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Items: 1 to 50 of 68

1.

Presence of Giardia lamblia in stools of six- to 18-month old asymptomatic Malawians is associated with children's growth failure.

Lehto KM, Fan YM, Oikarinen S, Nurminen N, Hallamaa L, Juuti R, Mangani C, Maleta K, Hyöty H, Ashorn P.

Acta Paediatr. 2019 Apr 30. doi: 10.1111/apa.14832. [Epub ahead of print]

PMID:
31038225
2.

High prevalence of selected viruses and parasites and their predictors in Malawian children.

Fan YM, Oikarinen S, Lehto KM, Nurminen N, Juuti R, Mangani C, Maleta K, Hyöty H, Ashorn P.

Epidemiol Infect. 2019 Jan;147:e90. doi: 10.1017/S0950268819000025.

3.

Rhinoviruses in infancy and risk of immunoglobulin E sensitization.

Korhonen L, Oikarinen S, Lehtonen J, Mustonen N, Tyni I, Niemelä O, Honkanen H, Huhtala H, Ilonen J, Hämäläinen AM, Peet A, Tillmann V, Siljander H, Knip M, Lönnrot M, Hyöty H; DIABIMMUNE Study Group.

J Med Virol. 2019 Mar 13. doi: 10.1002/jmv.25455. [Epub ahead of print]

PMID:
30866076
4.

Molecular epidemiology of enteroviruses in young children at increased risk of type 1 diabetes.

Sioofy-Khojine AB, Oikarinen S, Honkanen H, Huhtala H, Lehtonen JP, Briese T, Hyöty H; TEDDY Study Group.

PLoS One. 2018 Sep 7;13(9):e0201959. doi: 10.1371/journal.pone.0201959. eCollection 2018.

5.

Bioinformatics Assembling and Assessment of Novel Coxsackievirus B1 Genome.

Lin J, Kimura BY, Oikarinen S, Nykter M.

Methods Mol Biol. 2018;1838:261-272. doi: 10.1007/978-1-4939-8682-8_18.

PMID:
30129002
6.

Strain-Level Analysis of Mother-to-Child Bacterial Transmission during the First Few Months of Life.

Yassour M, Jason E, Hogstrom LJ, Arthur TD, Tripathi S, Siljander H, Selvenius J, Oikarinen S, Hyöty H, Virtanen SM, Ilonen J, Ferretti P, Pasolli E, Tett A, Asnicar F, Segata N, Vlamakis H, Lander ES, Huttenhower C, Knip M, Xavier RJ.

Cell Host Microbe. 2018 Jul 11;24(1):146-154.e4. doi: 10.1016/j.chom.2018.06.007.

PMID:
30001517
7.

Nature-derived microbiota exposure as a novel immunomodulatory approach.

Nurminen N, Lin J, Grönroos M, Puhakka R, Kramna L, Vari HK, Viskari H, Oikarinen S, Roslund M, Parajuli A, Tyni I, Cinek O, Laitinen O, Hyöty H, Sinkkonen A.

Future Microbiol. 2018 Jun 1;13:737-744. doi: 10.2217/fmb-2017-0286. Epub 2018 May 17.

PMID:
29771153
8.

Coxsackievirus B1 infections are associated with the initiation of insulin-driven autoimmunity that progresses to type 1 diabetes.

Sioofy-Khojine AB, Lehtonen J, Nurminen N, Laitinen OH, Oikarinen S, Huhtala H, Pakkanen O, Ruokoranta T, Hankaniemi MM, Toppari J, Vähä-Mäkilä M, Ilonen J, Veijola R, Knip M, Hyöty H.

Diabetologia. 2018 May;61(5):1193-1202. doi: 10.1007/s00125-018-4561-y. Epub 2018 Feb 5.

PMID:
29404673
9.

A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes.

Stone VM, Hankaniemi MM, Svedin E, Sioofy-Khojine A, Oikarinen S, Hyöty H, Laitinen OH, Hytönen VP, Flodström-Tullberg M.

Diabetologia. 2018 Feb;61(2):476-481. doi: 10.1007/s00125-017-4492-z. Epub 2017 Nov 18.

10.

Enterovirus-associated changes in blood transcriptomic profiles of children with genetic susceptibility to type 1 diabetes.

Lietzen N, An LTT, Jaakkola MK, Kallionpää H, Oikarinen S, Mykkänen J, Knip M, Veijola R, Ilonen J, Toppari J, Hyöty H, Lahesmaa R, Elo LL.

Diabetologia. 2018 Feb;61(2):381-388. doi: 10.1007/s00125-017-4460-7. Epub 2017 Nov 8.

11.

Live attenuated enterovirus vaccine (OPV) is not associated with islet autoimmunity in children with genetic susceptibility to type 1 diabetes: prospective cohort study.

Viskari H, Oikarinen S, Hoppu S, Vuorinen T, Huhtala H, Toppari J, Veijola R, Ilonen J, Knip M, Hyöty H.

Diabetologia. 2018 Jan;61(1):203-209. doi: 10.1007/s00125-017-4410-4. Epub 2017 Sep 2.

PMID:
28866779
12.

Next-Generation Sequencing Combined with Specific PCR Assays To Determine the Bacterial 16S rRNA Gene Profiles of Middle Ear Fluid Collected from Children with Acute Otitis Media.

Sillanpää S, Kramna L, Oikarinen S, Sipilä M, Rautiainen M, Aittoniemi J, Laranne J, Hyöty H, Cinek O.

mSphere. 2017 Mar 22;2(2). pii: e00006-17. doi: 10.1128/mSphere.00006-17. eCollection 2017 Mar-Apr.

13.

Detection of enteroviruses in stools precedes islet autoimmunity by several months: possible evidence for slowly operating mechanisms in virus-induced autoimmunity.

Honkanen H, Oikarinen S, Nurminen N, Laitinen OH, Huhtala H, Lehtonen J, Ruokoranta T, Hankaniemi MM, Lecouturier V, Almond JW, Tauriainen S, Simell O, Ilonen J, Veijola R, Viskari H, Knip M, Hyöty H.

Diabetologia. 2017 Mar;60(3):424-431. doi: 10.1007/s00125-016-4177-z. Epub 2017 Jan 9.

PMID:
28070615
14.

Imbalance of bacteriome profiles within the Finnish Diabetes Prediction and Prevention study: Parallel use of 16S profiling and virome sequencing in stool samples from children with islet autoimmunity and matched controls.

Cinek O, Kramna L, Lin J, Oikarinen S, Kolarova K, Ilonen J, Simell O, Veijola R, Autio R, Hyöty H.

Pediatr Diabetes. 2017 Nov;18(7):588-598. doi: 10.1111/pedi.12468. Epub 2016 Nov 17.

PMID:
27860030
15.

Human enterovirus and rhinovirus infections are associated with otitis media in a prospective birth cohort study.

Seppälä E, Sillanpää S, Nurminen N, Huhtala H, Toppari J, Ilonen J, Veijola R, Knip M, Sipilä M, Laranne J, Oikarinen S, Hyöty H.

J Clin Virol. 2016 Dec;85:1-6. doi: 10.1016/j.jcv.2016.10.010. Epub 2016 Oct 20.

PMID:
27780081
16.

Moraxella catarrhalis Might Be More Common than Expected in Acute Otitis Media in Young Finnish Children.

Sillanpää S, Oikarinen S, Sipilä M, Kramna L, Rautiainen M, Huhtala H, Aittoniemi J, Laranne J, Hyöty H, Cinek O.

J Clin Microbiol. 2016 Sep;54(9):2373-9. doi: 10.1128/JCM.01146-16. Epub 2016 Jul 13.

17.

Relative sensitivity of immunohistochemistry, multiple reaction monitoring mass spectrometry, in situ hybridization and PCR to detect Coxsackievirus B1 in A549 cells.

Laiho JE, Oikarinen M, Richardson SJ, Frisk G, Nyalwidhe J, Burch TC, Morris MA, Oikarinen S, Pugliese A, Dotta F, Campbell-Thompson M, Nadler J, Morgan NG, Hyöty H; JDRF nPOD-Virus Group.

J Clin Virol. 2016 Apr;77:21-8. doi: 10.1016/j.jcv.2016.01.015. Epub 2016 Feb 2.

18.

Application of bioinformatics in probe design enables detection of enteroviruses on different taxonomic levels by advanced in situ hybridization technology.

Laiho JE, Oikarinen S, Oikarinen M, Larsson PG, Stone VM, Hober D, Oberste S, Flodström-Tullberg M, Isola J, Hyöty H.

J Clin Virol. 2015 Aug;69:165-71. doi: 10.1016/j.jcv.2015.06.085. Epub 2015 Jun 23.

PMID:
26209400
19.

Multiple consecutive norovirus infections in the first 2 years of life.

Blazevic V, Malm M, Salminen M, Oikarinen S, Hyöty H, Veijola R, Vesikari T.

Eur J Pediatr. 2015 Dec;174(12):1679-83. doi: 10.1007/s00431-015-2591-8. Epub 2015 Jul 9.

20.

High-throughput multiplex quantitative polymerase chain reaction method for Giardia lamblia and Cryptosporidium species detection in stool samples.

Nurminen N, Juuti R, Oikarinen S, Fan YM, Lehto KM, Mangani C, Maleta K, Ashorn P, Hyöty H.

Am J Trop Med Hyg. 2015 Jun;92(6):1222-6. doi: 10.4269/ajtmh.15-0054. Epub 2015 Apr 27.

21.

Gut virome sequencing in children with early islet autoimmunity.

Kramná L, Kolářová K, Oikarinen S, Pursiheimo JP, Ilonen J, Simell O, Knip M, Veijola R, Hyöty H, Cinek O.

Diabetes Care. 2015 May;38(5):930-3. doi: 10.2337/dc14-2490. Epub 2015 Feb 12.

PMID:
25678103
22.

Human parechovirus as a minor cause of acute otitis media in children.

Sillanpää S, Oikarinen S, Sipilä M, Seppälä E, Nurminen N, Rautiainen M, Laranne J, Hyöty H.

J Clin Virol. 2015 Jan;62:106-9. doi: 10.1016/j.jcv.2014.11.002. Epub 2014 Nov 8.

PMID:
25464964
23.

Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes.

Krogvold L, Edwin B, Buanes T, Frisk G, Skog O, Anagandula M, Korsgren O, Undlien D, Eike MC, Richardson SJ, Leete P, Morgan NG, Oikarinen S, Oikarinen M, Laiho JE, Hyöty H, Ludvigsson J, Hanssen KF, Dahl-Jørgensen K.

Diabetes. 2015 May;64(5):1682-7. doi: 10.2337/db14-1370. Epub 2014 Nov 24.

24.

Enterovirus RNA in longitudinal blood samples and risk of islet autoimmunity in children with a high genetic risk of type 1 diabetes: the MIDIA study.

Cinek O, Stene LC, Kramna L, Tapia G, Oikarinen S, Witsø E, Rasmussen T, Torjesen PA, Hyöty H, Rønningen KS.

Diabetologia. 2014 Oct;57(10):2193-200. doi: 10.1007/s00125-014-3327-4. Epub 2014 Jul 23.

PMID:
25047648
25.

Coxsackievirus B1 reveals strain specific differences in plasmacytoid dendritic cell mediated immunogenicity.

Hämäläinen S, Nurminen N, Ahlfors H, Oikarinen S, Sioofy-Khojine AB, Frisk G, Oberste MS, Lahesmaa R, Pesu M, Hyöty H.

J Med Virol. 2014 Aug;86(8):1412-20. doi: 10.1002/jmv.23903. Epub 2014 Feb 20.

PMID:
24616040
26.

Coxsackievirus B3 VLPs purified by ion exchange chromatography elicit strong immune responses in mice.

Koho T, Koivunen MR, Oikarinen S, Kummola L, Mäkinen S, Mähönen AJ, Sioofy-Khojine A, Marjomäki V, Kazmertsuk A, Junttila I, Kulomaa MS, Hyöty H, Hytönen VP, Laitinen OH.

Antiviral Res. 2014 Apr;104:93-101. doi: 10.1016/j.antiviral.2014.01.013. Epub 2014 Jan 28.

PMID:
24485896
27.

Virus antibody survey in different European populations indicates risk association between coxsackievirus B1 and type 1 diabetes.

Oikarinen S, Tauriainen S, Hober D, Lucas B, Vazeou A, Sioofy-Khojine A, Bozas E, Muir P, Honkanen H, Ilonen J, Knip M, Keskinen P, Saha MT, Huhtala H, Stanway G, Bartsocas C, Ludvigsson J, Taylor K, Hyöty H; VirDiab Study Group.

Diabetes. 2014 Feb;63(2):655-62. doi: 10.2337/db13-0620. Epub 2013 Sep 5.

28.

Coxsackievirus B1 is associated with induction of β-cell autoimmunity that portends type 1 diabetes.

Laitinen OH, Honkanen H, Pakkanen O, Oikarinen S, Hankaniemi MM, Huhtala H, Ruokoranta T, Lecouturier V, André P, Harju R, Virtanen SM, Lehtonen J, Almond JW, Simell T, Simell O, Ilonen J, Veijola R, Knip M, Hyöty H.

Diabetes. 2014 Feb;63(2):446-55. doi: 10.2337/db13-0619. Epub 2013 Aug 23.

29.

Human parechovirus and the risk of type 1 diabetes.

Kolehmainen P, Koskiniemi M, Oikarinen S, Veijola R, Simell O, Ilonen J, Knip M, Hyöty H, Tauriainen S.

J Med Virol. 2013 Sep;85(9):1619-23. doi: 10.1002/jmv.23659.

PMID:
23852688
30.

Is alcoholic pancreatitis associated with enteroviral infection?

Khan J, Nordback I, Seppänen H, Lappalainen-Lehto R, Järvinen S, Oikarinen S, Tauriainen S, Räty S, Hyöty H, Sand J.

World J Gastroenterol. 2013 Jun 28;19(24):3819-23. doi: 10.3748/wjg.v19.i24.3819.

31.

Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY.

Vehik K, Fiske SW, Logan CA, Agardh D, Cilio CM, Hagopian W, Simell O, Roivainen M, She JX, Briese T, Oikarinen S, Hyoty H, Ziegler AG, Rewers M, Lernmark A, Akolkar B, Krischer JP, Burkhardt BR; TEDDY Study Group.

Diabetes Metab Res Rev. 2013 Oct;29(7):557-67. doi: 10.1002/dmrr.2427.

32.

Human rhinoviruses including group C are common in stool samples of young Finnish children.

Honkanen H, Oikarinen S, Peltonen P, Simell O, Ilonen J, Veijola R, Knip M, Hyöty H.

J Clin Virol. 2013 Mar;56(3):250-4. doi: 10.1016/j.jcv.2012.11.020. Epub 2012 Dec 27.

PMID:
23273491
33.

Human enterovirus 71 strains in the background population and in hospital patients in Finland.

Honkanen H, Oikarinen S, Pakkanen O, Ruokoranta T, Pulkki MM, Laitinen OH, Tauriainen S, Korpela S, Lappalainen M, Vuorinen T, Haapala AM, Veijola R, Simell O, Ilonen J, Knip M, Hyöty H.

J Clin Virol. 2013 Apr;56(4):348-53. doi: 10.1016/j.jcv.2012.11.018. Epub 2012 Dec 21.

PMID:
23261080
34.

Human parechoviruses are frequently detected in stool of healthy Finnish children.

Kolehmainen P, Oikarinen S, Koskiniemi M, Simell O, Ilonen J, Knip M, Hyöty H, Tauriainen S.

J Clin Virol. 2012 Jun;54(2):156-61. doi: 10.1016/j.jcv.2012.02.006. Epub 2012 Mar 8.

PMID:
22406272
35.

Type 1 diabetes is associated with enterovirus infection in gut mucosa.

Oikarinen M, Tauriainen S, Oikarinen S, Honkanen T, Collin P, Rantala I, Mäki M, Kaukinen K, Hyöty H.

Diabetes. 2012 Mar;61(3):687-91. doi: 10.2337/db11-1157. Epub 2012 Feb 7.

36.

Virus infections as potential targets of preventive treatments for type 1 diabetes.

Nurminen N, Oikarinen S, Hyöty H.

Rev Diabet Stud. 2012 Winter;9(4):260-71. doi: 10.1900/RDS.2012.9.260. Epub 2012 Dec 28. Review.

37.

Enterovirus infections in young infants: are children still protected by maternal antibodies?

Salur L, Oikarinen S, Tauriainen S, Mandel M, Hyöty H, Uibo R.

Hum Vaccin. 2011 Sep;7(9):966-71. doi: 10.4161/hv.7.9.16082. Epub 2011 Sep 1.

PMID:
21860257
38.

Enterovirus RNA in blood is linked to the development of type 1 diabetes.

Oikarinen S, Martiskainen M, Tauriainen S, Huhtala H, Ilonen J, Veijola R, Simell O, Knip M, Hyöty H.

Diabetes. 2011 Jan;60(1):276-9. doi: 10.2337/db10-0186. Epub 2010 Oct 13.

39.

Low zinc in drinking water is associated with the risk of type 1 diabetes in children.

Samuelsson U, Oikarinen S, Hyöty H, Ludvigsson J.

Pediatr Diabetes. 2011 May;12(3 Pt 1):156-64. doi: 10.1111/j.1399-5448.2010.00678.x. Epub 2010 Sep 7.

PMID:
20920146
40.

Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY).

Stene LC, Oikarinen S, Hyöty H, Barriga KJ, Norris JM, Klingensmith G, Hutton JC, Erlich HA, Eisenbarth GS, Rewers M.

Diabetes. 2010 Dec;59(12):3174-80. doi: 10.2337/db10-0866. Epub 2010 Sep 21.

41.

Enteroviruses in the pathogenesis of type 1 diabetes.

Tauriainen S, Oikarinen S, Oikarinen M, Hyöty H.

Semin Immunopathol. 2011 Jan;33(1):45-55. doi: 10.1007/s00281-010-0207-y. Epub 2010 Apr 28. Review.

PMID:
20424841
42.

Genetic mapping of Mom5, a novel modifier of Apc(Min)-induced intestinal tumorigenesis.

Oikarinen SI, Cleveland AG, Cork KM, Bynoté KK, Rafter JJ, Gustafsson JA, Mutanen M, Gould KA.

Carcinogenesis. 2009 Sep;30(9):1591-6. doi: 10.1093/carcin/bgp159. Epub 2009 Jul 2.

PMID:
19574546
43.

Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice.

Cleveland AG, Oikarinen SI, Bynoté KK, Marttinen M, Rafter JJ, Gustafsson JA, Roy SK, Pitot HC, Korach KS, Lubahn DB, Mutanen M, Gould KA.

Carcinogenesis. 2009 Sep;30(9):1581-90. doi: 10.1093/carcin/bgp132. Epub 2009 Jun 11.

44.

Evolution and conservation in human parechovirus genomes.

Williams CH, Panayiotou M, Girling GD, Peard CI, Oikarinen S, Hyöty H, Stanway G.

J Gen Virol. 2009 Jul;90(Pt 7):1702-12. doi: 10.1099/vir.0.008813-0. Epub 2009 Mar 4.

PMID:
19264613
45.

PCR inhibition in stool samples in relation to age of infants.

Oikarinen S, Tauriainen S, Viskari H, Simell O, Knip M, Virtanen S, Hyöty H.

J Clin Virol. 2009 Mar;44(3):211-4. doi: 10.1016/j.jcv.2008.12.017. Epub 2009 Feb 3.

PMID:
19196549
46.

Analysis of pancreas tissue in a child positive for islet cell antibodies.

Oikarinen M, Tauriainen S, Honkanen T, Vuori K, Karhunen P, Vasama-Nolvi C, Oikarinen S, Verbeke C, Blair GE, Rantala I, Ilonen J, Simell O, Knip M, Hyöty H.

Diabetologia. 2008 Oct;51(10):1796-802. doi: 10.1007/s00125-008-1107-8. Epub 2008 Aug 12.

PMID:
18696046
47.

Maternal enterovirus infection during pregnancy as a risk factor in offspring diagnosed with type 1 diabetes between 15 and 30 years of age.

Elfving M, Svensson J, Oikarinen S, Jonsson B, Olofsson P, Sundkvist G, Lindberg B, Lernmark A, Hyöty H, Ivarsson SA.

Exp Diabetes Res. 2008;2008:271958. doi: 10.1155/2008/271958.

48.

Berries as chemopreventive dietary constituents--a mechanistic approach with the ApcMin/+ mouse.

Mutanen M, Pajari AM, Paivarinta E, Misikangas M, Rajakangas J, Marttinen M, Oikarinen S.

Asia Pac J Clin Nutr. 2008;17 Suppl 1:123-5. Review.

49.

Temporal relationship between human parechovirus 1 infection and otitis media in young children.

Tauriainen S, Oikarinen S, Taimen K, Laranne J, Sipilä M, Lönnrot M, Ilonen J, Simell O, Knip M, Hyöty H.

J Infect Dis. 2008 Jul 1;198(1):35-40. doi: 10.1086/588677.

PMID:
18462136
50.

Detection of enteroviruses in the intestine of type 1 diabetic patients.

Oikarinen M, Tauriainen S, Honkanen T, Oikarinen S, Vuori K, Kaukinen K, Rantala I, Mäki M, Hyöty H.

Clin Exp Immunol. 2008 Jan;151(1):71-5. Epub 2007 Nov 7.

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