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Items: 15


Detection and localization of viral infection in the pancreas of patients with type 1 diabetes using short fluorescently-labelled oligonucleotide probes.

Busse N, Paroni F, Richardson SJ, Laiho JE, Oikarinen M, Frisk G, Hyöty H, de Koning E, Morgan NG, Maedler K.

Oncotarget. 2017 Feb 21;8(8):12620-12636. doi: 10.18632/oncotarget.14896.


Relative sensitivity of immunohistochemistry, multiple reaction monitoring mass spectrometry, in situ hybridization and PCR to detect Coxsackievirus B1 in A549 cells.

Laiho JE, Oikarinen M, Richardson SJ, Frisk G, Nyalwidhe J, Burch TC, Morris MA, Oikarinen S, Pugliese A, Dotta F, Campbell-Thompson M, Nadler J, Morgan NG, Hyöty H; JDRF nPOD-Virus Group.

J Clin Virol. 2016 Apr;77:21-8. doi: 10.1016/j.jcv.2016.01.015. Epub 2016 Feb 2.


Application of bioinformatics in probe design enables detection of enteroviruses on different taxonomic levels by advanced in situ hybridization technology.

Laiho JE, Oikarinen S, Oikarinen M, Larsson PG, Stone VM, Hober D, Oberste S, Flodström-Tullberg M, Isola J, Hyöty H.

J Clin Virol. 2015 Aug;69:165-71. doi: 10.1016/j.jcv.2015.06.085. Epub 2015 Jun 23.


Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes.

Krogvold L, Edwin B, Buanes T, Frisk G, Skog O, Anagandula M, Korsgren O, Undlien D, Eike MC, Richardson SJ, Leete P, Morgan NG, Oikarinen S, Oikarinen M, Laiho JE, Hyöty H, Ludvigsson J, Hanssen KF, Dahl-Jørgensen K.

Diabetes. 2015 May;64(5):1682-7. doi: 10.2337/db14-1370. Epub 2014 Nov 24.


A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models.

Larsson PG, Lakshmikanth T, Laitinen OH, Utorova R, Jacobson S, Oikarinen M, Domsgen E, Koivunen MR, Chaux P, Devard N, Lecouturier V, Almond J, Knip M, Hyöty H, Flodström-Tullberg M.

Diabetologia. 2015 Feb;58(2):346-54. doi: 10.1007/s00125-014-3436-0. Epub 2014 Nov 5.


Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? Reply to Hansson SF, Korsgren S, Pontén F et al [letter].

Richardson SJ, Leete P, Dhayal S, Russell MA, Oikarinen M, Laiho JE, Svedin E, Lind K, Rosenling T, Chapman N, Bone AJ, Foulis AK, Frisk G, Flodström-Tullberg M, Hober D, Hyoty H, Pugliese A, Morgan NG.

Diabetologia. 2014 Mar;57(3):647-9. doi: 10.1007/s00125-014-3167-2. Epub 2014 Jan 16. No abstract available.


Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein, VP1, in human pancreas.

Richardson SJ, Leete P, Dhayal S, Russell MA, Oikarinen M, Laiho JE, Svedin E, Lind K, Rosenling T, Chapman N, Bone AJ; nPOD-V Consortium, Foulis AK, Frisk G, Flodstrom-Tullberg M, Hober D, Hyoty H, Morgan NG.

Diabetologia. 2014 Feb;57(2):392-401. doi: 10.1007/s00125-013-3094-7. Epub 2013 Nov 5.


Seroconversion to islet autoantibodies after enterovirus infection in early pregnancy.

Rešić Lindehammer S, Honkanen H, Nix WA, Oikarinen M, Lynch KF, Jönsson I, Marsal K, Oberste S, Hyöty H, Lernmark Å.

Viral Immunol. 2012 Aug;25(4):254-61. doi: 10.1089/vim.2012.0022. Epub 2012 Jul 2.


Type 1 diabetes is associated with enterovirus infection in gut mucosa.

Oikarinen M, Tauriainen S, Oikarinen S, Honkanen T, Collin P, Rantala I, Mäki M, Kaukinen K, Hyöty H.

Diabetes. 2012 Mar;61(3):687-91. doi: 10.2337/db11-1157. Epub 2012 Feb 7.


Enteroviruses in the pathogenesis of type 1 diabetes.

Tauriainen S, Oikarinen S, Oikarinen M, Hyöty H.

Semin Immunopathol. 2011 Jan;33(1):45-55. doi: 10.1007/s00281-010-0207-y. Epub 2010 Apr 28. Review.


Evaluation of immunohistochemistry and in situ hybridization methods for the detection of enteroviruses using infected cell culture samples.

Oikarinen M, Tauriainen S, Penttilä P, Keim J, Rantala I, Honkanen T, Hyöty H.

J Clin Virol. 2010 Mar;47(3):224-8. doi: 10.1016/j.jcv.2009.12.020. Epub 2010 Jan 25.


Expression of toll-like receptors in the pancreas of recent-onset fulminant type 1 diabetes.

Shibasaki S, Imagawa A, Tauriainen S, Iino M, Oikarinen M, Abiru H, Tamaki K, Seino H, Nishi K, Takase I, Okada Y, Uno S, Murase-Mishiba Y, Terasaki J, Makino H, Shimomura I, Hyöty H, Hanafusa T.

Endocr J. 2010;57(3):211-9. Epub 2009 Dec 12.


Analysis of pancreas tissue in a child positive for islet cell antibodies.

Oikarinen M, Tauriainen S, Honkanen T, Vuori K, Karhunen P, Vasama-Nolvi C, Oikarinen S, Verbeke C, Blair GE, Rantala I, Ilonen J, Simell O, Knip M, Hyöty H.

Diabetologia. 2008 Oct;51(10):1796-802. doi: 10.1007/s00125-008-1107-8. Epub 2008 Aug 12.


Detection of enteroviruses in the intestine of type 1 diabetic patients.

Oikarinen M, Tauriainen S, Honkanen T, Oikarinen S, Vuori K, Kaukinen K, Rantala I, Mäki M, Hyöty H.

Clin Exp Immunol. 2008 Jan;151(1):71-5. Epub 2007 Nov 7.


Amplifying control RNA for RT-PCR applications by nucleic acid sequence based amplification (NASBA).

Tauriainen S, Dadu E, Oikarinen M, Oikarinen S, Hyöty H.

J Virol Methods. 2006 Mar;132(1-2):222-6. Epub 2005 Nov 28.


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