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Items: 1 to 50 of 665

1.

Ovomucoid-specific IgG4 level in cord blood associates negatively with later sensitization.

Irahara M, Shinahara W, Mayumi S, Ogawa Y, Shitsukawa K, Kenji K, Ohya Y, Saito H, Kagami S, Hiroshi K.

Pediatr Allergy Immunol. 2019 Aug 23. doi: 10.1111/pai.13116. [Epub ahead of print]

PMID:
31441111
2.

Psychometric profiles of the Ages and Stages Questionnaires, Japanese translation.

Mezawa H, Aoki S, Nakayama SF, Nitta H, Ikeda N, Kato K, Tamai S, Takekoh M, Sanefuji M, Ohga S, Oda M, Mitsubuchi H, Senju A, Kusuhara K, Kuwajima M, Koeda T, Ohya Y, Hashimoto K.

Pediatr Int. 2019 Aug 16. doi: 10.1111/ped.13990. [Epub ahead of print]

PMID:
31419360
3.

The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019).

Umemura S, Arima H, Arima S, Asayama K, Dohi Y, Hirooka Y, Horio T, Hoshide S, Ikeda S, Ishimitsu T, Ito M, Ito S, Iwashima Y, Kai H, Kamide K, Kanno Y, Kashihara N, Kawano Y, Kikuchi T, Kitamura K, Kitazono T, Kohara K, Kudo M, Kumagai H, Matsumura K, Matsuura H, Miura K, Mukoyama M, Nakamura S, Ohkubo T, Ohya Y, Okura T, Rakugi H, Saitoh S, Shibata H, Shimosawa T, Suzuki H, Takahashi S, Tamura K, Tomiyama H, Tsuchihashi T, Ueda S, Uehara Y, Urata H, Hirawa N.

Hypertens Res. 2019 Sep;42(9):1235-1481. doi: 10.1038/s41440-019-0284-9. Review. No abstract available.

PMID:
31375757
4.

[A case of autoimmune hemolytic anemia diagnosed by occurrence of cardioembolic stroke].

Kimura S, Osaki M, Sakai S, Ohya Y, Ago T, Kitazono T, Arakawa S.

Nihon Ronen Igakkai Zasshi. 2019;56(3):331-335. doi: 10.3143/geriatrics.56.331. Japanese.

5.

Effect of Standard vs Intensive Blood Pressure Control on the Risk of Recurrent Stroke: A Randomized Clinical Trial and Meta-analysis.

Kitagawa K, Yamamoto Y, Arima H, Maeda T, Sunami N, Kanzawa T, Eguchi K, Kamiyama K, Minematsu K, Ueda S, Rakugi H, Ohya Y, Kohro T, Yonemoto K, Okada Y, Higaki J, Tanahashi N, Kimura G, Umemura S, Matsumoto M, Shimamoto K, Ito S, Saruta T, Shimada K; Recurrent Stroke Prevention Clinical Outcome (RESPECT) Study Group.

JAMA Neurol. 2019 Jul 29. doi: 10.1001/jamaneurol.2019.2167. [Epub ahead of print]

PMID:
31355878
6.

Cucurbitacin B Exerts Antiaging Effects in Yeast by Regulating Autophagy and Oxidative Stress.

Lin Y, Kotakeyama Y, Li J, Pan Y, Matsuura A, Ohya Y, Yoshida M, Xiang L, Qi J.

Oxid Med Cell Longev. 2019 Jun 2;2019:4517091. doi: 10.1155/2019/4517091. eCollection 2019.

7.

Effect of filaggrin loss-of-function mutations on atopic dermatitis in young age: a longitudinal birth cohort study.

Koseki R, Morii W, Noguchi E, Ishikawa M, Yang L, Yamamoto-Hanada K, Narita M, Saito H, Ohya Y.

J Hum Genet. 2019 Sep;64(9):911-917. doi: 10.1038/s10038-019-0628-y. Epub 2019 Jun 28.

PMID:
31249362
8.

Comparison of blood pressure values-self-measured at home, measured at an unattended office, and measured at a conventional attended office.

Asayama K, Ohkubo T, Rakugi H, Miyakawa M, Mori H, Katsuya T, Ikehara Y, Ueda S, Ohya Y, Tsuchihashi T, Kario K, Miura K, Hasebe N, Ito S, Umemura S; Japanese Society of Hypertension Working Group on the COmparison of Self-measured home, Automated unattended office and Conventional attended office blood pressure (COSAC) study.

Hypertens Res. 2019 Jun 21. doi: 10.1038/s41440-019-0287-6. [Epub ahead of print]

PMID:
31222188
9.

Hypogenesis of right hepatic lobe in a laparoscopic cholecystectomy for acute gallstone cholecystitis: A case report.

Fujimoto Y, Ohya Y, Irie T, Kumamoto S, Tuji A, Nakamura S, Shibata H, Kuramoto K, Hayashi H, Araki Y, Iizaka M, Tomiyasu S, Inomata Y.

Intractable Rare Dis Res. 2019 May;8(2):146-149. doi: 10.5582/irdr.2019.01053.

10.

Efficacy of repeated balloon venoplasty for treatment of hepatic venous outflow obstruction after pediatric living-donor liver transplantation: A single-institution experience.

Shimata K, Sugawara Y, Honda M, Ikeda O, Tamura Y, Hayashida S, Ohya Y, Yamamoto H, Yamashita Y, Inomata Y, Hibi T.

Pediatr Transplant. 2019 Sep;23(6):e13522. doi: 10.1111/petr.13522. Epub 2019 Jun 18.

PMID:
31210388
11.

Genome editing to generate nonfoam-forming sake yeast strains.

Ohnuki S, Kashima M, Yamada T, Ghanegolmohammadi F, Zhou Y, Goshima T, Maruyama JI, Kitamoto K, Hirata D, Akao T, Ohya Y.

Biosci Biotechnol Biochem. 2019 Aug;83(8):1583-1593. doi: 10.1080/09168451.2019.1631146. Epub 2019 Jun 12.

PMID:
31189439
12.

Ana o 3-specific IgE is a predictive marker for cashew oral food challenge failure.

Sato S, Movérare R, Ohya Y, Ito K, Nagao M, Borres MP, Ebisawa M.

J Allergy Clin Immunol Pract. 2019 May 17. pii: S2213-2198(19)30460-X. doi: 10.1016/j.jaip.2019.04.049. [Epub ahead of print] No abstract available.

PMID:
31108216
13.

Artificial Smooth Muscle Model Composed of Hierarchically Ordered Microtubule Asters Mediated by DNA Origami Nanostructures.

Matsuda K, Kabir AMR, Akamatsu N, Saito A, Ishikawa S, Matsuyama T, Ditzer O, Islam MS, Ohya Y, Sada K, Konagaya A, Kuzuya A, Kakugo A.

Nano Lett. 2019 Jun 12;19(6):3933-3938. doi: 10.1021/acs.nanolett.9b01201. Epub 2019 May 3.

PMID:
31037942
14.

JSH Statement: Asahikawa declaration in promotion of diversity by the Japanese society of hypertension-the JSH Asahikawa declaration.

Nakamura S, Hasebe N, Yatabe M, Kishi T, Ishida M, Ichihara A, Node K, Ishimitsu T, Itoh H, Ito M, Ohishi M, Ohkubo T, Kai H, Kashihara N, Kario K, Saitoh S, Tsuchihashi T, Nishiyama A, Higaki J, Miura K, Rakugi H, Kawano Y, Tamura K, Yatabe T, Ohya Y, Ito S.

Hypertens Res. 2019 Apr 8. doi: 10.1038/s41440-019-0261-3. [Epub ahead of print] No abstract available.

PMID:
30962519
15.

Four phenotypes of atopic dermatitis in Japanese children: A general population birth cohort study.

Yamamoto-Hanada K, Yang L, Saito-Abe M, Sato M, Inuzuka Y, Toyokuni K, Nishimura K, Irahara M, Ishikawa F, Miyaji Y, Fukuie T, Narita M, Saito H, Ohya Y.

Allergol Int. 2019 Mar 30. pii: S1323-8930(19)30032-2. doi: 10.1016/j.alit.2019.02.010. [Epub ahead of print] No abstract available.

16.

Target of Triglycerides as Residual Risk for Cardiovascular Events in Patients With Coronary Artery Disease - Post Hoc Analysis of the FMD-J Study A.

Kajikawa M, Maruhashi T, Kishimoto S, Matsui S, Hashimoto H, Takaeko Y, Yusoff FM, Kihara Y, Chayama K, Goto C, Noma K, Nakashima A, Tomiyama H, Takase B, Kohro T, Suzuki T, Ishizu T, Ueda S, Yamazaki T, Furumoto T, Kario K, Inoue T, Koba S, Watanabe K, Takemoto Y, Hano T, Sata M, Ishibashi Y, Node K, Maemura K, Ohya Y, Furukawa T, Ito H, Ikeda H, Yamashina A, Higashi Y.

Circ J. 2019 Apr 25;83(5):1064-1071. doi: 10.1253/circj.CJ-18-1082. Epub 2019 Mar 26.

17.

Topical corticosteroid phobia among caretakers of children with atopic dermatitis: A cross-sectional study using TOPICOP in Japan.

Saito-Abe M, Futamura M, Yamamoto-Hanada K, Yang L, Suzuki K, Ohya Y.

Pediatr Dermatol. 2019 May;36(3):311-316. doi: 10.1111/pde.13784. Epub 2019 Mar 18.

PMID:
30882946
18.

Trajectories of class-switching-related egg and cow's milk allergen-specific immunoglobulin isotype formation and its modification by eczema with low- and high-affinity immunoglobulin E during early infancy.

Irahara M, Shinahara W, Sugimoto M, Ogawa Y, Shitsukawa K, Kubota K, Yang L, Ohya Y, Saito H, Kagami S, Arisawa K, Kido H.

Immun Inflamm Dis. 2019 Jun;7(2):74-85. doi: 10.1002/iid3.245. Epub 2019 Mar 11.

19.

Low-dose l-isoproterenol versus salbutamol in hospitalized pediatric patients with severe acute exacerbation of asthma: A double-blind, randomized controlled trial.

Katsunuma T, Fujisawa T, Maekawa T, Akashi K, Ohya Y, Adachi Y, Hashimoto K, Mizuno M, Imai T, Oba MS, Sako M, Ohashi Y, Nakamura H.

Allergol Int. 2019 Jul;68(3):335-341. doi: 10.1016/j.alit.2019.02.001. Epub 2019 Mar 5.

20.

Egg antigen was more abundant than mite antigen in children's bedding: Findings of the pilot study of the Japan Environment and Children's Study (JECS).

Kitazawa H, Yamamoto-Hanada K, Saito-Abe M, Ayabe T, Mezawa H, Ishitsuka K, Konishi M, Nakayama SF, Michikawa T, Senju A, Tsuji M, Kusuhara K, Sanefuji M, Ohga S, Oda M, Mitsubuchi H, Katoh T, Ikegami A, Mise N, Matsumoto K, Saito H, Ohya Y.

Allergol Int. 2019 Jul;68(3):391-393. doi: 10.1016/j.alit.2019.02.005. Epub 2019 Mar 5. No abstract available.

21.

Febuxostat for Cerebral and CaRdiorenovascular Events PrEvEntion StuDy.

Kojima S, Matsui K, Hiramitsu S, Hisatome I, Waki M, Uchiyama K, Yokota N, Tokutake E, Wakasa Y, Jinnouchi H, Kakuda H, Hayashi T, Kawai N, Mori H, Sugawara M, Ohya Y, Kimura K, Saito Y, Ogawa H.

Eur Heart J. 2019 Jun 7;40(22):1778-1786. doi: 10.1093/eurheartj/ehz119.

22.

Complications and adverse outcomes in pregnancy and childbirth among women who conceived by assisted reproductive technologies: a nationwide birth cohort study of Japan environment and children's study.

Nagata C, Yang L, Yamamoto-Hanada K, Mezawa H, Ayabe T, Ishizuka K, Konishi M, Ohya Y, Saito H, Sago H; Japan Environment & Children’s Study Group.

BMC Pregnancy Childbirth. 2019 Feb 20;19(1):77. doi: 10.1186/s12884-019-2213-y.

23.

Exposure to paraben and triclosan and allergic diseases in Tokyo: A pilot cross-sectional study.

Mitsui-Iwama M, Yamamoto-Hanada K, Fukutomi Y, Hirota R, Muto G, Nakamura T, Yoshikawa T, Nakamura H, Mikami M, Morioka I, Ohya Y.

Asia Pac Allergy. 2019 Jan 21;9(1):e5. doi: 10.5415/apallergy.2019.9.e5. eCollection 2019 Jan.

24.

Association between high-normal ankle-brachial index and hypertension incidence: the Okinawa Peripheral Arterial Disease Study.

Ishida A, Kinjo K, Maeda T, Ohya Y.

J Hypertens. 2019 May;37(5):935-941. doi: 10.1097/HJH.0000000000001995.

PMID:
30640883
25.

History, lineage and phenotypic differentiation of sake yeast.

Ohya Y, Kashima M.

Biosci Biotechnol Biochem. 2019 Aug;83(8):1442-1448. doi: 10.1080/09168451.2018.1564620. Epub 2019 Jan 9.

PMID:
30626273
26.

JSH Statement: Kyoto declaration on hypertension research in Asia.

Ito M, Ishimitsu T, Ichihara A, Itoh H, Ohishi M, Ohkubo T, Kai H, Kashihara N, Kario K, Saitoh S, Tsuchihashi T, Nakamura S, Nishiyama A, Node K, Hasebe N, Higaki J, Miura K, Rakugi H, Tamura K, Kawano Y, Yatabe T, Ohya Y, Ito S.

Hypertens Res. 2019 Jun;42(6):759-760. doi: 10.1038/s41440-018-0172-8. Epub 2019 Jan 7. No abstract available.

PMID:
30617311
27.

Importance of avoiding surgery delays after initial discovery of suspected non-small-cell lung cancer in clinical stage IA patients.

Kuroda H, Sugita Y, Ohya Y, Yoshida T, Arimura T, Sakakura N, Hida T, Yatabe Y, Sakao Y.

Cancer Manag Res. 2018 Dec 20;11:107-115. doi: 10.2147/CMAR.S180757. eCollection 2019.

28.

Early aggressive intervention for infantile atopic dermatitis to prevent development of food allergy: a multicenter, investigator-blinded, randomized, parallel group controlled trial (PACI Study)-protocol for a randomized controlled trial.

Yamamoto-Hanada K, Kobayashi T, Williams HC, Mikami M, Saito-Abe M, Morita K, Natsume O, Sato M, Iwama M, Miyaji Y, Miyata M, Inagaki S, Tatsuki F, Masami N, Nakayama SF, Kido H, Saito H, Ohya Y.

Clin Transl Allergy. 2018 Nov 23;8:47. doi: 10.1186/s13601-018-0233-8. eCollection 2018.

29.

Risky Health Behaviors of Teenage Mothers and Infant Outcomes in the Japan Environment and Children's Study: A Nationwide Cohort Study.

Ishitsuka K, Yamamoto-Hanada K, Ayabe T, Mezawa H, Konishi M, Saito-Abe M, Ohya Y; Japan Environment and Children's Study Group.

J Pediatr Adolesc Gynecol. 2019 Apr;32(2):146-152. doi: 10.1016/j.jpag.2018.10.009. Epub 2018 Nov 3.

PMID:
30395983
30.

Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions.

Simpkins SW, Nelson J, Deshpande R, Li SC, Piotrowski JS, Wilson EH, Gebre AA, Safizadeh H, Okamoto R, Yoshimura M, Costanzo M, Yashiroda Y, Ohya Y, Osada H, Yoshida M, Boone C, Myers CL.

PLoS Comput Biol. 2018 Oct 30;14(10):e1006532. doi: 10.1371/journal.pcbi.1006532. eCollection 2018 Oct.

31.

Yeast species-specific, differential inhibition of β-1,3-glucan synthesis by poacic acid and caspofungin.

Lee KK, Kubo K, Abdelaziz JA, Cunningham I, de Silva Dantas A, Chen X, Okada H, Ohya Y, Gow NAR.

Cell Surf. 2018 Sep;3:12-25. doi: 10.1016/j.tcsw.2018.09.001.

32.

Triclosan-induced alteration of gut microbiome and aggravation of asthmatic airway response in aeroallergen-sensitized mice.

Hirota R, Ohya Y, Yamamoto-Hanada K, Fukutomi Y, Muto G, Ngatu NR, Nakamura T, Nakamura H.

Allergy. 2019 May;74(5):996-999. doi: 10.1111/all.13639. Epub 2019 Feb 1. No abstract available.

33.

Simulated microgravity triggers characteristic morphology and stress response in Saccharomyces cerevisiae.

Nemoto S, Ohnuki S, Abe F, Ohya Y.

Yeast. 2019 Feb;36(2):85-97. doi: 10.1002/yea.3361. Epub 2018 Nov 7.

PMID:
30350382
34.

The Japanese Society of Hypertension-Digest of plan for the future.

Node K, Kishi T, Tanaka A, Itoh H, Rakugi H, Ohya Y, Miura K, Okamura T, Ishimitsu T, Ichihara A, Ito M, Ohishi M, Ohkubo T, Kai H, Kashihara N, Kario K, Saitoh S, Tsuchihashi T, Nakamura S, Nishiyama A, Hasebe N, Higaki J, Tamura K, Kawano Y, Yatabe T, Ito S; JSH Future Plan Working Group and Executive Board Members.

Hypertens Res. 2018 Dec;41(12):989-990. doi: 10.1038/s41440-018-0111-8. Epub 2018 Oct 11. No abstract available.

PMID:
30310169
35.

A case of aortic valve laceration after balloon aortic valvuloplasty with morphological features.

Toma Y, Iwabuchi M, Nagata H, Goya K, Shiohira T, Yamazato S, Ikemiyagi H, Ohshiro K, Shinzato T, Ohya Y.

J Cardiol Cases. 2017 Sep 1;16(6):210-212. doi: 10.1016/j.jccase.2017.08.002. eCollection 2017 Dec.

36.

Prevalence of Congenital Anomalies in the Japan Environment and Children's Study.

Mezawa H, Tomotaki A, Yamamoto-Hanada K, Ishitsuka K, Ayabe T, Konishi M, Saito M, Yang L, Suganuma N, Hirahara F, Nakayama SF, Saito H, Ohya Y.

J Epidemiol. 2019 Jul 5;29(7):247-256. doi: 10.2188/jea.JE20180014. Epub 2018 Sep 22.

37.

Association between stroke-like episodes and neuronal hyperexcitability in MELAS with m.3243A>G: A case report.

Sakai S, Osaki M, Hidaka M, Kimura S, Ohya Y, Ago T, Kitazono T, Arakawa S.

eNeurologicalSci. 2018 Aug 22;12:39-41. doi: 10.1016/j.ensci.2018.08.003. eCollection 2018 Sep.

38.

Factors determining parenting stress in mothers of children with atopic dermatitis.

Yamaguchi C, Ebara T, Hosokawa R, Futamura M, Ohya Y, Asano M.

Allergol Int. 2019 Apr;68(2):185-190. doi: 10.1016/j.alit.2018.08.006. Epub 2018 Sep 11.

39.

Self-efficacy of food allergy management in elementary school personnel in Tokyo.

Yamamoto-Hanada K, Ohya Y.

Pediatr Int. 2018 Aug;60(8):769-770. doi: 10.1111/ped.13610. No abstract available.

PMID:
30160033
40.

Intracerebroventricular administration of bone marrow-derived cells attenuates angiotensin II-initiated neurogenic hypertension in rats.

Yamazato M, Ishida A, Yamazato Y, Nakamura T, Ohya Y.

Hypertens Res. 2018 Oct;41(10):828-838. doi: 10.1038/s41440-018-0088-3. Epub 2018 Aug 17.

PMID:
30120396
41.

Implications of maintenance of mother-bud neck size in diverse vital processes of Saccharomyces cerevisiae.

Kubo K, Okada H, Shimamoto T, Kimori Y, Mizunuma M, Bi E, Ohnuki S, Ohya Y.

Curr Genet. 2019 Feb;65(1):253-267. doi: 10.1007/s00294-018-0872-2. Epub 2018 Jul 31.

PMID:
30066140
42.

[ESTIMATED NUMBER OF PATIENTS WITH FOOD ALLERGY IN JAPAN: THE PRESENT STATUS AND ISSUES REGARDING EPIDEMIOLOGICAL INVESTIGATION].

Matsubara Y, Ae R, Ohya Y, Akiyama H, Imai T, Matsumoto K, Fukuie T, Aoyama Y, Makino N, Nakamura Y, Saito H.

Arerugi. 2018;67(6):767-773. doi: 10.15036/arerugi.67.767. Japanese.

PMID:
30022786
43.

Endothelial Dysfunction, Increased Arterial Stiffness, and Cardiovascular Risk Prediction in Patients With Coronary Artery Disease: FMD-J (Flow-Mediated Dilation Japan) Study A.

Maruhashi T, Soga J, Fujimura N, Idei N, Mikami S, Iwamoto Y, Iwamoto A, Kajikawa M, Matsumoto T, Oda N, Kishimoto S, Matsui S, Hashimoto H, Aibara Y, Mohamad Yusoff F, Hidaka T, Kihara Y, Chayama K, Noma K, Nakashima A, Goto C, Tomiyama H, Takase B, Kohro T, Suzuki T, Ishizu T, Ueda S, Yamazaki T, Furumoto T, Kario K, Inoue T, Koba S, Watanabe K, Takemoto Y, Hano T, Sata M, Ishibashi Y, Node K, Maemura K, Ohya Y, Furukawa T, Ito H, Ikeda H, Yamashina A, Higashi Y.

J Am Heart Assoc. 2018 Jul 12;7(14). pii: e008588. doi: 10.1161/JAHA.118.008588.

44.

Urinary PGDM, a prostaglandin D2 metabolite, is a novel biomarker for objectively detecting allergic reactions of food allergy.

Inagaki S, Maeda S, Narita M, Nakamura T, Shimosawa T, Murata T, Ohya Y.

J Allergy Clin Immunol. 2018 Nov;142(5):1634-1636.e10. doi: 10.1016/j.jaci.2018.06.032. Epub 2018 Jul 5. No abstract available.

PMID:
29981807
45.

Hyponatremia and mortality among very elderly residents in a geriatric health service facility.

Naka T, Kohagura K, Kochi M, Ohya Y.

Clin Exp Nephrol. 2018 Dec;22(6):1404-1410. doi: 10.1007/s10157-018-1607-x. Epub 2018 Jun 27.

PMID:
29951722
46.

Cross-sectional and longitudinal associations between serum uric acid and endothelial function in subjects with treated hypertension.

Tanaka A, Kawaguchi A, Tomiyama H, Ishizu T, Matsumoto C, Higashi Y, Takase B, Suzuki T, Ueda S, Yamazaki T, Furumoto T, Kario K, Inoue T, Koba S, Takemoto Y, Hano T, Sata M, Ishibashi Y, Maemura K, Ohya Y, Furukawa T, Ito H, Yamashina A, Node K.

Int J Cardiol. 2018 Dec 1;272:308-313. doi: 10.1016/j.ijcard.2018.06.017. Epub 2018 Jun 6.

PMID:
29895425
47.

The budding yeast RSC complex maintains ploidy by promoting spindle pole body insertion.

Sing TL, Hung MP, Ohnuki S, Suzuki G, San Luis BJ, McClain M, Unruh JR, Yu Z, Ou J, Marshall-Sheppard J, Huh WK, Costanzo M, Boone C, Ohya Y, Jaspersen SL, Brown GW.

J Cell Biol. 2018 Jul 2;217(7):2445-2462. doi: 10.1083/jcb.201709009. Epub 2018 Jun 6.

48.

An independent relation of atopic dermatitis to exercise-induced wheezing in asthmatic children.

Honjo S, Murakami Y, Odajima H, Adachi Y, Yoshida K, Ohya Y, Akasawa A.

Allergol Int. 2019 Jan;68(1):26-32. doi: 10.1016/j.alit.2018.04.013. Epub 2018 May 30.

49.

Genetic dissection of the signaling pathway required for the cell wall integrity checkpoint.

Sukegawa Y, Negishi T, Kikuchi Y, Ishii K, Imanari M, Ghanegolmohammadi F, Nogami S, Ohya Y.

J Cell Sci. 2018 Jul 9;131(13). pii: jcs219063. doi: 10.1242/jcs.219063.

50.

Preparation of Biodegradable Oligo(lactide)s-Grafted Dextran Nanogels for Efficient Drug Delivery by Controlling Intracellular Traffic.

Ohya Y, Takahashi A, Kuzuya A.

Int J Mol Sci. 2018 May 30;19(6). pii: E1606. doi: 10.3390/ijms19061606.

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