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Items: 1 to 50 of 1246

1.

Degradation of Extracellular Matrix by Matrix Metalloproteinase 2 Is Essential for the Establishment of the Blood-Brain Barrier in Drosophila.

Kanda H, Shimamura R, Koizumi-Kitajima M, Okano H.

iScience. 2019 May 27;16:218-229. doi: 10.1016/j.isci.2019.05.027. [Epub ahead of print]

2.

Establishment of induced pluripotent stem cells from common marmoset fibroblasts by RNA-based reprogramming.

Nakajima M, Yoshimatsu S, Sato T, Nakamura M, Okahara J, Sasaki E, Shiozawa S, Okano H.

Biochem Biophys Res Commun. 2019 Jun 6. pii: S0006-291X(19)31093-9. doi: 10.1016/j.bbrc.2019.05.175. [Epub ahead of print]

PMID:
31178141
3.

Tau isoform expression and phosphorylation in marmoset brains.

Sharma G, Huo A, Kimura T, Shiozawa S, Kobayashi R, Sahara N, Ishibashi M, Ishigaki S, Saito T, Ando K, Murayama S, Hasegawa M, Sobue G, Okano H, Hisanaga SI.

J Biol Chem. 2019 Jun 5. pii: jbc.RA119.008415. doi: 10.1074/jbc.RA119.008415. [Epub ahead of print]

4.

Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease.

Kuzumaki N, Suda Y, Iwasawa C, Narita M, Sone T, Watanabe M, Maekawa A, Matsumoto T, Akamatsu W, Igarashi K, Tamura H, Takeshima H, Tawfik VL, Ushijima T, Hattori N, Okano H, Narita M.

Brain. 2019 Jun 1;142(6):1675-1689. doi: 10.1093/brain/awz084.

PMID:
31135049
5.

Large-Area Fluorescence and Electron Microscopic Correlative Imaging With Multibeam Scanning Electron Microscopy.

Shibata S, Iseda T, Mitsuhashi T, Oka A, Shindo T, Moritoki N, Nagai T, Otsubo S, Inoue T, Sasaki E, Akazawa C, Takahashi T, Schalek R, Lichtman JW, Okano H.

Front Neural Circuits. 2019 May 8;13:29. doi: 10.3389/fncir.2019.00029. eCollection 2019.

6.

Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling.

Kase Y, Otsu K, Shimazaki T, Okano H.

Stem Cell Reports. 2019 Jun 11;12(6):1313-1328. doi: 10.1016/j.stemcr.2019.04.010. Epub 2019 May 9.

7.

In vivo regeneration of interspecies chimeric kidneys using a nephron progenitor cell replacement system.

Fujimoto T, Yamanaka S, Tajiri S, Takamura T, Saito Y, Matsumoto K, Takase K, Fukunaga S, Okano HJ, Yokoo T.

Sci Rep. 2019 May 6;9(1):6965. doi: 10.1038/s41598-019-43482-2.

8.

Visualization of spatiotemporal dynamics of human glioma stem cell invasion.

Tamura R, Miyoshi H, Sampetrean O, Shinozaki M, Morimoto Y, Iwasawa C, Fukaya R, Mine Y, Masuda H, Maruyama T, Narita M, Saya H, Yoshida K, Okano H, Toda M.

Mol Brain. 2019 May 6;12(1):45. doi: 10.1186/s13041-019-0462-3.

9.

Changing clinical and molecular characteristics of hepatitis E virus infection in Mie Prefecture, Japan: Disappearance of indigenous subtype 3e strains.

Nakano T, Okano H, Takahashi M, Nagashima S, Shiraki K, Oya Y, Inoue H, Ohmori S, Tsukimoto M, Ishida S, Fujimoto S, Kobayashi M, Yamawaki M, Kumagai M, Ninomiya J, Maegawa T, Kojima Y, Araki J, Hamaoka S, Horiike S, Yoshimura H, Takeuchi K, Itoh K, Akachi S, Uraki S, Yamamoto N, Ogura S, Sugimoto K, Yoshikawa K, Hasegawa H, Iwasa M, Takei Y, Okamoto H.

Hepatol Res. 2019 Apr 26. doi: 10.1111/hepr.13357. [Epub ahead of print]

PMID:
31026368
10.

Semi-supervised deep learning of brain tissue segmentation.

Ito R, Nakae K, Hata J, Okano H, Ishii S.

Neural Netw. 2019 Apr 1;116:25-34. doi: 10.1016/j.neunet.2019.03.014. [Epub ahead of print]

PMID:
30986724
11.

Noninvasive technique to evaluate the muscle fiber characteristics using q-space imaging.

Hata J, Nakashima D, Tsuji O, Fujiyoshi K, Yasutake K, Sera Y, Komaki Y, Hikishima K, Nagura T, Matsumoto M, Okano H, Nakamura M.

PLoS One. 2019 Apr 4;14(4):e0214805. doi: 10.1371/journal.pone.0214805. eCollection 2019.

12.

Comparison of the long-term outcomes of the self-expandable metallic stent and transanal decompression tube for obstructive colorectal cancer.

Sato R, Oikawa M, Kakita T, Okada T, Oyama A, Abe T, Yazawa T, Tsuchiya H, Akazawa N, Ohira T, Harada Y, Tanaka M, Okano H, Ito K, Tsuchiya T.

Ann Gastroenterol Surg. 2019 Jan 29;3(2):209-216. doi: 10.1002/ags3.12235. eCollection 2019 Mar.

13.

Predictable Value of Functional Independence Measure Differs between Anterior and Posterior Circulation Ischemic Strokes.

Kawano H, Johno T, Torii M, Kamiyama H, Amano T, Honda Y, Okano H, Unno Y, Yamada S, Okajima Y, Shiokawa Y, Hirano T.

Eur Neurol. 2018;80(5-6):313-320. doi: 10.1159/000499132. Epub 2019 Mar 21.

PMID:
30897587
14.

Analysis of skeletal-muscle condition after excessive loading of the lower legs by sequential magnetic resonance imaging.

Hata J, Endo K, Tsuji O, Arakawa S, Sato M, Yagi K, Fujiyoshi K, Okano H, Nakamura M.

J Orthop Sci. 2019 Mar 13. pii: S0949-2658(19)30067-3. doi: 10.1016/j.jos.2019.01.016. [Epub ahead of print]

PMID:
30878454
15.

Correlative study using structural MRI and super-resolution microscopy to detect structural alterations induced by long-term optogenetic stimulation of striatal medium spiny neurons.

Abe Y, Komaki Y, Seki F, Shibata S, Okano H, Tanaka KF.

Neurochem Int. 2019 May;125:163-174. doi: 10.1016/j.neuint.2019.02.017. Epub 2019 Feb 27.

PMID:
30825601
16.

Application of Hepatocyte Growth Factor for Acute Spinal Cord Injury: The Road from Basic Studies to Human Treatment.

Kitamura K, Nagoshi N, Tsuji O, Matsumoto M, Okano H, Nakamura M.

Int J Mol Sci. 2019 Feb 28;20(5). pii: E1054. doi: 10.3390/ijms20051054. Review.

17.

Comparative Principles for Next-Generation Neuroscience.

Miller CT, Hale ME, Okano H, Okabe S, Mitra P.

Front Behav Neurosci. 2019 Feb 5;13:12. doi: 10.3389/fnbeh.2019.00012. eCollection 2019.

18.

Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming.

Muraoka N, Nara K, Tamura F, Kojima H, Yamakawa H, Sadahiro T, Miyamoto K, Isomi M, Haginiwa S, Tani H, Kurotsu S, Osakabe R, Torii S, Shimizu S, Okano H, Sugimoto Y, Fukuda K, Ieda M.

Nat Commun. 2019 Feb 20;10(1):674. doi: 10.1038/s41467-019-08626-y.

19.

Chronic Implantation of Whole-cortical Electrocorticographic Array in the Common Marmoset.

Komatsu M, Kaneko T, Okano H, Ichinohe N.

J Vis Exp. 2019 Feb 1;(144). doi: 10.3791/58980.

PMID:
30774127
20.

Increased Cytotoxicity of Herpes Simplex Virus Thymidine Kinase Expression in Human Induced Pluripotent Stem Cells.

Iwasawa C, Tamura R, Sugiura Y, Suzuki S, Kuzumaki N, Narita M, Suematsu M, Nakamura M, Yoshida K, Toda M, Okano H, Miyoshi H.

Int J Mol Sci. 2019 Feb 14;20(4). pii: E810. doi: 10.3390/ijms20040810.

21.

Neuroethical Issues of the Brain/MINDS Project of Japan.

Sadato N, Morita K, Kasai K, Fukushi T, Nakamura K, Nakazawa E, Okano H, Okabe S.

Neuron. 2019 Feb 6;101(3):385-389. doi: 10.1016/j.neuron.2019.01.006.

22.

Robust and efficient knock-in in embryonic stem cells and early-stage embryos of the common marmoset using the CRISPR-Cas9 system.

Yoshimatsu S, Okahara J, Sone T, Takeda Y, Nakamura M, Sasaki E, Kishi N, Shiozawa S, Okano H.

Sci Rep. 2019 Feb 6;9(1):1528. doi: 10.1038/s41598-018-37990-w.

23.

MR Imaging Properties of ex vivo Common Marmoset Brain after Formaldehyde Fixation.

Haga Y, Hata J, Uematsu A, Seki F, Komaki Y, Mizumura M, Nishio M, Kaneko T, Kishi N, Okano H, Furukawa A.

Magn Reson Med Sci. 2019 Feb 7. doi: 10.2463/mrms.mp.2018-0086. [Epub ahead of print]

24.

A high-throughput neurohistological pipeline for brain-wide mesoscale connectivity mapping of the common marmoset.

Lin MK, Takahashi YS, Huo BX, Hanada M, Nagashima J, Hata J, Tolpygo AS, Ram K, Lee BC, Miller MI, Rosa MG, Sasaki E, Iriki A, Okano H, Mitra P.

Elife. 2019 Feb 5;8. pii: e40042. doi: 10.7554/eLife.40042.

25.

Induced Pluripotent Stem Cells Reprogrammed with Three Inhibitors Show Accelerated Differentiation Potentials with High Levels of 2-Cell Stage Marker Expression.

Nishihara K, Shiga T, Nakamura E, Akiyama T, Sasaki T, Suzuki S, Ko MSH, Tada N, Okano H, Akamatsu W.

Stem Cell Reports. 2019 Feb 12;12(2):305-318. doi: 10.1016/j.stemcr.2018.12.018. Epub 2019 Jan 31.

26.

Guidelines for office gynecology in Japan: Japan Society of Obstetrics and Gynecology (JSOG) and Japan Association of Obstetricians and Gynecologists (JAOG) 2017 edition.

Kawaguchi R, Matsumoto K, Akira S, Ishitani K, Iwasaku K, Ueda Y, Okagaki R, Okano H, Oki T, Koga K, Kido M, Kurabayashi T, Kuribayashi Y, Sato Y, Shiina K, Takai Y, Tanimura S, Chaki O, Terauchi M, Todo Y, Noguchi Y, Nose-Ogura S, Baba T, Hirasawa A, Fujii T, Fujii T, Maruyama T, Miyagi E, Yanagida K, Yoshino O, Iwashita M, Maeda T, Minegishi T, Kobayashi H.

J Obstet Gynaecol Res. 2019 Apr;45(4):766-786. doi: 10.1111/jog.13831. Epub 2019 Jan 24.

PMID:
30675969
27.

Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations.

Iwasawa C, Kuzumaki N, Suda Y, Kagawa R, Oka Y, Hattori N, Okano H, Narita M.

Mol Brain. 2019 Jan 18;12(1):5. doi: 10.1186/s13041-019-0426-7.

28.

Hepatic Injury without Granulomatous Formation Associated with Intravesical Bacillus Calmette-Guérin Therapy.

Okano H, Asakawa H, Nose K, Tsuruga S, Tochio T, Kumazawa H, Isono Y, Tanaka H, Matsusaki S, Sase T, Saito T, Mukai K, Nishimura A, Usui M, Baba Y, Murata T.

Intern Med. 2019 May 15;58(10):1429-1432. doi: 10.2169/internalmedicine.2073-18. Epub 2019 Jan 10.

29.

Estimating the concentration of therapeutic range using disease-specific iPS cells: Low-dose rapamycin therapy for Pendred syndrome.

Hosoya M, Saeki T, Saegusa C, Matsunaga T, Okano H, Fujioka M, Ogawa K.

Regen Ther. 2018 Dec 17;10:54-63. doi: 10.1016/j.reth.2018.11.001. eCollection 2019 Jun.

30.

LOTUS Inhibits Neuronal Apoptosis and Promotes Tract Regeneration in Contusive Spinal Cord Injury Model Mice.

Ito S, Nagoshi N, Tsuji O, Shibata S, Shinozaki M, Kawabata S, Kojima K, Yasutake K, Hirokawa T, Matsumoto M, Takei K, Nakamura M, Okano H.

eNeuro. 2018 Dec 14;5(5). pii: ENEURO.0303-18.2018. doi: 10.1523/ENEURO.0303-18.2018. eCollection 2018 Sep-Oct.

31.

Treatment with a Gamma-Secretase Inhibitor Promotes Functional Recovery in Human iPSC- Derived Transplants for Chronic Spinal Cord Injury.

Okubo T, Nagoshi N, Kohyama J, Tsuji O, Shinozaki M, Shibata S, Kase Y, Matsumoto M, Nakamura M, Okano H.

Stem Cell Reports. 2018 Dec 11;11(6):1416-1432. doi: 10.1016/j.stemcr.2018.10.022. Epub 2018 Nov 29.

32.

Selective Ablation of Tumorigenic Cells Following Human Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cell Transplantation in Spinal Cord Injury.

Kojima K, Miyoshi H, Nagoshi N, Kohyama J, Itakura G, Kawabata S, Ozaki M, Iida T, Sugai K, Ito S, Fukuzawa R, Yasutake K, Renault-Mihara F, Shibata S, Matsumoto M, Nakamura M, Okano H.

Stem Cells Transl Med. 2019 Mar;8(3):260-270. doi: 10.1002/sctm.18-0096. Epub 2018 Nov 28.

33.

Subcutaneous Heparin Therapy for Patients with Cancer-Associated Stroke.

Kawano H, Honda Y, Amano T, Okano H, Suzuki R, Torii M, Unno Y, Shiokawa Y, Hirano T.

J Stroke Cerebrovasc Dis. 2019 Feb;28(2):399-404. doi: 10.1016/j.jstrokecerebrovasdis.2018.10.012. Epub 2018 Nov 5.

PMID:
30409745
34.

Concise Review: Laying the Groundwork for a First-In-Human Study of an Induced Pluripotent Stem Cell-Based Intervention for Spinal Cord Injury.

Tsuji O, Sugai K, Yamaguchi R, Tashiro S, Nagoshi N, Kohyama J, Iida T, Ohkubo T, Itakura G, Isoda M, Shinozaki M, Fujiyoshi K, Kanemura Y, Yamanaka S, Nakamura M, Okano H.

Stem Cells. 2019 Jan;37(1):6-13. doi: 10.1002/stem.2926. Epub 2018 Nov 12. Review.

PMID:
30371964
35.

The Japan Monkey Centre Primates Brain Imaging Repository for comparative neuroscience: an archive of digital records including records for endangered species.

Sakai T, Hata J, Ohta H, Shintaku Y, Kimura N, Ogawa Y, Sogabe K, Mori S, Okano HJ, Hamada Y, Shibata S, Okano H, Oishi K.

Primates. 2018 Nov;59(6):553-570. doi: 10.1007/s10329-018-0694-3. Epub 2018 Oct 24.

PMID:
30357587
36.

Astrocyte-Derived Exosomes Treated With a Semaphorin 3A Inhibitor Enhance Stroke Recovery via Prostaglandin D2 Synthase.

Hira K, Ueno Y, Tanaka R, Miyamoto N, Yamashiro K, Inaba T, Urabe T, Okano H, Hattori N.

Stroke. 2018 Oct;49(10):2483-2494. doi: 10.1161/STROKEAHA.118.021272.

PMID:
30355116
37.

T-type Calcium Channels Determine the Vulnerability of Dopaminergic Neurons to Mitochondrial Stress in Familial Parkinson Disease.

Tabata Y, Imaizumi Y, Sugawara M, Andoh-Noda T, Banno S, Chai M, Sone T, Yamazaki K, Ito M, Tsukahara K, Saya H, Hattori N, Kohyama J, Okano H.

Stem Cell Reports. 2018 Nov 13;11(5):1171-1184. doi: 10.1016/j.stemcr.2018.09.006. Epub 2018 Oct 18.

38.

Versatile Roles of LKB1 Kinase Signaling in Neural Development and Homeostasis.

Kuwako KI, Okano H.

Front Mol Neurosci. 2018 Oct 2;11:354. doi: 10.3389/fnmol.2018.00354. eCollection 2018.

39.

Continuous production of d-lactic acid from cellobiose in cell recycle fermentation using β-glucosidase-displaying Escherichia coli.

Aso Y, Tsubaki M, Dang Long BH, Murakami R, Nagata K, Okano H, Phuong Dung NT, Ohara H.

J Biosci Bioeng. 2019 Apr;127(4):441-446. doi: 10.1016/j.jbiosc.2018.09.011. Epub 2018 Oct 11.

PMID:
30316699
40.

Regenerative potential of induced pluripotent stem cells derived from patients undergoing haemodialysis in kidney regeneration.

Tajiri S, Yamanaka S, Fujimoto T, Matsumoto K, Taguchi A, Nishinakamura R, Okano HJ, Yokoo T.

Sci Rep. 2018 Oct 8;8(1):14919. doi: 10.1038/s41598-018-33256-7.

41.

Unidirectional monosynaptic connections from auditory areas to the primary visual cortex in the marmoset monkey.

Majka P, Rosa MGP, Bai S, Chan JM, Huo BX, Jermakow N, Lin MK, Takahashi YS, Wolkowicz IH, Worthy KH, Rajan R, Reser DH, Wójcik DK, Okano H, Mitra PP.

Brain Struct Funct. 2019 Jan;224(1):111-131. doi: 10.1007/s00429-018-1764-4. Epub 2018 Oct 4.

42.

Semiquantitative Evaluation of Muscle Repair by Diffusion Tensor Imaging in Mice.

Hata J, Mizuno S, Haga Y, Shimoda M, Kanai Y, Chiba K, Okano H, Nakamura M, Horiuchi K.

JBMR Plus. 2018 Mar 5;2(4):227-234. doi: 10.1002/jbm4.10040. eCollection 2018 Jul.

43.

Assessing cortical plasticity after spinal cord injury by using resting-state functional magnetic resonance imaging in awake adult mice.

Matsubayashi K, Nagoshi N, Komaki Y, Kojima K, Shinozaki M, Tsuji O, Iwanami A, Ishihara R, Takata N, Matsumoto M, Mimura M, Okano H, Nakamura M.

Sci Rep. 2018 Sep 26;8(1):14406. doi: 10.1038/s41598-018-32766-8.

44.

The pathogenesis linked to coenzyme Q10 insufficiency in iPSC-derived neurons from patients with multiple-system atrophy.

Nakamoto FK, Okamoto S, Mitsui J, Sone T, Ishikawa M, Yamamoto Y, Kanegae Y, Nakatake Y, Imaizumi K, Ishiura H, Tsuji S, Okano H.

Sci Rep. 2018 Sep 21;8(1):14215. doi: 10.1038/s41598-018-32573-1.

45.

Control of directionality of chromatin folding for the inter- and intra-domain contacts at the Tfap2c-Bmp7 locus.

Tsujimura T, Takase O, Yoshikawa M, Sano E, Hayashi M, Takato T, Toyoda A, Okano H, Hishikawa K.

Epigenetics Chromatin. 2018 Sep 14;11(1):51. doi: 10.1186/s13072-018-0221-1.

46.

The LKB1-SIK Pathway Controls Dendrite Self-Avoidance in Purkinje Cells.

Kuwako KI, Okano H.

Cell Rep. 2018 Sep 11;24(11):2808-2818.e4. doi: 10.1016/j.celrep.2018.08.029.

47.

Responses to pup vocalizations in subordinate naked mole-rats are induced by estradiol ingested through coprophagy of queen's feces.

Watarai A, Arai N, Miyawaki S, Okano H, Miura K, Mogi K, Kikusui T.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9264-9269. doi: 10.1073/pnas.1720530115. Epub 2018 Aug 27.

48.

Calcium Transient Dynamics of Neural Ensembles in the Primary Motor Cortex of Naturally Behaving Monkeys.

Kondo T, Saito R, Otaka M, Yoshino-Saito K, Yamanaka A, Yamamori T, Watakabe A, Mizukami H, Schnitzer MJ, Tanaka KF, Ushiba J, Okano H.

Cell Rep. 2018 Aug 21;24(8):2191-2195.e4. doi: 10.1016/j.celrep.2018.07.057.

49.

Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent.

Fujimori K, Ishikawa M, Otomo A, Atsuta N, Nakamura R, Akiyama T, Hadano S, Aoki M, Saya H, Sobue G, Okano H.

Nat Med. 2018 Oct;24(10):1579-1589. doi: 10.1038/s41591-018-0140-5. Epub 2018 Aug 20.

PMID:
30127392
50.

Ambient fine and coarse particles in Japan affect nasal and bronchial epithelial cells differently and elicit varying immune response.

Onishi T, Honda A, Tanaka M, Chowdhury PH, Okano H, Okuda T, Shishido D, Terui Y, Hasegawa S, Kameda T, Tohno S, Hayashi M, Nishita-Hara C, Hara K, Inoue K, Yasuda M, Hirano S, Takano H.

Environ Pollut. 2018 Nov;242(Pt B):1693-1701. doi: 10.1016/j.envpol.2018.07.103. Epub 2018 Jul 27.

PMID:
30086990

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