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Application of Large Electronic Medical Database for Detecting Undiagnosed Patients in the General Population.

Ishii T, Akaishi T, Fujimori K, Abe M, Ohara M, Shoji M, Takayama S, Sato C, Nakayama M, Tsuji I, Nakano T, Ohuchi N, Kamei T.

Tohoku J Exp Med. 2019 Oct;249(2):113-119. doi: 10.1620/tjem.249.113.


The p21 levels have the potential to be a monitoring marker for ribociclib in breast cancer.

Iida M, Nakamura M, Tokuda E, Toyosawa D, Niwa T, Ohuchi N, Ishida T, Hayashi SI.

Oncotarget. 2019 Aug 6;10(47):4907-4918. doi: 10.18632/oncotarget.27127. eCollection 2019 Aug 6.


Preoperative change of modified Glasgow prognostic score after stenting predicts the long-term outcomes of obstructive colorectal cancer.

Sato R, Oikawa M, Kakita T, Okada T, Abe T, Yazawa T, Tsuchiya H, Akazawa N, Sato M, Ohira T, Harada Y, Okano H, Ito K, Ohuchi N, Tsuchiya T.

Surg Today. 2019 Aug 12. doi: 10.1007/s00595-019-01862-1. [Epub ahead of print]


Automated Quantification of Extranuclear ERα using Phosphor-integrated Dots for Predicting Endocrine Therapy Resistance in HR+/HER2- Breast Cancer.

Guo Z, Tada H, Kitamura N, Hamada Y, Miyashita M, Harada-Shoji N, Sato A, Hamanaka Y, Tsuboi K, Harada N, Takano-Kasuya M, Okada H, Nakano Y, Ohuchi N, Hayashi SI, Ishida T, Gonda K.

Cancers (Basel). 2019 Apr 12;11(4). pii: E526. doi: 10.3390/cancers11040526.


Impact of Topoisomerase IIα, PTEN, ABCC1/MRP1, and KI67 on triple-negative breast cancer patients treated with neoadjuvant chemotherapy.

Guestini F, Ono K, Miyashita M, Ishida T, Ohuchi N, Nakagawa S, Hirakawa H, Tamaki K, Ohi Y, Rai Y, Sagara Y, Sasano H, McNamara KM.

Breast Cancer Res Treat. 2019 Jan;173(2):275-288. doi: 10.1007/s10549-018-4985-6. Epub 2018 Oct 10.


Do you know how to get the J-START quality assurance guideline?

Uematsu T, Nakamura S, Ohuchi N.

Breast Cancer. 2018 Jul;25(4):375-376. doi: 10.1007/s12282-018-0867-3. Epub 2018 May 9. No abstract available.


Newly-Developed Positron Emission Mammography (PEM) Device for the Detection of Small Breast Cancer.

Yanai A, Itoh M, Hirakawa H, Yanai K, Tashiro M, Harada R, Yoshikawa A, Yamamoto S, Ohuchi N, Ishida T.

Tohoku J Exp Med. 2018 May;245(1):13-19. doi: 10.1620/tjem.245.13.


Increased centrosome number in BRCA-related breast cancer specimens determined by immunofluorescence analysis.

Watanabe G, Chiba N, Nomizu T, Furuta A, Sato K, Miyashita M, Tada H, Suzuki A, Ohuchi N, Ishida T.

Cancer Sci. 2018 Jun;109(6):2027-2035. doi: 10.1111/cas.13595. Epub 2018 May 15.


Molecular and clinical features of the TP53 signature gene expression profile in early-stage breast cancer.

Yamaguchi S, Takahashi S, Mogushi K, Izumi Y, Nozaki Y, Nomizu T, Kakugawa Y, Ishida T, Ohuchi N, Ishioka C, Kato S.

Oncotarget. 2018 Feb 8;9(18):14193-14206. doi: 10.18632/oncotarget.24447. eCollection 2018 Mar 6.


Effect of the normal mammary differentiation regulator ELF5 upon clinical outcomes of triple negative breast cancers patients.

Omata F, McNamara KM, Suzuki K, Abe E, Hirakawa H, Ishida T, Ohuchi N, Sasano H.

Breast Cancer. 2018 Jul;25(4):489-496. doi: 10.1007/s12282-018-0842-z. Epub 2018 Feb 2.


Alcohol Consumption and Breast Cancer Risk According to Hormone Receptor Status in Japanese Women: A Case-Control Study.

Takizawa Y, Kawai M, Kakugawa Y, Nishino Y, Ohuchi N, Minami Y.

Tohoku J Exp Med. 2018 Jan;244(1):63-73. doi: 10.1620/tjem.244.63.


18F-fluorodeoxyglucose specimen-positron emission mammography delineates tumour extension in breast-conserving surgery: Preliminary results.

Watanabe G, Itoh M, Duan X, Watabe H, Mori N, Tada H, Suzuki A, Miyashita M, Ohuchi N, Ishida T.

Eur Radiol. 2018 May;28(5):1929-1937. doi: 10.1007/s00330-017-5170-8. Epub 2017 Dec 7.


The Optimization of the Prevascularization Procedures for Improving Subcutaneous Islet Engraftment.

Uematsu SS, Inagaki A, Nakamura Y, Imura T, Igarashi Y, Fathi I, Miyagi S, Ohuchi N, Satomi S, Goto M.

Transplantation. 2018 Mar;102(3):387-395. doi: 10.1097/TP.0000000000001970.


Effects of cytokines derived from cancer-associated fibroblasts on androgen synthetic enzymes in estrogen receptor-negative breast carcinoma.

Kikuchi K, McNamara KM, Miki Y, Moon JY, Choi MH, Omata F, Sakurai M, Onodera Y, Rai Y, Ohi Y, Sagara Y, Miyashita M, Ishida T, Ohuchi N, Sasano H.

Breast Cancer Res Treat. 2017 Dec;166(3):709-723. doi: 10.1007/s10549-017-4464-5. Epub 2017 Aug 22.


Quantitative diagnostic imaging of cancer tissues by using phosphor-integrated dots with ultra-high brightness.

Gonda K, Watanabe M, Tada H, Miyashita M, Takahashi-Aoyama Y, Kamei T, Ishida T, Usami S, Hirakawa H, Kakugawa Y, Hamanaka Y, Yoshida R, Furuta A, Okada H, Goda H, Negishi H, Takanashi K, Takahashi M, Ozaki Y, Yoshihara Y, Nakano Y, Ohuchi N.

Sci Rep. 2017 Aug 8;7(1):7509. doi: 10.1038/s41598-017-06534-z.


The Optimization of Short-Term Hepatocyte Preservation Before Transplantation.

Fukuoka K, Inagaki A, Nakamura Y, Matsumura M, Yoshida S, Imura T, Igarashi Y, Miyagi S, Ohashi K, Enosawa S, Kamei T, Unno M, Ohuchi N, Satomi S, Goto M.

Transplant Direct. 2017 Jun 19;3(7):e176. doi: 10.1097/TXD.0000000000000687. eCollection 2017 Jul.


Oral Steroid Use and Abdominal Aortic Aneurysm Expansion - Positive Association.

Tajima Y, Goto H, Ohara M, Hashimoto M, Akamatsu D, Shimizu T, Miyama N, Tsuchida K, Kawamura K, Umetsu M, Suzuki S, Ohuchi N.

Circ J. 2017 Nov 24;81(12):1774-1782. doi: 10.1253/circj.CJ-16-0902. Epub 2017 Jun 30.


Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment.

Sakurai M, Miki Y, Takagi K, Suzuki T, Ishida T, Ohuchi N, Sasano H.

Breast Cancer Res. 2017 Jun 19;19(1):70. doi: 10.1186/s13058-017-0863-0.


Splenectomy for Severe Intestinal Bleeding Caused by Portal Hypertensive Enteropathy After Pediatric Living-Donor Liver Transplantation: A Report of Three Cases.

Tokodai K, Kawagishi N, Miyagi S, Nakanishi C, Hara Y, Nakanishi W, Kamei T, Ohuchi N.

Transplant Proc. 2017 Jun;49(5):1129-1132. doi: 10.1016/j.transproceed.2017.03.029.


Minimal impact of postmastectomy radiation therapy on locoregional recurrence for breast cancer patients with 1 to 3 positive lymph nodes in the modern treatment era.

Miyashita M, Tada H, Suzuki A, Watanabe G, Hirakawa H, Amari M, Kakugawa Y, Kawai M, Furuta A, Sato K, Yoshida R, Ebata A, Sasano H, Jingu K, Ohuchi N, Ishida T.

Surg Oncol. 2017 Jun;26(2):163-170. doi: 10.1016/j.suronc.2017.03.003. Epub 2017 Mar 16.


Arterial and biliary complications after living donor liver transplantation: a single-center retrospective study and literature review.

Miyagi S, Kakizaki Y, Shimizu K, Miyazawa K, Nakanishi W, Hara Y, Tokodai K, Nakanishi C, Kamei T, Ohuchi N, Satomi S.

Surg Today. 2018 Feb;48(2):131-139. doi: 10.1007/s00595-017-1515-9. Epub 2017 Apr 24.


Hassab's operation for Joubert syndrome with congenital hepatic fibrosis: A case report.

Miyazawa K, Hara Y, Shimizu K, Nakanishi W, Tokodai K, Nakanishi C, Miyagi S, Kawagishi N, Ohuchi N.

Int J Surg Case Rep. 2017;34:134-138. doi: 10.1016/j.ijscr.2017.03.036. Epub 2017 Mar 28.


Successful corticosteroid treatment for pleural effusion due to radiation-induced pleuritis after chemoradiotherapy in a patient with esophageal cancer.

Kumagai T, Nakano T, Matsushita H, Jingu K, Ohuchi N, Kamei T.

Int Cancer Conf J. 2017 Apr 11;6(3):138-143. doi: 10.1007/s13691-017-0293-y. eCollection 2017 Jul.


Overcoming an Extremely Drug Resistant (XDR) Pathogen: Avibactam Restores Susceptibility to Ceftazidime for Burkholderia cepacia Complex Isolates from Cystic Fibrosis Patients.

Papp-Wallace KM, Becka SA, Zeiser ET, Ohuchi N, Mojica MF, Gatta JA, Falleni M, Tosi D, Borghi E, Winkler ML, Wilson BM, LiPuma JJ, Nukaga M, Bonomo RA.

ACS Infect Dis. 2017 Jul 14;3(7):502-511. doi: 10.1021/acsinfecdis.7b00020. Epub 2017 Mar 30.


Randomized trial of aromatherapy versus conventional care for breast cancer patients during perioperative periods.

Tamaki K, Fukuyama AK, Terukina S, Kamada Y, Uehara K, Arakaki M, Yamashiro K, Miyashita M, Ishida T, McNamara KM, Ohuchi N, Tamaki N, Sasano H.

Breast Cancer Res Treat. 2017 Apr;162(3):523-531. doi: 10.1007/s10549-017-4134-7. Epub 2017 Feb 8.


Bilateral approach for thoracoscopic esophagectomy with lymph node dissection in the dorsal area of the thoracic aorta in patients with esophageal cancer: A report of two cases.

Onodera Y, Nakano T, Heishi T, Sakurai T, Taniyama Y, Sato C, Ohuchi N, Kamei T.

Int J Surg Case Rep. 2017;31:154-158. doi: 10.1016/j.ijscr.2017.01.040. Epub 2017 Jan 19.


Thoracoscopic esophageal repair with barbed suture material in a case of Boerhaave's syndrome.

Nakano T, Sato C, Sakurai T, Kamiya K, Kamei T, Ohuchi N.

J Thorac Dis. 2016 Dec;8(12):E1576-E1580. doi: 10.21037/jtd.2016.12.46.


SOX2 and Rb1 in esophageal small-cell carcinoma: their possible involvement in pathogenesis.

Ishida H, Kasajima A, Kamei T, Miura T, Oka N, Yazdani S, Ozawa Y, Fujishima F, Sakurada A, Nakamura Y, Tanaka Y, Kurosumi M, Ishikawa Y, Okada Y, Ohuchi N, Sasano H.

Mod Pathol. 2017 May;30(5):660-671. doi: 10.1038/modpathol.2016.222. Epub 2017 Jan 20.


Thoracoscopic surgery in the prone position for esophageal cancer in patients with situs inversus totalis: A report of two cases.

Nakano T, Kamei T, Onodera Y, Ujiie N, Ohuchi N.

Int J Surg Case Rep. 2017;31:43-46. doi: 10.1016/j.ijscr.2017.01.009. Epub 2017 Jan 6.


A xenogeneic-free system generating functional human gut organoids from pluripotent stem cells.

Uchida H, Machida M, Miura T, Kawasaki T, Okazaki T, Sasaki K, Sakamoto S, Ohuchi N, Kasahara M, Umezawa A, Akutsu H.

JCI Insight. 2017 Jan 12;2(1):e86492. doi: 10.1172/jci.insight.86492.


Associations of obesity and physical activity with serum and intratumoral sex steroid hormone levels among postmenopausal women with breast cancer: analysis of paired serum and tumor tissue samples.

Kakugawa Y, Tada H, Kawai M, Suzuki T, Nishino Y, Kanemura S, Ishida T, Ohuchi N, Minami Y.

Breast Cancer Res Treat. 2017 Feb;162(1):115-125. doi: 10.1007/s10549-016-4094-3. Epub 2017 Jan 2.


Aryl hydrocarbon receptor induced intratumoral aromatase in breast cancer.

Saito R, Miki Y, Hata S, Ishida T, Suzuki T, Ohuchi N, Sasano H.

Breast Cancer Res Treat. 2017 Feb;161(3):399-407. doi: 10.1007/s10549-016-4063-x. Epub 2016 Nov 30.


X-ray computed tomography imaging of a tumor with high sensitivity using gold nanoparticles conjugated to a cancer-specific antibody via polyethylene glycol chains on their surface.

Nakagawa T, Gonda K, Kamei T, Cong L, Hamada Y, Kitamura N, Tada H, Ishida T, Aimiya T, Furusawa N, Nakano Y, Ohuchi N.

Sci Technol Adv Mater. 2016 Jul 26;17(1):387-397. eCollection 2016.


Analysis of multiple primary cancer autopsy cases associated with breast cancer: 2002-2010.

Shibahara Y, Sugawara Y, Miki Y, Hata S, Takahashi H, Nakamura Y, Suzuki T, Ohuchi N, Tsuji I, Sasano H.

Pathol Int. 2016 Dec;66(12):695-700. doi: 10.1111/pin.12484. Epub 2016 Nov 22.


A laser-induced pulsed water jet for layer-selective submucosal dissection of the esophagus.

Nakano T, Sato C, Yamada M, Nakagawa A, Yamamoto H, Fujishima F, Tominaga T, Satomi S, Ohuchi N.

Laser Ther. 2016 Oct 1;25(3):185-191.


The presence and impact of estrogen metabolism on the biology of triple-negative breast cancer.

McNamara KM, Oguro S, Omata F, Kikuchi K, Guestini F, Suzuki K, Yang Y, Abe E, Hirakawa H, Brown KA, Takanori I, Ohuchi N, Sasano H.

Breast Cancer Res Treat. 2017 Jan;161(2):213-227. doi: 10.1007/s10549-016-4050-2. Epub 2016 Nov 15.


Impact of routine recurrent laryngeal nerve monitoring in prone esophagectomy with mediastinal lymph node dissection.

Hikage M, Kamei T, Nakano T, Abe S, Katsura K, Taniyama Y, Sakurai T, Teshima J, Ito S, Niizuma N, Okamoto H, Fukutomi T, Yamada M, Maruyama S, Ohuchi N.

Surg Endosc. 2017 Jul;31(7):2986-2996. doi: 10.1007/s00464-016-5317-8. Epub 2016 Nov 8.


Quantitative diagnosis of HER2 protein expressing breast cancer by single-particle quantum dot imaging.

Miyashita M, Gonda K, Tada H, Watanabe M, Kitamura N, Kamei T, Sasano H, Ishida T, Ohuchi N.

Cancer Med. 2016 Oct;5(10):2813-2824. doi: 10.1002/cam4.898. Epub 2016 Sep 26.


Surgical resection of recurrent extrahepatic hepatocellular carcinoma with tumor thrombus extending into the right atrium under cardiopulmonary bypass: a case report and review of the literature.

Ohta M, Nakanishi C, Kawagishi N, Hara Y, Maida K, Kashiwadate T, Miyazawa K, Yoshida S, Miyagi S, Hayatsu Y, Kawamoto S, Matsuda Y, Okada Y, Saiki Y, Ohuchi N.

Surg Case Rep. 2016 Dec;2(1):110. Epub 2016 Oct 11.


Postoperative hormonal therapy prevents recovery of neurological damage after surgery in patients with breast cancer.

Sekiguchi A, Sato C, Matsudaira I, Kotozaki Y, Nouchi R, Takeuchi H, Kawai M, Tada H, Ishida T, Taki Y, Ohuchi N, Kawashima R.

Sci Rep. 2016 Oct 6;6:34671. doi: 10.1038/srep34671.


Soluble Thrombomodulin Ameliorates Ischemia-Reperfusion Injury of Liver Grafts by Modulating the Proinflammatory Role of High-Mobility Group Box 1.

Kashiwadate T, Miyagi S, Hara Y, Akamatsu Y, Sekiguchi S, Kawagishi N, Ohuchi N, Satomi S.

Tohoku J Exp Med. 2016 Aug;239(4):315-23. doi: 10.1620/tjem.239.315.


Efficacy of iliac inflow repair in patients with concomitant iliac and superficial femoral artery occlusive disease.

Akamatsu D, Goto H, Kamei T, Miyagi S, Tsuchida K, Kawamura K, Tajima Y, Umetsu M, Watanabe T, Ohuchi N.

Asian J Surg. 2017 Nov;40(6):475-480. doi: 10.1016/j.asjsur.2016.07.004. Epub 2016 Jul 19.


Graft placement with an omental flap for ruptured infective common iliac aneurysm in a patient with a continuous flow left ventricular assist device: alternative surgical approach avoiding driveline injury and pathogen identification by 16S ribosomal DNA gene analysis.

Akiyama M, Hayatsu Y, Sakatsume K, Fujiwara H, Shimizu T, Akamatsu D, Kakuta R, Gu Y, Kaku M, Kumagai K, Kawamoto S, Goto H, Ohuchi N, Saiki Y.

J Artif Organs. 2016 Dec;19(4):383-386. Epub 2016 Jul 5.


The Tohoku Medical Megabank Project: Design and Mission.

Kuriyama S, Yaegashi N, Nagami F, Arai T, Kawaguchi Y, Osumi N, Sakaida M, Suzuki Y, Nakayama K, Hashizume H, Tamiya G, Kawame H, Suzuki K, Hozawa A, Nakaya N, Kikuya M, Metoki H, Tsuji I, Fuse N, Kiyomoto H, Sugawara J, Tsuboi A, Egawa S, Ito K, Chida K, Ishii T, Tomita H, Taki Y, Minegishi N, Ishii N, Yasuda J, Igarashi K, Shimizu R, Nagasaki M, Koshiba S, Kinoshita K, Ogishima S, Takai-Igarashi T, Tominaga T, Tanabe O, Ohuchi N, Shimosegawa T, Kure S, Tanaka H, Ito S, Hitomi J, Tanno K, Nakamura M, Ogasawara K, Kobayashi S, Sakata K, Satoh M, Shimizu A, Sasaki M, Endo R, Sobue K, Tohoku Medical Megabank Project Study Group T, Yamamoto M.

J Epidemiol. 2016 Sep 5;26(9):493-511. doi: 10.2188/jea.JE20150268. Epub 2016 Jul 2.


Resveratrol Prevents Warm Ischemia-Reperfusion Injury in Liver Grafts From Non-Heart-Beating Donor Rats.

Shimizu K, Miyagi S, Miyazawa K, Maida K, Kashiwadate T, Hara Y, Goto M, Kawagishi N, Ohuchi N.

Transplant Proc. 2016 May;48(4):1221-5. doi: 10.1016/j.transproceed.2015.11.031.


Relationship Between Bile Duct Reconstruction and Complications in Living Donor Liver Transplantation.

Miyagi S, Kawagishi N, Kashiwadate T, Fujio A, Tokodai K, Hara Y, Nakanishi C, Kamei T, Ohuchi N, Satomi S.

Transplant Proc. 2016 May;48(4):1166-9. doi: 10.1016/j.transproceed.2015.10.073.


The Significance of Screening for HLA Antibodies in the Long-Term Follow-up of Pediatric Liver Transplant Recipients.

Tokodai K, Kawagishi N, Miyagi S, Nakanishi C, Hara Y, Fujio A, Kashiwadate T, Maida K, Goto H, Kamei T, Ohuchi N.

Transplant Proc. 2016 May;48(4):1139-41. doi: 10.1016/j.transproceed.2015.12.081.


Poor Long-Term Outcomes of Adult Liver Transplantation Involving Elderly Living Donors.

Tokodai K, Kawagishi N, Miyagi S, Nakanishi C, Hara Y, Fujio A, Kashiwadate T, Maida K, Goto H, Kamei T, Ohuchi N.

Transplant Proc. 2016 May;48(4):1130-3. doi: 10.1016/j.transproceed.2016.01.016.


Adjunctive ultrasonography for breast cancer screening - Authors' reply.

Ohuchi N, Suzuki A, Yamamoto S, Kuriyama S, Ishida T.

Lancet. 2016 Jun 11;387(10036):2381-2. doi: 10.1016/S0140-6736(16)30670-5. No abstract available.


In situ detection of estrogen receptor dimers in breast carcinoma cells in archival materials using proximity ligation assay (PLA).

Iwabuchi E, Miki Y, Ono K, Onodera Y, Suzuki T, Hirakawa H, Ishida T, Ohuchi N, Sasano H.

J Steroid Biochem Mol Biol. 2017 Jan;165(Pt B):159-169. doi: 10.1016/j.jsbmb.2016.05.022. Epub 2016 Jun 2.


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