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Items: 1 to 50 of 193

1.

Combining microscopy and biochemistry to study meiotic spindle assembly in Drosophila oocytes.

Romé P, Ohkura H.

Methods Cell Biol. 2018;145:237-248. doi: 10.1016/bs.mcb.2018.03.026. Epub 2018 Apr 11.

2.

14-3-3 regulation of Ncd reveals a new mechanism for targeting proteins to the spindle in oocytes.

Beaven R, Bastos RN, Spanos C, Romé P, Cullen CF, Rappsilber J, Giet R, Goshima G, Ohkura H.

J Cell Biol. 2017 Oct 2;216(10):3029-3039. doi: 10.1083/jcb.201704120. Epub 2017 Aug 31.

3.

Adipose tissue-derived multi-lineage progenitor cells improve left ventricular dysfunction in porcine ischemic cardiomyopathy model.

Shudo Y, Miyagawa S, Ohkura H, Fukushima S, Saito A, Kawaguchi N, Matsuura N, Toda K, Sakaguchi T, Nishi H, Yoshikawa Y, Shimizu T, Okano T, Matsuyama A, Sawa Y.

J Heart Lung Transplant. 2017 Feb;36(2):237-239. doi: 10.1016/j.healun.2016.11.012. Epub 2016 Dec 6. No abstract available.

PMID:
28159019
4.

Kdm5/Lid Regulates Chromosome Architecture in Meiotic Prophase I Independently of Its Histone Demethylase Activity.

Zhaunova L, Ohkura H, Breuer M.

PLoS Genet. 2016 Aug 5;12(8):e1006241. doi: 10.1371/journal.pgen.1006241. eCollection 2016 Aug.

5.

The microtubule catastrophe promoter Sentin delays stable kinetochore-microtubule attachment in oocytes.

Głuszek AA, Cullen CF, Li W, Battaglia RA, Radford SJ, Costa MF, McKim KS, Goshima G, Ohkura H.

J Cell Biol. 2015 Dec 21;211(6):1113-20. doi: 10.1083/jcb.201507006. Epub 2015 Dec 14.

6.

Lateral and End-On Kinetochore Attachments Are Coordinated to Achieve Bi-orientation in Drosophila Oocytes.

Radford SJ, Hoang TL, Głuszek AA, Ohkura H, McKim KS.

PLoS Genet. 2015 Oct 16;11(10):e1005605. doi: 10.1371/journal.pgen.1005605. eCollection 2015 Oct.

7.

A negative loop within the nuclear pore complex controls global chromatin organization.

Breuer M, Ohkura H.

Genes Dev. 2015 Sep 1;29(17):1789-94. doi: 10.1101/gad.264341.115.

8.

Accurate chromosome segregation by probabilistic self-organisation.

Saka Y, Giuraniuc CV, Ohkura H.

BMC Biol. 2015 Aug 12;13:65. doi: 10.1186/s12915-015-0172-y.

9.

Drosophila CLIP-190 and mammalian CLIP-170 display reduced microtubule plus end association in the nervous system.

Beaven R, Dzhindzhev NS, Qu Y, Hahn I, Dajas-Bailador F, Ohkura H, Prokop A.

Mol Biol Cell. 2015 Apr 15;26(8):1491-508. doi: 10.1091/mbc.E14-06-1083. Epub 2015 Feb 18.

10.

Meiosis: an overview of key differences from mitosis.

Ohkura H.

Cold Spring Harb Perspect Biol. 2015 Jan 20;7(5). pii: a015859. doi: 10.1101/cshperspect.a015859. Review.

11.
12.

Bezafibrate improves insulin resistance evaluated using the glucose clamp technique in patients with type 2 diabetes mellitus: a small-scale clinical study.

Shiochi H, Ohkura T, Fujioka Y, Sumi K, Yamamoto N, Nakanishi R, Matsuzawa K, Izawa S, Ohkura H, Inoue K, Ueta E, Kato M, Taniguchi S, Yamamoto K.

Diabetol Metab Syndr. 2014 Oct 17;6(1):113. doi: 10.1186/1758-5996-6-113. eCollection 2014.

13.

Low serum galectin-3 concentrations are associated with insulin resistance in patients with type 2 diabetes mellitus.

Ohkura T, Fujioka Y, Nakanishi R, Shiochi H, Sumi K, Yamamoto N, Matsuzawa K, Izawa S, Ohkura H, Ueta E, Kato M, Miyoshi E, Taniguchi S, Yamamoto K.

Diabetol Metab Syndr. 2014 Sep 27;6(1):106. doi: 10.1186/1758-5996-6-106. eCollection 2014.

14.

Kank Is an EB1 interacting protein that localises to muscle-tendon attachment sites in Drosophila.

Clohisey SM, Dzhindzhev NS, Ohkura H.

PLoS One. 2014 Sep 9;9(9):e106112. doi: 10.1371/journal.pone.0106112. eCollection 2014. Erratum in: PLoS One. 2014;9(12):e114770.

15.

Implication of intracellular localization of transcriptional repressor PLZF in thyroid neoplasms.

Matsuzawa K, Izawa S, Ohkura T, Ohkura H, Ishiguro K, Yoshida A, Takiyama Y, Haneda M, Shigemasa C, Yamamoto K, Taniguchi S.

BMC Endocr Disord. 2014 Jul 3;14:52. doi: 10.1186/1472-6823-14-52.

16.

[A case of micafungin-hyposensitive Candida glabrata due to FKS2 gene mutation].

Inui S, Nakamura T, Tanabe K, Ohno H, Koike C, Okuda K, Nakata C, Fujimoto H, Ohkura H, Miyazaki Y, Takahashi H.

Kansenshogaku Zasshi. 2014 May;88(3 Suppl 9-10):6-10. Japanese.

PMID:
24979950
17.

Sitagliptin Improves the Impaired Acute Insulin Response during a Meal Tolerance Test in Japanese Patients with Type 2 Diabetes Mellitus: A Small-Scale Real-World Study.

Ohkura T, Fujioka Y, Sumi K, Nakanishi R, Shiochi H, Yamamoto N, Matsuzawa K, Izawa S, Ohkura H, Kato M, Taniguchi S, Yamamoto K.

Diabetes Ther. 2014 Jun;5(1):285-97. doi: 10.1007/s13300-014-0071-1. Epub 2014 Jun 3.

18.

Peptide aptamers define distinct EB1- and EB3-binding motifs and interfere with microtubule dynamics.

Leśniewska K, Warbrick E, Ohkura H.

Mol Biol Cell. 2014 Apr;25(7):1025-36. doi: 10.1091/mbc.E13-08-0504. Epub 2014 Jan 29.

19.

In vivo siRNA delivery system for targeting to the liver by poly-l-glutamic acid-coated lipoplex.

Hattori Y, Nakamura A, Arai S, Nishigaki M, Ohkura H, Kawano K, Maitani Y, Yonemochi E.

Results Pharma Sci. 2014 Jan 25;4:1-7. doi: 10.1016/j.rinphs.2014.01.001. eCollection 2014.

20.

The proinsulin/insulin (PI/I) ratio is reduced by postprandial targeting therapy in type 2 diabetes mellitus: a small-scale clinical study.

Ohkura T, Inoue K, Fujioka Y, Nakanishi R, Shiochi H, Sumi K, Yamamoto N, Matsuzawa K, Izawa S, Ohkura H, Kato M, Yamamoto K, Taniguchi S.

BMC Res Notes. 2013 Nov 11;6:453. doi: 10.1186/1756-0500-6-453.

21.

Addition of mesenchymal stem cells enhances the therapeutic effects of skeletal myoblast cell-sheet transplantation in a rat ischemic cardiomyopathy model.

Shudo Y, Miyagawa S, Ohkura H, Fukushima S, Saito A, Shiozaki M, Kawaguchi N, Matsuura N, Shimizu T, Okano T, Matsuyama A, Sawa Y.

Tissue Eng Part A. 2014 Feb;20(3-4):728-39. doi: 10.1089/ten.TEA.2012.0534. Epub 2014 Jan 3.

22.

Lissencephaly-1 promotes the recruitment of dynein and dynactin to transported mRNAs.

Dix CI, Soundararajan HC, Dzhindzhev NS, Begum F, Suter B, Ohkura H, Stephens E, Bullock SL.

J Cell Biol. 2013 Aug 5;202(3):479-94. doi: 10.1083/jcb.201211052.

23.

Cell cycle regulation of microtubule interactomes: multi-layered regulation is critical for the interphase/mitosis transition.

Syred HM, Welburn J, Rappsilber J, Ohkura H.

Mol Cell Proteomics. 2013 Nov;12(11):3135-47. doi: 10.1074/mcp.M113.028563. Epub 2013 Jul 26.

24.

Meiosis-specific stable binding of augmin to acentrosomal spindle poles promotes biased microtubule assembly in oocytes.

Colombié N, Głuszek AA, Meireles AM, Ohkura H.

PLoS Genet. 2013 Jun;9(6):e1003562. doi: 10.1371/journal.pgen.1003562. Epub 2013 Jun 13.

25.

20/(fasting C-peptide × fasting plasma glucose) is a simple and effective index of insulin resistance in patients with type 2 diabetes mellitus: a preliminary report.

Ohkura T, Shiochi H, Fujioka Y, Sumi K, Yamamoto N, Matsuzawa K, Izawa S, Kinoshita H, Ohkura H, Kato M, Taniguchi S, Yamamoto K.

Cardiovasc Diabetol. 2013 Jan 22;12:21. doi: 10.1186/1475-2840-12-21.

26.

Autoantibody against WD repeat domain 1 is a novel serological biomarker for screening of thyroid neoplasia.

Izawa S, Okamura T, Matsuzawa K, Ohkura T, Ohkura H, Ishiguro K, Noh JY, Kamijo K, Yoshida A, Shigemasa C, Kato M, Yamamoto K, Taniguchi S.

Clin Endocrinol (Oxf). 2013 Jul;79(1):35-42. doi: 10.1111/cen.12121. Epub 2013 May 6.

PMID:
23215816
27.

Dgp71WD is required for the assembly of the acentrosomal Meiosis I spindle, and is not a general targeting factor for the γ-TuRC.

Reschen RF, Colombie N, Wheatley L, Dobbelaere J, St Johnston D, Ohkura H, Raff JW.

Biol Open. 2012 May 15;1(5):422-9. doi: 10.1242/bio.2012596. Epub 2012 Mar 6.

28.

The conserved kinase SRPK regulates karyosome formation and spindle microtubule assembly in Drosophila oocytes.

Loh BJ, Cullen CF, Vogt N, Ohkura H.

J Cell Sci. 2012 Oct 1;125(Pt 19):4457-62. doi: 10.1242/jcs.107979. Epub 2012 Aug 1.

29.

Kinase activity of fission yeast Mph1 is required for Mad2 and Mad3 to stably bind the anaphase promoting complex.

Zich J, Sochaj AM, Syred HM, Milne L, Cook AG, Ohkura H, Rappsilber J, Hardwick KG.

Curr Biol. 2012 Feb 21;22(4):296-301. doi: 10.1016/j.cub.2011.12.049. Epub 2012 Jan 25.

30.

[Macrolide resistance and detection in Mycoplasma pneumoniae at Kansai Medical University Hirakata Hospital].

Koike C, Nakamura T, Inui S, Okuda K, Nakata C, Fujimoto H, Ohkura H, Hasui M, Takahashi H.

Kansenshogaku Zasshi. 2011 Nov;85(6):652-7. Japanese.

PMID:
22250456
31.

Kebab: kinetochore and EB1 associated basic protein that dynamically changes its localisation during Drosophila mitosis.

Meireles AM, Dzhindzhev NS, Ohkura H.

PLoS One. 2011;6(9):e24174. doi: 10.1371/journal.pone.0024174. Epub 2011 Sep 2.

32.

A PAR-1-dependent orientation gradient of dynamic microtubules directs posterior cargo transport in the Drosophila oocyte.

Parton RM, Hamilton RS, Ball G, Yang L, Cullen CF, Lu W, Ohkura H, Davis I.

J Cell Biol. 2011 Jul 11;194(1):121-35. doi: 10.1083/jcb.201103160.

33.

[A case of micafungin-hyposensitive Candida glabrata due to FKS2 gene mutation].

Inui S, Nakamura T, Tanabe K, Ohno H, Koike C, Okuda K, Nakata C, Fujimoto H, Ohkura H, Miyazaki Y, Takahashi H.

Kansenshogaku Zasshi. 2011 Jan;85(1):49-53. Japanese.

PMID:
21404607
34.

The meiotic recombination checkpoint suppresses NHK-1 kinase to prevent reorganisation of the oocyte nucleus in Drosophila.

Lancaster OM, Breuer M, Cullen CF, Ito T, Ohkura H.

PLoS Genet. 2010 Oct 28;6(10):e1001179. doi: 10.1371/journal.pgen.1001179.

35.

Pitavastatin further decreases serum high-sensitive C-reactive protein levels in hypertensive patients with hypercholesterolemia treated with angiotensin II, type-1 receptor antagonists.

Yoshika M, Komiyama Y, Masuda M, Yokoi T, Masaki H, Ohkura H, Takahashi H.

Clin Exp Hypertens. 2010;32(6):341-6. doi: 10.3109/10641961003628460.

PMID:
21028996
36.

Wac: a new Augmin subunit required for chromosome alignment but not for acentrosomal microtubule assembly in female meiosis.

Meireles AM, Fisher KH, Colombié N, Wakefield JG, Ohkura H.

J Cell Biol. 2009 Mar 23;184(6):777-84. doi: 10.1083/jcb.200811102. Epub 2009 Mar 16.

37.

Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes.

Satoh D, Sato D, Tsuyama T, Saito M, Ohkura H, Rolls MM, Ishikawa F, Uemura T.

Nat Cell Biol. 2008 Oct;10(10):1164-71. doi: 10.1038/ncb1776. Epub 2008 Aug 31.

PMID:
18758452
38.

Dual roles of Incenp crucial to the assembly of the acentrosomal metaphase spindle in female meiosis.

Colombié N, Cullen CF, Brittle AL, Jang JK, Earnshaw WC, Carmena M, McKim K, Ohkura H.

Development. 2008 Oct;135(19):3239-46. doi: 10.1242/dev.022624. Epub 2008 Aug 28.

39.

A microtubule interactome: complexes with roles in cell cycle and mitosis.

Hughes JR, Meireles AM, Fisher KH, Garcia A, Antrobus PR, Wainman A, Zitzmann N, Deane C, Ohkura H, Wakefield JG.

PLoS Biol. 2008 Apr 22;6(4):e98. doi: 10.1371/journal.pbio.0060098.

40.

Regulation of gene expression during M-G1-phase in fission yeast through Plo1p and forkhead transcription factors.

Papadopoulou K, Ng SS, Ohkura H, Geymonat M, Sedgwick SG, McInerny CJ.

J Cell Sci. 2008 Jan 1;121(Pt 1):38-47. Epub 2007 Dec 4.

41.

NHK-1 phosphorylates BAF to allow karyosome formation in the Drosophila oocyte nucleus.

Lancaster OM, Cullen CF, Ohkura H.

J Cell Biol. 2007 Dec 3;179(5):817-24. Epub 2007 Nov 26.

42.

Concerted action of Aurora B, Polo and NHK-1 kinases in centromere-specific histone 2A phosphorylation.

Brittle AL, Nanba Y, Ito T, Ohkura H.

Exp Cell Res. 2007 Aug 1;313(13):2780-5. Epub 2007 May 25.

43.

Hsp90 is required to localise cyclin B and Msps/ch-TOG to the mitotic spindle in Drosophila and humans.

Basto R, Gergely F, Draviam VM, Ohkura H, Liley K, Raff JW.

J Cell Sci. 2007 Apr 1;120(Pt 7):1278-87.

44.

Polarized transport of Frizzled along the planar microtubule arrays in Drosophila wing epithelium.

Shimada Y, Yonemura S, Ohkura H, Strutt D, Uemura T.

Dev Cell. 2006 Feb;10(2):209-22.

45.

Non-centrosomal microtubule-organising centres in cold-treated cultured Drosophila cells.

Cottam DM, Tucker JB, Rogers-Bald MM, Mackie JB, Macintyre J, Scarborough JA, Ohkura H, Milner MJ.

Cell Motil Cytoskeleton. 2006 Feb;63(2):88-100.

PMID:
16385467
46.

Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase.

Page AR, Kovacs A, Deak P, Torok T, Kiss I, Dario P, Bastos C, Batista P, Gomes R, Ohkura H, Russell S, Glover DM.

EMBO J. 2005 Dec 21;24(24):4304-15. Epub 2005 Nov 24.

47.
48.

Centrosome maturation: Aurora lights the way to the poles.

Brittle AL, Ohkura H.

Curr Biol. 2005 Nov 8;15(21):R880-2. Review.

49.
50.

A pre-anaphase role for a Cks/Suc1 in acentrosomal spindle formation of Drosophila female meiosis.

Pearson NJ, Cullen CF, Dzhindzhev NS, Ohkura H.

EMBO Rep. 2005 Nov;6(11):1058-63. Epub 2005 Sep 9.

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