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Items: 1 to 50 of 1981

1.

Re-administration of osimertinib in osimertinib-acquired resistant non-small-cell lung cancer.

Ichihara E, Hotta K, Ninomiya K, Kubo T, Ohashi K, Rai K, Tanaka H, Tabata M, Maeda Y, Kiura K.

Lung Cancer. 2019 Jun;132:54-58. doi: 10.1016/j.lungcan.2019.02.021. Epub 2019 Apr 6.

PMID:
31097094
2.

The effect and safety of immune checkpoint inhibitor rechallenge in non-small cell lung cancer.

Watanabe H, Kubo T, Ninomiya K, Kudo K, Minami D, Murakami E, Ochi N, Ninomiya T, Harada D, Yasugi M, Ichihara E, Ohashi K, Fujiwara K, Hotta K, Tabata M, Maeda Y, Kiura K.

Jpn J Clin Oncol. 2019 May 15. pii: hyz066. doi: 10.1093/jjco/hyz066. [Epub ahead of print]

PMID:
31090906
3.

A consideration for efficient unrelated hematopoietic stem cell source acquisition-from an experience of Japan.

Nishiwaki S, Miyamura K, Kanda Y, Takanashi M, Uchida N, Fukuda T, Ikegame K, Ohashi K, Eto T, Ozawa Y, Shiratori S, Iwato K, Matsuoka KI, Hidaka M, Ichinohe T, Atsuta Y, Kodera Y, Okamoto S.

Bone Marrow Transplant. 2019 May 14. doi: 10.1038/s41409-019-0542-0. [Epub ahead of print] No abstract available.

PMID:
31089273
4.

A Prospective Cohort Study to Define the Clinical Features and Outcome of Lung Cancers Harboring HER2 Aberration in Japan (HER2-CS STUDY).

Ninomiya K, Hata T, Yoshioka H, Ohashi K, Bessho A, Hosokawa S, Ishikawa N, Yamasaki M, Shibayama T, Aoe K, Kozuki T, Harita S, Ueda Y, Murakami T, Fujimoto N, Yanai H, Toyooka S, Takata M, Hotta K, Kiura K; HER2-CS Network.

Chest. 2019 May 6. pii: S0012-3692(19)30031-5. doi: 10.1016/j.chest.2019.01.011. [Epub ahead of print]

PMID:
31072612
5.

[Transfusion-associated circulatory overload with pulmonary alveolar hemorrhage following allogeneic bone marrow transplantation].

Adachi H, Doki N, Hino Y, Senoo Y, Ikegawa S, Watanabe D, Inamoto K, Yoshioka K, Najima Y, Kobayashi T, Kakihana K, Haraguchi K, Kitahara Y, Okuyama Y, Sakamaki H, Ohashi K.

Rinsho Ketsueki. 2019;60(4):296-301. doi: 10.11406/rinketsu.60.296. Japanese.

PMID:
31068559
6.

Induced Pluripotent Stem Cell Derivation and Ex Vivo Gene Correction Using a Mucopolysaccharidosis Type 1 Disease Mouse Model.

Miki T, Vazquez L, Yanuaria L, Lopez O, Garcia IM, Ohashi K, Rodriguez NS.

Stem Cells Int. 2019 Apr 1;2019:6978303. doi: 10.1155/2019/6978303. eCollection 2019.

7.

Risk stratification and prognosticators of acute myeloid leukemia with myelodysplasia-related changes patients undergoing allogeneic stem cell transplantation: a retrospective study of the Adult Acute Myeloid Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation.

Harada K, Konuma T, Machida S, Mori J, Aoki J, Uchida N, Ohashi K, Fukuda T, Tanaka M, Ikegame K, Ozawa Y, Iwato K, Eto T, Onizuka M, Ichinohe T, Atsuta Y, Yano S.

Biol Blood Marrow Transplant. 2019 May 2. pii: S1083-8791(19)30272-1. doi: 10.1016/j.bbmt.2019.04.025. [Epub ahead of print]

PMID:
31054982
8.

NOD-like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastasis in NAFLD.

Ohashi K, Wang Z, Yang YM, Billet S, Tu W, Pimienta M, Cassel SL, Pandol SJ, Lu SC, Sutterwala FS, Bhowmick N, Seki E.

Hepatology. 2019 May 1. doi: 10.1002/hep.30693. [Epub ahead of print]

PMID:
31044438
9.

Quitting starts in the brain: a randomized controlled trial of app-based mindfulness shows decreases in neural responses to smoking cues that predict reductions in smoking.

Janes AC, Datko M, Roy A, Barton B, Druker S, Neal C, Ohashi K, Benoit H, van Lutterveld R, Brewer JA.

Neuropsychopharmacology. 2019 Apr 30. doi: 10.1038/s41386-019-0403-y. [Epub ahead of print]

PMID:
31039580
10.

Associations among circulating levels of follistatin-like 1, clinical parameters, and cardiovascular events in patients undergoing elective percutaneous coronary intervention with drug-eluting stents.

Aikawa T, Shimada K, Miyauchi K, Miyazaki T, Sai E, Ouchi S, Kadoguchi T, Kunimoto M, Joki Y, Dohi T, Okazaki S, Isoda K, Ohashi K, Murohara T, Ouchi N, Daida H.

PLoS One. 2019 Apr 29;14(4):e0216297. doi: 10.1371/journal.pone.0216297. eCollection 2019.

11.

Dietary vegetable intake is inversely associated with ATP-binding cassette protein A1 (ABCA1) DNA methylation levels among Japanese women.

Fujii R, Yamada H, Munetsuna E, Yamazaki M, Mizuno G, Tsuboi Y, Ohashi K, Ishikawa H, Ando Y, Hagiwara C, Maeda K, Hashimoto S, Hamajima N, Suzuki K.

Nutrition. 2019 Feb 23;65:1-5. doi: 10.1016/j.nut.2019.02.010. [Epub ahead of print]

PMID:
31029915
12.

Clinical impact of the gap-angle ratio in patients with ostial lesions of the right coronary artery undergoing percutaneous coronary intervention.

Ohashi K, Abe D, Kuroki N, Yuba T, Suzuki K.

Heart Vessels. 2019 Apr 26. doi: 10.1007/s00380-019-01417-x. [Epub ahead of print]

PMID:
31028408
13.

Author Correction: A missense mutation in the HECT domain of NEDD4L identified in a girl with periventricular nodular heterotopia, polymicrogyria, and cleft palate.

Kato K, Miya F, Hori I, Ieda D, Ohashi K, Negishi Y, Hattori A, Okamoto N, Kato M, Tsunoda T, Yamasaki M, Kanemura Y, Kosaki K, Saitoh S.

J Hum Genet. 2019 Apr 26. doi: 10.1038/s10038-019-0610-8. [Epub ahead of print]

PMID:
31028281
14.
15.

The Authors' Reply to "The Addition of Prophylactic Antibiotics Can Achieve a Favorable Outcome".

Kaito S, Sekiya N, Najima Y, Sano N, Horiguchi S, Kakihana K, Hishima T, Ohashi K.

Intern Med. 2019 Apr 17. doi: 10.2169/internalmedicine.2793-19. [Epub ahead of print] No abstract available.

16.

A Simple and Useful Predictive Assay for Evaluating the Quality of Isolated Hepatocytes for Hepatocyte Transplantation.

Matsumura M, Imura T, Inagaki A, Ogasawara H, Fukuoka K, Fathi I, Miyagi S, Ohashi K, Unno M, Kamei T, Satomi S, Goto M.

Sci Rep. 2019 Apr 16;9(1):6166. doi: 10.1038/s41598-019-42720-x.

17.

Successful hematopoietic stem-cell mobilization with plerixafor plus granulocyte-colony stimulating factor in multiple myeloma patients treated with pomalidomide.

Yoshifuji K, Toya T, Adachi H, Fujita M, Wada A, Konuma R, Kishida Y, Konishi T, Nagata A, Yamada Y, Kaito S, Kumagai T, Inamoto K, Akiyama M, Igarashi A, Najima Y, Doki N, Kobayashi T, Kakihana K, Sakamaki H, Ohashi K.

Int J Hematol. 2019 Apr 13. doi: 10.1007/s12185-019-02622-0. [Epub ahead of print]

PMID:
30989487
18.

Specific expression of MUC21 in micropapillary elements of lung adenocarcinomas - Implications for the progression of EGFR-mutated lung adenocarcinomas.

Matsumura M, Okudela K, Nakashima Y, Mitsui H, Denda-Nagai K, Suzuki T, Arai H, Umeda S, Tateishi Y, Koike C, Kataoka T, Irimura T, Ohashi K.

PLoS One. 2019 Apr 11;14(4):e0215237. doi: 10.1371/journal.pone.0215237. eCollection 2019.

19.

Better disease control before allogeneic stem cell transplantation is crucial to improve the outcomes of transplantation for acute myeloid leukemia patients with extramedullary disease.

Yamasaki S, Aoki J, Mori J, Mizuno S, Uchida N, Ohashi K, Fukuda T, Ikegame K, Eto T, Ogawa Y, Tanaka M, Hidaka M, Iwato K, Sawa M, Ichinohe T, Kanda Y, Atsuta Y, Yanada M, Yano S; Adult Acute Myeloid Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation.

Bone Marrow Transplant. 2019 Apr 10. doi: 10.1038/s41409-019-0527-z. [Epub ahead of print] No abstract available.

PMID:
30971777
20.

Assessing body dissatisfaction in Japanese women during the second trimester of pregnancy using a new figure rating scale.

Tsuchiya S, Yasui M, Ohashi K.

Nurs Health Sci. 2019 Apr 9. doi: 10.1111/nhs.12608. [Epub ahead of print]

PMID:
30968515
21.

Relationship between pre-sarcopenia and quality of life in patients with chronic liver disease: a cross-sectional study.

Ohashi K, Ishikawa T, Imai M, Suzuki M, Hoshii A, Abe H, Koyama F, Nakano T, Ueki A, Noguchi H, Hasegawa E, Hirosawa S, Kobayashi M, Hirosawa H, Sato K, Munakata M, Yoshida T.

Eur J Gastroenterol Hepatol. 2019 Apr 5. doi: 10.1097/MEG.0000000000001415. [Epub ahead of print]

PMID:
30964810
22.

Unique expression profiles of mucin proteins in interstitial pneumonia-associated lung adenocarcinomas.

Kataoka T, Okudela K, Nakashima Y, Mitsui H, Matsumura M, Umeda S, Arai H, Baba T, Suzuki T, Koike C, Tateishi Y, Tajiri M, Takemura T, Ogura T, Masuda M, Ohashi K.

Histol Histopathol. 2019 Apr 9:18114. doi: 10.14670/HH-18-114. [Epub ahead of print]

PMID:
30964151
23.

Outcomes of second allogeneic haematopoietic stem cell transplantation in patients with relapse of myelodysplastic syndrome.

Shimomura Y, Hara M, Tachibana T, Ohashi K, Sakura T, Fukuda T, Nakazawa H, Iwato K, Kanda Y, Ikeda T, Eto T, Kanda J, Ichinohe T, Atsuta Y, Ishikawa T, Ishiyama K.

Br J Haematol. 2019 Apr 2. doi: 10.1111/bjh.15898. [Epub ahead of print]

PMID:
30941758
24.

A phase I/II trial of weekly nab-paclitaxel for pretreated non-small-cell lung cancer patients without epidermal growth factor receptor mutations and anaplastic lymphoma kinase rearrangement.

Harada D, Kozuki T, Nogami N, Bessho A, Hosokawa S, Fukamatsu N, Hotta K, Ohashi K, Kubo T, Yoshioka H, Yokoyama T, Sone N, Kuyama S, Kudo K, Yasugi M, Takigawa N, Oze I, Kiura K.

Asia Pac J Clin Oncol. 2019 Apr 1. doi: 10.1111/ajco.13147. [Epub ahead of print]

PMID:
30938103
25.

A novel splicing mutation in SLC9A6 in a boy with Christianson syndrome.

Ieda D, Hori I, Nakamura Y, Ohashi K, Negishi Y, Hattori A, Arisaka A, Hasegawa S, Saitoh S.

Hum Genome Var. 2019 Mar 25;6:15. doi: 10.1038/s41439-019-0046-x. eCollection 2019.

26.

Single-centre retrospective observational study comparing trough blood concentration and safety of teicoplanin formulations.

Shinoda R, Shinoda Y, Ohashi K, Matsuoka T, Hirose T, Sugiyama T, Yoshimura T.

J Infect Chemother. 2019 Mar 28. pii: S1341-321X(18)30340-4. doi: 10.1016/j.jiac.2019.03.006. [Epub ahead of print]

PMID:
30929977
27.

Keratin-binding ability of the N-terminal Solo domain of Solo is critical for its function in cellular mechanotransduction.

Fujiwara S, Matsui TS, Ohashi K, Mizuno K, Deguchi S.

Genes Cells. 2019 May;24(5):390-402. doi: 10.1111/gtc.12682. Epub 2019 Apr 21.

PMID:
30929300
28.

Isolated adrenocorticotropic hormone deficiency and thyroiditis associated with nivolumab therapy in a patient with advanced lung adenocarcinoma: a case report and review of the literature.

Ohara N, Kobayashi M, Ohashi K, Ito R, Ikeda Y, Kawaguchi G, Yoneoka Y, Hasegawa G, Takada T.

J Med Case Rep. 2019 Mar 26;13(1):88. doi: 10.1186/s13256-019-2002-2.

29.

Associations of circulating microRNAs (miR-17, miR-21, and miR-150) and chronic kidney disease in a Japanese population.

Fujii R, Yamada H, Munetsuna E, Yamazaki M, Ohashi K, Ishikawa H, Maeda K, Hagiwara C, Ando Y, Hashimoto S, Hamajima N, Suzuki K.

J Epidemiol. 2019 Mar 23. doi: 10.2188/jea.JE20180233. [Epub ahead of print]

30.

Geriatric nutritional risk index (GNRI) just before allogeneic hematopoietic stem cell transplantation predicts transplant outcomes in patients older than 50 years with acute myeloid leukemia in complete remission.

Konishi T, Doki N, Kishida Y, Nagata A, Yamada Y, Kaito S, Kurosawa S, Yoshifuji K, Shirane S, Uchida T, Inamoto K, Toya T, Igarashi A, Najima Y, Kobayashi T, Kakihana K, Sakamaki H, Ohashi K.

Ann Hematol. 2019 Mar 21. doi: 10.1007/s00277-019-03668-0. [Epub ahead of print] No abstract available.

PMID:
30899981
31.

Carbohydrate Metabolic Compensation Coupled to High Tolerance to Oxidative Stress in Ticks.

Della Noce B, Carvalho Uhl MV, Machado J, Waltero CF, de Abreu LA, da Silva RM, da Fonseca RN, de Barros CM, Sabadin G, Konnai S, da Silva Vaz I Jr, Ohashi K, Logullo C.

Sci Rep. 2019 Mar 18;9(1):4753. doi: 10.1038/s41598-019-41036-0.

32.

Adipolin/CTRP12 protects against pathological vascular remodeling through suppression of smooth muscle cell growth and macrophage inflammatory response.

Ogawa H, Ohashi K, Ito M, Shibata R, Kanemura N, Yuasa D, Kambara T, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Otaka N, Kawanishi H, Yamaguchi S, Enomoto T, Abe T, Kaneko M, Takefuji M, Murohara T, Ouchi N.

Cardiovasc Res. 2019 Mar 15. pii: cvz074. doi: 10.1093/cvr/cvz074. [Epub ahead of print]

PMID:
30874788
33.

Maternal high-fructose intake increases circulating corticosterone levels via decreased adrenal corticosterone clearance in adult offspring.

Munetsuna E, Yamada H, Yamazaki M, Ando Y, Mizuno G, Hattori Y, Sadamoto N, Ishikawa H, Ohta Y, Fujii R, Suzuki K, Hashimoto S, Ohashi K.

J Nutr Biochem. 2019 May;67:44-50. doi: 10.1016/j.jnutbio.2019.01.016. Epub 2019 Feb 12.

PMID:
30856463
34.

Increased opportunity for prolonged survival after allogeneic hematopoietic stem cell transplantation in patients aged 60-69 years with myelodysplastic syndrome.

Itonaga H, Ishiyama K, Aoki K, Aoki J, Ishikawa T, Uchida N, Ohashi K, Ueda Y, Fukuda T, Sakura T, Ohno Y, Iwato K, Okumura H, Kondo T, Ichinohe T, Takanashi M, Atsuta Y, Miyazaki Y.

Ann Hematol. 2019 Jun;98(6):1367-1381. doi: 10.1007/s00277-019-03653-7. Epub 2019 Mar 11.

PMID:
30854574
35.

A subpopulation of airway epithelial cells that express hepatocyte nuclear factor 4α - its implication in the development of non-terminal respiratory unit-type lung adenocarcinoma.

Okudela K, Arai H, Kitamura H, Baba T, Mitsui H, Suzuki T, Sugiyama M, Honda E, Matsumura M, Takemura T, Kataoka T, Koike C, Tateshi Y, Tajiri M, Ogura T, Ohashi K.

Histol Histopathol. 2019 Mar 8:18098. doi: 10.14670/HH-18-098. [Epub ahead of print]

PMID:
30848476
36.

Effectiveness of pulmonary vasodilators on pulmonary hypertension associated with POEMS syndrome.

Ohashi K, Nishimura R, Sugimoto S, Sakao S, Tanabe N, Tatsumi K.

Respirol Case Rep. 2019 Feb 27;7(4):e00411. doi: 10.1002/rcr2.411. eCollection 2019 May.

37.

Nonproteinuric Versus Proteinuric Phenotypes in Diabetic Kidney Disease: A Propensity Score-Matched Analysis of a Nationwide, Biopsy-Based Cohort Study.

Yamanouchi M, Furuichi K, Hoshino J, Toyama T, Hara A, Shimizu M, Kinowaki K, Fujii T, Ohashi K, Yuzawa Y, Kitamura H, Suzuki Y, Sato H, Uesugi N, Hisano S, Ueda Y, Nishi S, Yokoyama H, Nishino T, Samejima K, Kohagura K, Shibagaki Y, Mise K, Makino H, Matsuo S, Ubara Y, Wada T; Research Group of Diabetic Nephropathy, the Ministry of Health, Labour and Welfare, and the Japan Agency for Medical Research and Development.

Diabetes Care. 2019 May;42(5):891-902. doi: 10.2337/dc18-1320. Epub 2019 Mar 4.

PMID:
30833372
38.

Comparison of Outcomes of Allogeneic Transplantation for Primary Myelofibrosis among Hematopoietic Stem Cell Source Groups.

Murata M, Takenaka K, Uchida N, Ozawa Y, Ohashi K, Kim SW, Ikegame K, Kanda Y, Kobayashi H, Ishikawa J, Ago H, Hirokawa M, Fukuda T, Atsuta Y, Kondo T.

Biol Blood Marrow Transplant. 2019 Mar 1. pii: S1083-8791(19)30144-2. doi: 10.1016/j.bbmt.2019.02.019. [Epub ahead of print]

PMID:
30826464
39.

Effects of bovine tumor necrosis factor alpha decoy receptors on cell death and inflammatory cytokine kinetics: potential for bovine inflammation therapy.

Fujisawa S, Konnai S, Okagawa T, Maekawa N, Tanaka A, Suzuki Y, Murata S, Ohashi K.

BMC Vet Res. 2019 Feb 28;15(1):68. doi: 10.1186/s12917-019-1813-0.

40.

Load-dependent detachment kinetics plays a key role in bidirectional cargo transport by kinesin and dynein.

Ohashi KG, Han L, Mentley B, Wang J, Fricks J, Hancock WO.

Traffic. 2019 Apr;20(4):284-294. doi: 10.1111/tra.12639.

PMID:
30809891
41.

Associations of serum microRNA-20a, -27a, and -103a with cognitive function in a Japanese population: The Yakumo study.

Kondo M, Yamada H, Munetsuna E, Yamazaki M, Hatta T, Iwahara A, Ohashi K, Ishikawa H, Tsuboi Y, Inoue T, Fujii R, Suzuki K.

Arch Gerontol Geriatr. 2019 May - Jun;82:155-160. doi: 10.1016/j.archger.2019.01.007. Epub 2019 Feb 8.

PMID:
30802839
42.

Chemoradiotherapy for locally advanced lung cancer patients with interstitial lung abnormalities.

Higo H, Kubo T, Makimoto S, Makimoto G, Ihara H, Masaoka Y, Ninomiya T, Ichihara E, Ohashi K, Sato A, Hotta K, Tabata M, Takigawa N, Maeda Y, Kiura K.

Jpn J Clin Oncol. 2019 Feb 22. pii: hyz016. doi: 10.1093/jjco/hyz016. [Epub ahead of print]

PMID:
30793176
43.

Management for H-type anorectal malformation with rectourethral and rectoscrotal fistula.

Hoshi R, Uehara S, Ono K, Ohashi K, Koshinaga T.

Pediatr Int. 2019 Mar;61(3):312-313. doi: 10.1111/ped.13770. Epub 2019 Feb 15. No abstract available.

PMID:
30767341
44.

[Efficacy and Safety of Gefitinib as First-Line Chemotherapy for Elderly Patients with Advanced Non-Small Cell Lung Cancer(NSCLC)].

Ohashi K, Takamori M, Takahashi Y, Kawai S, Yamamoto M, Kitazono M, Murata K, Wada A.

Gan To Kagaku Ryoho. 2019 Jan;46(1):55-59. Japanese.

PMID:
30765643
45.

Intestinal Failure-Associated Liver Disease and Eicosapentaenoic Acid/Arachidonic Acid Ratio.

Miura W, Nagano N, Kato R, Okahashi A, Yoshikawa K, Ohashi K, Koshinaga T, Morioka I.

Indian J Pediatr. 2019 Jun;86(6):548-550. doi: 10.1007/s12098-019-02895-7. Epub 2019 Feb 13.

PMID:
30761448
46.

High probability of follow-up termination among AYA survivors after allogeneic hematopoietic cell transplantation.

Miyamura K, Yamashita T, Atsuta Y, Ichinohe T, Kato K, Uchida N, Fukuda T, Ohashi K, Ogawa H, Eto T, Inoue M, Takahashi S, Mori T, Kanamori H, Yabe H, Hama A, Okamoto S, Inamoto Y.

Blood Adv. 2019 Feb 12;3(3):397-405. doi: 10.1182/bloodadvances.2018026039.

47.

Efficacy and Safety of a Weekly Cyclophosphamide-Bortezomib-Dexamethasone Regimen as Induction Therapy Prior to Autologous Stem Cell Transplantation in Japanese Patients with Newly Diagnosed Multiple Myeloma: A Phase 2 Multicenter Trial.

Tanaka K, Toyota S, Akiyama M, Wakimoto N, Nakamura Y, Najima Y, Doki N, Kakihana K, Igarashi A, Kobayashi T, Ohashi K, Kudo D, Shinagawa A, Takano H, Fujio T, Okoshi Y, Hori M, Kumagai T, Saito T, Mukae J, Yamamoto K, Tsutsumi I, Komeno T, Yoshida C, Yamamoto M, Kojima H; on behalf of the Ochanomizu Hematology Study Group.

Acta Haematol. 2019;141(2):111-118. doi: 10.1159/000495338. Epub 2019 Feb 6.

PMID:
30726834
48.

Clinical impact of the loss of chromosome 7q on outcomes of patients with myelodysplastic syndromes treated with allogeneic hematopoietic stem cell transplantation.

Itonaga H, Ishiyama K, Aoki K, Aoki J, Ishikawa T, Ohashi K, Fukuda T, Ozawa Y, Ota S, Uchida N, Eto T, Iwato K, Ohno Y, Takanashi M, Ichinohe T, Atsuta Y, Miyazaki Y.

Bone Marrow Transplant. 2019 Feb 4. doi: 10.1038/s41409-019-0469-5. [Epub ahead of print]

PMID:
30718803
49.

Progressive Hepatic Cirrhosis Early After Allogeneic Hematopoietic Stem Cell Transplantation in a Patient with Chronic Hepatitis C Infection

Kaito S, Doki N, Hishima T, Takaki Y, Ohashi K.

Turk J Haematol. 2019 May 3;36(2):130-133. doi: 10.4274/tjh.galenos.2019.2018.0224. Epub 2019 Feb 5. No abstract available.

50.

Beneficial Effect of Osimertinib Readministration in Non-small-cell Lung Cancer Harboring an EGFR Mutation With a History of Acquired Resistance to Osimertinib.

Makimoto G, Ohashi K, Senoo S, Hotta K, Maeda Y, Kiura K.

Intern Med. 2019 Feb 1. doi: 10.2169/internalmedicine.2152-18. [Epub ahead of print]

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