ε4 allele on mortality in very old and centenarian Japanese men.

Sasaki T, Nishimoto Y, Abe Y, Takayama M, Hirose N, Okano H, Arai Y.

J Gerontol A Biol Sci Med Sci. 2019 Oct 11. pii: glz242. doi: 10.1093/gerona/glz242. [Epub ahead of print]

PMID:
31603980
13.

Mutations in CHCHD2 cause α-synuclein aggregation.

Ikeda A, Nishioka K, Meng H, Takanashi M, Inoshita T, Shiba-Fukushima K, Li Y, Yoshino H, Mori A, Okuzumi A, Yamaguchi A, Nonaka R, Izawa N, Ishikawa KI, Saiki H, Morita M, Hasegawa M, Hasegawa K, Elahi M, Funayama M, Okano H, Akamatsu W, Imai Y, Hattori N.

Hum Mol Genet. 2019 Oct 10. pii: ddz241. doi: 10.1093/hmg/ddz241. [Epub ahead of print]

PMID:
31600778
14.

Developmental analyses of mouse embryos and adults using a non-overlapping tracing system for all three germ layers.

Serizawa T, Isotani A, Matsumura T, Nakanishi K, Nonaka S, Shibata S, Ikawa M, Okano H.

Development. 2019 Nov 4;146(21). pii: dev174938. doi: 10.1242/dev.174938.

PMID:
31597657
15.

Evaluating the efficacy of small molecules for neural differentiation of common marmoset ESCs and iPSCs.

Yoshimatsu S, Nakamura M, Nakajima M, Nemoto A, Sato T, Sasaki E, Shiozawa S, Okano H.

Neurosci Res. 2019 Oct 3. pii: S0168-0102(19)30262-7. doi: 10.1016/j.neures.2019.09.005. [Epub ahead of print]

PMID:
31586586
16.

Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs.

Nakamura M, Shiozawa S, Tsuboi D, Amano M, Watanabe H, Maeda S, Kimura T, Yoshimatsu S, Kisa F, Karch CM, Miyasaka T, Takashima A, Sahara N, Hisanaga SI, Ikeuchi T, Kaibuchi K, Okano H.

Stem Cell Reports. 2019 Oct 8;13(4):684-699. doi: 10.1016/j.stemcr.2019.08.011. Epub 2019 Sep 19.

17.

In Vitro Modeling of the Bipolar Disorder and Schizophrenia Using Patient-Derived Induced Pluripotent Stem Cells with Copy Number Variations of PCDH15 and RELN.

Ishii T, Ishikawa M, Fujimori K, Maeda T, Kushima I, Arioka Y, Mori D, Nakatake Y, Yamagata B, Nio S, Kato TA, Yang N, Wernig M, Kanba S, Mimura M, Ozaki N, Okano H.

eNeuro. 2019 Oct 17;6(5). pii: ENEURO.0403-18.2019. doi: 10.1523/ENEURO.0403-18.2019. Print 2019 Sep/Oct.

18.

Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy.

Iida M, Sahashi K, Kondo N, Nakatsuji H, Tohnai G, Tsutsumi Y, Noda S, Murakami A, Onodera K, Okada Y, Nakatochi M, Tsukagoshi Okabe Y, Shimizu S, Mizuno M, Adachi H, Okano H, Sobue G, Katsuno M.

Nat Commun. 2019 Sep 19;10(1):4262. doi: 10.1038/s41467-019-12282-7.

19.

[Ropinirole Hydrochloride, a Candidate Drug for ALS Treatment].

Takahashi S, Morimoto S, Okano H.

Brain Nerve. 2019 Sep;71(9):943-952. doi: 10.11477/mf.1416201386. Japanese.

PMID:
31506396
20.

Efficient generation of Knock-in/Knock-out marmoset embryo via CRISPR/Cas9 gene editing.

Kumita W, Sato K, Suzuki Y, Kurotaki Y, Harada T, Zhou Y, Kishi N, Sato K, Aiba A, Sakakibara Y, Feng G, Okano H, Sasaki E.

Sci Rep. 2019 Sep 3;9(1):12719. doi: 10.1038/s41598-019-49110-3.

21.

Accuracy of removable partial denture framework fabricated by casting with a 3D printed pattern and selective laser sintering.

Tasaka A, Shimizu T, Kato Y, Okano H, Ida Y, Higuchi S, Yamashita S.

J Prosthodont Res. 2019 Aug 26. pii: S1883-1958(19)30294-4. doi: 10.1016/j.jpor.2019.07.009. [Epub ahead of print]

PMID:
31466919
22.

A versatile toolbox for knock-in gene targeting based on the Multisite Gateway technology.

Yoshimatsu S, Sone T, Nakajima M, Sato T, Okochi R, Ishikawa M, Nakamura M, Sasaki E, Shiozawa S, Okano H.

PLoS One. 2019 Aug 27;14(8):e0221164. doi: 10.1371/journal.pone.0221164. eCollection 2019.

23.

atlasBREX: Automated template-derived brain extraction in animal MRI.

Lohmeier J, Kaneko T, Hamm B, Makowski MR, Okano H.

Sci Rep. 2019 Aug 21;9(1):12219. doi: 10.1038/s41598-019-48489-3.

24.

Generation of a human iPS cell line (CGMH.SLC26A4919-2) from a Pendred syndrome patient carrying SLC26A4 c.919-2A>G splice-site mutation.

Cheng YF, Chan YH, Hu CJ, Lu YC, Saeki T, Hosoya M, Saegusa C, Fujioka M, Okano H, Weng SM, Hsu CJ, Chang KH, Wu CC.

Stem Cell Res. 2019 Oct;40:101524. doi: 10.1016/j.scr.2019.101524. Epub 2019 Jul 31.

25.

In Utero Amniotic Fluid Stem Cell Therapy Protects Against Myelomeningocele via Spinal Cord Coverage and Hepatocyte Growth Factor Secretion.

Abe Y, Ochiai D, Masuda H, Sato Y, Otani T, Fukutake M, Ikenoue S, Miyakoshi K, Okano H, Tanaka M.

Stem Cells Transl Med. 2019 Nov;8(11):1170-1179. doi: 10.1002/sctm.19-0002. Epub 2019 Aug 13.

26.

Preoperative change of modified Glasgow prognostic score after stenting predicts the long-term outcomes of obstructive colorectal cancer.

Sato R, Oikawa M, Kakita T, Okada T, Abe T, Yazawa T, Tsuchiya H, Akazawa N, Sato M, Ohira T, Harada Y, Okano H, Ito K, Ohuchi N, Tsuchiya T.

Surg Today. 2019 Aug 12. doi: 10.1007/s00595-019-01862-1. [Epub ahead of print]

PMID:
31407166
27.

Ropinirole hydrochloride remedy for amyotrophic lateral sclerosis - Protocol for a randomized, double-blind, placebo-controlled, single-center, and open-label continuation phase I/IIa clinical trial (ROPALS trial).

Morimoto S, Takahashi S, Fukushima K, Saya H, Suzuki N, Aoki M, Okano H, Nakahara J.

Regen Ther. 2019 Jul 26;11:143-166. doi: 10.1016/j.reth.2019.07.002. eCollection 2019 Dec.

28.

[Modeling Familial Parkinson's Disease Using Patient-specific Induced Pluripotent Stem Cells].

Tabata Y, Okano H.

Brain Nerve. 2019 Aug;71(8):875-883. doi: 10.11477/mf.1416201368. Review. Japanese.

PMID:
31346144
29.

Relation of koniocellular layers of dorsal lateral geniculate to inferior pulvinar nuclei in common marmosets.

Huo BX, Zeater N, Lin MK, Takahashi YS, Hanada M, Nagashima J, Lee BC, Hata J, Zaheer A, Grünert U, Miller MI, Rosa MGP, Okano H, Martin PR, Mitra PP.

Eur J Neurosci. 2019 Jul 25. doi: 10.1111/ejn.14529. [Epub ahead of print]

PMID:
31344282
30.

The spontaneous clearance of hepatitis E virus (HEV) and emergence of HEV antibodies in a transfusion-transmitted chronic hepatitis E case after completion of chemotherapy for acute myeloid leukemia.

Okano H, Nakano T, Ito R, Tanaka A, Hoshi Y, Matsubayashi K, Asakawa H, Nose K, Tsuruga S, Tochio T, Kumazawa H, Isono Y, Tanaka H, Matsusaki S, Sase T, Saito T, Mukai K, Nishimura A, Kawakami K, Nagashima S, Takahashi M, Okamoto H.

Clin J Gastroenterol. 2019 Jul 24. doi: 10.1007/s12328-019-01024-3. [Epub ahead of print]

PMID:
31342463
31.

Neurite orientation dispersion and density imaging for evaluating the severity of neonatal hypoxic-ischemic encephalopathy in rats.

Ohki A, Saito S, Hata J, Okano HJ, Higuchi T, Fukuchi K.

Magn Reson Imaging. 2019 Oct;62:214-219. doi: 10.1016/j.mri.2019.07.013. Epub 2019 Jul 17.

PMID:
31325487
32.

Neuroscience Research Using Non-human Primate Models and Genome Editing.

Kishi N, Okano H.

In: Jaenisch R, Zhang F, Gage F, editors. Genome Editing in Neurosciences [Internet]. Cham (CH): Springer; 2017.
2017 Sep 15.

33.

The adeno-associated virus rh10 vector is an effective gene transfer system for chronic spinal cord injury.

Hoshino Y, Nishide K, Nagoshi N, Shibata S, Moritoki N, Kojima K, Tsuji O, Matsumoto M, Kohyama J, Nakamura M, Okano H.

Sci Rep. 2019 Jul 8;9(1):9844. doi: 10.1038/s41598-019-46069-z.

34.

Comparison of inner ear drug availability of combined treatment with systemic or local drug injections alone.

Li Y, Kanzaki S, Shibata S, Nakamura M, Ozaki M, Okano H, Ogawa K.

Neurosci Res. 2019 Jul 3. pii: S0168-0102(19)30250-0. doi: 10.1016/j.neures.2019.07.001. [Epub ahead of print]

PMID:
31278973
35.

Dual usage of a stage-specific fluorescent reporter system based on a helper-dependent adenoviral vector to visualize osteogenic differentiation.

Sone T, Shin M, Ouchi T, Sasanuma H, Miyamoto A, Ohte S, Tsukamoto S, Nakanishi M, Okano H, Katagiri T, Mitani K.

Sci Rep. 2019 Jul 4;9(1):9705. doi: 10.1038/s41598-019-46105-y.

36.

Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons.

Akiyama T, Suzuki N, Ishikawa M, Fujimori K, Sone T, Kawada J, Funayama R, Fujishima F, Mitsuzawa S, Ikeda K, Ono H, Shijo T, Osana S, Shirota M, Nakagawa T, Kitajima Y, Nishiyama A, Izumi R, Morimoto S, Okada Y, Kamei T, Nishida M, Nogami M, Kaneda S, Ikeuchi Y, Mitsuhashi H, Nakayama K, Fujii T, Warita H, Okano H, Aoki M.

EBioMedicine. 2019 Jul;45:362-378. doi: 10.1016/j.ebiom.2019.06.013. Epub 2019 Jun 29.

37.

Cell therapy for spinal cord injury using induced pluripotent stem cells.

Nagoshi N, Tsuji O, Nakamura M, Okano H.

Regen Ther. 2019 Jun 13;11:75-80. doi: 10.1016/j.reth.2019.05.006. eCollection 2019 Dec. Review.

38.

Anatomical and Surgical Evaluation of the Common Marmoset as an Animal Model in Hearing Research.

Kurihara S, Fujioka M, Hata J, Yoshida T, Hirabayashi M, Yamamoto Y, Ogawa K, Kojima H, Okano HJ.

Front Neuroanat. 2019 Jun 6;13:60. doi: 10.3389/fnana.2019.00060. eCollection 2019.

39.

Extracellular α-synuclein enters dopaminergic cells by modulating flotillin-1-assisted dopamine transporter endocytosis.

Kobayashi J, Hasegawa T, Sugeno N, Yoshida S, Akiyama T, Fujimori K, Hatakeyama H, Miki Y, Tomiyama A, Kawata Y, Fukuda M, Kawahata I, Yamakuni T, Ezura M, Kikuchi A, Baba T, Takeda A, Kanzaki M, Wakabayashi K, Okano H, Aoki M.

FASEB J. 2019 Sep;33(9):10240-10256. doi: 10.1096/fj.201802051R. Epub 2019 Jun 18.

PMID:
31211923
40.

Degradation of Extracellular Matrix by Matrix Metalloproteinase 2 Is Essential for the Establishment of the Blood-Brain Barrier in Drosophila.

Kanda H, Shimamura R, Koizumi-Kitajima M, Okano H.

iScience. 2019 Jun 28;16:218-229. doi: 10.1016/j.isci.2019.05.027. Epub 2019 May 27.

41.

Establishment of induced pluripotent stem cells from common marmoset fibroblasts by RNA-based reprogramming.

Nakajima M, Yoshimatsu S, Sato T, Nakamura M, Okahara J, Sasaki E, Shiozawa S, Okano H.

Biochem Biophys Res Commun. 2019 Aug 6;515(4):593-599. doi: 10.1016/j.bbrc.2019.05.175. Epub 2019 Jun 6.

PMID:
31178141
42.

Tau isoform expression and phosphorylation in marmoset brains.

Sharma G, Huo A, Kimura T, Shiozawa S, Kobayashi R, Sahara N, Ishibashi M, Ishigaki S, Saito T, Ando K, Murayama S, Hasegawa M, Sobue G, Okano H, Hisanaga SI.

J Biol Chem. 2019 Jul 26;294(30):11433-11444. doi: 10.1074/jbc.RA119.008415. Epub 2019 Jun 5.

PMID:
31171723
43.

Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease.

Kuzumaki N, Suda Y, Iwasawa C, Narita M, Sone T, Watanabe M, Maekawa A, Matsumoto T, Akamatsu W, Igarashi K, Tamura H, Takeshima H, Tawfik VL, Ushijima T, Hattori N, Okano H, Narita M.

Brain. 2019 Jun 1;142(6):1675-1689. doi: 10.1093/brain/awz084.

PMID:
31135049
44.

Large-Area Fluorescence and Electron Microscopic Correlative Imaging With Multibeam Scanning Electron Microscopy.

Shibata S, Iseda T, Mitsuhashi T, Oka A, Shindo T, Moritoki N, Nagai T, Otsubo S, Inoue T, Sasaki E, Akazawa C, Takahashi T, Schalek R, Lichtman JW, Okano H.

Front Neural Circuits. 2019 May 8;13:29. doi: 10.3389/fncir.2019.00029. eCollection 2019.

45.

Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling.

Kase Y, Otsu K, Shimazaki T, Okano H.

Stem Cell Reports. 2019 Jun 11;12(6):1313-1328. doi: 10.1016/j.stemcr.2019.04.010. Epub 2019 May 9.

46.

In vivo regeneration of interspecies chimeric kidneys using a nephron progenitor cell replacement system.

Fujimoto T, Yamanaka S, Tajiri S, Takamura T, Saito Y, Matsumoto K, Takase K, Fukunaga S, Okano HJ, Yokoo T.

Sci Rep. 2019 May 6;9(1):6965. doi: 10.1038/s41598-019-43482-2.

47.

Visualization of spatiotemporal dynamics of human glioma stem cell invasion.

Tamura R, Miyoshi H, Sampetrean O, Shinozaki M, Morimoto Y, Iwasawa C, Fukaya R, Mine Y, Masuda H, Maruyama T, Narita M, Saya H, Yoshida K, Okano H, Toda M.

Mol Brain. 2019 May 6;12(1):45. doi: 10.1186/s13041-019-0462-3.

48.

Changing clinical and molecular characteristics of hepatitis E virus infection in Mie Prefecture, Japan: Disappearance of indigenous subtype 3e strains.

Nakano T, Okano H, Takahashi M, Nagashima S, Shiraki K, Oya Y, Inoue H, Ohmori S, Tsukimoto M, Ishida S, Fujimoto S, Kobayashi M, Yamawaki M, Kumagai M, Ninomiya J, Maegawa T, Kojima Y, Araki J, Hamaoka S, Horiike S, Yoshimura H, Takeuchi K, Itoh K, Akachi S, Uraki S, Yamamoto N, Ogura S, Sugimoto K, Yoshikawa K, Hasegawa H, Iwasa M, Takei Y, Okamoto H.

Hepatol Res. 2019 Sep;49(9):1003-1014. doi: 10.1111/hepr.13357. Epub 2019 Jun 7.

PMID:
31026368
49.

Semi-supervised deep learning of brain tissue segmentation.

Ito R, Nakae K, Hata J, Okano H, Ishii S.

Neural Netw. 2019 Aug;116:25-34. doi: 10.1016/j.neunet.2019.03.014. Epub 2019 Apr 1.

PMID:
30986724
50.

Noninvasive technique to evaluate the muscle fiber characteristics using q-space imaging.

Hata J, Nakashima D, Tsuji O, Fujiyoshi K, Yasutake K, Sera Y, Komaki Y, Hikishima K, Nagura T, Matsumoto M, Okano H, Nakamura M.

PLoS One. 2019 Apr 4;14(4):e0214805. doi: 10.1371/journal.pone.0214805. eCollection 2019.

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