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Items: 1 to 50 of 931

1.

Discovery of 1,8-naphthyridin-2-one derivative as a potent and selective sphingomyelin synthase 2 inhibitor.

Yukawa T, Nakahata T, Okamoto R, Ishichi Y, Miyamoto Y, Nishimura S, Oikawa T, Kubo K, Adachi R, Satomi Y, Nakakariya M, Amano N, Kamaura M, Matsunaga N.

Bioorg Med Chem. 2020 Feb 12:115376. doi: 10.1016/j.bmc.2020.115376. [Epub ahead of print]

PMID:
32088125
2.

Effect of cosyntropin during adrenal venous sampling on subtype of primary aldosteronism: analysis of surgical outcome.

Kobayashi H, Nakamura Y, Abe M, Kurihara I, Itoh H, Ichijo T, Takeda Y, Yoneda T, Katabami T, Tsuiki M, Wada N, Ogawa Y, Sakamoto R, Kawashima J, Sone M, Inagaki N, Yoshimoto T, Yamada T, Okamoto R, Matsuda Y, Fujita M, Watanabe M, Tamura K, Tanabe A, Naruse M; JPAS/JRAS Study Group.

Eur J Endocrinol. 2020 Mar;182(3):265-273. doi: 10.1530/EJE-19-0860.

PMID:
32038030
3.

TGF-β promotes fetal gene expression and cell migration velocity in a wound repair model of untransformed intestinal epithelial cells.

Anzai S, Kawamoto A, Nagata S, Takahashi J, Kawai M, Kuno R, Kobayashi S, Watanabe S, Suzuki K, Shimizu H, Hiraguri Y, Takeoka S, Sugihara HY, Yui S, Oshima S, Watanabe M, Okamoto R.

Biochem Biophys Res Commun. 2020 Jan 31. pii: S0006-291X(20)30183-2. doi: 10.1016/j.bbrc.2020.01.108. [Epub ahead of print]

PMID:
32014254
4.

Multi-Excitation MR Elastography of the Brain: Wave Propagation in Anisotropic White Matter.

Smith D, Guertler CA, Okamoto RJ, Romano A, Bayly PV, Johnson CL.

J Biomech Eng. 2020 Feb 3. doi: 10.1115/1.4046199. [Epub ahead of print]

PMID:
32006012
5.

Receptor-Interacting Protein Kinase 3 (RIPK3) inhibits autophagic flux during necroptosis in intestinal epithelial cells.

Otsubo K, Maeyashiki C, Nibe Y, Tamura A, Aonuma E, Matsuda H, Kobayashi M, Onizawa M, Nemoto Y, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Torii S, Itakura E, Watanabe M, Oshima S.

FEBS Lett. 2020 Jan 29. doi: 10.1002/1873-3468.13748. [Epub ahead of print]

PMID:
31997355
6.

Estimation of Anisotropic Material Properties of Soft Tissue by Mri of Ultrasound-induced Shear Waves.

Guertler CA, Okamoto RJ, Ireland J, Pacia C, Garbow JR, Chen H, Bayly PV.

J Biomech Eng. 2020 Jan 1. doi: 10.1115/1.4046127. [Epub ahead of print]

PMID:
31980814
7.

Organoid-based regenerative medicine for inflammatory bowel disease.

Okamoto R, Shimizu H, Suzuki K, Kawamoto A, Takahashi J, Kawai M, Nagata S, Hiraguri Y, Takeoka S, Sugihara HY, Yui S, Watanabe M.

Regen Ther. 2020 Jan 13;13:1-6. doi: 10.1016/j.reth.2019.11.004. eCollection 2020 Mar. Review.

8.

Understanding the formation and behaviors of droplets toward consideration of changeover during cell manufacturing.

Ogawa Y, Mizutani M, Okamoto R, Kitajima H, Ezoe S, Kino-Oka M.

Regen Ther. 2019 Apr 25;12:36-42. doi: 10.1016/j.reth.2019.04.002. eCollection 2019 Dec 15.

9.

Color single-pixel digital holography with a phase-encoded reference wave.

Endo Y, Tahara T, Okamoto R.

Appl Opt. 2019 Dec 1;58(34):G149-G154. doi: 10.1364/AO.58.00G149.

PMID:
31873497
10.

CD8αα+ T cells show amoeboid shape and frequent morphological change in vitro, and localize to small intestinal intraepithelial region in vivo.

Takei Y, Nemoto Y, Morikawa R, Tanaka S, Oshima S, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Watanabe M.

Biochem Biophys Res Commun. 2020 Mar 5;523(2):328-335. doi: 10.1016/j.bbrc.2019.12.021. Epub 2019 Dec 19.

PMID:
31864702
11.

Total Chemical Synthesis of a Nonfibrillating Human Glycoinsulin.

Hossain MA, Okamoto R, Karas JA, Praveen P, Liu M, Forbes BE, Wade JD, Kajihara Y.

J Am Chem Soc. 2020 Jan 22;142(3):1164-1169. doi: 10.1021/jacs.9b11424. Epub 2020 Jan 9.

PMID:
31850747
12.

High-fat diet-derived free fatty acids impair the intestinal immune system and increase sensitivity to intestinal epithelial damage.

Tanaka S, Nemoto Y, Takei Y, Morikawa R, Oshima S, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Stutte S, Watanabe M.

Biochem Biophys Res Commun. 2020 Feb 19;522(4):971-977. doi: 10.1016/j.bbrc.2019.11.158. Epub 2019 Dec 3.

PMID:
31810607
13.

[Effects of facial rehabilitation exercise on the mood, facial expressions, and facial muscle activities in patients with Parkinson's disease].

Okamoto R, Adachi K, Mizukami K.

Nihon Ronen Igakkai Zasshi. 2019;56(4):478-486. doi: 10.3143/geriatrics.56.478. Japanese.

14.

Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]Pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 2.

Kaieda A, Takahashi M, Fukuda H, Okamoto R, Morimoto S, Gotoh M, Miyazaki T, Hori Y, Unno S, Kawamoto T, Tanaka T, Itono S, Takagi T, Sugimoto H, Okada K, Lane W, Sang BC, Saikatendu K, Matsunaga S, Miwatashi S.

ChemMedChem. 2019 Dec 17;14(24):2093-2101. doi: 10.1002/cmdc.201900373. Epub 2019 Nov 7.

PMID:
31697454
15.

Bone tissue formation around two titanium implant surfaces placed in bone defects filled with bone substitute material or blood clot: A pilot study.

Trento GDS, Spin-Neto R, Bassi APF, Okamoto R, Gabrielli MAC, Pereira-Filho VA.

Clin Implant Dent Relat Res. 2019 Dec;21(6):1175-1180. doi: 10.1111/cid.12855. Epub 2019 Nov 6.

PMID:
31691471
16.

Competency model for public health nurses working on tobacco control in local governments in Japan: A qualitative study.

Michibayashi C, Omote S, Nakamura M, Okamoto R, Nakada AI.

Jpn J Nurs Sci. 2020 Jan;17(1):e12288. doi: 10.1111/jjns.12288. Epub 2019 Oct 23.

PMID:
31642605
18.

Losartan improves alveolar bone dynamics in normotensive rats but not in hypertensive rats.

Mulinari-Santos G, Santos JSD, Palin LP, Silva ACED, Antoniali C, Faverani LP, Okamoto R.

J Appl Oral Sci. 2019 Oct 7;27:e20180574. doi: 10.1590/1678-7757-2018-0574. eCollection 2019.

19.

Magnetic Resonance Imaging Findings of All-Trans Retinoic Acid-induced Pseudotumor Cerebri in a Child With Acute Promyelocytic Leukemia.

Shirai R, Tomizawa D, Okamoto R, Matsumoto K, Miyazaki O.

J Pediatr Hematol Oncol. 2020 Mar;42(2):138-140. doi: 10.1097/MPH.0000000000001610.

PMID:
31593006
20.

Association of dioxin in maternal breast milk and salivary steroid hormone levels in preschool children: A five-year follow-up study of a Vietnam cohort.

Sun XL, Okamoto R, Kido T, Honma S, Manh HD, Nguyen HV, Anh LT, Phuc HD, Oanh NTP, Maruzeni S, Nakagawa H, Nakayama SF, Nhu DD, Tung DV, Tan NTM, Giang LM.

Chemosphere. 2020 Feb;241:124899. doi: 10.1016/j.chemosphere.2019.124899. Epub 2019 Sep 22.

PMID:
31586830
21.

The status and future directions of comprehensive tobacco control policies for the 2020 Tokyo Olympic Games: A review.

Li M, Tada A, Kiya M, Okamoto R.

Tob Induc Dis. 2019 Apr 1;17:24. doi: 10.18332/tid/105453. eCollection 2019. Review.

22.

Selective Phenylimidazole-Based Inhibitors of the Mycobacterium tuberculosis Proteasome.

Zhan W, Hsu HC, Morgan T, Ouellette T, Burns-Huang K, Hara R, Wright AG, Imaeda T, Okamoto R, Sato K, Michino M, Ramjee M, Aso K, Meinke PT, Foley M, Nathan CF, Li H, Lin G.

J Med Chem. 2019 Oct 24;62(20):9246-9253. doi: 10.1021/acs.jmedchem.9b01187. Epub 2019 Oct 15.

PMID:
31560200
23.

Inflammatory marker and aryl hydrocarbon receptor-dependent responses in human macrophages exposed to emissions from biodiesel fuels.

Vogel CFA, Kado SY, Kobayashi R, Liu X, Wong P, Na K, Durbin T, Okamoto RA, Kado NY.

Chemosphere. 2019 Apr;220:993-1002. doi: 10.1016/j.chemosphere.2018.12.178. Epub 2018 Dec 26.

24.

[Workplace preparedness and recognition of the continued employment of employees with early onset dementia].

Omote S, Ishiwata T, Okamoto R, Nakata Ichimori A, Morikawa Y, Koyama Y, Ikeuchi S, Okuno T, Takahashi Y, Kido T.

Sangyo Eiseigaku Zasshi. 2019 Sep 13. doi: 10.1539/sangyoeisei.2018-043-E. [Epub ahead of print] Japanese.

25.

Shear Wave Propagation and Estimation of Material Parameters in a Nonlinear, Fibrous Material.

Hou Z, Okamoto RJ, Bayly PV.

J Biomech Eng. 2019 Aug 1. doi: 10.1115/1.4044504. [Epub ahead of print]

PMID:
31513702
26.

Overlooked pericarditis complicated with cardiac tamponade due to an uncommon cause.

Fukuma T, Okamoto R, Nakata T, Hoshino K, Ito M.

Eur Heart J Cardiovasc Imaging. 2020 Jan 1;21(1):116. doi: 10.1093/ehjci/jez183. No abstract available.

PMID:
31504354
27.

Development of Organelle Replacement Therapy Using a Stearyl-Polyhistidine Peptide against Lysosomal Storage Disease Cells.

Hayashi T, Okamoto R, Kawano T, Iwasaki T.

Molecules. 2019 Aug 18;24(16). pii: E2995. doi: 10.3390/molecules24162995.

28.

Stem cell-based therapy for inflammatory bowel disease.

Shimizu H, Suzuki K, Watanabe M, Okamoto R.

Intest Res. 2019 Jul;17(3):311-316. doi: 10.5217/ir.2019.00043. Epub 2019 Jul 25. Review.

29.

Improvement of bone repair with l-PRF and bovine bone in calvaria of rats. histometric and immunohistochemical study.

do Lago ES, Ferreira S, Garcia IR Jr, Okamoto R, Mariano RC.

Clin Oral Investig. 2019 Jul 23. doi: 10.1007/s00784-019-03018-4. [Epub ahead of print]

PMID:
31338633
30.

BNP as a Major Player in the Heart-Kidney Connection.

Okamoto R, Ali Y, Hashizume R, Suzuki N, Ito M.

Int J Mol Sci. 2019 Jul 22;20(14). pii: E3581. doi: 10.3390/ijms20143581. Review.

31.

Safety and efficacy of amnion-derived mesenchymal stem cells (AM01) in patients with steroid-refractory acute graft-versus-host disease after allogeneic haematopoietic stem cell transplantation: a study protocol for a phase I/II Japanese trial.

Yamahara K, Hamada A, Soma T, Okamoto R, Okada M, Yoshihara S, Yoshihara K, Ikegame K, Tamaki H, Kaida K, Inoue T, Ohsugi Y, Nishikawa H, Hayashi H, Ito YM, Iijima H, Ohnishi S, Hashimoto D, Isoe T, Teshima T, Ogawa H, Sato N, Fujimori Y.

BMJ Open. 2019 Jul 9;9(7):e026403. doi: 10.1136/bmjopen-2018-026403.

32.

Multi-season analyses of causative pathogens in children hospitalized with asthma exacerbation.

Abe N, Yasudo H, Fukano R, Nakamura T, Okada S, Wakiguchi H, Okazaki F, Shirabe K, Toda S, Okamoto R, Ouchi K, Ohga S, Hasegawa S.

Pediatr Allergy Immunol. 2019 Nov;30(7):724-731. doi: 10.1111/pai.13102. Epub 2019 Aug 12.

PMID:
31251831
33.

Strategy of Mandibular Central Arch Reconstruction After Firearm Injury.

Fernandes BDR, Mendes BC, Mulinari-Santos G, Okamoto R, Homsi N, Rocha-Jr HVD, Magacho LF, Pereira RDS.

J Craniofac Surg. 2019 Oct;30(7):e629-e630. doi: 10.1097/SCS.0000000000005655.

PMID:
31157639
34.

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.

Lama L, Adura C, Xie W, Tomita D, Kamei T, Kuryavyi V, Gogakos T, Steinberg JI, Miller M, Ramos-Espiritu L, Asano Y, Hashizume S, Aida J, Imaeda T, Okamoto R, Jennings AJ, Michino M, Kuroita T, Stamford A, Gao P, Meinke P, Glickman JF, Patel DJ, Tuschl T.

Nat Commun. 2019 May 21;10(1):2261. doi: 10.1038/s41467-019-08620-4.

35.

Chemical Modification of the N Termini of Unprotected Peptides for Semisynthesis of Modified Proteins by Utilizing a Hydrophilic Protecting Group.

Chandrashekar C, Okamoto R, Izumi M, Kajihara Y.

Chemistry. 2019 Aug 1;25(43):10197-10203. doi: 10.1002/chem.201901778. Epub 2019 Jul 1.

PMID:
31106456
36.

Sonochemical time standardization for bioactive materials used in periimplantar defects filling.

Gomes-Ferreira PHS, Lisboa-Filho PN, da Silva AC, Bim-Júnior O, de Souza Batista FR, Ervolino-Silva AC, Garcia-Junior IR, Okamoto R.

Ultrason Sonochem. 2019 Sep;56:437-446. doi: 10.1016/j.ultsonch.2019.04.032. Epub 2019 Apr 22.

PMID:
31101282
37.

Teriparatide improves alveolar bone modelling after tooth extraction in orchiectomized rats.

de Oliveira Puttini I, Gomes-Ferreira PHDS, de Oliveira D, Hassumi JS, Gonçalves PZ, Okamoto R.

Arch Oral Biol. 2019 Jun;102:147-154. doi: 10.1016/j.archoralbio.2019.04.007. Epub 2019 Apr 16.

PMID:
31022626
38.

Insights Into Traumatic Brain Injury From MRI of Harmonic Brain Motion.

Okamoto RJ, Romano AJ, Johnson CL, Bayly PV.

J Exp Neurosci. 2019 Apr 7;13:1179069519840444. doi: 10.1177/1179069519840444. eCollection 2019.

39.

TP53 Mutation by CRISPR System Enhances the Malignant Potential of Colon Cancer.

Watanabe S, Tsuchiya K, Nishimura R, Shirasaki T, Katsukura N, Hibiya S, Okamoto R, Nakamura T, Watanabe M.

Mol Cancer Res. 2019 Jul;17(7):1459-1467. doi: 10.1158/1541-7786.MCR-18-1195. Epub 2019 Apr 15.

PMID:
30988165
40.

N,N-Dimethylaminoxy Carbonyl, a Polar Protecting Group for Efficient Peptide Synthesis.

Okamoto R, Ono E, Izumi M, Kajihara Y.

Front Chem. 2019 Mar 28;7:173. doi: 10.3389/fchem.2019.00173. eCollection 2019.

41.

Angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers in hypertensive patients with myocardial infarction or heart failure: a systematic review and meta-analysis.

Ohtsubo T, Shibata R, Kai H, Okamoto R, Kumagai E, Kawano H, Fujiwara A, Kitazono T, Murohara T, Arima H.

Hypertens Res. 2019 May;42(5):641-649. doi: 10.1038/s41440-018-0167-5. Epub 2019 Apr 5.

PMID:
30948834
42.

Effects of lowering diastolic blood pressure to <80 mmHg on cardiovascular mortality and events in patients with coronary artery disease: a systematic review and meta-analysis.

Okamoto R, Kumagai E, Kai H, Shibata R, Ohtsubo T, Kawano H, Fujiwara A, Ito M, Fukumoto Y, Arima H.

Hypertens Res. 2019 May;42(5):650-659. doi: 10.1038/s41440-018-0189-z. Epub 2019 Apr 5.

PMID:
30948833
43.

Effects of blood pressure lowering in patients with heart failure with preserved ejection fraction: a systematic review and meta-analysis.

Kawano H, Fujiwara A, Kai H, Kumagai E, Okamoto R, Shibata R, Ohtsubo T, Tamura K, Maemura K, Arima H.

Hypertens Res. 2019 Apr;42(4):504-513. doi: 10.1038/s41440-019-0216-8. Epub 2019 Apr 5.

PMID:
30948821
44.

Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 1.

Kaieda A, Takahashi M, Fukuda H, Okamoto R, Morimoto S, Gotoh M, Miyazaki T, Hori Y, Unno S, Kawamoto T, Tanaka T, Itono S, Takagi T, Sugimoto H, Okada K, Snell G, Bertsch R, Nguyen J, Sang BC, Miwatashi S.

ChemMedChem. 2019 May 17;14(10):1022-1030. doi: 10.1002/cmdc.201900129. Epub 2019 Apr 18.

PMID:
30945818
45.

Use of Calcium Phosphate Cement for Repairing Bone Defects: Histomorphometric and Immunohistochemical Analyses.

Gulinelli JL, Queiroz TP, Hochuli-Vieira E, Okamoto R, Mattos JMB, Calcagnotto T, Santos PLD.

J Craniofac Surg. 2019 Jun;30(4):1016-1021. doi: 10.1097/SCS.0000000000005526.

PMID:
30908445
46.

Prevalence and mechanism of fluoroquinolone resistance in clinical isolates of Proteus mirabilis in Japan.

Nakano R, Nakano A, Abe M, Nagano N, Asahara M, Furukawa T, Ono Y, Yano H, Okamoto R.

Heliyon. 2019 Mar 2;5(3):e01291. doi: 10.1016/j.heliyon.2019.e01291. eCollection 2019 Mar.

47.

Glucocorticoids promote breast cancer metastasis.

Obradović MMS, Hamelin B, Manevski N, Couto JP, Sethi A, Coissieux MM, Münst S, Okamoto R, Kohler H, Schmidt A, Bentires-Alj M.

Nature. 2019 Mar;567(7749):540-544. doi: 10.1038/s41586-019-1019-4. Epub 2019 Mar 13.

PMID:
30867597
48.

Physical Properties and In Vitro Biocompatible Evaluation of Silicone-Modified Polyurethane Nanofibers and Films.

Yin C, Rozet S, Okamoto R, Kondo M, Tamada Y, Tanaka T, Hattori H, Tanaka M, Sato H, Iino S.

Nanomaterials (Basel). 2019 Mar 5;9(3). pii: E367. doi: 10.3390/nano9030367.

49.

Novel molecular mechanisms in the inhibition of adrenal aldosterone synthesis: Action of tolvaptan via vasopressin V2 receptor-independent pathway.

Ali Y, Dohi K, Okamoto R, Katayama K, Ito M.

Br J Pharmacol. 2019 May;176(9):1315-1327. doi: 10.1111/bph.14630. Epub 2019 Apr 7.

PMID:
30801659
50.

Regioselective α-Peptide Bond Formation Through the Oxidation of Amino Thioacids.

Okamoto R, Haraguchi T, Nomura K, Maki Y, Izumi M, Kajihara Y.

Biochemistry. 2019 Mar 26;58(12):1672-1678. doi: 10.1021/acs.biochem.8b01239. Epub 2019 Mar 8.

PMID:
30789713

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