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Items: 1 to 50 of 78

1.

Lack of Fractalkine Receptor on Macrophages Impairs Spontaneous Recovery of Ribbon Synapses After Moderate Noise Trauma in C57BL/6 Mice.

Kaur T, Clayman AC, Nash AJ, Schrader AD, Warchol ME, Ohlemiller KK.

Front Neurosci. 2019 Jun 13;13:620. doi: 10.3389/fnins.2019.00620. eCollection 2019.

2.

Vesicular Glutamatergic Transmission in Noise-Induced Loss and Repair of Cochlear Ribbon Synapses.

Kim KX, Payne S, Yang-Hood A, Li SZ, Davis B, Carlquist J, V-Ghaffari B, Gantz JA, Kallogjeri D, Fitzpatrick JAJ, Ohlemiller KK, Hirose K, Rutherford MA.

J Neurosci. 2019 Jun 5;39(23):4434-4447. doi: 10.1523/JNEUROSCI.2228-18.2019. Epub 2019 Mar 29.

PMID:
30926748
3.

The endocochlear potential as an indicator of reticular lamina integrity after noise exposure in mice.

Ohlemiller KK, Kaur T, Warchol ME, Withnell RH.

Hear Res. 2018 Apr;361:138-151. doi: 10.1016/j.heares.2018.01.015. Epub 2018 Feb 1.

4.

Genetic disruption of fractalkine signaling leads to enhanced loss of cochlear afferents following ototoxic or acoustic injury.

Kaur T, Ohlemiller KK, Warchol ME.

J Comp Neurol. 2018 Apr 1;526(5):824-835. doi: 10.1002/cne.24369. Epub 2017 Dec 17.

5.

Generation and Characterization of α9 and α10 Nicotinic Acetylcholine Receptor Subunit Knockout Mice on a C57BL/6J Background.

Morley BJ, Dolan DF, Ohlemiller KK, Simmons DD.

Front Neurosci. 2017 Sep 21;11:516. doi: 10.3389/fnins.2017.00516. eCollection 2017.

6.

Hearing loss without overt metabolic acidosis in ATP6V1B1 deficient MRL mice, a new genetic model for non-syndromic deafness with enlarged vestibular aqueducts.

Tian C, Gagnon LH, Longo-Guess C, Korstanje R, Sheehan SM, Ohlemiller KK, Schrader AD, Lett JM, Johnson KR.

Hum Mol Genet. 2017 Oct 1;26(19):3722-3735. doi: 10.1093/hmg/ddx257.

7.

Application of Mouse Models to Research in Hearing and Balance.

Ohlemiller KK, Jones SM, Johnson KR.

J Assoc Res Otolaryngol. 2016 Dec;17(6):493-523. Epub 2016 Oct 17. Review.

8.

QTL Mapping of Endocochlear Potential Differences between C57BL/6J and BALB/cJ mice.

Ohlemiller KK, Kiener AL, Gagnon PM.

J Assoc Res Otolaryngol. 2016 Jun;17(3):173-94. doi: 10.1007/s10162-016-0558-8. Epub 2016 Mar 15.

9.

Oncomodulin, an EF-Hand Ca2+ Buffer, Is Critical for Maintaining Cochlear Function in Mice.

Tong B, Hornak AJ, Maison SF, Ohlemiller KK, Liberman MC, Simmons DD.

J Neurosci. 2016 Feb 3;36(5):1631-5. doi: 10.1523/JNEUROSCI.3311-15.2016.

10.

Progressive Hearing Loss in Mice Carrying a Mutation in Usp53.

Kazmierczak M, Harris SL, Kazmierczak P, Shah P, Starovoytov V, Ohlemiller KK, Schwander M.

J Neurosci. 2015 Nov 25;35(47):15582-98. doi: 10.1523/JNEUROSCI.1965-15.2015.

11.

Fractalkine Signaling Regulates Macrophage Recruitment into the Cochlea and Promotes the Survival of Spiral Ganglion Neurons after Selective Hair Cell Lesion.

Kaur T, Zamani D, Tong L, Rubel EW, Ohlemiller KK, Hirose K, Warchol ME.

J Neurosci. 2015 Nov 11;35(45):15050-61. doi: 10.1523/JNEUROSCI.2325-15.2015.

12.

Systemic lipopolysaccharide induces cochlear inflammation and exacerbates the synergistic ototoxicity of kanamycin and furosemide.

Hirose K, Li SZ, Ohlemiller KK, Ransohoff RM.

J Assoc Res Otolaryngol. 2014 Aug;15(4):555-70. doi: 10.1007/s10162-014-0458-8. Epub 2014 May 21.

13.

Prophylactic and therapeutic functions of drug combinations against noise-induced hearing loss.

Bao J, Hungerford M, Luxmore R, Ding D, Qiu Z, Lei D, Yang A, Liang R, Ohlemiller KK.

Hear Res. 2013 Oct;304:33-40. doi: 10.1016/j.heares.2013.06.004. Epub 2013 Jun 18.

14.

Disease correction by combined neonatal intracranial AAV and systemic lentiviral gene therapy in Sanfilippo Syndrome type B mice.

Heldermon CD, Qin EY, Ohlemiller KK, Herzog ED, Brown JR, Vogler C, Hou W, Orrock JL, Crawford BE, Sands MS.

Gene Ther. 2013 Sep;20(9):913-21. doi: 10.1038/gt.2013.14. Epub 2013 Mar 28.

15.

Retroviral-vector-mediated gene therapy to mucopolysaccharidosis I mice improves sensorimotor impairments and other behavioral deficits.

Baldo G, Wozniak DF, Ohlemiller KK, Zhang Y, Giugliani R, Ponder KP.

J Inherit Metab Dis. 2013 May;36(3):499-512. doi: 10.1007/s10545-012-9530-x. Epub 2012 Sep 15.

16.

Comment on Folic acid improves inner ear vascularization in hyperhomocysteinemic mice, Hearing Research 2012, 284: 42-51 (Kundu, Munjal, N. Tyagi, Sen, A. Tyagi, S. Tyagi).

Ohlemiller KK.

Hear Res. 2012 Dec;294(1-2):166-7; author reply 168-70. doi: 10.1016/j.heares.2012.04.023. Epub 2012 May 15. No abstract available.

PMID:
22634391
17.

Inheritance patterns of noise vulnerability and "protectability" in (C57BL/6J × CBA/J) F1 hybrid mice.

Barden EK, Rellinger EA, Ortmann AJ, Ohlemiller KK.

J Am Acad Audiol. 2012 May;23(5):332-40. doi: 10.3766/jaaa.23.5.4.

PMID:
22533976
18.

Conditional deletion of calcium-modulating cyclophilin ligand causes deafness in mice.

Bryda EC, Johnson NT, Ohlemiller KK, Besch-Williford CL, Moore E, Bram RJ.

Mamm Genome. 2012 Apr;23(3-4):270-6. doi: 10.1007/s00335-011-9381-z. Epub 2011 Dec 15.

PMID:
22170629
19.

Nutrient-enhanced diet reduces noise-induced damage to the inner ear and hearing loss.

Le Prell CG, Gagnon PM, Bennett DC, Ohlemiller KK.

Transl Res. 2011 Jul;158(1):38-53. doi: 10.1016/j.trsl.2011.02.006. Epub 2011 Mar 21.

20.

Protection by low-dose kanamycin against noise-induced hearing loss in mice: dependence on dosing regimen and genetic background.

Ohlemiller KK, Rybak Rice ME, Rosen AD, Montgomery SC, Gagnon PM.

Hear Res. 2011 Oct;280(1-2):141-7. doi: 10.1016/j.heares.2011.05.007. Epub 2011 May 27.

21.

Anti-epileptic drugs delay age-related loss of spiral ganglion neurons via T-type calcium channel.

Lei D, Gao X, Perez P, Ohlemiller KK, Chen CC, Campbell KP, Hood AY, Bao J.

Hear Res. 2011 Aug;278(1-2):106-12. doi: 10.1016/j.heares.2011.05.010. Epub 2011 May 26.

22.

Old mice lacking high-affinity nicotine receptors resist acoustic trauma.

Shen H, Lin Z, Lei D, Han J, Ohlemiller KK, Bao J.

Hear Res. 2011 Jul;277(1-2):184-91. doi: 10.1016/j.heares.2011.01.009. Epub 2011 Jan 25.

23.

Divergence of noise vulnerability in cochleae of young CBA/J and CBA/CaJ mice.

Ohlemiller KK, Rybak Rice ME, Rellinger EA, Ortmann AJ.

Hear Res. 2011 Feb;272(1-2):13-20. doi: 10.1016/j.heares.2010.11.006. Epub 2010 Nov 23.

24.

Different cellular and genetic basis of noise-related endocochlear potential reduction in CBA/J and BALB/cJ mice.

Ohlemiller KK, Rosen AD, Rellinger EA, Montgomery SC, Gagnon PM.

J Assoc Res Otolaryngol. 2011 Feb;12(1):45-58. doi: 10.1007/s10162-010-0238-z. Epub 2010 Oct 5.

25.

Divergent aging characteristics in CBA/J and CBA/CaJ mouse cochleae.

Ohlemiller KK, Dahl AR, Gagnon PM.

J Assoc Res Otolaryngol. 2010 Dec;11(4):605-23. doi: 10.1007/s10162-010-0228-1. Epub 2010 Aug 13.

26.

No dramatic age-related loss of hair cells and spiral ganglion neurons in Bcl-2 over-expression mice or Bax null mice.

Shen H, Matsui JI, Lei D, Han L, Ohlemiller KK, Bao J.

Mol Neurodegener. 2010 Jul 16;5:28. doi: 10.1186/1750-1326-5-28.

27.

Age-related neuronal loss in the cochlea is not delayed by synaptic modulation.

Jin D, Ohlemiller KK, Lei D, Dong E, Role L, Ryugo DK, Bao J.

Neurobiol Aging. 2011 Dec;32(12):2321.e13-23. doi: 10.1016/j.neurobiolaging.2010.05.011. Epub 2010 Jun 26.

28.

Therapeutic efficacy of bone marrow transplant, intracranial AAV-mediated gene therapy, or both in the mouse model of MPS IIIB.

Heldermon CD, Ohlemiller KK, Herzog ED, Vogler C, Qin E, Wozniak DF, Tan Y, Orrock JL, Sands MS.

Mol Ther. 2010 May;18(5):873-80. doi: 10.1038/mt.2010.17. Epub 2010 Feb 23.

29.

Protection against noise-induced hearing loss in young CBA/J mice by low-dose kanamycin.

Fernandez EA, Ohlemiller KK, Gagnon PM, Clark WW.

J Assoc Res Otolaryngol. 2010 Jun;11(2):235-44. doi: 10.1007/s10162-009-0204-9. Epub 2010 Jan 22.

30.

A major effect QTL on chromosome 18 for noise injury to the mouse cochlear lateral wall.

Ohlemiller KK, Rosen AD, Gagnon PM.

Hear Res. 2010 Feb;260(1-2):47-53. doi: 10.1016/j.heares.2009.11.006. Epub 2009 Nov 12.

31.

Age-related loss of spiral ganglion neurons.

Bao J, Ohlemiller KK.

Hear Res. 2010 Jun 1;264(1-2):93-7. doi: 10.1016/j.heares.2009.10.009. Epub 2009 Oct 23. Review.

32.

A self-inactivating gamma-retroviral vector reduces manifestations of mucopolysaccharidosis I in mice.

Metcalf JA, Ma X, Linders B, Wu S, Schambach A, Ohlemiller KK, Kovacs A, Bigg M, He L, Tollefsen DM, Ponder KP.

Mol Ther. 2010 Feb;18(2):334-42. doi: 10.1038/mt.2009.236. Epub 2009 Oct 20.

33.

Metabolic adaptations to interrupted glycosaminoglycan recycling.

Woloszynek JC, Kovacs A, Ohlemiller KK, Roberts M, Sands MS.

J Biol Chem. 2009 Oct 23;284(43):29684-91. doi: 10.1074/jbc.M109.020818. Epub 2009 Aug 21.

34.

Mechanisms and genes in human strial presbycusis from animal models.

Ohlemiller KK.

Brain Res. 2009 Jun 24;1277:70-83. doi: 10.1016/j.brainres.2009.02.079. Epub 2009 Mar 12. Review.

35.

Absence of strial melanin coincides with age-associated marginal cell loss and endocochlear potential decline.

Ohlemiller KK, Rice ME, Lett JM, Gagnon PM.

Hear Res. 2009 Mar;249(1-2):1-14. doi: 10.1016/j.heares.2008.12.005. Epub 2008 Dec 25.

PMID:
19141317
36.

Recent findings and emerging questions in cochlear noise injury.

Ohlemiller KK.

Hear Res. 2008 Nov;245(1-2):5-17. doi: 10.1016/j.heares.2008.08.007. Epub 2008 Aug 29. Review. No abstract available.

37.

Strial microvascular pathology and age-associated endocochlear potential decline in NOD congenic mice.

Ohlemiller KK, Rice ME, Gagnon PM.

Hear Res. 2008 Oct;244(1-2):85-97. doi: 10.1016/j.heares.2008.08.001. Epub 2008 Aug 12.

38.

Improved retroviral vector design results in sustained expression after adult gene therapy in mucopolysaccharidosis I mice.

Herati RS, Ma X, Tittiger M, Ohlemiller KK, Kovacs A, Ponder KP.

J Gene Med. 2008 Sep;10(9):972-82. doi: 10.1002/jgm.1229.

39.

Lentiviral-transduced human mesenchymal stem cells persistently express therapeutic levels of enzyme in a xenotransplantation model of human disease.

Meyerrose TE, Roberts M, Ohlemiller KK, Vogler CA, Wirthlin L, Nolta JA, Sands MS.

Stem Cells. 2008 Jul;26(7):1713-22. doi: 10.1634/stemcells.2008-0008. Epub 2008 Apr 24.

40.

Development of sensory, motor and behavioral deficits in the murine model of Sanfilippo syndrome type B.

Heldermon CD, Hennig AK, Ohlemiller KK, Ogilvie JM, Herzog ED, Breidenbach A, Vogler C, Wozniak DF, Sands MS.

PLoS One. 2007 Aug 22;2(8):e772.

41.

Carbonic anhydrase XIV deficiency produces a functional defect in the retinal light response.

Ogilvie JM, Ohlemiller KK, Shah GN, Ulmasov B, Becker TA, Waheed A, Hennig AK, Lukasiewicz PD, Sly WS.

Proc Natl Acad Sci U S A. 2007 May 15;104(20):8514-9. Epub 2007 May 7.

42.

Prophylactic and therapeutic functions of T-type calcium blockers against noise-induced hearing loss.

Shen H, Zhang B, Shin JH, Lei D, Du Y, Gao X, Wang Q, Ohlemiller KK, Piccirillo J, Bao J.

Hear Res. 2007 Apr;226(1-2):52-60. Epub 2006 Dec 31.

43.

Genetic dependence of cochlear cells and structures injured by noise.

Ohlemiller KK, Gagnon PM.

Hear Res. 2007 Feb;224(1-2):34-50. Epub 2006 Dec 18.

44.

Temporal and genetic influences on protection against noise-induced hearing loss by hypoxic preconditioning in mice.

Gagnon PM, Simmons DD, Bao J, Lei D, Ortmann AJ, Ohlemiller KK.

Hear Res. 2007 Apr;226(1-2):79-91. Epub 2006 Nov 14.

PMID:
17107766
45.

Cellular correlates of age-related endocochlear potential reduction in a mouse model.

Ohlemiller KK, Lett JM, Gagnon PM.

Hear Res. 2006 Oct;220(1-2):10-26. Epub 2006 Aug 9.

PMID:
16901664
46.

Contributions of mouse models to understanding of age- and noise-related hearing loss.

Ohlemiller KK.

Brain Res. 2006 May 26;1091(1):89-102. Epub 2006 May 2. Review.

PMID:
16631134
47.

Cerebellar synaptic defects and abnormal motor behavior in mice lacking alpha- and beta-dystrobrevin.

Grady RM, Wozniak DF, Ohlemiller KK, Sanes JR.

J Neurosci. 2006 Mar 15;26(11):2841-51.

48.

Constitutive nitric oxide synthase activity is required to trigger ischemic tolerance in mouse retina.

Zhu Y, Ohlemiller KK, McMahan BK, Park TS, Gidday JM.

Exp Eye Res. 2006 Jan;82(1):153-63. Epub 2005 Jul 20.

PMID:
16045907
49.

Requirement of nicotinic acetylcholine receptor subunit beta2 in the maintenance of spiral ganglion neurons during aging.

Bao J, Lei D, Du Y, Ohlemiller KK, Beaudet AL, Role LW.

J Neurosci. 2005 Mar 23;25(12):3041-5. Erratum in: J Neurosci. 2005 Jun 29;25(26):2 p following 6262.

50.

Activity-dependent transcription regulation of PSD-95 by neuregulin-1 and Eos.

Bao J, Lin H, Ouyang Y, Lei D, Osman A, Kim TW, Mei L, Dai P, Ohlemiller KK, Ambron RT.

Nat Neurosci. 2004 Nov;7(11):1250-8. Epub 2004 Oct 24.

PMID:
15494726

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