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Items: 9


Loss of MAP3K7 Sensitizes Prostate Cancer Cells to CDK1/2 Inhibition and DNA Damage by Disrupting Homologous Recombination.

Washino S, Rider LC, Romero L, Jillson LK, Affandi T, Ohm AM, Lam ET, Reyland ME, Costello JC, Cramer SD.

Mol Cancer Res. 2019 Oct;17(10):1985-1998. doi: 10.1158/1541-7786.MCR-18-1335. Epub 2019 Jul 12.


EGF receptor and PKCδ kinase activate DNA damage-induced pro-survival and pro-apoptotic signaling via biphasic activation of ERK and MSK1 kinases.

Ohm AM, Affandi T, Reyland ME.

J Biol Chem. 2019 Mar 22;294(12):4488-4497. doi: 10.1074/jbc.RA118.006944. Epub 2019 Jan 24.


Co-dependency of PKCδ and K-Ras: inverse association with cytotoxic drug sensitivity in KRAS mutant lung cancer.

Ohm AM, Tan AC, Heasley LE, Reyland ME.

Oncogene. 2017 Jul 27;36(30):4370-4378. doi: 10.1038/onc.2017.27. Epub 2017 Apr 3.


PKCδ regulates integrin αVβ3 expression and transformed growth of K-ras dependent lung cancer cells.

Symonds JM, Ohm AM, Tan AC, Reyland ME.

Oncotarget. 2016 Apr 5;7(14):17905-19. doi: 10.18632/oncotarget.7560.


Protein kinase Cδ is required for ErbB2-driven mammary gland tumorigenesis and negatively correlates with prognosis in human breast cancer.

Allen-Petersen BL, Carter CJ, Ohm AM, Reyland ME.

Oncogene. 2014 Mar 6;33(10):1306-15. doi: 10.1038/onc.2013.59. Epub 2013 Mar 11.


Regulated binding of importin-α to protein kinase Cδ in response to apoptotic signals facilitates nuclear import.

Adwan TS, Ohm AM, Jones DN, Humphries MJ, Reyland ME.

J Biol Chem. 2011 Oct 14;286(41):35716-24. doi: 10.1074/jbc.M111.255950. Epub 2011 Aug 24.


Protein kinase C δ is a downstream effector of oncogenic K-ras in lung tumors.

Symonds JM, Ohm AM, Carter CJ, Heasley LE, Boyle TA, Franklin WA, Reyland ME.

Cancer Res. 2011 Mar 15;71(6):2087-97. doi: 10.1158/0008-5472.CAN-10-1511. Epub 2011 Feb 18.


Tyrosine phosphorylation regulates nuclear translocation of PKCdelta.

Humphries MJ, Ohm AM, Schaack J, Adwan TS, Reyland ME.

Oncogene. 2008 May 8;27(21):3045-53. Epub 2007 Dec 3.


Induction of apoptosis is driven by nuclear retention of protein kinase C delta.

DeVries-Seimon TA, Ohm AM, Humphries MJ, Reyland ME.

J Biol Chem. 2007 Aug 3;282(31):22307-14. Epub 2007 Jun 11.

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