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Items: 1 to 50 of 103

1.

The anti-sigma factor MucA of Pseudomonas aeruginosa: Dramatic differences of a mucA22 vs. a ΔmucA mutant in anaerobic acidified nitrite sensitivity of planktonic and biofilm bacteria in vitro and during chronic murine lung infection.

Panmanee W, Su S, Schurr MJ, Lau GW, Zhu X, Ren Z, McDaniel CT, Lu LJ, Ohman DE, Muruve DA, Panos RJ, Yu HD, Thompson TB, Tseng BS, Hassett DJ.

PLoS One. 2019 Jun 3;14(6):e0216401. doi: 10.1371/journal.pone.0216401. eCollection 2019.

2.

Surface Characterization, Antimicrobial Effectiveness, and Human Cell Response for a Biomedical Grade Polyurethane Blended with a Mixed Soft Block PTMO-Quat/PEG Copolyoxetane Polyurethane.

Wang C, Zolotarskaya O, Ashraf KM, Wen X, Ohman DE, Wynne KJ.

ACS Appl Mater Interfaces. 2019 Jun 12;11(23):20699-20714. doi: 10.1021/acsami.9b04697. Epub 2019 Jun 3.

PMID:
31117452
3.

A Polycation Antimicrobial Peptide Mimic without Resistance Buildup against Propionibacterium Acnes.

Nair SS, Zolotarskaya OY, Beckwith MJ, Ohman DE, Wynne KJ.

Macromol Biosci. 2017 Sep;17(9). doi: 10.1002/mabi.201700090. Epub 2017 Jun 12.

PMID:
28605136
4.

Real-Time Observation of Antimicrobial Polycation Effects on Escherichia coli: Adapting the Carpet Model for Membrane Disruption to Quaternary Copolyoxetanes.

Wang C, Zolotarskaya OY, Nair SS, Ehrhardt CJ, Ohman DE, Wynne KJ, Yadavalli VK.

Langmuir. 2016 Mar 29;32(12):2975-84. doi: 10.1021/acs.langmuir.5b04247. Epub 2016 Mar 21.

PMID:
26948099
5.

Dimeric c-di-GMP is required for post-translational regulation of alginate production in Pseudomonas aeruginosa.

Whitney JC, Whitfield GB, Marmont LS, Yip P, Neculai AM, Lobsanov YD, Robinson H, Ohman DE, Howell PL.

J Biol Chem. 2015 May 15;290(20):12451-62. doi: 10.1074/jbc.M115.645051. Epub 2015 Mar 27.

6.

Complete Genome Sequence of Pseudomonas aeruginosa Mucoid Strain FRD1, Isolated from a Cystic Fibrosis Patient.

Silo-Suh LA, Suh SJ, Ohman DE, Wozniak DJ, Pridgeon JW.

Genome Announc. 2015 Mar 19;3(2). pii: e00153-15. doi: 10.1128/genomeA.00153-15.

7.

Cell wall stress activates expression of a novel stress response facilitator (SrfA) under σ22 (AlgT/U) control in Pseudomonas aeruginosa.

Wood LF, Ohman DE.

Microbiology. 2015 Jan;161(Pt 1):30-40. doi: 10.1099/mic.0.081182-0. Epub 2014 Oct 21.

8.

P. aeruginosa SGNH hydrolase-like proteins AlgJ and AlgX have similar topology but separate and distinct roles in alginate acetylation.

Baker P, Ricer T, Moynihan PJ, Kitova EN, Walvoort MT, Little DJ, Whitney JC, Dawson K, Weadge JT, Robinson H, Ohman DE, Codée JD, Klassen JS, Clarke AJ, Howell PL.

PLoS Pathog. 2014 Aug 28;10(8):e1004334. doi: 10.1371/journal.ppat.1004334. eCollection 2014 Aug.

9.

High antimicrobial effectiveness with low hemolytic and cytotoxic activity for PEG/quaternary copolyoxetanes.

King A, Chakrabarty S, Zhang W, Zeng X, Ohman DE, Wood LF, Abraham S, Rao R, Wynne KJ.

Biomacromolecules. 2014 Feb 10;15(2):456-67. doi: 10.1021/bm401794p. Epub 2014 Jan 22.

10.

Structural and functional characterization of Pseudomonas aeruginosa AlgX: role of AlgX in alginate acetylation.

Riley LM, Weadge JT, Baker P, Robinson H, Codée JD, Tipton PA, Ohman DE, Howell PL.

J Biol Chem. 2013 Aug 2;288(31):22299-314. doi: 10.1074/jbc.M113.484931. Epub 2013 Jun 18.

11.

Evidence for two promoters internal to the alginate biosynthesis operon in Pseudomonas aeruginosa.

Paletta JL, Ohman DE.

Curr Microbiol. 2012 Dec;65(6):770-5. doi: 10.1007/s00284-012-0228-y. Epub 2012 Sep 18.

PMID:
22986819
12.
13.

A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and algT/U activity results in the loss of alginate production.

Sautter R, Ramos D, Schneper L, Ciofu O, Wassermann T, Koh CL, Heydorn A, Hentzer M, Høiby N, Kharazmi A, Molin S, Devries CA, Ohman DE, Mathee K.

Gene. 2012 May 1;498(2):242-53. doi: 10.1016/j.gene.2011.11.005. Epub 2011 Nov 9.

14.

Pseudomonas aeruginosa elastase provides an escape from phagocytosis by degrading the pulmonary surfactant protein-A.

Kuang Z, Hao Y, Walling BE, Jeffries JL, Ohman DE, Lau GW.

PLoS One. 2011;6(11):e27091. doi: 10.1371/journal.pone.0027091. Epub 2011 Nov 1.

15.

Staphylolysin is an effective therapeutic agent for Staphylococcus aureus experimental keratitis.

Barequet IS, Bourla N, Pessach YN, Safrin M, Yankovich D, Ohman DE, Rosner M, Kessler E.

Graefes Arch Clin Exp Ophthalmol. 2012 Feb;250(2):223-9. doi: 10.1007/s00417-011-1822-6. Epub 2011 Sep 24.

PMID:
21947265
16.

Structural basis for alginate secretion across the bacterial outer membrane.

Whitney JC, Hay ID, Li C, Eckford PD, Robinson H, Amaya MF, Wood LF, Ohman DE, Bear CE, Rehm BH, Howell PL.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13083-8. doi: 10.1073/pnas.1104984108. Epub 2011 Jul 21.

17.

Highly effective, water-soluble, hemocompatible 1,3-propylene oxide-based antimicrobials: poly[(3,3-quaternary/PEG)-copolyoxetanes].

Chakrabarty S, King A, Kurt P, Zhang W, Ohman DE, Wood LF, Lovelace C, Rao R, Wynne KJ.

Biomacromolecules. 2011 Mar 14;12(3):757-69. doi: 10.1021/bm101381y. Epub 2011 Jan 31.

PMID:
21280645
18.

AlgK is a TPR-containing protein and the periplasmic component of a novel exopolysaccharide secretin.

Keiski CL, Harwich M, Jain S, Neculai AM, Yip P, Robinson H, Whitney JC, Riley L, Burrows LL, Ohman DE, Howell PL.

Structure. 2010 Feb 10;18(2):265-73. doi: 10.1016/j.str.2009.11.015.

19.

Isolation, characterization, and utilization of a temperature-sensitive allele of a Pseudomonas replicon.

Silo-Suh LA, Elmore B, Ohman DE, Suh SJ.

J Microbiol Methods. 2009 Sep;78(3):319-24. doi: 10.1016/j.mimet.2009.07.002. Epub 2009 Jul 15.

20.

Bio-inspired chemical reactors for growing aligned gold nanoparticle-like wires.

Lu ZX, Wood LF, Ohman DE, Collinson MM.

Chem Commun (Camb). 2009 Jul 28;(28):4200-2. doi: 10.1039/b906250e. Epub 2009 Jun 12.

PMID:
19585020
21.

Expression, refolding, crystallization and preliminary X-ray analysis of Pseudomonas aeruginosa AlgE.

Whitney JC, Neculai AM, Ohman DE, Howell PL.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 May 1;65(Pt 5):463-6. doi: 10.1107/S174430910901094X. Epub 2009 Apr 24.

22.

Evaluation of Pseudomonas aeruginosa staphylolysin (LasA protease) in the treatment of methicillin-resistant Staphylococcus aureus endophthalmitis in a rat model.

Barequet IS, Habot-Wilner Z, Mann O, Safrin M, Ohman DE, Kessler E, Rosner M.

Graefes Arch Clin Exp Ophthalmol. 2009 Jul;247(7):913-7. doi: 10.1007/s00417-009-1061-2. Epub 2009 Mar 12.

PMID:
19280208
23.

Use of cell wall stress to characterize sigma 22 (AlgT/U) activation by regulated proteolysis and its regulon in Pseudomonas aeruginosa.

Wood LF, Ohman DE.

Mol Microbiol. 2009 Apr;72(1):183-201. doi: 10.1111/j.1365-2958.2009.06635.x. Epub 2009 Feb 17.

24.

Membrane topology and roles of Pseudomonas aeruginosa Alg8 and Alg44 in alginate polymerization.

Oglesby LL, Jain S, Ohman DE.

Microbiology. 2008 Jun;154(Pt 6):1605-15. doi: 10.1099/mic.0.2007/015305-0.

25.

The NtrC family regulator AlgB, which controls alginate biosynthesis in mucoid Pseudomonas aeruginosa, binds directly to the algD promoter.

Leech AJ, Sprinkle A, Wood L, Wozniak DJ, Ohman DE.

J Bacteriol. 2008 Jan;190(2):581-9. Epub 2007 Nov 2.

26.

Highly effective contact antimicrobial surfaces via polymer surface modifiers.

Kurt P, Wood L, Ohman DE, Wynne KJ.

Langmuir. 2007 Apr 24;23(9):4719-23. Epub 2007 Mar 28.

PMID:
17388618
27.
31.

Polyurethane biocidal polymeric surface modifiers.

Makal U, Wood L, Ohman DE, Wynne KJ.

Biomaterials. 2006 Mar;27(8):1316-26. Epub 2005 Sep 21.

PMID:
16181672
32.
33.

Epimerase active domain of Pseudomonas aeruginosa AlgG, a protein that contains a right-handed beta-helix.

Douthit SA, Dlakic M, Ohman DE, Franklin MJ.

J Bacteriol. 2005 Jul;187(13):4573-83.

34.

Degradation and synthesis kinetics of quorum-sensing autoinducer in Pseudomonas aeruginosa cultivation.

Chen CC, Riadi L, Suh SJ, Ohman DE, Ju LK.

J Biotechnol. 2005 Apr 20;117(1):1-10.

PMID:
15831242
35.
36.

Development of tools for the genetic manipulation of Pseudomonas aeruginosa.

Suh SJ, Silo-Suh LA, Ohman DE.

J Microbiol Methods. 2004 Aug;58(2):203-12.

PMID:
15234518
37.

Alginate production affects Pseudomonas aeruginosa biofilm development and architecture, but is not essential for biofilm formation.

Stapper AP, Narasimhan G, Ohman DE, Barakat J, Hentzer M, Molin S, Kharazmi A, Høiby N, Mathee K.

J Med Microbiol. 2004 Jul;53(Pt 7):679-90.

PMID:
15184541
38.
39.

Pseudomonas aeruginosa LasA protease in treatment of experimental staphylococcal keratitis.

Barequet IS, Ben Simon GJ, Safrin M, Ohman DE, Kessler E.

Antimicrob Agents Chemother. 2004 May;48(5):1681-7.

40.

Comparative analysis of plant and animal models for characterization of Burkholderia cepacia virulence.

Bernier SP, Silo-Suh L, Woods DE, Ohman DE, Sokol PA.

Infect Immun. 2003 Sep;71(9):5306-13.

41.

The Pseudomonas fluorescens AlgG protein, but not its mannuronan C-5-epimerase activity, is needed for alginate polymer formation.

Gimmestad M, Sletta H, Ertesvåg H, Bakkevig K, Jain S, Suh SJ, Skjåk-Braek G, Ellingsen TE, Ohman DE, Valla S.

J Bacteriol. 2003 Jun;185(12):3515-23.

42.

The dual roles of AlgG in C-5-epimerization and secretion of alginate polymers in Pseudomonas aeruginosa.

Jain S, Franklin MJ, Ertesvåg H, Valla S, Ohman DE.

Mol Microbiol. 2003 Feb;47(4):1123-33.

43.
45.

Characterization of algG encoding C5-epimerase in the alginate biosynthetic gene cluster of Pseudomonas fluorescens.

Morea A, Mathee K, Franklin MJ, Giacomini A, O'Regan M, Ohman DE.

Gene. 2001 Oct 31;278(1-2):107-14.

PMID:
11707327
46.

A secreted aminopeptidase of Pseudomonas aeruginosa. Identification, primary structure, and relationship to other aminopeptidases.

Cahan R, Axelrad I, Safrin M, Ohman DE, Kessler E.

J Biol Chem. 2001 Nov 23;276(47):43645-52. Epub 2001 Aug 31.

47.

Role of alginate and its O acetylation in formation of Pseudomonas aeruginosa microcolonies and biofilms.

Nivens DE, Ohman DE, Williams J, Franklin MJ.

J Bacteriol. 2001 Feb;183(3):1047-57.

48.

Role of alginate O acetylation in resistance of mucoid Pseudomonas aeruginosa to opsonic phagocytosis.

Pier GB, Coleman F, Grout M, Franklin M, Ohman DE.

Infect Immun. 2001 Mar;69(3):1895-901.

50.

Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.

Mathee K, Ciofu O, Sternberg C, Lindum PW, Campbell JI, Jensen P, Johnsen AH, Givskov M, Ohman DE, Molin S, Høiby N, Kharazmi A.

Microbiology. 1999 Jun;145 ( Pt 6):1349-57.

PMID:
10411261

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