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Items: 1 to 50 of 60

1.

Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV.

Marshall VA, Labo N, Hao XP, Holdridge B, Thompson M, Miley W, Brands C, Coalter V, Kiser R, Anver M, Golubeva Y, Warner A, Jaffe ES, Piatak M Jr, Wong SW, Ohlen C, MacAllister R, Smedley J, Deleage C, Del Prete GQ, Lifson JD, Estes JD, Whitby D.

PLoS Pathog. 2018 Jul 12;14(7):e1007130. doi: 10.1371/journal.ppat.1007130. eCollection 2018 Jul.

2.

Correction: Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8+ T Cells Conveys the Ability to Suppress SIV Replication.

Barsov EV, Trivett MT, Minang JT, Sun H, Ohlen C, Ott DE.

PLoS One. 2018 Mar 28;13(3):e0195246. doi: 10.1371/journal.pone.0195246. eCollection 2018.

3.

T-cell responses to KSHV infection: a systematic approach.

Roshan R, Labo N, Trivett M, Miley W, Marshall V, Coren L, Cornejo Castro EM, Perez H, Holdridge B, Davis E, Matus-Nicodemos R, Ayala VI, Sowder R 2nd, Wyvill KM, Aleman K, Fennessey C, Lifson J, Polizzotto MN, Douek D, Keele B, Uldrick TS, Yarchoan R, Ohlen C, Ott D, Whitby D.

Oncotarget. 2017 Nov 25;8(65):109402-109416. doi: 10.18632/oncotarget.22683. eCollection 2017 Dec 12.

4.

Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy.

Fennessey CM, Pinkevych M, Immonen TT, Reynaldi A, Venturi V, Nadella P, Reid C, Newman L, Lipkey L, Oswald K, Bosche WJ, Trivett MT, Ohlen C, Ott DE, Estes JD, Del Prete GQ, Lifson JD, Davenport MP, Keele BF.

PLoS Pathog. 2017 May 4;13(5):e1006359. doi: 10.1371/journal.ppat.1006359. eCollection 2017 May.

5.

Adoptive Transfer of Engineered Rhesus Simian Immunodeficiency Virus-Specific CD8+ T Cells Reduces the Number of Transmitted/Founder Viruses Established in Rhesus Macaques.

Ayala VI, Trivett MT, Barsov EV, Jain S, Piatak M Jr, Trubey CM, Alvord WG, Chertova E, Roser JD, Smedley J, Komin A, Keele BF, Ohlen C, Ott DE.

J Virol. 2016 Oct 14;90(21):9942-9952. doi: 10.1128/JVI.01522-16. Print 2016 Nov 1.

6.

A novel SIV gag-specific CD4(+)T-cell clone suppresses SIVmac239 replication in CD4(+)T cells revealing the interplay between antiviral effector cells and their infected targets.

Ayala VI, Trivett MT, Coren LV, Jain S, Bohn PS, Wiseman RW, O'Connor DH, Ohlen C, Ott DE.

Virology. 2016 Jun;493:100-12. doi: 10.1016/j.virol.2016.03.013. Epub 2016 Mar 25.

7.

Potent restriction of HIV-1 and SIVmac239 replication by African green monkey TRIM5α.

Coren LV, Trivett MT, Jain S, Ayala VI, Del Prete GQ, Ohlen C, Ott DE.

Retrovirology. 2015 Feb 7;12:11. doi: 10.1186/s12977-015-0137-9.

8.

Production of retroviral constructs for effective transfer and expression of T-cell receptor genes using Golden Gate cloning.

Coren LV, Jain S, Trivett MT, Ohlen C, Ott DE.

Biotechniques. 2015 Mar 1;58(3):135-9. doi: 10.2144/000114265. eCollection 2015 Mar.

9.

African green monkey TRIM5α restriction in simian immunodeficiency virus-specific rhesus macaque effector CD4 T cells enhances their survival and antiviral function.

Jain S, Trivett MT, Ayala VI, Ohlen C, Ott DE.

J Virol. 2015 Apr;89(8):4449-56. doi: 10.1128/JVI.03598-14. Epub 2015 Feb 4.

10.

Src-kinase inhibitors sensitize human cells of myeloid origin to Toll-like-receptor-induced interleukin 12 synthesis.

Wölfl M, Schwinn S, Yoo YE, Reß ML, Braun M, Chopra M, Schreiber SC, Ayala VI, Ohlen C, Eyrich M, Beilhack A, Schlegel PG.

Blood. 2013 Aug 15;122(7):1203-13. doi: 10.1182/blood-2013-03-488072. Epub 2013 Jul 8.

11.

Transduction of SIV-specific TCR genes into rhesus macaque CD8+ T cells conveys the ability to suppress SIV replication.

Barsov EV, Trivett MT, Minang JT, Sun H, Ohlen C, Ott DE.

PLoS One. 2011;6(8):e23703. doi: 10.1371/journal.pone.0023703. Epub 2011 Aug 23. Erratum in: PLoS One. 2018 Mar 28;13(3):e0195246.

12.

TCR triggering transcriptionally downregulates CCR5 expression on rhesus macaque CD4(+) T-cells with no measurable effect on susceptibility to SIV infection.

Minang JT, Trivett MT, Barsov EV, Del Prete GQ, Trubey CM, Thomas JA, Gorelick RJ, Piatak M Jr, Ott DE, Ohlen C.

Virology. 2011 Jan 5;409(1):132-40. doi: 10.1016/j.virol.2010.10.005. Epub 2010 Oct 28.

13.

Long-lasting humoral and cellular immune responses and mucosal dissemination after intramuscular DNA immunization.

Patel V, Valentin A, Kulkarni V, Rosati M, Bergamaschi C, Jalah R, Alicea C, Minang JT, Trivett MT, Ohlen C, Zhao J, Robert-Guroff M, Khan AS, Draghia-Akli R, Felber BK, Pavlakis GN.

Vaccine. 2010 Jul 5;28(30):4827-36. doi: 10.1016/j.vaccine.2010.04.064. Epub 2010 May 6.

14.

In situ detection of Gag-specific CD8+ cells in the GI tract of SIV infected Rhesus macaques.

Tjernlund A, Zhu J, Laing K, Diem K, McDonald D, Vazquez J, Cao J, Ohlen C, McElrath MJ, Picker LJ, Corey L.

Retrovirology. 2010 Feb 16;7:12. doi: 10.1186/1742-4690-7-12.

15.

Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous simian immunodeficiency virus-specific CD8+ T cell clones in rhesus macaques during acute infection.

Minang JT, Trivett MT, Bolton DL, Trubey CM, Estes JD, Li Y, Smedley J, Pung R, Rosati M, Jalah R, Pavlakis GN, Felber BK, Piatak M Jr, Roederer M, Lifson JD, Ott DE, Ohlen C.

J Immunol. 2010 Jan 1;184(1):315-26. doi: 10.4049/jimmunol.0902410. Epub 2009 Nov 30.

16.

Trafficking, persistence, and activation state of adoptively transferred allogeneic and autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones during acute and chronic infection of rhesus macaques.

Bolton DL, Minang JT, Trivett MT, Song K, Tuscher JJ, Li Y, Piatak M Jr, O'Connor D, Lifson JD, Roederer M, Ohlen C.

J Immunol. 2010 Jan 1;184(1):303-14. doi: 10.4049/jimmunol.0902413. Epub 2009 Nov 30.

17.

Nef-mediated MHC class I down-regulation unmasks clonal differences in virus suppression by SIV-specific CD8(+) T cells independent of IFN-gamma and CD107a responses.

Minang JT, Trivett MT, Coren LV, Barsov EV, Piatak M Jr, Ott DE, Ohlen C.

Virology. 2009 Aug 15;391(1):130-9. doi: 10.1016/j.virol.2009.06.008. Epub 2009 Jun 24.

18.

DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire.

Rice J, Dossett ML, Ohlén C, Buchan SL, Kendall TJ, Dunn SN, Stevenson FK, Greenberg PD.

Eur J Immunol. 2008 Aug;38(8):2118-30. doi: 10.1002/eji.200838213.

19.

Peripheral CD8+ T cell tolerance to self-proteins is regulated proximally at the T cell receptor.

Teague RM, Greenberg PD, Fowler C, Huang MZ, Tan X, Morimoto J, Dossett ML, Huseby ES, Ohlén C.

Immunity. 2008 May;28(5):662-74. doi: 10.1016/j.immuni.2008.03.012.

20.

The Mamu B 17-restricted SIV Nef IW9 to TW9 mutation abrogates correct epitope processing and presentation without loss of replicative fitness.

Minang JT, Trivett MT, Coren LV, Barsov EV, Piatak M Jr, Chertov O, Chertova E, Ott DE, Ohlen C.

Virology. 2008 May 25;375(1):307-14. doi: 10.1016/j.virol.2008.02.005. Epub 2008 Mar 6.

21.

Efficient inhibition of SIV replication in rhesus CD4+ T-cell clones by autologous immortalized SIV-specific CD8+ T-cell clones.

Minang JT, Barsov EV, Yuan F, Trivett MT, Piatak M Jr, Lifson JD, Ott DE, Ohlen C.

Virology. 2008 Mar 15;372(2):430-41. Epub 2008 Feb 20.

22.

Pillars article: Association of class I major histocompatibility heavy and light chains induced by viral peptides. Nature 1989. 340: 443-448.

Townsend A, Ohlén C, Bastin J, Ljunggren HG, Foster L, Kärre K.

J Immunol. 2007 Oct 1;179(7):4301-6. No abstract available.

23.

Induction of tolerance in CD8+ T cells to a transgenic autoantigen expressed in the liver does not require cross-presentation.

Morimoto J, Tan X, Teague RM, Ohlén C, Greenberg PD.

J Immunol. 2007 Jun 1;178(11):6849-60.

24.

Transduction with human telomerase reverse transcriptase immortalizes a rhesus macaque CD8+ T cell clone with maintenance of surface marker phenotype and function.

Andersen H, Barsov EV, Trivett MT, Trubey CM, Giavedoni LD, Lifson JD, Ott DE, Ohlén C.

AIDS Res Hum Retroviruses. 2007 Mar;23(3):456-65.

PMID:
17411379
25.

CpG oligodeoxynucleotides allow for effective adoptive T-cell therapy in chronic retroviral infection.

Kraft AR, Krux F, Schimmer S, Ohlen C, Greenberg PD, Dittmer U.

Blood. 2007 Apr 1;109(7):2982-4.

PMID:
17148590
26.

Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors.

Teague RM, Sather BD, Sacks JA, Huang MZ, Dossett ML, Morimoto J, Tan X, Sutton SE, Cooke MP, Ohlén C, Greenberg PD.

Nat Med. 2006 Mar;12(3):335-41. Epub 2006 Feb 12.

PMID:
16474399
27.

Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infection.

Dittmer U, He H, Messer RJ, Schimmer S, Olbrich AR, Ohlen C, Greenberg PD, Stromnes IM, Iwashiro M, Sakaguchi S, Evans LH, Peterson KE, Yang G, Hasenkrug KJ.

Immunity. 2004 Mar;20(3):293-303. Erratum in: Immunity. 2004 May;20(5):653.

28.

Multigene DNA priming-boosting vaccines protect macaques from acute CD4+-T-cell depletion after simian-human immunodeficiency virus SHIV89.6P mucosal challenge.

Doria-Rose NA, Ohlen C, Polacino P, Pierce CC, Hensel MT, Kuller L, Mulvania T, Anderson D, Greenberg PD, Hu SL, Haigwood NL.

J Virol. 2003 Nov;77(21):11563-77.

29.

CD8(+) T cell tolerance to a tumor-associated antigen is maintained at the level of expansion rather than effector function.

Ohlén C, Kalos M, Cheng LE, Shur AC, Hong DJ, Carson BD, Kokot NC, Lerner CG, Sather BD, Huseby ES, Greenberg PD.

J Exp Med. 2002 Jun 3;195(11):1407-18.

31.

A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis.

Huseby ES, Liggitt D, Brabb T, Schnabel B, Ohlén C, Goverman J.

J Exp Med. 2001 Sep 3;194(5):669-76.

33.

Dendritic cells lose ability to present protein antigen after stimulating antigen-specific T cell responses, despite upregulation of MHC class II expression.

Bernhard H, Huseby ES, Hand SL, Lohmann M, Batten WY, Disis ML, Gralow JR, Meyer zum Büschenfelde KH, Ohlén C, Cheever MA.

Immunobiology. 2000 Apr;201(5):568-82.

PMID:
10834314
34.
36.

Genetic modification of T-cell clones for therapy of human viral and malignant diseases.

Greenberg PD, Finch RJ, Gavin MA, Kalos M, Lewinsohn DA, Lonergan M, Lord JD, Nelson BH, Ohlén C, Sing AP, Warren EH, Yee C, Riddell SR.

Cancer J Sci Am. 1998 May;4 Suppl 1:S100-5. No abstract available.

PMID:
9619278
37.

Host MHC class I gene control of NK-cell specificity in the mouse.

Höglund P, Sundbäck J, Olsson-Alheim MY, Johansson M, Salcedo M, Ohlén C, Ljunggren HG, Sentman CL, Kärre K.

Immunol Rev. 1997 Feb;155:11-28. Review.

PMID:
9059879
38.

Inhibition of natural killer cell-mediated bone marrow graft rejection by allogeneic major histocompatibility complex class I, but not class II molecules.

Ohlén C, Höglund P, Sentman CL, Carbone E, Ljunggren HG, Koller B, Kärre K.

Eur J Immunol. 1995 May;25(5):1286-91.

PMID:
7774631
39.

Source of unique tumour antigens.

Townsend A, Ohlén C, Rogers M, Edwards J, Mukherjee S, Bastin J.

Nature. 1994 Oct 20;371(6499):662. No abstract available.

PMID:
7935811
41.

Major histocompatibility complex class I-specific and -restricted killing of beta 2-microglobulin-deficient cells by CD8+ cytotoxic T lymphocytes.

Glas R, Franksson L, Ohlén C, Höglund P, Koller B, Ljunggren HG, Kärre K.

Proc Natl Acad Sci U S A. 1992 Dec 1;89(23):11381-5.

42.

Allorecognition by NK cells: nonself or no self?

Moretta L, Ciccone E, Moretta A, Höglund P, Ohlén C, Kärre K.

Immunol Today. 1992 Aug;13(8):300-6. Review.

PMID:
1380815
43.
44.

Different types of allospecific CTL clones identified by their ability to recognize peptide loading-defective target cells.

Aosai F, Ohlen C, Ljunggren HG, Höglund P, Franksson L, Ploegh H, Townsend A, Kärre K, Stauss HJ.

Eur J Immunol. 1991 Nov;21(11):2767-74.

PMID:
1936122
46.

The RMA-S lymphoma mutant; consequences of a peptide loading defect on immunological recognition and graft rejection.

Ljunggren HG, Ohlén C, Höglund P, Franksson L, Kärre K.

Int J Cancer Suppl. 1991;6:38-44.

PMID:
2066183
47.

Antigen presentation and the association of class-I molecules.

Elliott TJ, Cerundolo V, Ohlen C, Ljunggren HG, Karre K, Townsend A.

Acta Biol Hung. 1991;42(1-3):213-29.

PMID:
1726936
48.

Empty MHC class I molecules come out in the cold.

Ljunggren HG, Stam NJ, Ohlén C, Neefjes JJ, Höglund P, Heemels MT, Bastin J, Schumacher TN, Townsend A, Kärre K, et al.

Nature. 1990 Aug 2;346(6283):476-80.

PMID:
2198471
49.

Restoration of H-2b expression and processing of endogenous antigens in the MHC class I pathway by fusion of a lymphoma mutant to L cells of the H-2k haplotype.

Ohlén C, Bastin J, Ljunggren HG, Imreh S, Klein G, Townsend AR, Kärre K.

Eur J Immunol. 1990 Aug;20(8):1873-6.

PMID:
2120065
50.

Resistance to H-2-restricted but not to allo-H2-specific graft and cytotoxic T lymphocyte responses in lymphoma mutant.

Ohlén C, Bastin J, Ljunggren HG, Foster L, Wolpert E, Klein G, Townsend AR, Kärre K.

J Immunol. 1990 Jul 1;145(1):52-8.

PMID:
2358681

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