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Items: 1 to 50 of 125

1.

Effects of storage temperature, storage time, and Cary-Blair transport medium on the stability of the gut microbiota.

Nagata N, Tohya M, Takeuchi F, Suda W, Nishijima S, Ohsugi M, Ueki K, Tsujimoto T, Nakamura T, Kawai T, Miyoshi-Akiyama T, Uemura N, Hattori M.

Drug Discov Ther. 2019 Oct 11. doi: 10.5582/ddt.2019.01071. [Epub ahead of print]

PMID:
31611489
2.

Development of Patient State Model to Overview Clinical Registry Database.

Ishii M, Miyo K, Sugiyama T, Ohsugi M, Ueki K.

Stud Health Technol Inform. 2019 Aug 21;264:1492-1493. doi: 10.3233/SHTI190500.

PMID:
31438197
3.

Poorly controlled type 2 diabetes with no progression of diabetes-related complications and low levels of advanced glycation end products: A Case report.

Nakamura T, Tsujimoto T, Yasuda K, Chujo D, Ohsugi M, Tanabe A, Ueki K, Kajio H.

Medicine (Baltimore). 2019 Jul;98(30):e16573. doi: 10.1097/MD.0000000000016573.

4.

Variation in process quality measures of diabetes care by region and institution in Japan during 2015-2016: An observational study of nationwide claims data.

Sugiyama T, Imai K, Ihana-Sugiyama N, Tanaka H, Yanagisawa-Sugita A, Sasako T, Higashi T, Okamura T, Yamauchi T, Ueki K, Ohsugi M, Kadowaki T.

Diabetes Res Clin Pract. 2019 Sep;155:107750. doi: 10.1016/j.diabres.2019.05.029. Epub 2019 Jun 20.

5.

Comparison of effectiveness and drug cost between dipeptidyl peptidase-4 inhibitor and biguanide as the first-line anti-hyperglycaemic medication among Japanese working generation with type 2 diabetes.

Ihana-Sugiyama N, Sugiyama T, Tanaka H, Ueki K, Kobayashi Y, Ohsugi M.

J Eval Clin Pract. 2019 Jun 3. doi: 10.1111/jep.13171. [Epub ahead of print]

PMID:
31161662
6.

Effects of bowel preparation on the human gut microbiome and metabolome.

Nagata N, Tohya M, Fukuda S, Suda W, Nishijima S, Takeuchi F, Ohsugi M, Tsujimoto T, Nakamura T, Shimomura A, Yanagisawa N, Hisada Y, Watanabe K, Imbe K, Akiyama J, Mizokami M, Miyoshi-Akiyama T, Uemura N, Hattori M.

Sci Rep. 2019 Mar 11;9(1):4042. doi: 10.1038/s41598-019-40182-9.

7.

Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism.

Sasako T, Ohsugi M, Kubota N, Itoh S, Okazaki Y, Terai A, Kubota T, Yamashita S, Nakatsukasa K, Kamura T, Iwayama K, Tokuyama K, Kiyonari H, Furuta Y, Shibahara J, Fukayama M, Enooku K, Okushin K, Tsutsumi T, Tateishi R, Tobe K, Asahara H, Koike K, Kadowaki T, Ueki K.

Nat Commun. 2019 Feb 27;10(1):947. doi: 10.1038/s41467-019-08591-6.

8.

Changes in the quality of diabetes care in Japan between 2007 and 2015: A repeated cross-sectional study using claims data.

Tanaka H, Sugiyama T, Ihana-Sugiyama N, Ueki K, Kobayashi Y, Ohsugi M.

Diabetes Res Clin Pract. 2019 Mar;149:188-199. doi: 10.1016/j.diabres.2019.02.001. Epub 2019 Feb 8.

9.

Search for K_{L}→π^{0}νν[over ¯] and K_{L}→π^{0}X^{0} Decays at the J-PARC KOTO Experiment.

Ahn JK, Beckford B, Beechert J, Bryant K, Campbell M, Chen SH, Comfort J, Dona K, Hara N, Haraguchi H, Hsiung YB, Hutcheson M, Inagaki T, Kamiji I, Kawasaki N, Kim EJ, Kim JL, Kim YJ, Ko JW, Komatsubara TK, Kotera K, Kurilin AS, Lee JW, Lim GY, Lin C, Lin Q, Luo Y, Ma J, Maeda Y, Mari T, Masuda T, Matsumura T, Mcfarland D, McNeal N, Micallef J, Miyazaki K, Murayama R, Naito D, Nakagiri K, Nanjo H, Nishimiya H, Nomura T, Ohsugi M, Okuno H, Sasaki M, Sasao N, Sato K, Sato T, Sato Y, Schamis H, Seki S, Shimizu N, Shimogawa T, Shinkawa T, Shinohara S, Shiomi K, Su S, Sugiyama Y, Suzuki S, Tajima Y, Taylor M, Tecchio M, Togawa M, Tung YC, Wah YW, Watanabe H, Woo JK, Yamanaka T, Yoshida HY; KOTO Collaboration.

Phys Rev Lett. 2019 Jan 18;122(2):021802. doi: 10.1103/PhysRevLett.122.021802.

PMID:
30720307
10.

Evaluation of cellular and humoral autoimmunity before the development of type 1 diabetes in a patient with idiopathic CD4 lymphocytopenia.

Maruyama K, Chujo D, Watanabe K, Kawabe A, Sugiyama T, Ohsugi M, Tanabe A, Ueki K, Kajio H.

J Diabetes Investig. 2019 Jul;10(4):1108-1111. doi: 10.1111/jdi.12997. Epub 2019 Feb 25.

11.

RSK-MASTL Pathway Delays Meiotic Exit in Mouse Zygotes to Ensure Paternal Chromosome Stability.

Soeda S, Yamada-Nomoto K, Michiue T, Ohsugi M.

Dev Cell. 2018 Nov 5;47(3):363-376.e5. doi: 10.1016/j.devcel.2018.09.011. Epub 2018 Oct 4.

PMID:
30293837
13.

The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis.

Kobayashi M, Ohsugi M, Sasako T, Awazawa M, Umehara T, Iwane A, Kobayashi N, Okazaki Y, Kubota N, Suzuki R, Waki H, Horiuchi K, Hamakubo T, Kodama T, Aoe S, Tobe K, Kadowaki T, Ueki K.

Mol Cell Biol. 2018 Jul 30;38(16). pii: e00116-18. doi: 10.1128/MCB.00116-18. Print 2018 Aug 15.

14.

Design of and rationale for the Japan Diabetes compREhensive database project based on an Advanced electronic Medical record System (J-DREAMS).

Sugiyama T, Miyo K, Tsujimoto T, Kominami R, Ohtsu H, Ohsugi M, Waki K, Noguchi T, Ohe K, Kadowaki T, Kasuga M, Ueki K, Kajio H.

Diabetol Int. 2017 Jun 27;8(4):375-382. doi: 10.1007/s13340-017-0326-y. eCollection 2017 Nov.

15.

Mitotic chromosome assembly despite nucleosome depletion in Xenopus egg extracts.

Shintomi K, Inoue F, Watanabe H, Ohsumi K, Ohsugi M, Hirano T.

Science. 2017 Jun 23;356(6344):1284-1287. doi: 10.1126/science.aam9702. Epub 2017 May 18.

PMID:
28522692
16.

Efficacy and safety of sitagliptin as compared with glimepiride in Japanese patients with type 2 diabetes mellitus aged ≥ 60 years (START-J trial).

Terauchi Y, Yamada Y, Ishida H, Ohsugi M, Kitaoka M, Satoh J, Yabe D, Shihara N, Seino Y.

Diabetes Obes Metab. 2017 Aug;19(8):1188-1192. doi: 10.1111/dom.12933. Epub 2017 Apr 12.

17.

The microtubule-binding and coiled-coil domains of Kid are required to turn off the polar ejection force at anaphase.

Soeda S, Yamada-Nomoto K, Ohsugi M.

J Cell Sci. 2016 Oct 1;129(19):3609-3619. Epub 2016 Aug 22.

18.

Human TUBG2 gene is expressed as two splice variant mRNA and involved in cell growth.

Ohashi T, Yamamoto T, Yamanashi Y, Ohsugi M.

FEBS Lett. 2016 Apr;590(8):1053-63. doi: 10.1002/1873-3468.12163. Epub 2016 Apr 6.

20.

Partitioning of organophosphorus pesticides into phosphatidylcholine small unilamellar vesicles studied by second-derivative spectrophotometry.

Takegami S, Kitamura K, Ohsugi M, Ito A, Kitade T.

Spectrochim Acta A Mol Biomol Spectrosc. 2015 Jun 15;145:198-202. doi: 10.1016/j.saa.2015.02.061. Epub 2015 Mar 3.

PMID:
25775945
21.

DBTMEE: a database of transcriptome in mouse early embryos.

Park SJ, Shirahige K, Ohsugi M, Nakai K.

Nucleic Acids Res. 2015 Jan;43(Database issue):D771-6. doi: 10.1093/nar/gku1001. Epub 2014 Oct 21.

22.

Ethnic differences in insulin sensitivity, β-cell function, and hepatic extraction between Japanese and Caucasians: a minimal model analysis.

Møller JB, Dalla Man C, Overgaard RV, Ingwersen SH, Tornøe CW, Pedersen M, Tanaka H, Ohsugi M, Ueki K, Lynge J, Vasconcelos NM, Pedersen BK, Kadowaki T, Cobelli C.

J Clin Endocrinol Metab. 2014 Nov;99(11):4273-80. doi: 10.1210/jc.2014-1724. Epub 2014 Aug 13.

PMID:
25119313
23.

Deregulation of pancreas-specific oxidoreductin ERO1β in the pathogenesis of diabetes mellitus.

Awazawa M, Futami T, Sakada M, Kaneko K, Ohsugi M, Nakaya K, Terai A, Suzuki R, Koike M, Uchiyama Y, Kadowaki T, Ueki K.

Mol Cell Biol. 2014 Apr;34(7):1290-9. doi: 10.1128/MCB.01647-13. Epub 2014 Jan 27.

24.

Inferring the choreography of parental genomes during fertilization from ultralarge-scale whole-transcriptome analysis.

Park SJ, Komata M, Inoue F, Yamada K, Nakai K, Ohsugi M, Shirahige K.

Genes Dev. 2013 Dec 15;27(24):2736-48. doi: 10.1101/gad.227926.113.

25.

Body composition is the main determinant for the difference in type 2 diabetes pathophysiology between Japanese and Caucasians.

Møller JB, Pedersen M, Tanaka H, Ohsugi M, Overgaard RV, Lynge J, Almind K, Vasconcelos NM, Poulsen P, Keller C, Ueki K, Ingwersen SH, Pedersen BK, Kadowaki T.

Diabetes Care. 2014;37(3):796-804. doi: 10.2337/dc13-0598. Epub 2013 Oct 15.

PMID:
24130359
26.

Inactivation of mitogen-activated protein kinase is neither necessary nor sufficient for the onset of pronuclear formation in mouse oocytes.

Soeda S, Yamada K, Ohsugi M.

Genes Cells. 2013 Oct;18(10):850-8. doi: 10.1111/gtc.12080. Epub 2013 Jul 15.

27.

Depletion of homeodomain-interacting protein kinase 3 impairs insulin secretion and glucose tolerance in mice.

Shojima N, Hara K, Fujita H, Horikoshi M, Takahashi N, Takamoto I, Ohsugi M, Aburatani H, Noda M, Kubota N, Yamauchi T, Ueki K, Kadowaki T.

Diabetologia. 2012 Dec;55(12):3318-30. doi: 10.1007/s00125-012-2711-1. Epub 2012 Sep 16.

PMID:
22983607
28.

The effectiveness of liraglutide in nonalcoholic fatty liver disease patients with type 2 diabetes mellitus compared to sitagliptin and pioglitazone.

Ohki T, Isogawa A, Iwamoto M, Ohsugi M, Yoshida H, Toda N, Tagawa K, Omata M, Koike K.

ScientificWorldJournal. 2012;2012:496453. doi: 10.1100/2012/496453. Epub 2012 Aug 13.

29.

Poly-ADP ribosylation of Miki by tankyrase-1 promotes centrosome maturation.

Ozaki Y, Matsui H, Asou H, Nagamachi A, Aki D, Honda H, Yasunaga S, Takihara Y, Yamamoto T, Izumi S, Ohsugi M, Inaba T.

Mol Cell. 2012 Sep 14;47(5):694-706. doi: 10.1016/j.molcel.2012.06.033. Epub 2012 Aug 2.

30.

Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation.

Eguchi K, Manabe I, Oishi-Tanaka Y, Ohsugi M, Kono N, Ogata F, Yagi N, Ohto U, Kimoto M, Miyake K, Tobe K, Arai H, Kadowaki T, Nagai R.

Cell Metab. 2012 Apr 4;15(4):518-33. doi: 10.1016/j.cmet.2012.01.023. Epub 2012 Mar 29.

31.

Control of beta cell function and proliferation in mice stimulated by small-molecule glucokinase activator under various conditions.

Nakamura A, Togashi Y, Orime K, Sato K, Shirakawa J, Ohsugi M, Kubota N, Kadowaki T, Terauchi Y.

Diabetologia. 2012 Jun;55(6):1745-54. doi: 10.1007/s00125-012-2521-5. Epub 2012 Mar 29.

PMID:
22456697
32.

Involvement of CNOT3 in mitotic progression through inhibition of MAD1 expression.

Takahashi A, Kikuguchi C, Morita M, Shimodaira T, Tokai-Nishizumi N, Yokoyama K, Ohsugi M, Suzuki T, Yamamoto T.

Biochem Biophys Res Commun. 2012 Mar 9;419(2):268-73. doi: 10.1016/j.bbrc.2012.02.007. Epub 2012 Feb 10.

PMID:
22342980
33.

Impact of diabetes among revascularized patients in Japan and the U.S.

Kohsaka S, Goto M, Nagai T, Lee VV, Elayda M, Furukawa Y, Fukushima M, Komeda M, Sakata R, Ohsugi M, Fukuda K, Wilson JM, Kita T, Kimura T.

Diabetes Care. 2012 Mar;35(3):654-9. doi: 10.2337/dc11-1547. Epub 2012 Feb 1.

34.

Microtubule stabilization triggers the plus-end accumulation of Kif18A/kinesin-8.

Masuda N, Shimodaira T, Shiu SJ, Tokai-Nishizumi N, Yamamoto T, Ohsugi M.

Cell Struct Funct. 2011;36(2):261-7. Epub 2011 Nov 19.

35.

Complete kinetochore tracking reveals error-prone homologous chromosome biorientation in mammalian oocytes.

Kitajima TS, Ohsugi M, Ellenberg J.

Cell. 2011 Aug 19;146(4):568-81. doi: 10.1016/j.cell.2011.07.031. Erratum in: Cell. 2011 Sep 16;146(6):1042.

36.

[Emerging GLP-1 analogues and dipeptidyl peptidase 4(DPP-4) inhibitors].

Ohsugi M.

Nihon Rinsho. 2011 May;69(5):895-901. Review. Japanese.

PMID:
21595278
37.

[The use of new agents enhancing incretin effects for patients with diabetes in Japan].

Ohsugi M, Kadowaki T.

Nihon Rinsho. 2011 May;69(5):771-94. Review. Japanese. No abstract available.

PMID:
21595260
38.

Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway.

Awazawa M, Ueki K, Inabe K, Yamauchi T, Kubota N, Kaneko K, Kobayashi M, Iwane A, Sasako T, Okazaki Y, Ohsugi M, Takamoto I, Yamashita S, Asahara H, Akira S, Kasuga M, Kadowaki T.

Cell Metab. 2011 Apr 6;13(4):401-412. doi: 10.1016/j.cmet.2011.02.010.

39.

Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance.

Kobayashi N, Ueki K, Okazaki Y, Iwane A, Kubota N, Ohsugi M, Awazawa M, Kobayashi M, Sasako T, Kaneko K, Suzuki M, Nishikawa Y, Hara K, Yoshimura K, Koshima I, Goyama S, Murakami K, Sasaki J, Nagai R, Kurokawa M, Sasaki T, Kadowaki T.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5753-8. doi: 10.1073/pnas.1016430108. Epub 2011 Mar 21.

40.

Class IA phosphatidylinositol 3-kinase in pancreatic β cells controls insulin secretion by multiple mechanisms.

Kaneko K, Ueki K, Takahashi N, Hashimoto S, Okamoto M, Awazawa M, Okazaki Y, Ohsugi M, Inabe K, Umehara T, Yoshida M, Kakei M, Kitamura T, Luo J, Kulkarni RN, Kahn CR, Kasai H, Cantley LC, Kadowaki T.

Cell Metab. 2010 Dec 1;12(6):619-32. doi: 10.1016/j.cmet.2010.11.005.

41.

Decreased insulin secretion and accumulation of triglyceride in beta cells overexpressing a dominant-negative form of AMP-activated protein kinase.

Okazaki Y, Eto K, Yamashita T, Okamoto M, Ohsugi M, Noda M, Terauchi Y, Ueki K, Kadowaki T.

Endocr J. 2010;57(2):141-52. Epub 2009 Nov 19.

42.

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity.

Nishimura S, Manabe I, Nagasaki M, Eto K, Yamashita H, Ohsugi M, Otsu M, Hara K, Ueki K, Sugiura S, Yoshimura K, Kadowaki T, Nagai R.

Nat Med. 2009 Aug;15(8):914-20. doi: 10.1038/nm.1964. Epub 2009 Jul 26.

PMID:
19633658
43.

Reconsideration of insulin signals induced by improved laboratory animal diets, Japanese and American diets, in IRS-2 deficient mice.

Hashimoto H, Arai T, Mori A, Kawai K, Hikishima K, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Okano H, Yamauchi T, Kubota N, Ueki K, Tobe K, Tamaoki N, Kadowaki T, Kosaka K.

Exp Clin Endocrinol Diabetes. 2009 Nov;117(10):577-86. doi: 10.1055/s-0029-1225352. Epub 2009 Jul 23.

PMID:
19629935
44.

Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation.

Oshimori N, Li X, Ohsugi M, Yamamoto T.

EMBO J. 2009 Jul 22;28(14):2066-76. doi: 10.1038/emboj.2009.161. Epub 2009 Jun 18.

45.

Facile and efficient synthesis of naturally occurring carbasugars (+)-pericosines A and C.

Usami Y, Ohsugi M, Mizuki K, Ichikawa H, Arimoto M.

Org Lett. 2009 Jun 18;11(12):2699-701. doi: 10.1021/ol9008188.

PMID:
19514797
46.

Rimonabant ameliorates insulin resistance via both adiponectin-dependent and adiponectin-independent pathways.

Watanabe T, Kubota N, Ohsugi M, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Tokuyama K, Moroi M, Sugi K, Yamauchi T, Noda T, Nagai R, Terauchi Y, Tobe K, Ueki K, Kadowaki T.

J Biol Chem. 2009 Jan 16;284(3):1803-12. doi: 10.1074/jbc.M807120200. Epub 2008 Nov 13.

47.

Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance.

Takamoto I, Terauchi Y, Kubota N, Ohsugi M, Ueki K, Kadowaki T.

Diabetes Obes Metab. 2008 Nov;10 Suppl 4:147-56. doi: 10.1111/j.1463-1326.2008.00951.x.

PMID:
18834442
48.

An Efficient reproductive method for Irs2-/- mice with C57BL/6JJcl genetic background.

Hashimoto H, Eto T, Kamisako T, Hoya N, Hatakeyama T, Arai T, Yokosuka M, Ohnishi Y, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Yamauchi T, Kubota N, Tobe K, Kadowaki T, Tamaoki N, Nomura T, Kosaka K.

Exp Anim. 2008 Jul;57(4):407-11.

49.

Fulminant type 1 diabetes mellitus observed in insulin receptor substrate 2 deficient mice.

Arai T, Hashimoto H, Kawai K, Mori A, Ohnishi Y, Hioki K, Ito M, Saito M, Ueyama Y, Ohsugi M, Suzuki R, Kubota N, Yamauchi T, Tobe K, Kadowaki T, Kosaka K.

Clin Exp Med. 2008 Jun;8(2):93-9. doi: 10.1007/s10238-008-0163-1. Epub 2008 Jul 11.

PMID:
18618219
50.

Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding.

Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Nagai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T.

Cell Metab. 2008 Jul;8(1):49-64. doi: 10.1016/j.cmet.2008.05.007.

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