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Items: 25

1.

[Cell surface pH imaging using poly(ethylene glycol)-phospholipid: its potential as the core structure of membrane anchored-probes].

Ohgaki R, Teramura Y, Hayashi D, Nagamori S, Takai M, Kanai Y.

Nihon Yakurigaku Zasshi. 2019;153(6):254-260. doi: 10.1254/fpj.153.254. Japanese.

PMID:
31178529
2.

Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc.

Lee Y, Wiriyasermkul P, Jin C, Quan L, Ohgaki R, Okuda S, Kusakizako T, Nishizawa T, Oda K, Ishitani R, Yokoyama T, Nakane T, Shirouzu M, Endou H, Nagamori S, Kanai Y, Nureki O.

Nat Struct Mol Biol. 2019 Jun;26(6):510-517. doi: 10.1038/s41594-019-0237-7. Epub 2019 Jun 3.

PMID:
31160781
3.

Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter.

Miyabe J, Ohgaki R, Saito K, Wei L, Quan L, Jin C, Liu X, Okuda S, Nagamori S, Ohki H, Yoshino K, Inohara H, Kanai Y.

J Pharmacol Sci. 2019 Mar;139(3):215-222. doi: 10.1016/j.jphs.2019.01.012. Epub 2019 Feb 18.

4.

Ratiometric fluorescence imaging of cell surface pH by poly(ethylene glycol)-phospholipid conjugated with fluorescein isothiocyanate.

Ohgaki R, Teramura Y, Hayashi D, Quan L, Okuda S, Nagamori S, Takai M, Kanai Y.

Sci Rep. 2017 Dec 13;7(1):17484. doi: 10.1038/s41598-017-17459-y.

5.

Essential Roles of L-Type Amino Acid Transporter 1 in Syncytiotrophoblast Development by Presenting Fusogenic 4F2hc.

Ohgaki R, Ohmori T, Hara S, Nakagomi S, Kanai-Azuma M, Kaneda-Nakashima K, Okuda S, Nagamori S, Kanai Y.

Mol Cell Biol. 2017 May 16;37(11). pii: e00427-16. doi: 10.1128/MCB.00427-16. Print 2017 Jun 1.

6.

Structure-activity relationship of a novel series of inhibitors for cancer type transporter L-type amino acid transporter 1 (LAT1).

Kongpracha P, Nagamori S, Wiriyasermkul P, Tanaka Y, Kaneda K, Okuda S, Ohgaki R, Kanai Y.

J Pharmacol Sci. 2017 Feb;133(2):96-102. doi: 10.1016/j.jphs.2017.01.006. Epub 2017 Feb 9.

7.

Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder.

Tărlungeanu DC, Deliu E, Dotter CP, Kara M, Janiesch PC, Scalise M, Galluccio M, Tesulov M, Morelli E, Sonmez FM, Bilguvar K, Ohgaki R, Kanai Y, Johansen A, Esharif S, Ben-Omran T, Topcu M, Schlessinger A, Indiveri C, Duncan KE, Caglayan AO, Gunel M, Gleeson JG, Novarino G.

Cell. 2016 Dec 1;167(6):1481-1494.e18. doi: 10.1016/j.cell.2016.11.013.

8.

Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 inhibitor Canagliflozin with SGLT1 and SGLT2.

Ohgaki R, Wei L, Yamada K, Hara T, Kuriyama C, Okuda S, Ueta K, Shiotani M, Nagamori S, Kanai Y.

J Pharmacol Exp Ther. 2016 Jul;358(1):94-102. doi: 10.1124/jpet.116.232025. Epub 2016 Apr 27.

PMID:
27189972
9.

Transport of 3-fluoro-L-α-methyl-tyrosine (FAMT) by organic ion transporters explains renal background in [(18)F]FAMT positron emission tomography.

Wei L, Tominaga H, Ohgaki R, Wiriyasermkul P, Hagiwara K, Okuda S, Kaira K, Kato Y, Oriuchi N, Nagamori S, Kanai Y.

J Pharmacol Sci. 2016 Feb;130(2):101-9. doi: 10.1016/j.jphs.2016.01.001. Epub 2016 Jan 21.

10.

Specific transport of 3-fluoro-l-α-methyl-tyrosine by LAT1 explains its specificity to malignant tumors in imaging.

Wei L, Tominaga H, Ohgaki R, Wiriyasermkul P, Hagiwara K, Okuda S, Kaira K, Oriuchi N, Nagamori S, Kanai Y.

Cancer Sci. 2016 Mar;107(3):347-52. doi: 10.1111/cas.12878. Epub 2016 Feb 19.

11.

Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1.

Nagamori S, Wiriyasermkul P, Guarch ME, Okuyama H, Nakagomi S, Tadagaki K, Nishinaka Y, Bodoy S, Takafuji K, Okuda S, Kurokawa J, Ohgaki R, Nunes V, Palacín M, Kanai Y.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):775-80. doi: 10.1073/pnas.1519959113. Epub 2016 Jan 6.

12.

Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling.

Nagamori S, Wiriyasermkul P, Okuda S, Kojima N, Hari Y, Kiyonaka S, Mori Y, Tominaga H, Ohgaki R, Kanai Y.

Amino Acids. 2016 Apr;48(4):1045-58. doi: 10.1007/s00726-015-2158-z. Epub 2016 Jan 2.

PMID:
26724922
13.

Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2.

Wongthai P, Hagiwara K, Miyoshi Y, Wiriyasermkul P, Wei L, Ohgaki R, Kato I, Hamase K, Nagamori S, Kanai Y.

Cancer Sci. 2015 Mar;106(3):279-86. doi: 10.1111/cas.12602. Epub 2015 Mar 6.

14.

Nicotine induces dendritic spine remodeling in cultured hippocampal neurons.

Oda A, Yamagata K, Nakagomi S, Uejima H, Wiriyasermkul P, Ohgaki R, Nagamori S, Kanai Y, Tanaka H.

J Neurochem. 2014 Jan;128(2):246-55. doi: 10.1111/jnc.12470. Epub 2013 Oct 24.

15.

NRFL-1, the C. elegans NHERF orthologue, interacts with amino acid transporter 6 (AAT-6) for age-dependent maintenance of AAT-6 on the membrane.

Hagiwara K, Nagamori S, Umemura YM, Ohgaki R, Tanaka H, Murata D, Nakagomi S, Nomura KH, Kage-Nakadai E, Mitani S, Nomura K, Kanai Y.

PLoS One. 2012;7(8):e43050. doi: 10.1371/journal.pone.0043050. Epub 2012 Aug 15.

16.

Establishment of stable cell lines with high expression of heterodimers of human 4F2hc and human amino acid transporter LAT1 or LAT2 and delineation of their differential interaction with α-alkyl moieties.

Khunweeraphong N, Nagamori S, Wiriyasermkul P, Nishinaka Y, Wongthai P, Ohgaki R, Tanaka H, Tominaga H, Sakurai H, Kanai Y.

J Pharmacol Sci. 2012;119(4):368-80. Epub 2012 Jul 31.

17.

Transport of 3-fluoro-L-α-methyl-tyrosine by tumor-upregulated L-type amino acid transporter 1: a cause of the tumor uptake in PET.

Wiriyasermkul P, Nagamori S, Tominaga H, Oriuchi N, Kaira K, Nakao H, Kitashoji T, Ohgaki R, Tanaka H, Endou H, Endo K, Sakurai H, Kanai Y.

J Nucl Med. 2012 Aug;53(8):1253-61. doi: 10.2967/jnumed.112.103069. Epub 2012 Jun 28.

18.

Linkage of N-cadherin to multiple cytoskeletal elements revealed by a proteomic approach in hippocampal neurons.

Tanaka H, Takafuji K, Taguchi A, Wiriyasermkul P, Ohgaki R, Nagamori S, Suh PG, Kanai Y.

Neurochem Int. 2012 Jul;61(2):240-50. doi: 10.1016/j.neuint.2012.05.008. Epub 2012 May 17.

PMID:
22609377
19.

Differential effects of TNF (TNFSF2) and IFN-γ on intestinal epithelial cell morphogenesis and barrier function in three-dimensional culture.

Juuti-Uusitalo K, Klunder LJ, Sjollema KA, Mackovicova K, Ohgaki R, Hoekstra D, Dekker J, van Ijzendoorn SC.

PLoS One. 2011;6(8):e22967. doi: 10.1371/journal.pone.0022967. Epub 2011 Aug 11.

20.

Organellar Na+/H+ exchangers: novel players in organelle pH regulation and their emerging functions.

Ohgaki R, van IJzendoorn SC, Matsushita M, Hoekstra D, Kanazawa H.

Biochemistry. 2011 Feb 1;50(4):443-50. doi: 10.1021/bi101082e. Epub 2010 Dec 30. Review.

PMID:
21171650
21.

[Localization, ion transport activity, and physiological function of mammalian organellar NHEs].

Ohgaki R, Matsushita M, Kanazawa H.

Seikagaku. 2010 Jul;82(7):577-90. Review. Japanese. No abstract available.

PMID:
20715570
22.

A membrane-proximal region in the C-terminal tail of NHE7 is required for its distribution in the trans-Golgi network, distinct from NHE6 localization at endosomes.

Fukura N, Ohgaki R, Matsushita M, Nakamura N, Mitsui K, Kanazawa H.

J Membr Biol. 2010 Apr;234(3):149-58. doi: 10.1007/s00232-010-9242-9. Epub 2010 Apr 3.

PMID:
20364249
23.

The Na+/H+ exchanger NHE6 in the endosomal recycling system is involved in the development of apical bile canalicular surface domains in HepG2 cells.

Ohgaki R, Matsushita M, Kanazawa H, Ogihara S, Hoekstra D, van Ijzendoorn SC.

Mol Biol Cell. 2010 Apr 1;21(7):1293-304. doi: 10.1091/mbc.E09-09-0767. Epub 2010 Feb 3.

24.

Cell surface levels of organellar Na+/H+ exchanger isoform 6 are regulated by interaction with RACK1.

Ohgaki R, Fukura N, Matsushita M, Mitsui K, Kanazawa H.

J Biol Chem. 2008 Feb 15;283(7):4417-29. Epub 2007 Dec 5.

25.

Characterization of the ion transport activity of the budding yeast Na+/H+ antiporter, Nha1p, using isolated secretory vesicles.

Ohgaki R, Nakamura N, Mitsui K, Kanazawa H.

Biochim Biophys Acta. 2005 Jun 30;1712(2):185-96. Epub 2005 Apr 14.

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