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Humulus japonicus extract ameliorates collagen‑induced arthritis in mice through regulation of overall articular inflammation.

Kang EJ, Kim HJ, Choi JH, Noh JR, Kim JH, Lee IB, Choi YK, Choi DH, An J, Oh WK, Kim YH, Lee CH.

Int J Mol Med. 2020 Feb;45(2):417-428. doi: 10.3892/ijmm.2019.4417. Epub 2019 Dec 3.


Development of a Building Block Strategy to Target the Classification, Identification, and Metabolite Profiling of Oleanane Triterpenoids in Gymnema sylvestre Using UHPLC-qTOF/MS.

Pham HT, Kim HW, Han S, Ryu B, Doan TP, An JP, Tran VO, Oh WK.

J Nat Prod. 2019 Dec 27;82(12):3249-3266. doi: 10.1021/acs.jnatprod.9b00328. Epub 2019 Nov 25.


Oleanane hemiacetal glycosides from Gymnema latifolium and their inhibitory effects on protein tyrosine phosphatase 1B.

Pham HTT, Ryu B, Cho HM, Lee BW, Yang WY, Park EJ, Tran VO, Oh WK.

Phytochemistry. 2020 Feb;170:112181. doi: 10.1016/j.phytochem.2019.112181. Epub 2019 Nov 11.


Radiologic and Clinical Outcomes After Hamstring Anterior Cruciate Ligament Reconstruction Using an Adjustable-Loop Cortical Suspension Device With Retensioning and Knot Tying.

Choi NH, Park TH, Oh WK, Victoroff BN.

Arthroscopy. 2019 Sep;35(9):2629-2633. doi: 10.1016/j.arthro.2019.03.029. Epub 2019 Aug 8.


Constituents of the Edible Leaves of Melicope pteleifolia with Potential Analgesic Activity.

Lee BW, Park JG, Ha TKQ, Pham HTT, An JP, Noh JR, Lee CH, Oh WK.

J Nat Prod. 2019 Aug 23;82(8):2201-2210. doi: 10.1021/acs.jnatprod.9b00224. Epub 2019 Aug 8.


Anti-hepatic steatosis activity of Sicyos angulatus extract in high-fat diet-fed mice and chemical profiling study using UHPLC-qTOF-MS/MS spectrometry.

An JP, Choi JH, Huh J, Lee HJ, Han S, Noh JR, Kim YH, Lee CH, Oh WK.

Phytomedicine. 2019 Oct;63:152999. doi: 10.1016/j.phymed.2019.152999. Epub 2019 Jun 27.


Fibroblast Growth Factor Receptor 3 Alterations and Response to PD-1/PD-L1 Blockade in Patients with Metastatic Urothelial Cancer.

Wang L, Gong Y, Saci A, Szabo PM, Martini A, Necchi A, Siefker-Radtke A, Pal S, Plimack ER, Sfakianos JP, Bhardwaj N, Horowitz A, Farkas AM, Mulholland D, Fischer BS, Oh WK, Sharma P, Zhu J, Galsky MD.

Eur Urol. 2019 Nov;76(5):599-603. doi: 10.1016/j.eururo.2019.06.025. Epub 2019 Jul 1.


Hamstring Anterior Cruciate Ligament Reconstruction Using an Adjustable-Loop Cortical Suspension Device: Immediate Postoperative Magnetic Resonance Imaging.

Choi NH, Lee SJ, Oh WK, Victoroff BN.

J Knee Surg. 2019 Jul 3. doi: 10.1055/s-0039-1692648. [Epub ahead of print]


Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade.

Gong Y, Wang L, Yu H, Alpert N, Cohen MD, Prophete C, Horton L, Sisco M, Park SH, Lee HW, Zelikoff J, Chen LC, Hashim D, Suarez-Farinas M, Donovan MJ, Aaronson SA, Galsky M, Zhu J, Taioli E, Oh WK.

Mol Cancer Res. 2019 Aug;17(8):1605-1612. doi: 10.1158/1541-7786.MCR-19-0115. Epub 2019 Jun 20. Erratum in: Mol Cancer Res. 2019 Aug;17(8):1774.


Oligostilbenes from the leaves of Gnetum latifolium and their biological potential to inhibit neuroinflammation.

Cho HM, Quy Ha TK, Tung Pham HT, An JP, Huh J, Lee BW, Lee HJ, Oh WK.

Phytochemistry. 2019 Sep;165:112044. doi: 10.1016/j.phytochem.2019.05.017. Epub 2019 Jun 12.


Programmed Death-1 or Programmed Death Ligand-1 Blockade in Patients with Platinum-resistant Metastatic Urothelial Cancer: A Systematic Review and Meta-analysis.

Niglio SA, Jia R, Ji J, Ruder S, Patel VG, Martini A, Sfakianos JP, Marqueen KE, Waingankar N, Mehrazin R, Wiklund P, Oh WK, Mazumdar M, Ferket BS, Galsky MD.

Eur Urol. 2019 Dec;76(6):782-789. doi: 10.1016/j.eururo.2019.05.037. Epub 2019 Jun 11. Review.


Nectandrin B-mediated activation of the AMPK pathway prevents cellular senescence in human diploid fibroblasts by reducing intracellular ROS levels.

Jang HJ, Yang KE, Oh WK, Lee SI, Hwang IH, Ban KT, Yoo HS, Choi JS, Yeo EJ, Jang IS.

Aging (Albany NY). 2019 Jun 14;11(11):3731-3749. doi: 10.18632/aging.102013.


The evolving landscape of immunotherapy in advanced prostate cancer.

Patel VG, Oh WK.

Immunotherapy. 2019 Jul;11(10):903-912. doi: 10.2217/imt-2019-0019. Epub 2019 Jun 4.


Eudesmane Glycosides from Ambrosia artemisiifolia (Common Ragweed) as Potential Neuroprotective Agents.

An JP, Ha TKQ, Kim HW, Ryu B, Kim J, Park J, Lee CH, Oh WK.

J Nat Prod. 2019 May 24;82(5):1128-1138. doi: 10.1021/acs.jnatprod.8b00841. Epub 2019 Apr 22.


Dereplication of Components Coupled with HPLC-qTOF-MS in the Active Fraction of Humulus japonicus and It's Protective Effects against Parkinson's Disease Mouse Model.

Lee HJ, Dhodary B, Lee JY, An JP, Ryu YK, Kim KS, Lee CH, Oh WK.

Molecules. 2019 Apr 11;24(7). pii: E1435. doi: 10.3390/molecules24071435.


Prenylated Phenolic Compounds from the Leaves of Sabia limoniacea and Their Antiviral Activities against Porcine Epidemic Diarrhea Virus.

Cho HM, Ha TK, Dang LH, Pham HT, Tran VO, Huh J, An JP, Oh WK.

J Nat Prod. 2019 Apr 26;82(4):702-713. doi: 10.1021/acs.jnatprod.8b00435. Epub 2019 Mar 19.


Intraoperative and Postoperative Complications after Arthroscopic Coracoclavicular Stabilization.

Lim TK, Oh WK.

Clin Orthop Surg. 2019 Mar;11(1):103-111. doi: 10.4055/cios.2019.11.1.103. Epub 2019 Feb 18.


Dereplication by High-Performance Liquid Chromatography (HPLC) with Quadrupole-Time-of-Flight Mass Spectroscopy (qTOF-MS) and Antiviral Activities of Phlorotannins from Ecklonia cava.

Cho HM, Doan TP, Ha TKQ, Kim HW, Lee BW, Pham HTT, Cho TO, Oh WK.

Mar Drugs. 2019 Mar 4;17(3). pii: E149. doi: 10.3390/md17030149.


Hydroxyoleoside-type seco-iridoids from Symplocos cochinchinensis and their insulin mimetic activity.

Lee BW, Ha TKQ, Pham HTT, Hoang QH, Tran VO, Oh WK.

Sci Rep. 2019 Feb 19;9(1):2270. doi: 10.1038/s41598-018-38013-4.


12,23-Dione dammarane triterpenes from Gynostemma longipes and their muscle cell proliferation activities via activation of the AMPK pathway.

Ha TKQ, Pham HTT, Cho HM, Tran VO, Yang JL, Jung DW, Williams DR, Oh WK.

Sci Rep. 2019 Feb 4;9(1):1186. doi: 10.1038/s41598-018-37808-9.


Real World Experience of Drug Induced Liver Injury in Patients Undergoing Chemotherapy.

Azad A, Chang P, Devuni D, Bichoupan K, Kesar V, Branch AD, Oh WK, Galsky MD, Ahmad J, Odin JA.

J Clin Gastroenterol Hepatol. 2018;2(3). pii: 18. doi: 10.21767/2575-7733.1000047. Epub 2018 Sep 14.


Four New Compounds Isolated from the Aerial Part of Belamcanda chinensis (L.) and Their Effect on Vascular Smooth Muscle Cell (VSMC) Proliferation.

Ha DT, Binh BT, Thu NT, Bich Thu NT, Thanh Tung PH, Oh WK.

Chem Pharm Bull (Tokyo). 2019;67(1):41-46. doi: 10.1248/cpb.c18-00645.


Sicyos angulatus ameliorates acute liver injury by inhibiting oxidative stress via upregulation of anti-oxidant enzymes.

Kim HY, Noh JR, Moon SJ, Choi DH, Kim YH, Kim KS, Yook HS, An JP, Oh WK, Hwang JH, Lee CH.

Redox Rep. 2018 Dec;23(1):206-212. doi: 10.1080/13510002.2018.1546986.


Insulin Mimetic Activity of 3,4- Seco and Hexanordammarane Triterpenoids Isolated from Gynostemma longipes.

Pham HTT, Ha TKQ, Cho HM, Lee BW, An JP, Tran VO, Oh WK.

J Nat Prod. 2018 Nov 26;81(11):2470-2482. doi: 10.1021/acs.jnatprod.8b00524. Epub 2018 Nov 2.


Flavone glycosides from Sicyos angulatus and their inhibitory effects on hepatic lipid accumulation.

An JP, Dang LH, Ha TKQ, Pham HTT, Lee BW, Lee CH, Oh WK.

Phytochemistry. 2019 Jan;157:53-63. doi: 10.1016/j.phytochem.2018.10.013. Epub 2018 Oct 24.


Trichosanhemiketal A and B: Two 13,14-seco-13,14-epoxyporiferastanes from the root of Trichosanthes kirilowii Maxim.

Ha MT, Phan TN, Kim JA, Oh WK, Lee JH, Woo MH, Min BS.

Bioorg Chem. 2019 Mar;83:105-110. doi: 10.1016/j.bioorg.2018.10.019. Epub 2018 Oct 13.


3,5-Di-C-β-D-glucopyranosyl phloroacetophenone, a major component of Melicope ptelefolia, suppresses fibroblast activation and alleviates arthritis in a mouse model: Potential therapeutics for rheumatoid arthritis.

Kim HJ, Choi JH, Hwang JH, Kim KS, Noh JR, Choi DH, Moon SJ, Kim HY, Kim SW, Choi S, Eum SM, Bach TT, Rho J, Lee JY, Park JG, Oh SR, Lee CH, Oh WK, Kim YH.

Int J Mol Med. 2018 Nov;42(5):2763-2775. doi: 10.3892/ijmm.2018.3849. Epub 2018 Aug 30.


Real-world outcomes in patients with metastatic castration-resistant prostate cancer receiving second-line chemotherapy versus an alternative androgen receptor-targeted agent (ARTA) following early progression on a first-line ARTA in a US community oncology setting.

Oh WK, Cheng WY, Miao R, Vekeman F, Gauthier-Loiselle M, Duh MS, Drea E, Szatrowski TP.

Urol Oncol. 2018 Nov;36(11):500.e1-500.e9. doi: 10.1016/j.urolonc.2018.08.002. Epub 2018 Sep 7.


EMT- and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer.

Wang L, Saci A, Szabo PM, Chasalow SD, Castillo-Martin M, Domingo-Domenech J, Siefker-Radtke A, Sharma P, Sfakianos JP, Gong Y, Dominguez-Andres A, Oh WK, Mulholland D, Azrilevich A, Hu L, Cordon-Cardo C, Salmon H, Bhardwaj N, Zhu J, Galsky MD.

Nat Commun. 2018 Aug 29;9(1):3503. doi: 10.1038/s41467-018-05992-x.


Hypoglycemic triterpenes from Gynostemma pentaphyllum.

Wang J, Ha TKQ, Shi YP, Oh WK, Yang JL.

Phytochemistry. 2018 Nov;155:171-181. doi: 10.1016/j.phytochem.2018.08.008. Epub 2018 Aug 18.


Castration-Resistant Prostate Cancer: AUA Guideline Amendment 2018.

Lowrance WT, Murad MH, Oh WK, Jarrard DF, Resnick MJ, Cookson MS.

J Urol. 2018 Dec;200(6):1264-1272. doi: 10.1016/j.juro.2018.07.090. Epub 2018 Aug 4.


Piperlongumine decreases cognitive impairment and improves hippocampal function in aged mice.

Go J, Park TS, Han GH, Park HY, Ryu YK, Kim YH, Hwang JH, Choi DH, Noh JR, Hwang DY, Kim S, Oh WK, Lee CH, Kim KS.

Int J Mol Med. 2018 Oct;42(4):1875-1884. doi: 10.3892/ijmm.2018.3782. Epub 2018 Jul 18.


Identification of microR-106b as a prognostic biomarker of p53-like bladder cancers by ActMiR.

Lee E, Collazo-Lorduy A, Castillo-Martin M, Gong Y, Wang L, Oh WK, Galsky MD, Cordon-Cardo C, Zhu J.

Oncogene. 2018 Nov;37(44):5858-5872. doi: 10.1038/s41388-018-0367-0. Epub 2018 Jul 3.


Erybraedin A is a potential Src inhibitor that blocks the adhesion and viability of non-small-cell lung cancer cells.

Min HY, Jung Y, Park KH, Oh WK, Lee HY.

Biochem Biophys Res Commun. 2018 Jul 7;502(1):145-151. doi: 10.1016/j.bbrc.2018.05.137. Epub 2018 May 24.


Conessine Treatment Reduces Dexamethasone-Induced Muscle Atrophy by Regulating MuRF1 and Atrogin-1 Expression.

Kim H, Jang M, Park R, Jo D, Choi I, Choe J, Oh WK, Park J.

J Microbiol Biotechnol. 2018 Apr 28;28(4):520-526. doi: 10.4014/jmb.1711.11009.


Profile of apalutamide in the treatment of metastatic castration-resistant prostate cancer: evidence to date.

Chong JT, Oh WK, Liaw BC.

Onco Targets Ther. 2018 Apr 12;11:2141-2147. doi: 10.2147/OTT.S147168. eCollection 2018. Review.


Discrimination of different geographic varieties of Gymnema sylvestre, an anti-sweet plant used for the treatment of type 2 diabetes.

Pham HTT, Hoang MC, Ha TKQ, Dang LH, Tran VO, Nguyen TBT, Lee CH, Oh WK.

Phytochemistry. 2018 Jun;150:12-22. doi: 10.1016/j.phytochem.2018.02.013. Epub 2018 Mar 9.


First-Line Treatment of Hormone-Sensitive Metastatic Prostate Cancer: Is There a Single Standard of Care?

Tsao CK, Oh WK.

J Clin Oncol. 2018 Apr 10;36(11):1060-1061. doi: 10.1200/JCO.2017.77.4315. Epub 2018 Feb 12. No abstract available.


Conessine treatment reduces dexamethasone-induced muscle atrophy by regulating MuRF1 and atrogin-1 expression.

Kim H, Jang M, Park R, Jo D, Choi I, Choe J, Oh WK, Park J.

J Microbiol Biotechnol. 2018 Feb 1. doi: 10.4014.jmb.1711.11009. [Epub ahead of print]


2,2'-Methylenebis (6-tert-butyl 4-methylphenol) enhances the antitumor efficacy of belotecan, a derivative of camptothecin, by inducing autophagy.

Jang M, Kim H, Park R, Jo D, Lee EJ, Oh WK, Park J.

Oncotarget. 2017 Dec 1;8(70):115068-115078. doi: 10.18632/oncotarget.22858. eCollection 2017 Dec 29.


Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer.

McClinch K, Avelar RA, Callejas D, Izadmehr S, Wiredja D, Perl A, Sangodkar J, Kastrinsky DB, Schlatzer D, Cooper M, Kiselar J, Stachnik A, Yao S, Hoon D, McQuaid D, Zaware N, Gong Y, Brautigan DL, Plymate SR, Sprenger CCT, Oh WK, Levine AC, Kirschenbaum A, Sfakianos JP, Sears R, DiFeo A, Ioannou Y, Ohlmeyer M, Narla G, Galsky MD.

Cancer Res. 2018 Apr 15;78(8):2065-2080. doi: 10.1158/0008-5472.CAN-17-0123. Epub 2018 Jan 22.


Sicyos angulatus ameliorates atherosclerosis through downregulation of aortic inflammatory responses in apolipoprotein E-deficient mice.

Kim YH, Noh JR, Hwang JH, Kim KS, Choi DH, An JP, Oh WK, Lee CH.

Exp Ther Med. 2017 Dec;14(6):5863-5870. doi: 10.3892/etm.2017.5271. Epub 2017 Oct 10.


Phase 2 Trial of Gemcitabine, Cisplatin, plus Ipilimumab in Patients with Metastatic Urothelial Cancer and Impact of DNA Damage Response Gene Mutations on Outcomes.

Galsky MD, Wang H, Hahn NM, Twardowski P, Pal SK, Albany C, Fleming MT, Starodub A, Hauke RJ, Yu M, Zhao Q, Sonpavde G, Donovan MJ, Patel VG, Sfakianos JP, Domingo-Domenech J, Oh WK, Akers N, Losic B, Gnjatic S, Schadt EE, Chen R, Kim-Schulze S, Bhardwaj N, Uzilov AV.

Eur Urol. 2018 May;73(5):751-759. doi: 10.1016/j.eururo.2017.12.001. Epub 2017 Dec 13.


Polyoxygenated Steroids from the Sponge Clathria gombawuiensis.

Woo JK, Ha TKQ, Oh DC, Oh WK, Oh KB, Shin J.

J Nat Prod. 2017 Dec 22;80(12):3224-3233. doi: 10.1021/acs.jnatprod.7b00651. Epub 2017 Nov 28.


Recognizing Symptom Burden in Advanced Prostate Cancer: A Global Patient and Caregiver Survey.

Drudge-Coates L, Oh WK, Tombal B, Delacruz A, Tomlinson B, Ripley AV, Mastris K, O'Sullivan JM, Shore ND.

Clin Genitourin Cancer. 2018 Apr;16(2):e411-e419. doi: 10.1016/j.clgc.2017.09.015. Epub 2017 Oct 5.


Web-Based Tool to Facilitate Shared Decision Making With Regard to Neoadjuvant Chemotherapy Use in Muscle-Invasive Bladder Cancer.

Galsky MD, Diefenbach M, Mohamed N, Baker C, Pokhriya S, Rogers J, Atreja A, Hu L, Tsao CK, Sfakianos J, Mehrazin R, Waingankar N, Oh WK, Mazumdar M, Ferket BS.

JCO Clin Cancer Inform. 2017 Nov;1:1-12. doi: 10.1200/CCI.17.00116.


Telemedicine-Enabled Clinical Trial of Metformin in Patients With Prostate Cancer.

Galsky MD, Shahin M, Jia R, Shaffer DR, Gimpel-Tetra K, Tsao CK, Baker C, Leiter A, Holland J, Sablinski T, Mehrazin R, Sfakianos JP, Acon P, Oh WK.

JCO Clin Cancer Inform. 2017 Nov;1:1-10. doi: 10.1200/CCI.17.00044.


C-Methylated Flavonoid Glycosides from Pentarhizidium orientale Rhizomes and Their Inhibitory Effects on the H1N1 Influenza Virus.

Huh J, Ha TKQ, Kang KB, Kim KH, Oh WK, Kim J, Sung SH.

J Nat Prod. 2017 Oct 27;80(10):2818-2824. doi: 10.1021/acs.jnatprod.7b00677. Epub 2017 Oct 6.


PTP1B inhibitors from the seeds of Iris sanguinea and their insulin mimetic activities via AMPK and ACC phosphorylation.

Yang JL, Ha TKQ, Lee BW, Kim J, Oh WK.

Bioorg Med Chem Lett. 2017 Nov 15;27(22):5076-5081. doi: 10.1016/j.bmcl.2017.09.031. Epub 2017 Sep 14.


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