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Items: 1 to 50 of 67

1.

The diversity of receptor recognition in cholesterol-dependent cytolysins.

Tabata A, Ohkura K, Ohkubo Y, Tomoyasu T, Ohkuni H, Whiley RA, Nagamune H.

Microbiol Immunol. 2014 Mar;58(3):155-71. doi: 10.1111/1348-0421.12131.

2.

Characterization of recombinant Streptococcus mitis-derived human platelet aggregation factor.

Ohkuni H, Nagamune H, Ozaki N, Tabata A, Todome Y, Watanabe Y, Takahashi H, Ohkura K, Kourai H, Ohtsuka H, Fischetti VA, Zabriskie JB.

APMIS. 2012 Jan;120(1):56-71. doi: 10.1111/j.1600-0463.2011.02813.x. Epub 2011 Sep 27.

PMID:
22151309
3.

Use of a dual priming oligonucleotide system to detect multiple sexually transmitted pathogens in clinical specimens.

Horii T, Ohtsuka H, Osaki M, Ohkuni H.

Lett Appl Microbiol. 2009 Jul;49(1):46-52. doi: 10.1111/j.1472-765X.2009.02618.x. Epub 2009 Apr 17.

4.

[Evaluation of the GonoGen II kit for rapid identification of Neisseria gonorrhoeae using monoclonal antibody directed at gonococcal outer membrane protein 1].

Tsuruoka N, Uzawa Y, Kikuchi K, Ohtsuka H, Todome Y, Ohkuni H.

Kansenshogaku Zasshi. 2008 Jul;82(4):317-21. Japanese.

PMID:
18697483
5.

Molecular basis of group A streptococcal pyrogenic exotoxin B.

Nagamune H, Ohkura K, Ohkuni H.

J Infect Chemother. 2005 Feb;11(1):1-8. Review. No abstract available.

PMID:
15729480
6.

Studies of recombinant streptococcal pyrogenic exotoxin B/cysteine protease (rSPE B/SCP) in the skin of guinea pigs & the release of histamine from cultured mast cells & basophilic leukocytes.

Ohkuni H, Todome Y, Watanabe Y, Ishikaw T, Takahashi H, Kannari Y, Kato H, Uchiyama T, Saito H, Fischetti VA, Zabriskie JB.

Indian J Med Res. 2004 May;119 Suppl:33-6.

PMID:
15232159
7.

[Prevention of pathogenic bacterial infection by using phage lytic enzyimes].

Ohkuni H.

J Nippon Med Sch. 2004 Feb;71(1):4. Japanese. No abstract available.

PMID:
15129588
8.
9.

Genetic polymorphisms of CYP2C8 in Japanese population.

Nakajima M, Fujiki Y, Noda K, Ohtsuka H, Ohkuni H, Kyo S, Inoue M, Kuroiwa Y, Yokoi T.

Drug Metab Dispos. 2003 Jun;31(6):687-90.

PMID:
12756196
10.

Moderate hypothermia delays proinflammatory cytokine production of human peripheral blood mononuclear cells.

Kimura A, Sakurada S, Ohkuni H, Todome Y, Kurata K.

Crit Care Med. 2002 Jul;30(7):1499-502.

PMID:
12130969
11.

Cysteine protease activity and histamine release from the human mast cell line HMC-1 stimulated by recombinant streptococcal pyrogenic exotoxin B/streptococcal cysteine protease.

Watanabe Y, Todome Y, Ohkuni H, Sakurada S, Ishikawa T, Yutsudo T, Fischetti VA, Zabriskie JB.

Infect Immun. 2002 Jul;70(7):3944-7.

12.

Synergistic bactericidal effects of acrinol and tetracycline against Pseudomonas aeruginosa.

Saji M, Fujii K, Ohkuni H, Irie N, Osono E, Kato F.

J Infect Chemother. 2000 Jun;6(2):86-92.

PMID:
11810541
13.

Effective human herpesvirus 8 infection of human umbilical vein endothelial cells by cell-mediated transmission.

Sakurada S, Katano H, Sata T, Ohkuni H, Watanabe T, Mori S.

J Virol. 2001 Aug;75(16):7717-22.

14.

Streptococcal toxic shock syndrome in a patient with rheumatoid arthritis.

Morishita M, Yamahatsu S, Yoshino S, Ohkuni H, Nagashima M.

Clin Exp Rheumatol. 2001 Mar-Apr;19(2):231-2. No abstract available.

PMID:
11326498
15.

[Clinical and fundamental studies of streptococcal toxic shock syndrome].

Ohkuni H.

Nihon Rinsho. 2001 Apr;59(4):808-18. Review. Japanese.

PMID:
11305011
16.

Clonotypes of Staphylococcus aureus isolated from continuous ambulatory peritoneal dialysis patients: what is the vector between nares and infection site?

Nakamura M, Watanabe Y, Osono E, Ohwada K, Kurihara S, Toume K, Yoneshima H, Ohkuni H.

Adv Perit Dial. 2000;16:248-51.

PMID:
11045304
17.

[Flesh-eating bacteria: streptococcal toxic shock syndrome].

Ohkuni H.

J Nippon Med Sch. 2000 Oct;67(5):371-4. Review. Japanese. No abstract available.

18.

Effects of "isolating hemodialysis" on prevention of methicillin-resistant Staphylococcus aureus cross-infection in a hemodialysis unit.

Osono E, Takahashi M, Kurihara S, Ohwada K, Sakurai Y, Onoda N, Takeuchi M, Yoneshima H, Hayama N, Iino Y, Saji M, Shikita R, Takahashi H, Ohkuni H.

Clin Nephrol. 2000 Aug;54(2):128-33.

PMID:
10968688
19.

Streptococcus peroris sp. nov. and Streptococcus infantis sp. nov., new members of the Streptococcus mitis group, isolated from human clinical specimens.

Kawamura Y, Hou XG, Todome Y, Sultana F, Hirose K, Shu SE, Ezaki T, Ohkuni H.

Int J Syst Bacteriol. 1998 Jul;48 Pt 3:921-7.

PMID:
9734047
20.

[Report of surveillance on streptococcal toxic shock syndrome in Japan and presentation of the criteria].

Shimizu Y, Igarashi H, Murai T, Ohkuni H, Watanabe H, Uchiyama T, Ooe K.

Kansenshogaku Zasshi. 1998 Mar;72(3):258-65. Japanese.

PMID:
9585700
21.

Purification and partial characterization of a novel human platelet aggregation factor in the extracellular products of Streptococcus mitis, strain Nm-65.

Ohkuni H, Todome Y, Okibayashi F, Watanabe Y, Ohtani N, Ishikawa T, Asano G, Kotani S.

FEMS Immunol Med Microbiol. 1997 Feb;17(2):121-9.

22.

Purification and partial characterization of a novel human platelet aggregation factor in the extracellular products of Streptococcus mitis, strain Nm-65.

Ohkuni H, Todome Y, Watanabe Y, Kotani S, Kimura Y.

Adv Exp Med Biol. 1997;418:689-93. No abstract available.

PMID:
9331745
23.

Possible pathogenic effect of Streptococcus mitis superantigen on oral epithelial cells.

Matsushita K, Uchiyama T, Igarashi H, Ohkuni H, Nagaoka S, Kotani S, Takada H.

Adv Exp Med Biol. 1997;418:685-8. No abstract available.

PMID:
9331744
24.

[Group A Streptococcus and autoimmune].

Ohkuni H.

Ryumachi. 1996 Dec;36(6):874-83. Review. Japanese. No abstract available.

PMID:
9122828
25.

Induction of lymphocytes cytotoxic to oral epithelial cells by Streptococcus mitis superantigen.

Matsushita K, Sugiyama A, Uchiyama T, Igarashi H, Ohkuni H, Nagaoka S, Kotani S, Takada H.

J Dent Res. 1996 Mar;75(3):927-34.

PMID:
8675804
26.

Adjuvant activities of pyrene, anthracene, fluoranthene and benzo(a)pyrene in production of anti-IgE antibody to Japanese cedar pollen allergen in mice.

Kanoh T, Suzuki T, Ishimori M, Ikeda S, Ohasawa M, Ohkuni H, Tunetoshi Y.

J Clin Lab Immunol. 1996;48(4):133-47.

PMID:
9819666
27.

Adjuvant activity of diesel exhaust particulates (DEP) in production of anti-IgE and anti-IgG1 antibodies to mite allergen in mice.

Suzuki T, Kanoh T, Ishimori M, Ikeda S, Ohkuni H.

J Clin Lab Immunol. 1996;48(5):187-99.

PMID:
9394242
28.

Efficacy of gentian violet in the eradication of methicillin-resistant Staphylococcus aureus from skin lesions.

Saji M, Taguchi S, Uchiyama K, Osono E, Hayama N, Ohkuni H.

J Hosp Infect. 1995 Nov;31(3):225-8.

PMID:
8586792
29.

Alveolar fibrosis and capillary alteration in experimental pulmonary silicosis in rats.

Kawanami O, Jiang HX, Mochimaru H, Yoneyama H, Kudoh S, Ohkuni H, Ooami H, Ferrans VJ.

Am J Respir Crit Care Med. 1995 Jun;151(6):1946-55.

PMID:
7767544
30.

Immunopathological activities of extracellular products of Streptococcus mitis, particularly a superantigenic fraction.

Matsushita K, Fujimaki W, Kato H, Uchiyama T, Igarashi H, Ohkuni H, Nagaoka S, Kawagoe M, Kotani S, Takada H.

Infect Immun. 1995 Mar;63(3):785-93.

31.

Superantigenic exotoxin production by isolates of Staphylococcus aureus from the Kawasaki syndrome patients and age-matched control children.

Todome Y, Ohkuni H, Mizuse M, Okibayashi F, Ohtani N, Suzuki H, Song C, Igarashi H, Harada K, Sakurai S, et al.

J Med Microbiol. 1995 Feb;42(2):91-5.

PMID:
7869353
32.

[Bactericidal effects of gentian violet (Gv) and acrinol (Ac) against methicillin-resistant Staphylococcus aureus (MRSA) and gram-negative bacteria isolated from clinical materials].

Saji M, Taguchi S, Shikida R, Ohkuni H.

Kansenshogaku Zasshi. 1994 Oct;68(10):1287-9. Japanese. No abstract available.

PMID:
7996029
33.

[Formidable streptococcal infections].

Ohkuni H, Igarashi H, Ohe K.

Nihon Saikingaku Zasshi. 1994 Sep;49(5-6):759-67. Review. Japanese. No abstract available.

PMID:
7830319
34.

[Synergism on the bactericidal effect of gentian violet (Gv) and acrinol (Ac) against Pseudomonas aeruginosa].

Saji M, Taguchi S, Ohkuni H.

Kansenshogaku Zasshi. 1994 Aug;68(8):953-9. Japanese.

PMID:
7930786
35.

The presence of tumor necrosis factor-alpha and its antibody in the sera of cachexic patients with gastrointestinal cancer.

Kiyama T, Onda M, Tokunaga A, Fujita I, Okuda T, Mizutani T, Matsukura N, Todome Y, Ohkuni H.

Surg Today. 1994;24(8):759-62.

PMID:
7981552
36.

Cytokine induction by extracellular products of oral viridans group streptococci.

Takada H, Kawabata Y, Tamura M, Matsushita K, Igarashi H, Ohkuni H, Todome Y, Uchiyama T, Kotani S.

Infect Immun. 1993 Dec;61(12):5252-60.

37.

Biologically active extracellular products of oral viridans streptococci and the aetiology of Kawasaki disease.

Ohkuni H, Todome Y, Mizuse M, Ohtani N, Suzuki H, Igarashi H, Hashimoto Y, Ezaki T, Harada K, Imada Y, et al.

J Med Microbiol. 1993 Nov;39(5):352-62.

PMID:
8246252
38.

[Effect of gentian violet on the elimination of methicillin-resistant Staphylococcus aureus (MRSA) existing in the decubitus region].

Saji M, Taguchi S, Hayama N, Ohzono E, Kobayashi Y, Uchiyama K, Kanekawa T, Ohkuni H.

Nihon Ronen Igakkai Zasshi. 1993 Sep;30(9):795-801. Japanese.

39.

[Adhesion ultrastructures of mononuclear cells in experimentally-induced silicotic granuloma].

Yoneyama H, Kawanami O, Usuki J, Furuta T, Ohkuni H, Todome Y, Ooami H.

Arerugi. 1993 Aug;42(8):955-62. Japanese.

PMID:
8250736
40.

The adjuvant activity of pyrene in diesel exhaust on IgE antibody production in mice.

Suzuki T, Kanoh T, Kanbayashi M, Todome Y, Ohkuni H.

Arerugi. 1993 Aug;42(8):963-8.

PMID:
7504446
41.

Detection of antibodies against streptococcal peptidoglycan and the peptide subunit (synthetic tetra-D-alanyl-bovine serum albumin complex) in rheumatic-diseases.

Todome Y, Ohkuni H, Mizuse M, Furuya M, Fujikawa S, Tanaka S, Watanabe N, Fujii K, Zabriskie JB.

Int Arch Allergy Immunol. 1992;97(4):301-7.

PMID:
1597350
42.

Immunochemical studies and complete amino acid sequence of the streptokinase from Streptococcus pyogenes (group A) M type 12 strain A374.

Ohkuni H, Todome Y, Suzuki H, Mizuse M, Kotani N, Horiuchi K, Shikama N, Tsugita A, Johnston KH.

Infect Immun. 1992 Jan;60(1):278-83.

43.

Detection of nephritis strain-associated streptokinase by monoclonal antibodies.

Ohkuni H, Todome Y, Yoshimura K, Yamamoto T, Suzuki H, Yokomuro K, Johnston KH, Zabriskie JB.

J Med Microbiol. 1991 Jul;35(1):60-3.

PMID:
2072380
44.

Calculation of efficacy of acellular pertussis vaccine from the number of pertussis patients and vaccinees in three areas.

Ohkuni H, Yabiku M, Togawa M, Fukai K, Yosida I, Minekawa Y, Kitamura T.

Dev Biol Stand. 1991;73:43-9.

PMID:
1778332
45.

Relationship between bacterial meningitis and acellular pertussis vaccine.

Yabiku M, Ohkuni H, Shiomi M, Ishii T, Shimotuji T.

Dev Biol Stand. 1991;73:315-21.

PMID:
1778325
46.

[Non-specific host-defence mechanisms to streptococcal infection].

Ohkuni H.

Nihon Ika Daigaku Zasshi. 1989 Dec;56(6):529-34. Review. Japanese. No abstract available.

PMID:
2514190
47.

Etiology and clinical studies of lower respiratory infections.

Ohkuni H, Ogawa H, Ko YJ, Maeyama M, Yabiku M, Shiomi M, Imaishi H, Sugita T, Yamamoto K, Adachi T.

Acta Paediatr Jpn. 1988 Jun;30(3):240-6. No abstract available.

PMID:
3150207
48.

Enzyme-linked immunosorbent assay of antibody to group A Streptococcus-specific C carbohydrate with trypsin-pronase-treated whole cells as antigen.

Todome Y, Ohkuni H, Yokomuro K, Kimura Y, Hamada S, Johnston KH, Zabriskie JB.

J Clin Microbiol. 1988 Mar;26(3):464-70.

50.

Streptococcal antibody: as an indicator of tonsillectomy.

Fujikawa S, Hanawa Y, Ito H, Ohkuni M, Todome Y, Ohkuni H.

Acta Otolaryngol Suppl. 1988;454:286-91.

PMID:
3223262

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