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Items: 1 to 50 of 1228

1.

Chronic Implantation of Whole-cortical Electrocorticographic Array in the Common Marmoset.

Komatsu M, Kaneko T, Okano H, Ichinohe N.

J Vis Exp. 2019 Feb 1;(144). doi: 10.3791/58980.

PMID:
30774127
2.

Increased Cytotoxicity of Herpes Simplex Virus Thymidine Kinase Expression in Human Induced Pluripotent Stem Cells.

Iwasawa C, Tamura R, Sugiura Y, Suzuki S, Kuzumaki N, Narita M, Suematsu M, Nakamura M, Yoshida K, Toda M, Okano H, Miyoshi H.

Int J Mol Sci. 2019 Feb 14;20(4). pii: E810. doi: 10.3390/ijms20040810.

3.

Neuroethical Issues of the Brain/MINDS Project of Japan.

Sadato N, Morita K, Kasai K, Fukushi T, Nakamura K, Nakazawa E, Okano H, Okabe S.

Neuron. 2019 Feb 6;101(3):385-389. doi: 10.1016/j.neuron.2019.01.006.

4.

Robust and efficient knock-in in embryonic stem cells and early-stage embryos of the common marmoset using the CRISPR-Cas9 system.

Yoshimatsu S, Okahara J, Sone T, Takeda Y, Nakamura M, Sasaki E, Kishi N, Shiozawa S, Okano H.

Sci Rep. 2019 Feb 6;9(1):1528. doi: 10.1038/s41598-018-37990-w.

5.

MR Imaging Properties of ex vivo Common Marmoset Brain after Formaldehyde Fixation.

Haga Y, Hata J, Uematsu A, Seki F, Komaki Y, Mizumura M, Nishio M, Kaneko T, Kishi N, Okano H, Furukawa A.

Magn Reson Med Sci. 2019 Feb 7. doi: 10.2463/mrms.mp.2018-0086. [Epub ahead of print]

6.

A high-throughput neurohistological pipeline for brain-wide mesoscale connectivity mapping of the common marmoset.

Lin MK, Takahashi YS, Huo BX, Hanada M, Nagashima J, Hata J, Tolpygo AS, Ram K, Lee BC, Miller MI, Rosa MG, Sasaki E, Iriki A, Okano H, Mitra P.

Elife. 2019 Feb 5;8. pii: e40042. doi: 10.7554/eLife.40042. [Epub ahead of print]

7.

Induced Pluripotent Stem Cells Reprogrammed with Three Inhibitors Show Accelerated Differentiation Potentials with High Levels of 2-Cell Stage Marker Expression.

Nishihara K, Shiga T, Nakamura E, Akiyama T, Sasaki T, Suzuki S, Ko MSH, Tada N, Okano H, Akamatsu W.

Stem Cell Reports. 2019 Feb 12;12(2):305-318. doi: 10.1016/j.stemcr.2018.12.018. Epub 2019 Jan 31.

8.

Guidelines for office gynecology in Japan: Japan Society of Obstetrics and Gynecology (JSOG) and Japan Association of Obstetricians and Gynecologists (JAOG) 2017 edition.

Kawaguchi R, Matsumoto K, Akira S, Ishitani K, Iwasaku K, Ueda Y, Okagaki R, Okano H, Oki T, Koga K, Kido M, Kurabayashi T, Kuribayashi Y, Sato Y, Shiina K, Takai Y, Tanimura S, Chaki O, Terauchi M, Todo Y, Noguchi Y, Nose-Ogura S, Baba T, Hirasawa A, Fujii T, Fujii T, Maruyama T, Miyagi E, Yanagida K, Yoshino O, Iwashita M, Maeda T, Minegishi T, Kobayashi H.

J Obstet Gynaecol Res. 2019 Jan 24. doi: 10.1111/jog.13831. [Epub ahead of print]

PMID:
30675969
9.

Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations.

Iwasawa C, Kuzumaki N, Suda Y, Kagawa R, Oka Y, Hattori N, Okano H, Narita M.

Mol Brain. 2019 Jan 18;12(1):5. doi: 10.1186/s13041-019-0426-7.

10.

Hepatic Injury without Granulomatous Formation Associated with Intravesical Bacillus Calmette-Guérin Therapy.

Okano H, Asakawa H, Nose K, Tsuruga S, Tochio T, Kumazawa H, Isono Y, Tanaka H, Matsusaki S, Sase T, Saito T, Mukai K, Nishimura A, Usui M, Baba Y, Murata T.

Intern Med. 2019 Jan 10. doi: 10.2169/internalmedicine.2073-18. [Epub ahead of print]

11.

Estimating the concentration of therapeutic range using disease-specific iPS cells: Low-dose rapamycin therapy for Pendred syndrome.

Hosoya M, Saeki T, Saegusa C, Matsunaga T, Okano H, Fujioka M, Ogawa K.

Regen Ther. 2018 Dec 17;10:54-63. doi: 10.1016/j.reth.2018.11.001. eCollection 2019 Jun.

12.

LOTUS Inhibits Neuronal Apoptosis and Promotes Tract Regeneration in Contusive Spinal Cord Injury Model Mice.

Ito S, Nagoshi N, Tsuji O, Shibata S, Shinozaki M, Kawabata S, Kojima K, Yasutake K, Hirokawa T, Matsumoto M, Takei K, Nakamura M, Okano H.

eNeuro. 2018 Dec 14;5(5). pii: ENEURO.0303-18.2018. doi: 10.1523/ENEURO.0303-18.2018. eCollection 2018 Sep-Oct.

13.

Treatment with a Gamma-Secretase Inhibitor Promotes Functional Recovery in Human iPSC- Derived Transplants for Chronic Spinal Cord Injury.

Okubo T, Nagoshi N, Kohyama J, Tsuji O, Shinozaki M, Shibata S, Kase Y, Matsumoto M, Nakamura M, Okano H.

Stem Cell Reports. 2018 Dec 11;11(6):1416-1432. doi: 10.1016/j.stemcr.2018.10.022. Epub 2018 Nov 29.

14.

Selective Ablation of Tumorigenic Cells Following Human Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cell Transplantation in Spinal Cord Injury.

Kojima K, Miyoshi H, Nagoshi N, Kohyama J, Itakura G, Kawabata S, Ozaki M, Iida T, Sugai K, Ito S, Fukuzawa R, Yasutake K, Renault-Mihara F, Shibata S, Matsumoto M, Nakamura M, Okano H.

Stem Cells Transl Med. 2018 Nov 28. doi: 10.1002/sctm.18-0096. [Epub ahead of print]

15.

Subcutaneous Heparin Therapy for Patients with Cancer-Associated Stroke.

Kawano H, Honda Y, Amano T, Okano H, Suzuki R, Torii M, Unno Y, Shiokawa Y, Hirano T.

J Stroke Cerebrovasc Dis. 2019 Feb;28(2):399-404. doi: 10.1016/j.jstrokecerebrovasdis.2018.10.012. Epub 2018 Nov 5.

PMID:
30409745
16.

Concise Review: Laying the Groundwork for a First-In-Human Study of an Induced Pluripotent Stem Cell-Based Intervention for Spinal Cord Injury.

Tsuji O, Sugai K, Yamaguchi R, Tashiro S, Nagoshi N, Kohyama J, Iida T, Ohkubo T, Itakura G, Isoda M, Shinozaki M, Fujiyoshi K, Kanemura Y, Yamanaka S, Nakamura M, Okano H.

Stem Cells. 2019 Jan;37(1):6-13. doi: 10.1002/stem.2926. Epub 2018 Nov 12. Review.

PMID:
30371964
17.

The Japan Monkey Centre Primates Brain Imaging Repository for comparative neuroscience: an archive of digital records including records for endangered species.

Sakai T, Hata J, Ohta H, Shintaku Y, Kimura N, Ogawa Y, Sogabe K, Mori S, Okano HJ, Hamada Y, Shibata S, Okano H, Oishi K.

Primates. 2018 Nov;59(6):553-570. doi: 10.1007/s10329-018-0694-3. Epub 2018 Oct 24.

PMID:
30357587
18.

Astrocyte-Derived Exosomes Treated With a Semaphorin 3A Inhibitor Enhance Stroke Recovery via Prostaglandin D2 Synthase.

Hira K, Ueno Y, Tanaka R, Miyamoto N, Yamashiro K, Inaba T, Urabe T, Okano H, Hattori N.

Stroke. 2018 Oct;49(10):2483-2494. doi: 10.1161/STROKEAHA.118.021272.

PMID:
30355116
19.

T-type Calcium Channels Determine the Vulnerability of Dopaminergic Neurons to Mitochondrial Stress in Familial Parkinson Disease.

Tabata Y, Imaizumi Y, Sugawara M, Andoh-Noda T, Banno S, Chai M, Sone T, Yamazaki K, Ito M, Tsukahara K, Saya H, Hattori N, Kohyama J, Okano H.

Stem Cell Reports. 2018 Nov 13;11(5):1171-1184. doi: 10.1016/j.stemcr.2018.09.006. Epub 2018 Oct 18.

20.

Versatile Roles of LKB1 Kinase Signaling in Neural Development and Homeostasis.

Kuwako KI, Okano H.

Front Mol Neurosci. 2018 Oct 2;11:354. doi: 10.3389/fnmol.2018.00354. eCollection 2018.

21.

Continuous production of d-lactic acid from cellobiose in cell recycle fermentation using β-glucosidase-displaying Escherichia coli.

Aso Y, Tsubaki M, Dang Long BH, Murakami R, Nagata K, Okano H, Phuong Dung NT, Ohara H.

J Biosci Bioeng. 2018 Oct 10. pii: S1389-1723(18)30673-X. doi: 10.1016/j.jbiosc.2018.09.011. [Epub ahead of print]

PMID:
30316699
22.

Regenerative potential of induced pluripotent stem cells derived from patients undergoing haemodialysis in kidney regeneration.

Tajiri S, Yamanaka S, Fujimoto T, Matsumoto K, Taguchi A, Nishinakamura R, Okano HJ, Yokoo T.

Sci Rep. 2018 Oct 8;8(1):14919. doi: 10.1038/s41598-018-33256-7.

23.

Unidirectional monosynaptic connections from auditory areas to the primary visual cortex in the marmoset monkey.

Majka P, Rosa MGP, Bai S, Chan JM, Huo BX, Jermakow N, Lin MK, Takahashi YS, Wolkowicz IH, Worthy KH, Rajan R, Reser DH, Wójcik DK, Okano H, Mitra PP.

Brain Struct Funct. 2019 Jan;224(1):111-131. doi: 10.1007/s00429-018-1764-4. Epub 2018 Oct 4.

PMID:
30288557
24.

Semiquantitative Evaluation of Muscle Repair by Diffusion Tensor Imaging in Mice.

Hata J, Mizuno S, Haga Y, Shimoda M, Kanai Y, Chiba K, Okano H, Nakamura M, Horiuchi K.

JBMR Plus. 2018 Mar 5;2(4):227-234. doi: 10.1002/jbm4.10040. eCollection 2018 Jul.

25.

Assessing cortical plasticity after spinal cord injury by using resting-state functional magnetic resonance imaging in awake adult mice.

Matsubayashi K, Nagoshi N, Komaki Y, Kojima K, Shinozaki M, Tsuji O, Iwanami A, Ishihara R, Takata N, Matsumoto M, Mimura M, Okano H, Nakamura M.

Sci Rep. 2018 Sep 26;8(1):14406. doi: 10.1038/s41598-018-32766-8.

26.

The pathogenesis linked to coenzyme Q10 insufficiency in iPSC-derived neurons from patients with multiple-system atrophy.

Nakamoto FK, Okamoto S, Mitsui J, Sone T, Ishikawa M, Yamamoto Y, Kanegae Y, Nakatake Y, Imaizumi K, Ishiura H, Tsuji S, Okano H.

Sci Rep. 2018 Sep 21;8(1):14215. doi: 10.1038/s41598-018-32573-1.

27.

Control of directionality of chromatin folding for the inter- and intra-domain contacts at the Tfap2c-Bmp7 locus.

Tsujimura T, Takase O, Yoshikawa M, Sano E, Hayashi M, Takato T, Toyoda A, Okano H, Hishikawa K.

Epigenetics Chromatin. 2018 Sep 14;11(1):51. doi: 10.1186/s13072-018-0221-1.

28.

The LKB1-SIK Pathway Controls Dendrite Self-Avoidance in Purkinje Cells.

Kuwako KI, Okano H.

Cell Rep. 2018 Sep 11;24(11):2808-2818.e4. doi: 10.1016/j.celrep.2018.08.029.

29.

Responses to pup vocalizations in subordinate naked mole-rats are induced by estradiol ingested through coprophagy of queen's feces.

Watarai A, Arai N, Miyawaki S, Okano H, Miura K, Mogi K, Kikusui T.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9264-9269. doi: 10.1073/pnas.1720530115. Epub 2018 Aug 27.

PMID:
30150390
30.

Calcium Transient Dynamics of Neural Ensembles in the Primary Motor Cortex of Naturally Behaving Monkeys.

Kondo T, Saito R, Otaka M, Yoshino-Saito K, Yamanaka A, Yamamori T, Watakabe A, Mizukami H, Schnitzer MJ, Tanaka KF, Ushiba J, Okano H.

Cell Rep. 2018 Aug 21;24(8):2191-2195.e4. doi: 10.1016/j.celrep.2018.07.057.

31.

Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent.

Fujimori K, Ishikawa M, Otomo A, Atsuta N, Nakamura R, Akiyama T, Hadano S, Aoki M, Saya H, Sobue G, Okano H.

Nat Med. 2018 Oct;24(10):1579-1589. doi: 10.1038/s41591-018-0140-5. Epub 2018 Aug 20.

PMID:
30127392
32.

Ambient fine and coarse particles in Japan affect nasal and bronchial epithelial cells differently and elicit varying immune response.

Onishi T, Honda A, Tanaka M, Chowdhury PH, Okano H, Okuda T, Shishido D, Terui Y, Hasegawa S, Kameda T, Tohno S, Hayashi M, Nishita-Hara C, Hara K, Inoue K, Yasuda M, Hirano S, Takano H.

Environ Pollut. 2018 Nov;242(Pt B):1693-1701. doi: 10.1016/j.envpol.2018.07.103. Epub 2018 Jul 27.

PMID:
30086990
33.

Early stage clear cell adenocarcinoma of the colon examined in detail with image-enhanced endoscopy: a case report.

Tochio T, Mukai K, Baba Y, Asakawa H, Nose K, Tsuruga S, Kumazawa H, Isono Y, Tanaka H, Matsusaki S, Sase T, Saito T, Okano H, Usui M, Watanabe G.

Clin J Gastroenterol. 2018 Dec;11(6):465-469. doi: 10.1007/s12328-018-0889-6. Epub 2018 Jul 30.

PMID:
30062544
34.

HER2 Heterogeneity Is Associated with Poor Survival in HER2-Positive Breast Cancer.

Hosonaga M, Arima Y, Sampetrean O, Komura D, Koya I, Sasaki T, Sato E, Okano H, Kudoh J, Ishikawa S, Saya H, Ishikawa T.

Int J Mol Sci. 2018 Jul 24;19(8). pii: E2158. doi: 10.3390/ijms19082158.

35.

Loss of DDHD2, whose mutation causes spastic paraplegia, promotes reactive oxygen species generation and apoptosis.

Maruyama T, Baba T, Maemoto Y, Hara-Miyauchi C, Hasegawa-Ogawa M, Okano HJ, Enda Y, Matsumoto K, Arimitsu N, Nakao K, Hamamoto H, Sekimizu K, Ohto-Nakanishi T, Nakanishi H, Tokuyama T, Yanagi S, Tagaya M, Tani K.

Cell Death Dis. 2018 Jul 23;9(8):797. doi: 10.1038/s41419-018-0815-3.

36.

Gastric adenocarcinoma coexisting with a reddish semipedunculated polyp arising from Helicobacter pylori-negative normal gastric mucosa: a report of two cases.

Isono Y, Baba Y, Mukai K, Asakawa H, Nose K, Tsuruga S, Tochio T, Kumazawa H, Tanaka H, Matsusaki S, Sase T, Saito T, Okano H, Toyoda H.

Clin J Gastroenterol. 2018 Dec;11(6):481-486. doi: 10.1007/s12328-018-0887-8. Epub 2018 Jul 18.

PMID:
30022297
37.

Single-cell trajectory analysis of human homogenous neurons carrying a rare RELN variant.

Arioka Y, Shishido E, Kubo H, Kushima I, Yoshimi A, Kimura H, Ishizuka K, Aleksic B, Maeda T, Ishikawa M, Kuzumaki N, Okano H, Mori D, Ozaki N.

Transl Psychiatry. 2018 Jul 19;8(1):129. doi: 10.1038/s41398-018-0177-8.

38.

PAT-Probabilistic Axon Tracking for Densely Labeled Neurons in Large 3-D Micrographs.

Skibbe H, Reisert M, Nakae K, Watakabe A, Hata J, Mizukami H, Okano H, Yamamori T, Ishii S.

IEEE Trans Med Imaging. 2019 Jan;38(1):69-78. doi: 10.1109/TMI.2018.2855736. Epub 2018 Jul 13.

PMID:
30010551
39.

Establishment of a human induced stem cell line (FUi002-A) from Dravet syndrome patient carrying heterozygous R1525X mutation in SCN1A gene.

Tanaka Y, Higurashi N, Shirasu N, Yasunaga S, Moreira KM, Okano H, Hirose S.

Stem Cell Res. 2018 Aug;31:11-15. doi: 10.1016/j.scr.2018.06.008. Epub 2018 Jun 19.

40.

Stem cells purified from human induced pluripotent stem cell-derived neural crest-like cells promote peripheral nerve regeneration.

Kimura H, Ouchi T, Shibata S, Amemiya T, Nagoshi N, Nakagawa T, Matsumoto M, Okano H, Nakamura M, Sato K.

Sci Rep. 2018 Jul 3;8(1):10071. doi: 10.1038/s41598-018-27952-7.

41.

Japan Society of Obstetrics and Gynecology and Japan Society for Menopause and Women's Health 2017 guidelines for hormone replacement therapy.

Okano H, Higuchi T, Kurabayashi T, Makita K, Mizunuma H, Mochizuki Y, Obayashi S, Yasui T, Takamatsu K; Subcommittee for Revising the Japanese Guidelines for Hormone Replacement Therapy in the Women's Health Care Committee, Japan Society of Obstetrics and Gynecology.

J Obstet Gynaecol Res. 2018 Aug;44(8):1355-1368. doi: 10.1111/jog.13684. Epub 2018 Jun 29.

PMID:
29957860
42.

Visualization of nerve fibers around the carotid bifurcation with use of a 9.4 Tesla microscopic magnetic resonance diffusion tensor imaging with tractography.

Saito S, Ozawa H, Fujioka M, Hikishima K, Hata J, Kurihara S, Okano HJ, Ogawa K.

Head Neck. 2018 Oct;40(10):2228-2234. doi: 10.1002/hed.25318. Epub 2018 Jun 26.

43.

Uterine leiomyomata: a retrospective study of correlations with hypertension and diabetes mellitus from the Japan Nurses' Health Study.

Yasui T, Hayashi K, Okano H, Kamio M, Mizunuma H, Kubota T, Lee JS, Suzuki S.

J Obstet Gynaecol. 2018 Nov;38(8):1128-1134. doi: 10.1080/01443615.2018.1451987. Epub 2018 Jun 8.

PMID:
29884084
44.

Accurate fidelity analysis of the reverse transcriptase by a modified next-generation sequencing.

Okano H, Baba M, Hidese R, Iida K, Li T, Kojima K, Takita T, Yanagihara I, Fujiwara S, Yasukawa K.

Enzyme Microb Technol. 2018 Aug;115:81-85. doi: 10.1016/j.enzmictec.2018.05.001. Epub 2018 May 3.

PMID:
29859606
45.

Optogenetic astrocyte activation evokes BOLD fMRI response with oxygen consumption without neuronal activity modulation.

Takata N, Sugiura Y, Yoshida K, Koizumi M, Hiroshi N, Honda K, Yano R, Komaki Y, Matsui K, Suematsu M, Mimura M, Okano H, Tanaka KF.

Glia. 2018 Sep;66(9):2013-2023. doi: 10.1002/glia.23454. Epub 2018 May 30.

PMID:
29845643
46.

Are We There Yet? How and When Specific Biotechnologies Will Improve Human Health.

O'Day E, Hosta-Rigau L, Oyarzún DA, Okano H, de Lorenzo V, von Kameke C, Alsafar H, Cao C, Chen GQ, Ji W, Roberts RJ, Ronaghi M, Yeung K, Zhang F, Lee SY.

Biotechnol J. 2019 Jan;14(1):e1800195. doi: 10.1002/biot.201800195. Epub 2018 Jun 13. Review.

PMID:
29799175
47.

The Amelioration of Pain-Related Behavior in Mice with Chronic Spinal Cord Injury Treated with Neural Stem/Progenitor Cell Transplantation Combined with Treadmill Training.

Tashiro S, Nishimura S, Shinozaki M, Takano M, Konomi T, Tsuji O, Nagoshi N, Toyama Y, Liu M, Okano H, Nakamura M.

J Neurotrauma. 2018 Nov 1;35(21):2561-2571. doi: 10.1089/neu.2017.5537. Epub 2018 Jul 23.

PMID:
29790403
48.

Rostrocaudal Areal Patterning of Human PSC-Derived Cortical Neurons by FGF8 Signaling.

Imaizumi K, Fujimori K, Ishii S, Otomo A, Hosoi Y, Miyajima H, Warita H, Aoki M, Hadano S, Akamatsu W, Okano H.

eNeuro. 2018 Apr 26;5(2). pii: ENEURO.0368-17.2018. doi: 10.1523/ENEURO.0368-17.2018. eCollection 2018 Mar-Apr.

49.

Elavl3 regulates neuronal polarity through the alternative splicing of an embryo-specific exon in AnkyrinG.

Ogawa Y, Yamaguchi J, Yano M, Uchiyama Y, Okano HJ.

Neurosci Res. 2018 Oct;135:13-20. doi: 10.1016/j.neures.2018.03.008. Epub 2018 Mar 31.

PMID:
29614249
50.

The power of synthetic biology for bioproduction, remediation and pollution control: The UN's Sustainable Development Goals will inevitably require the application of molecular biology and biotechnology on a global scale.

de Lorenzo V, Prather KL, Chen GQ, O'Day E, von Kameke C, Oyarzún DA, Hosta-Rigau L, Alsafar H, Cao C, Ji W, Okano H, Roberts RJ, Ronaghi M, Yeung K, Zhang F, Lee SY.

EMBO Rep. 2018 Apr;19(4). pii: e45658. doi: 10.15252/embr.201745658. Epub 2018 Mar 26. No abstract available.

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