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Preoperative sepsis is a predictive factor for 30-day mortality after major lower limb amputation among patients with arteriosclerosis obliterans and diabetes.

Otsuka T, Arai M, Sugimura K, Sakai M, Nishizawa Y, Suzuki Y, Okamoto H, Kuroiwa M.

J Orthop Sci. 2019 Jun 18. pii: S0949-2658(19)30152-6. doi: 10.1016/j.jos.2019.05.017. [Epub ahead of print]


A Nationwide Survey of Hepatitis E Virus Infection and Chronic Hepatitis in Heart and Kidney Transplant Recipients in Japan.

Owada Y, Oshiro Y, Inagaki Y, Harada H, Fujiyama N, Kawagishi N, Yagisawa T, Usui J, Akutsu N, Itabashi Y, Saito K, Watarai Y, Ichimaru N, Imamura R, Kyakuno M, Ide K, Shibuya Y, Okabe Y, Ono M, Sasaki K, Shiose A, Yamagishi K, Ohnishi H, Nagashima S, Takahashi M, Yuzawa K, Okamoto H, Ohkohchi N.

Transplantation. 2019 May 20. doi: 10.1097/TP.0000000000002801. [Epub ahead of print]


Doublon-holon pairing mechanism via exchange interaction in two-dimensional cuprate Mott insulators.

Terashige T, Ono T, Miyamoto T, Morimoto T, Yamakawa H, Kida N, Ito T, Sasagawa T, Tohyama T, Okamoto H.

Sci Adv. 2019 Jun 7;5(6):eaav2187. doi: 10.1126/sciadv.aav2187. eCollection 2019 Jun.


Wide and Deep Imaging of Neuronal Activities by a Wearable NeuroImager Reveals Premotor Activity in the Whole Motor Cortex.

Kobayashi T, Islam T, Sato M, Ohkura M, Nakai J, Hayashi Y, Okamoto H.

Sci Rep. 2019 Jun 10;9(1):8366. doi: 10.1038/s41598-019-44146-x.


Reconstructed gastric conduit obstruction caused by a bezoar after esophagectomy: a case report.

Hatoyama K, Taniyama Y, Sakurai T, Hikage M, Sato C, Okamoto H, Takaya K, Onodera Y, Kamei T.

BMC Surg. 2019 Jun 7;19(1):59. doi: 10.1186/s12893-019-0525-5.


T-wave changes of cardiac memory caused by frequent premature ventricular contractions originating from the right ventricular outflow tract.

Sakamoto Y, Inden Y, Okamoto H, Mamiya K, Tomomatsu T, Fujii A, Yanagisawa S, Shibata R, Hirai M, Murohara T.

J Cardiovasc Electrophysiol. 2019 Jun 3. doi: 10.1111/jce.14008. [Epub ahead of print]


Clinical characteristics of sarcoidosis patients with systemic sclerosis-specific autoantibody: Possible involvement of thymus and activation-regulated chemokine and a review of the published works.

Ueda-Hayakawa I, Nguyen CTH, Kishimoto I, Ly NTM, Okamoto H.

J Dermatol. 2019 May 27. doi: 10.1111/1346-8138.14932. [Epub ahead of print]


Sofosbuvir/Ribavirin therapy for patients experiencing failure of ombitasvir/paritaprevir/ritonavir + ribavirin therapy: Two cases report and review of literature.

Sato K, Yamazaki Y, Kobayashi T, Takakusagi S, Horiguchi N, Kakizaki S, Andou M, Matsuda Y, Uraoka T, Ohnishi H, Okamoto H.

World J Clin Cases. 2019 May 6;7(9):1043-1052. doi: 10.12998/wjcc.v7.i9.1043.


Efficacy and Safety of the Ultra-Short-Acting β1-Selective Blocker Landiolol in Patients With Recurrent Hemodynamically Unstable Ventricular Tachyarrhymias - Outcomes of J-Land II Study.

Ikeda T, Shiga T, Shimizu W, Kinugawa K, Sakamoto A, Nagai R, Daimon T, Oki K, Okamoto H, Yamashita T; J-Land II Study Investigators.

Circ J. 2019 May 23. doi: 10.1253/circj.CJ-18-1361. [Epub ahead of print]


Genetic Variability and Evolution of Hepatitis E Virus.

Primadharsini PP, Nagashima S, Okamoto H.

Viruses. 2019 May 18;11(5). pii: E456. doi: 10.3390/v11050456. Review.


Daily growth increments in otoliths of wild-caught honmoroko Gnathopogon caerulescens.

Kikko T, Ishizaki D, Yodo T, Aino S, Kuwamura K, Okamoto H, Nemoto M, Yoneda K, Oue N, Sakai A, Fujioka Y, Kai Y, Sato T, Nakayama K.

J Fish Biol. 2019 May 14. doi: 10.1111/jfb.14008. [Epub ahead of print]


Phase II trial of S-1 plus cisplatin combined with bevacizumab for advanced non-squamous non-small cell lung cancer (TCOG LC-1202).

Miyanaga A, Kubota K, Hosomi Y, Okuma Y, Minato K, Fujimoto S, Okamoto H, Satouchi M, Isobe H, Aono H, Takiguchi Y, Gemma A; Tokyo Cooperative Oncology Group.

Jpn J Clin Oncol. 2019 May 9. pii: hyz064. doi: 10.1093/jjco/hyz064. [Epub ahead of print]


MX-type single chain complexes with an aromatic in-plane ligand: incorporation of aromatic interactions for stabilizing the chain structure.

Afrin U, Iguchi H, Mian MR, Takaishi S, Yamakawa H, Terashige T, Miyamoto T, Okamoto H, Yamashita M.

Dalton Trans. 2019 Jun 14;48(22):7828-7834. doi: 10.1039/c9dt00784a. Epub 2019 May 9.


Acute esophageal necrosis with esophagus perforation treated by thoracoscopic subtotal esophagectomy and reconstructive surgery on a secondary esophageal stricture: a case report.

Akaishi R, Taniyama Y, Sakurai T, Okamoto H, Sato C, Unno M, Kamei T.

Surg Case Rep. 2019 May 8;5(1):73. doi: 10.1186/s40792-019-0636-3.


Dose escalation of external beam radiotherapy for high-risk prostate cancer-Impact of multiple high-risk factor.

Umezawa R, Inaba K, Nakamura S, Wakita A, Okamoto H, Tsuchida K, Kashihara T, Kobayashi K, Harada K, Takahashi K, Murakami N, Ito Y, Igaki H, Jingu K, Itami J.

Asian J Urol. 2019 Apr;6(2):192-199. doi: 10.1016/j.ajur.2017.07.002. Epub 2017 Oct 19.


Resveratrol‑induced REG III expression enhances chemo‑ and radiosensitivity in head and neck cancer in xenograft mice.

Mikami S, Ota I, Masui T, Uchiyama T, Okamoto H, Kimura T, Takasawa S, Kitahara T.

Oncol Rep. 2019 Jul;42(1):436-442. doi: 10.3892/or.2019.7137. Epub 2019 Apr 25.


Changing clinical and molecular characteristics of hepatitis E virus infection in Mie Prefecture, Japan: Disappearance of indigenous subtype 3e strains.

Nakano T, Okano H, Takahashi M, Nagashima S, Shiraki K, Oya Y, Inoue H, Ohmori S, Tsukimoto M, Ishida S, Fujimoto S, Kobayashi M, Yamawaki M, Kumagai M, Ninomiya J, Maegawa T, Kojima Y, Araki J, Hamaoka S, Horiike S, Yoshimura H, Takeuchi K, Itoh K, Akachi S, Uraki S, Yamamoto N, Ogura S, Sugimoto K, Yoshikawa K, Hasegawa H, Iwasa M, Takei Y, Okamoto H.

Hepatol Res. 2019 Apr 26. doi: 10.1111/hepr.13357. [Epub ahead of print]


Evaluation of the extent of damage to the esophageal wall caused by press-through package ingestion.

Tamura T, Okamoto H, Suzuki T, Nakanishi Y, Sugiyama D.

PeerJ. 2019 Apr 18;7:e6763. doi: 10.7717/peerj.6763. eCollection 2019.


Primary Percutaneous Coronary Intervention in Elderly Patients With Acute Myocardial Infarction - An Analysis From a Japanese Nationwide Claim-Based Database.

Uemura S, Okamoto H, Nakai M, Nishimura K, Miyamoto Y, Yasuda S, Tanaka N, Kohsaka S, Kadota K, Saito Y, Tsutsui H, Komuro I, Ikari Y, Ogawa H, Nakamura M.

Circ J. 2019 May 24;83(6):1229-1238. doi: 10.1253/circj.CJ-19-0004. Epub 2019 Apr 24.


Screening of novel drugs for inhibiting hepatitis E virus replication.

Nishiyama T, Kobayashi T, Jirintai S, Kii I, Nagashima S, Prathiwi Primadharsini P, Nishizawa T, Okamoto H.

J Virol Methods. 2019 Aug;270:1-11. doi: 10.1016/j.jviromet.2019.04.017. Epub 2019 Apr 17.


Transcriptomic analysis reveals differences in the regulation of amino acid metabolism in asexual and sexual planarians.

Sekii K, Yorimoto S, Okamoto H, Nagao N, Maezawa T, Matsui Y, Yamaguchi K, Furukawa R, Shigenobu S, Kobayashi K.

Sci Rep. 2019 Apr 16;9(1):6132. doi: 10.1038/s41598-019-42025-z.


RNA-sequencing reveals altered skeletal muscle contraction, E3 ligases, autophagy, apoptosis, and chaperone expression in patients with critical illness myopathy.

Llano-Diez M, Fury W, Okamoto H, Bai Y, Gromada J, Larsson L.

Skelet Muscle. 2019 Apr 16;9(1):9. doi: 10.1186/s13395-019-0194-1.


[Cutaneous Lesions of Sarcoidosis].

Okamoto H.

Brain Nerve. 2019 Apr;71(4):345-349. doi: 10.11477/mf.1416201273. Japanese.


Treatment of a Malignant Soft Tissue Tumor Arising in the Vicinity of the Sciatic Nerve with an In-Situ Preparation Technique and Intensive Multidisciplinary Therapy.

Aiba H, Hayashi K, Yamada S, Okamoto H, Kimura H, Miwa S, Inatani H, Otsuka T, Murakami H.

Cancers (Basel). 2019 Apr 10;11(4). pii: E506. doi: 10.3390/cancers11040506.


Low-dose of olanzapine has ameliorating effects on cancer-related anorexia.

Okamoto H, Shono K, Nozaki-Taguchi N.

Cancer Manag Res. 2019 Mar 19;11:2233-2239. doi: 10.2147/CMAR.S191330. eCollection 2019.


Association of bioimpedance phase angle and prospective falls in older adults.

Uemura K, Yamada M, Okamoto H.

Geriatr Gerontol Int. 2019 Jun;19(6):503-507. doi: 10.1111/ggi.13651. Epub 2019 Apr 8.


Establishment of an Evaluation Method for Gene Silencing by Serial Pulmonary Administration of siRNA and pDNA Powders: Naked siRNA Inhalation Powder Suppresses Luciferase Gene Expression in the Lung.

Ito T, Okuda T, Takayama R, Okamoto H.

J Pharm Sci. 2019 Apr 5. pii: S0022-3549(19)30212-6. doi: 10.1016/j.xphs.2019.03.029. [Epub ahead of print]


Synthesis of Chiral Labtb and Visualization of Its Enantiomeric Excess by Induced Circular Dichroism Imaging.

Yamada T, Eguchi T, Wakiyama T, Narushima T, Okamoto H, Kimizuka N.

Chemistry. 2019 May 10;25(27):6698-6702. doi: 10.1002/chem.201900329. Epub 2019 Apr 25.


Increased SLC38A4 Amino Acid Transporter Expression in Human Pancreatic α-Cells After Glucagon Receptor Inhibition.

Kim J, Dominguez Gutierrez G, Xin Y, Cavino K, Sung B, Sipos B, Kloeppel G, Gromada J, Okamoto H.

Endocrinology. 2019 May 1;160(5):979-988. doi: 10.1210/en.2019-00022.


Sweet syndrome in a patient with chronic myelogenous leukemia under dasatinib treatment.

Matsuda T, Ueda-Hayakawa I, Kambe N, Fujita S, Okamoto H.

J Dermatol. 2019 Apr 1. doi: 10.1111/1346-8138.14868. [Epub ahead of print] No abstract available.


Carboplatin, S-1 and concurrent thoracic radiotherapy for elderly patients with locally advanced non-small cell lung cancer: a multicenter Phase I/II study.

Niho S, Hosomi Y, Okamoto H, Nihei K, Tanaka H, Hida T, Umemura S, Goto K, Akimoto T, Ohe Y.

Jpn J Clin Oncol. 2019 Mar 27. pii: hyz039. doi: 10.1093/jjco/hyz039. [Epub ahead of print]


Development of a Highly Potent Analogue and a Long-Acting Analogue of Oxytocin for the Treatment of Social Impairment-Like Behaviors.

Ichinose W, Cherepanov SM, Shabalova AA, Yokoyama S, Yuhi T, Yamaguchi H, Watanabe A, Yamamoto Y, Okamoto H, Horike S, Terakawa J, Daikoku T, Watanabe M, Mano N, Higashida H, Shuto S.

J Med Chem. 2019 Apr 11;62(7):3297-3310. doi: 10.1021/acs.jmedchem.8b01691. Epub 2019 Apr 2.


Reply to: "Tracheal intubation in patients with cardiac arrest: Should we focus on success rate of intubation rather than the outcome of resuscitation?"

Okamoto H, Goto T, Hasegawa K.

Resuscitation. 2019 May;138:302-303. doi: 10.1016/j.resuscitation.2019.02.049. Epub 2019 Mar 16. No abstract available.


Hereditary leiomyomatosis and renal cell cancer syndrome in which skin biopsy enabled diagnosis.

Matsuda T, Kambe N, Ly NTM, Ueda-Hayakawa I, Yamazaki F, Ohe C, Yoshida K, Kinoshita H, Furuya M, Okamoto H.

J Dermatol. 2019 Mar 19. doi: 10.1111/1346-8138.14855. [Epub ahead of print] No abstract available.


Modeling the depolarization of space-borne lidar signals.

Sato K, Okamoto H, Ishimoto H.

Opt Express. 2019 Feb 18;27(4):A117-A132. doi: 10.1364/OE.27.00A117.


Synthesis of the extended phenacene molecules, [10]phenacene and [11]phenacene, and their performance in a field-effect transistor.

Okamoto H, Hamao S, Eguchi R, Goto H, Takabayashi Y, Yen PY, Liang LU, Chou CW, Hoffmann G, Gohda S, Sugino H, Liao YF, Ishii H, Kubozono Y.

Sci Rep. 2019 Mar 8;9(1):4009. doi: 10.1038/s41598-019-39899-4.


[On-line Adaptive Radiotherapy Using MRI-Guided Technique].

Okamoto H, Sakasai T, Nishioka S, Miura Y, Aikawa A, Kuwahara J, Iijima K, Abe Y, Igaki H, Itami J.

Igaku Butsuri. 2019;38(4):159-165. doi: 10.11323/jjmp.38.4_159. Japanese.


Assessment of the cost effectiveness of compulsory testing of introduced animals and bulk tank milk testing for bovine viral diarrhea in Japan.

Isoda N, Asano A, Ichijo M, Ohno H, Sato K, Okamoto H, Nakao S, Kato H, Saito K, Ito N, Usui A, Takayama H, Sakoda Y.

J Vet Med Sci. 2019 Apr 16;81(4):577-585. doi: 10.1292/jvms.18-0671. Epub 2019 Mar 1.


Dependence of neutrons generated by 7Li(p,n) reaction on Li thickness under free-air condition in accelerator-based boron neutron capture therapy system employing solid-state Li target.

Nakamura S, Igaki H, Okamoto H, Wakita A, Ito M, Imamichi S, Nishioka S, Iijima K, Nakayama H, Takemori M, Kobayashi K, Abe Y, Okuma K, Takahashi K, Inaba K, Murakami N, Nakayama Y, Nishio T, Masutani M, Itami J.

Phys Med. 2019 Feb;58:121-130. doi: 10.1016/j.ejmp.2019.02.010. Epub 2019 Feb 16.


A comparative analysis of clinicopathological factors between esophageal small cell and basaloid squamous cell carcinoma.

Ishida H, Kasajima A, Onodera Y, Konno T, Maruyama S, Okamoto H, Sato C, Heishi T, Sakurai T, Taniyama Y, Takahashi M, Fujishima F, Jingu K, Ishioka C, Sasano H, Kamei T.

Medicine (Baltimore). 2019 Feb;98(8):e14363. doi: 10.1097/MD.0000000000014363.


F10BINOL-derived chiral phosphoric acid-catalyzed enantioselective carbonyl-ene reaction: theoretical elucidation of stereochemical outcomes.

Kikuchi J, Aramaki H, Okamoto H, Terada M.

Chem Sci. 2018 Nov 19;10(5):1426-1433. doi: 10.1039/c8sc03587c. eCollection 2019 Feb 7.


Basophil count is a sensitive marker for clinical progression in a chronic spontaneous urticaria patient treated with omalizumab.

Kishimoto I, Kambe N, Ly NTM, Nguyen CTH, Okamoto H.

Allergol Int. 2019 Feb 18. pii: S1323-8930(19)30015-2. doi: 10.1016/j.alit.2019.02.002. [Epub ahead of print] No abstract available.


Antiosteoporotic Effects of Acer palmatum Extract on Osteoclastogenesis and Osteoblastogenesis.

Kuriya K, Nishio M, Wada S, Katsuzaki H, Nishise M, Okamoto H, Umekawa H.

J Med Food. 2019 Apr;22(4):365-373. doi: 10.1089/jmf.2018.4243. Epub 2019 Feb 20.


How does presurgical chemotherapy influence the efficiency of treatment for esophageal cancer recurrence after curative esophagectomy?

Taniyama Y, Sakurai T, Hikage M, Okamoto H, Sato C, Takaya K, Unno M, Kamei T.

Thorac Cancer. 2019 Apr;10(4):769-774. doi: 10.1111/1759-7714.12996. Epub 2019 Feb 12.


The incidence of post-intubation hypertension and association with repeated intubation attempts in the emergency department.

Inoue A, Okamoto H, Hifumi T, Goto T, Hagiwara Y, Watase H, Hasegawa K; Japanese Emergency Medicine Network Investigators.

PLoS One. 2019 Feb 11;14(2):e0212170. doi: 10.1371/journal.pone.0212170. eCollection 2019.


Guidelines for the use of cerebral oximetry by near-infrared spectroscopy in cardiovascular anesthesia: a report by the cerebrospinal Division of the Academic Committee of the Japanese Society of Cardiovascular Anesthesiologists (JSCVA).

Yoshitani K, Kawaguchi M, Ishida K, Maekawa K, Miyawaki H, Tanaka S, Uchino H, Kakinohana M, Koide Y, Yokota M, Okamoto H, Nomura M.

J Anesth. 2019 Apr;33(2):167-196. doi: 10.1007/s00540-019-02610-y. Epub 2019 Feb 8.


Very low prevalence of anti-HAV in Japan: high potential for future outbreak.

Yamamoto C, Ko K, Nagashima S, Harakawa T, Fujii T, Ohisa M, Katayama K, Takahashi K, Okamoto H, Tanaka J.

Sci Rep. 2019 Feb 6;9(1):1493. doi: 10.1038/s41598-018-37349-1.


Interleukin-13 receptor α2 is a novel marker and potential therapeutic target for human melanoma.

Okamoto H, Yoshimatsu Y, Tomizawa T, Kunita A, Takayama R, Morikawa T, Komura D, Takahashi K, Oshima T, Sato M, Komai M, Podyma-Inoue KA, Uchida H, Hamada H, Fujiu K, Ishikawa S, Fukayama M, Fukuhara T, Watabe T.

Sci Rep. 2019 Feb 4;9(1):1281. doi: 10.1038/s41598-019-39018-3.

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