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Items: 15

1.

Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer.

Fujikane T, Nishikawa N, Toyota M, Suzuki H, Nojima M, Maruyama R, Ashida M, Ohe-Toyota M, Kai M, Nishidate T, Sasaki Y, Ohmura T, Hirata K, Tokino T.

Breast Cancer Res Treat. 2010 Aug;122(3):699-710. doi: 10.1007/s10549-009-0600-1. Epub 2009 Oct 27.

PMID:
19859801
2.

LINE-1 hypomethylation is associated with increased CpG island methylation in Helicobacter pylori-related enlarged-fold gastritis.

Yamamoto E, Toyota M, Suzuki H, Kondo Y, Sanomura T, Murayama Y, Ohe-Toyota M, Maruyama R, Nojima M, Ashida M, Fujii K, Sasaki Y, Hayashi N, Mori M, Imai K, Tokino T, Shinomura Y.

Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2555-64. doi: 10.1158/1055-9965.EPI-08-0112.

3.

Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer.

Maruyama R, Akino K, Toyota M, Suzuki H, Imai T, Ohe-Toyota M, Yamamoto E, Nojima M, Fujikane T, Sasaki Y, Yamashita T, Watanabe Y, Hiratsuka H, Hirata K, Itoh F, Imai K, Shinomura Y, Tokino T.

Carcinogenesis. 2008 Jul;29(7):1312-8. doi: 10.1093/carcin/bgn060. Epub 2008 Feb 29.

4.

Gene amplification and overexpression of PRDM14 in breast cancers.

Nishikawa N, Toyota M, Suzuki H, Honma T, Fujikane T, Ohmura T, Nishidate T, Ohe-Toyota M, Maruyama R, Sonoda T, Sasaki Y, Urano T, Imai K, Hirata K, Tokino T.

Cancer Res. 2007 Oct 15;67(20):9649-57.

5.

PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer.

Watanabe Y, Toyota M, Kondo Y, Suzuki H, Imai T, Ohe-Toyota M, Maruyama R, Nojima M, Sasaki Y, Sekido Y, Hiratsuka H, Shinomura Y, Imai K, Itoh F, Tokino T.

Clin Cancer Res. 2007 Aug 15;13(16):4786-94.

6.

Comparative genome analysis identifies the vitamin D receptor gene as a direct target of p53-mediated transcriptional activation.

Maruyama R, Aoki F, Toyota M, Sasaki Y, Akashi H, Mita H, Suzuki H, Akino K, Ohe-Toyota M, Maruyama Y, Tatsumi H, Imai K, Shinomura Y, Tokino T.

Cancer Res. 2006 May 1;66(9):4574-83.

7.

The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer.

Akino K, Toyota M, Suzuki H, Mita H, Sasaki Y, Ohe-Toyota M, Issa JP, Hinoda Y, Imai K, Tokino T.

Gastroenterology. 2005 Jul;129(1):156-69.

PMID:
16012945
8.

Identification of SCN3B as a novel p53-inducible proapoptotic gene.

Adachi K, Toyota M, Sasaki Y, Yamashita T, Ishida S, Ohe-Toyota M, Maruyama R, Hinoda Y, Saito T, Imai K, Kudo R, Tokino T.

Oncogene. 2004 Oct 14;23(47):7791-8.

PMID:
15334053
9.

Aberrant methylation of multiple genes and clinicopathological features in oral squamous cell carcinoma.

Ogi K, Toyota M, Ohe-Toyota M, Tanaka N, Noguchi M, Sonoda T, Kohama G, Tokino T.

Clin Cancer Res. 2002 Oct;8(10):3164-71.

10.

Aberrant methylation of the Cyclooxygenase 2 CpG island in colorectal tumors.

Toyota M, Shen L, Ohe-Toyota M, Hamilton SR, Sinicrope FA, Issa JP.

Cancer Res. 2000 Aug 1;60(15):4044-8.

11.

Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype.

Toyota M, Ohe-Toyota M, Ahuja N, Issa JP.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):710-5.

12.

Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype.

Toyota M, Ahuja N, Suzuki H, Itoh F, Ohe-Toyota M, Imai K, Baylin SB, Issa JP.

Cancer Res. 1999 Nov 1;59(21):5438-42.

13.

Inactivation of CACNA1G, a T-type calcium channel gene, by aberrant methylation of its 5' CpG island in human tumors.

Toyota M, Ho C, Ohe-Toyota M, Baylin SB, Issa JP.

Cancer Res. 1999 Sep 15;59(18):4535-41.

14.

CpG island methylator phenotype in colorectal cancer.

Toyota M, Ahuja N, Ohe-Toyota M, Herman JG, Baylin SB, Issa JP.

Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8681-6.

15.

Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification.

Toyota M, Ho C, Ahuja N, Jair KW, Li Q, Ohe-Toyota M, Baylin SB, Issa JP.

Cancer Res. 1999 May 15;59(10):2307-12.

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