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Androgens Increase Accumulation of Advanced Glycation End Products in Granulosa Cells by Activating ER Stress in PCOS.

Azhary JMK, Harada M, Kunitomi C, Kusamoto A, Takahashi N, Nose E, Oi N, Wada-Hiraike O, Urata Y, Hirata T, Hirota Y, Koga K, Fujii T, Osuga Y.

Endocrinology. 2020 Feb 1;161(2). pii: bqaa015. doi: 10.1210/endocr/bqaa015.


Preclinical validation of the new vitrification device possessing a feature of absorbing excess vitrification solution for the cryopreservation of human embryos.

Takahashi N, Harada M, Oi N, Izumi G, Momozawa K, Matsuzawa A, Tokunaga Y, Hirata T, Fujii T, Osuga Y.

J Obstet Gynaecol Res. 2020 Feb;46(2):302-309. doi: 10.1111/jog.14176. Epub 2020 Jan 10.


Activation of endoplasmic reticulum stress mediates oxidative stress-induced apoptosis of granulosa cells in ovaries affected by endometrioma.

Kunitomi C, Harada M, Takahashi N, Azhary JMK, Kusamoto A, Nose E, Oi N, Takeuchi A, Wada-Hiraike O, Hirata T, Hirota Y, Koga K, Fujii T, Osuga Y.

Mol Hum Reprod. 2020 Jan 1;26(1):40-52. doi: 10.1093/molehr/gaz066.


3,3'-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX1/2 and ERK1/2.

Tian X, Liu K, Zu X, Ma F, Li Z, Lee M, Chen H, Li Y, Zhao Y, Liu F, Oi N, Bode AM, Dong Z, Kim DJ.

Cancer Lett. 2019 Apr 28;448:20-30. doi: 10.1016/j.canlet.2019.01.031. Epub 2019 Feb 1.


Vertical-type two-dimensional hole gas diamond metal oxide semiconductor field-effect transistors.

Oi N, Inaba M, Okubo S, Tsuyuzaki I, Kageura T, Onoda S, Hiraiwa A, Kawarada H.

Sci Rep. 2018 Jul 13;8(1):10660. doi: 10.1038/s41598-018-28837-5.


Factors associated with successful pregnancy in women of late reproductive age with uterine fibroids who undergo embryo cryopreservation before surgery.

Takahashi N, Harada M, Tanabe R, Takayanagi A, Izumi G, Oi N, Hirata T, Wada-Hiraike O, Fujii T, Osuga Y.

J Obstet Gynaecol Res. 2018 Oct;44(10):1956-1962. doi: 10.1111/jog.13754. Epub 2018 Jul 13.


Role of Carboxyl and Amine Termination on a Boron-Doped Diamond Solution Gate Field Effect Transistor (SGFET) for pH Sensing.

Falina S, Kawai S, Oi N, Yamano H, Kageura T, Suaebah E, Inaba M, Shintani Y, Syamsul M, Kawarada H.

Sensors (Basel). 2018 Jul 6;18(7). pii: E2178. doi: 10.3390/s18072178.


The Ashitaba (Angelica keiskei) Chalcones 4-hydroxyderricin and Xanthoangelol Suppress Melanomagenesis By Targeting BRAF and PI3K.

Zhang T, Wang Q, Fredimoses M, Gao G, Wang K, Chen H, Wang T, Oi N, Zykova TA, Reddy K, Yao K, Ma W, Chang X, Lee MH, Rathore MG, Bode AM, Ashida H, Lippman SM, Dong Z.

Cancer Prev Res (Phila). 2018 Oct;11(10):607-620. doi: 10.1158/1940-6207.CAPR-18-0092. Epub 2018 Jul 6.


LTA4H regulates cell cycle and skin carcinogenesis.

Oi N, Yamamoto H, Langfald A, Bai R, Lee MH, Bode AM, Dong Z.

Carcinogenesis. 2017 Jul 1;38(7):728-737. doi: 10.1093/carcin/bgx049.


TRAF1 Is Critical for DMBA/Solar UVR-Induced Skin Carcinogenesis.

Yamamoto H, Ryu J, Min E, Oi N, Bai R, Zykova TA, Yu DH, Moriyama K, Bode AM, Dong Z.

J Invest Dermatol. 2017 Jun;137(6):1322-1332. doi: 10.1016/j.jid.2016.12.026. Epub 2017 Jan 25.


PPMP, a novel tubulin-depolymerizing agent against esophageal cancer in patient-derived tumor xenografts.

Sheng Y, Liu K, Wu Q, Oi N, Chen H, Reddy K, Jiang Y, Yao K, Li H, Li W, Zhang Y, Saleem M, Ma WY, Bode AM, Dong Z, Dong Z.

Oncotarget. 2016 May 24;7(21):30977-89. doi: 10.18632/oncotarget.9050.


[Quality of Life Is Associated with Combined Lenalidomide and Dexamethasone Treatment in Japanese Patients with Relapsed or Refractory Multiple Myeloma].

Sato H, Nakamura Y, Oi N, Namba K, Taniguchi Y, Yahata H, Komori H, Kobayashi H.

Gan To Kagaku Ryoho. 2015 Dec;42(13):2461-6. Japanese.


Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity.

Kim DJ, Roh E, Lee MH, Oi N, Lim DY, Kim MO, Cho YY, Pugliese A, Shim JH, Chen H, Cho EJ, Kim JE, Kang SC, Paul S, Kang HE, Jung JW, Lee SY, Kim SH, Reddy K, Yeom YI, Bode AM, Dong Z.

Cancer Res. 2016 Mar 1;76(5):1146-1157. doi: 10.1158/0008-5472.CAN-15-0442. Epub 2015 Dec 16.


Glucose Uptake Is Decreased in Affected Lower Leg Muscles of Hemiparetic Persons during Level Walking.

Oi N, Itoh M, Tobimatsu Y, Konno S, Kikuchi S, Iwaya T.

Tohoku J Exp Med. 2015 Dec;237(4):307-15. doi: 10.1620/tjem.237.307.


Development of Novel PET Probes for Central 2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic Acid Receptors.

Oi N, Tokunaga M, Suzuki M, Nagai Y, Nakatani Y, Yamamoto N, Maeda J, Minamimoto T, Zhang MR, Suhara T, Higuchi M.

J Med Chem. 2015 Nov 12;58(21):8444-62. doi: 10.1021/acs.jmedchem.5b00712. Epub 2015 Nov 2.


Aspirin Prevents Colorectal Cancer by Normalizing EGFR Expression.

Li H, Zhu F, Boardman LA, Wang L, Oi N, Liu K, Li X, Fu Y, Limburg PJ, Bode AM, Dong Z.

EBioMedicine. 2015 May 1;2(5):447-455.


Circulating Prostaglandin Biosynthesis in Colorectal Cancer and Potential Clinical Significance.

Li H, Liu K, Boardman LA, Zhao Y, Wang L, Sheng Y, Oi N, Limburg PJ, Bode AM, Dong Z.

EBioMedicine. 2015 Feb 1;2(2):165-171.


3,6,2',4',5'-Pentahydroxyflavone, an orally bioavailable multiple protein kinase inhibitor, overcomes gefitinib resistance in non-small cell lung cancer.

Sheng Y, Li W, Zhu F, Liu K, Chen H, Yao K, Reddy K, Lim DY, Oi N, Li H, Peng C, Ma WY, Bode AM, Dong Z, Dong Z.

J Biol Chem. 2014 Oct 10;289(41):28192-201. doi: 10.1074/jbc.M114.593475. Epub 2014 Aug 13.


Resveratrol induces apoptosis by directly targeting Ras-GTPase-activating protein SH3 domain-binding protein 1.

Oi N, Yuan J, Malakhova M, Luo K, Li Y, Ryu J, Zhang L, Bode AM, Xu Z, Li Y, Lou Z, Dong Z.

Oncogene. 2015 May 14;34(20):2660-71. doi: 10.1038/onc.2014.194. Epub 2014 Jul 7.


[6]-shogaol inhibits growth and induces apoptosis of non-small cell lung cancer cells by directly regulating Akt1/2.

Kim MO, Lee MH, Oi N, Kim SH, Bae KB, Huang Z, Kim DJ, Reddy K, Lee SY, Park SJ, Kim JY, Xie H, Kundu JK, Ryoo ZY, Bode AM, Surh YJ, Dong Z.

Carcinogenesis. 2014 Mar;35(3):683-91. doi: 10.1093/carcin/bgt365. Epub 2013 Nov 26. Erratum in: Carcinogenesis. 2014 May;35(5):1193.


6-C-(E-phenylethenyl)-naringenin suppresses colorectal cancer growth by inhibiting cyclooxygenase-1.

Li H, Zhu F, Chen H, Cheng KW, Zykova T, Oi N, Lubet RA, Bode AM, Wang M, Dong Z.

Cancer Res. 2014 Jan 1;74(1):243-52. doi: 10.1158/0008-5472.CAN-13-2245. Epub 2013 Nov 12.


Select dietary phytochemicals function as inhibitors of COX-1 but not COX-2.

Li H, Zhu F, Sun Y, Li B, Oi N, Chen H, Lubet RA, Bode AM, Dong Z.

PLoS One. 2013 Oct 3;8(10):e76452. doi: 10.1371/journal.pone.0076452. eCollection 2013.


The relationship between psychosocial problems including depression and behavioural trends among middle-aged menopausal women in a cohort study.

Oi N, Ohi K.

Int J Cosmet Sci. 2013 Dec;35(6):581-7. doi: 10.1111/ics.12081. Epub 2013 Aug 21.


A chrysin derivative suppresses skin cancer growth by inhibiting cyclin-dependent kinases.

Liu H, Liu K, Huang Z, Park CM, Thimmegowda NR, Jang JH, Ryoo IJ, He L, Kim SO, Oi N, Lee KW, Soung NK, Bode AM, Yang Y, Zhou X, Erikson RL, Ahn JS, Hwang J, Kim KE, Dong Z, Kim BY.

J Biol Chem. 2013 Sep 6;288(36):25924-37. doi: 10.1074/jbc.M113.464669. Epub 2013 Jul 25.


Synthesis and evaluation of novel radioligands for positron emission tomography imaging of the orexin-2 receptor.

Oi N, Suzuki M, Terauchi T, Tokunaga M, Nakatani Y, Yamamoto N, Fukumura T, Zhang MR, Suhara T, Higuchi M.

J Med Chem. 2013 Aug 22;56(16):6371-85. doi: 10.1021/jm400772t. Epub 2013 Aug 8.


Comparison of the symptoms of menopause and symptoms of thyroid disease in Japanese women aged 35-59 years.

Oi N, Ohi K.

Climacteric. 2013 Oct;16(5):555-60. doi: 10.3109/13697137.2012.717995. Epub 2012 Oct 1.


The psychosocial influence to habit using make-up of women aged 40 to 59 years menopausal Japanese women.

Oi N, Ohi K.

Int J Cosmet Sci. 2013 Feb;35(1):64-8. doi: 10.1111/ics.12005. Epub 2012 Oct 8.


Ceftriaxone, an FDA-approved cephalosporin antibiotic, suppresses lung cancer growth by targeting Aurora B.

Li X, Li H, Li S, Zhu F, Kim DJ, Xie H, Li Y, Nadas J, Oi N, Zykova TA, Yu DH, Lee MH, Kim MO, Wang L, Ma W, Lubet RA, Bode AM, Dong Z, Dong Z.

Carcinogenesis. 2012 Dec;33(12):2548-57. doi: 10.1093/carcin/bgs283. Epub 2012 Sep 7.


Increased risk of placenta previa is associated with endometriosis and tubal factor infertility in assisted reproductive technology pregnancy.

Takemura Y, Osuga Y, Fujimoto A, Oi N, Tsutsumi R, Koizumi M, Yano T, Taketani Y.

Gynecol Endocrinol. 2013 Feb;29(2):113-5. doi: 10.3109/09513590.2012.706669. Epub 2012 Jul 26.


Taxifolin suppresses UV-induced skin carcinogenesis by targeting EGFR and PI3K.

Oi N, Chen H, Ok Kim M, Lubet RA, Bode AM, Dong Z.

Cancer Prev Res (Phila). 2012 Sep;5(9):1103-14. doi: 10.1158/1940-6207.CAPR-11-0397. Epub 2012 Jul 17.


Prediction of molecular targets of cancer preventing flavonoid compounds using computational methods.

Chen H, Yao K, Nadas J, Bode AM, Malakhova M, Oi N, Li H, Lubet RA, Dong Z.

PLoS One. 2012;7(5):e38261. doi: 10.1371/journal.pone.0038261. Epub 2012 May 31.


A study of menopausal symptoms in relation to habits of smoking and make-up using in Japanese women aged 35-59.

Oi N, Ohi K.

Int J Cosmet Sci. 2012 Aug;34(4):332-7. doi: 10.1111/j.1468-2494.2012.00722.x. Epub 2012 May 19.


Norathyriol suppresses skin cancers induced by solar ultraviolet radiation by targeting ERK kinases.

Li J, Malakhova M, Mottamal M, Reddy K, Kurinov I, Carper A, Langfald A, Oi N, Kim MO, Zhu F, Sosa CP, Zhou K, Bode AM, Dong Z.

Cancer Res. 2012 Jan 1;72(1):260-70. doi: 10.1158/0008-5472.CAN-11-2596. Epub 2011 Nov 14.


Embryonic stem-cell-preconditioned microenvironment induces loss of cancer cell properties in human melanoma cells.

Kim MO, Kim SH, Oi N, Lee MH, Yu DH, Kim DJ, Cho EJ, Bode AM, Cho YY, Bowden TG, Dong Z.

Pigment Cell Melanoma Res. 2011 Oct;24(5):922-31. doi: 10.1111/j.1755-148X.2011.00891.x. Epub 2011 Aug 16.


Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene A₄hydrolase.

Oi N, Jeong CH, Nadas J, Cho YY, Pugliese A, Bode AM, Dong Z.

Cancer Res. 2010 Dec 1;70(23):9755-64. doi: 10.1158/0008-5472.CAN-10-2858. Epub 2010 Oct 15.


Absorption of dietary licorice isoflavan glabridin to blood circulation in rats.

Ito C, Oi N, Hashimoto T, Nakabayashi H, Aoki F, Tominaga Y, Yokota S, Hosoe K, Kanazawa K.

J Nutr Sci Vitaminol (Tokyo). 2007 Aug;53(4):358-65.


Yellow tea is more potent than other types of tea in suppressing liver toxicity induced by carbon tetrachloride in rats.

Hashimoto T, Goto M, Sakakibara H, Oi N, Okamoto M, Kanazawa K.

Phytother Res. 2007 Jul;21(7):668-70.


Variation of neck muscle strength along the human cervical spine.

Oi N, Pandy MG, Myers BS, Nightingale RW, Chancey VC.

Stapp Car Crash J. 2004 Nov;48:397-417.


Effects of combined administration of quercetin, rutin, and extract of white radish sprout rich in kaempferol glycosides on the metabolism in rats.

Hashimoto T, Ueda Y, Oi N, Sakakibara H, Piao C, Ashida H, Goto M, Kanazawa K.

Biosci Biotechnol Biochem. 2006 Jan;70(1):279-81.


The difference among generations in evaluating interior lighting environment.

Oi N.

J Physiol Anthropol Appl Human Sci. 2005 Jan;24(1):87-91.


Reliability and validity of classification of senile postural deformity in mass examinations.

Oi N, Tobimatsu Y, Iwaya T, Okada Y, Gushiken S, Kusano S, Yamamoto M, Takakura Y, Suyama T.

Tohoku J Exp Med. 2004 Feb;202(2):105-12.


FDG-PET imaging of lower extremity muscular activity during level walking.

Oi N, Iwaya T, Itoh M, Yamaguchi K, Tobimatsu Y, Fujimoto T.

J Orthop Sci. 2003;8(1):55-61.


Enantiomer separation with poly-(R)-1- (alpha-naphthyl)-ethyl-methacrylamide coated on ODS silica gel by reversed phase HPLC.

Oi N, Hashimoto S, Ishizuka N, Ohtake J.

Biomed Chromatogr. 1997 Sep-Oct;11(5):296-7. No abstract available.


Enantiomer separation by gas and high-performance liquid chromatography with tripeptide derivatives as chiral stationary phases.

Oi N, Kitahara H, Matsushita Y, Kisu N.

J Chromatogr A. 1996 Jan 26;722(1-2):229-32.


[A case of progressive spinal muscular atrophy with disorder of intestinal motility improved by administration of erythromycin].

Ii T, Oi N, Shioya K, Kawano T, Nakahara S, Matsukura S.

Nihon Naika Gakkai Zasshi. 1992 Aug 10;81(8):1261-2. Japanese. No abstract available.


Improved procedure for determination of indomethacin in plasma by capillary gas chromatography after solid-phase extraction.

Nishioka R, Harimoto T, Umeda I, Yamamoto S, Oi N.

J Chromatogr. 1990 Mar 16;526(1):210-4. No abstract available.


Direct separation of alpha-hydroxycarboxylic acid ester enantiomers by gas chromatography with optically active copper(II) complexes.

Oi N, Horiba M, Kitahara H, Doi T, Tani T, Sakakibara T.

J Chromatogr. 1980 Dec 19;202(2):305-8. No abstract available.


Gas chromatographic separation of enantiomers of some dipeptides on an optically active stationary phase.

Oi N, Horiba M, Kitahara H, Shimada H.

J Chromatogr. 1980 Dec 19;202(2):302-4. No abstract available.


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