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Genetic correction of induced pluripotent stem cells mediated by transcription activator-like effector nucleases targeting ALPL recovers enzyme activity and calcification in vitro.

Nakano C, Kitabatake Y, Takeyari S, Ohata Y, Kubota T, Taketani K, Kogo M, Ozono K.

Mol Genet Metab. 2019 May 28. pii: S1096-7192(19)30110-6. doi: 10.1016/j.ymgme.2019.05.014. [Epub ahead of print]


Effect of linagliptin on oxidative stress markers in patients with type 2 diabetes: a pilot study.

Makino H, Matsuo M, Hishida A, Koezuka R, Tochiya M, Ohata Y, Tamanaha T, Son C, Miyamoto Y, Hosoda K.

Diabetol Int. 2018 Sep 28;10(2):148-152. doi: 10.1007/s13340-018-0376-9. eCollection 2019 Apr.


Correction to "Anomalous Water Molecules and Mechanistic Effects of Water Nanotube Clusters Confined to Molecular Porous Crystals".

Tadokoro M, Ohhara T, Ohata Y, Suda T, Miyasato Y, Yamada T, Kikuchi T, Tanaka I, Kurihara K, Oguni M, Nakasuji K, Yamamuro O, Kuroki R.

J Phys Chem B. 2019 May 9;123(18):4157. doi: 10.1021/acs.jpcb.9b03433. Epub 2019 Apr 26. No abstract available.


A novel PTCH1 mutation in basal cell nevus syndrome with rare craniofacial features.

Murata Y, Kurosaka H, Ohata Y, Aikawa T, Takahata S, Fujii K, Miyashita T, Morita C, Inubushi T, Kubota T, Sakai N, Ozono K, Kogo M, Yamashiro T.

Hum Genome Var. 2019 Apr 2;6:16. doi: 10.1038/s41439-019-0047-9. eCollection 2019.


Metreleptin treatment for congenital generalized lipodystrophy type 4 (CGL4): a case report.

Takeyari S, Takakuwa S, Miyata K, Yamamoto K, Nakayama H, Ohata Y, Fujiwara M, Kitaoka T, Kubota T, Namba N, Sakai N, Ozono K.

Clin Pediatr Endocrinol. 2019;28(1):1-7. doi: 10.1297/cpe.28.1. Epub 2019 Jan 31.


Japanese patient with Cole-carpenter syndrome with compound heterozygous variants of SEC24D.

Takeyari S, Kubota T, Miyata K, Yamamoto K, Nakayama H, Yamamoto K, Ohata Y, Kitaoka T, Yanagi K, Kaname T, Ozono K.

Am J Med Genet A. 2018 Dec;176(12):2882-2886. doi: 10.1002/ajmg.a.40643. Epub 2018 Nov 21.


Functional analysis of monocarboxylate transporter 8 mutations in Japanese Allan-Herndon-Dudley syndrome patients.

Islam MS, Namba N, Ohata Y, Fujiwara M, Nakano C, Takeyari S, Miyata K, Nakano Y, Yamamoto K, Nakayama H, Kitaoka T, Kubota T, Ozono K.

Endocr J. 2019 Jan 28;66(1):19-29. doi: 10.1507/endocrj.EJ18-0251. Epub 2018 Oct 25.


The efficacy and safety of dydrogesterone for treatment of dysmenorrhea: An open-label multicenter clinical study.

Taniguchi F, Ota I, Iba Y, Toda T, Tagashira Y, Ohata Y, Kurioka H, Endo Y, Sunada H, Noma H, Azuma Y, Harada T.

J Obstet Gynaecol Res. 2019 Jan;45(1):168-175. doi: 10.1111/jog.13807. Epub 2018 Sep 23.


Alkylsulfanyl analogs as potent α2δ ligands.

Shimada K, Ohata Y, Kobayashi J, Onishi Y, Kawamura A, Domon Y, Arakawa N, Inoue T, Kitano Y, Matsuda F, Abe Y, Deguchi T.

Bioorg Med Chem Lett. 2018 Jun 15;28(11):2000-2002. doi: 10.1016/j.bmcl.2018.05.006. Epub 2018 May 4.


Assembling silicon quantum dots into wires, networks and rods via metal ion bridges.

Ohata Y, Sugimoto H, Fujii M.

Nanoscale. 2018 Apr 26;10(16):7597-7604. doi: 10.1039/c8nr00631h.


A lesion categorized between ghost cell odontogenic carcinoma and dentinogenic ghost cell tumor with CTNNB1 mutation.

Ohata Y, Kayamori K, Yukimori A, Sumikura K, Ohsako T, Harada H, Sakamoto K, Ikeda T.

Pathol Int. 2018 May;68(5):307-312. doi: 10.1111/pin.12659. Epub 2018 Mar 25.


Leukemia inhibitory factor produced by fibroblasts within tumor stroma participates in invasion of oral squamous cell carcinoma.

Ohata Y, Tsuchiya M, Hirai H, Yamaguchi S, Akashi T, Sakamoto K, Yamaguchi A, Ikeda T, Kayamori K.

PLoS One. 2018 Feb 14;13(2):e0191865. doi: 10.1371/journal.pone.0191865. eCollection 2018.


[Neoadjuvant Chemoradiotherapy for Locally Advanced Carcinoma Associated with Anal Fistula].

Miyakawa T, Iida S, Igaki T, Shiobara H, Matsumoto R, Mitachi K, Ohata Y, Saito K, Miura T, Irie T, Yamazaki S.

Gan To Kagaku Ryoho. 2017 Nov;44(12):1437-1439. Japanese.


A distinctive subgroup of oral EBV+ B-cell neoplasm with polymorphous features is potentially identical to EBV+ mucocutaneous ulcer.

Ohata Y, Tatsuzawa A, Ohyama Y, Ichikawa A, Mochizuki Y, Ishibashi S, Itakura Y, Sakurai U, Sakamoto K, Ikeda T, Kitagawa M, Yamamoto K.

Hum Pathol. 2017 Nov;69:129-139. doi: 10.1016/j.humpath.2017.09.013. Epub 2017 Oct 6.


Endocrinological and phenotype evaluation in a patient with acrodysostosis.

Ueyama K, Namba N, Kitaoka T, Yamamoto K, Fujiwara M, Ohata Y, Kubota T, Ozono K.

Clin Pediatr Endocrinol. 2017;26(3):177-182. doi: 10.1297/cpe.26.177. Epub 2017 Jul 27.


A modular synthesis approach to multinuclear heterometallic oxo clusters in polyoxometalates.

Minato T, Suzuki K, Ohata Y, Yamaguchi K, Mizuno N.

Chem Commun (Camb). 2017 Jul 4;53(54):7533-7536. doi: 10.1039/c7cc04072e.


Acquired Resistance with Epigenetic Alterations Under Long-Term Antiangiogenic Therapy for Hepatocellular Carcinoma.

Ohata Y, Shimada S, Akiyama Y, Mogushi K, Nakao K, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Arii S, Tanabe M, Tanaka S.

Mol Cancer Ther. 2017 Jun;16(6):1155-1165. doi: 10.1158/1535-7163.MCT-16-0728. Epub 2017 Feb 28.


[Malignant Pleural Mesothelioma with Excessive Inflammation and High Level of Interleukin 6 - A Case Report].

Miura T, Iida S, Igaki T, Shiobara H, Matsumoto R, Mitachi K, Miyakawa T, Ohata Y, Saitou K, Irie T, Yamazaki S.

Gan To Kagaku Ryoho. 2016 Nov;43(12):2106-2108. Japanese.


Effect of basal insulin therapy on vascular endothelial function and adipokine profiles in people with Type 2 diabetes.

Makino H, Tanaka A, Hosoda H, Koezuka R, Tochiya M, Ohata Y, Tamanaha T, Miyamoto Y, Kangawa K, Kishimoto I.

Diabet Med. 2016 Dec;33(12):1737-1743. doi: 10.1111/dme.13151. Epub 2016 May 30.


NOTCH3 Is Induced in Cancer-Associated Fibroblasts and Promotes Angiogenesis in Oral Squamous Cell Carcinoma.

Kayamori K, Katsube K, Sakamoto K, Ohyama Y, Hirai H, Yukimori A, Ohata Y, Akashi T, Saitoh M, Harada K, Harada H, Yamaguchi A.

PLoS One. 2016 Apr 28;11(4):e0154112. doi: 10.1371/journal.pone.0154112. eCollection 2016.


Fate of Escherichia coli O157 Cells Inoculated into Lightly Pickled Chinese Cabbage during Processing, Storage and Incubation in Artificial Gastric Juice.

Inatsu Y, Ohata Y, Ananchaipattana C, Latiful Bari M, Hosotani Y, Kawasaki S.

Biocontrol Sci. 2016;21(1):51-6. doi: 10.4265/bio.21.51.


Measles virus nucleocapsid protein increases osteoblast differentiation in Paget's disease.

Teramachi J, Nagata Y, Mohammad K, Inagaki Y, Ohata Y, Guise T, Michou L, Brown JP, Windle JJ, Kurihara N, Roodman GD.

J Clin Invest. 2016 Mar 1;126(3):1012-22. doi: 10.1172/JCI82012. Epub 2016 Feb 15.


Current concepts in perinatal mineral metabolism.

Ohata Y, Ozono K, Michigami T.

Clin Pediatr Endocrinol. 2016 Jan;25(1):9-17. doi: 10.1297/cpe.25.9. Epub 2016 Jan 30.


Successful induction of sclerostin in human-derived fibroblasts by 4 transcription factors and its regulation by parathyroid hormone, hypoxia, and prostaglandin E2.

Fujiwara M, Kubota T, Wang W, Ohata Y, Miura K, Kitaoka T, Okuzaki D, Namba N, Michigami T, Kitabatake Y, Ozono K.

Bone. 2016 Apr;85:91-8. doi: 10.1016/j.bone.2016.01.024. Epub 2016 Feb 2.


Serum NT-proCNP levels increased after initiation of GH treatment in patients with achondroplasia/hypochondroplasia.

Kubota T, Wang W, Miura K, Nakayama H, Yamamoto K, Fujiwara M, Ohata Y, Tachibana M, Kitaoka T, Takakuwa S, Miyoshi Y, Namba N, Ozono K.

Clin Endocrinol (Oxf). 2016 Jun;84(6):845-50. doi: 10.1111/cen.13025. Epub 2016 Feb 25.


Survival of Inoculated Escherichia coli O157:H7 in Japanese Sweet Dumplings during Storage.

Inatsu Y, Ohata Y, Nakamura N, Hosotani Y, Ananchaipattana C, Bari ML, Kawasaki S.

Biocontrol Sci. 2015;20(4):285-90. doi: 10.4265/bio.20.285.


Pharmacokinetic evaluation of liposomal amphotericin B (L-AMB) in patients with invasive fungal infection: Population approach in Japanese pediatrics.

Ohata Y, Tomita Y, Suzuki K, Maniwa T, Yano Y, Sunakawa K.

Drug Metab Pharmacokinet. 2015 Dec;30(6):400-9. doi: 10.1016/j.dmpk.2015.08.003. Epub 2015 Aug 28.


Acromesomelic dysplasia, type maroteaux caused by novel loss-of-function mutations of the NPR2 gene: Three case reports.

Wang W, Song MH, Miura K, Fujiwara M, Nawa N, Ohata Y, Kitaoka T, Kubota T, Namba N, Jin DK, Kim OH, Ozono K, Cho TJ.

Am J Med Genet A. 2016 Feb;170A(2):426-434. doi: 10.1002/ajmg.a.37463. Epub 2015 Nov 14.


Intensity of statin therapy and new hospitalizations for heart failure in patients with type 2 diabetes.

Kishimoto I, Makino H, Ohata Y, Tamanaha T, Tochiya M, Anzai T, Kusano K, Noguchi T, Yasuda S, Ogawa H.

BMJ Open Diabetes Res Care. 2015 Oct 29;3(1):e000137. doi: 10.1136/bmjdrc-2015-000137. eCollection 2015.


Impact of B-type natriuretic peptide (BNP) on development of atrial fibrillation in people with Type 2 diabetes.

Kishimoto I, Makino H, Ohata Y, Tamanaha T, Tochiya M, Kusano K, Anzai T, Toyoda K, Yasuda S, Minematsu K, Ogawa H.

Diabet Med. 2016 Aug;33(8):1118-24. doi: 10.1111/dme.12856. Epub 2015 Aug 18.


A Case of Odontogenic Infection by Streptococcus constellatus Leading to Systemic Infection in a Cogan's Syndrome Patient.

Abe M, Mori Y, Inaki R, Ohata Y, Abe T, Saijo H, Ohkubo K, Hoshi K, Takato T.

Case Rep Dent. 2014;2014:793174. doi: 10.1155/2014/793174. Epub 2014 Nov 20.


Anomalous enhancement of proton conductivity for water molecular clusters stabilized in interstitial spaces of porous molecular crystals.

Tadokoro M, Ohata Y, Ohhata Y, Shimazaki Y, Ishimaru S, Yamada T, Nagao Y, Sugaya T, Isoda K, Suzuki Y, Kitagawa H, Matsui H.

Chemistry. 2014 Oct 13;20(42):13698-709. doi: 10.1002/chem.201402900. Epub 2014 Sep 3. Erratum in: Chemistry. 2019 May 10;25(27):6847. Ohhata Y [corrected to Ohata Y].


Sirtuin inhibitor Ex-527 causes neural tube defects, ventral edema formations, and gastrointestinal malformations in Xenopus laevis embryos.

Ohata Y, Matsukawa S, Moriyama Y, Michiue T, Morimoto K, Sato Y, Kuroda H.

Dev Growth Differ. 2014 Aug;56(6):460-8. doi: 10.1111/dgd.12145. Epub 2014 Aug 5.


Interleukin-1-induced acute bone resorption facilitates the secretion of fibroblast growth factor 23 into the circulation.

Yamazaki M, Kawai M, Miyagawa K, Ohata Y, Tachikawa K, Kinoshita S, Nishino J, Ozono K, Michigami T.

J Bone Miner Metab. 2015 May;33(3):342-54. doi: 10.1007/s00774-014-0598-2. Epub 2014 Jul 5.


Spinal arteriovenous metameric syndrome in a neonate presenting with congestive heart failure: case report.

Komiyama M, Ishiguro T, Terada A, Watanabe Y, Nakajima H, Ohata Y, Matsusaka Y.

Childs Nerv Syst. 2014 Sep;30(9):1607-11. doi: 10.1007/s00381-014-2439-y. Epub 2014 May 21.


Dysregulated gene expression in the primary osteoblasts and osteocytes isolated from hypophosphatemic Hyp mice.

Miyagawa K, Yamazaki M, Kawai M, Nishino J, Koshimizu T, Ohata Y, Tachikawa K, Mikuni-Takagaki Y, Kogo M, Ozono K, Michigami T.

PLoS One. 2014 Apr 7;9(4):e93840. doi: 10.1371/journal.pone.0093840. eCollection 2014.


[Bone and Stem Cells. The mechanism of osteogenic differentiation from mesenchymal stem cell].

Ohata Y, Ozono K.

Clin Calcium. 2014 Apr;24(4):501-8. doi: CliCa1404501508. Review. Japanese.


Hemoglobin A1c predicts heart failure hospitalization independent of baseline cardiac function or B-type natriuretic peptide level.

Kishimoto I, Makino H, Ohata Y, Tamanaha T, Tochiya M, Kada A, Ishihara M, Anzai T, Shimizu W, Yasuda S, Ogawa H.

Diabetes Res Clin Pract. 2014 May;104(2):257-65. doi: 10.1016/j.diabres.2014.02.009. Epub 2014 Feb 20.


Two-dimensional materials as emulsion stabilizers: interfacial thermodynamics and molecular barrier properties.

Creighton MA, Ohata Y, Miyawaki J, Bose A, Hurt RH.

Langmuir. 2014 Apr 8;30(13):3687-96. doi: 10.1021/la500216n. Epub 2014 Mar 25.


Serum fibroblast growth factor 23 is a useful marker to distinguish vitamin D-deficient rickets from hypophosphatemic rickets.

Kubota T, Kitaoka T, Miura K, Fujiwara M, Ohata Y, Miyoshi Y, Yamamoto K, Takeyari S, Yamamoto T, Namba N, Ozono K.

Horm Res Paediatr. 2014;81(4):251-7. doi: 10.1159/000357142. Epub 2014 Feb 26.


Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice.

Ohata Y, Yamazaki M, Kawai M, Tsugawa N, Tachikawa K, Koinuma T, Miyagawa K, Kimoto A, Nakayama M, Namba N, Yamamoto H, Okano T, Ozono K, Michigami T.

J Bone Miner Res. 2014 Jul;29(7):1627-38. doi: 10.1002/jbmr.2186.


Two Japanese familial cases of Caffey disease with and without the common COL1A1 mutation and normal bone density, and review of the literature.

Kitaoka T, Miyoshi Y, Namba N, Miura K, Kubota T, Ohata Y, Fujiwara M, Takagi M, Hasegawa T, Jüppner H, Ozono K.

Eur J Pediatr. 2014 Jun;173(6):799-804. doi: 10.1007/s00431-013-2252-8. Epub 2014 Jan 4. Review.


[Updates on rickets and osteomalacia: guidelines for diagnosis of rickets and osteomalacia].

Ohata Y, Ozono K.

Clin Calcium. 2013 Oct;23(10):1421-8. doi: CliCa131014211428. Review. Japanese.


Structure-based gene targeting discovery of sphaerimicin, a bacterial translocase I inhibitor.

Funabashi M, Baba S, Takatsu T, Kizuka M, Ohata Y, Tanaka M, Nonaka K, Spork AP, Ducho C, Chen WC, Van Lanen SG.

Angew Chem Int Ed Engl. 2013 Oct 25;52(44):11607-11. doi: 10.1002/anie.201305546. Epub 2013 Sep 6.


Renal insufficiency without albuminuria is associated with peripheral artery atherosclerosis and lipid metabolism disorders in patients with type 2 diabetes.

Yamashita T, Makino H, Nakatani R, Ohata Y, Miyamoto Y, Kishimoto I.

J Atheroscler Thromb. 2013;20(11):790-7. Epub 2013 Jul 25.


Pediatric aspects of skeletal dysplasia.

Ozono K, Namba N, Kubota T, Kitaoka T, Miura K, Ohata Y, Fujiwara M, Miyoshi Y, Michigami T.

Pediatr Endocrinol Rev. 2012 Oct;10 Suppl 1:35-43. Review.


Proteomic analysis of the lung in rats with hypobaric hypoxia-induced pulmonary hypertension.

Ohata Y, Ogata S, Nakanishi K, Kanazawa F, Uenoyama M, Hiroi S, Tominaga S, Toda T, Kawai T.

Histol Histopathol. 2013 Jul;28(7):893-902. doi: 10.14670/HH-28.893. Epub 2013 Jan 10.


FGF23 suppresses chondrocyte proliferation in the presence of soluble α-Klotho both in vitro and in vivo.

Kawai M, Kinoshita S, Kimoto A, Hasegawa Y, Miyagawa K, Yamazaki M, Ohata Y, Ozono K, Michigami T.

J Biol Chem. 2013 Jan 25;288(4):2414-27. doi: 10.1074/jbc.M112.410043. Epub 2012 Dec 12.


An overgrowth disorder associated with excessive production of cGMP due to a gain-of-function mutation of the natriuretic peptide receptor 2 gene.

Miura K, Namba N, Fujiwara M, Ohata Y, Ishida H, Kitaoka T, Kubota T, Hirai H, Higuchi C, Tsumaki N, Yoshikawa H, Sakai N, Michigami T, Ozono K.

PLoS One. 2012;7(8):e42180. doi: 10.1371/journal.pone.0042180. Epub 2012 Aug 3.


Pre-melting structure transformation of water clusters in nanoporous molecular crystals.

Tadokoro M, Ohata Y, Shimazaki Y, Isoda K, Sugaya T.

Chemphyschem. 2012 Oct 8;13(14):3267-70. doi: 10.1002/cphc.201200414. Epub 2012 Jul 18. No abstract available.


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