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Efficacy and safety of dapagliflozin in Japanese patients with inadequately controlled type 1 diabetes (DEPICT-5): 52-week results from a randomized, open-label, phase III clinical trial.

Araki E, Watada H, Uchigata Y, Tomonaga O, Fujii H, Ohashi H, Okabe T, Asano M, Thoren F, Kim H, Yajima T, Langkilde AM.

Diabetes Obes Metab. 2019 Nov 19. doi: 10.1111/dom.13922. [Epub ahead of print]


Implantation of subcutaneous defibrillator is feasible and safe with monitored anesthesia care.

Afzal MR, Okabe T, Koppert T, Tyler J, Houmsse M, Augostini RS, Hummel JD, Kalbfleisch SJ, Iyer MH, Flores AS, Bhandary S, Dimitrova G, Elsayed-Awad H, Fiorini K, Gorelik L, Perez W, Saklayen S, Stein E, Turner K, Franklin NP, Ryu JN, Bhatt A, Weiss R, Daoud EG, Essandoh M.

Pacing Clin Electrophysiol. 2019 Nov 8. doi: 10.1111/pace.13838. [Epub ahead of print]


Development of a Novel Intraocular-Pressure-Lowering Therapy Targeting ATX.

Nagano N, Honjo M, Kawaguchi M, Nishimasu H, Nureki O, Kano K, Aoki J, Komatsu T, Okabe T, Kojima H, Nagano T, Aihara M.

Biol Pharm Bull. 2019;42(11):1926-1935. doi: 10.1248/bpb.b19-00567.


[Studies of the Various Chronic Kidney Failure Rat Models and Hemodialysis Mini-pig Model for the Evaluation of Anti-hyperphosphatemia Drugs].

Okabe T, Katoh M, Kano M, Okazaki R, Tanaka Y, Toyoda H, Ueno M.

Yakugaku Zasshi. 2019;139(11):1435-1448. doi: 10.1248/yakushi.19-00082. Japanese.


Author Correction: BiFC-based visualisation system reveals cell fusion morphology and heterokaryon incompatibility in the filamentous fungus Aspergillus oryzae.

Okabe T, Katayama T, Mo T, Mori N, Jin FJ, Fujii I, Iwashita K, Kitamoto K, Maruyama JI.

Sci Rep. 2019 Oct 31;9(1):16078. doi: 10.1038/s41598-019-52663-y.


Factors contributing to the ceiling effect of the EQ-5D-5L: an analysis of patients with prostate cancer judged "no-problems".

Murasawa H, Sugiyama T, Matsuoka Y, Okabe T, Wakumoto Y, Tanaka N, Sugimoto M, Oyama M, Fujimoto K, Horie S, Funagoshi M, Arakawa I, Noto S, Shimozuma K.

Qual Life Res. 2019 Oct 3. doi: 10.1007/s11136-019-02316-4. [Epub ahead of print]


Bankruptcy is an inevitable fate of repeated investments with leverage.

Nii M, Okabe T, Ito H, Morita S, Yasuda Y, Yoshimura J.

Sci Rep. 2019 Sep 24;9(1):13745. doi: 10.1038/s41598-019-50237-6.


Thiamine deficiency in a patient with recurrent renal cell carcinoma who developed weight loss with normal appetite and loss of energy soon after nivolumab treatment.

Onishi H, Okabe T, Uchida N, Shirotake S, Todo M, Oyama M, Ishida M.

Palliat Support Care. 2019 Sep 19:1-3. doi: 10.1017/S1478951519000658. [Epub ahead of print]


RIsk Stratification prior to lead Extraction and impact on major intraprocedural complications (RISE protocol).

Afzal MR, Daoud EG, Matre N, Shoben A, Burnside M, Gilliam C, Pinkhas D, Okabe T, Tyler J, Houmsse M, Kalbfleisch SS, Crestanello JA, Turner K, Weiss R, Hummel JD, Love CJ, Augostini RS.

J Cardiovasc Electrophysiol. 2019 Nov;30(11):2453-2459. doi: 10.1111/jce.14151. Epub 2019 Sep 23.


Toxic Flatworm Egg Plates Serve as a Possible Source of Tetrodotoxin for Pufferfish.

Okabe T, Oyama H, Kashitani M, Ishimaru Y, Suo R, Sugita H, Itoi S.

Toxins (Basel). 2019 Jul 11;11(7). pii: E402. doi: 10.3390/toxins11070402.


Grazing enhances species diversity in grassland communities.

Pulungan MA, Suzuki S, Gavina MKA, Tubay JM, Ito H, Nii M, Ichinose G, Okabe T, Ishida A, Shiyomi M, Togashi T, Yoshimura J, Morita S.

Sci Rep. 2019 Aug 1;9(1):11201. doi: 10.1038/s41598-019-47635-1.


[Association between fear of falling and activities of daily living among community-dwelling Japanese older adults].

Tomita Y, Arima K, Kawashiri SY, Tsujimoto R, Kanagae M, Mizukami S, Okabe T, Yamamoto N, Ohmachi I, Nakahara K, Nishimura T, Abe Y, Aoyagi K.

Nihon Koshu Eisei Zasshi. 2019;66(7):341-347. doi: 10.11236/jph.66.7_341. Japanese.


CHA2DS2-VASc score predicts 30-day readmission due to thromboembolic complications following cardioversion of atrial fibrillation: insights from US National Readmissions Database.

Buck B, Okabe T, Guha A, Daoud E.

J Interv Card Electrophysiol. 2019 Oct;56(1):55-61. doi: 10.1007/s10840-019-00593-0. Epub 2019 Jul 22.


Incidence of false-positive transmissions during remote rhythm monitoring with implantable loop recorders.

Afzal MR, Mease J, Koppert T, Okabe T, Tyler J, Houmsse M, Augostini RS, Weiss R, Hummel JD, Kalbfleisch SJ, Daoud EG.

Heart Rhythm. 2019 Jul 16. pii: S1547-5271(19)30656-3. doi: 10.1016/j.hrthm.2019.07.015. [Epub ahead of print]


HLA-DQ and RBFOX1 as susceptibility genes for an outbreak of hydrolyzed wheat allergy.

Noguchi E, Akiyama M, Yagami A, Hirota T, Okada Y, Kato Z, Kishikawa R, Fukutomi Y, Hide M, Morita E, Aihara M, Hiragun M, Chinuki Y, Okabe T, Ito A, Adachi A, Fukunaga A, Kubota Y, Aoki T, Aoki Y, Nishioka K, Adachi T, Kanazawa N, Miyazawa H, Sakai H, Kozuka T, Kitamura H, Hashizume H, Kanegane C, Masuda K, Sugiyama K, Tokuda R, Furuta J, Higashimoto I, Kato A, Seishima M, Tajiri A, Tomura A, Taniguchi H, Kojima H, Tanaka H, Sakai A, Morii W, Nakamura M, Kamatani Y, Takahashi A, Kubo M, Tamari M, Saito H, Matsunaga K.

J Allergy Clin Immunol. 2019 Nov;144(5):1354-1363. doi: 10.1016/j.jaci.2019.06.034. Epub 2019 Jul 10.


A novel technique to diagnose non-melanoma skin cancer by thermal conductivity measurements: Correlations with cancer stromal factors.

Fujimura T, Okabe T, Tanita K, Sato Y, Lyu C, Kambayashi Y, Maruyama S, Aiba S.

Exp Dermatol. 2019 Sep;28(9):1029-1035. doi: 10.1111/exd.13997. Epub 2019 Aug 12.


Prevalence of antimicrobial use and active healthcare-associated infections in acute care hospitals: a multicentre prevalence survey in Japan.

Komagamine J, Yabuki T, Kobayashi M, Okabe T.

BMJ Open. 2019 Jun 28;9(6):e027604. doi: 10.1136/bmjopen-2018-027604.


Incidence and outcomes of systemic infections in patients with leadless pacemakers: Data from the Micra IDE study.

El-Chami MF, Soejima K, Piccini JP, Reynolds D, Ritter P, Okabe T, Friedman PA, Cha YM, Stromberg K, Holbrook R, Fagan DH, Roberts PR.

Pacing Clin Electrophysiol. 2019 Aug;42(8):1105-1110. doi: 10.1111/pace.13752. Epub 2019 Jul 2.


Increased risk of hematoma with uninterrupted warfarin in patients undergoing implantation of subcutaneous implantable cardioverter defibrillator.

Evenson C, Saour B, Afzal MR, Knight B, Okabe T, Weiss R.

Pacing Clin Electrophysiol. 2019 Aug;42(8):1111-1114. doi: 10.1111/pace.13754. Epub 2019 Jul 7.


Bilateral Necrotizing Herpes Simplex Keratitis in an Immunocompetent Patient With Genetic Analysis of Herpes Simplex Virus 1.

Yoshida M, Hosogai M, Yokokura S, Sato K, Hariya T, Kobayashi W, Okabe T, Todokoro D, Nakazawa T.

Cornea. 2019 Sep;38(9):1185-1188. doi: 10.1097/ICO.0000000000002026.


Pirfenidone attenuates lung fibrotic fibroblast responses to transforming growth factor-β1.

Jin J, Togo S, Kadoya K, Tulafu M, Namba Y, Iwai M, Watanabe J, Nagahama K, Okabe T, Hidayat M, Kodama Y, Kitamura H, Ogura T, Kitamura N, Ikeo K, Sasaki S, Tominaga S, Takahashi K.

Respir Res. 2019 Jun 11;20(1):119. doi: 10.1186/s12931-019-1093-z.


Hierarchical Gaussian Descriptors with Application to Person Re-Identification.

Matsukawa T, Okabe T, Suzuki E, Sato Y.

IEEE Trans Pattern Anal Mach Intell. 2019 May 3. doi: 10.1109/TPAMI.2019.2914686. [Epub ahead of print]


Effects of pharmacist participation in chronic kidney disease (CKD) network and CKD manual distribution on drug-related kidney injury.

Yamamoto T, Nakayama I, Kawakatsu Y, Yamamoto T, Ishigami N, Watanuki K, Okabe T, Yokoyama H.

Pharmacoepidemiol Drug Saf. 2019 Jun;28(6):887-896. doi: 10.1002/pds.4787. Epub 2019 Apr 30.


Health utility and health-related quality of life of Japanese prostate cancer patients according to progression status measured using EQ-5D-5L and FACT-P.

Murasawa H, Sugiyama T, Matsuoka Y, Okabe T, Hino A, Tanaka N, Sugimoto M, Oyama M, Fujimoto K, Horie S, Noto S, Shimozuma K.

Qual Life Res. 2019 Sep;28(9):2383-2391. doi: 10.1007/s11136-019-02184-y. Epub 2019 Apr 25.


Safety and Efficacy of Tolvaptan for the Prevention of Contrast-Induced Acute Kidney Injury in Patients with Heart Failure and Chronic Kidney Disease.

Yamashita K, Igawa W, Ono M, Kido T, Okabe T, Yamamoto MH, Amemiya K, Isomura N, Araki H, Ochiai M.

Kidney Dis (Basel). 2019 Mar;5(2):100-106. doi: 10.1159/000494724. Epub 2018 Nov 29.


Relationship between bone turnover markers and the heel stiffness index measured by quantitative ultrasound in post-menopausal Japanese women.

Nishimura T, Arima K, Abe Y, Kanagae M, Mizukami S, Okabe T, Tomita Y, Goto H, Hasegawa M, Sou Y, Horiguchi I, Aoyagi K.

Ann Hum Biol. 2019 Jun;46(4):330-334. doi: 10.1080/03014460.2019.1607552.


Effect of cutting balloon after rotational atherectomy in severely calcified coronary artery lesions as assessed by optical coherence tomography.

Amemiya K, Yamamoto MH, Maehara A, Oyama Y, Igawa W, Ono M, Kido T, Ebara S, Okabe T, Yamashita K, Hoshimoto K, Saito S, Yakushiji T, Isomura N, Araki H, Mintz GS, Ochiai M.

Catheter Cardiovasc Interv. 2019 Apr 11. doi: 10.1002/ccd.28278. [Epub ahead of print]


Impact of recanalization of chronic total occlusion on left ventricular electrical remodeling.

Yamashita K, Igawa W, Ono M, Kido T, Okabe T, Isomura N, Araki H, Ochiai M.

Pacing Clin Electrophysiol. 2019 Jun;42(6):712-721. doi: 10.1111/pace.13691. Epub 2019 Apr 25.


The unified rule of phyllotaxis explaining both spiral and non-spiral arrangements.

Okabe T, Ishida A, Yoshimura J.

J R Soc Interface. 2019 Feb 28;16(151):20180850. doi: 10.1098/rsif.2018.0850.


Specific Features of Fibrotic Lung Fibroblasts Highly Sensitive to Fibrotic Processes Mediated via TGF-β-ERK5 Interaction.

Kadoya K, Togo S, Tulafu M, Namba Y, Iwai M, Watanabe J, Okabe T, Jin J, Kodama Y, Kitamura H, Ogura T, Kitamura N, Ikeo K, Takeda T, Kondo N, Takahashi K.

Cell Physiol Biochem. 2019;52(4):822-837. doi: 10.33594/000000057.


First-in-human clinical study of novel technique to diagnose malignant melanoma via thermal conductivity measurements.

Okabe T, Fujimura T, Okajima J, Kambayashi Y, Aiba S, Maruyama S.

Sci Rep. 2019 Mar 7;9(1):3853. doi: 10.1038/s41598-019-40444-6.


Oxytocin/vasopressin-like peptide inotocin regulates cuticular hydrocarbon synthesis and water balancing in ants.

Koto A, Motoyama N, Tahara H, McGregor S, Moriyama M, Okabe T, Miura M, Keller L.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5597-5606. doi: 10.1073/pnas.1817788116. Epub 2019 Mar 6.


Usefulness of Implementing Comprehensive Pharmaceutical Care for Metastatic Renal Cell Carcinoma Outpatients Treated with Pazopanib.

Todo M, Shirotake S, Nishimoto K, Yasumizu Y, Kaneko G, Kondo H, Okabe T, Makabe H, Oyama M.

Anticancer Res. 2019 Feb;39(2):999-1004. doi: 10.21873/anticanres.13205.


Early tumor shrinkage as a predictive factor of metastatic renal cell carcinoma in molecular targeted therapy: A single institutional study.

Shirotake S, Kondo H, Okabe T, Makino S, Araki R, Komatsuda A, Kaneko G, Nishimoto K, Oyama M.

Mol Clin Oncol. 2019 Jan;10(1):125-131. doi: 10.3892/mco.2018.1762. Epub 2018 Nov 12.


Toxicologic Pathology Forum: Current Status on the Use of Animal Models of Human Disease in the Pharmaceutical Industry in Japan in Nonclinical Safety Assessment-Opinion Paper.

Tomohiro M, Okabe T, Kimura Y, Kinoshita K, Maeda M, Mitobe Y, Motoyama K, Yonezawa R, Sasaki S, Fujiwara M, Watanabe K.

Toxicol Pathol. 2019 Feb;47(2):108-120. doi: 10.1177/0192623318816669. Epub 2019 Jan 13.


Marked T wave abnormality after accessory pathway ablation.

Okabe T, Weiss R, Hummel JD, Kalbfleisch SJ.

J Cardiovasc Electrophysiol. 2019 Apr;30(4):622-623. doi: 10.1111/jce.13830. Epub 2019 Jan 4. No abstract available.


Pediatric oncologic emergencies: Clinical and imaging review for pediatricians.

Handa A, Nozaki T, Makidono A, Okabe T, Morita Y, Fujita K, Matsusako M, Kono T, Kurihara Y, Hasegawa D, Kumamoto T, Ogawa C, Yuza Y, Manabe A.

Pediatr Int. 2019 Feb;61(2):122-139. doi: 10.1111/ped.13755. Epub 2019 Feb 7. Review.


Porous diaphragm syndrome with recurrent thymoma.

Ota T, Hasegawa Y, Okabe T, Okimura A, Fukuoka M.

Respirol Case Rep. 2018 Nov 28;7(2):e00391. doi: 10.1002/rcr2.391. eCollection 2019 Feb.


A Case of Renal Oncocytoma with Renal Venous Tumor Thrombus.

Kondo H, Okabe T, Okada Y, Hasebe T, Shirotake S, Oyama M, Nishimoto K.

Keio J Med. 2019 Jun 25;68(2):39-41. doi: 10.2302/kjm.2017-0012-CR. Epub 2018 Nov 23.


Reply to "The electroencephalogram in syncope".

Izumi M, Okabe T, Komura M, Hayashi Y.

J Gen Fam Med. 2018 Oct 24;19(6):227. doi: 10.1002/jgf2.217. eCollection 2018 Nov. No abstract available.


Inexpensive High-Throughput Screening of Kinase Inhibitors Using One-Step Enzyme-Coupled Fluorescence Assay for ADP Detection.

Imamura RM, Kumagai K, Nakano H, Okabe T, Nagano T, Kojima H.

SLAS Discov. 2019 Mar;24(3):284-294. doi: 10.1177/2472555218810139. Epub 2018 Nov 12.


Comprehensive strategy to reduce the incidence of lead dislodgement for cardiac implantable electronic devices.

Afzal MR, Horner S, Matre NB, Blake P, Dunham K, Pinkhas D, Okabe T, Tyler J, Houmsse M, Kalbfleisch SJ, Weiss R, Hummel JD, Daoud EG, Augostini RS.

Pacing Clin Electrophysiol. 2019 Jan;42(1):58-62. doi: 10.1111/pace.13544. Epub 2018 Nov 29.


Development of Pin1 inhibitors and their potential as therapeutic agents.

Nakatsu Y, Matsunaga Y, Ueda K, Yamamotoya T, Inoue Y, Inoue MK, Mizuno Y, Kushiyama A, Ono H, Fujishiro M, Ito H, Okabe T, Asano T.

Curr Med Chem. 2018 Nov 5. doi: 10.2174/0929867325666181105120911. [Epub ahead of print]


Association of Epicardial Adipose Tissue Volume and Total Coronary Plaque Burden in Patients with Coronary Artery Disease.

Yamashita K, Yamamoto MH, Igawa W, Ono M, Kido T, Ebara S, Okabe T, Saito S, Amemiya K, Isomura N, Araki H, Ochiai M.

Int Heart J. 2018 Nov 28;59(6):1219-1226. doi: 10.1536/ihj.17-709. Epub 2018 Oct 25.


Novel indole and benzothiophene ring derivatives showing differential modulatory activity against human epithelial sodium channel subunits, ENaC β and γ.

Kasahara Y, Sakurai T, Matsuda R, Narukawa M, Yasuoka A, Mori N, Watanabe H, Okabe T, Kojima H, Abe K, Misaka T, Asakura T.

Biosci Biotechnol Biochem. 2019 Feb;83(2):243-250. doi: 10.1080/09168451.2018.1533802. Epub 2018 Oct 21.


Clinical experience with wearable cardioverter defibrillators at a tertiary electrophysiology program.

Bossory L, Schubert S, Afzal MR, Weiss R, Tyler J, Kalbfleisch S, Augostini R, Hummel J, Okabe T, Daoud EG, Houmsse M.

Pacing Clin Electrophysiol. 2018 Nov;41(11):1491-1494. doi: 10.1111/pace.13491. Epub 2018 Sep 29.


[Occurrence of acquired factor V inhibitor during antibiotic therapy for a surgical wound infection].

Okabe T, Ueno H, Fujita S, Kagoo T, Boku S, Yano T, Yokoyama A.

Rinsho Ketsueki. 2018;59(8):1007-1011. doi: 10.11406/rinketsu.59.1007. Japanese.


Serum zinc concentration in patients with acute myocardial infarction in percutaneous coronary intervention era.

Okabe T, Yakushiji T, Shimazu S, Saito J, Kimura T, Oyama Y, Igawa W, Ono M, Kido T, Ebara S, Yamashita K, Yamamoto MH, Amemiya K, Isomura N, Ochiai M.

PLoS One. 2018 Aug 30;13(8):e0203074. doi: 10.1371/journal.pone.0203074. eCollection 2018.


A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.

Tsuburaya N, Homma K, Higuchi T, Balia A, Yamakoshi H, Shibata N, Nakamura S, Nakagawa H, Ikeda SI, Umezawa N, Kato N, Yokoshima S, Shibuya M, Shimonishi M, Kojima H, Okabe T, Nagano T, Naguro I, Imamura K, Inoue H, Fujisawa T, Ichijo H.

Nat Commun. 2018 Jul 10;9(1):2668. doi: 10.1038/s41467-018-05127-2.


Feasibility of concomitant vacuum-assisted removal of lead-related vegetations and cardiac implantable electronic device extraction.

Godara H, Jia KQ, Augostini RS, Houmsse M, Okabe T, Hummel JD, Weiss R, Kalbfleisch SJ, Afzal MR, Badin A, Cavalcanti R, Franco DA, Tyler J, Daoud EG.

J Cardiovasc Electrophysiol. 2018 Oct;29(10):1460-1466. doi: 10.1111/jce.13692. Epub 2018 Jul 20.


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