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Items: 45

1.

Proton pump inhibitor use increases the risk of peritonitis in peritoneal dialysis patients.

Maeda S, Yamaguchi M, Maeda K, Kobayashi N, Izumi N, Nagai M, Obayashi T, Ohashi W, Katsuno T, Nobata H, Ito Y.

PLoS One. 2019 Nov 7;14(11):e0224859. doi: 10.1371/journal.pone.0224859. eCollection 2019.

2.

Internet survey on the actual situation of constipation in the Japanese population under 70 years old: focus on functional constipation and constipation-predominant irritable bowel syndrome.

Kawamura Y, Yamamoto S, Funaki Y, Ohashi W, Yamamoto K, Ozeki T, Yamaguchi Y, Tamura Y, Izawa S, Hijikata Y, Ebi M, Ogasawara N, Sasaki M, Kasugai K.

J Gastroenterol. 2019 Aug 19. doi: 10.1007/s00535-019-01611-8. [Epub ahead of print]

PMID:
31428873
3.

Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis.

Nishida K, Hasegawa A, Yamasaki S, Uchida R, Ohashi W, Kurashima Y, Kunisawa J, Kimura S, Iwanaga T, Watarai H, Hase K, Ogura H, Nakayama M, Kashiwakura JI, Okayama Y, Kubo M, Ohara O, Kiyono H, Koseki H, Murakami M, Hirano T.

Sci Rep. 2019 Jul 25;9(1):10842. doi: 10.1038/s41598-019-47132-5.

4.

The SOFA score could predict the severity and prognosis of infective endocarditis.

Asai N, Shiota A, Ohashi W, Watanabe H, Shibata Y, Kato H, Sakanashi D, Hagihara M, Koizumi Y, Yamagishi Y, Suematsu H, Mikamo H.

J Infect Chemother. 2019 Dec;25(12):965-971. doi: 10.1016/j.jiac.2019.05.014. Epub 2019 Jul 15.

PMID:
31320197
5.

Contribution of Zinc and Zinc Transporters in the Pathogenesis of Inflammatory Bowel Diseases.

Ohashi W, Fukada T.

J Immunol Res. 2019 Mar 10;2019:8396878. doi: 10.1155/2019/8396878. eCollection 2019. Review.

6.

Maintenance of Intestinal Epithelial Homeostasis by Zinc Transporters.

Ohashi W, Hara T, Takagishi T, Hase K, Fukada T.

Dig Dis Sci. 2019 Sep;64(9):2404-2415. doi: 10.1007/s10620-019-05561-2. Epub 2019 Mar 4. Review.

PMID:
30830525
7.

Regulatory Role of GRK2 in the TLR Signaling-Mediated iNOS Induction Pathway in Microglial Cells.

Palikhe S, Ohashi W, Sakamoto T, Hattori K, Kawakami M, Andoh T, Yamazaki H, Hattori Y.

Front Pharmacol. 2019 Feb 4;10:59. doi: 10.3389/fphar.2019.00059. eCollection 2019.

8.

Anti-inflammatory properties of cilostazol: Its interruption of DNA binding activity of NF-κB from the Toll-like receptor signaling pathways.

Sakamoto T, Ohashi W, Tomita K, Hattori K, Matsuda N, Hattori Y.

Int Immunopharmacol. 2018 Sep;62:120-131. doi: 10.1016/j.intimp.2018.06.021. Epub 2018 Jul 10.

PMID:
30005227
9.

Role of G protein-coupled receptor kinase 2 in oxidative and nitrosative stress-related neurohistopathological changes in a mouse model of sepsis-associated encephalopathy.

Kawakami M, Hattori M, Ohashi W, Fujimori T, Hattori K, Takebe M, Tomita K, Yokoo H, Matsuda N, Yamazaki M, Hattori Y.

J Neurochem. 2018 Jun;145(6):474-488. doi: 10.1111/jnc.14329. Epub 2018 May 16.

10.

Activator Protein-1 Decoy Oligodeoxynucleotide Transfection Is Beneficial in Reducing Organ Injury and Mortality in Septic Mice.

Imaizumi T, Matsuda N, Tomita K, Palikhe S, Ohashi W, Hattori K, Hattori Y.

Crit Care Med. 2018 May;46(5):e435-e442. doi: 10.1097/CCM.0000000000003009.

PMID:
29406423
11.

SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex.

Ohashi W, Yamamine N, Imura J, Hattori Y.

Biochem Biophys Res Commun. 2017 Nov 25;493(3):1342-1348. doi: 10.1016/j.bbrc.2017.09.161. Epub 2017 Sep 29.

PMID:
28970068
12.

Prostacyclin mimetics afford protection against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.

Misawa H, Ohashi W, Tomita K, Hattori K, Shimada Y, Hattori Y.

Toxicol Appl Pharmacol. 2017 Nov 1;334:55-65. doi: 10.1016/j.taap.2017.09.003. Epub 2017 Sep 5.

PMID:
28887131
13.

Different effect of resveratrol to induction of apoptosis depending on the type of human cancer cells.

Takashina M, Inoue S, Tomihara K, Tomita K, Hattori K, Zhao QL, Suzuki T, Noguchi M, Ohashi W, Hattori Y.

Int J Oncol. 2017 Mar;50(3):787-797. doi: 10.3892/ijo.2017.3859. Epub 2017 Jan 24.

PMID:
28197625
14.

Evaluation of the Surgical Device and Procedure for Extracellular Matrix-Scaffold-Supported Human iPSC-Derived Retinal Pigment Epithelium Cell Sheet Transplantation.

Kamao H, Mandai M, Ohashi W, Hirami Y, Kurimoto Y, Kiryu J, Takahashi M.

Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):211-220. doi: 10.1167/iovs.16-19778.

PMID:
28114582
15.

Critical role of endogenous histamine in promoting end-organ tissue injury in sepsis.

Hattori M, Yamazaki M, Ohashi W, Tanaka S, Hattori K, Todoroki K, Fujimori T, Ohtsu H, Matsuda N, Hattori Y.

Intensive Care Med Exp. 2016 Dec;4(1):36. Epub 2016 Nov 8.

16.

Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress.

Ohashi W, Kimura S, Iwanaga T, Furusawa Y, Irié T, Izumi H, Watanabe T, Hijikata A, Hara T, Ohara O, Koseki H, Sato T, Robine S, Mori H, Hattori Y, Watarai H, Mishima K, Ohno H, Hase K, Fukada T.

PLoS Genet. 2016 Oct 13;12(10):e1006349. doi: 10.1371/journal.pgen.1006349. eCollection 2016 Oct.

17.

Anti-Inflammatory Profile of Levosimendan in Cecal Ligation-Induced Septic Mice and in Lipopolysaccharide-Stimulated Macrophages.

Wang Q, Yokoo H, Takashina M, Sakata K, Ohashi W, Abedelzaher LA, Imaizumi T, Sakamoto T, Hattori K, Matsuda N, Hattori Y.

Crit Care Med. 2015 Nov;43(11):e508-20. doi: 10.1097/CCM.0000000000001269.

PMID:
26468714
18.

Control of Macrophage Dynamics as a Potential Therapeutic Approach for Clinical Disorders Involving Chronic Inflammation.

Ohashi W, Hattori K, Hattori Y.

J Pharmacol Exp Ther. 2015 Sep;354(3):240-50. doi: 10.1124/jpet.115.225540. Epub 2015 Jul 1. Review.

PMID:
26136420
19.

Anti-M Antibody Induced Prolonged Anemia Following Hemolytic Disease of the Newborn Due to Erythropoietic Suppression in 2 Siblings.

Ishida A, Ohto H, Yasuda H, Negishi Y, Tsuiki H, Arakawa T, Yagi Y, Uchimura D, Miyazaki T, Ohashi W, Takamoto S.

J Pediatr Hematol Oncol. 2015 Aug;37(6):e375-7. doi: 10.1097/MPH.0000000000000341.

PMID:
25929611
20.

[GRK2 as a potential therapeutic target for septic ARDS].

Ohashi W, Hattori Y.

Nihon Yakurigaku Zasshi. 2015 Mar;145(3):122-8. doi: 10.1254/fpj.145.122. Japanese. No abstract available.

PMID:
25765493
21.

In vivo depletion of CD206+ M2 macrophages exaggerates lung injury in endotoxemic mice.

Kambara K, Ohashi W, Tomita K, Takashina M, Fujisaka S, Hayashi R, Mori H, Tobe K, Hattori Y.

Am J Pathol. 2015 Jan;185(1):162-71. doi: 10.1016/j.ajpath.2014.09.005. Epub 2014 Oct 27.

PMID:
25447055
22.

Cardiac fibroblasts: contributory role in septic cardiac dysfunction.

Tomita K, Takashina M, Mizuno N, Sakata K, Hattori K, Imura J, Ohashi W, Hattori Y.

J Surg Res. 2015 Feb;193(2):874-87. doi: 10.1016/j.jss.2014.09.012. Epub 2014 Sep 16.

PMID:
25291964
23.

Molecular pathogenesis of spondylocheirodysplastic Ehlers-Danlos syndrome caused by mutant ZIP13 proteins.

Bin BH, Hojyo S, Hosaka T, Bhin J, Kano H, Miyai T, Ikeda M, Kimura-Someya T, Shirouzu M, Cho EG, Fukue K, Kambe T, Ohashi W, Kim KH, Seo J, Choi DH, Nam YJ, Hwang D, Fukunaka A, Fujitani Y, Yokoyama S, Superti-Furga A, Ikegawa S, Lee TR, Fukada T.

EMBO Mol Med. 2014 Aug;6(8):1028-42. doi: 10.15252/emmm.201303809.

24.

Photo-triggered molecular release based on auto-degradable polymer-containing organic-inorganic hybrids.

Okada H, Tanaka K, Ohashi W, Chujo Y.

Bioorg Med Chem. 2014 Jul 1;22(13):3435-40. doi: 10.1016/j.bmc.2014.04.034. Epub 2014 Apr 28.

PMID:
24837155
25.

Tonic inhibition by G protein-coupled receptor kinase 2 of Akt/endothelial nitric-oxide synthase signaling in human vascular endothelial cells under conditions of hyperglycemia with high insulin levels.

Taguchi K, Sakata K, Ohashi W, Imaizumi T, Imura J, Hattori Y.

J Pharmacol Exp Ther. 2014 May;349(2):199-208. doi: 10.1124/jpet.113.211854. Epub 2014 Feb 25.

PMID:
24570070
26.

Hypoxic condition-selective upconversion via triplet-triplet annihilation based on POSS-core dendrimer complexes.

Tanaka K, Okada H, Ohashi W, Jeon JH, Inafuku K, Chujo Y.

Bioorg Med Chem. 2013 May 15;21(10):2678-81. doi: 10.1016/j.bmc.2013.03.029. Epub 2013 Mar 29.

PMID:
23582446
27.

A novel role of the L-type calcium channel α1D subunit as a gatekeeper for intracellular zinc signaling: zinc wave.

Yamasaki S, Hasegawa A, Hojyo S, Ohashi W, Fukada T, Nishida K, Hirano T.

PLoS One. 2012;7(6):e39654. doi: 10.1371/journal.pone.0039654. Epub 2012 Jun 22.

28.

Identification of amino acid residues essential for onion lachrymatory factor synthase activity.

Masamura N, Ohashi W, Tsuge N, Imai S, Ishii-Nakamura A, Hirota H, Nagata T, Kumagai H.

Biosci Biotechnol Biochem. 2012;76(3):447-53.

29.

Biochemical characterization of human ZIP13 protein: a homo-dimerized zinc transporter involved in the spondylocheiro dysplastic Ehlers-Danlos syndrome.

Bin BH, Fukada T, Hosaka T, Yamasaki S, Ohashi W, Hojyo S, Miyai T, Nishida K, Yokoyama S, Hirano T.

J Biol Chem. 2011 Nov 18;286(46):40255-65. doi: 10.1074/jbc.M111.256784. Epub 2011 Sep 14.

30.

The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth.

Hojyo S, Fukada T, Shimoda S, Ohashi W, Bin BH, Koseki H, Hirano T.

PLoS One. 2011 Mar 22;6(3):e18059. doi: 10.1371/journal.pone.0018059.

31.

Solution structure and fluctuation of the Mg(2+)-bound form of calmodulin C-terminal domain.

Ohashi W, Hirota H, Yamazaki T.

Protein Sci. 2011 Apr;20(4):690-701. doi: 10.1002/pro.598.

32.

Benefits of pharmacogenomics in drug development-earlier launch of drugs and less adverse events.

Ohashi W, Tanaka H.

J Med Syst. 2010 Aug;34(4):701-7. doi: 10.1007/s10916-009-9284-7. Epub 2009 Apr 9.

PMID:
20703925
33.

Zinc suppresses Th17 development via inhibition of STAT3 activation.

Kitabayashi C, Fukada T, Kanamoto M, Ohashi W, Hojyo S, Atsumi T, Ueda N, Azuma I, Hirota H, Murakami M, Hirano T.

Int Immunol. 2010 May;22(5):375-86. doi: 10.1093/intimm/dxq017. Epub 2010 Mar 9.

PMID:
20215335
34.

Intensity of chronic cerebral hypoperfusion determines white/gray matter injury and cognitive/motor dysfunction in mice.

Miki K, Ishibashi S, Sun L, Xu H, Ohashi W, Kuroiwa T, Mizusawa H.

J Neurosci Res. 2009 Apr;87(5):1270-81. doi: 10.1002/jnr.21925.

PMID:
18951530
35.

Pharmacogenetics of hormone replacement therapy for climacteric symptoms.

Takeo C, Ugai K, Araki J, Zhang L, Baba M, Ohashi W, Ueno K, Suzuki Y, Amano K, Hirai A, Muramatsu M.

Biochem Biophys Res Commun. 2008 Oct 3;374(4):604-8. doi: 10.1016/j.bbrc.2008.07.017. Epub 2008 Jul 15.

PMID:
18627768
36.

Economic advantage of pharmacogenomics - clinical trials with genetic information.

Ohashi W, Mizushima H, Tanaka H.

Stud Health Technol Inform. 2008;136:585-90.

PMID:
18487794
37.

Generation of a monoclonal antibody specific for tissue-nonspecific alkaline phosphatase and its use in a clinical diagnostic study.

Ohashi T, Sunaga M, Miura T, Sasagawa K, Sato Y, Ohashi W, Katagiri K, Katano Y, Kiyokawa I, Kojima R, Tomonaga T, Nomura F, Amizuka N, Oda K, Sato T, Katayama K.

Hybridoma (Larchmt). 2007 Dec;26(6):401-6.

PMID:
18158785
38.

[The mechanism of TRACP 5b maturation].

Ohashi T, Ichimura S, Mochizuki Y, Miura T, Mogushi K, Ohashi W, Sato Y, Kojima R, Tanaka H, Igarashi Y, Nomura F, Katayama K, Miki T, Nishizawa Y.

Rinsho Byori. 2007 Apr;55(4):325-9. Japanese.

PMID:
17511262
39.

NMR analysis of the Mg2+-binding properties of aequorin, a Ca2+-binding photoprotein.

Ohashi W, Inouye S, Yamazaki T, Hirota H.

J Biochem. 2005 Nov;138(5):613-20.

PMID:
16272573
40.

Backbone 1H, 13C and 15N resonance assignments for the Mg2+-bound form of the Ca2+-binding photoprotein aequorin.

Ohashi W, Inouye S, Yamazaki T, Doi-Katayama Y, Yokoyama S, Hirota H.

J Biomol NMR. 2005 Apr;31(4):375-6. No abstract available.

PMID:
15929011
41.

Topological stability and self-association of a completely hydrophobic model transmembrane helix in lipid bilayers.

Yano Y, Takemoto T, Kobayashi S, Yasui H, Sakurai H, Ohashi W, Niwa M, Futaki S, Sugiura Y, Matsuzaki K.

Biochemistry. 2002 Mar 5;41(9):3073-80.

PMID:
11863446
42.

Stearylated arginine-rich peptides: a new class of transfection systems.

Futaki S, Ohashi W, Suzuki T, Niwa M, Tanaka S, Ueda K, Harashima H, Sugiura Y.

Bioconjug Chem. 2001 Nov-Dec;12(6):1005-11.

PMID:
11716693
43.

Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery.

Futaki S, Suzuki T, Ohashi W, Yagami T, Tanaka S, Ueda K, Sugiura Y.

J Biol Chem. 2001 Feb 23;276(8):5836-40. Epub 2000 Nov 17.

44.

[Bilateral visual function in hemi-aphakia].

Ohashi W, Ikeyama K.

Ganka. 1970 Jun;12(6):486-91. Japanese. No abstract available.

PMID:
5464982
45.

[ON THE TREATMENT OF RESISTANT DYSENTERY WITH A COMBINATION OF KANAMYCIN AND CHLORAMPHENICOL (KANAPHENICOL)].

OHASHI W, AISAKA T, HIROHATA N, TSUJI T, HASHIMOTO H.

Nihon Densenbyo Gakkai Zasshi. 1963 Aug;37:174-80. Japanese. No abstract available.

PMID:
14059602

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