Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 1194

1.

The pathogenesis linked to coenzyme Q10 insufficiency in iPSC-derived neurons from patients with multiple-system atrophy.

Nakamoto FK, Okamoto S, Mitsui J, Sone T, Ishikawa M, Yamamoto Y, Kanegae Y, Nakatake Y, Imaizumi K, Ishiura H, Tsuji S, Okano H.

Sci Rep. 2018 Sep 21;8(1):14215. doi: 10.1038/s41598-018-32573-1.

2.

Control of directionality of chromatin folding for the inter- and intra-domain contacts at the Tfap2c-Bmp7 locus.

Tsujimura T, Takase O, Yoshikawa M, Sano E, Hayashi M, Takato T, Toyoda A, Okano H, Hishikawa K.

Epigenetics Chromatin. 2018 Sep 14;11(1):51. doi: 10.1186/s13072-018-0221-1.

3.

The LKB1-SIK Pathway Controls Dendrite Self-Avoidance in Purkinje Cells.

Kuwako KI, Okano H.

Cell Rep. 2018 Sep 11;24(11):2808-2818.e4. doi: 10.1016/j.celrep.2018.08.029.

4.

Responses to pup vocalizations in subordinate naked mole-rats are induced by estradiol ingested through coprophagy of queen's feces.

Watarai A, Arai N, Miyawaki S, Okano H, Miura K, Mogi K, Kikusui T.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9264-9269. doi: 10.1073/pnas.1720530115. Epub 2018 Aug 27.

PMID:
30150390
5.

Calcium Transient Dynamics of Neural Ensembles in the Primary Motor Cortex of Naturally Behaving Monkeys.

Kondo T, Saito R, Otaka M, Yoshino-Saito K, Yamanaka A, Yamamori T, Watakabe A, Mizukami H, Schnitzer MJ, Tanaka KF, Ushiba J, Okano H.

Cell Rep. 2018 Aug 21;24(8):2191-2195.e4. doi: 10.1016/j.celrep.2018.07.057.

6.

Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent.

Fujimori K, Ishikawa M, Otomo A, Atsuta N, Nakamura R, Akiyama T, Hadano S, Aoki M, Saya H, Sobue G, Okano H.

Nat Med. 2018 Aug 20. doi: 10.1038/s41591-018-0140-5. [Epub ahead of print]

PMID:
30127392
7.

Ambient fine and coarse particles in Japan affect nasal and bronchial epithelial cells differently and elicit varying immune response.

Onishi T, Honda A, Tanaka M, Chowdhury PH, Okano H, Okuda T, Shishido D, Terui Y, Hasegawa S, Kameda T, Tohno S, Hayashi M, Nishita-Hara C, Hara K, Inoue K, Yasuda M, Hirano S, Takano H.

Environ Pollut. 2018 Nov;242(Pt B):1693-1701. doi: 10.1016/j.envpol.2018.07.103. Epub 2018 Jul 27.

PMID:
30086990
8.

Early stage clear cell adenocarcinoma of the colon examined in detail with image-enhanced endoscopy: a case report.

Tochio T, Mukai K, Baba Y, Asakawa H, Nose K, Tsuruga S, Kumazawa H, Isono Y, Tanaka H, Matsusaki S, Sase T, Saito T, Okano H, Usui M, Watanabe G.

Clin J Gastroenterol. 2018 Jul 30. doi: 10.1007/s12328-018-0889-6. [Epub ahead of print]

PMID:
30062544
9.

HER2 Heterogeneity Is Associated with Poor Survival in HER2-Positive Breast Cancer.

Hosonaga M, Arima Y, Sampetrean O, Komura D, Koya I, Sasaki T, Sato E, Okano H, Kudoh J, Ishikawa S, Saya H, Ishikawa T.

Int J Mol Sci. 2018 Jul 24;19(8). pii: E2158. doi: 10.3390/ijms19082158.

10.

Loss of DDHD2, whose mutation causes spastic paraplegia, promotes reactive oxygen species generation and apoptosis.

Maruyama T, Baba T, Maemoto Y, Hara-Miyauchi C, Hasegawa-Ogawa M, Okano HJ, Enda Y, Matsumoto K, Arimitsu N, Nakao K, Hamamoto H, Sekimizu K, Ohto-Nakanishi T, Nakanishi H, Tokuyama T, Yanagi S, Tagaya M, Tani K.

Cell Death Dis. 2018 Jul 23;9(8):797. doi: 10.1038/s41419-018-0815-3.

11.

Gastric adenocarcinoma coexisting with a reddish semipedunculated polyp arising from Helicobacter pylori-negative normal gastric mucosa: a report of two cases.

Isono Y, Baba Y, Mukai K, Asakawa H, Nose K, Tsuruga S, Tochio T, Kumazawa H, Tanaka H, Matsusaki S, Sase T, Saito T, Okano H, Toyoda H.

Clin J Gastroenterol. 2018 Jul 18. doi: 10.1007/s12328-018-0887-8. [Epub ahead of print]

PMID:
30022297
12.

Single-cell trajectory analysis of human homogenous neurons carrying a rare RELN variant.

Arioka Y, Shishido E, Kubo H, Kushima I, Yoshimi A, Kimura H, Ishizuka K, Aleksic B, Maeda T, Ishikawa M, Kuzumaki N, Okano H, Mori D, Ozaki N.

Transl Psychiatry. 2018 Jul 19;8(1):129. doi: 10.1038/s41398-018-0177-8.

13.

PAT - Probabilistic Axon Tracking for Densely Labeled Neurons in Large 3D Micrographs.

Skibbe H, Reisert M, Nakae K, Watakabe A, Hata J, Mizukami H, Okano H, Yamamori T, Ishii S.

IEEE Trans Med Imaging. 2018 Jul 13. doi: 10.1109/TMI.2018.2855736. [Epub ahead of print]

PMID:
30010551
14.

Establishment of a human induced stem cell line (FUi002-A) from Dravet syndrome patient carrying heterozygous R1525X mutation in SCN1A gene.

Tanaka Y, Higurashi N, Shirasu N, Yasunaga S, Moreira KM, Okano H, Hirose S.

Stem Cell Res. 2018 Aug;31:11-15. doi: 10.1016/j.scr.2018.06.008. Epub 2018 Jun 19.

15.

Stem cells purified from human induced pluripotent stem cell-derived neural crest-like cells promote peripheral nerve regeneration.

Kimura H, Ouchi T, Shibata S, Amemiya T, Nagoshi N, Nakagawa T, Matsumoto M, Okano H, Nakamura M, Sato K.

Sci Rep. 2018 Jul 3;8(1):10071. doi: 10.1038/s41598-018-27952-7.

16.

Japan Society of Obstetrics and Gynecology and Japan Society for Menopause and Women's Health 2017 guidelines for hormone replacement therapy.

Okano H, Higuchi T, Kurabayashi T, Makita K, Mizunuma H, Mochizuki Y, Obayashi S, Yasui T, Takamatsu K; Subcommittee for Revising the Japanese Guidelines for Hormone Replacement Therapy in the Women's Health Care Committee, Japan Society of Obstetrics and Gynecology.

J Obstet Gynaecol Res. 2018 Aug;44(8):1355-1368. doi: 10.1111/jog.13684. Epub 2018 Jun 29.

PMID:
29957860
17.

Visualization of nerve fibers around the carotid bifurcation with use of a 9.4 Tesla microscopic magnetic resonance diffusion tensor imaging with tractography.

Saito S, Ozawa H, Fujioka M, Hikishima K, Hata J, Kurihara S, Okano HJ, Ogawa K.

Head Neck. 2018 Jun 26. doi: 10.1002/hed.25318. [Epub ahead of print]

PMID:
29947092
18.

Uterine leiomyomata: a retrospective study of correlations with hypertension and diabetes mellitus from the Japan Nurses' Health Study.

Yasui T, Hayashi K, Okano H, Kamio M, Mizunuma H, Kubota T, Lee JS, Suzuki S.

J Obstet Gynaecol. 2018 Jun 8:1-7. doi: 10.1080/01443615.2018.1451987. [Epub ahead of print]

PMID:
29884084
19.

Accurate fidelity analysis of the reverse transcriptase by a modified next-generation sequencing.

Okano H, Baba M, Hidese R, Iida K, Li T, Kojima K, Takita T, Yanagihara I, Fujiwara S, Yasukawa K.

Enzyme Microb Technol. 2018 Aug;115:81-85. doi: 10.1016/j.enzmictec.2018.05.001. Epub 2018 May 3.

PMID:
29859606
20.

Optogenetic astrocyte activation evokes BOLD fMRI response with oxygen consumption without neuronal activity modulation.

Takata N, Sugiura Y, Yoshida K, Koizumi M, Hiroshi N, Honda K, Yano R, Komaki Y, Matsui K, Suematsu M, Mimura M, Okano H, Tanaka KF.

Glia. 2018 May 30. doi: 10.1002/glia.23454. [Epub ahead of print]

PMID:
29845643
21.

Are We There Yet? How and When Specific Biotechnologies Will Improve Human Health.

O'Day E, Hosta-Rigau L, OyarzĂșn DA, Okano H, de Lorenzo V, von Kameke C, Alsafar H, Cao C, Chen GQ, Ji W, Roberts RJ, Ronaghi M, Yeung K, Zhang F, Lee SY.

Biotechnol J. 2018 May 24:e1800195. doi: 10.1002/biot.201800195. [Epub ahead of print] Review.

PMID:
29799175
22.

The Amelioration of Pain-Related Behavior in Mice with Chronic Spinal Cord Injury Treated with Neural Stem/Progenitor Cell Transplantation Combined with Treadmill Training.

Tashiro S, Nishimura S, Shinozaki M, Takano M, Konomi T, Tsuji O, Nagoshi N, Toyama Y, Liu M, Okano H, Nakamura M.

J Neurotrauma. 2018 Jul 23. doi: 10.1089/neu.2017.5537. [Epub ahead of print]

PMID:
29790403
23.

Rostrocaudal Areal Patterning of Human PSC-Derived Cortical Neurons by FGF8 Signaling.

Imaizumi K, Fujimori K, Ishii S, Otomo A, Hosoi Y, Miyajima H, Warita H, Aoki M, Hadano S, Akamatsu W, Okano H.

eNeuro. 2018 Apr 26;5(2). pii: ENEURO.0368-17.2018. doi: 10.1523/ENEURO.0368-17.2018. eCollection 2018 Mar-Apr.

24.

Elavl3 regulates neuronal polarity through the alternative splicing of an embryo-specific exon in AnkyrinG.

Ogawa Y, Yamaguchi J, Yano M, Uchiyama Y, Okano HJ.

Neurosci Res. 2018 Oct;135:13-20. doi: 10.1016/j.neures.2018.03.008. Epub 2018 Mar 31.

PMID:
29614249
25.

The power of synthetic biology for bioproduction, remediation and pollution control: The UN's Sustainable Development Goals will inevitably require the application of molecular biology and biotechnology on a global scale.

de Lorenzo V, Prather KL, Chen GQ, O'Day E, von Kameke C, OyarzĂșn DA, Hosta-Rigau L, Alsafar H, Cao C, Ji W, Okano H, Roberts RJ, Ronaghi M, Yeung K, Zhang F, Lee SY.

EMBO Rep. 2018 Apr;19(4). pii: e45658. doi: 10.15252/embr.201745658. Epub 2018 Mar 26. No abstract available.

26.

A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset (Callithrix jacchus).

Kurihara S, Fujioka M, Yoshida T, Koizumi M, Ogawa K, Kojima H, Okano HJ.

J Vis Exp. 2018 Feb 27;(132). doi: 10.3791/56574.

PMID:
29553522
27.

Recurrent Spindle Cell Carcinoma Shows Features of Mesenchymal Stem Cells.

Ouchi T, Morikawa S, Shibata S, Takahashi M, Yoshikawa M, Soma T, Miyashita H, Muraoka W, Kameyama K, Kawana H, Arima Y, Saya H, Okano H, Nakagawa T, Asoda S.

J Dent Res. 2018 Jul;97(7):779-786. doi: 10.1177/0022034518759278. Epub 2018 Mar 1.

PMID:
29494307
28.

Single-cell bioluminescence imaging of deep tissue in freely moving animals.

Iwano S, Sugiyama M, Hama H, Watakabe A, Hasegawa N, Kuchimaru T, Tanaka KZ, Takahashi M, Ishida Y, Hata J, Shimozono S, Namiki K, Fukano T, Kiyama M, Okano H, Kizaka-Kondoh S, McHugh TJ, Yamamori T, Hioki H, Maki S, Miyawaki A.

Science. 2018 Feb 23;359(6378):935-939. doi: 10.1126/science.aaq1067.

PMID:
29472486
29.

Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson's disease-like motor dysfunction.

Suda Y, Kuzumaki N, Sone T, Narita M, Tanaka K, Hamada Y, Iwasawa C, Shibasaki M, Maekawa A, Matsuo M, Akamatsu W, Hattori N, Okano H, Narita M.

Mol Brain. 2018 Feb 20;11(1):6. doi: 10.1186/s13041-018-0349-8.

30.

Generation of D1-1 TALEN isogenic control cell line from Dravet syndrome patient iPSCs using TALEN-mediated editing of the SCN1A gene.

Tanaka Y, Sone T, Higurashi N, Sakuma T, Suzuki S, Ishikawa M, Yamamoto T, Mitsui J, Tsuji H, Okano H, Hirose S.

Stem Cell Res. 2018 Apr;28:100-104. doi: 10.1016/j.scr.2018.01.036. Epub 2018 Feb 2.

31.

Nestin expression is differently regulated between odontoblasts and the subodontoblastic layer in mice.

Nakatomi M, Quispe-Salcedo A, Sakaguchi M, Ida-Yonemochi H, Okano H, Ohshima H.

Histochem Cell Biol. 2018 Apr;149(4):383-391. doi: 10.1007/s00418-018-1651-3. Epub 2018 Feb 14.

PMID:
29445893
32.

Slowdown of Translational Elongation in Escherichia coli under Hyperosmotic Stress.

Dai X, Zhu M, Warren M, Balakrishnan R, Okano H, Williamson JR, Fredrick K, Hwa T.

MBio. 2018 Feb 13;9(1). pii: e02375-17. doi: 10.1128/mBio.02375-17.

33.

Chromatin remodeler CHD7 regulates the stem cell identity of human neural progenitors.

Chai M, Sanosaka T, Okuno H, Zhou Z, Koya I, Banno S, Andoh-Noda T, Tabata Y, Shimamura R, Hayashi T, Ebisawa M, Sasagawa Y, Nikaido I, Okano H, Kohyama J.

Genes Dev. 2018 Jan 15;32(2):165-180. doi: 10.1101/gad.301887.117. Epub 2018 Feb 9.

34.

The Brain/MINDS 3D digital marmoset brain atlas.

Woodward A, Hashikawa T, Maeda M, Kaneko T, Hikishima K, Iriki A, Okano H, Yamaguchi Y.

Sci Data. 2018 Feb 13;5:180009. doi: 10.1038/sdata.2018.9.

35.

Elavl3 is essential for the maintenance of Purkinje neuron axons.

Ogawa Y, Kakumoto K, Yoshida T, Kuwako KI, Miyazaki T, Yamaguchi J, Konno A, Hata J, Uchiyama Y, Hirai H, Watanabe M, Darnell RB, Okano H, Okano HJ.

Sci Rep. 2018 Feb 9;8(1):2722. doi: 10.1038/s41598-018-21130-5.

36.

Ultrasound-guided identification of the cricothyroid membrane in a patient with a difficult airway: a case report.

Okano H, Uzawa K, Watanabe K, Motoyasu A, Tokumine J, Lefor AK, Yorozu T.

BMC Emerg Med. 2018 Feb 8;18(1):5. doi: 10.1186/s12873-018-0156-7.

37.

Nitrative Stress and Tau Accumulation in Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) in the Kii Peninsula, Japan.

Hata Y, Ma N, Yoneda M, Morimoto S, Okano H, Murayama S, Kawanishi S, Kuzuhara S, Kokubo Y.

Front Neurosci. 2018 Jan 22;11:751. doi: 10.3389/fnins.2017.00751. eCollection 2017.

38.

Japan Strengthens Regenerative Medicine Oversight.

Sipp D, Okano H.

Cell Stem Cell. 2018 Feb 1;22(2):153-156. doi: 10.1016/j.stem.2018.01.001.

PMID:
29395052
39.

Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice.

Takeda H, Hosoya M, Fujioka M, Saegusa C, Saeki T, Miwa T, Okano H, Minoda R.

Sci Rep. 2018 Jan 31;8(1):1941. doi: 10.1038/s41598-018-20277-5.

40.

Activation of ventral tegmental area dopaminergic neurons reverses pathological allodynia resulting from nerve injury or bone cancer.

Watanabe M, Narita M, Hamada Y, Yamashita A, Tamura H, Ikegami D, Kondo T, Shinzato T, Shimizu T, Fukuchi Y, Muto A, Okano H, Yamanaka A, Tawfik VL, Kuzumaki N, Navratilova E, Porreca F, Narita M.

Mol Pain. 2018 Jan-Dec;14:1744806918756406. doi: 10.1177/1744806918756406. Epub 2018 Jan 22.

41.

Chemical decontamination of iPS cell-derived neural cell mixtures.

Mao D, Chung XKW, Andoh-Noda T, Qin Y, Sato SI, Takemoto Y, Akamatsu W, Okano H, Uesugi M.

Chem Commun (Camb). 2018 Feb 1;54(11):1355-1358. doi: 10.1039/c7cc08686e.

PMID:
29350722
42.

Aqueous and organic extract of PM2.5 collected in different seasons and cities of Japan differently affect respiratory and immune systems.

Chowdhury PH, Okano H, Honda A, Kudou H, Kitamura G, Ito S, Ueda K, Takano H.

Environ Pollut. 2018 Apr;235:223-234. doi: 10.1016/j.envpol.2017.12.040. Epub 2018 Jan 4.

PMID:
29291522
43.

Generation of Induced Pluripotent Stem Cells and Neural Stem/Progenitor Cells from Newborns with Spina Bifida Aperta.

Bamba Y, Nonaka M, Sasaki N, Shofuda T, Kanematsu D, Suemizu H, Higuchi Y, Pooh RK, Kanemura Y, Okano H, Yamasaki M.

Asian Spine J. 2017 Dec;11(6):870-879. doi: 10.4184/asj.2017.11.6.870. Epub 2017 Dec 7.

44.

Isolation of dental pulp stem cells with high osteogenic potential.

Yasui T, Mabuchi Y, Morikawa S, Onizawa K, Akazawa C, Nakagawa T, Okano H, Matsuzaki Y.

Inflamm Regen. 2017 Apr 10;37:8. doi: 10.1186/s41232-017-0039-4. eCollection 2017. Review.

45.

CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations.

Okuno H, Renault Mihara F, Ohta S, Fukuda K, Kurosawa K, Akamatsu W, Sanosaka T, Kohyama J, Hayashi K, Nakajima K, Takahashi T, Wysocka J, Kosaki K, Okano H.

Elife. 2017 Nov 28;6. pii: e21114. doi: 10.7554/eLife.21114.

46.

Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system.

Yamanaka S, Tajiri S, Fujimoto T, Matsumoto K, Fukunaga S, Kim BS, Okano HJ, Yokoo T.

Nat Commun. 2017 Nov 23;8(1):1719. doi: 10.1038/s41467-017-01922-5.

47.

The Semaphorin 3A inhibitor SM-345431 preserves corneal nerve and epithelial integrity in a murine dry eye model.

Yamazaki R, Yamazoe K, Yoshida S, Hatou S, Inagaki E, Okano H, Tsubota K, Shimmura S.

Sci Rep. 2017 Nov 14;7(1):15584. doi: 10.1038/s41598-017-15682-1.

48.

Author Correction: Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway.

Morizawa YM, Hirayama Y, Ohno N, Shibata S, Shigetomi E, Sui Y, Nabekura J, Sato K, Okajima F, Takebayashi H, Okano H, Koizumi S.

Nat Commun. 2017 Nov 14;8(1):1598. doi: 10.1038/s41467-017-01594-1.

49.

Naive-like ESRRB+ iPSCs with the Capacity for Rapid Neural Differentiation.

Kisa F, Shiozawa S, Oda K, Yoshimatsu S, Nakamura M, Koya I, Kawai K, Suzuki S, Okano H.

Stem Cell Reports. 2017 Dec 12;9(6):1825-1838. doi: 10.1016/j.stemcr.2017.10.008. Epub 2017 Nov 9.

50.

Investigation of brain science and neurological/psychiatric disorders using genetically modified non-human primates.

Okano H, Kishi N.

Curr Opin Neurobiol. 2018 Jun;50:1-6. doi: 10.1016/j.conb.2017.10.016. Epub 2017 Nov 7. Review.

PMID:
29125958

Supplemental Content

Support Center