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Fabry disease in a Japanese population-molecular and biochemical characteristics.

Sakuraba H, Tsukimura T, Togawa T, Tanaka T, Ohtsuka T, Sato A, Shiga T, Saito S, Ohno K.

Mol Genet Metab Rep. 2018 Oct 26;17:73-79. doi: 10.1016/j.ymgmr.2018.10.004. eCollection 2018 Dec.


Demographics, safety and quality, and prognostic information in both the seventh and eighth editions of the TNM classification in 18,973 surgical cases of the Japanese Joint committee of Lung Cancer Registry database in 2010.

Okami J, Shintani Y, Okumura M, Ito H, Ohtsuka T, Toyooka S, Mori T, Watanabe SI, Date H, Yokoi K, Asamura H, Nagayasu T, Miyaoka E, Yoshino I; Japanese Joint Committee of Lung Cancer Registry.

J Thorac Oncol. 2018 Oct 10. pii: S1556-0864(18)33180-0. doi: 10.1016/j.jtho.2018.10.002. [Epub ahead of print]


Concomitant Intraductal Papillary Mucinous Neoplasm in Pancreatic Ductal Adenocarcinoma Is an Independent Predictive Factor for the Occurrence of New Cancer in the Remnant Pancreas.

Matsuda R, Miyasaka Y, Ohishi Y, Yamamoto T, Saeki K, Mochidome N, Abe A, Ozono K, Shindo K, Ohtsuka T, Kikutake C, Nakamura M, Oda Y.

Ann Surg. 2018 Oct 10. doi: 10.1097/SLA.0000000000003060. [Epub ahead of print]


The proneural bHLH genes Mash1, Math3 and NeuroD are required for pituitary development

Ando M, Goto M, Hojo M, Kita A, Kitagawa M, Ohtsuka T, Kageyama R, Miyamoto S.

J Mol Endocrinol. 2018 Oct 1;61(3):127-138. doi: 10.1530/JME-18-0090.


Learning curve and surgical factors influencing the surgical outcomes during the initial experience with laparoscopic pancreaticoduodenectomy.

Nagakawa Y, Nakamura Y, Honda G, Gotoh Y, Ohtsuka T, Ban D, Nakata K, Sahara Y, Velasquez VVD, Takaori K, Misawa T, Kuroki T, Kawai M, Morikawa T, Yamaue H, Tanabe M, Mou Y, Lee WJ, Shrikhande SV, Conrad C, Han HS, Tang CN, Palanivelu C, Kooby DA, Asbun HJ, Wakabayashi G, Tsuchida A, Takada T, Yamamoto M, Nakamura M.

J Hepatobiliary Pancreat Sci. 2018 Oct 6. doi: 10.1002/jhbp.586. [Epub ahead of print]


Dynamic control of neural stem cells by bHLH factors.

Kageyama R, Shimojo H, Ohtsuka T.

Neurosci Res. 2018 Sep 15. pii: S0168-0102(18)30379-1. doi: 10.1016/j.neures.2018.09.005. [Epub ahead of print] Review.


Prognostic Value of Preoperative Nutritional and Immunological Factors in Patients with Pancreatic Ductal Adenocarcinoma.

Abe T, Nakata K, Kibe S, Mori Y, Miyasaka Y, Ohuchida K, Ohtsuka T, Oda Y, Nakamura M.

Ann Surg Oncol. 2018 Dec;25(13):3996-4003. doi: 10.1245/s10434-018-6761-6. Epub 2018 Sep 17.


Epicardial Left Atrial Appendage Exclusion Reduces Blood Pressure in Patients With Atrial Fibrillation and Hypertension.

Turagam MK, Vuddanda V, Verberkmoes N, Ohtsuka T, Akca F, Atkins D, Bommana S, Emmert MY, Gopinathannair R, Dunnington G, Rasekh A, Cheng J, Salzberg S, Natale A, Cox J, Lakkireddy DR.

J Am Coll Cardiol. 2018 Sep 18;72(12):1346-1353. doi: 10.1016/j.jacc.2018.06.066.


Cytomatrix proteins CAST and ELKS regulate retinal photoreceptor development and maintenance.

Hagiwara A, Kitahara Y, Grabner CP, Vogl C, Abe M, Kitta R, Ohta K, Nakamura K, Sakimura K, Moser T, Nishi A, Ohtsuka T.

J Cell Biol. 2018 Nov 5;217(11):3993-4006. doi: 10.1083/jcb.201704076. Epub 2018 Sep 6.


[Staged Hybrid Treatment for a Coronary Artery Pseudoaneurysm after Percutaneous Coronary Intervention;Report of a Case].

Arima D, Hisagi M, Nonaka T, Ninomiya M, Ohtsuka T.

Kyobu Geka. 2018 Sep;71(9):693-695. Japanese.


Adipose tissue-derived stromal cells are sources of cancer-associated fibroblasts and enhance tumor progression by dense collagen matrix.

Okumura T, Ohuchida K, Kibe S, Iwamoto C, Ando Y, Takesue S, Nakayama H, Abe T, Endo S, Koikawa K, Sada M, Horioka K, Mochidome N, Arita M, Moriyama T, Nakata K, Miyasaka Y, Ohtsuka T, Mizumoto K, Oda Y, Hashizume M, Nakamura M.

Int J Cancer. 2018 Aug 28. doi: 10.1002/ijc.31775. [Epub ahead of print]


En Bloc Left Pulmonary Vein and Appendage Isolation in Thoracoscopic Surgery for Atrial Fibrillation.

Ohtsuka T, Nonaka T, Hisagi M, Ninomiya M.

Ann Thorac Surg. 2018 Nov;106(5):1340-1347. doi: 10.1016/j.athoracsur.2018.06.065. Epub 2018 Aug 14.


Difficulty scoring system in laparoscopic distal pancreatectomy.

Ohtsuka T, Ban D, Nakamura Y, Nagakawa Y, Tanabe M, Gotoh Y, Velasquez VVDM, Nakata K, Sahara Y, Takaori K, Honda G, Misawa T, Kawai M, Yamaue H, Morikawa T, Kuroki T, Mou Y, Lee WJ, Shrikhande SV, Tang CN, Conrad C, Han HS, Palanivelu C, Asbun HJ, Kooby DA, Wakabayashi G, Takada T, Yamamoto M, Nakamura M.

J Hepatobiliary Pancreat Sci. 2018 Aug 17. doi: 10.1002/jhbp.578. [Epub ahead of print]


Intrapancreatic recurrence of intraductal tubulopapillary neoplasm (ITPN) 16 years after the initial surgery for noninvasive ITPN: a case report.

Saeki K, Miyasaka Y, Ohishi Y, Yamamoto T, Matsuda R, Mochidome N, Mori Y, Nakata K, Ohtsuka T, Ishigami K, Minoda Y, Koga Y, Oda Y, Nakamura M.

Surg Case Rep. 2018 Aug 16;4(1):96. doi: 10.1186/s40792-018-0497-1.


CAST/ELKS Proteins Control Voltage-Gated Ca2+ Channel Density and Synaptic Release Probability at a Mammalian Central Synapse.

Dong W, Radulovic T, Goral RO, Thomas C, Suarez Montesinos M, Guerrero-Given D, Hagiwara A, Putzke T, Hida Y, Abe M, Sakimura K, Kamasawa N, Ohtsuka T, Young SM Jr.

Cell Rep. 2018 Jul 10;24(2):284-293.e6. doi: 10.1016/j.celrep.2018.06.024.


Minimally invasive preservation versus splenectomy during distal pancreatectomy: a systematic review and meta-analysis.

Nakata K, Shikata S, Ohtsuka T, Ukai T, Miyasaka Y, Mori Y, Velasquez VVDM, Gotoh Y, Ban D, Nakamura Y, Nagakawa Y, Tanabe M, Sahara Y, Takaori K, Honda G, Misawa T, Kawai M, Yamaue H, Morikawa T, Kuroki T, Mou Y, Lee WJ, Shrikhande SV, Tang CN, Conrad C, Han HS, Chinnusamy P, Asbun HJ, Kooby DA, Wakabayashi G, Takada T, Yamamoto M, Nakamura M.

J Hepatobiliary Pancreat Sci. 2018 Jun 26. doi: 10.1002/jhbp.569. [Epub ahead of print]


Application of ultrasonography to high-tie and low-tie vascular ligation of the inferior mesenteric artery in laparoscopic colorectal cancer surgery: technical notes.

Sadakari Y, Nagai S, Velasquez VV, Nagayoshi K, Fujita H, Ohuchida K, Manabe T, Ohtsuka T, Nakamura M.

Surg Endosc. 2018 Jun 25. doi: 10.1007/s00464-018-6302-1. [Epub ahead of print]


The proneural bHLH genes Mash1, Math3 and NeuroD are required for pituitary development.

Ando M, Goto M, Hojo M, Kita A, Kitagawa M, Ohtsuka T, Kageyama R, Miyamoto S.

J Mol Endocrinol. 2018 Jun 25. pii: JME-18-0090. doi: 10.1530/JME-18-0090. [Epub ahead of print]


Neuroendocrine tumor of the pancreas with rhabdoid feature.

Miyazaki T, Aishima S, Fujino M, Ozono K, Kubo Y, Ushijima Y, Osoegawa T, Ihara E, Tetsuhide I, Ohtsuka T, Nakamura M, Oda Y.

Virchows Arch. 2018 Jun 24. doi: 10.1007/s00428-018-2398-x. [Epub ahead of print]


Preoperative Muscle Volume Predicts Graft Survival After Pancreas Transplantation: A Retrospective Observational Cohort Study.

Noguchi H, Miyasaka Y, Kaku K, Kurihara K, Nakamura U, Okabe Y, Ohtsuka T, Ishigami K, Nakamura M.

Transplant Proc. 2018 Jun;50(5):1482-1488. doi: 10.1016/j.transproceed.2018.03.018. Epub 2018 Mar 12.


Comparison of guidelines for intraductal papillary mucinous neoplasm: What is the next step beyond the current guidelines?

Nakamura M, Miyasaka Y, Sadakari Y, Date K, Ohtsuka T.

Ann Gastroenterol Surg. 2017 Jun 16;1(2):90-98. doi: 10.1002/ags3.12012. eCollection 2017 Jun. Review.


Thoracoscopic stapler-and-loop technique for left atrial appendage closure in nonvalvular atrial fibrillation: Mid-term outcomes in 201 patients.

Ohtsuka T, Nonaka T, Hisagi M, Ninomiya M, Masukawa A, Ota T.

Heart Rhythm. 2018 Sep;15(9):1314-1320. doi: 10.1016/j.hrthm.2018.05.026. Epub 2018 May 24.


Role of SpyGlass-DStm in the preoperative assessment of pancreatic intraductal papillary mucinous neoplasm involving the main pancreatic duct.

Ohtsuka T, Gotoh Y, Nakashima Y, Okayama Y, Nakamura S, Morita M, Aly MYF, Velasquez VVDM, Mori Y, Sadakari Y, Nakata K, Miyasaka Y, Ishigami K, Fujimori N, Mochidome N, Oda Y, Shimizu S, Nakamura M.

Pancreatology. 2018 Apr 30. pii: S1424-3903(18)30079-6. doi: 10.1016/j.pan.2018.04.012. [Epub ahead of print]


Basement membrane destruction by pancreatic stellate cells leads to local invasion in pancreatic ductal adenocarcinoma.

Koikawa K, Ohuchida K, Ando Y, Kibe S, Nakayama H, Takesue S, Endo S, Abe T, Okumura T, Iwamoto C, Moriyama T, Nakata K, Miyasaka Y, Ohtsuka T, Nagai E, Mizumoto K, Hashizume M, Nakamura M.

Cancer Lett. 2018 Jul 1;425:65-77. doi: 10.1016/j.canlet.2018.03.031. Epub 2018 Mar 23.


The presynaptic active zone: molecules, plasticity, and diseases.

Sigrist S, Ohtsuka T.

Neurosci Res. 2018 Feb;127:1-2. doi: 10.1016/j.neures.2018.01.004. No abstract available.


Feasibility of Prophylactic Pancreatojejunostomy in Possible High-Risk Patients for Prevention of Pancreatic Fistula during Enucleation or Limited Pancreatic Resection.

Ohtsuka T, Mori Y, Fujimoto T, Miyasaka Y, Nakata K, Ohuchida K, Nagai E, Oda Y, Shimizu S, Nakamura M.

Am Surg. 2018 Jan 1;84(1):149-153.


Mutations in bassoon in individuals with familial and sporadic progressive supranuclear palsy-like syndrome.

Yabe I, Yaguchi H, Kato Y, Miki Y, Takahashi H, Tanikawa S, Shirai S, Takahashi I, Kimura M, Hama Y, Matsushima M, Fujioka S, Kano T, Watanabe M, Nakagawa S, Kunieda Y, Ikeda Y, Hasegawa M, Nishihara H, Ohtsuka T, Tanaka S, Tsuboi Y, Hatakeyama S, Wakabayashi K, Sasaki H.

Sci Rep. 2018 Jan 16;8(1):819. doi: 10.1038/s41598-018-19198-0.


Synaptic localisation of SRF coactivators, MKL1 and MKL2, and their role in dendritic spine morphology.

Kaneda M, Sakagami H, Hida Y, Ohtsuka T, Satou N, Ishibashi Y, Fukuchi M, Krysiak A, Ishikawa M, Ihara D, Kalita K, Tabuchi A.

Sci Rep. 2018 Jan 15;8(1):727. doi: 10.1038/s41598-017-18905-7.


CAST: Its molecular structure and phosphorylation-dependent regulation of presynaptic plasticity.

Hamada S, Ohtsuka T.

Neurosci Res. 2018 Feb;127:25-32. doi: 10.1016/j.neures.2017.12.005. Epub 2017 Dec 21. Review.


[A case of cardiogenic embolism, which occurred under appropriate warfarin use, treated with thoracoscopic left atrial appendectomy].

Kikuno M, Koga M, Kume Y, Ohtsuka T, Hayakawa M, Toyoda K.

Rinsho Shinkeigaku. 2018 Jan 26;58(1):9-14. doi: 10.5692/ Epub 2017 Dec 22. Japanese.


Surveillance of patients with intraductal papillary mucinous neoplasm with and without pancreatectomy with special reference to the incidence of concomitant pancreatic ductal adenocarcinoma.

Date K, Ohtsuka T, Nakamura S, Mochidome N, Mori Y, Miyasaka Y, Oda Y, Nakamura M.

Surgery. 2018 Feb;163(2):291-299. doi: 10.1016/j.surg.2017.09.040. Epub 2017 Dec 6.


Differential Diagnosis of Pancreatic Epidermoid Cyst Without a Solid Component (Residual Splenic Tissue) vs. Mucinous Cystic Neoplasm.

Ishigami K, Nishie A, Irie H, Asayama Y, Ushijima Y, Takayama Y, Okamoto D, Fujita N, Ohtsuka T, Ito T, Mochidome N, Honda H.

J Gastrointest Cancer. 2017 Dec 7. doi: 10.1007/s12029-017-0035-6. [Epub ahead of print]


Multicenter study of early pancreatic cancer in Japan.

Kanno A, Masamune A, Hanada K, Maguchi H, Shimizu Y, Ueki T, Hasebe O, Ohtsuka T, Nakamura M, Takenaka M, Kitano M, Kikuyama M, Gabata T, Yoshida K, Sasaki T, Serikawa M, Furukawa T, Yanagisawa A, Shimosegawa T; Japan Study Group on the Early Detection of Pancreatic Cancer (JEDPAC).

Pancreatology. 2018 Jan;18(1):61-67. doi: 10.1016/j.pan.2017.11.007. Epub 2017 Nov 20.


Pancreatic stellate cells reorganize matrix components and lead pancreatic cancer invasion via the function of Endo180.

Koikawa K, Ohuchida K, Takesue S, Ando Y, Kibe S, Nakayama H, Endo S, Abe T, Okumura T, Horioka K, Sada M, Iwamoto C, Moriyama T, Nakata K, Miyasaka Y, Ohuchida R, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Hashizume M, Nakamura M.

Cancer Lett. 2018 Jan 1;412:143-154. doi: 10.1016/j.canlet.2017.10.010. Epub 2017 Oct 20.


S100P in Duodenal Fluid Is a Useful Diagnostic Marker for Pancreatic Ductal Adenocarcinoma.

Matsunaga T, Ohtsuka T, Asano K, Kimura H, Ohuchida K, Kitada H, Ideno N, Mori Y, Tokunaga S, Oda Y, Guha S, Raimondo M, Nakamura M, Tanaka M.

Pancreas. 2017 Nov/Dec;46(10):1288-1295. doi: 10.1097/MPA.0000000000000940.


Estimation of age-related DNA degradation from formalin-fixed and paraffin-embedded tissue according to the extraction methods.

Watanabe M, Hashida S, Yamamoto H, Matsubara T, Ohtsuka T, Suzawa K, Maki Y, Soh J, Asano H, Tsukuda K, Toyooka S, Miyoshi S.

Exp Ther Med. 2017 Sep;14(3):2683-2688. doi: 10.3892/etm.2017.4797. Epub 2017 Jul 17.


Determination of poor prognostic immune features of tumour microenvironment in non-smoking patients with lung adenocarcinoma.

Kinoshita T, Kudo-Saito C, Muramatsu R, Fujita T, Saito M, Nagumo H, Sakurai T, Noji S, Takahata E, Yaguchi T, Tsukamoto N, Hayashi Y, Kaseda K, Kamiyama I, Ohtsuka T, Tomizawa K, Shimoji M, Mitsudomi T, Asamura H, Kawakami Y.

Eur J Cancer. 2017 Nov;86:15-27. doi: 10.1016/j.ejca.2017.08.026. Epub 2017 Sep 23.


Autophagy inhibition enhances antiproliferative effect of salinomycin in pancreatic cancer cells.

Endo S, Nakata K, Sagara A, Koikawa K, Ando Y, Kibe S, Takesue S, Nakayama H, Abe T, Okumura T, Moriyama T, Miyasaka Y, Ohuchida K, Ohtsuka T, Mizumoto K, Nakamura M.

Pancreatology. 2017 Nov - Dec;17(6):990-996. doi: 10.1016/j.pan.2017.08.009. Epub 2017 Aug 25.


Degree of desmoplasia in metastatic lymph node lesions is associated with lesion size and poor prognosis in pancreatic cancer patients.

Nakayama H, Ohuchida K, Yoshida M, Miyazaki T, Takesue S, Abe T, Endo S, Koikawa K, Okumura T, Moriyama T, Nakata K, Miyasaka Y, Shirahane K, Manabe T, Ohtsuka T, Toma H, Tominaga Y, Nagai E, Mizumoto K, Oda Y, Nakamura M.

Oncol Lett. 2017 Sep;14(3):3141-3147. doi: 10.3892/ol.2017.6549. Epub 2017 Jul 8.


Hes5 regulates the transition timing of neurogenesis and gliogenesis in mammalian neocortical development.

Bansod S, Kageyama R, Ohtsuka T.

Development. 2017 Sep 1;144(17):3156-3167. doi: 10.1242/dev.147256.


Successful video-assisted thoracoscopic surgery in prone position in patients with esophageal cancer and aberrant right subclavian artery: report of three cases.

Shindo K, Nagai E, Nabae T, Eguchi T, Moriyama T, Ohuchida K, Manabe T, Ohtsuka T, Oda Y, Hashizume M, Nakamura M.

Surg Case Rep. 2017 Dec;3(1):86. doi: 10.1186/s40792-017-0360-9. Epub 2017 Jul 28.


Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.

Tanaka M, Fernández-Del Castillo C, Kamisawa T, Jang JY, Levy P, Ohtsuka T, Salvia R, Shimizu Y, Tada M, Wolfgang CL.

Pancreatology. 2017 Sep - Oct;17(5):738-753. doi: 10.1016/j.pan.2017.07.007. Epub 2017 Jul 13. Review.


The prevalence of transpancreatic common hepatic artery and coexisting variant anatomy.

Ishigami K, Nishie A, Asayama Y, Ushijima Y, Takayama Y, Okamoto D, Fujita N, Yoshizumi T, Harimoto N, Ohtsuka T, Nakata K, Honda H.

Clin Anat. 2018 May;31(4):598-604. doi: 10.1002/ca.22957. Epub 2017 Dec 8.


Primary Recurrence in the Lung is Related to Favorable Prognosis in Patients with Pancreatic Cancer and Postoperative Recurrence.

Zheng B, Ohuchida K, Yan Z, Okumura T, Ohtsuka T, Nakamura M.

World J Surg. 2017 Nov;41(11):2858-2866. doi: 10.1007/s00268-017-4068-6.


Feasibility and safety of modified inverted T-shaped method using linear stapler with movable cartridge fork for esophagojejunostomy following laparoscopic total gastrectomy.

Ohuchida K, Nagai E, Moriyama T, Shindo K, Manabe T, Ohtsuka T, Shimizu S, Nakamura M.

Transl Gastroenterol Hepatol. 2017 May 23;2:50. doi: 10.21037/tgh.2017.04.08. eCollection 2017.


Laparoscopy-Assisted Spleen-Preserving Distal Pancreatectomy for Living-Donor Pancreas Transplantation.

Date S, Noguchi H, Kaku K, Kurihara K, Miyasaka Y, Okabe Y, Nakamura U, Ohtsuka T, Nakamura M.

Transplant Proc. 2017 Jun;49(5):1133-1137. doi: 10.1016/j.transproceed.2017.03.037.


Clinical and pathological characteristics of EGFR mutation in operable early-stage lung adenocarcinoma.

Yotsukura M, Yasuda H, Shigenobu T, Kaseda K, Masai K, Hayashi Y, Hishida T, Ohtsuka T, Naoki K, Soejima K, Betsuyaku T, Asamura H.

Lung Cancer. 2017 Jul;109:45-51. doi: 10.1016/j.lungcan.2017.04.014. Epub 2017 Apr 23.


Mucinous nonneoplastic cyst of the pancreas: CT and MRI appearances.

Ishigami K, Nishie A, Mochidome N, Asayama Y, Ushijima Y, Kakihara D, Okamoto D, Fujita N, Ohtsuka T, Miyasaka Y, Hida T, Yoshizumi T, Honda H.

Abdom Radiol (NY). 2017 Dec;42(12):2827-2834. doi: 10.1007/s00261-017-1204-6.


Laparoscopic surgery for congenital biliary dilatation: a single-institution experience.

Aly MYF, Mori Y, Miyasaka Y, Ohtsuka T, Sadakari Y, Nakata K, Oda Y, Shimizu S, Nakamura M.

Surg Today. 2018 Jan;48(1):44-50. doi: 10.1007/s00595-017-1545-3. Epub 2017 May 29.


Extra-pancreatic invasion induces lipolytic and fibrotic changes in the adipose microenvironment, with released fatty acids enhancing the invasiveness of pancreatic cancer cells.

Okumura T, Ohuchida K, Sada M, Abe T, Endo S, Koikawa K, Iwamoto C, Miura D, Mizuuchi Y, Moriyama T, Nakata K, Miyasaka Y, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Oda Y, Hashizume M, Nakamura M.

Oncotarget. 2017 Mar 14;8(11):18280-18295. doi: 10.18632/oncotarget.15430.

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